CN1294961C - Oral liquid for curing myocardial ischemia and process for preparing the same - Google Patents

Oral liquid for curing myocardial ischemia and process for preparing the same Download PDF

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Publication number
CN1294961C
CN1294961C CN 200510017818 CN200510017818A CN1294961C CN 1294961 C CN1294961 C CN 1294961C CN 200510017818 CN200510017818 CN 200510017818 CN 200510017818 A CN200510017818 A CN 200510017818A CN 1294961 C CN1294961 C CN 1294961C
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water
myocardial ischemia
medicinal liquid
liquid
oral liquid
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CN 200510017818
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CN1733198A (en
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史进宝
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Abstract

The invention relates to oral liquid for curing myocardial ischemia and a preparation process thereof, which can obtain the purpose of curing the myocardial ischemia effectively. The oral liquid has the technical scheme that the oral liquid is prepared from gualou, macrostem onion, ginger tuber pinellia, dried orange peel, radix salviae miltiorrhizae, macrostem, magnolia bark, cassia twigs and water. The preparation process comprises the following steps: the water for immersing medicine powder is added in proportion by weight according to need, and medicinal powder is immersed by the water and boiled, the water and the medicinal powder are boiled for 20 to 30 minutes by small fire; after the medicinal powder is filtered, water is added to immerse the medicinal powder; after being boiled, the water and the medicinal powder are boiled for 20 to 25 minutes by the small fire; the medicinal powder is filtered; the medicinal liquid is mixed again and concentrated to the medicinal liquid which is four times as heavy as original biological medicine. The medicinal liquid of the present invention has the advantages of convenience in taking the medicinal liquid, good effect, low cost and simple preparation; the oral liquid can be directly decocted or filled in bags for taking the medicinal liquid. The success of research brings good news for patients with myocardial ischemia, and makes creation contribution to a treasure house of traditional Chinese medicine.

