CN104645243A - Traditional Chinese medicine composition for treating meningioma and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating meningioma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating meningioma. The traditional Chinese medicine composition consists of rhizoma pinellinae praeparata, rhizoma typhonii, bile arisaema, rhizoma gastrodiae, rhizoma acori graminei, radix curcumae, fructus trichosanthis, tangerine peel, fructus aurantii immaturus, semen brassicae, herba asari, cassia seed, flos chrysanthemi, polyporus umbellatus, rhizoma alismatis, Indian iphigenia bulb, uncaria rhynchophylla, centipede, caesalpinia sappan, livistona chinensis, herb of wusheng clematis, paris polyphylla and rhizoma smilacis glabrae according to a certain weight proportion. The traditional Chinese medicine composition has the functions of clearing heat, resolving phlegm, calming endogenous wind, relieving convulsion, opening orifice, eliminating phlegm, moving qi and resolving stasis and can be used for effectively treating meningioma.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of meningioma.The invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Meningioma (Meningiomas) is the derivant originating from meninges and spatium interdurale, and sickness rate accounts for 19.2% of intracranial tumor, and occupy the 2nd, women: male is 2:1, the onset peak age, child was rare at 45 years old.Many asymptomatic meningiomies mostly are and chance on.Multiple meningiomas is visible once in a while, has the report of family history in document.50% is positioned at Parasagittal sinus, another convexity of brain, and falx cerebri side person is common, is secondly the positions such as sphenoid rige, tuberculum sellae, olfactory sulcus, cerebellopontine angle and tentorium of cerebellum, grows Intraventricular person little, also shows in epidural.Other position is accidental.The pathogenic factor of meningioma may change relevant with genovariation with certain environment, and not single factors causes, may with craniocerebral trauma, radio exposure, viral infection and to merge the factors such as Bilateral Acoustic Neroumas relevant.It has been generally acknowledged that the split speed of Arachnoid cells is very slow, appeal factor accelerates the split speed of cell, may be the early stage important stage causing cytopathy.The main clinical manifestation of meningioma is: meningioma belongs to benign tumor, and growth is slow, and the course of disease is long.Because tumor is expansive growth, patient often with headache and epilepsy for onset symptoms.Different according to knub position, vision, the visual field, olfactory sensation or dysacousis and limb movement disturbance etc. can also be there is.Old people, be that onset symptoms is common especially with epilepsy.It is how not obvious that cranium pressure increases symptom, especially at Aged Patients.When CT examination is popularized day by day, many patients only have slight headache, even chance on as meningioma through CT scan.Because tumor growth is slow, so tumor is often long very large, and clinical symptoms is also not serious.The meningioma closing on skull often can cause the change of sclerotin.
Current excision meningioma is the most frequently used method, but because of its growth position, about has the meningioma of 17%-50% not accomplish entirely to cut, and also has minority malignant meningioma also cannot entirely cut in addition.This to carry out radiotherapy.Perform the operation and a huge test is undoubtedly for the health send a letter here of old people; household not only will bear expensive operation and postoperative medical expense; also to bear in corrective surgery process all risks run into simultaneously; and excision not exclusively also has the risk of recurrence, make very large pressure to the body & mind of patient.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has evident in efficacy for treatment meningioma, cheap, has no side effect, the feature not easily recurred.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment meningioma.
Inventor is in clinical treatment practice for many years, observe the misery that meningioma brings to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of meningioma repeatedly, the selection method Rhizoma Pinelliae of the present invention, Rhizoma Typhonii, Arisaema Cum Bile, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Radix Curcumae, Fructus Trichosanthis, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Semen Sinapis Albae, Herba Asari, Semen Cassiae, Flos Chrysanthemi, Polyporus, Rhizoma Alismatis, Pseudobulbus Cremastrae Seu Pleiones, Ramulus Uncariae Cum Uncis, Gekko Swinhonis, Lignum Sappan, seed of Livistona chinensis R.Br., Herba Clematidis Huchouensis, Rhizoma Paridis, Rhizoma Smilacis Glabrae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is removing heat-phlegm, dispelling wind and relieving convulsion, to have one's ideas straightened out eliminating phlegm, effect of regulating qi to disperse stagnation, thus effectively can treat meningioma.
