CN104606549A - Traditional Chinese medicine for treating viral myocarditis - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating viral myocarditis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 8 parts of allium macrostemon, 6 parts of aster, 10 parts of trichosanthes kirilowii maxim, 8 parts of blackberry lily, 3 parts of puffball and 6 parts of caulis bambusae in taeniam. The clinical experiment proves that the traditional Chinese medicine can be used for safely and effectively treating the viral myocarditis.

Description

A kind of Chinese medicine being used for the treatment of viral myocarditis

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of viral myocarditis.

Background technology

Viral myocarditis refers to the myocardium limitation that viral infection causes or diffuse acute or chronic inflammatory conditions, belongs to infectious cardiomyopathy.About there is 5% patient that myocarditis occurs in viral prevalence infection period, also can be dispersed in morbidity.Clinical manifestation weight is different.Infect medical history according to typical forerunner, corresponding clinical manifestation, the myocardial damage evidence of electrocardiogram, myocardial injury markers, ultrasonic cardiography display considers this diagnosis, makes a definite diagnosis and depends on endomyocardial biopsy.Current without specificity therapeutic method, treat mainly for viral infection and myocardial inflammation.Most patients recovery from illness after suitable treatment, only a few patient in acute stage because severe arrhythmia, acute heart failure and cardiogenic shock are dead.Some patients can develop into dilated cardiomyopathy.

Primary disease any age all can fall ill, but common with teenager, and male is more than women, and summer and autumn is season occurred frequently.Primary disease obstinate easily leaves sequela.

Viral myocarditis morbidity is anxious, its pathogeny mostly is viral infection, current without specific treatment, treatment is mainly for viral infection and myocardial inflammation, can vein or oral vitamin C, coenzyme Q10, folic acid o, ATP, inosine, cyclic adenosine monophosphate (cAMP), cytochrome C, Radix Salviae Miltiorrhizae etc., but its therapeutic effect is all undesirable and side effect is larger.

Primary disease belongs to the category such as the traditional Chinese medical science " cardiopalmus ", " thoracic obstruction ", " edema ", " palpitation with a distress feeling ", " asthenia " according to its clinical manifestation.

Medical material present Research involved in the present invention is as follows:

Bulbus Allii Macrostemonis [source] this product is the dry bulb of liliaceous plant Allium macrostemon Allium macrostemon Bge. or Chinese onion Allium chinensis G.Don.Summer, Qiu Erji excavate, and clean, removing fibrous root, steam thoroughly or put in boiling water and scald thoroughly, dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns lung, stomach, large intestine channel.[function cures mainly] activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For thoracic obstruction pain, phlegm retention cough with asthma is heavy after letting out dysentery.[usage and dosage] 5 ~ 9g.

Radix Asteris [source] this product is the dry root and rhizome of feverfew Radix Asteris Aster tataricus L.f..Spring, Qiu Erji excavate, and removing has the rhizome of joint (practise and claim " parent root ") and silt, weaves into pigtail and dries, or directly dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns lung meridian.[function cures mainly] nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.[usage and dosage] 5 ~ 9g.

Fructus Trichosanthis [source] this product is the dry mature fruit of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosan-thes rosthornii Harms.During fruit maturation in autumn, connect carpopodium and cut, put ventilation and dry in the shade.[nature and flavor] sweet, micro-hardship, cold.[return through] returns lung, stomach, large intestine channel.[function cures mainly] clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.[usage and dosage] 9 ~ 15g.[attention] should not with Aconitum medical material with using.

Rhizoma Belamcandae [source] this product is the dry rhizome of irides Rhizoma Belamcandae Belamcanda chinensis (L.) DC..Just germinateed at the beginning of spring or autumn Mo, stem and leaf was withered time excavate, removing fibrous root and silt, drying.[nature and flavor] are bitter, cold.[return through] returns lung meridian.[function cures mainly] heat-clearing and toxic substances removing, expectorant, sore-throat relieving.For the pent-up of pyretic toxicity phlegm-fire, laryngopharynx swelling and pain, accumulation and obstruction of sputum, cough and asthma.[usage and dosage] 3 ~ 9g.

