CN104630009A - Liver protecting liquor resisting alcoholic liver damage and preparation method thereof - Google Patents

Liver protecting liquor resisting alcoholic liver damage and preparation method thereof Download PDF

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Publication number
CN104630009A
CN104630009A CN201510086520.3A CN201510086520A CN104630009A CN 104630009 A CN104630009 A CN 104630009A CN 201510086520 A CN201510086520 A CN 201510086520A CN 104630009 A CN104630009 A CN 104630009A
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China
Prior art keywords
liver
liquor
protecting
alcohol tolerance
white spirit
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Granted
Application number
CN201510086520.3A
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Chinese (zh)
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CN104630009B (en
Inventor
张光雄
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Neu (Shanghai) Food Technology Co., Ltd.
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Wine Pocket (shanghai) Klc Holdings Ltd
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Priority to CN201510086520.3A priority Critical patent/CN104630009B/en
Publication of CN104630009A publication Critical patent/CN104630009A/en
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Publication of CN104630009B publication Critical patent/CN104630009B/en
Expired - Fee Related legal-status Critical Current
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)

Abstract

The invention relates to liver protecting liquor resisting alcoholic liver damage and a preparation method thereof. The liver protecting liquor resisting alcoholic liver damage comprises the raw materials in parts by weight as follows: 400-800 parts of liquor, 20-40 parts of kudzuvine root, 20-40 parts of hawthorns, 20-40 parts of pawpaws and 20-40 parts of wolfberry fruit. The liver protecting liquor resisting alcoholic liver damage can furthest give play to the combined action of the medicinal materials, the liquor is soft in wine body, soft-sweet, tasty and refreshing, harmonious in fragrance, fresh in taste and has the function of resisting alcoholic liver damage, the effect for reducing liver damage is obvious, the problem of poor stability of the liquor is solved especially after the additive is used.