Description

A kind of oral liquid for the treatment of myocardial ischemia and preparation method thereof
One, technical field
The present invention relates to a kind of oral liquid (decoction) for the treatment of myocardial ischemia of usefulness clinically and preparation method thereof.
Two, background technology
Myocardial ischemia is a kind of common frdquently encountered disease, cause has multiple situation, healthy and life security to the people has constituted serious threat, for example angina pectoris is on the basis of coronary atherosclerotic heart disease (coronary heart disease), coronary artery causes blood supply insufficiency because of spasm, rapid, temporary transient ischemia of cardiac muscle and the caused acute clinical syndrome of anoxia, if untimely treatment, but threat to life; Myocardial infarction and for example, be on the basis of coronary heart disease, owing to coronary blood causes the myocardial ischemia necrosis for minimizing or interruption, if treatment is ineffective, patient's be in peril of one's life at any time (death), myocardial ischemia, the category of the genus traditional Chinese medical science thoracic obstruction, the traditional Chinese medical science claims it is by yang-energy is depressed in the heart, essential resistance of turbid phlegm or depressed blood stasis, due to the YIN pathogen superinverse, its cardinal symptom is the fullness in the chest chest pain, it is unfavorable to lose heart, and pain is drawn the heart back of the body.The treatment myocardial ischemia adopts blood vessel dilating more at present, the medicine of activating YANG and eliminating stagnation, eliminate the phlegm the chest stuffiness relieving and blood circulation promoting and blood stasis dispelling, for example DIAOXINXUE KANG, SUXIAO JIUXIN WAN etc., during acute onset, send treatment to hospital, but for various reasons, these medicines and means are also unsatisfactory at present, people do not satisfy these medicines and emergency treatment, and therefore, novel drugs is weeded out the old and bring forth the new imperative.
Three, summary of the invention
Actual needs at above-mentioned situation and treatment myocardial ischemia, the present invention just provides a kind of oral liquid (decoction) for the treatment of myocardial ischemia and preparation method thereof, can effectively solve the treatment problem of myocardial ischemia, the technical scheme of its solution is, the present invention is by Fructus Trichosanthis, Bulbus Allii Macrostemonis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Pericarpium Citri Reticulatae, Radix Salviae Miltiorrhizae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Ramulus Cinnamomi and water are made, its preparation method is, add water logging by the requirement of component amount and do not have powder, after immersion is boiled, 20-30 at a simmer minute, after leaching medicinal liquid, add water to submerge powder again, after boiling, slow fire was fried in shallow oil 20-25 minute again, leach medicinal liquid, merge the secondary medicinal liquid, the medicinal liquid that is concentrated into 4 times of amounts of primary medicine bulking value gets final product that (said bulking value is meant medicine weight meter, the liquid stereometer, and the calculating of volume is volume amount with the weight number, as the 100g medicine, changes bulking value into and is 100ml, this medicinal liquid taking convenience, effective, expense is low, and preparation is simple, directly decoction or pack are taken and all can, it is succeeded in developing, and the patient brings glad tidings for myocardial ischemia, for the Chinese medicine and pharmacy treasure-house has increased new wonderful work and creative contribution.
Four, the specific embodiment
Provide by technical scheme, oral liquid of the present invention is the medicine by by weight percentage: Fructus Trichosanthis 20%, Bulbus Allii Macrostemonis 20%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10%, Pericarpium Citri Reticulatae 8%, Radix Salviae Miltiorrhizae 20%, Fructus Aurantii Immaturus 8%, Cortex Magnoliae Officinalis 10%, Ramulus Cinnamomi 4% and water are made, its preparation method is the medicine with weight percent meter: Fructus Trichosanthis 20%, Bulbus Allii Macrostemonis 20%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10%, Pericarpium Citri Reticulatae 8%, Radix Salviae Miltiorrhizae 20%, Fructus Aurantii Immaturus 8%, Cortex Magnoliae Officinalis 10%, Ramulus Cinnamomi 4% is added water to submerge powder, soaked 1 hour, after boiling, 20-30 at a simmer minute, leach medicinal liquid, add water to submerge powder again, after boiling, slow fire was fried in shallow oil 20-25 minute again, leach medicinal liquid, merge medicinal liquid twice, be concentrated into the medicinal liquid of 4 times of amounts of primary medicine bulking value, divide in the pack to get final product.Medicine of the present invention also can directly add by the requirement of component amount and is decocted in water for oral dose, and every dose of morning and evening fries in shallow oil once and take.For example one day is example with a dosage, by the requirement of component amount, medicine of the present invention is by Fructus Trichosanthis 30g, Bulbus Allii Macrostemonis 30g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g, Pericarpium Citri Reticulatae 12g, Radix Salviae Miltiorrhizae 30g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 15g, Ramulus Cinnamomi 6g and water are made, its preparation method is with Fructus Trichosanthis 30g, Bulbus Allii Macrostemonis 30g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g, Pericarpium Citri Reticulatae 12g, Radix Salviae Miltiorrhizae 30g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 15g, Ramulus Cinnamomi 6g is added water to submerge powder and was soaked 1 hour, after being fried boiling 30 minutes at a simmer again, after medicinal liquid is poured out in filtration, add water to submerge powder again, after being fried boiling 20 minutes at a simmer again, medicinal liquid is poured out in filtration, merge medicinal liquid twice, be concentrated into 600ml, in 2 bags of the packing, be the convenient water that in medicine, adds, the water that generally can add medicine gross weight 6-8 amount adds 8 times of water gagings for the first time, adds 6 times of water gagings the 2nd time, in order to reduce injection volume, also can suitably the medicine chopping be decocted again every bag of 300ml (also can be used as decoction, sooner or later respectively fry in shallow oil once and take).
