CN104623279A - Traditional Chinese medicine for treating coronary heart disease - Google Patents

Traditional Chinese medicine for treating coronary heart disease Download PDF

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CN104623279A
CN104623279A CN201510055631.8A CN201510055631A CN104623279A CN 104623279 A CN104623279 A CN 104623279A CN 201510055631 A CN201510055631 A CN 201510055631A CN 104623279 A CN104623279 A CN 104623279A
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heart disease
coronary heart
chinese medicine
treatment
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徐鸿刚
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Abstract

The invention relates to a traditional Chinese medicine for treating coronary heart disease. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 3 parts of asarum, 8 parts of allium macrostemon, 10 parts of radix polygonati officinalis, 10 parts of poria with hostwood, 12 parts of lignum dalbergiae odoriferae and 6 parts of dutchmanspipe root. The clinical experiment proves that the traditional Chinese medicine disclosed by the invention can be used for safely and effectively treating coronary heart disease.

Description

A kind of Chinese medicine being used for the treatment of coronary heart disease
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of coronary heart disease.
Background technology
Coronary atherosclerotic heart disease is coronary artery generation atherosclerotic lesion and causes lumen of vessels stenosis or occlusion, causes myocardial ischemia, anoxia or downright bad and heart disease that is that cause, is usually called as " coronary heart disease ".But the scope of coronary heart disease may be more extensive, also comprises inflammation, thromboembolism etc. and cause luminal stenosis or obturation.Coronary heart disease is divided into 5 large classes by World Health Organization (WHO): silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart desease) and sudden death 5 kinds of Clinical types.Stable coronary heart disease and acute coronary syndrome is usually divided in clinical.Clinical manifestation is typical chest pain, and because physical exertion, excited etc. is brought out, prominent sense precordialgia, mostly is ictal angor or squeezing pain, also can be sense of feeling oppressed.Pain, from after breastbone or pareordia, is upwards radiated to left shoulder, arm, even little finger of toe and the third finger, and rest or buccal nitroglycerin can be alleviated.The position that chest pain is diffused also can relate to cervical region, lower jaw, tooth, abdominal part etc.Under chest pain also can appear at rest state or night, caused by coronary spasm, also claim variant angina pectoris.As chest pain character changes, as the Progressive symmetric erythrokeratodermia chest pain recently occurred, the threshold of pain progressively declines so that pause physical exertion or excited even have a rest or sleep soundly Shi Yike outbreak.Pain is aggravated gradually, frequency conversion, duration extension, dispels inducement or buccal nitroglycerin can not be alleviated, and now often suspects unstable angina.Patient's First-episode coronary heart disease of 1/3 is about had to show as sudden death.
Primary disease any age all can fall ill, but multiple with more than 40 years old male.Primary disease complication is more and risk factor is higher.
Coronary heart disease belongs to global refractory disease, its pathogeny is completely not clear and definite so far, current western medicine has the antithrombotic reagents such as nitrate esters medicine, aspirin, clopidogrel (Plavix), fibrinolytic medicine, beta-blocker etc., but its therapeutic effect is all undesirable and side effect is larger.
Primary disease belongs to the category such as the traditional Chinese medical science " thoracic obstruction ", " chest pain ", " wholehearted sick ", " precordial pain with cold limbs " according to its clinical manifestation.
Medical material present Research involved in the present invention is as follows:
Herba Asari [source] this product is the dry herb of aristolochiaceae plant Herba Asari Asarum heterotropoides Fr.Schmidt var.mandshuricum (Maxim.) Kitag., Seoul Herba Asari Asarum sieboldii Miq.var.seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..The first two is planted to practise and claims " Herba Asari ".Summer fructescence or excavate early autumn, removing silt, dries in the shade.[nature and flavor] are pungent, temperature.[return through] GUIXIN, lung, kidney channel.[function cures mainly] expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.[usage and dosage] 1 ~ 3g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.
Bulbus Allii Macrostemonis [source] this product is the dry bulb of liliaceous plant Allium macrostemon Allium macrostemon Bge. or Chinese onion Allium chinensis G.Don.Summer, Qiu Erji excavate, and clean, removing fibrous root, steam thoroughly or put in boiling water and scald thoroughly, dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns lung, stomach, large intestine channel.[function cures mainly] activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For thoracic obstruction pain, phlegm retention cough with asthma is heavy after letting out dysentery.[usage and dosage] 5 ~ 9g.
Rhizoma Polygonati Odorati [source] this product is the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati Polygonatum odoratum (Mill.) Druce.Autumn excavates, removing fibrous root, clean, shine to softness, repeatedly rub, dry in the sun to without hard-core, dry; Or steam thoroughly, rub to translucent, dry.[nature and flavor] are sweet, are slightly cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.[usage and dosage] 6 ~ 12g.
Poria cum Radix Pini [source] this product is the natural white portion entertaining Radix Pini massonianae (i.e. Lignum Poria) in the middle of fungi plant medicine Polyporaceae plant poria cocos sclerotium.Get after Poria cuts Poria, select the person that entertains Radix Pini massonianae in the middle of Poria, removing impurity, dries.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, spleen channel.[function cures mainly] mind calming, calms the nerves, diuretic.For palpitation with fear, forgetful, forgetful insomnia, infantile convulsion, dysuria.[usage and dosage] 9 ~ 15g.
Lignum Dalbergiae Odoriferae [source] this product is the dry duramen of leguminous plant Lignum Dalbergiae Odoriferae wingceltis Dalbergia odorifera T.Chen trunk and root.The whole year all can gather, and removing sapwood, dries in the shade.[nature and flavor] are pungent, temperature.[return through] returns liver, spleen channel.[function cures mainly] promoting flow of QI and blood, pain relieving, hemostasis.For epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.[usage and dosage] 9 ~ 15g.