Description

Liver-protecting white spirit of alcohol tolerance liver injury and preparation method thereof
Technical field
The present invention relates to the manufacture field of white wine, be specifically related to liver-protecting white spirit of a kind of alcohol tolerance liver injury and preparation method thereof.
Background technology
White wine take Cereals as main raw material, with Daqu, little song or wheat bran and distiller's yeast etc. for saccharifying ferment, through boiling, saccharification, fermentation, distillation and the liquor made.Also known as liquor, white spirit, aquavit etc.Vinosity colourless (or micro-Huang) is transparent, and fragrant odour is pure, and entrance is sweet refreshing clean, and ethanol content is higher, through store aging after, have based on the compound fragrant of ester class.
White wine has another name called liquor, white spirit, is the traditional beverages wine of China, welcomes by Chinese very much.Record according to Compendium of Material Medica: " also, original when unit, its method heavy wine and grain enter rice steamer (referring to steamer) to liquor Fei Gufa, steam and make on gas, hold drip dew with device." can draw thus, the production of China's white wine has very long history.
White wine is the distinctive a kind of liquor of China.The wine degree of white wine, generally more than 41 degree, how more than 55 degree, is generally no more than 65 degree.Low powered posterior chamber white wine refers to and have employed degree of falling technique, and wine degree, generally at 38 degree, even reaches the white wine of degree more than 20, is called for short low alcohol.The degree of falling of wine generally adopts and adds highly purified distilled water to realize in female wine.
So-called " Chen Yuexiang got over by wine ", refers to the white wine of more than 38 degree more.These white wine only need the dated date manufactured, do not need the dated quality guaranteed period.But for low powered posterior chamber white wine, be not but " more Chen Yuexiang ".Research finds, it is all rise that the total acid in white wine is deposited in process at shelf-lives, and the amplitude of 30 ° of wine risings is larger, and 20% ~ 28%, the 38 ° of wine that rise every year on average rise 13% ~ 22% every year on average.In storage process, the major cause that acid increases is: a, white wine occur hydrolysis phenomena depositing in process, generates corresponding acid and ethanol after Ester hydrolysis.The volatility coefficient of b, acid is little, not volatile in storage process.And total ester in white wine to deposit in process at shelf-lives be all decline, the amplitude that 30 ° of wine declines is larger, and 7% ~ 13%, the 38 ° of wine that decline every year on average decline 5% ~ 9% every year on average.For low alcohol, due to CH 3cH 2oH concentration is lower, H 2o concentration is higher, and the speed of forward hydrolysis, thus hydrolysis causes total ester to deposit the major cause declined in process at shelf-lives.
Health-care spirit or medicinal liquor, generally take white wine as base wine, but the traditional Chinese medicine ingredients of some medicine-food two-purposes is added in order to possess health-care effect, in order to ensure the drug effect of traditional Chinese medicine ingredients, and facilitate quoting of specific crowd, the medicinal liquor with health-care effect on market is all 35 degree or the lower low powered posterior chamber white wine of the number of degrees usually.Therefore, health-care spirit generally has the less stable of low powered posterior chamber white wine, between staging life, and degradation shortcoming under the rising of acid amount, ester amount.
Summary of the invention
One of technical problem to be solved by this invention is to provide a kind of liver-protecting white spirit of alcohol tolerance liver injury.
Two of technical problem to be solved by this invention is to provide the preparation method of the liver-protecting white spirit of above-mentioned alcohol tolerance liver injury.
The scheme solved this technical problem is:
A liver-protecting white spirit for alcohol tolerance liver injury, comprises following weight parts raw material composition: white wine 400-800 part, root of kudzu vine 20-40 part, hawthorn 20-40 part, pawpaw 20-40 part, wolfberry fruit 20-40 part.
Preferably,
Described white wine is the white wine of wine degree 25-38 degree.
Described white wine be scent type or aromatic Chinese spirit.
The liver-protecting white spirit of described alcohol tolerance liver injury can also comprise the additive of 1-9 weight part.
Preferred further, described additive, comprises the component of following weight parts: 3-hydroxyl-2-ethyl-pyrokomane 10-30 part, Xylitol 20-40 part, carrageenin 10-20 part.
Present invention also offers the preparation method of the liver-protecting white spirit of described alcohol tolerance liver injury, it comprises the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter.
Preferably,
Step (1) described soak time is 15-30 days.
Soaking conditions is soak under normal temperature (25 ± 5 DEG C) air-proof condition.