Said Fructus Trichosanthis claims Fructus Trichosanthis again, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is to be formed through the Sucus Zingberis immersion treatment by the Rhizoma Pinelliae, specifically: float the good Rhizoma Pinelliae and Rhizoma Zingiberis Recens, vitriol after will salting down with moving in the pot, clear water is well-done to be dried, also have with clear water and float well-done the drying in back, mix with fresh ginger juice and evenly to dry promptly, above-mentioned each medicine all is the medicines that cook by the Chinese medicine requirement, has promptly met the medicine of herbal pharmaceutical requirement.The present invention also can be made into powder, uses warm boiled water, or incapsulates and take.Said medicine, wherein: Fructus Trichosanthis is washed away the greasy expectorant of dirt; Bulbus Allii Macrostemonis warming middle-JIAO eliminating stagnation gas; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling; Pericarpium Citri Reticulatae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) expectorant stomach function regulating; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis remove painful abdominal mass and loose full; Ramulus Cinnamomi activates yang and flat contrary gas, and confirms that through modern pharmacological research Fructus Trichosanthis, Bulbus Allii Macrostemonis, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi all have the coronary artery dilator blood vessel, the effect of blood flow increasing, thereby, originally can remove antetheca, rear wall, the illness of sidewall, inferior myocardial ischemia.And also fully proved unique curative effect of medicine of the present invention in the clinical practice.And the user all has no adverse reaction, and stable curative effect is reliable.Concrete clinical data is as follows:
One, diagnostic criteria
The full chest pain of all brains, it is unfavorable to lose heart, and pain is drawn the heart back of the body, shortness of breath and palpitation, symptoms such as lassitude are diagnosable to be myocardial ischemia.
Two, select the standard of case
Meet above-mentioned diagnostic criteria patient with sympotoms all as selecting the case standard, carry out clinical application.
Three, therapeutic scheme
The patient services once sooner or later, and each 300ml (promptly is packed) serve on 5-15 days observe the curative effect, or directly press embodiment one dosage, fries in shallow oil into decoction and directly takes, and the morning and evening, respectively once one day potion serve on the 5-15 agent, and establishes contrast groups and compare.Preferably treatment was observed 30 days continuously.
Four, efficacy assessment standard
Recovery from illness: the symptom complete obiteration, and in 3 years the recidivist is not arranged.The check of having an electro-cardiogram is normal.
Effectively: symptom is improved in various degree, in 1 year the recidivist is not arranged.
Invalid: symptom does not have obvious improvement, even the trend that increases the weight of is arranged.Electrocardioscopy has unusually.
Five, statistical procedures
According to selecting the case standard, through outpatient service with select case 160 people, wherein male 98 people in hospital altogether, woman 62 people, age is at 35-75 between year, experimental group 108 people, matched group 52 people, press such scheme, experimental group medicine of the present invention, matched group DIAOXINXUE KANG, SUXIAO JIUXIN WAN, 15 days is an observation period, the observation of taking medicine in continuous 30 days, the result is as follows:
The example number Recovery from illness Effectively Invalid Total effective rate
Experimental group 108 91 14 3 97.2%
Matched group 52 24 21 5 86.5%
Find out that by The above results cure rate of the present invention is 85%, effective 13.3%, invalid 2.7%, total effective rate is 97.2%, obviously is better than matched group, the patient reacts medicine of the present invention and is popular, for example Ruzhou, Henan patient peace * *, the man, 62 years old, suffer from feeling of oppression and pain in the chest in May, 99, shortness of breath and palpitation, the thorough heart back of the body of pain in the time of very, and be everlasting be roused from sleep after, once it is surplus to arrive city's hospital therapy moon, takes DIAOXINXUE KANG and SUXIAO JIUXIN WAN, though symptom has alleviation, but it is and unsatisfactory, patient's lassitude feels down in spirits, even funeral affairs make dispositions, the inventor for some reason meets, after diagnosing, patient's body of the tongue is dim, yellow and greasy fur, Electrocardioscopy is diagnosed as inferior myocardial ischemia, the inventor persuades medicine of the present invention, behind the potion clothes, feel good, symptom is obviously improved after three doses, after serveing on 5 days, chest pain is slight, and after 10 days, chest pain disappears, spirit is good, after 15 days, symptom disappears entirely, and electrocardiogram is normal fully, after again this prescription is ground powdered, every day three times, each soupspoon is obeyed three dosage, to consolidate curative effect, so far not recurrence, and healthy, normally work and live.
Six, conclusion
From the above, medicine of the present invention is a kind of effective new drug of treatment myocardial ischemia, and drug safety has no adverse reaction, and curative effect is better than existing medicine up to more than 97%, the practical significance of clinical practice is arranged, development prospect light.It is succeeded in developing is creative contribution to Chinese medicine and pharmacy, and the economy and society benefit is huge, must bring benefit to the mankind.