Radix Aristolochiae [source] this product is the dry root of aristolochiaceae plant Fructus Aristolochiae Aristolochia debilis Sieb.et Zucc..Spring, Qiu Erji excavate, and removing fibrous root and silt, dry.[nature and flavor] are pungent, bitter, cold.[return through] attaches to the lung and stomach meridians.The pain relieving of [function cures mainly] suppressing the hyperactive liver, removing toxic substances and promoting subsidence of swelling.For dizziness and headache, chest and abdomen swelling and pain, carbuncle treats skin ulcer, snake bite and insect sting.[usage and dosage] 3 ~ 9g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of coronary heart disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing coronary heart disease.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine for coronary heart disease, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Asari 3 parts, Bulbus Allii Macrostemonis 8 parts, Rhizoma Polygonati Odorati 10 parts, Poria cum Radix Pini 10 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Aristolochiae 6 parts.
Inventor thinks that coronary heart disease cause has endogenous cause of ill and therefore divides outward.Interior because worn with age, heart spleen kidney negative and positive of qi and blood is not enough; Outer finally cause painstaking effort to be run be obstructed because YIN-cold invades, diet is improper, disorder of emotion, overwork, the resistance of breast BI-syndrome involved the blood vessels and chest pain.Pathological change is worn with age, and kidney qi is empty, can not inspire heart-yang, nourish heart arteries and veins, or overstrain is pondered over, wasting QI-blood, undermines heart spleen, and insufficiency of heart-QI all can be made to lose, and the painstaking effort stasis of blood is stagnant.YIN-cold is attacked, and inside holds back breast sun, and mechanism of qi numbness hinders, and the heart arteries and veins u crapulence that stagnates is satiated with food, and taste are impaired, and transporting is unfavorable, and the turbid heap soil or fertilizer over and around the roots of expectorant is trembled with fear, blockage of the cardiac vessels.Feelings will is unsuccessful, the liver failing to maintain the normal flow of QI, qi depression to blood stasis, and heart arteries and veins is obstructed.In a word, heart spleen-kidney deficiency, negative and positive of qi and blood is not enough, is the inherent cause of disease of coronary heart disease; The pathogenic factor numbness resistance heart arteries and veins such as YIN-cold, expectorant are turbid, the stagnation of QI, blood stasis, breast sun mistake exhibition, heart arteries and veins is obstructed, stagnation of QI and blood may bring about pain, is the outward manifestation of coronary heart disease.So coronary heart disease is the disease of deficiency in origin and excess in superficiality.Treatment should be basic with dispelling cold and activating YANG, resolving depression of regulating the flow of vital energy, a surname's numbness of invigorating blood circulation, benefiting qi and nourishing yin, nourishing blood and promoting blood circulation, therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and Patients in Hospital with Coronary Heart Disease 127 example for 2009 altogether between year December of January ~ 2012, be divided into treatment group 67 example and matched group 60 example at random, treatment group man 43 example, female 24 example, 38 ~ 61 years old age, 49.6 years old mean age, the course of disease 4 ~ 13 years; Matched group man 37 example, female 23 example, 39 ~ 64 years old age, 49.4 years old mean age, the course of disease 3 ~ 18 years.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) classical angina is had to show effect and myocardial infarction, and without severe aortic stenosis, incompetence, aortitis, also without coronary thrombosis or myocardiac evidence; 2) patient of male 40 years old, women more than 45 years old, during rest, electrocardiogram has obvious myocardial ischemia to show, or ECG exercise test is positive, can look into without other reason (various heart disease, autonomic nervous dysfunction, significantly anemia, obstructive emphysema, take Folium Digitalis Purpureae, electrolyte disturbance), and have two persons in following three: hypertension, hypercholesterolemia, diabetes.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.12 weeks courses for the treatment of.
The oral Ismo 20 sheet of matched group (North China pharmacy), takes according to its description.12 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: symptom and sign significantly takes a turn for the better, angina pectoris frequency obviously reduces, and is less than treatment front 80% or substantially disappears; Angina pectoris classification improves 2 grades, and rest ECG is normal;
Effective: symptom and sign is alleviated, angina pectoris number of times reduces, and be less than treatment front 50% ~ 80%, angina pectoris classification improves 1 grade, ECG ST rise >=0.05mv, but does not reach normal level;
Invalid: original symptom and sign is without being clearly better, and angina pectoris attacks number of times, degree, the persistent period is unchanged or increase the weight of, and angina pectoris classification is unchanged.Electrocardiogram is basic identical with front or increase the weight of: ST section reduces > 0.05mv before comparatively treating.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Group n Effective Effectively Invalid Total effective rate (%) Serious adverse reaction example
Treatment group 67 35 22 10 85.07% 0
Matched group 60 21 19 20 66.67% 0
Visible, the medicine that the present invention obtains can safe and effective treatment coronary heart disease, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Asari 3 grams, Bulbus Allii Macrostemonis 8 grams, Rhizoma Polygonati Odorati 10 grams, Poria cum Radix Pini 10 grams, Lignum Dalbergiae Odoriferae 12 grams, Radix Aristolochiae 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of coronary heart disease.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Herba Asari 3 grams, Bulbus Allii Macrostemonis 8 grams, Rhizoma Polygonati Odorati 10 grams, Poria cum Radix Pini 10 grams, Lignum Dalbergiae Odoriferae 12 grams, Radix Aristolochiae 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of coronary heart disease.Oral, daily once.
Specific embodiment 3
Take: Herba Asari 3 grams, Bulbus Allii Macrostemonis 8 grams, Rhizoma Polygonati Odorati 10 grams, Poria cum Radix Pini 10 grams, Lignum Dalbergiae Odoriferae 12 grams, Radix Aristolochiae 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of coronary heart disease.Oral, every bu is taken for twice sooner or later.

