CN104644977A - Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof - Google Patents
Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof Download PDFInfo
- Publication number
- CN104644977A CN104644977A CN201510104999.9A CN201510104999A CN104644977A CN 104644977 A CN104644977 A CN 104644977A CN 201510104999 A CN201510104999 A CN 201510104999A CN 104644977 A CN104644977 A CN 104644977A
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- radix
- nasopharyngeal carcinoma
- subsequent use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma. The preparation is prepared from the following raw materials in parts by weight: 15-20 parts of mongolian snake gourd root, 9-16 parts of dandelion, 10-15 parts of radix cynanchi bungei, 8-15 parts of sunflower seed, 9-16 parts of pangolin, 15-20 parts of loofah sponge, 15-20 parts of radix clematidis, 15-20 parts of fructus forsythia, 10-15 parts of manyleaf paris rhizome,10-15 parts of poria cocos, 15-20 parts of periostracum cicada, 6-10 parts of seeds of garden balsam, 8-12 parts of tangerine leaves, 15-25 parts of astragalus membranaceus and 5-10 parts of ciliatenerve knotweed roots. The preparation has excellent effects that the Chinese herbal medicines are capable of effectively relieving the state of illness and controlling cancer cells; and through systemic therapy on nasopharyngeal carcinoma, patients reach a recovery state. The preparation is developed by combining the latest modern scientific achievements with the traditional Chinese medicine treatment based on symptom differentiation, and based on the effects of all the medicinal materials, the preparation is significant in curative effect, safe, convenient and low in price.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation and preparation method.
Background technology
Nasopharyngeal carcinoma (Nasopharyngeal carcinoma, NPC) refers to the malignant tumor betiding cavum nasopharyngeum top and sidewall.Be one of China's malignant tumor occurred frequently, sickness rate is first of ear,nose & throat malignant tumor.Common symptoms is for being with blood, ear suffocation sense, auditory dysesthesia, diplopia and headache etc. in nasal obstruction, tears.Nasopharyngeal carcinoma is a kind of tumor having characteristic, betides nasopharyngeal mucosa, and the areas such as China Guangdong, Guangxi, Fujian, Hunan are multiple districts, and the cause of disease is relevant with factors such as inherited genetic factors, Epstein-Barr virus and environment.Nasopharyngeal carcinoma grade malignancy is higher, and site of pathological change is hidden, and early stage nasopharyngeal carcinoma symptom is not obvious, can occur metastasic cervical lymph nodes.Current primary treatments has the Therapeutic Method such as radiotherapy, chemotherapy, operation, Chinese medicine and gene therapy.
Although not to the direct record of nasopharyngeal carcinoma in Chinese Ancient Books, but nasopharyngeal carcinoma can be belonged to the category such as " cervical carcinoma with cachexia ", " stony mass behind the ear " of Chinese medicine, " grandular plague " " nasal sinusitis ", ancient medicine recognizes that mostly the reason that nasopharyngeal carcinoma occurs is that wherein fire-toxin expectorant base " void " is the key of its pathogenesis caused by healthy energy virtual loss, pathogenic fire derived from stagnation of liver-QI, knot expectorant, raw addiction.
Publication number CN 101530461 A(application number 200810101836.5) Chinese invention patent document disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, be prepared from by the raw material of following weight ratio: Oletum Trogopterori 0.3-2.5 part; Resina Toxicodendri 0.15-1.2 part; Radix Notoginseng 0.4-3 part; Herba Selaginellae Doederleinii 0.3-2.5 part; Ganoderma 0.4-3 part; Radix Sophorae Tonkinensis 0.4-3.2 part; Radix Angelicae Sinensis 0.5-4.2 part; Rhizoma Bolbostematis 0.4-3.2 part, Scolopendra 0.2-1.8 part.Application publication number CN 103845613 A(application number 201210532689.3) Chinese invention patent document disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, be made up of the component of following weight portion: Herba Solani Nigri 20-40 gram, Radix Sophorae Tonkinensis 15-25 gram, Pseudobulbus Cremastrae Seu Pleiones 15-25 gram.Authorization Notice No. CN 103071112 A(application number 201310001820.8) Chinese invention patent document disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, the weight proportion of each raw material components is: Radix vitis romanetii 8-12, Fructus Aurantii Immaturus 13-17, Fructus Akebiae 28-32, Radix Ginseng 4-15, Rhizoma Gymnadeniae 4-15, Rhizoma Coptidis 13-17, Oletum Trogopterori 8-12, Herba Duchesneae Indicae 28-32, little red Bulbus Allii root 8-12, Rhizoma Chuanxiong 13-17, Rhizoma Sparganii 4-15, Rhizoma Curcumae 13-17, huechys 28-32, Radix Aristolochiae Kaempferi 4-15, Herba Artemisiae Anomalae 8-12, Radix Tinosporae 28-32, Herba Houttuyniae 1-5, Radix seu folium abelmoschi moschati 8-12, Aster oreophilus Franch 4-15, Herba Catharanthi Rosei 1-5, Nidus Vespae 28-32, Herba Polygoni cymosi 13-17.
The simple western medicine treatment of nasopharyngeal carcinoma has very high relapse rate and complication, Traditional Chinese Medicine Chinese medicine utilizes organic conception opinion to control and achieve certain curative effect in the treatment of nasopharyngeal carcinoma, by means such as reinforcing righting, detoxicating and fighting cancers, decrease recurrence to a certain extent, alleviate symptom, improve life quality.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide that one is prepared simply, taking convenience, safely and effectively a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation and preparation method.Curative effect of medication of the present invention is remarkable and without any side effects, is convenient to clinical practice.
