CN104623026B - Treat Chinese medicine preparation of proctitis ulcerosa and preparation method thereof - Google Patents
Treat Chinese medicine preparation of proctitis ulcerosa and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation for treating proctitis ulcerosa, the primary raw material of following weight proportions is taken to be prepared：39 parts of cuttlebone, 15 30 parts of the root bark of shaggy-fruited dittany, 10 30 parts of myrrh; 39 parts of Chinese gall, 3 10 parts of cow-bezoar, 5 15 parts of keel; 8 12 parts of indigo naturalis, 10 20 parts of Poria cocos, 10 20 parts of pappy shell; 59 parts of wrinkled giant hyssop, 36 parts of borneol, 3 15 parts of Radix Angelicae Sinensis; 15 40 parts of rhizoma polygoni paleacei, 10 30 parts of Hericium erinaceus, 39 parts of the Radix Astragali; 10 20 parts of the dried immature fruit of citron orange, 6 18 parts of radish.The Chinese medicine preparation is to proctitis ulcerosa significant effect, to suffering from abdominal pain, having blood in stool as caused by proctitis ulcerosa, weight loss, the symptom such as tenesmus, vomiting have good mitigation, more optionally common medicinal materials in side of the invention, it is cheap, alleviate the financial burden of patient.
Description
Technical field
The invention discloses treatment proctitis ulcerosa Chinese medicine preparation, more particularly, to a kind of proctitis ulcerosa for the treatment of
Chinese medicine preparation and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
Chronic nonspecific ulcerative lesion is confined to be referred to as proctitis ulcerosa during rectum.Bloody diarrhea is most common
Early symptom.Other symptoms have successively stomachache, have blood in stool, weight loss, it is tenesmus, vomiting etc..The cause of disease of proctitis ulcerosa
So far it is still not clear.Genetic factors may have certain status.Psychological factor has critical role in disease progression.It is now recognized that
The morbidity of IBD is the result that allogenic material causes host response, gene and Immunological Effect triple interaction.
Clinical manifestation：The initial performance of proctitis ulcerosa can have many forms.Bloody diarrhea is most common early stage disease
Shape.Other symptoms have successively stomachache, have blood in stool, weight loss, it is tenesmus, vomiting etc..Arthritis, iris are mainly shown as once in a while
Cyclitis, hepatosis and cutaneous lesions.It is then a uncommon sign relatively to generate heat, this disease in Most patients
Show as chronic, low pernicious, be in acute, severe fulminant type in small number of patients (accounting for 15%).These patients show as frequently
Bloody stool, can up to 30 times/day, with high fever, stomachache.Sign is directly related with stadium and clinical manifestation, and patient often has body weight to subtract
Light and pale complexion, in disease activity phase abdomen examination, lower abdomen often has tenderness.May have acute abdomen sign occur together heat and intestines
The sound that rings is reduced, particularly evident in acute attack or fulminant type case.Due to frequently suffering from diarrhoea, anal skin scratch, stripping can also occur
De-, anal fissure or anal fistula.Digital rectal examination sense pain.Showed outside rectum：The inspection of skin, mucous membrane, tongue, joint and eye extremely weighs
Will.
The B of Authorization Notice No. CN 101254276 (application number 200810054678.2) patent discloses a kind for the treatment of and put
The Chinese medicine preparation of penetrating property rectitis, it is characterised in that be made up of the raw material of following weight ratio, pseudo-ginseng 3-6g, borneol 3-6g, donkey-hide gelatin
5-10g, bletilla 10-30g, garden burnet 15-45g, rheum officinale 6-9g, hairyvein agrimony 15-30g.B (the Shens of Authorization Notice No. CN 103356816
Number 201310294459.2) patent that please discloses a kind of Chinese medicine preparation of therapeutic radiation rectitis, it is characterised in that：In this
Medicine preparation is made up of the Chinese medicine of following parts by weight：Chinese snapweed stem and leaf 10-15 parts, henry hemsleya root 5-10 parts, japanese mazus herb 12-17 parts, golden cypress 12-
15 parts, wolf's milk 7-11 parts, Japanses beauty-berry 13-18 parts, henry clematis root of leaf 9-16 parts, caudate sweetleaf leaf 45-50 parts, procumbent Indian mallow root 8-15 parts, fern fiber crops
25-28 parts, Radix Astragali 20-35 parts, red halloysite 20-30 parts.
As can be seen here, Chinese medicine occupies very important status in terms of rectitis is treated, but preparation method is complicated, mostly
Number is all decoction, first, inconvenient carrying, second, only for oral administration, decoction adult takes can be with, but children fear hardships, and are not suitable for children
Take.