After step (2), additive can be added by proportioning, the liver-protecting white spirit of the obtained preferred alcohol tolerance liver injury containing additive.
In the present invention,
Pawpaw, Chinese medicine name.For the dry almost ripe fruit of rosaceous plant chaenomeles lagenaria.Summer, autumn two gather when season, fruit was greenish-yellow, and put in boiling water and scald to crust canescence, double vertical profile, dries.Function: stimulate the circulation of the blood and cause the muscles and joints to relax, and effect of stomach dampness elimination.Compendium of Material Medica: the main cholera of pawpaw tells profit convulsion, beriberi, all the spleen-stomach diseases, and non-hepatic disorder also.Though the main muscle of liver, convulsion is then attacked caused by imapirment of the spleen and stomach by heresy that is damp and hot, cold-dampness, therefore myospasm must arise from sufficient calf, and it is bright that calf and penis all belong to sun.Pawpaw controls convulsion, and also, reason spleen and cut down liver also, native disease then gold declines and wood is contained non-beneficial muscle, therefore with the dissipation of sour Wen Yishou taste, and it is evil with flat liver to borrow it to walk muscle, is rush down wood in soil to help gold also.Then native must order and Jin Shouyin put down by wood." Plain Questions " cloud: sour flavor being apt to act on the tendon, being unsuitable for tendon-disease to be treated with drugs of sour flavor.The Meng numerous cloud: many food pawpaws damage tooth and bone.The bright of clear felling liver is tested, and pawpaw is started with, foot is lunar, and be taste medicine, non-liver medicine, benefit can be levied.
The root of kudzu vine, Chinese medicine name.For the dry root of legume pueraria lobata, practise and claim elegant jessamine.Autumn, season in winter two excavate, and take advantage of fresh-cut and become sheet or fritter; Dry.Sweet, pungent, cool.There is expelling pathogenic factors from muscles for reducing heat, promoting eruption, promote the production of body fluid to quench thirst, rise the merit of positive antidiarrheal.Be usually used in illness that has not attacked the vital organs of the human body heating, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, diarrhea due to hypofunction of the spleen." book on Chinese herbal medicine converges and says ": " root of kudzu vine, fresh breeze is trembled with fear, and only shows heresy, expelling pathogenic factors from muscles and skin heat, only polydipsia.Rush down the medicine of stomach fire also.Taste the medicine that loose heresy is delivered in sight, its product are also many, pull out sun battalion divide cold as Chinese ephedra, the wind that cassia twig Xie Taiyangwei divides, windproof, purple perilla falls apart the chill of the sun at table, and Jehol Ligusticum Rhizome, notopterygium root fall apart the cold-dampness of the sun at table, all claim to disperse medicine also, and dispersing of the root of kudzu vine, also enter the sun, also dispersing wind and cold, different again, if non-numb, osmanthus, Soviet Union, anti-, pungent fragrant temperature is dry, disperse and damage middle gas mistake also; If non-Jehol Ligusticum Rhizome, notopterygium root, disperse and have consumption ying blood anxiety also.”
Hawthorn, Chinese medicine name.For the dry mature fruit of rosaceous plant Fruit of Pashi Pear or hawthorn.Gather during fruit maturation in autumn, section, dry." Records of Tradition Chinese and Western Medicine in Combination ": hawthorn, if help it with sweet medicine, Removing Blood Stasis and do not hinder new blood, open strongly fragrant gas and do not hinder healthy tendency, the outstanding peace of its property also.
Wolfberry fruit is traditional rare traditional Chinese medicine, is again a kind of nutritional supplements.In the list of 63 kinds of medicine-food two-purposes of Ministry of Health's announcement, rank first.As traditional Chinese medicine, the flat taste of wolfberry fruit is sweet, has effect of nourishing liver and kidney, replenishing vital essence to improve eyesight, moistening lung.Pass through chemical composition analysis, the fruit of wolfberry fruit detects containing nutritive ingredients such as abundant natural Beta-carotene, vitamins C, wolfberry fruit protein-polysaccharide, trimethyl-glycine, linolic acid and iron, phosphorus, calcium, has qi-restoratives to calm the nerves, improving eyesight is dispeled the wind, nourshing kidney moistening lung and protect the effects such as liver is antitumor.Wolfberry fruit contains the required nutritive substance of abundant carotene, multivitamin and the healthy eye such as calcium, iron, therefore has the merit of improving eyesight, is commonly called as " bright eye ".What ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN caused looks thing duskization and nyctalopia, usually uses wolfberry fruit.Further, wolfberry fruit is from the Book of Songs " combines in luxuriant Qi ", and just for medicine, the history in existing more than 3000 years so far, just has the alone wolfberry fruit of Jin Chaoge flood to smash juice from ancient times and drip order, the story for the treatment of ophthalmology illness.The name of wolfberry fruit, first appeared in Shennong's Herbal, is listed as top grade, very popular over the past thousands of years.