Technical scheme of the present invention is:
A kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion: Radix Trichosanthis 15-20; Herba Taraxaci 9-16; Radix Cynanchi Auriculati 10-15; Semen Helianthi 8-15; Squama Manis 9-16; Retinervus Luffae Fructus 15-20; Radix Clematidis 15-20; Fructus Forsythiae 15-20; Rhizoma Paridis 10-15; Poria 10-15; Periostracum Cicadae 15-20; Semen Impatientis 6-10; Folium Citri tangerinae 8-12; Radix Astragali 15-25; Radix Aristolochiae Kaempferi 5-10.
In preferred scheme, Radix Trichosanthis 16-19; Herba Taraxaci 11-14; Radix Cynanchi Auriculati 11-14; Semen Helianthi 10-13; Squama Manis 11-14; Retinervus Luffae Fructus 16-19; Radix Clematidis 16-19; Fructus Forsythiae 16-19; Rhizoma Paridis 11-14; Poria 11-14; Periostracum Cicadae 16-19; Semen Impatientis 7-9; Folium Citri tangerinae 9-11; Radix Astragali 17-23; Radix Aristolochiae Kaempferi 6-9.
Be more preferably, Radix Trichosanthis 17.5; Herba Taraxaci 12.5; Radix Cynanchi Auriculati 12.5; Semen Helianthi 11.5; Squama Manis 12.5; Retinervus Luffae Fructus 17.5; Radix Clematidis 17.5; Fructus Forsythiae 17.5; Rhizoma Paridis 12.5; Poria 12.5; Periostracum Cicadae 17.5; Semen Impatientis 8; Folium Citri tangerinae 10; The Radix Astragali 15; Radix Aristolochiae Kaempferi 7.5.
A kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, be made into pharmaceutically acceptable decoction, preparation method is as follows:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, sieves for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) by dry to Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae 3-6 hour, take out, grind powdered, for subsequent use;
(3) by step (1) and step (2) gained raw material medicated powder, penetrating bag is placed in, sealing, for subsequent use;
(4) crude drug except Squama Manis, Retinervus Luffae Fructus, Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae is together placed in Chinese medicine extracting tank, the clear water adding 4-9 times amount soaks 2-5 hour (clear water preferably adding 6.5 times amount soaks 3.5 hours), then step (3) gained raw material medicated powder is added, intense fire heated and boiled, turn slow fire boiling twice, first time decocts 40-50 minute (preferably first time decocts 45 minutes), second time decocts 20-30 minute (preferably second time decocts 25 minutes), filter, merge twice decocting liquid;
(5) step (4) gained medicinal residues are continued the clear water adding 3.5 times amount, slow fire boiling 10-20 minute (preferably slow fire boiling 15 minutes), filter, filtrate and above-mentioned decocting liquid merge, and continue heating and be concentrated into original liquid volume 1/2, sterilizing, encapsulation, to obtain final product.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction, preferred scheme is, the middle 50-90 mesh sieve excessively of step (1) (preferred 60-80 mesh sieve excessively, mistake 70 mesh sieve be more preferably).
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction, preferred scheme is, temperature dry in step (2) is 43-77 DEG C (preferred dry temperature is 55-65 DEG C, and the temperature of the drying be more preferably is 60 DEG C).
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction, preferred scheme is, in step (2) dry 4-5 hour (preferably dry 4.5 hours).
The preparation method of described pill is:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, crosses 60 mesh sieves, for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) crude drug except Squama Manis and Retinervus Luffae Fructus is placed in thermostatic drying chamber, in 53-77 DEG C of freeze-day with constant temperature 3.5-6.5 hour (being preferable over 65 DEG C of freeze-day with constant temperature 5 hours), take out, being placed in pulverizer, to be ground into fine powder for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, with the general ball of alcohol, make the pill of Semen Firmianae size, to obtain final product.
The preparation method of described granule is:
(1) Squama Manis, Semen Impatientis and Periostracum Cicadae are placed in medicine pot respectively, slow fire heating is dried, and then smashs into fine powder to pieces, for subsequent use;
(2) Radix Trichosanthis, Radix Clematidis, Retinervus Luffae Fructus, Radix Cynanchi Auriculati, Fructus Forsythiae, the Radix Astragali and Radix Aristolochiae Kaempferi are together placed in 77 DEG C of drying baker, freeze-day with constant temperature 20-40 minute (preferred freeze-day with constant temperature 25 minutes), take out, smash into fine powder to pieces, for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, 70-90 mesh sieve (preferred mistake 80 mesh sieve) is crossed, for subsequent use;
(4) Herba Taraxaci, Semen Helianthi, Rhizoma Paridis, Poria and Folium Citri tangerinae are together placed in medicinal cupping, add clear water and do not have powder, slow fire boiling twice, each respectively decoction 25-35 minute (preferably each each decoction 30 minutes), filter, collecting decoction, it is the thick paste of 1.18-1.20 that decocting liquid continues to be evaporated to 70 DEG C of relative densities, for subsequent use;
(5) joined in above-mentioned thick paste by step (3) gained mixing fine powders, stir, then add dextrin fine powder and corn starch (thick paste powder: Bidismutose: amylum pregelatinisatum=6:1.5:1.1), granulate, cross No. six sieves, subpackage, to obtain final product.
The preparation method of described powder is:
(1) all crude drug are together placed in Chinese medicine air drier, in 70-90 DEG C of dry 2-3 hour (being preferable over 80 DEG C of dryings 2.5 hours), taking out, be ground into fine powder, for subsequent use;
(2) by above-mentioned raw materials medicated powder mix homogeneously, cross 60-120 mesh sieve (preferred mistake 90 mesh sieve), be encapsulated into bag, every bag of 20-30g(preferably every bag of 25g), to obtain final product.