The effect of Chinese medicine of the present invention:
Wherein:
Rhizoma Pinelliae Preparatum: the Rhizoma Pinelliae is the tuber at the Rhizoma Arisaematis section plant Rhizoma Pinelliae (Pinellia ternata (Thunb.) Breit.).The clean Rhizoma Pinelliae got by Rhizoma Pinelliae Preparatum, with cold water leaching drift, avoids Exposure to Sunlight, and according to its place of production quality and granular size thereof, number of days is soaked in consideration adjustment.Steep after 10 days, during as played foam, every Rhizoma Pinelliae 100 jin adds Alumen 2 jin, steeps after 1 day and carries out changing water again, tastes slightly spicy sense for degree, take out and slightly dry in the air to mouth.Another extracting liquorice is ground into thick block, adds decocting soup, steeps lime block with glycyrrhiza decoction, then the mixing that adds water, and removing lime mud, pours in Rhizoma Pinelliae cylinder and soak, and every day stirs, and makes its color even, and to yellow, oneself soaks into, interior without Bai Xinwei degree.Pull out, dry in the shade.Nature and flavor: pungent, temperature, poisonous.Enter spleen, stomach warp.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Modern clinic is mainly used in various tumor.
Rhizoma Typhonii: be the dry tuber of aroid Herba Typhonii gigantei Typhonium giganteum Engl..Nature and flavor: pungent, warm, poisonous.Return stomach, Liver Channel.Effect: dispel the wind expectorant, and arresting convulsion is jerked, detoxicating and resolving stagnation of pathogens pain relieving.Stop up for middle wind-phlegm, facial hemiparalysis, language is puckery stuttering, and syncope due to accumulation of phlegm is had a headache, migraine and general headache, sore throat pharyngalgia, tetanus; External treatment scrofula sucutaneous nodule, venom, tetanus, carbuncle.
Arisaema Cum Bile: for the fine powder of Rhizoma Arisaematis (processed) and cattle, sheep or Fel Sus domestica process from strand, or form through fermentation processing for Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica.Nature and flavor: bitter, cold, micro-pungent, cool.Return lung, liver, spleen channel.Effect: removing heat-phlegm, dispelling wind and relieving convulsion.This product can control middle wind-phlegm fan, infantile convulsion epilepsy, and phlegm-fire is breathed heavily and coughed, phlegm-accumulating vertigo.Record in " medicineization justice ": " cure mainly all apoplexy, acute infantile convulsion, infantile convulsion, wind syndrome of head, dizzy, old god is slow-witted, and children's sends out and jerks, puerperal severe palpitation." " book on Chinese herbal medicine converge with speech ": Rhizoma Arisaematis, forefathers with Fel Bovis seu Bubali system it, name says Arisaema Cum Bile.Fel Bovis seu Bubali bitter cold and moistening, has the merit that the liver benefiting is relieving convulsion, star processed dry and make not malicious.
Rhizoma Gastrodiae: be the dry tuber of orchid Rhizoma Gastrodiae Gastrodia elata Blume..Nature and flavor: sweet are flat.Return Liver Channel.Effect: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.Pharmaceutical research shows, Rhizoma Gastrodiae has significantly calm and anticonvulsant action.Rhizoma Gastrodiae is sweet flat, specially enter Liver Channel, function endogenous wind stopping relieving convulsion, and Gan Run is not strong, acts on gentle, the panacea of endogenous wind for it, can be used for treating the liver-wind stirring up internally caused by the various cause of disease, and infantile convulsion is twitched, no matter cold and heat and asthenia and sthenia, and all can compatibility application.
Rhizoma Acori Graminei: be the dry rhizome of acorus gramineus araceae plant Acorus tatarinowii Schott.Nature and flavor: pungent, bitter, temperature.GUIXIN, stomach warp.Effect: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Rhizoma Acori Graminei has anticonvulsant action, and the volatile oil of Rhizoma Acori Graminei has sedation of calming the nerves, and Rhizoma Acori Graminei decoct takes the secretion of energy facilitating digestion liquid orally." herbal classic ": " happy hole, tonifying five ZANG-organs, logical nine orifices, improve visual and auditory acuity, goes out speech for main anemofrigid-damp arthralgia, cough with dyspnea." " Chongqing hall random notes ": Rhizoma Acori Graminei, comfortable gas, the smooth mind, happy mood, beneficial will, panacea also.Removing summer-heat medicinal it, relying, it is dirty turbid and defend city wall to eliminate the phlegm, nourish medicinal it, so as to declaring the knot of thought and being proficient in the law of natural movement.