The content of the invention
With the continuous development of Chinese traditional Chinese medicine, in treatment and control in rectitis, during people appreciate gradually
Medicine treatment proctitis ulcerosa disease therapeutic process has no side effect, and patient bears the advantage that pain is small, and cost is saved relatively, for existing
There is the present situation of western medical treatment proctitis ulcerosa, an object of the present invention is the Chinese medicine system for providing treatment proctitis ulcerosa
Agent, there is the characteristics of easy to operate, evident in efficacy, and it is low as raw material, cost using Chinese medicine relatively conventional in the localities
It is honest and clean.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
The Chinese medicine preparation of proctitis ulcerosa is treated, takes the primary raw material of following weight proportions to be prepared：Cuttlebone 3-9
Part, root bark of shaggy-fruited dittany 15-30 parts, myrrh 10-30 parts, Chinese gall 3-9 parts, cow-bezoar 3-10 parts, keel 5-15 parts, indigo naturalis 8-12 parts, Fu
Siberian cocklebur 10-20 parts, pappy shell 10-20 parts, wrinkled giant hyssop 5-9 parts, borneol 3-6 parts, Radix Angelicae Sinensis 3-15 parts, rhizoma polygoni paleacei 15-40 parts, Hericium erinaceus
10-30 parts, Radix Astragali 3-9 parts, dried immature fruit of citron orange 10-20 parts, radish 6-18 parts.
Treat proctitis ulcerosa Chinese medicine preparation, preferable scheme, take following weight proportions primary raw material prepare and
Into：Cuttlebone 5-9 parts, root bark of shaggy-fruited dittany 16-25 parts, myrrh 15-25 parts, Chinese gall 4-8 parts, cow-bezoar 4-8 parts, keel 8-13 parts are blue or green
Black pigment used by women in ancient times to paint their eyebrows 9-11 parts, Poria cocos 12-18 parts, pappy shell 14-18 parts, wrinkled giant hyssop 6-8 parts, borneol 3.5-5 parts, Radix Angelicae Sinensis 6-14 parts, rhizoma polygoni paleacei 20-
38 parts, Hericium erinaceus 15-28 parts, Radix Astragali 5-7 parts, dried immature fruit of citron orange 13-18 parts, radish 10-14 parts.
The Chinese medicine preparation of proctitis ulcerosa is treated, more preferably preferable scheme, takes the primary raw material systems of following weight proportions
It is standby to form：8 parts of cuttlebone, 20 parts of the root bark of shaggy-fruited dittany, 20 parts of myrrh, 6 parts of Chinese gall, 5 parts of cow-bezoar, 10 parts of keel, 10 parts of indigo naturalis, Poria cocos
15 parts, 15 parts of pappy shell, 7 parts of wrinkled giant hyssop, 4 parts of borneol, 12 parts of Radix Angelicae Sinensis, 30 parts of rhizoma polygoni paleacei, 25 parts of Hericium erinaceus, 6 parts of the Radix Astragali, the dried immature fruit of citron orange 15
Part, 12 parts of radish.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment proctitis ulcerosa.
The preparation method of the Chinese medicine preparation of proctitis ulcerosa is treated, step is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1-2 hours, sesame oil is instilled, then
It is secondary to decoct 5 minutes, wait that decocting well-done cuttlebone, keel and pappy shell is placed in steaming 10-30 minutes on food steamer, taking-up frying is crisp,
It is stand-by to be ground into smalls；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Vinegar (preferably rice vinegar) is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is fallen while hot
Enter into crock, close the lid, boil in a covered pot over a slow fire 13-16 hours, take the hot pot dryouied, add ready-mixed oil, treat that hot pot surrounding has blue or green cigarette to emerge
When, the Chinese medicine boiled in a covered pot over a slow fire is immediately placed in pot, frying 3-8 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in immersion 3-5 hours in light-coloured vinegar, is placed in steaming 40-60 minutes on food steamer,
Thick liquid is ground into big iron spoon, thick liquid is dried into 10-20 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, add the water of 2-4 times of raw material weight for the first time, decoct 20-40 minutes, filtering, obtain filtrate 1, second plus 3-5 times of filter residue weight
Water, intense fire is fried open, and turns to be cooked by slow fire 1 hour, filters, and obtains 1-3 times of water of filtrate 2, third time plus filter residue weight, and culture is pan-fried
Boil 10-20 minutes, filter, obtain filtrate 3, filtrate merges three times decocts 10 minutes again, adds bulk drug obtained by step (1)-(3)
And indigo naturalis, it is sufficiently stirred and decocts, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
The preparation method of above-mentioned Chinese medicine preparation, 1. step adds water to cook 1.3-1.8 hours after, sesame oil is instilled, decocts 5 again
Minute (preferable, after adding water to cook 1.5 hours, to instill sesame oil, decoct 5 minutes again).
2. the preparation method of above-mentioned Chinese medicine preparation, step are boiled in a covered pot over a slow fire 14-15 hours (preferable, to boil in a covered pot over a slow fire 14.5 hours).
2. the Chinese medicine boiled in a covered pot over a slow fire is immediately placed in pot by the preparation method of above-mentioned Chinese medicine preparation, step, frying 5-7 minutes
(preferable, the Chinese medicine boiled in a covered pot over a slow fire to be immediately placed in pot, frying 6 minutes).