Claims (4)

1, a kind of oral liquid for the treatment of myocardial ischemia is characterized in that being, by medicine by weight percentage: Fructus Trichosanthis 20%, Bulbus Allii Macrostemonis 20%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10%, Pericarpium Citri Reticulatae 8%, Radix Salviae Miltiorrhizae 20%, Fructus Aurantii Immaturus 8%, Cortex Magnoliae Officinalis 10%, Ramulus Cinnamomi 4% and water are made.
2, a kind of oral liquid for the treatment of myocardial ischemia according to claim 1 is characterized in that, said this oral liquid is to be made by Fructus Trichosanthis 30g, Bulbus Allii Macrostemonis 30g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g, Pericarpium Citri Reticulatae 12g, Radix Salviae Miltiorrhizae 30g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 15g, Ramulus Cinnamomi 6g and water.
3, a kind of preparation method for the treatment of the oral liquid of myocardial ischemia according to claim 1, it is characterized in that being, medicine with weight percent meter: Fructus Trichosanthis 20%, Bulbus Allii Macrostemonis 20%, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10%, Pericarpium Citri Reticulatae 8%, Radix Salviae Miltiorrhizae 20%, Fructus Aurantii Immaturus 8%, Cortex Magnoliae Officinalis 10%, Ramulus Cinnamomi 4% are added water to submerge powder, soaked 1 hour, after boiling, 20-30 at a simmer minute, leach medicinal liquid, add water to submerge powder again, after boiling, slow fire was fried in shallow oil 20-25 minute again, leach medicinal liquid, merge medicinal liquid twice, be concentrated into the medicinal liquid of 4 times of amounts of primary medicine bulking value, divide in the pack.
4, a kind of preparation method for the treatment of the oral liquid of myocardial ischemia according to claim 3, it is characterized in that being, Fructus Trichosanthis 30g, Bulbus Allii Macrostemonis 30g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15g, Pericarpium Citri Reticulatae 12g, Radix Salviae Miltiorrhizae 30g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 15g, Ramulus Cinnamomi 6g are added water to submerge powder to be soaked 1 hour, after being fried boiling 30 minutes at a simmer again, filter pour out medicinal liquid after, add water to submerge powder again, after being fried boiling 20 minutes at a simmer again, medicinal liquid is poured out in filtration, merges twice medicinal liquid and is concentrated into 600ml, in 2 bags of the packing.
CN 200510017818 2005-07-25 2005-07-25 Oral liquid for curing myocardial ischemia and process for preparing the same Expired - Fee Related CN1294961C (en)

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Application Number Priority Date Filing Date Title
CN 200510017818 CN1294961C (en) 2005-07-25 2005-07-25 Oral liquid for curing myocardial ischemia and process for preparing the same

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CN1294961C true CN1294961C (en) 2007-01-17

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105079693A (en) * 2015-08-31 2015-11-25 黄宇松 Traditional Chinese medicine combination for treating chest stuffiness pain
CN109125693A (en) * 2018-09-28 2019-01-04 周妍 For improving the Chinese herbal medicine of myocardial blood supply, drug paste and the preparation method of drug paste

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