Radix Curcumae: be the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor: pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.Cure mainly: all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.The pungent loose hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.Radix Curcumae pungent drugs can disperse and bitter drugs can descend, fragrance a surname reach, cold in nature again can heat clearing away.Both having entered edema caused by disorder of QI with promoting QI circulation for relieving depression, and entered again blood system with cooling blood and dissolving stasis, is the gas medicine in blood.
Fructus Trichosanthis: be the dry mature seed of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosanthes rosthornii Harms.Nature and flavor: sweet, bitter, cold.Enter lung, stomach, large intestine channel.Effect: moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving, eliminating stagnation, intestine moistening.This product and the Rhizoma Pinelliae, again can relieving stuffiness of the chest by dispersing aggregation of pathogens with can Qinghua heat-phlegm, and use same with Fructus Aurantii Immaturus, has the merit of removing heat from the lung and dissipating phlegm.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.Nature and flavor: temperature are pungent, bitter.Enter spleen, stomach, lung meridian.Effect: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.This product temperature can circulation of qi promoting, pungently can disperse, bitter and sluice.Pericarpium Citri Reticulatae and the same use of Fructus Aurantii Immaturus, acrid in the mouth circulation of qi promoting, fragrance enters spleen, therefore can promoting the circulation of QI to relieve pain, spleen invigorating and in, Pericarpium Citri Reticulatae and the Rhizoma Pinelliae can drying dampness to eliminate phlegm with use, again can warming for resolving cold-phlegm.
Fructus Aurantii Immaturus: be the dry young fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety or Fructus Citri sinensis Citrus sinensis Osbeck.Nature and flavor: bitter, acrid, cold.Return spleen, stomach, liver, heart channel.Effect: dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Cure mainly: weight, blocked-up chest, gastroptosis, uterine prolapse, proctoptosis after feeling of fullness distending pain, constipation, dysentery.This product can be regulated the flow of vital energy, and can reduce phlegm again, can join Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, the equivalent use of Rhizoma Gastrodiae for dizziness due to wind-phlegm etc.
Semen Sinapis Albae: the dry mature seed of Cruciferae 1 year or biennial plant Caulis et Folium Sinapis albee SinapisalbaL..Nature and flavor: pungent, warm.Attach to the lung and stomach meridians.Effect: promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.Record in essentials of Matea Medica: Semen Sinapis Albae, a surname, promoting the circulation of QI eliminating phlegm.Xin Wen enters lung.Current meridians, warming middle-JIAO whets the appetite, diaphoresis cold expelling, promoting the circulation of QI eliminating phlegm, reducing swelling and alleviating pain.Expectorant is capable, swells and disappears, and the capable then pain of gas only.For non-vinegar dresses, subduing inflammation.
Herba Asari: be aristolochiaceae plant Herba Asari Asarum heterotropoides Fr. Schmidt var.mandshuricum(Maxim.) the dry herb of Kitag., Seoul Herba Asari Asarum sieboldii Miq. var. seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..Nature and flavor: pungent; Temperature; Mild toxicity.Return lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel.Effect: mass dissipating and swelling eliminating; Induce sweat cold expelling; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm, sensible.Antibacterial, antivirus action kakuol preserved material, volatilization wet goods have certain In-vitro Inhibitory Effect to gram positive bacteria, bacillus subtilis and Bacillus typhi, and decoct also has inhibitory action to tubercule bacillus and Bacillus typhi.Herba Asari volatile oil is to multiple fungus as Aspergillus flavus, Aspergillus niger, Candida albicans etc. all have inhibitory action, and antibacterial effective ingredient is safrole.α-asaricin has the effect suppressing respiratory syncytial virus propagation.
Semen Cassiae: be the dry mature seed of leguminous plant Semen Cassiae Cassia obtusifolia L. or little Semen Cassiae Cassia tora L..Nature and flavor: sweet, bitter, salty, are slightly cold.Return liver, large intestine channel.Effect: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation." book on Chinese herbal medicine justice ": Semen Cassiae improving eyesight, being grow liver and kidney tonifying, with tranquillizing and subduing nourishing YIN for justice, is the routine treatment of reinforcing, non-as the pungent loose wind of temperature, and cold and cool what fall heat is only that secondary disease legislator is comparable, has every advantage and not a single disadvantage the most.
Flos Chrysanthemi: be the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Effect: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.This product can clearing away liver-fire, and wind heat of faling apart again is the common medicine of heat-clearing and toxic substances removing.