Scientific formula of the present invention, preparation method is simple, taking convenience, Be very effective.In addition, excellent results of the present invention also shows:
1,the effective mitigate the disease of Chinese herbal medicine energy, controls cancerous cell, by the whole body therapeutic to nasopharyngeal carcinoma, makes patient reach rehabilitation state;
2,proportioning science of the present invention, has replenishing YIN and removing heat, dispersing swelling and dissipating binds, the effects such as loose wind sore-throat relieving, loose blood and relieving pain;
3,the present invention develops in conjunction with latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment, and all medicines share, and has evident in efficacy, safe ready, cheap feature.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion (65g/ part): Radix Trichosanthis 15 parts; Herba Taraxaci 9 parts; Radix Cynanchi Auriculati 10 parts; Semen Helianthi 8 parts; Squama Manis 9 parts; Retinervus Luffae Fructus 15 parts; Radix Clematidis 15 parts; Fructus Forsythiae 15 parts; Rhizoma Paridis 10 parts; 10 parts, Poria; Periostracum Cicadae 15 parts; Semen Impatientis 6 parts; Folium Citri tangerinae 8 parts; The Radix Astragali 15 parts; Radix Aristolochiae Kaempferi 5 parts.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction is:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, crosses 50 mesh sieves, for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) by Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae in 43 DEG C of dryings 3 hours, take out, grind powdered, for subsequent use;
(3) by step (1) and step (2) gained raw material medicated powder, penetrating bag is placed in, sealing, for subsequent use;
(4) crude drug except Squama Manis, Retinervus Luffae Fructus, Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae is together placed in Chinese medicine extracting tank, the clear water adding 4 times amount soaks 2 hours, then step (3) gained raw material medicated powder is added, intense fire heated and boiled, turn slow fire boiling twice, first time decocts 40 minutes, and second time decocts 20 minutes, filter, merge twice decocting liquid;
(5) step (4) gained medicinal residues are continued the clear water adding 3.5 times amount, slow fire boiling 10 minutes, filter, filtrate and above-mentioned decocting liquid merge, and continue heating and be concentrated into original liquid volume 1/2, sterilizing, encapsulation, to obtain final product.
The instructions of taking of decoction of the present invention is: once a day, each 200-250mL, warmly takes, and within 30 days, is a course for the treatment of.
Model case: Du XX, man, 53 years old, people from Heze.Patient is to our hospital in JIUYUE in 2011 19 days.Mr. Du made a definite diagnosis at local hospital before 1 year suffers from nasopharyngeal carcinoma, accepts chemotherapeutic treatment subsequently, after four courses for the treatment of of chemotherapy, the health of Mr. Du becomes extremely feeble, oral cavity severe ulceration can not be taken food, and other symptoms of health are not also clearly better, and carrys out my institute's treatment afterwards upon somebody's introduction.Check: patient's nasal bleeding, with dizzy, headache, tinnitus symptom, patient's figure is become thin, weak.Have obvious lump through CT examination patient nasopharynx part, in conjunction with other lab testings, nasopharyngeal carcinoma is made a definite diagnosis errorless.
Taking a kind of nasopharyngeal carcinoma replenishing YIN and removing heat of the present embodiment gained decoction, instructions of taking: once a day, each 200-250mL, warmly to take, 30 days is a course for the treatment of.After treating a course for the treatment of, the transference cures such as patient's dizziness, headache, patient mental recovers gradually; Two courses for the treatment of of continual cure, find that nasopharynx part lump disappears, Rehabilitation through CT examination, exhort that continuing medication is consolidated a course for the treatment of, follow up a case by regular visits to after half a year, patient body is healthy, without recurrence.
embodiment 2a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion (45g/ part): Radix Trichosanthis 20 parts; Herba Taraxaci 16 parts; Radix Cynanchi Auriculati 15 parts; Semen Helianthi 15 parts; Squama Manis 16 parts; Retinervus Luffae Fructus 20 parts; Radix Clematidis 20 parts; Fructus Forsythiae 20 parts; Rhizoma Paridis 15 parts; 15 parts, Poria; Periostracum Cicadae 20 parts; Semen Impatientis 10 parts; Folium Citri tangerinae 12 parts; The Radix Astragali 25 parts; Radix Aristolochiae Kaempferi 10 parts.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat pill is:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, crosses 60 mesh sieves, for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) crude drug except Squama Manis and Retinervus Luffae Fructus is placed in thermostatic drying chamber, in 65 DEG C of freeze-day with constant temperature 5 hours, takes out, being placed in pulverizer, to be ground into fine powder for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, with the general ball of alcohol, make the pill of Semen Firmianae size, to obtain final product.