Lasiosphaera Seu Calvatia [source] is the nearly mature sporophore of Hui Bao section lasiosphaera fenzlii Reics platymiscium lasiosphaera fenzlii Reics Lasiosphaera fenzliiReich., Lycoperdon plant calvatia gigantea Calvatia gigantea (Batach.ex Pers.) Lloyd. and purple Lasiosphaera Seu Calvatia C.lilacina Lloyd..Autumn gathers when sporophore is just ripe, removes silt, dries.[nature and flavor] are pungent, flat.[function cures mainly] heat clearing away, sore-throat relieving, hemostasis.Cure mainly: pharyngolaryngitis, tonsillitis; Traumatic hemorrhage is controlled in external, bleeding hemorrhoids chilblain.[usage and dosage] 1.5 ~ 6g.

Caulis Bambusae In Taenia [source] this product is the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro Bambusa tuldoides Munro, major part allusion quotation bamboo Sinocalamus beecheyanus (Munro) Mc-Clure var.pubescens P.F.Li or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle Phyllostachys nigra (Lodd.) Munro var.henonis (Mitf.) Stapf exRendle.The whole year all can gather and process, and gets fresh stem, and removing crust, spreads to strand by slightly viridant intermediate layer, or chip, tie up bunchy, dry in the shade.The former claims " loose Caulis Bambusae In Taenia ", and the latter claims " neat Caulis Bambusae In Taenia ".[nature and flavor] are sweet, are slightly cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] removing heat-phlegm, relieves restlessness and prevents vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, and eye is lost in palpitation with fear, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.[usage and dosage] 4.5 ~ 9g.

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of viral myocarditis, by selecting suitable medical material and proportioning thereof, reaches the myocarditic object of safe and effective Cure Viruses.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a Chinese medicine for viral myocarditis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Bulbus Allii Macrostemonis 8 parts, Radix Asteris 6 parts, Fructus Trichosanthis 10 parts, Rhizoma Belamcandae 8 parts, Lasiosphaera Seu Calvatia 3 parts, Caulis Bambusae In Taenia 6 parts.

Though inventor thinks that the myocarditic cause of disease has exopathogen to invade, unhygienic diet, overfatigue, feelings will is unsuccessful, is mainly the evil poison of diseases caused by exogenous pathogenic factor, caused by interior house pericardium.Pathological change is that warm poison is evil, and attack and defend in lung, good and evil are handed over and striven, and positive exogenous pathogen enters, interior house pericardium, invade heart arteries and veins, cause the painstaking effort stasis of blood stagnant, and see the diseases such as feeling of oppression and pain in the chest, cardiopalmus are out of breath, irregularly intermittent and regularly intermittent pulse.Or the heresy of severe pathogenic cold, stagnate heart arteries and veins, and resistance numbness painstaking effort are run, and cause uncomfortable in chest, slow pulse; Evil sad sun, edema due to YANG-insufficiency, the heart attacked by pathogenic water is surveyed and is seen that cardiopalmus is panted, and limb is swollen waits disease.Or this phlegm-damp is for suffering from, the heart invaded by re-heat poison, ties mutually with disease, stasis blocking heart arteries and veins and see day greasy bitter taste, and pain is suppressed in ambition.With the passing of time heresy is checked, and its gesture is slow, deficiency of both QI and YIN, lack of preservation of spirit, then Mental fatigue, cardiopalmus severe palpitation, dysphoria with feverish sensation in the chest palms and soles, irregularly intermittent and regularly intermittent pulse etc.; Gas sun two is empty, and arteries and veins loses agitates survey uncomfortable in chest, dizzy, slow pulse.Treatment should clear away heart-fire with removing toxic substances, cold relieving by heresy, replenishing vital QI with drugs of warm nature heart arteries and veins, reinforce functional activities of the heart, the temperature heart-yang that shakes is basic, therefore assembly is our.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Inventor in February, 2011 ~ within 2013, collect outpatient service between JIUYUE altogether and Patients with Viral Myocarditis 68 example of being in hospital, be divided into treatment group 32 example and matched group 36 example at random, treatment group man 19 example, female 13 example, 30 ~ 71 years old age, 47.4 years old mean age, the course of disease 1 ~ 10 year; Matched group man 23 example, female 13 example, 32 ~ 72 years old age, 48.9 years old mean age, the course of disease 1 ~ 8 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

