CN104647903A - Printing spray head device based on microfluidic chip - Google Patents
Printing spray head device based on microfluidic chip Download PDFInfo
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- CN104647903A CN104647903A CN201510069086.8A CN201510069086A CN104647903A CN 104647903 A CN104647903 A CN 104647903A CN 201510069086 A CN201510069086 A CN 201510069086A CN 104647903 A CN104647903 A CN 104647903A
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Abstract
The invention discloses a printing spray head device based on a microfluidic chip. The printing spray device comprises a chip substrate, wherein at least one material flow passage and a at least one control flow passage are formed in the chip substrate; the material flow passage is used for conveying a printing material; a fluid substance with controllable pressure flows in the control flow passage; the control flow passage and the corresponding material flow passage are intersected and a control valve is formed at an intersection; the control valve comprises a flexible film for isolating the control flow passage from the corresponding material flow passage at the intersection; the flexible film changes shape according to the pressure in the control flow passage to control connection and cutoff of the material flow passage. The printing spray device can alternately print multiple materials through a single spray head in once printing process.
Description
Technical field
The present invention relates to a kind of printing head device based on micro-fluidic chip.
Background technology
The target of microfluidic chip technology (Microfluidics) is the function i ntegration in whole laboratory on microchip, and can repeatedly use.Its device characteristic mainly resulting structure (passage, reative cell and some other functional part) is at least micron order yardstick in a dimension, develops unique analytical performance thus.It has liquid flow controlled, consume sample and reagent few, carry high to analysis speed tenfold hundreds of times, the emphasis application of current job development is life science.
3D prints (3D printing), the i.e. one of rapid shaping technique, is a kind of based on mathematical model file, uses powdery metal or plastics etc. can jointing material, is carried out the technology of constructed object by the mode successively printed.The method of the materials such as the method shaping biomaterial, particularly cell that print with 3D, just makes biological 3D print.It is the field that 3D printing technique studies forefront that biological 3D prints, better in medical domain application prospect.
Jointly being printed on during biological 3D prints of multiple material (such as various kinds of cell material) has important meaning.In order to head it off, the means mainly many nozzle printings machine adopted at present.But many nozzle printings apparatus structure is complicated, cost is higher; When frequently using shower nozzle instead, operating efficiency is lower; There is the site error that many shower nozzles coordinate compensates; And between many shower nozzles, location is interfered, and which has limited the lateral dimension of printout; After exchange, material interface has pimple shape to tie more.
A kind of considerable novel thinking is single shower nozzle and multiple flow passages conveying material, by controlling the opening and closing of runner, changes the material that nozzle printing is used.But easily there is liquid material mixing in the runner of macro-size, causes the mutual pollution of not same material.
Summary of the invention
Main purpose of the present invention is for the deficiencies in the prior art, provides a kind of ejecting device based on micro-fluidic chip, the printing of the multiple material that can be hocketed by single shower nozzle in a print procedure.
For achieving the above object, the present invention is by the following technical solutions:
A kind of printing head device based on micro-fluidic chip, comprise chip basal body, described chip basal body is provided with at least one material runner and at least one and controls runner, described material runner is for carrying printed material, the flowing material that in described control runner, circulating pressure is controlled, described control runner is staggered with corresponding material runner and at intervening portion formation control valve, described control valve comprises the fexible film separated at intervening portion with corresponding material runner by described control runner, described fexible film produces deformation according to the pressure in described control runner, control the conducting of described material runner and block.
Further:
Described printing head device comprises many described material runner, and wherein portion of material runner or all material runner are provided with corresponding described control valve, and each material runner meets at converges runner, described in converge runner through delivery channel connection outlet.
Described material runner is less than 100 microns at the height at described control valve place, is greater than 50 microns.
The width of described material runner is 100-200 micron.
The width of described control runner is 200-300 micron.
The described width converging runner is 100-200 micron.
The width of described delivery channel is 100-200 micron.
The PDMS film of described fexible film to be thickness be 30-80 micron.
Described printed material is metal or plastics or biomaterial, and described biomaterial can be the fluent material containing support, nutrient solution or cell etc.
Described material runner is gradually narrow trapezoidal along the direction away from described control runner at the cross section at described intervening portion place.
Described flowing material is gas or the liquid that density is less than described printed material, and described control runner is positioned at above described material runner at described intervening portion place.
