CN104288392A - Traditional Chinese medicine for treating atherosclerosis - Google Patents
Traditional Chinese medicine for treating atherosclerosis Download PDFInfo
- Publication number
- CN104288392A CN104288392A CN201410622326.8A CN201410622326A CN104288392A CN 104288392 A CN104288392 A CN 104288392A CN 201410622326 A CN201410622326 A CN 201410622326A CN 104288392 A CN104288392 A CN 104288392A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- treatment
- water gagings
- decoct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 16
- 201000001320 Atherosclerosis Diseases 0.000 title abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000000706 filtrate Substances 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 238000004806 packaging method and process Methods 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 3
- 241000427159 Achyranthes Species 0.000 abstract 1
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 18
- 210000004369 blood Anatomy 0.000 description 18
- 206010003210 Arteriosclerosis Diseases 0.000 description 7
- 208000011775 arteriosclerosis disease Diseases 0.000 description 7
- 208000002173 dizziness Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 5
- 235000019634 flavors Nutrition 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 206010002383 Angina Pectoris Diseases 0.000 description 4
- 206010008479 Chest Pain Diseases 0.000 description 4
- 210000000038 chest Anatomy 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010023126 Jaundice Diseases 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 206010003119 arrhythmia Diseases 0.000 description 3
- 230000006793 arrhythmia Effects 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 230000004064 dysfunction Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 208000031225 myocardial ischemia Diseases 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 235000003069 Artemisia scoparia Nutrition 0.000 description 2
- 241001249148 Artemisia scoparia Species 0.000 description 2
- 206010030302 Oliguria Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 241001518821 Typha orientalis Species 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 210000000709 aorta Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 230000003419 expectorant effect Effects 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000009278 visceral effect Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 240000000031 Achyranthes bidentata Species 0.000 description 1
- 244000001632 Acorus gramineus Species 0.000 description 1
- 241000544682 Acorus tatarinowii Species 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241000049624 Alisma plantago-aquatica subsp. orientale Species 0.000 description 1
- 206010059245 Angiopathy Diseases 0.000 description 1
- 235000008658 Artemisia capillaris Nutrition 0.000 description 1
- 241000092668 Artemisia capillaris Species 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 206010017577 Gait disturbance Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010024642 Listless Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010061876 Obstruction Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 102000001938 Plasminogen Activators Human genes 0.000 description 1
- 108010001014 Plasminogen Activators Proteins 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010042170 Strangury Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 235000004224 Typha angustifolia Nutrition 0.000 description 1
- 240000001398 Typha domingensis Species 0.000 description 1
- 241000233945 Typhaceae Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000002302 brachial artery Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000000039 congener Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000003017 ductus arteriosus Anatomy 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 238000002592 echocardiography Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 201000005577 familial hyperlipidemia Diseases 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000002559 palpation Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000009527 percussion Methods 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 229940127126 plasminogen activator Drugs 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 210000002321 radial artery Anatomy 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001994 temporal artery Anatomy 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 231100000216 vascular lesion Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine for treating atherosclerosis. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 8 parts of rhizoma acori graminei, 7 parts of rhizoma alismatis, 13 parts of oriental wormwood, 8 parts of pollen typhae and 7 parts of achyranthes. Clinical experiments prove that the traditional Chinese medicine can safely and effectively treat atherosclerosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of arteriosclerotic Chinese medicine.
Background technology
Arteriosclerosis is a kind of non-inflammation pathological changes of tremulous pulse, ductus arteriosus wall can be made to thicken, hardening, follows the string, luminal stenosis.Clinical manifestation depends mainly on the degree of ischemia of vascular lesion and afflicted organ, for early stage arteriosclerotic, Most patients nearly all without any clinical symptoms, development of hiding under being all in concealment state.For the arteriosclerotic in mid-term, the clinical symptoms such as Most patients all more or less listless and aching, the limping of had palpitation, chest pain, uncomfortable in chest, headache, dizziness, the cool fiber crops of extremity, extremity, vision reduction, hypomnesis, insomnia and dreamful sleep, different patients has different symptoms.Generally show as mental and flag, palpation body surface artery is as elongated, tortuous and hardening in Temporal Artery, radial artery, brachial artery etc. can find to broaden.
Arteriosclerosis be with age and occur angiopathy, its rule normally adolescence occur, increase the weight of period to person in middle and old age, fall ill.Male is many compared with women, and primary disease increases gradually in China in recent years, becomes one of old people's main cause of death.