Polyporus: be the dry sclerotia of On Polyporaceae Polyporus Polyporus umbellatus (Pers.) Fries.Nature and flavor: sweet, light, flat.Return kidney, urinary bladder channel.Effect: promoting diuresis to eliminate damp pathogen.Polyporus and Poria compatibility, Polyporus specializes in promoting diuresis to eliminate damp pathogen, and diuretic effect is strong in Poria.
Rhizoma Alismatis: be the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..Nature and flavor: sweet, cold.Return kidney, urinary bladder channel.Effect: diuresis, clearing away damp-heat.For edema, the dysuria of retention of water-damp in the body.This product enters kidney, urinary bladder channel, kind clear damp-heat in lower-JIAO cold in nature.In addition to staphylococcus aureus, Diplococcus pneumoniae, tubercule bacillus has inhibitory action.
Pseudobulbus Cremastrae Seu Pleiones: be the dry pseudobulb of orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides (Franch.) Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Nature and flavor: sweet, pungent, cold, mild toxicity.Return liver, stomach, lung meridian.Effect: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.This product has the merit of detoxicating and resolving stagnation of pathogens detumescence, in recent years this product Guang general ground Yu mass in the abdomen mass in the abdomen and kinds of tumors.Normal and the Rhizoma Pinelliae, Spica Prunellae are used together.
Ramulus Uncariae Cum Uncis: be the dry stem and branch with belt hook of Maguireothamnus speciosus Ramulus Uncariae Cum Uncis Uncaria rhynch0phylla (Miq.) Jacks., Ramulus Uncariae macrophyllae Uncaria macrophylla Wall., Ramulus Uncariae Cum Uncis Uncaria hirsuta Havil., Uncaria sinensis (Oliv.) Havil. Uncaria sinensis (Oliv.) Havil. or stockless fruit Ramulus Uncariae Cum Uncis Uncaria sessilifructus Roxb..Nature and flavor: sweet are cool.Return liver, pericardium channel.Effect: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Dizzy for having a headache, dysphoric cold, infantile convulsion is twitched, pre-eclampsia; Hypertension."Ben hui said:" teng, wind phlegm and arresting convulsion, chronic, Ann guest mind blain of drug attack.Mr. Qian Zhongyang says: an ancient unit of weight rattan, warm, flat, nontoxic, baby section treasure's.Their sexual chik lee, wind phlegm, KaiQi closed, Ann chronic ulcerated in haste in an instant, with internal accumulation of cold, hemp, GuiFa with Qin, solution of severe heat, like the previous, remove the table of evil, with check, park long lag of food, with rat glue, platycodon grandiflorum, qiang, prevent, loc hair blain cuo ambiguously not now, but not dry wind evil, and to and in the article.But decoct just unable for a long time, his medicine fry cooked more than ten of waiting is boiled, drop into and namely rise, quite also capable.Destemmingly purely use tender hook, power ten times.
Gekko Swinhonis: for Geckonidae animal is all without the drying of wart Gekko Swinhonis Gekko subpalmatus Gunther or other several Gekko Swinhonis.Nature and flavor: salty, cold, slightly poisonous.Enter Liver Channel.Effect: dispel the wind, active, eliminating stagnation.For paralysis due to windstroke, rheumatic arthritis, osteomyelitis, tuberculous lymphadenitis, tumor.Be used for the treatment of the kinds cancers such as esophageal carcinoma, intestinal cancer, primary hepatocarcinoma, pulmonary carcinoma clinically at present.
Lignum Sappan: be the dry duramen of leguminous plant Lignum Sappan (Caesalpinia sappanL.).Nature and flavor are sweet, salty, pungent, cool.GUIXIN; Liver; Stomach; Spleen channel.Effect: blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.
Seed of Livistona chinensis R.Br.: be Palmae Livistona plant Semen livistonae chinensis Livistona chinensis R. Brown, seed.Nature and flavor: sweet, puckery are flat.Effect: anticancer.For esophageal carcinoma, chorionic epithelioma, malignant mole, leukemia.Modern clinic is used for treating various cancer.
Herba Clematidis Huchouensis: be Ranunculaceae Actions of Clematis Species Huzhou Radix clematidis floridae Clematis huchouens-is Tamura, herb.Nature and flavor: bitter; Salty; Temperature.Return liver; Urinary bladder channel.Effect: expelling wind and removing dampness; Mass dissipating and swelling eliminating.Anticancer, wind-damp dispelling, removing toxic substances and promoting subsidence of swelling.Cerebroma is controlled in external, deep abscess, rheumatic arthritis.Modern pharmacology is studied, and can be used for treating cerebroma.