3. the preparation method of above-mentioned Chinese medicine preparation, step are placed in immersion 3.5-4.5 hours in light-coloured vinegar, are placed on food steamer and steam
45-55 minutes (preferable, to be placed in light-coloured vinegar and soak 4 hours, be placed on food steamer and steam 50 minutes).
4. the preparation method of above-mentioned Chinese medicine preparation, step add the water of 2.5-3.5 times of raw material weight, decoct 25-35 for the first time
Minute (preferable, to add the water of 3 times of raw material weight for the first time, decoct 30 minutes).
The preparation method of above-mentioned Chinese medicine preparation, step 4. second plus 3.5-4.5 times of filter residue weight water (preferably, the
Secondary plus 4 times of filter residue weight water).
The Chinese medicine preparation is to proctitis ulcerosa significant effect, to suffering from abdominal pain, having blood in stool, body weight as caused by proctitis ulcerosa
The symptom such as mitigation, tenesmus, vomiting has good mitigation, and the more optionally common medicinal materials in side of the present invention are cheap, subtract
The light financial burden of patient.
The pharmacological effect of each bulk drug is respectively：
Cuttlebone：With astringing to arrest bleeding, relieving leukorrhea by astringents, relieving haperacidity analgesic, the effect of hygroscopic sore.It is usually used in hematemesis and epistaxis,
Uterine bleeding is had blood in stool, emission and spermatorrhea, leukorrhea with reddish discharge, acid regurgitation of having a stomachache；Control bleeding due to trauma, eczema wet sore, unhealing ulcer outside.
The root bark of shaggy-fruited dittany：Nature and flavor：It is bitter；It is salty；It is cold.Channel tropism：The spleen channel；Lung channel；Small intestinl channel；Stomach；Bladder warp.Function：Heat-clearing and damp-drying drug；
Dispelling wind and arresting itching；Removing toxic substances.Cure mainly：Rubella caused by wind-heat wet poison；Eczema；Mange；Jaundice；Damp-heat arthralgia.
Myrrh：Raw property or lymphatic temperament disease, such as raw property arthralgia, sciatica, oral cavity pain, throat pain
Four kinds of form contrast pains, cold cough, moist abundant expectoration, bronchiectasis, eczema running sore, irregular menstruation, difficult urination.Hair tonic is consolidated
Hair, nti-freckle disappear trace, and softening hard masses remove knurl, and except tinea is more created, permanent tooth is good for gum, detoxify etc..Control alopecia capillary, black spot bruise, flat wart is various
Eczema, gum is rotten to the corn, and poisonous insect stings wound etc..Leading to flutter damage, trusted subordinate's blood stasis is traumaticd fracture and falls damage, muscles and bones stasis caused pain, and golden sword is damaged, bitterly can not
Bear, drink is all thrown with wine.
Chinese gall：With fall fire of astringing the lung, relieving diarrhea with astringents, arrest sweating, hemostasis, the effect of hygroscopic sore.It is usually used in chronic cough of deficiency lung,
Lung feverish cough, protracted dysentery and diarrhea, spontaneous sweating, quenches one's thirst, hemorrhoid blood of having blood in stool, traumatism and bleeding, carbuncle sore tumefacting virus, skin moisture fester.
Cow-bezoar：Cow-bezoar gas delicate fragrance, mildly bitter flavor then sweet tea are cool in nature.Available for antipyretic, removing toxic substances, arresting convulsion.Internal treatment of high fever mind
The diseases such as stupor, demented, child convulsion, twitch, external application control abscess of throat, aphtha carbuncle swells, treat toxication.Natural ox gallstone is very precious, state
Price on border is higher than gold, largely uses so-called calculus bovis factitius.
Keel：Base：It is ancient times mammal as the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, ox class, deer class etc..Composition：
The main calcium carbonate of keel and calcium phosphate, still containing iron, potassium, sodium, chlorine, sulfate radical etc..The property of medicine：It is puckery, sweet, put down.The thoughts of returning home, liver, kidney,
Large intestine channel.Function cures mainly：Tranquilizing mind, calming the liver, convergence is astringent or styptic treatment for spontaneous sweating.Palpitaition is cured mainly, seized with terror swollen, insomnia, forgetful, frightened epilepsy is demented,
Dizziness, spontaneous sweating, the enuresis of passing out semen, under uterine bleeding band, chronic diarrhea and dysentery, ulcer does not close up long and wet sore.
Indigo naturalis：Also known as clam powder, indigo-blue flower, it is Acanthaceae acanthaceous indigo platymiscium acanthaceous indigo, polygonaceae arsesmart indigo plant, pulse family wood
Blue platymiscium wood indigo plant, the leaf of Cruciferae woaded blue platymiscium woaded blue or the processed obtained dried powder of cauline leaf or agglomerate.The property of medicine：
This product is navy blue powder, and body is light, easily flies upward, and micro- to have careless stink smell, taste is salty, cold in nature.Composition：Its main component has indigo red,
It is indigo.Found according to modern pharmacological research, the medical instrument have antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing heat and cooling blood, removing toxic substances
Effect, for symptoms such as epidemic heat syndrome macula, abscess of throat, haematemesis, bleeding from five sense organs or subcutaneous tissue, spitting of bloods.