3-hydroxyl-2-ethyl-pyrokomane, No. CAS: 4940-11-8.China GB2760-86 is defined as the food and spices that allow to use, and being a kind of fragrance synergistic agent, is a kind of safety non-toxic, has flavouring, increases sweet, to protect the effects such as fragrant and covering smell foodstuff additive.
Xylitol, No. CAS: 87-99-0.
Carrageenin, No. CAS: 11114-20-8.Carrageenin is a kind of polysaccharide extracted from marine red alga (mainly various Eucheuma muricatum (Gmel.) Web. Van Bos.), and its chemical structure is the linear polysaccharide compound that D-semi-lactosi and 3,6-dehydration-D-galactose residue form, with ester formula sulfate group on residue.
The liver-protecting white spirit of alcohol tolerance liver injury of the present invention, the comprehensive action of various medicinal material can be played to greatest extent, wine body is soft, sweet tasty and refreshing, all fragrant harmonies, taste is refreshing clean, there is the effect of alcohol tolerance liver injury, to the Be very effective reducing liver injury, after especially employing additive, solve the problem of low powered posterior chamber white wine poor stability.In prior art, white wine does not normally add additive, but due to medicinal liquor or the health-care spirit number of degrees lower, along with the time can generating portion acidifying, acid number rises, ester amount declines, Xylitol in additive can react with acid, generates the ester with aromatising flavour with its reaction, and carrageenin is as a kind of dispersion agent, the liver-protecting white spirit of antagonism alcoholic liver injury serves stable effect, and 3-hydroxyl-2-ethyl-pyrokomane can remove the peculiar smell of the Chinese medicinal materials in health-care spirit.Unexpectedly, research finds: when to use 3-hydroxyl-2-ethyl-pyrokomane, Xylitol and carrageenin simultaneously, the decline slowing down ester amount in health-care spirit is served to the effect of synergy.The liver-protecting white spirit preparation method of alcohol tolerance liver injury of the present invention is simple, easy preservation.
Embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Get 35 degree of white wine 600 kilograms, put into pawpaw 30 kilograms, the root of kudzu vine 30 kilograms, hawthorn 30 kilograms, wolfberry fruit 30 kilograms, sealing, soak at room temperature 30 days, remove peculiar smell and muddiness with active carbon for liquor SB-204, filter, obtain the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 1.
Show through acute toxicity test result, acute toxicity is extremely low, and security is high; Pharmacodynamic experiment result shows, has the effect of alcohol tolerance liver injury, from pathological section and Antioxidant index, to the Be very effective reducing liver injury.
The liver-protecting white spirit of alcohol tolerance liver injury of the present invention, can play the comprehensive action of various medicinal material to greatest extent, wine body is soft, sweet tasty and refreshing, all fragrant harmonies, and taste is refreshing clean, has the effect of alcohol tolerance liver injury, to the Be very effective reducing liver injury.
Embodiment 2-5
Take each raw material according to the additive formulations of embodiment 2-5 in table 2, mix, obtained additive.Take 3 grams of additives to join in the liver-protecting white spirit of the obtained alcohol tolerance liver injury of 720 grams of embodiments 1, be uniformly mixed, make the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 2-5.
Table 1: additive formulations table (unit: kilogram)
3-hydroxyl-2-ethyl-pyrokomane Xylitol Carrageenin
Embodiment 2 20 30 15
Embodiment 3 / 30 35
Embodiment 4 20 45 /
Embodiment 5 20 / 45
Test case
Detect lucifuge normal temperature sealed type storage after 20 months, the content of main ester compound in the health-care spirit of embodiment 1-5, test result is in table 2.
Table 2: embodiment 1-5 health-care spirit ester compound is containing scale (unit: g/L)
Ethyl acetate Ethyl lactate Ethyl butyrate Ethyl hexanoate
Just prepared embodiment 1 0.6020 0.7885 0.0185 0.0232
Embodiment 1 after 20 months 0.3788 0.4211 0.0084 0.0126
Embodiment 2 after 20 months 0.4652 0.5921 0.0155 0.0186
Embodiment 3 after 20 months 0.4173 0.4956 0.0122 0.0142
Embodiment 4 after 20 months 0.4384 0.5102 0.0133 0.0145
Embodiment 5 after 20 months 0.4091 0.4825 0.0124 0.0137
From experimental result, store after 20 months, in the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 1-5, several main ester compound content has maintained higher level, maintains good aromatising flavour and mouthfeel, especially, after embodiment 2-4 employs additive, ester class content is higher.
More particularly, embodiment 2 employs Xylitol, carrageenin, 3-hydroxyl-2-ethyl-pyrokomane three are composite, compared with embodiment 3-5 adopt respectively in Xylitol, carrageenin and 3-hydroxyl-2-ethyl-pyrokomane any two kinds composite, lucifuge normal temperature sealed type storage after 20 months ester compound content maintain higher level, three's synergy, effect is more obvious.