Claims (4)

1. be used for the treatment of a Chinese medicine for coronary heart disease, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Asari 3 parts, Bulbus Allii Macrostemonis 8 parts, Rhizoma Polygonati Odorati 10 parts, Poria cum Radix Pini 10 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Aristolochiae 6 parts.
2. a kind of Chinese medicine being used for the treatment of coronary heart disease as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Asari 3 parts, Bulbus Allii Macrostemonis 8 parts, Rhizoma Polygonati Odorati 10 parts, Poria cum Radix Pini 10 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Aristolochiae 6 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of coronary heart disease as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Asari 3 parts, Bulbus Allii Macrostemonis 8 parts, Rhizoma Polygonati Odorati 10 parts, Poria cum Radix Pini 10 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Aristolochiae 6 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of coronary heart disease as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Asari 3 parts, Bulbus Allii Macrostemonis 8 parts, Rhizoma Polygonati Odorati 10 parts, Poria cum Radix Pini 10 parts, Lignum Dalbergiae Odoriferae 12 parts, Radix Aristolochiae 6 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
CN201510055631.8A 2015-02-01 2015-02-01 Traditional Chinese medicine for treating coronary heart disease Pending CN104623279A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596672A (en) * 2016-01-25 2016-05-25 陈锦清 Medicine for treating cardiomyopathy

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CN1853711A (en) * 2005-04-18 2006-11-01 广州博济医药生物技术有限公司 Xinmaikangzhong Chinese medicinal composition and preparation thereof

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* Cited by examiner, † Cited by third party
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CN105596672A (en) * 2016-01-25 2016-05-25 陈锦清 Medicine for treating cardiomyopathy

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