CN104983939A - Traditional Chinese medicine for treating arteriosclerosis obliterans - Google Patents
Traditional Chinese medicine for treating arteriosclerosis obliterans Download PDFInfo
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- CN104983939A CN104983939A CN201510403918.5A CN201510403918A CN104983939A CN 104983939 A CN104983939 A CN 104983939A CN 201510403918 A CN201510403918 A CN 201510403918A CN 104983939 A CN104983939 A CN 104983939A
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Abstract
The invention relates to a traditional Chinese medicine for treating arteriosclerosis obliterans. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 6 parts of lopseed, 12 parts of lycopodium calvatum, 12 parts of radix angelicae lateralis preparata, 9 parts of loofah sponge, 9 parts of madder, 6 parts of radix ampelopsis, 9 parts of large-leaved gentian and 1 part of momordica cochinchinensis. Clinic experiments prove that the traditional Chinese medicine can be used for safely and effectively treating the arteriosclerosis obliterans.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of arteriosclerosis obliterans.
Background technology
Arteriosclerosis obliterans is that generalized atherosclerosis is in limbs topical manifestations, be systemic artery inner membrance and middle level thereof be degeneration, Hypertrophic change, make blood vessel wall hardening, reduce, follow the string, thus secondary thrombus is formed, cause Distal blood flow amount Progressive symmetric erythrokeratodermia to reduce or interrupt.The each major arteries of whole body can be betided, be more common in the large of ventral aorta lower end and lower limb, medium-sized artery.The ventral aorta and the two common iliac artery persons that occur in below renal artery are called Leriche syndrome.For the arteriosclerosis patient in mid-term, the clinical symptoms such as Most patients all more or less listless and aching, the limping of had palpitation, nervous, chest pain, uncomfortable in chest, headache, dizziness, the cool fiber crops of extremity, extremity, vision reduction, hypomnesis, insomnia, dreaminess.
Medical material present Research involved in the present invention is as follows:
The herb of Herba speranskiae tuberculatae [another name] [source] Euphorbiaceae Speranskia plant speranskia tuberculata, Balsaminaceae herbaceous plant Flos Impatientis, Bignoniaceae Incarvillea AJuss plant Herba Incarvilleae sinensis, pulse family Vetch plant Herba Viciae Amoenae and the Herb of Ericaceae Gaultheria plant Caulis et folium gaultheriae yunnanensis.Xia Qiucai.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, kidney channel.[function cures mainly] expelling wind and removing dampness, removing toxic substances pain relieving.For rheumatic arthritis; Sore swollen toxin is controlled in external.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] is not taken by pregnant women.[extracts] " China's book on Chinese herbal medicine ".
Herba Lycopodii [another name] Lycopodium clavatum, lion tail, lion grass, green hair are stretched muscle, are littlely stretched muscle, Lycopodium casuarinoides Spring.[source] this product is the dry herb of lycopsid Lycopodium clavatum.Summer, autumn two gather when season, stem and leaf was luxuriant, and removing impurity, dries.[nature and flavor] micro-hardship, pungent, temperature.[return through] returns liver,spleen,kidney warp.[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For joint aches, joint stuffiness.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.[attention] " anemia of pregnant woman and Massive Bleeding person avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Radix Angelicae Sinensis [another name] Radix Angelicae Sinensis, Radix Angelicae Sinensis, return and must, return lower limb, slightly return lower limb.The supporting root of [source] umbelliferae angelica.[nature and flavor] are pungent, sweet, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] dampness fullness in the epigastrium and abdomen and the careful clothes of diarrhea with loose stool person.[extracts] " China's book on Chinese herbal medicine ".
Retinervus Luffae Fructus [another name] Fructus Luffae net, Fructus Luffae shell, melon network, wadding melon pulp, sky sieve line, vegetable sponge, chalina, Hypericum perforatum L..[source] this product is the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae.Summer, season in autumn two fruit maturation, peel turns yellow, inner withered time pluck, removing crust and sarcocarp, clean, dry, removing seed.[nature and flavor] are sweet, flat.[return through] returns lung, stomach, Liver Channel.[function cures mainly] dredging collateral, invigorates blood circulation, dispels the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Radix Rubiae [another name] Galium spurium L., uproot plants after their edible portions have been harvested, HUOXUECAO, red Radix Rubiae, carriage, extension draw bean, red line grass, Radix seu Caulis Schisandrae Sinensis, Herba Chenopodii Hybridi.[source] this product is the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae.Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are bitter, cold.[return through] returns Liver Channel.[function cures mainly] removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.[usage and dosage] takes orally: decoct soup, 6 ~ 9g.[attention] Deficiency and coldness of spleen and stomach and without the careful clothes of the stagnant person of the stasis of blood.[extracts] " China's book on Chinese herbal medicine ".