Hypertension, hyperlipemia, smoking is the most important thing is in the arteriosclerotic cause of disease, its pathogeny is completely not clear and definite so far, current western medicine can use thrombus medicine, anticoagulation, as urokinase, recombinant tissue-type's plasminogen activator, heparin etc., but its therapeutic effect is all undesirable and side effect is larger.
Primary disease belongs to the category such as the traditional Chinese medical science " blood stasis ", " expectorant is turbid ", " stagnation of QI ", " cold coagulation " according to its clinical manifestation.
Medical material present Research involved in the present invention is as follows:
Rhizoma Acori Graminei [source] this product is the dry rhizome of acorus gramineus araceae plant (Acorus tatarinowii Schott).Autumn, season in winter two excavate, and removing fibrous root and silt, dry.[nature and flavor] are pungent, bitter, temperature.[return through] GUIXIN, stomach warp.[function cures mainly] removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.[usage and dosage] 3 ~ 9g.
Rhizoma Alismatis [source] this product is the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis (Alisma orientalis Juzep.).Excavate when winter, stem and leaf started withered, cleaning, drying, removing fibrous root and rough bark.[nature and flavor] are sweet, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.[usage and dosage] 6 ~ 9g.
Herba Artemisiae Scopariae [source] this product is the dry aerial parts of feverfew Artemisia scoparia Waldst. et Kit. (Artemisia scoparia Waldst. et Kit.) or Herba Artemisiae Scopariae (Artemisia capillaris Thunb.).Gather during the high 6 ~ 10cm of seedling in spring or autumn, alabastrum grew up to time tap, removing impurity and old stem, dry.[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns spleen, stomach, liver, gallbladder meridian.[function cures mainly] clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.[usage and dosage] 6 ~ 15g.
Pollen Typhae [source] this product is the dry pollen of the turbid Herba Typhae of Typhaceae vegetation water (Typha angustifolia L.), typha orientalis (Typha orientalis Presl) or congener.Gather summer the yellow staminate inflorescence on Spica Typhae top, dry rear rolloff, sieve gets pollen.After clip male flower, dry, become the pollen with male flower, be POLLEN TYPHAE CUM STAMEN.[nature and flavor] are sweet, flat.[return through] returns liver, pericardium channel.[function cures mainly] stops blooding, and blood stasis dispelling is treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.[usage and dosage] 5 ~ 9g.
Radix Achyranthis Bidentatae [source] this product is the dry root of amaranthaceous plant Radix Achyranthis Bidentatae (Achyranthes bidentata Blume.).Excavate when winter, stem and leaf was withered, removing fibrous root and silt, be bundled into wisp, shine to shriveling, trimmed on top, dry.[nature and flavor] are bitter, sour, flat.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.[usage and dosage] 4.5 ~ 9g.
Summary of the invention
The present invention aims to provide one and is used for the treatment of arteriosclerotic Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the arteriosclerotic object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One is used for the treatment of arteriosclerotic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts.
Inventor thinks that arteriosclerosis is with visceral dysfunction, then the qi-blood-body fluid interruption of service.If taste are impaired, make the dysfunction of the spleen, defeatedization is not normal, then essence of water and grain becomes turbid fat, enters blood and blood fat is raised; Turbid fat is cumulative, must not Qinghua and the expectorant become in blood is turbid.The blood flow of people is among blood vessels, and visceral dysfunction then blood fortune is not smooth, and easily the raw stasis of blood is stagnant.Phlegm and blood stasis and cause atherosclerosis, causes all diseases such as apoplexy, the thoracic obstruction, angina pectoris, dementia.Treatment should be basic with blood circulation promoting and blood stasis dispelling, blood fat reducing of eliminating the phlegm, righting tonify deficiency method (invigorating the spleen and benefiting QI, liver and kidney tonifying), therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and arteriosclerotic 75 example of being in hospital altogether between in August, 2011 ~ in November, 2013, be divided into treatment group 40 example and matched group 35 example at random, treatment group man 22 example, female 18 example, 33 ~ 68 years old age, 48.5 years old mean age, the course of disease 1 ~ 3 year; Matched group man 21 example, female 14 example, 30 ~ 68 years old age, 47.9 years old mean age, the course of disease 1 ~ 3 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) have palpitation, breathe hard, sense of discomfort is felt oppressed in pareordia; 2) percussion: presternum aorta posterior dullness area is broadening, second sound of aortic area is hyperfunction; 3) color echocardiography shows: aortosclerosis, ascending aorta are slightly broadening.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.8 weeks courses for the treatment of.