Poria cocos：It is sweet, light, it is mild-natured.The channel tropism thoughts of returning home, lung, spleen, kidney channel.Effect clearing damp and promoting diuresis, invigorating the spleen, calming heart.Cure mainly and be used for
Oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Pappy shell：With astringing the lung, puckery intestines, the effect of analgesic.It is usually used in chronic cough, chronic diarrhea, prolapse of the anus, epigastric pain.
Wrinkled giant hyssop：For dampness taste, abdominal fullness and distention, damp-warm syndrome from the beginning of, vomiting, diarrhea, summer-heat and damp, fever with chilliness, fever with aversion to cold,
The diseases such as chest distress.
Borneol：It can be used for closing card coma, for red eye, swell pain, larynx numbness aphtha, for sore swell and ache curative, not held back after bursting.
Radix Angelicae Sinensis：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot
It is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Rhizoma polygoni paleacei：Base：For the rhizome of polygonaceae arsesmart rhizoma polygoni paleacei.Composition：Rhizoma polygoni paleacei rhizome tannin containing Combination.Medicine
Property：Bitter, acrid, cold.Function cures mainly：Dissipate stasis of blood hemostasis, lower gas disperse accumulations, removing toxic substances, dampness removing.Zhu Zhi wei lump in the abdomen is gathered, and traumatic injury, wound goes out
Blood, spit blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, Amenorrhea, uterine bleeding, chronic gastritis, taste-blindness rate, dyspepsia stagnation, dysentery, enteritis, oedema,
Sore, snake bite, burn and scald.
The Radix Astragali：The Radix Astragali has enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide anti-
Bacterium acts on.Jishengshenqiwan albuminuria can be eliminated, strengthens myocardial contractive power, adjusts blood-sugar content.The Radix Astragali can not only be expanded coronal
Artery, improve myocardial blood supply, improve immunologic function, and be capable of the process of delaying cell aging.
Hericium erinaceus：Base：For tooth bacterium section Hericium fungi Hericium erinaceus, the fructification of Hydnum.Composition：Hedgehog hydnum
A containing Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone, B, C, D, E, F, G, H, Hericium erinaceus alkali etc. in mushroom entity.Dry fructification and contain protein, lipid, fiber and
Glucan.Also contain sterols：Ergosterol etc..Mycelium culture contains Hericium erinaceus pyranone A, B etc..The property of medicine：《National medium-height grass
Medicine collects》：It is " sweet, flat." function cures mainly：Strengthening spleen and nourishing stomach, calm the nerves, anticancer.Physically weak weak, indigestion is cured mainly, is had a sleepless night, stomach and ten
Two Duodenalulcers, chronic gastritis, tumor in digestive tract.
The dried immature fruit of citron orange：Base：For Rutaceae citrus plant bitter orange and its variety or the young fruit of sweet orange.Composition：1. bitter orange：
Fruit mainly contains flavonoids：Aurantiamarin, neohesperidin, aurantiin etc..Seed contains limonin：Ichang papeda bitter principle, Milin of making a noise,
Deacetylnomilin, limonin etc..2. sweet orange fruit mainly contains flavonoids：" narirutin, isosakuranetin -7- rutinoses
Glycosides etc..Pericarp contains flavonoids：Aurantiamarin, aurantiin etc..The property of medicine：It is bitter, pungent, it is slightly cold.Returns spleen, stomach, large intestine channel.Function cures mainly：It is broken
Gas disperse accumulations, resolving sputum remove ruffian.Cure mainly internal stagnation, feeling of fullness distending pain, constipation, weight after rush down dysentery, accumulation of pathogens in chest, the obstruction of qi in the chest, gastroptosis, uterus
Prolapsus, prolapse of the anus.
Radish：Base：For the fresh quench of Cruciferae radish platymiscium radish.Composition：Root glucosinolate containing glycoside, glucose
Raphanin, raphanusin.Phenolic acid class：P-Coumaric Acid, caffeic acid, forulic acid, phenylpyruvic acid, gentianic acid etc..The property of medicine：Acrid, sweet, cool；
Ripe person is sweet, puts down.Returns spleen, stomach, lung, large intestine channel.Function cures mainly：Help digestion, lower gas, resolving sputum, hemostasis.Indigestion is cured mainly, dyspepsia is swollen
It is full, acid regurgitation, regurgitation, food is told, intestines wind, diarrhea, dysentery, constipation, phlegm-heat cough, discomfort in the throat, hemoptysis, spits blood, bleeding from five sense organs or subcutaneous tissue, has blood in stool,
Quench one's thirst, drench worm.Outer treatment sore swells ulcer, the damage stasis of blood swell, scald and pernio.