Beneficial effect of the present invention:
Printing head device based on micro-fluidic chip of the present invention, can be realized hocketing in a print procedure with single shower nozzle the printing of multiple material, by controlling the gas/liquid pressure controlled in runner, make the deformation of fexible film to control the opening and closing of material runner, change the material that shower nozzle sprays, and the specific properties that liquid shows under micron order size is as capillarity, can prevent different liquid materials from mixing in runner preferably, effectively avoid the mutual pollution of not same material, for biological file printing technology provides good engineering support.Printing head device of the present invention have be quick on the draw, low, the advantage such as material contamination is little, plant bulk is less of controlling cost.Ejecting device of the present invention can directly be provided on existing 3D biometric print machine, realizes the controlled printing of many materials of single spraying head multiple flow passages, is with a wide range of applications.
Accompanying drawing explanation
Fig. 1 and Fig. 2 is the monnolithic case schematic diagram of the ejecting device that the preferred embodiments of the present invention provide, and Fig. 1 is overall appearance, and Fig. 2 is the perspective view of show internal structure.
Fig. 3 and Fig. 4 is material runner in embodiment and the planar structure schematic diagram controlling runner respectively.
Fig. 5 is the perspective view of the control valve in embodiment.
Fig. 6 a is the material runner opening schematic cross-section in embodiment, and Fig. 6 b is that the material runner in embodiment closes shape cross section state schematic diagram;
The demonstration graph of Fig. 7 working control example.
Detailed description of the invention
Below in conjunction with accompanying drawing, embodiments of the present invention are elaborated.It is emphasized that following explanation is only exemplary, instead of in order to limit the scope of the invention and apply.
In some embodiments, based on the ejecting device of micro-fluidic chip structure as shown in Figures 1 to 7.Ejecting device comprises chip basal body 100 and is formed at material runner 200, control runner 300 and the control valve 400 in chip basal body 100.Wherein, control runner 300 and interlock with material runner 200 and be spatially positioned at above material runner 200, both staggered places are formed with control valve 400.Each runner is enclosed construction except gateway.In figure, importation and the control runner of material runner all have 5 tunnels, one_to_one corresponding.Certainly, also can only for part, the material runner of not all arrange and control runner accordingly, thus at least control action is played to the material runner of this portion of material.The driving of material runner can adopt syringe pump or peristaltic pump, control runner and control valve can adopt gases at high pressure/liquid as operation material, directly do not contact with the liquid material in material passage in the course of the work, control runner can adopt pneumatic/hydraulic to drive to the driving of control valve.
Preferably, the density of the pressure-air/liquid of employing is less than printed material, in staggered place, controls runner and is spatially positioned at above material runner 200.
As shown in Figure 1, chip basal body 100 is provided with the entrance 101 of material runner 200, controls the gateway 102 of runner 300 and the outlet 103 of material runner 200.The upper surface with macro-scale of chip basal body 100 is preferably located in the entrance of material runner 200 and the gateway of control runner 300, and the outlet of material runner 200 can be arranged at the arbitrary surfaces of chip basal body 100.
As shown in Figure 3, material runner 200 comprises input duct 201, control valve part 202, converges runner 203 and delivery channel 204.
As shown in Figure 4, control can pass into pressure-air in runner 300, control runner 300 and comprise pressure-air input duct 301, control valve part 302 and pressure-air delivery channel 303.
As shown in Figure 5, control valve 400 is included in the control runner section 401, fexible film 402 and the material runner part 403 that control runner 300 and the intervening portion of material runner 200, be formed as valve arrangement, fexible film 402 separates two runners, and deformation can be produced according to the pneumatic/hydraulic controlling runner, control the conducting of material runner 200 thus and block.Fexible film 402 preferably adopts has deformability and the rear restorative stronger thin-film material of distortion, control runner and material runner separate by it, the bend by pressure when controlling gas/liquid pressure increase in runner plugging material runner, realize runner and close, otherwise open.Preferably, flexible thin-film material is PDMS (dimethyl silicone polymer), and thickness should be little as far as possible, is 30-80 micron.
Preferably, the input duct of each material runner, the shape converging runner, size are close, and delivery channel can be slightly wide, so that reduce systematic error when controlling runner opening and closing.