Radix Ampelopsis [another name] mountain region melon, wild Radix Ipomoeae, Vitis Amurensis seedling, Bletilla striata (Thunb.ex A.Murray)Rchb.f., Herba Rubi blinii.[source] this product is the dried root of vitaceae Radix Ampelopsis.Spring, Qiu Erji excavate, and removing silt and radicula, be cut into vertical lobe or inclined tab, dry.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.For carbuncle carbuncle on the back, furuncle, scrofula, burn due to hot liquid or fire.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] should not with Aconitum medical material with using.[extracts] " China's book on Chinese herbal medicine ".
Radix Gentianae Macrophyllae [another name] gentiana straminea, Gentiana dahurica, Radix Gentianae Marcrophyllae, western Radix Gentianae Marcrophyllae, a left side are turned round, a left side is twisted, RADIX GENTIANAE MACROPHYLLAE, RADIX GENTIANAE MACROPHYLLAE, Radix Raphani Macrophylla, plait Macrophylla.[source] this product is the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.First three kind practises title " Radix Gentianae Macrophyllae " and " gentiana straminea " respectively by character difference, and rear one is practised and claimed " Gentiana dahurica ".Spring, Qiu Erji excavate, removing silt; Radix Gentianae Macrophyllae and gentiana straminea shine soft, bank up " diaphoresis " to surface in reddish yellow or lark time, spread out and dry, or directly dry without " diaphoresis "; Rub de-black skin with the hands when Gentiana dahurica is taken advantage of fresh, dry.[nature and flavor] are pungent, bitter, flat.[return through] returns stomach, liver, gallbladder meridian.[function cures mainly] wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, and infantile malnutrition generates heat.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] be pain weakness with emaciation for a long time, and frequent micturition, just sliding person avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Semen Momordicae [another name] rattan paulownia, Semen Momordicae, leakage Siberian cocklebur.[source] this product is the dry mature seed of cucurbitaceous plant Semen Momordicae.To gather winter mature fruit, cut open, shine to half-dried, removing sarcocarp, takes out seed, dry.[nature and flavor] are bitter, micro-sweet, cool.[return through] returns liver, spleen, stomach warp.[function cures mainly] mass dissipating and swelling eliminating, counteracting toxic substances treats skin ulcer.For sore swollen toxin, acute mastitis, scrofula, anal fistula, chronic eczema, tinea alba.[usage and dosage] takes orally: decoct soup, 0.9 ~ 1.2g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of arteriosclerosis obliterans, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing arteriosclerosis obliterans.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of arteriosclerosis obliterans, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba speranskiae tuberculatae 6 parts, Herba Lycopodii 12 parts, Radix Angelicae Sinensis 12 parts, Retinervus Luffae Fructus 9 parts, 9 parts, Radix Rubiae, Radix Ampelopsis 6 parts, Radix Gentianae Macrophyllae 9 parts, Semen Momordicae 1 part.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and arteriosclerosis obliterans patient 96 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 48 example and matched group 48 example at random, treatment group man 29 example, female 19 example, 68.4 years old mean age; Matched group man 31 example, female 17 example, 73.5 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national arteriosclerosis obliterans's clinical speciality: (1) is numb, be afraid of cold (or scorching hot), intermittent limping, congestion, malnutrition changes, and even ulcer or gangrene occurs, normal extremity morbidity, attach most importance to lower limb, have 20% ~ 25% acute arterial embolism or artery thrombosis occur.(2). suffering limb proximal part has systole vascular murmur.(3). various Inspection Certificate, has limb artery stenosis occlusion to sexually revise, lower limb rouge, and the above pathological changes of femoral artery is commonly (often involve limbs large, medium-sized artery.(4). normal with hypertension, coronary heart disease, hyperlipemia, diabetes, the diseases such as cerebrovascular arteries sclerosis.(5). get rid of thromboangiitis obliterans, Takayasu arteritis, raynaud disease, other ischemic disease of limb such as Cold water stress angiopathy.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 2 times.8 weeks courses for the treatment of.