Chinese medicine preparation of the present invention debates the principle of disease treatment based on traditional Chinese medicine.One divides and is during prepared Chinese medicine preparation use
Two, portion is washed open with hot water, is put into interior use of clean container and is used as enema, another uses taken with boiled water, and the present invention is to treatment
Proctitis ulcerosa is more comprehensive, and rapider, lasting medicine is administered in affected area, alleviates mucous bloody stool, diarrhoea, stomachache, inner urgency
Weigh afterwards, anus cusalgia falls the clinical symptoms such as pain；Improve positive fecal occult blood, colonoscopy mucosa infection and radiation insult；Patient can be improved
Quality of life；Recurrence rate is low, and curative effect is reliable, and effect is stable, has no toxic side effect, and has fabulous treatment to make to proctitis ulcerosa
With present invention is mainly used for nursing application of the clinic to proctitis ulcerosa patient, convenient nursing personnel nurse to patient.
Embodiment
Technical scheme is described in detail with reference to embodiment and experimental example, but protection domain is not limited by this.
Embodiment 1 treats the Chinese medicine preparation of proctitis ulcerosa, takes the primary raw material of following weight proportions to be prepared (often
Part takes 10g)：3 parts of cuttlebone, 15 parts of the root bark of shaggy-fruited dittany, 10 parts of myrrh, 3 parts of Chinese gall, 3 parts of cow-bezoar, 5 parts of keel, 8 parts of indigo naturalis, Poria cocos
10 parts, 10 parts of pappy shell, 5 parts of wrinkled giant hyssop, 3 parts of borneol, 3 parts of Radix Angelicae Sinensis, 15 parts of rhizoma polygoni paleacei, 10 parts of Hericium erinaceus, 3 parts of the Radix Astragali, the dried immature fruit of citron orange 10
Part, 6 parts of radish.
The Chinese medicine preparation of rectitis is treated, preparation process is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1 hour, sesame oil is instilled, again
Decoct 5 minutes, wait to decoct well-done cuttlebone, keel and pappy shell and be placed on food steamer to steam 10 minutes, taking-up frying is crisp, is ground into
Smalls is stand-by；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Rice vinegar is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into crock while hot
It is interior, close the lid, boil in a covered pot over a slow fire 13 hours, take the hot pot dryouied, ready-mixed oil is added, when hot pot surrounding has blue or green cigarette to emerge, by what is boiled in a covered pot over a slow fire
Chinese medicine is immediately placed in pot, frying 3 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in light-coloured vinegar and soaks 3 hours, is placed on food steamer and steams 40 minutes, with big iron
Spoon is ground into thick liquid, and thick liquid is dried 10 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, the water of 2 times of first time plus raw material weight, decoct 20 minutes, filtering, obtain filtrate 1, second of the water for adding 3-5 times of filter residue weight,
Intense fire is fried open, and is turned to be cooked by slow fire 1 hour, is filtered, and obtains 1-3 times of water of filtrate 2, third time plus filter residue weight, and culture decocts 10
Minute, filtering, filtrate 3 obtaining, filtrate merges three times decocts 10 minutes again, adds bulk drug and indigo naturalis obtained by step (1)-(3),
It is sufficiently stirred and decocts, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
Model case one：Qiu XX, female, 38 years old, Jining City in Shandong Province Yanzhou personage, the employee of certain company.Symptom：2013
Cervical carcinoma month after operation, radiation treatment 21 days, stool band purulence blood 3 days, had a small amount of mucus, with diarrhoea watery stool, used fluorine June
Piperazine acid therapeutic effect is bad.Proctoscopy：See that intestinal wall hyperemia, swelling are in russet, give and suspend only radiotherapy, remove examination in hospital
It is diagnosed as proctitis ulcerosa, it is proposed that use present invention gained Chinese medicine preparation.
Using and use the gained Chinese medicine preparation of embodiment 1, bowel lavage simultaneously coordinates oral medication 2 days, and no bloody stool occurs, and disables celestial
Crane grass, be continuing with the medicine 5 days, clinical symptoms are wholly absent, after half a year follow-up do not recur again.
Embodiment 2 treats the Chinese medicine preparation of proctitis ulcerosa, takes the primary raw material of following weight proportions to be prepared (often
Part takes 10g)：9 parts of cuttlebone, 30 parts of the root bark of shaggy-fruited dittany, 30 parts of myrrh, 9 parts of Chinese gall, 10 parts of cow-bezoar, 15 parts of keel, 12 parts of indigo naturalis,
20 parts of Poria cocos, 20 parts of pappy shell, 9 parts of wrinkled giant hyssop, 6 parts of borneol, 15 parts of Radix Angelicae Sinensis, 40 parts of rhizoma polygoni paleacei, 30 parts of Hericium erinaceus, 9 parts of the Radix Astragali, trifoliate orange
It is real 20 parts, 18 parts of radish.
