CN1046716C - 供合成用的新中间体和用于制造氨基哌嗪衍生物的方法 - Google Patents

供合成用的新中间体和用于制造氨基哌嗪衍生物的方法 Download PDF

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Publication number
CN1046716C
CN1046716C CN94192956A CN94192956A CN1046716C CN 1046716 C CN1046716 C CN 1046716C CN 94192956 A CN94192956 A CN 94192956A CN 94192956 A CN94192956 A CN 94192956A CN 1046716 C CN1046716 C CN 1046716C
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CN
China
Prior art keywords
compound
aryl
salt
alkyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN94192956A
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English (en)
Chinese (zh)
Other versions
CN1128027A (zh
Inventor
奥照夫
茅切浩
田中洋和
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of CN1128027A publication Critical patent/CN1128027A/zh
Application granted granted Critical
Publication of CN1046716C publication Critical patent/CN1046716C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN94192956A 1993-06-18 1994-06-09 供合成用的新中间体和用于制造氨基哌嗪衍生物的方法 Expired - Fee Related CN1046716C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP172427/93 1993-06-18
JP17242793 1993-06-18

Publications (2)

Publication Number Publication Date
CN1128027A CN1128027A (zh) 1996-07-31
CN1046716C true CN1046716C (zh) 1999-11-24

Family

ID=15941775

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94192956A Expired - Fee Related CN1046716C (zh) 1993-06-18 1994-06-09 供合成用的新中间体和用于制造氨基哌嗪衍生物的方法

Country Status (14)

Country Link
US (1) US5708172A (enExample)
EP (1) EP0704439B1 (enExample)
JP (1) JP3489116B2 (enExample)
KR (1) KR100324040B1 (enExample)
CN (1) CN1046716C (enExample)
AT (1) ATE204264T1 (enExample)
CA (1) CA2165326A1 (enExample)
DE (1) DE69427978T2 (enExample)
DK (1) DK0704439T3 (enExample)
ES (1) ES2158896T3 (enExample)
GR (1) GR3036405T3 (enExample)
PT (1) PT704439E (enExample)
TW (1) TW246672B (enExample)
WO (1) WO1995000502A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6450539B1 (en) * 1994-05-31 2002-09-17 Clive James Bilbie Rewritable erasable labels
BR9812736A (pt) * 1997-10-09 2000-08-22 Fujisawa Pharmaceutical Co Novo processo para produzir derivados de aminopiperazina
AUPP818099A0 (en) * 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US6344358B1 (en) * 1999-05-28 2002-02-05 Fujisawa Pharmaceutical Co., Ltd. Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
EP1340499A4 (en) * 2000-12-07 2006-05-03 Astellas Pharma Inc MEANS FOR REINFORCING THE NOOTROPIC EFFECT

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983606A (en) * 1987-10-12 1991-01-08 Zambon Group S.P.A. Pharmaceutically-active phthalazine compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS3919175B1 (enExample) * 1963-08-23 1964-09-07
US3200120A (en) * 1964-08-05 1965-08-10 Searle & Co Hydrazides of 4-substituted 1-aminopiperazines
US3200121A (en) * 1964-08-05 1965-08-10 Searle & Co Disubstituted-alkanoyl hydrazides of 1-aminopiperazines
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983606A (en) * 1987-10-12 1991-01-08 Zambon Group S.P.A. Pharmaceutically-active phthalazine compounds

Also Published As

Publication number Publication date
DE69427978T2 (de) 2001-11-29
EP0704439B1 (en) 2001-08-16
DE69427978D1 (de) 2001-09-20
GR3036405T3 (en) 2001-11-30
EP0704439A1 (en) 1996-04-03
PT704439E (pt) 2001-12-28
CA2165326A1 (en) 1995-01-05
KR100324040B1 (ko) 2002-07-22
KR960703119A (ko) 1996-06-19
JP3489116B2 (ja) 2004-01-19
ATE204264T1 (de) 2001-09-15
EP0704439A4 (en) 1996-02-19
ES2158896T3 (es) 2001-09-16
DK0704439T3 (da) 2001-10-08
WO1995000502A1 (en) 1995-01-05
TW246672B (enExample) 1995-05-01
US5708172A (en) 1998-01-13
CN1128027A (zh) 1996-07-31

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