1) functional defect, cardiogenic shock or cardio-cerebral syndrome; 2) cardiac dilatation.X-ray, echocardiography have one of performance; 3) ECG change: during I, II, aVF, V5 lead, more than 2 or 2 ST-T change and continue more than 4 days, and other severe arrhythmias; 4) CK-MB raises, and cardiac troponin (cTnI or cTnT) is positive.Possess 2 in above-mentioned 4 and can make a definite diagnosis primary disease.

2, test method

2.1 Therapeutic Method

The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.12 weeks courses for the treatment of.

The oral coenzyme-Q _10 tablet of matched group (Shanghai Sine Pharmaceutical Co., Ltd.), takes according to its description.12 weeks courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Cure: subjective symptoms disappears, electrocardiogram, rabat, myocardial enzymes recover normal;

Effective: to have following more than two persons, subjective symptoms disappears, and myocardial enzymes is close to normal, and electrocardiogram is normal;

Invalid: subjective symptoms is without alleviation, and electrocardiogram, myocardial enzymes, rabat are not improved compared with before treatment.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment viral myocarditis, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Specific embodiment 1

Take: Bulbus Allii Macrostemonis 8 grams, Radix Asteris 6 grams, Fructus Trichosanthis 10 grams, Rhizoma Belamcandae 8 grams, Lasiosphaera Seu Calvatia 3 grams, Caulis Bambusae In Taenia 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of viral myocarditis.Oral, every bu morning, noon and afternoon take for three times.

Specific embodiment 2

Take: Bulbus Allii Macrostemonis 8 grams, Radix Asteris 6 grams, Fructus Trichosanthis 10 grams, Rhizoma Belamcandae 8 grams, Lasiosphaera Seu Calvatia 3 grams, Caulis Bambusae In Taenia 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of viral myocarditis.Oral, daily once.

Specific embodiment 3

Take: Bulbus Allii Macrostemonis 8 grams, Radix Asteris 6 grams, Fructus Trichosanthis 10 grams, Rhizoma Belamcandae 8 grams, Lasiosphaera Seu Calvatia 3 grams, Caulis Bambusae In Taenia 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of viral myocarditis.Oral, every bu is taken for twice sooner or later.

Claims (4)

1. be used for the treatment of a Chinese medicine for viral myocarditis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Bulbus Allii Macrostemonis 8 parts, Radix Asteris 6 parts, Fructus Trichosanthis 10 parts, Rhizoma Belamcandae 8 parts, Lasiosphaera Seu Calvatia 3 parts, Caulis Bambusae In Taenia 6 parts.

2. a kind of Chinese medicine being used for the treatment of viral myocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: Bulbus Allii Macrostemonis 8 parts, Radix Asteris 6 parts, Fructus Trichosanthis 10 parts, Rhizoma Belamcandae 8 parts, Lasiosphaera Seu Calvatia 3 parts, Caulis Bambusae In Taenia 6 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. a kind of Chinese medicine being used for the treatment of viral myocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: Bulbus Allii Macrostemonis 8 parts, Radix Asteris 6 parts, Fructus Trichosanthis 10 parts, Rhizoma Belamcandae 8 parts, Lasiosphaera Seu Calvatia 3 parts, Caulis Bambusae In Taenia 6 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. a kind of Chinese medicine being used for the treatment of viral myocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: Bulbus Allii Macrostemonis 8 parts, Radix Asteris 6 parts, Fructus Trichosanthis 10 parts, Rhizoma Belamcandae 8 parts, Lasiosphaera Seu Calvatia 3 parts, Caulis Bambusae In Taenia 6 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.