Rhizoma Paridis: be the rhizome of liliaceous plant China Rhizoma Paridis Paris chinensis Franch..Nature and flavor: bitter, cold.Slightly poisonous.Effect: heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Epidemic encephalitis type B, stomachache, appendicitis, tuberculous lymphadenitis, tonsillitis, parotitis, mastitis, poisonous snake, insect-bite, sore swollen toxin.
Rhizoma Smilacis Glabrae: be the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..Nature and flavor: sweet, light are flat.Return liver, stomach warp.Effect: removing damp-heat; Let out turbid removing toxic substances; Easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain." book on Chinese herbal medicine justice ": Rhizoma Smilacis Glabrae, dampness removing reduces phlegm and internal heat, and can enter network, searches to pick and damp and hot accumulates poison.It separates hydrargyrum, Calomelas poison person, and it is up that receive poison with ascending, and this leads as business under oozing profit, therefore specially control Fructus Myricae rubrae skin infection, gos deep into hundred networks, arthralgia, even rotten, and poison fire is up again, and throat pain is burst, and all dislike disease.
Side's solution of the present invention is: Rhizoma Pinelliae Preparatum drying dampness to eliminate phlegm, dissolving lump and resolving mass in side, Rhizoma Typhonii wind-damp dispelling, arresting convulsion are jerked, Arisaema Cum Bile, Rhizoma Gastrodiae removing heat-phlegm, dispelling wind and relieving convulsion, Rhizoma Acori Graminei is had one's ideas straightened out eliminating phlegm, refreshment Fructus Alpiniae Oxyphyllae, the above five tastes are monarch drug altogether, fundamentally inducing resuscitation and resolving phlegm is carried out from disease, promote the decomposition of meningioma tumor body, improve brain blood circulation, accelerate the improvement of the state of an illness, carry out dispelling wind and relieving convulsion on the other hand, the modal symptom of meningioma is exactly epilepsy, reduce the attack times of patient's epilepsy from clinical manifestation, thus reach the object of disease therapy.Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving, Fructus Trichosanthis moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Semen Sinapis Albae promoting the circulation of QI eliminating phlegm, path pain relieving, Herba Asari mass dissipating and swelling eliminating, above Six-element is ministerial drug altogether, the effect of have circulation of qi promoting, regulate the flow of vital energy, reducing phlegm, and increases the effect of monarch drug removing heat-phlegm, and get through the blood vessel of intracranial stasis blocking, make normal tissue be moistened foster, reduce the scope of focus further, increase curative effect of medication.Semen Cassiae clearing away heat to improve acuity of vision, the heat clearing away of chrysanthemum powder forimproving wind, suppressing the hyperactive liver improving eyesight, Polyporus, Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, Pseudobulbus Cremastrae Seu Pleiones heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion, Gekko Swinhonis dispelling, collateral-activating, Lignum Sappan blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain, seed of Livistona chinensis R.Br. is anticancer, Herba Clematidis Huchouensis, Rhizoma Paridis expelling wind and removing dampness, mass dissipating and swelling eliminating, Rhizoma Smilacis Glabrae removing damp-heat, a few taste is adjuvant drug altogether above, add dispelling, collateral-activating, the effect of heat-clearing and toxic substances removing, stop the diffusion of tumor cell, reduce the edema of intracranial, alleviate the headache that meningioma brings, the symptoms such as epilepsy, thus reach the effect of disease therapy.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of removing heat-phlegm, dispelling wind and relieving convulsion, eliminating phlegm of having one's ideas straightened out, regulating qi to disperse stagnation, effectively can treat meningioma.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Rhizoma Pinelliae Preparatum 5-15 part, Rhizoma Typhonii 4-14 part, Arisaema Cum Bile 4-14 part, Rhizoma Gastrodiae 7-17 part, Rhizoma Acori Graminei 15-25 part, Radix Curcumae 7-17 part, Fructus Trichosanthis 15-25 part, Pericarpium Citri Reticulatae 7-17 part, Fructus Aurantii Immaturus 7-17 part, Semen Sinapis Albae 4-14 part, Herba Asari 1-5 part, Semen Cassiae 19-29 part, Flos Chrysanthemi 5-15 part, Polyporus 10-20 part, Rhizoma Alismatis 10-20 part, Pseudobulbus Cremastrae Seu Pleiones 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Gekko Swinhonis 7-17 part, Lignum Sappan 4-14 part, seed of Livistona chinensis R.Br. 4-14 part, Herba Clematidis Huchouensis 7-17 part, Rhizoma Paridis 7-17 part, Rhizoma Smilacis Glabrae 13-23 part.