The operation principle of the controlled printing of many materials is as follows.
See Fig. 3, various material is inputted by each input duct entrance respectively with certain hydraulic pressure P1, controls through control valve, and synchronization only has a kind of material to flow into assemble jamming road, and by delivery channel outlet flow to spray outlet.
See Fig. 4, the gas that the pressure P that controls to flow all the time in runner is controlled or liquid working substance, realized the control of material runner by controlled medium pressure, direction as shown in the figure.
See Fig. 6 a and Fig. 6 b, when the gas in certain road control runner section 401 or liquid pressure P are greater than the Liquid transfer pressure P1 in material runner part 403 and this pressure critical value of pressure P2 sum needed for the complete deformation of fexible film 402 (P>P1+P2), material runner 403 can be made to block, otherwise conducting.The strong P of actual controlled superzapping is far longer than critical value (i.e. P>>P1+P2) to realize reliably blocking of material runner 403.By controlling the pressure P of each control runner, the fluid of each material runner 403 can be controlled.
In a preferred embodiment, the cross section of material runner part 403 is that this is designed with to be beneficial to and makes fexible film 402 plugging material runner completely when controlling material runner and closing along gradually narrow trapezoidal away from the direction controlling runner section 401.
As Fig. 7, can according to diagram C-D-A-D sequential control valve open (during a valve opening, other valves are all closed), delivery channel obtain liquid stream c-d-a-d as diagram.
Material runner height is preferably less than 100 microns.Close down on the basis of condition satisfied, the height of material runner can be greater than 50 microns, blocks to avoid runner.
Preferably, each flow channel entry point, in the surrounding of chip basal body, converges runner and is positioned at chip basal body side, near outlet.Control flow check road shape is preferably U-shaped, and entrance is located at material runner entrance both sides with outlet point.
Preferably, converge the wide 100-200 micron of runner, input duct and the wide 100-200 micron of delivery channel, control the wide 200-300 micron of runner, the wide 100-200 micron of control valve place material runner.
Preferably, material runner height can select 50 microns.Control valve place material runner length and width all select 300 microns.
The material of chip basal body can be glass, and processing mode is the micro Process based on photoetching.
By adopting the structural design of above-mentioned multiple flow passages and control valve on micro-fluidic chip, the controlled printing of material more than single spraying can be realized preferably, and have be quick on the draw, low, the advantage such as material contamination is little, plant bulk is less of controlling cost, be easy to apply on existing cell printing machine.
Above content combines concrete/preferred embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention; without departing from the inventive concept of the premise; its embodiment that can also describe these makes some substituting or modification, and these substitute or variant all should be considered as belonging to protection scope of the present invention.
Claims (10)
1. the printing head device based on micro-fluidic chip, it is characterized in that, comprise chip basal body, described chip basal body is provided with at least one material runner and at least one and controls runner, described material runner is for carrying printed material, the flowing material that in described control runner, circulating pressure is controlled, described control runner is staggered with corresponding material runner and at intervening portion formation control valve, described control valve comprises the fexible film separated at intervening portion with corresponding material runner by described control runner, described fexible film produces deformation according to the pressure in described control runner, control the conducting of described material runner and block.
2. printing head device as claimed in claim 1, it is characterized in that, comprise many described material runner, wherein portion of material runner or all material runner are provided with corresponding described control valve, each material runner meets at converges runner, described in converge runner through delivery channel connection outlet.
3. printing head device as claimed in claim 1 or 2, it is characterized in that, described material runner is less than 100 microns at the height at described control valve place, is greater than 50 microns.
4. printing head device as claimed in claim 1 or 2, it is characterized in that, the width of described material runner is 100-200 micron.
5. printing head device as claimed in claim 1 or 2, it is characterized in that, the width of described control runner is 200-300 micron.
6. printing head device as claimed in claim 2, is characterized in that, described in converge runner and/or described delivery channel width be 100-200 micron.
7. the printing head device as described in any one of claim 1 to 6, is characterized in that, described printed material is metal or plastics or biomaterial, and described biomaterial can be the fluent material containing support, nutrient solution or cell etc.
8. the printing head device as described in any one of claim 1 to 6, is characterized in that, the PDMS film of described fexible film to be thickness be 30-80 micron.