Claims (8)

1. a liver-protecting white spirit for alcohol tolerance liver injury, is characterized in that, comprises following weight parts raw material composition: white wine 400-800 part, root of kudzu vine 20-40 part, hawthorn 20-40 part, pawpaw 20-40 part, wolfberry fruit 20-40 part.
2. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 1, is characterized in that: the wine degree of the liver-protecting white spirit of described alcohol tolerance liver injury is 25-38 degree.
3. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 1, is characterized in that: the liver-protecting white spirit of described alcohol tolerance liver injury be scent type or aromatic Chinese spirit.
4. the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 1-3, is characterized in that: the additive also comprising 1-9 weight part.
5. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 4, is characterized in that: described additive, comprises the component of following weight parts: 3-hydroxyl-2-ethyl-pyrokomane 10-30 part, Xylitol 20-40 part, carrageenin 10-20 part.
6. the preparation method of the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 1-3, is characterized in that, comprise the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter.
7. preparation method as claimed in claim 6, is characterized in that: step (1) described soak time is 15-30 days.
8. the preparation method of the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 4-5, is characterized in that, comprise the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter;
(3) additive is added.
CN201510086520.3A 2015-02-23 2015-02-23 Liver-protecting white spirit of resisting alcoholic hepatic injury and preparation method thereof Expired - Fee Related CN104630009B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109136025A (en) * 2018-07-11 2019-01-04 山西三十七度酒业有限公司 A kind of composite fragrant assembled alcoholic drinks and its preparation method
CN109306308A (en) * 2017-07-27 2019-02-05 甄青松 A kind of odor type health white wine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5558087A (en) * 1978-10-23 1980-04-30 Sumie Hihara Low calorie apricot liquor
CN1153818A (en) * 1996-10-23 1997-07-09 宁夏农林科学院农副产品贮藏加工研究所 Fresh lycium chinense with stalk wine and its brewage process
CN101874857A (en) * 2010-05-28 2010-11-03 劲牌有限公司 Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof
CN102660445A (en) * 2012-06-06 2012-09-12 重庆修贤商贸有限公司 Functional low-damage healthcare wine
CN103103097A (en) * 2013-01-16 2013-05-15 丽水市林业科学研究院 Rhizoma polygonati kidney tonifying wine and preparation method thereof
CN103666982A (en) * 2012-09-08 2014-03-26 哈尔滨艾克尔食品科技有限公司 Pineapple jelly wine

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5558087A (en) * 1978-10-23 1980-04-30 Sumie Hihara Low calorie apricot liquor
CN1153818A (en) * 1996-10-23 1997-07-09 宁夏农林科学院农副产品贮藏加工研究所 Fresh lycium chinense with stalk wine and its brewage process
CN101874857A (en) * 2010-05-28 2010-11-03 劲牌有限公司 Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof
CN102660445A (en) * 2012-06-06 2012-09-12 重庆修贤商贸有限公司 Functional low-damage healthcare wine
CN103666982A (en) * 2012-09-08 2014-03-26 哈尔滨艾克尔食品科技有限公司 Pineapple jelly wine
CN103103097A (en) * 2013-01-16 2013-05-15 丽水市林业科学研究院 Rhizoma polygonati kidney tonifying wine and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109306308A (en) * 2017-07-27 2019-02-05 甄青松 A kind of odor type health white wine
CN109136025A (en) * 2018-07-11 2019-01-04 山西三十七度酒业有限公司 A kind of composite fragrant assembled alcoholic drinks and its preparation method

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Address after: No. 3552, room 3, No. 200, Huan Cheng Road, Shanghai, Shanghai

Patentee after: Neu (Shanghai) Food Technology Co., Ltd.

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Granted publication date: 20160608

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