The instructions of taking of pill of the present invention is: every day three times, each 10-12 ball (considering plus-minus according to conditions of patients), and warm water takes, 30 days courses for the treatment of.
embodiment 3a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion (60g/ part): Radix Trichosanthis 16 parts; Herba Taraxaci 11 parts; Radix Cynanchi Auriculati 11 parts; Semen Helianthi 10 parts; Squama Manis 11 parts; Retinervus Luffae Fructus 16 parts; Radix Clematidis 16 parts; Fructus Forsythiae 16 parts; Rhizoma Paridis 11 parts; 11 parts, Poria; Periostracum Cicadae 16 parts; Semen Impatientis 7 parts; Folium Citri tangerinae 9 parts; The Radix Astragali 17 parts; Radix Aristolochiae Kaempferi 6 parts.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat granule is:
(1) Squama Manis, Semen Impatientis and Periostracum Cicadae are placed in medicine pot respectively, slow fire heating is dried, and then smashs into fine powder to pieces, for subsequent use;
(2) Radix Trichosanthis, Radix Clematidis, Retinervus Luffae Fructus, Radix Cynanchi Auriculati, Fructus Forsythiae, the Radix Astragali and Radix Aristolochiae Kaempferi are together placed in 77 DEG C of drying baker, freeze-day with constant temperature 25 minutes, take out, smash into fine powder to pieces, for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, 80 mesh sieves are crossed, for subsequent use;
(4) Herba Taraxaci, Semen Helianthi, Rhizoma Paridis, Poria and Folium Citri tangerinae are together placed in medicinal cupping, add clear water and do not have powder, slow fire boiling twice, each each decoction 30 minutes, filters, collecting decoction, it is the thick paste of 1.18-1.20 that decocting liquid continues to be evaporated to 70 DEG C of relative densities, for subsequent use;
(5) joined in above-mentioned thick paste by step (3) gained mixing fine powders, stir, then add dextrin fine powder and corn starch (thick paste powder: Bidismutose: amylum pregelatinisatum=6:1.5:1.1), granulate, cross No. six sieves, subpackage, to obtain final product.
The instructions of taking of granule of the present invention is: every day three times, each 15-20g(considers plus-minus according to conditions of patients), warm water is taken after mixing it with water, 30 days courses for the treatment of.
embodiment 4a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion (50g/ part): Radix Trichosanthis 19 parts; Herba Taraxaci 14 parts; Radix Cynanchi Auriculati 14 parts; Semen Helianthi 13 parts; Squama Manis 14 parts; Retinervus Luffae Fructus 19 parts; Radix Clematidis 19 parts; Fructus Forsythiae 19 parts; Rhizoma Paridis 14 parts; 14 parts, Poria; Periostracum Cicadae 19 parts; Semen Impatientis 9 parts; Folium Citri tangerinae 11 parts; The Radix Astragali 23 parts; Radix Aristolochiae Kaempferi 9 parts.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat powder is:
(1) all crude drug are together placed in Chinese medicine air drier, in 80 DEG C of dryings 2.5 hours, take out, be ground into fine powder, for subsequent use;
(2) by above-mentioned raw materials medicated powder mix homogeneously, cross 90 mesh sieves, be encapsulated into bag, every bag of 25g, to obtain final product.
The instructions of taking of powder of the present invention is: twice daily, each 1-2 bag (considering plus-minus according to the state of an illness), and hot water is taken after mixing it with water, 30 days courses for the treatment of.
Model case: grandson XX, man, 50 years old, people from Tai'an.Patient is to our hospital on June 22nd, 2012.Patient 3 months cause nasal obstruction, nasal mucus band blood, dizziness headache symptom is treated at local hospital.Be diagnosed as nasopharyngeal carcinoma early stage.Carry out chemotherapy subsequently, for the first time after end of chemotherapy, patient has a stuffy nose, nasal mucus band blood situation is alleviated, but checks discovery nasopharyngeal carcinoma lymph metastasis soon, and doctor advised carries out radiotherapy again, families of patients thinks that chemotherapy risk is too large, abandons chemotherapy, determines to attempt Chinese traditional treatment.Made some inquiries about afterwards, patient comes my institute and checks treatment.Check: the chemotherapy side effects such as patient's spiritedness is dispirited, headache, stomach discomfort, are diagnosed as nasopharyngeal carcinoma through CT examination.
Take a kind of nasopharyngeal carcinoma replenishing YIN and removing heat of the present embodiment gained powder, instructions of taking: twice daily, each 1-2 bag, hot water is taken after mixing it with water, 30 days courses for the treatment of.After treating a course for the treatment of, patient's nasal obstruction, nasal mucus band mass formed by blood stasis shape obviously alleviate, and spirit is clearly better, headache, stomach discomfort transference cure; Two courses for the treatment of of continual cure, patient clinical symptom and sign all disappear, and CT examination lump disappears, and does not have new tumor to produce, and patient fully recovers, and advise a course for the treatment of of continual cure with consolidate curative effect, follow up a case by regular visits to after half a year, patient body in order, without recurring.
embodiment 5a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is prepared from by following bulk drugs, is weight portion (55g/ part): Radix Trichosanthis 17.5 parts; Herba Taraxaci 12.5 parts; Radix Cynanchi Auriculati 12.5 parts; Semen Helianthi 11.5 parts; Squama Manis 12.5 parts; Retinervus Luffae Fructus 17.5 parts; Radix Clematidis 17.5 parts; Fructus Forsythiae 17.5 parts; Rhizoma Paridis 12.5 parts; 12.5 parts, Poria; Periostracum Cicadae 17.5 parts; Semen Impatientis 8 parts; Folium Citri tangerinae 10 parts; The Radix Astragali 15 parts; Radix Aristolochiae Kaempferi 7.5 parts.
The preparation method of above-mentioned a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction is:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, crosses 70 mesh sieves, for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) by Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae in 60 DEG C of dryings 4.5 hours, take out, grind powdered, for subsequent use;
(3) by step (1) and step (2) gained raw material medicated powder, penetrating bag is placed in, sealing, for subsequent use;
(4) crude drug except Squama Manis, Retinervus Luffae Fructus, Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae is together placed in Chinese medicine extracting tank, the clear water adding 6.5 times amount soaks 3.5 hours, then step (3) gained raw material medicated powder is added, intense fire heated and boiled, turn slow fire boiling twice, first time decocts 45 minutes, and second time decocts 25 minutes, filter, merge twice decocting liquid;
(5) step (4) gained medicinal residues are continued the clear water adding 3.5 times amount, slow fire boiling 15 minutes, filter, filtrate and above-mentioned decocting liquid merge, and continue heating and be concentrated into original liquid volume 1/2, sterilizing, encapsulation, to obtain final product.