The Chinese medicine preparation of rectitis is treated, preparation process is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 2 hours, sesame oil is instilled, again
Decoct 5 minutes, wait to decoct well-done cuttlebone, keel and pappy shell and be placed on food steamer to steam 30 minutes, taking-up frying is crisp, is ground into
Smalls is stand-by；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Rice vinegar is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into crock while hot
It is interior, close the lid, boil in a covered pot over a slow fire 16 hours, take the hot pot dryouied, ready-mixed oil is added, when hot pot surrounding has blue or green cigarette to emerge, by what is boiled in a covered pot over a slow fire
Chinese medicine is immediately placed in pot, frying 8 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in light-coloured vinegar and soaks 5 hours, is placed on food steamer and steams 60 minutes, with big iron
Spoon is ground into thick liquid, and thick liquid is dried 20 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, the water of 4 times of first time plus raw material weight, decoct 40 minutes, filtering, obtain filtrate 1, second of the water for adding 5 times of filter residue weight is military
Fire is fried open, and is turned to be cooked by slow fire 1 hour, is filtered, and obtains 3 times of water of filtrate 2, third time plus filter residue weight, and culture decocts 20 minutes,
Filtering, obtains filtrate 3, and filtrate merges three times decocts 10 minutes again, adds bulk drug and indigo naturalis obtained by step (1)-(3), fully
Stir and decoct, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
Model case two：Poplar XX, man, 45 years old, Jining of Shandong Province Qufu personage.Symptom：Operation for cervical carcinoma is followed by by radiotherapy in the treatment,
In 4th week of radiotherapy, there is bloody stool, stomachache, diarrhoea, the malaise symptoms of malaise, go examination in hospital visible under proctoscope
Intestinal wall is congested, and doctor, which gives, takes hemostatic and antiphlogistic treatment, Relapse rate, goes examination in hospital to be diagnosed as exedens rectum
Inflammation, it is fine to hear of Chinese medicine preparation curative effect of the present invention.
Using and using the gained Chinese medicine preparation of embodiment 2, simultaneously oral medication 1 day, malaise symptoms mitigate, are continuing with bowel lavage
Chinese medicine preparation treatment of the present invention 7 days, clinical symptoms are wholly absent, after half a year follow-up do not recur again.
Embodiment 3 treats the Chinese medicine preparation of proctitis ulcerosa, takes the primary raw material of following weight proportions to be prepared (often
Part takes 10g)：5 parts of cuttlebone, 16 parts of the root bark of shaggy-fruited dittany, 15 parts of myrrh, 4 parts of Chinese gall, 4 parts of cow-bezoar, 8 parts of keel, 9 parts of indigo naturalis, Poria cocos
12 parts, 14 parts of pappy shell, 6 parts of wrinkled giant hyssop, 3.5 parts of borneol, 6 parts of Radix Angelicae Sinensis, rhizoma polygoni paleacei 20-38 parts, 15 parts of Hericium erinaceus, 5 parts of the Radix Astragali, trifoliate orange
It is real 13 parts, 10 parts of radish.
The Chinese medicine preparation of rectitis is treated, preparation process is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1.3 hours, sesame oil is instilled, then
It is secondary to decoct 5 minutes, wait to decoct well-done cuttlebone, keel and pappy shell and be placed on food steamer to steam 15 minutes, taking-up frying is crisp, grinding
It is stand-by into smalls；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Rice vinegar is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into crock while hot
It is interior, close the lid, boil in a covered pot over a slow fire 14 hours, take the hot pot dryouied, ready-mixed oil is added, when hot pot surrounding has blue or green cigarette to emerge, by what is boiled in a covered pot over a slow fire
Chinese medicine is immediately placed in pot, frying 5 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in light-coloured vinegar and soaks 3.5 hours, is placed on food steamer and steams 45 minutes, with big
Iron spoon is ground into thick liquid, and thick liquid is dried 13 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, the water of 2.5 times of first time plus raw material weight, decoct 25 minutes, filtering, obtain filtrate 1, add 3.5 times of filter residue weight for the second time
Water, intense fire are fried open, and are turned to be cooked by slow fire 1 hour, are filtered, and obtain 1.5 times of water of filtrate 2, third time plus filter residue weight, and culture decocts
13 minutes, filtering, filtrate 3 is obtained, filtrate merges three times decocts 10 minutes again, adds bulk drug and green grass or young crops obtained by step (1)-(3)
Black pigment used by women in ancient times to paint their eyebrows, it is sufficiently stirred and decocts, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
Embodiment 4 treats the Chinese medicine preparation of proctitis ulcerosa, takes the primary raw material of following weight proportions to be prepared (often
Part takes 10g)：9 parts of cuttlebone, 25 parts of the root bark of shaggy-fruited dittany, 25 parts of myrrh, 8 parts of Chinese gall, 8 parts of cow-bezoar, 13 parts of keel, 11 parts of indigo naturalis, Fu
18 parts of Siberian cocklebur, 18 parts of pappy shell, 8 parts of wrinkled giant hyssop, 5 parts of borneol, 14 parts of Radix Angelicae Sinensis, 38 parts of rhizoma polygoni paleacei, 28 parts of Hericium erinaceus, 7 parts of the Radix Astragali, the dried immature fruit of citron orange
18 parts, 14 parts of radish.