The oral cilostazol 100mg of matched group, 2 times/day.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: 1. clinical symptoms disappears substantially; 2. limbs wound surface heals completely; 3. distal limb disturbance of blood circulation and rheography obviously change; 4. walking speed 100 ~ 120 steps/rain, can continue walking about 1 about 000m.；
Effective: 1. clinical symptoms is obviously improved; 2. limbs wound healing or close healing: 3. distal limb disturbance of blood circulation and rheography are all improved: 4. walking speed 100 ~ 120 steps/min.Walking about 500m can be continued.
Effective: 1. clinical symptom relief; 2. limbs wound surface is close to healing or reducing; 3. distal limb disturbance of blood circulation and rheography are all improved; 4. walking speed 100 ~ 120 steps/min. can continue walking about 300m.
Invalid: after treating 1 course for the treatment of, symptom and sign continue development person without improvement or the state of an illness.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment arteriosclerosis obliterans, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba speranskiae tuberculatae 6 grams, Herba Lycopodii 12 grams, Radix Angelicae Sinensis 12 grams, Retinervus Luffae Fructus 9 grams, 9 grams, Radix Rubiae, Radix Ampelopsis 6 grams, Radix Gentianae Macrophyllae 9 grams, Semen Momordicae 1 gram; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis obliterans.Oral, every bu is taken for twice sooner or later.
Embodiment 2
Take: Herba speranskiae tuberculatae 6 grams, Herba Lycopodii 12 grams, Radix Angelicae Sinensis 12 grams, Retinervus Luffae Fructus 9 grams, 9 grams, Radix Rubiae, Radix Ampelopsis 6 grams, Radix Gentianae Macrophyllae 9 grams, Semen Momordicae 1 gram; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis obliterans.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Take: Herba speranskiae tuberculatae 6 grams, Herba Lycopodii 12 grams, Radix Angelicae Sinensis 12 grams, Retinervus Luffae Fructus 9 grams, 9 grams, Radix Rubiae, Radix Ampelopsis 6 grams, Radix Gentianae Macrophyllae 9 grams, Semen Momordicae 1 gram; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis obliterans.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of arteriosclerosis obliterans, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba speranskiae tuberculatae 6 parts, Herba Lycopodii 12 parts, Radix Angelicae Sinensis 12 parts, Retinervus Luffae Fructus 9 parts, 9 parts, Radix Rubiae, Radix Ampelopsis 6 parts, Radix Gentianae Macrophyllae 9 parts, Semen Momordicae 1 part.
2. as claimed in claim 1 for the Chinese medicine of arteriosclerosis obliterans, it is characterized in that, its preparation method is: take: Herba speranskiae tuberculatae 6 parts, Herba Lycopodii 12 parts, Radix Angelicae Sinensis 12 parts, Retinervus Luffae Fructus 9 parts, 9 parts, Radix Rubiae, Radix Ampelopsis 6 parts, Radix Gentianae Macrophyllae 9 parts, Semen Momordicae 1 part; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of arteriosclerosis obliterans as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba speranskiae tuberculatae 6 parts, Herba Lycopodii 12 parts, Radix Angelicae Sinensis 12 parts, Retinervus Luffae Fructus 9 parts, 9 parts, Radix Rubiae, Radix Ampelopsis 6 parts, Radix Gentianae Macrophyllae 9 parts, Semen Momordicae 1 part; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of arteriosclerosis obliterans as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba speranskiae tuberculatae 6 parts, Herba Lycopodii 12 parts, Radix Angelicae Sinensis 12 parts, Retinervus Luffae Fructus 9 parts, 9 parts, Radix Rubiae, Radix Ampelopsis 6 parts, Radix Gentianae Macrophyllae 9 parts, Semen Momordicae 1 part; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN106421195A (en) * | 2016-10-20 | 2017-02-22 | 张微 | Traditional Chinese medicine for treating arteriosclerotic occlusion |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104906272A (en) * | 2015-07-03 | 2015-09-16 | 梁立周 | Medicine for treating arteriolar nephrosclerosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104906272A (en) * | 2015-07-03 | 2015-09-16 | 梁立周 | Medicine for treating arteriolar nephrosclerosis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421195A (en) * | 2016-10-20 | 2017-02-22 | 张微 | Traditional Chinese medicine for treating arteriosclerotic occlusion |
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Application publication date: 20151021 |