The instructions of taking of decoction of the present invention is: once a day, each 200-250mL, warmly takes, and within 30 days, is a course for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Trichosanthis: base is former: be the root of cucurbitaceous plant Fructus Trichosanthis.Nature and flavor: sweetness and bitterness acid are cool.Gui Jing: enter lung, stomach warp.Function cures mainly: promote the production of body fluid, and quenches the thirst, and pathogenic fire reducing is moisturized, evacuation of pus, detumescence.Control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula.
Herba Taraxaci: base is former: be the whole herb with root of feverfew Herba Taraxaci.Chemical analysis: Herba Taraxaci herb is containing taraxasterol, choline, inulin and pectin etc.Nature and flavor: bitter sweet, cold.Gui Jing: enter liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Radix Cynanchi Auriculati: base is former: be the tuber of asclepiadaceae plant Cynanchum bungei Decne.Chemical analysis: Cynanchum bungei Decne, containing cynanchol, has cardiotonic glycoside to react.Nature and flavor: " Shandong Chinese medicine ": " bitter but sweet flavor is puckery, and property is micro-prevents, nontoxic." function cures mainly: " Shandong Chinese medicine ": " for nourishing, strong, hematonic, and can restrain vital essence, crow must hair color.Control prolonged illness weakness, anemia, early whitening of beard and hair, chronic migratory arthralgia, soreness of the waist and knees, sexual neurasthenie, hemorrhoid, enterorrhagia, deficiency of YIN chronic malaria, ulcer does not close up for a long time.Fresh and have the effect of loosening bowel to relieve constipation, be applicable to old people constipation.”
Semen Helianthi: base is former: be the seed of feverfew Helianthi.Chemical analysis: the fatty oil of seed reaches about 50%, in have volume linoleic acid to reach 70%, along having phospholipid, the sterols such as Sitosterolum.Pharmacological action: 1, effect for reducing blood fat; 2, immunization is strengthened.Nature and flavor: sweet in the mouth; Property is put down.Function cures mainly: control dysentery, saturating pus of carbuncle.
Squama Manis: base is former: be the scute of Manidae animal Squama Manis.Nature and flavor: salty, cool, be slightly cold.Gui Jing; Return liver, stomach warp.Cure mainly: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Retinervus Luffae Fructus: base is former: be the reticular fiber of the old hot fruit of cucurbitaceous plant Fructus Luffae or the withered old fruit of Guangdong Fructus Luffae.Sweet in the mouth is flat.Return lung, stomach, Liver Channel.Main chemical compositions is xylan and cellulose, also may contain mannan, galactan and lignin etc.The particular matters such as the saponins in the middle of Fructus Luffae, luffein, lymphatic temperament, wood glue, citrulline, xylan and interferon have certain special role.Contained by prevent the vitamin B1 of skin aging, the compositions such as the vitamin C of skin whitening, can protect skin, eliminate speckle, making skin pure white, delicate, is rare cosmetic good merchantable brand, therefore Sucus Luffae has the title of " beauty's water ".Have that dysmenorrhea is active, effect of removing heat-phlegm.Control pain in chest and hypochondrium, stomachache, lumbago, lung-heat productive cough, carbuncle, anal fistula.
Radix Clematidis: base is former: be the root of cohosh Radix Clematidis.Chemical analysis: 1. the root of Radix Clematidis is containing Anemonin, anemonol, sterol, saccharide, Saponin, lactone, phenols, aminoacid.Leaf is containing lactone, phenols, triterpene, aminoacid, organic acid.Pharmacological action: 1. to the effect of blood circulation; 2. on the impact of smooth muscle; 3. antidiuretic activity; 4. hypoglycemic activity.Nature and flavor: Xin Xian, temperature, poisonous.Gui Jing: enter urinary bladder channel.Function cures mainly: wind-damp dispelling, the meridian dredging, expectorant saliva, the loose hypochondriac lump.Control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Fructus Forsythiae: base is former: this product is the dry fruit of Oleaceae plants Fructus Forsythiae.Character: this product is in long avette to avette, slightly flat.There is the fleck of irregular vertical wrinkle and most projection on surface, and respectively there is 1 obvious longitudinal furrow on two sides.The sharp point in top.Nature and flavor: bitter, are slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly: for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Rhizoma Paridis: base is former: be the rhizome of liliaceous plant Rhizoma Paridis.Chemical analysis: Rhizoma Paridis root is containing paridin, dioscin, and the 3-glycoside of diosgenin, 3-scillabiose, 3-rhamnose arabinose glycoside and 3-tetra-glucoside, the diene alcohol ketone-3-that is pregnent investigates the multiple Saponins such as solatriose glycoside.Pharmacological action: 1. to relieving asthma, antitussive action, 2. antibacterial action.Nature and flavor: toil, cold, poisonous.Gui Jing: enter the heart, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, antiasthmatic-antitussive, and relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion is twitched, snake bite and insect sting.