The Chinese medicine preparation of rectitis is treated, preparation process is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1.8 hours, sesame oil is instilled, then
It is secondary to decoct 5 minutes, wait to decoct well-done cuttlebone, keel and pappy shell and be placed on food steamer to steam 25 minutes, taking-up frying is crisp, grinding
It is stand-by into smalls；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Rice vinegar is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into crock while hot
It is interior, close the lid, boil in a covered pot over a slow fire 15 hours, take the hot pot dryouied, ready-mixed oil is added, when hot pot surrounding has blue or green cigarette to emerge, by what is boiled in a covered pot over a slow fire
Chinese medicine is immediately placed in pot, frying 7 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in light-coloured vinegar and soaks 4.5 hours, is placed on food steamer and steams 55 minutes, with big
Iron spoon is ground into thick liquid, and thick liquid is dried 18 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, the water of 3.5 times of first time plus raw material weight, decoct 35 minutes, filtering, obtain filtrate 1, add 4.5 times of filter residue weight for the second time
Water, intense fire are fried open, and are turned to be cooked by slow fire 1 hour, are filtered, and obtain 2.5 times of water of filtrate 2, third time plus filter residue weight, and culture decocts
18 minutes, filtering, filtrate 3 is obtained, filtrate merges three times decocts 10 minutes again, adds bulk drug and green grass or young crops obtained by step (1)-(3)
Black pigment used by women in ancient times to paint their eyebrows, it is sufficiently stirred and decocts, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
Embodiment 5 treats the Chinese medicine preparation of proctitis ulcerosa, takes the primary raw material of following weight proportions to be prepared (often
Part takes 10g)：8 parts of cuttlebone, 20 parts of the root bark of shaggy-fruited dittany, 20 parts of myrrh, 6 parts of Chinese gall, 5 parts of cow-bezoar, 10 parts of keel, 10 parts of indigo naturalis, Fu
15 parts of Siberian cocklebur, 15 parts of pappy shell, 7 parts of wrinkled giant hyssop, 4 parts of borneol, 12 parts of Radix Angelicae Sinensis, 30 parts of rhizoma polygoni paleacei, 25 parts of Hericium erinaceus, 6 parts of the Radix Astragali, the dried immature fruit of citron orange
15 parts, 12 parts of radish.
The Chinese medicine preparation of rectitis is treated, preparation process is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1.5 hours, sesame oil is instilled, then
It is secondary to decoct 5 minutes, wait to decoct well-done cuttlebone, keel and pappy shell and be placed on food steamer to steam 20 minutes, taking-up frying is crisp, grinding
It is stand-by into smalls；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated,
Rice vinegar is added, has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into crock while hot
It is interior, close the lid, boil in a covered pot over a slow fire 14.5 hours, take the hot pot dryouied, add ready-mixed oil, when hot pot surrounding has blue or green cigarette to emerge, will boil in a covered pot over a slow fire
Chinese medicine be immediately placed in pot, frying 6 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in light-coloured vinegar and soaks 4 hours, is placed on food steamer and steams 50 minutes, with big iron
Spoon is ground into thick liquid, and thick liquid is dried 15 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, three are decocted
It is secondary, the water of 3 times of first time plus raw material weight, decoct 30 minutes, filtering, obtain filtrate 1, second of the water for adding 4 times of filter residue weight is military
Fire is fried open, and is turned to be cooked by slow fire 1 hour, is filtered, and obtains 2 times of water of filtrate 2, third time plus filter residue weight, and culture decocts 15 minutes,
Filtering, obtains filtrate 3, and filtrate merges three times decocts 10 minutes again, adds bulk drug and indigo naturalis obtained by step (1)-(3), fully
Stir and decoct, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
Experimental example：1st, selection of clinical：In order to verify the effect of Chinese medicine composition of the present invention, we have extracted 400 patients
The experiment of medicine has been carried out, has been equally divided into two groups, experimental group and control group.
2nd, inclusion criteria：Through being diagnosed as proctitis ulcerosa patient, there are proctitis ulcerosa clinical symptoms one or more.
3rd, treatment method：Prepared Chinese medicine preparation using when be divided into two, portion washed open with hot water, be put into clean container
Interior use is used as enema, and another uses taken with boiled water.
4th, curative effect situation criterion：1st, cure.After medicine, malaise symptoms are wholly absent；2nd, effectively.Use medicine
Afterwards, malaise symptoms mitigation or partial disappearance；3rd, it is invalid.After medicine, malaise symptoms are unchanged.We conducted the reality of medicine
Test (embodiment 5), and statistics and mathematical analysis accurately have been carried out to data.
Specific experiment result such as following table：
Table 1：
Clinical tests prove that controlled using Chinese medicine preparation of the present invention compared with the means of western medical treatment proctitis ulcerosa
Recurrence rate after healing is low, and treatment means are more fully thorough, has no side effect during use, while proctitis ulcerosa is treated,
The clinical symptoms such as the bloody stool brought by rectitis, diarrhoea, stomachache, tenesmus, anus cusalgia pendant pain can be alleviated.Tried through clinic
Verify bright, efficient Chinese drugs agentia of the present invention is 99%, is the Chinese medicine preparation commonly used in clinical care.