9. the printing head device as described in any one of claim 1 to 6, is characterized in that, described material runner is gradually narrow trapezoidal along the direction away from described control runner at the cross section at described intervening portion place.
10. the printing head device as described in any one of claim 1 to 6, is characterized in that, described flowing material is gas or the liquid that density is less than described printed material, and described control runner is positioned at above described material runner at described intervening portion place.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510069086.8A CN104647903B (en) | 2015-02-09 | 2015-02-09 | A kind of printing head device based on micro-fluidic chip |
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| CN201510069086.8A CN104647903B (en) | 2015-02-09 | 2015-02-09 | A kind of printing head device based on micro-fluidic chip |
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| CN104647903A true CN104647903A (en) | 2015-05-27 |
| CN104647903B CN104647903B (en) | 2016-07-06 |
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| CN201510069086.8A Expired - Fee Related CN104647903B (en) | 2015-02-09 | 2015-02-09 | A kind of printing head device based on micro-fluidic chip |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105238676A (en) * | 2015-10-15 | 2016-01-13 | 清华大学深圳研究生院 | Microfluidic chip for cell printing |
| CN105925479A (en) * | 2016-04-25 | 2016-09-07 | 清华大学深圳研究生院 | Gradient 3D printing head and 3D printer |
| JP2017024322A (en) * | 2015-07-24 | 2017-02-02 | セイコーエプソン株式会社 | Flow passage structure and liquid injection head |
| CN107937270A (en) * | 2017-11-17 | 2018-04-20 | 清华大学深圳研究生院 | A kind of micro-fluidic chip nozzle and biological 3D printer |
| CN108953758A (en) * | 2018-10-09 | 2018-12-07 | 河海大学常州校区 | A kind of microfluidic valve and its microfluid regulate and control method |
| CN109822898A (en) * | 2019-03-18 | 2019-05-31 | 清华大学 | It is a kind of for the mini sprinkler device of biological 3D printer and its application |
| CN110355991A (en) * | 2018-04-09 | 2019-10-22 | 北京大学 | 3D printing method and 3D printing equipment |
| CN110891764A (en) * | 2017-03-15 | 2020-03-17 | 安斯百克特生物系统公司 | System and method for printing fibrous structures |
| CN111148577A (en) * | 2017-09-27 | 2020-05-12 | 杜尔系统股份公司 | Applicator with sealing film |
| KR20200060714A (en) * | 2017-09-27 | 2020-06-01 | 듀르 시스템스 아게 | Applicators with short nozzle spacing |
| CN114720653A (en) * | 2022-05-24 | 2022-07-08 | 武汉正元环境科技股份有限公司 | Water quality detection method and device based on micro-flow control chip |
| US11673149B2 (en) | 2017-09-27 | 2023-06-13 | Dürr Systems Ag | Applicator with a small nozzle distance |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080003404A1 (en) * | 2006-06-30 | 2008-01-03 | 3M Innovative Properties Company | Flexible circuit |
| EP1671798B1 (en) * | 2004-12-20 | 2011-04-13 | Palo Alto Research Center Incorporated | Low cost piezo printhead based on microfluidics in printed circuit board and screen-printed piezoelectrics |
| CN102428204A (en) * | 2009-03-25 | 2012-04-25 | 密执安州立大学董事会 | Compact organic vapor jet printing print head |
| CN102490470A (en) * | 2011-12-07 | 2012-06-13 | 北京清科奥博仪器设备有限公司 | Method and device for controlling tiny droplet spraying by airflows |
| CN102527280A (en) * | 2012-01-11 | 2012-07-04 | 华中科技大学 | Micro mixing and micro reaction device |
| CN102935391A (en) * | 2012-10-23 | 2013-02-20 | 中国科学院大连化学物理研究所 | Method and application for manufacturing microfluidic chip with inkjet printing channels as template |
| CN104004652A (en) * | 2014-06-16 | 2014-08-27 | 东南大学 | Method for manufacturing digital PCR liquid drop array chip based on single-jet ink-jet printing |