Wherein be preferably: Rhizoma Pinelliae Preparatum 10 parts, Rhizoma Typhonii 9 parts, Arisaema Cum Bile 9 parts, 12 parts, Rhizoma Gastrodiae, Rhizoma Acori Graminei 20 parts, Radix Curcumae 12 parts, Fructus Trichosanthis 20 parts, Pericarpium Citri Reticulatae 12 parts, Fructus Aurantii Immaturus 12 parts, Semen Sinapis Albae 9 parts, Herba Asari 3 parts, Semen Cassiae 24 parts, Flos Chrysanthemi 10 parts, Polyporus 15 parts, Rhizoma Alismatis 15 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Ramulus Uncariae Cum Uncis 15 parts, Gekko Swinhonis 12 parts, Lignum Sappan 9 parts, seed of Livistona chinensis R.Br. 9 parts, Herba Clematidis Huchouensis 12 parts, Rhizoma Paridis 12 parts, Rhizoma Smilacis Glabrae 18 parts.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred preparation method of the present invention is granule, and its preparation method is as follows:
Step one: by weight proportion of the present invention, first becomes medicated bag by Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Sinapis Albae, Semen Cassiae, seed of Livistona chinensis R.Br. bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, grinds to 180 mesh sieves by Rhizoma Pinelliae Preparatum, Arisaema Cum Bile, Polyporus, Gekko Swinhonis, for subsequent use;
Step 3: by weight proportion of the present invention, by Rhizoma Acori Graminei, Radix Curcumae, Rhizoma Paridis, Rhizoma Smilacis Glabrae is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Rhizoma Typhonii is added, Rhizoma Gastrodiae, Rhizoma Alismatis, Pseudobulbus Cremastrae Seu Pleiones, Ramulus Uncariae Cum Uncis, Lignum Sappan, medicated bag in Herba Clematidis Huchouensis and step one decocts about 30 minutes, add Pericarpium Citri Reticulatae afterwards, Herba Asari, Flos Chrysanthemi decocts filtration in 15 minutes, obtain filtrate, merge twice filtrate, filter, waste, merge twice filtrate, and when filtrate being concentrated into about 80 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, for subsequent use,
Step 4: step 2 gained fine powder is added in step 3 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
Medicine removing heat-phlegm of the present invention, dispelling wind and relieving convulsion, effect such as eliminating phlegm, regulating qi to disperse stagnation of having one's ideas straightened out, and it is evident in efficacy, cheap, have no side effect, not easily recur, the mode that this Chinese medicine preparation adopts treats the misery that can reduce chemicotherapy and bring to patient, and decreases the medical expense of the costliness brought of performing the operation, and accelerates the improvement of the state of an illness.According to clinical 200 routine patient view statistics, use specific embodiment of the invention medicine one the total effective rate course for the treatment of 85%, two the total effective rate course for the treatment of 94%.
Detailed description of the invention
Embodiment one, Rhizoma Pinelliae Preparatum 5 parts, Rhizoma Typhonii 4 parts, Arisaema Cum Bile 4 parts, 7 parts, Rhizoma Gastrodiae, Rhizoma Acori Graminei 15 parts, Radix Curcumae 7 parts, Fructus Trichosanthis 15 parts, Pericarpium Citri Reticulatae 7 parts, Fructus Aurantii Immaturus 7 parts, Semen Sinapis Albae 4 parts, Herba Asari 1 part, Semen Cassiae 19 parts, Flos Chrysanthemi 5 parts, Polyporus 10 parts, Rhizoma Alismatis 10 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Ramulus Uncariae Cum Uncis 10 parts, Gekko Swinhonis 7 parts, Lignum Sappan 4 parts, seed of Livistona chinensis R.Br. 4 parts, Herba Clematidis Huchouensis 7 parts, Rhizoma Paridis 7 parts, Rhizoma Smilacis Glabrae 13 parts.