Claims (9)
1. treat the preparation method of the Chinese medicine preparation of proctitis ulcerosa, it is characterised in that：Take the raw material system of following weight proportions
It is standby to form：Cuttlebone 5-9 parts, root bark of shaggy-fruited dittany 16-25 parts, myrrh 15-25 parts, Chinese gall 4-8 parts, cow-bezoar 4-8 parts, keel 8-13
Part, indigo naturalis 9-11 parts, Poria cocos 12-18 parts, pappy shell 14-18 parts, wrinkled giant hyssop 6-8 parts, borneol 3.5-5 parts, Radix Angelicae Sinensis 6-14 parts, careless blood
Exhaust 20-38 parts, Hericium erinaceus 15-28 parts, Radix Astragali 5-7 parts, dried immature fruit of citron orange 13-18 parts, radish 10-14 parts；Step is as follows：
1. cuttlebone, keel and pappy shell are placed in clean container, after adding water to cook 1.3-1.8 hours, sesame oil is instilled, then
It is secondary to decoct 5 minutes, wait that decocting well-done cuttlebone, keel and pappy shell is placed in steaming 10-30 minutes on food steamer, taking-up frying is crisp,
It is stand-by to be ground into smalls；
2. the root bark of shaggy-fruited dittany, myrrh, Chinese gall and cow-bezoar are cleaned, drain away the water, be cut into silk, be placed in crock, pot is heated, add
Vinegar, it has been heated to adding white sugar when hot gas is blown out, white sugar is stirred to complete with iron spoon and melted, is poured into while hot in crock,
Close the lid, boil in a covered pot over a slow fire 14-15 hours, take the hot pot dryouied, ready-mixed oil is added, when hot pot surrounding has blue or green cigarette to emerge, by what is boiled in a covered pot over a slow fire
Chinese medicine is immediately placed in pot, frying 5-7 minutes, it is stand-by to be ground into smalls；
3. by radish peeled wash, block is cut into, is placed in immersion 3.5-4.5 hours in light-coloured vinegar, is placed in steaming 45-55 minutes on food steamer,
Thick liquid is ground into big iron spoon, thick liquid is dried into 10-20 minutes, obtains drying object；
4. Poria cocos, wrinkled giant hyssop, borneol, Radix Angelicae Sinensis, rhizoma polygoni paleacei, Hericium erinaceus, the Radix Astragali and the dried immature fruit of citron orange are together placed in marmite, decoct three times,
Add the water of 2.5-3.5 times of raw material weight for the first time, decoct 25-35 minutes, filtering, obtain filtrate 1, second plus filter residue weight 3.5-
4.5 times of water, intense fire are fried open, and are turned to be cooked by slow fire 1 hour, are filtered, obtain 1-3 times of water of filtrate 2, third time plus filter residue weight,
10-20 minutes are cooked by slow fire, filters, obtains filtrate 3, filtrate merges three times decocts 10 minutes again, adds step（1）-（3）Gained
Bulk drug and indigo naturalis, it is sufficiently stirred and decocts, when filtrate is concentrated into the 1/2 of original volume, ceases fire, bottle and produce.
2. preparation method according to claim 1, it is characterised in that：Each raw material is as follows：Take the main of following weight proportions
Raw material is prepared：8 parts of cuttlebone, 20 parts of the root bark of shaggy-fruited dittany, 20 parts of myrrh, 6 parts of Chinese gall, 5 parts of cow-bezoar, 10 parts of keel, indigo naturalis 10
Part, 15 parts of Poria cocos, 15 parts of pappy shell, 7 parts of wrinkled giant hyssop, 4 parts of borneol, 12 parts of Radix Angelicae Sinensis, 30 parts of rhizoma polygoni paleacei, 25 parts of Hericium erinaceus, the Radix Astragali 6
Part, 15 parts of the dried immature fruit of citron orange, 12 parts of radish.
3. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：1. step adds water to cook 1.5 hours
Afterwards, sesame oil is instilled, is decocted 5 minutes again.
4. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：Step is 2. by the root bark of shaggy-fruited dittany, myrrh, five
Gall nut and cow-bezoar are cleaned, and are drained away the water, and are cut into silk, are placed in crock, and pot is heated, and add rice vinegar.
5. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：2. step is boiled in a covered pot over a slow fire 14.5 hours.
6. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：Step is 2. fast by the Chinese medicine boiled in a covered pot over a slow fire
Speed is placed in pot, frying 6 minutes.
7. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：3. step is placed in light-coloured vinegar soaks 4
Hour, it is placed on food steamer and steams 50 minutes.
8. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：4. step adds raw material weight for the first time
3 times of water, decoct 30 minutes.
9. the preparation method of Chinese medicine preparation according to claim 1, it is characterised in that：4. step adds filter residue weight second
4 times of water.
Priority Applications (1)
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Denomination of invention: Traditional Chinese medicine preparations and their preparation methods for treating ulcerative proctitis Effective date of registration: 20231231 Granted publication date: 20180112 Pledgee: Bank of China Limited by Share Ltd. Zhangpu branch Pledgor: TONGYITANG PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980075812 |
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