-
2015
- 2015-02-09 CN CN201510069086.8A patent/CN104647903B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1671798B1 (en) * | 2004-12-20 | 2011-04-13 | Palo Alto Research Center Incorporated | Low cost piezo printhead based on microfluidics in printed circuit board and screen-printed piezoelectrics |
| US20080003404A1 (en) * | 2006-06-30 | 2008-01-03 | 3M Innovative Properties Company | Flexible circuit |
| CN102428204A (en) * | 2009-03-25 | 2012-04-25 | 密执安州立大学董事会 | Compact organic vapor jet printing print head |
| CN102490470A (en) * | 2011-12-07 | 2012-06-13 | 北京清科奥博仪器设备有限公司 | Method and device for controlling tiny droplet spraying by airflows |
| CN102527280A (en) * | 2012-01-11 | 2012-07-04 | 华中科技大学 | Micro mixing and micro reaction device |
| CN102935391A (en) * | 2012-10-23 | 2013-02-20 | 中国科学院大连化学物理研究所 | Method and application for manufacturing microfluidic chip with inkjet printing channels as template |
| CN104004652A (en) * | 2014-06-16 | 2014-08-27 | 东南大学 | Method for manufacturing digital PCR liquid drop array chip based on single-jet ink-jet printing |
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017024322A (en) * | 2015-07-24 | 2017-02-02 | セイコーエプソン株式会社 | Flow passage structure and liquid injection head |
| CN105238676B (en) * | 2015-10-15 | 2017-04-05 | 清华大学深圳研究生院 | A kind of micro-fluidic chip for cell printing |
| CN105238676A (en) * | 2015-10-15 | 2016-01-13 | 清华大学深圳研究生院 | Microfluidic chip for cell printing |
| CN105925479B (en) * | 2016-04-25 | 2018-08-24 | 清华大学深圳研究生院 | A kind of gradient 3D printing nozzle and 3D printer |
| CN105925479A (en) * | 2016-04-25 | 2016-09-07 | 清华大学深圳研究生院 | Gradient 3D printing head and 3D printer |
| CN110891764A (en) * | 2017-03-15 | 2020-03-17 | 安斯百克特生物系统公司 | System and method for printing fibrous structures |
| CN110891764B (en) * | 2017-03-15 | 2022-04-26 | 安斯百克特生物系统公司 | System and method for printing fibrous structures |
| US11207698B2 (en) | 2017-09-27 | 2021-12-28 | Dürr Systems Ag | Applicator comprising a sealing membrane |
| KR102588319B1 (en) * | 2017-09-27 | 2023-10-12 | 듀르 시스템스 아게 | Applicator with short nozzle spacing |
| US11745194B2 (en) | 2017-09-27 | 2023-09-05 | Dürr Systems Ag | Applicator comprising a sealing membrane |
| US11673149B2 (en) | 2017-09-27 | 2023-06-13 | Dürr Systems Ag | Applicator with a small nozzle distance |
| US11511291B2 (en) | 2017-09-27 | 2022-11-29 | Dürr Systems Ag | Applicator with a small nozzle distance |
| CN111148577A (en) * | 2017-09-27 | 2020-05-12 | 杜尔系统股份公司 | Applicator with sealing film |
| KR20200060714A (en) * | 2017-09-27 | 2020-06-01 | 듀르 시스템스 아게 | Applicators with short nozzle spacing |
| CN111526948A (en) * | 2017-09-27 | 2020-08-11 | 杜尔系统股份公司 | Applicator with short nozzle distance |
| CN107937270A (en) * | 2017-11-17 | 2018-04-20 | 清华大学深圳研究生院 | A kind of micro-fluidic chip nozzle and biological 3D printer |
| CN110355991A (en) * | 2018-04-09 | 2019-10-22 | 北京大学 | 3D printing method and 3D printing equipment |
| CN108953758A (en) * | 2018-10-09 | 2018-12-07 | 河海大学常州校区 | A kind of microfluidic valve and its microfluid regulate and control method |
| CN108953758B (en) * | 2018-10-09 | 2019-09-10 | 河海大学常州校区 | A kind of microfluidic valve and its microfluid regulate and control method |
| CN109822898B (en) * | 2019-03-18 | 2020-09-15 | 清华大学 | Micro-nozzle device for biological 3D printer and application thereof |
| CN109822898A (en) * | 2019-03-18 | 2019-05-31 | 清华大学 | It is a kind of for the mini sprinkler device of biological 3D printer and its application |
| CN114720653A (en) * | 2022-05-24 | 2022-07-08 | 武汉正元环境科技股份有限公司 | Water quality detection method and device based on micro-flow control chip |
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