Embodiment two, Rhizoma Pinelliae Preparatum 10 parts, Rhizoma Typhonii 9 parts, Arisaema Cum Bile 9 parts, 12 parts, Rhizoma Gastrodiae, Rhizoma Acori Graminei 20 parts, Radix Curcumae 12 parts, Fructus Trichosanthis 20 parts, Pericarpium Citri Reticulatae 12 parts, Fructus Aurantii Immaturus 12 parts, Semen Sinapis Albae 9 parts, Herba Asari 3 parts, Semen Cassiae 24 parts, Flos Chrysanthemi 10 parts, Polyporus 15 parts, Rhizoma Alismatis 15 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Ramulus Uncariae Cum Uncis 15 parts, Gekko Swinhonis 12 parts, Lignum Sappan 9 parts, seed of Livistona chinensis R.Br. 9 parts, Herba Clematidis Huchouensis 12 parts, Rhizoma Paridis 12 parts, Rhizoma Smilacis Glabrae 18 parts.
Embodiment three, Rhizoma Pinelliae Preparatum 15 parts, Rhizoma Typhonii 14 parts, Arisaema Cum Bile 14 parts, 17 parts, Rhizoma Gastrodiae, Rhizoma Acori Graminei 25 parts, Radix Curcumae 17 parts, Fructus Trichosanthis 25 parts, Pericarpium Citri Reticulatae 17 parts, Fructus Aurantii Immaturus 17 parts, Semen Sinapis Albae 14 parts, Herba Asari 5 parts, Semen Cassiae 29 parts, Flos Chrysanthemi 15 parts, Polyporus 20 parts, Rhizoma Alismatis 20 parts, Pseudobulbus Cremastrae Seu Pleiones 20 parts, Ramulus Uncariae Cum Uncis 20 parts, Gekko Swinhonis 17 parts, Lignum Sappan 14 parts, seed of Livistona chinensis R.Br. 14 parts, Herba Clematidis Huchouensis 17 parts, Rhizoma Paridis 17 parts, Rhizoma Smilacis Glabrae 23 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept patient's totally 200 examples for medical treatment, 46 years old mean age.
Two, Therapeutic Method:
Observation group is according to Medications Example two of the present invention, and the granule that preferred preparation method is made, and boiled water is taken after mixing it with water, every day 3 times, each one bag, within 30 days, is a course for the treatment of.
Three, efficacy assessment standard
1, cure: the relevant symptom of clinical symptoms, sign and tumor disappears completely, follows up a case by regular visits to half a year, does not recur.
2, take a turn for the better: intracranial tumor is controlled, and patient clinical complication reduces gradually, and the symptoms such as headache, epilepsy fade away.
3, do not heal: meningioma and clinical symptoms are without any improvement.
Four, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness in treatment meningioma, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, fourth, female, 68 years old, patient has tinnitus symptom, and it is numb with appearance, walking is unstable, there is the symptom of some epilepsies recently, remove examination in hospital, be diagnosed as meningioma, patient is unwilling to undergo surgery and radiotherapy, determine to adopt expectant treatment, after being introduced, come here to go to a doctor, adopt made granule in the embodiment of the present invention two, after patient takes two courses for the treatment of, sensory symptoms obviously alleviates, tinnitus disappears, facial numbness is alleviated, focus obviously reduces, continue to take two courses for the treatment of, patient's readme symptom alleviates, the mental status is clearly better, remove examination in hospital, tumor regression, there is no diffusing phenomenon, patient continues to take two two courses for the treatment of, until cases of complete remission, follow up a case by regular visits to for many years, have no recurrence, recovery from illness.
Case two, Lee, man, 60 years old, headache, with symptoms such as visual deteriorations, and audition is also much worse than in the past, household does not take notice of always, think it is the natural phenomena that people is old, occur the symptom of walk unstable and slight epilepsy subsequently, patient checks to hospital, be diagnosed as meningioma, carry out surgical resection therapy in hospital, but operation is not clean for tumor complete resection, symptom still exists, carry out chemicotherapy treatment, effect is not clearly, the mental status worse and worse, health is also seriously overdrawed, made granule in the rear employing embodiment of the present invention two, after patient takes three courses for the treatment of, symptom obviously alleviates, the mental status also takes a turn for the better to some extent, epilepsy, headache phenomenon is clearly better, for preventing recurrence, consolidate curative effect, after continuing to take two courses for the treatment of, remove examination in hospital, find that intracranial tumor disappears completely, the state of an illness did not recur again several years, animation also improves gradually, recovery from illness.