Poria: base is former: this product is the dry sclerotia of On Polyporaceae Poria.Character: Poria spherical, oval in class, an oblate or irregular agglomerate, not of uniform size.Crust is thin and coarse, and sepia, to pitchy, has obvious shrinkage texture.Nature and flavor: sweet, light are flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Cure mainly: for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Periostracum Cicadae: base is former: exuviae shell when this product is the nymph emergence of cicada Cryptotympana atrata Fabr..Pharmacological action: 1, anticonvulsant action; 2, sedation; 3, Periostracum Cicadae decoct can block the conduction of cat Superior cervical sympathetic ganglia, on adrenoreceptor and acetylcholine nerve depressor response then without impact.Nature and flavor: sweet, cold.Gui Jing: return lung, Liver Channel.Effect: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.Cure mainly: for anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion buckwheat hinders, convulsion with spasms, tetanus.
Semen Impatientis: base is former: be the seed of Balsaminaceae plant Impatientis.Chemical analysis: containing balsaminasterol, Parinaric Acid, Saponin, fatty oil, polysaccharide, protein, aminoacid, volatile oil, and the flavonoid such as the polysaccharid glucoside of Quercetin and the derivant of nimbecetin.Nature and flavor: toil, temperature, poisonous.Gui Jing: 1. " beautiful Chinese catalpa medicine solution ": " enter kidney meridian."; 2. " book on Chinese herbal medicine is new again ": " enter liver, lung two warp." function cures mainly: removing blood stasis, removing food stagnancy, softening the hard mass.Control amenorrhea, long-pending block, dysphagic, outer infections heavily fortified point is swollen, a fishbone or other bone caught in the throat not under.
Folium Citri tangerinae: source: be the leaf of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.Character: dried leaves multireel contracts, in Pedicellus et Pericarpium Trapae shape oblong or ellipse after open and flat, surperficial celadon or yellow green, smooth, can according to seeing numerous transparent glandule points to light.Nature and flavor: toil are flat.Gui Jing: Zhu Zhenheng: " enter liver channel of foot-Jueyin edema caused by disorder of QI." function cures mainly: soothing the liver, circulation of qi promoting, reduces phlegm, detumescence poison.Control hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.
The Radix Astragali: base is former: this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Nature and flavor: sweet, temperature.Gui Jing: return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cure mainly: weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Aristolochiae Kaempferi: base is former: be the tuber of aristolochiaceae plant Aristolochia koempeferi.Chemical analysis: seed is containing Aristolochic Acid, magnoflorine, rotation rattan phenol alkali and asimilobine.Nature and flavor: bitter in the mouth is pungent, cold in nature, nontoxic.Gui Jing: enter the heart, lung, Liver Channel.Function cures mainly: detumescence of relieving inflammation or internal heat, and loose blood and relieving pain, antidotes against snake bite.Control red-white dysentery, breast, abdomen, laryngalgia, venom.
test example 1the clinical practice of a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation (embodiment 5) of gained of the present invention:
1 data and method
1.1 physical data
In November ,-2013 in March, 2010, screen 296 routine Nasopharyngeal Carcinoma Patients in 4 hospitals, wherein male 173 example, women 123 example; In all patients oldest 61 years old, minimum 29 years old, 52 years old mean age.All patients all make a definite diagnosis through histopathology and CT examination.
1.2 Therapeutic Method
All patients are divided into treatment group and matched group at random, and two groups of patients, in the state of an illness, the course of disease etc., through statistical procedures no significant difference (P > 0.05), have comparability.Wherein treatment group takes gained medicine of the present invention, observes three courses for the treatment of of treatment altogether.Matched group uses other drug (as chemotherapeutics such as cyclophosphamide, bleomycin A5 and 5-fluorouracil).
1.3 curative effect determinate standard
According to the relevant criterion in " new Chinese medicine guideline of clinical investigations ".
Clinical cure: the clinical symptoms of patient and sign disappear completely and continue more than one month; Effective: clinical symptoms and sign partial disappearance or obviously alleviate, mass reduction is over half, and continues more than one month; Effective: clinical symptoms and sign alleviate to some extent, and mass reduction is less than 50%; Invalid: unchanged or aggravation after treatment.
1.4 therapeutic outcome
Table 1: take embodiment 5 product radiotherapy in patients with nasopharyngeal carcinoma result
Therapeutic effect: clinical cure 107 example (59.4%), effective 52 examples (29%), effective 17 examples (9.4%), invalid 4 examples (2.2%), total effective rate 97.8%.Treatment group successful is better than matched group.
The present invention select Radix Trichosanthis, Herba Taraxaci, Radix Cynanchi Auriculati, Semen Helianthi, Squama Manis, Retinervus Luffae Fructus, Radix Clematidis, Fructus Forsythiae, Rhizoma Paridis, Poria, Periostracum Cicadae, Semen Impatientis, Folium Citri tangerinae, the Radix Astragali and Radix Aristolochiae Kaempferi totally 15 taste crude drug be prepared from.For compositions of the present invention, according to the prescription compatibility theory of " monarch, minister, help, make ", Radix Trichosanthis, Retinervus Luffae Fructus, Radix Clematidis, Fructus Forsythiae, Periostracum Cicadae and the Radix Astragali are monarch drug; Herba Taraxaci, Radix Cynanchi Auriculati, Semen Helianthi, Rhizoma Paridis, Squama Manis and Poria are ministerial drug; Folium Citri tangerinae is adjuvant drug; Semen Impatientis and Radix Aristolochiae Kaempferi are for making medicine.Said medicine supplements and complements each other, and supports mutually, and achieves through clinical trial and be satisfied with technique effect.After treating three courses for the treatment of, treatment group total effective rate is 97.8%, and matched group is only 72.4%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. a nasopharyngeal carcinoma replenishing YIN and removing heat preparation, is characterized in that, is prepared from by following bulk drugs, is weight portion: Radix Trichosanthis 15-20; Herba Taraxaci 9-16; Radix Cynanchi Auriculati 10-15; Semen Helianthi 8-15; Squama Manis 9-16; Retinervus Luffae Fructus 15-20; Radix Clematidis 15-20; Fructus Forsythiae 15-20; Rhizoma Paridis 10-15; Poria 10-15; Periostracum Cicadae 15-20; Semen Impatientis 6-10; Folium Citri tangerinae 8-12; Radix Astragali 15-25; Radix Aristolochiae Kaempferi 5-10.
2. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Trichosanthis 16-19; Herba Taraxaci 11-14; Radix Cynanchi Auriculati 11-14; Semen Helianthi 10-13; Squama Manis 11-14; Retinervus Luffae Fructus 16-19; Radix Clematidis 16-19; Fructus Forsythiae 16-19; Rhizoma Paridis 11-14; Poria 11-14; Periostracum Cicadae 16-19; Semen Impatientis 7-9; Folium Citri tangerinae 9-11; Radix Astragali 17-23; Radix Aristolochiae Kaempferi 6-9.
3. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Trichosanthis 17.5; Herba Taraxaci 12.5; Radix Cynanchi Auriculati 12.5; Semen Helianthi 11.5; Squama Manis 12.5; Retinervus Luffae Fructus 17.5; Radix Clematidis 17.5; Fructus Forsythiae 17.5; Rhizoma Paridis 12.5; Poria 12.5; Periostracum Cicadae 17.5; Semen Impatientis 8; Folium Citri tangerinae 10; The Radix Astragali 15; Radix Aristolochiae Kaempferi 7.5.
4. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable decoction, preparation method is as follows:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, sieves for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) by dry to Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae 3-6 hour, take out, grind powdered, for subsequent use;
(3) by step (1) and step (2) gained raw material medicated powder, penetrating bag is placed in, sealing, for subsequent use;
(4) crude drug except Squama Manis, Retinervus Luffae Fructus, Fructus Forsythiae, Periostracum Cicadae, Semen Impatientis and Folium Citri tangerinae is together placed in Chinese medicine extracting tank, the clear water adding 4-9 times amount soaks 2-5 hour (clear water preferably adding 6.5 times amount soaks 3.5 hours), then step (3) gained raw material medicated powder is added, intense fire heated and boiled, turn slow fire boiling twice, first time decocts 40-50 minute (preferably first time decocts 45 minutes), second time decocts 20-30 minute (preferably second time decocts 25 minutes), filter, merge twice decocting liquid;
(5) step (4) gained medicinal residues are continued the clear water adding 3.5 times amount, slow fire boiling 10-20 minute (preferably slow fire boiling 15 minutes), filter, filtrate and above-mentioned decocting liquid merge, and continue heating and be concentrated into original liquid volume 1/2, sterilizing, encapsulation, to obtain final product.
5. the preparation method of a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction according to claim 4, is characterized in that, the middle 50-90 mesh sieve excessively of step (1) (preferred 60-80 mesh sieve excessively, mistake 70 mesh sieve be more preferably).
6. the preparation method of a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction according to claim 4, is characterized in that, temperature dry in step (2) is 43-77 DEG C (preferred dry temperature is 55-65 DEG C, and the temperature of the drying be more preferably is 60 DEG C).
7. the preparation method of a kind of nasopharyngeal carcinoma replenishing YIN and removing heat decoction according to claim 4, is characterized in that, in step (2) dry 4-5 hour (preferably dry 4.5 hours).
8. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable pill, preparation method is as follows:
(1) get sand and be placed in pot, after intense fire is made popular, add clean Squama Manis, be stirred to cokled surface, in time golden yellow, take out, shakeout, cools, and smashs to pieces, crosses 60 mesh sieves, for subsequent use; Retinervus Luffae Fructus is put in frying pan, and intense fire heats, and fries to surface coke black, inner burnt brown, fire extinguishing star, and taking-up cools, and porphyrize is for subsequent use;
(2) crude drug except Squama Manis and Retinervus Luffae Fructus is placed in thermostatic drying chamber, in 53-77 DEG C of freeze-day with constant temperature 3.5-6.5 hour (being preferable over 65 DEG C of freeze-day with constant temperature 5 hours), take out, being placed in pulverizer, to be ground into fine powder for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, with the general ball of alcohol, make the pill of Semen Firmianae size, to obtain final product.
9. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable granule, preparation method is as follows:
(1) Squama Manis, Semen Impatientis and Periostracum Cicadae are placed in medicine pot respectively, slow fire heating is dried, and then smashs into fine powder to pieces, for subsequent use;
(2) Radix Trichosanthis, Radix Clematidis, Retinervus Luffae Fructus, Radix Cynanchi Auriculati, Fructus Forsythiae, the Radix Astragali and Radix Aristolochiae Kaempferi are together placed in 77 DEG C of drying baker, freeze-day with constant temperature 20-40 minute (preferred freeze-day with constant temperature 25 minutes), take out, smash into fine powder to pieces, for subsequent use;
(3) by step (1) and the mixing of step (2) gained raw material medicated powder, 70-90 mesh sieve (preferred mistake 80 mesh sieve) is crossed, for subsequent use;
(4) Herba Taraxaci, Semen Helianthi, Rhizoma Paridis, Poria and Folium Citri tangerinae are together placed in medicinal cupping, add clear water and do not have powder, slow fire boiling twice, each respectively decoction 25-35 minute (preferably each each decoction 30 minutes), filter, collecting decoction, it is the thick paste of 1.18-1.20 that decocting liquid continues to be evaporated to 70 DEG C of relative densities, for subsequent use;
(5) joined in above-mentioned thick paste by step (3) gained mixing fine powders, stir, then add dextrin fine powder and corn starch (thick paste powder: Bidismutose: amylum pregelatinisatum=6:1.5:1.1), granulate, cross No. six sieves, subpackage, to obtain final product.