Claims (4)
1. treat the Chinese medicine composition of meningioma for one kind, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Rhizoma Pinelliae Preparatum 5-15 part, Rhizoma Typhonii 4-14 part, Arisaema Cum Bile 4-14 part, Rhizoma Gastrodiae 7-17 part, Rhizoma Acori Graminei 15-25 part, Radix Curcumae 7-17 part, Fructus Trichosanthis 15-25 part, Pericarpium Citri Reticulatae 7-17 part, Fructus Aurantii Immaturus 7-17 part, Semen Sinapis Albae 4-14 part, Herba Asari 1-5 part, Semen Cassiae 19-29 part, Flos Chrysanthemi 5-15 part, Polyporus 10-20 part, Rhizoma Alismatis 10-20 part, Pseudobulbus Cremastrae Seu Pleiones 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Gekko Swinhonis 7-17 part, Lignum Sappan 4-14 part, seed of Livistona chinensis R.Br. 4-14 part, Herba Clematidis Huchouensis 7-17 part, Rhizoma Paridis 7-17 part, Rhizoma Smilacis Glabrae 13-23 part.
2. the Chinese medicine composition of the treatment meningioma according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Rhizoma Pinelliae Preparatum 10 parts, Rhizoma Typhonii 9 parts, Arisaema Cum Bile 9 parts, 12 parts, Rhizoma Gastrodiae, Rhizoma Acori Graminei 20 parts, Radix Curcumae 12 parts, Fructus Trichosanthis 20 parts, Pericarpium Citri Reticulatae 12 parts, Fructus Aurantii Immaturus 12 parts, Semen Sinapis Albae 9 parts, Herba Asari 3 parts, Semen Cassiae 24 parts, Flos Chrysanthemi 10 parts, Polyporus 15 parts, Rhizoma Alismatis 15 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Ramulus Uncariae Cum Uncis 15 parts, Gekko Swinhonis 12 parts, Lignum Sappan 9 parts, seed of Livistona chinensis R.Br. 9 parts, Herba Clematidis Huchouensis 12 parts, Rhizoma Paridis 12 parts, Rhizoma Smilacis Glabrae 18 parts.
3. the Chinese medicine preparation for the treatment of meningioma according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is granule.
4. treat a preparation method for the Chinese medicine preparation of meningioma, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, first Fructus Trichosanthis, Fructus Aurantii Immaturus, Semen Sinapis Albae, Semen Cassiae, seed of Livistona chinensis R.Br. bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use, step 2: by weight proportion of the present invention, grinds to 180 mesh sieves by Rhizoma Pinelliae Preparatum, Arisaema Cum Bile, Polyporus, Gekko Swinhonis, for subsequent use, step 3: by weight proportion of the present invention, by Rhizoma Acori Graminei, Radix Curcumae, Rhizoma Paridis, Rhizoma Smilacis Glabrae is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Rhizoma Typhonii is added, Rhizoma Gastrodiae, Rhizoma Alismatis, Pseudobulbus Cremastrae Seu Pleiones, Ramulus Uncariae Cum Uncis, Lignum Sappan, medicated bag in Herba Clematidis Huchouensis and step one decocts about 30 minutes, add Pericarpium Citri Reticulatae afterwards, Herba Asari, Flos Chrysanthemi decocts filtration in 15 minutes, obtain filtrate, merge twice filtrate, filter, waste, merge twice filtrate, and when filtrate being concentrated into about 80 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, for subsequent use, step 4: step 2 gained fine powder is added in step 3 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100818205B1 (en) * | 2006-07-22 | 2008-03-31 | 한서제약 주식회사 | Compositions for Treating or Preventing Cancer Comprising Extracts from Magnolia Plant as an Active Ingredient |
| CN101979076A (en) * | 2010-11-04 | 2011-02-23 | 江苏省中医院 | Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof |
-
2015
- 2015-03-12 CN CN201510108100.0A patent/CN104645243A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100818205B1 (en) * | 2006-07-22 | 2008-03-31 | 한서제약 주식회사 | Compositions for Treating or Preventing Cancer Comprising Extracts from Magnolia Plant as an Active Ingredient |
| CN101979076A (en) * | 2010-11-04 | 2011-02-23 | 江苏省中医院 | Compound combination medicament for treating cerebral metastatic tumor and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 许沛虎: "《中医脑病学》", 30 September 1998 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620536A (en) * | 2017-01-24 | 2017-05-10 | 栾雷 | Formula of traditional Chinese medicine for treating meningioma |
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