10. a kind of nasopharyngeal carcinoma replenishing YIN and removing heat preparation as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable powder, preparation method is as follows:
(1) all crude drug are together placed in Chinese medicine air drier, in 70-90 DEG C of dry 2-3 hour (being preferable over 80 DEG C of dryings 2.5 hours), taking out, be ground into fine powder, for subsequent use;
(2) by above-mentioned raw materials medicated powder mix homogeneously, cross 60-120 mesh sieve (preferred mistake 90 mesh sieve), be encapsulated into bag, every bag of 20-30g(preferably every bag of 25g), to obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510104999.9A CN104644977A (en) | 2015-03-11 | 2015-03-11 | Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510104999.9A CN104644977A (en) | 2015-03-11 | 2015-03-11 | Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104644977A true CN104644977A (en) | 2015-05-27 |
Family
ID=53236947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510104999.9A Pending CN104644977A (en) | 2015-03-11 | 2015-03-11 | Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104644977A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1141784A (en) * | 1995-07-28 | 1997-02-05 | 皮敦厚 | Anti-cancer medicine and preparation method thereof |
| CN1679898A (en) * | 2005-01-13 | 2005-10-12 | 刘桂香 | Chinese medicine composition for treating hepatitis and cancers |
| CN101953974A (en) * | 2010-09-09 | 2011-01-26 | 周小军 | Chinese medicament for treating Epstein-Barr (EB) virus infectors |
-
2015
- 2015-03-11 CN CN201510104999.9A patent/CN104644977A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1141784A (en) * | 1995-07-28 | 1997-02-05 | 皮敦厚 | Anti-cancer medicine and preparation method thereof |
| CN1679898A (en) * | 2005-01-13 | 2005-10-12 | 刘桂香 | Chinese medicine composition for treating hepatitis and cancers |
| CN101953974A (en) * | 2010-09-09 | 2011-01-26 | 周小军 | Chinese medicament for treating Epstein-Barr (EB) virus infectors |
Non-Patent Citations (2)
| Title |
|---|
| 姜苗等: "鼻咽癌的中西医结合诊治", 《中国临床医生杂志》 * |
| 王菁平等: "715例癌症患者中药煎剂处方分析", 《中国药房》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103393821A (en) | Traditional Chinese medicine composition for treating chronic pelvic inflammation and preparation method thereof | |
| CN105213974A (en) | One treats lymphadenomatous Chinese medicine composition and application thereof | |
| CN103285343B (en) | Medicine for treating liver cancer and preparation method thereof | |
| CN104771578A (en) | Traditional Chinese medicine for treating allergic rhinitis | |
| CN104056242A (en) | Traditional Chinese medicine composition for treating acute cholecystitis and preparation method thereof | |
| CN102614466B (en) | Traditional Chinese medical preparation for treatment of lung adenocarcinoma | |
| CN105853901A (en) | Preparation for cancer patients to take during radiotherapy and chemotherapy, and method for preparing preparation | |
| CN104147573A (en) | Heat clearing and toxin removing preparation for treating wind-induced headache | |
| CN103285130B (en) | Chinese medicine composition for liver cancer treatment and preparing method thereof | |
| CN104644977A (en) | Preparation capable of nourishing yin and clearing away heat for treating nasopharyngeal carcinoma and preparation method thereof | |
| CN111195299B (en) | Chinese medicinal composition for treating hepatic fibrosis and preparation method thereof | |
| CN105663551A (en) | Traditional Chinese medicine preparation for patient suffering from pancreatic cancer to take after operation as well as preparation method | |
| CN105412673A (en) | Drug for treating Hashimoto disease and preparing method thereof | |
| CN105012789A (en) | Composition for treating cervical cancer and preparation method thereof | |
| CN104435651A (en) | Traditional Chinese medicine for protecting eyes and relieving visual fatigue | |
| CN104644978A (en) | Pure traditional Chinese medicine preparation for treating nasopharyngeal carcinoma and preparation method thereof | |
| CN104622983A (en) | Traditional Chinese medicine composition for treating proctitis and preparation method thereof | |
| CN104644981A (en) | Phlegm-eliminating and stagnation-dispersing agent for nasopharyngeal carcinoma and preparation method of phlegm-eliminating and stagnation-dispersing agent | |
| CN104524149A (en) | Pharmaceutical composition for preventing and treating acute nephritis and application thereof | |
| CN104367954A (en) | Traditional Chinese medicine decoction for treating angina | |
| CN104474296A (en) | Traditional Chinese medicine for treating cancers | |
| CN105106800A (en) | Preparation for treating ovarian cancers and preparation method thereof | |
| CN104758419A (en) | Blood-activating and hardness-softening medicament for nasopharynx cancer and preparation method thereof | |
| CN105853637A (en) | Traditional Chinese medicine composition with synergetic effect on radiotherapy and chemotherapy, and preparation method thereof | |
| CN106390011A (en) | Mammary node stasis-removing capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: Shanghai Road, Xingqing District of Yinchuan city the Ningxia Hui Autonomous Region 750000 District 2 Building No. 485 treasure 1-401 Applicant after: Wang Lihu Address before: 250000 Shandong Province, Ji'nan City District nanxinzhuang Street No. 37 Longhai Garden Applicant before: Wang Lihu |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150527 |