The oral Atorvaststin of matched group (Beijing Jia Lin pharmaceutical Co. Ltd), takes according to its description.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape are clearly better, angina pectoris, arrhythmia, myocardial ischemia occur obviously to reduce, and blood fat, blood pressure, Hemorheology inspection are normal;
Effective: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape have certain improvement, angina pectoris, arrhythmia, myocardial ischemia occur to reduce to some extent, and blood fat, blood pressure, Hemorheology inspection transfer attention to by danger;
Invalid: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape without improvement, angina pectoris, arrhythmia, myocardial ischemia often occur, and do not change even aggravation before blood fat, blood pressure, Hemorheology inspection and treatment.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Group | n | Effective | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
Treatment group | 40 | 17 | 20 | 3 | 92% | 0 |
Matched group | 35 | 9 | 18 | 8 | 70% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment arteriosclerosis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, daily once.
Specific embodiment 3
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. be used for the treatment of an arteriosclerotic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts.
2. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410622326.8A CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410622326.8A CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104288392A true CN104288392A (en) | 2015-01-21 |
Family
ID=52308503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410622326.8A Pending CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104288392A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104547780A (en) * | 2015-02-09 | 2015-04-29 | 王士国 | Drug for treating chronic arteriosclerosis caused by hyperlipidemia and preparation thereof |
CN105250979A (en) * | 2015-11-20 | 2016-01-20 | 王秀娟 | Traditional Chinese medicine pills for treating atherosclerosis and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1669488A (en) * | 2005-03-29 | 2005-09-21 | 张雪晴 | Formula of health beverage |
CN1682936A (en) * | 2005-02-25 | 2005-10-19 | 石家庄四药有限公司 | Medicinal composition for treating hyperlipemia and its preparing method |
CN102772491A (en) * | 2012-08-17 | 2012-11-14 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating lower extremity atherosclerotic disease and application of composition |
CN103768297A (en) * | 2014-01-15 | 2014-05-07 | 解程 | Traditional Chinese medicine for treating hyperlipoidemia |
-
2014
- 2014-11-07 CN CN201410622326.8A patent/CN104288392A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1682936A (en) * | 2005-02-25 | 2005-10-19 | 石家庄四药有限公司 | Medicinal composition for treating hyperlipemia and its preparing method |
CN1669488A (en) * | 2005-03-29 | 2005-09-21 | 张雪晴 | Formula of health beverage |
CN102772491A (en) * | 2012-08-17 | 2012-11-14 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating lower extremity atherosclerotic disease and application of composition |
CN103768297A (en) * | 2014-01-15 | 2014-05-07 | 解程 | Traditional Chinese medicine for treating hyperlipoidemia |
Non-Patent Citations (1)
Title |
---|
周立群等: "《国际中医药现代研究96首届国际中医药杰出成果交流展示会论文集-中英文对照》", 31 May 1996, 中国中医药出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104547780A (en) * | 2015-02-09 | 2015-04-29 | 王士国 | Drug for treating chronic arteriosclerosis caused by hyperlipidemia and preparation thereof |
CN105250979A (en) * | 2015-11-20 | 2016-01-20 | 王秀娟 | Traditional Chinese medicine pills for treating atherosclerosis and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102178800B (en) | Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
CN102178903B (en) | Method for preparing traditional Chinese medicine for treating acute pancreatitis caused by overeating greasy food | |
CN1977899B (en) | Medicine for treating rheumatoid arthritis | |
CN104083438A (en) | Balsam pear-containing traditional Chinese medicinal preparation for alleviating hypertension, and preparation method thereof | |
CN104288392A (en) | Traditional Chinese medicine for treating atherosclerosis | |
CN105999049A (en) | Traditional Chinese medicine composition for treating chronic renal failure and complications thereof | |
CN102631630B (en) | Method for preparing traditional Chinese medicine (TCM) for treating intestine and stomach dyspepsia type colitis | |
CN104758900A (en) | Traditional Chinese medicine for treating acute pancreatitis | |
CN104800504A (en) | Traditional Chinese medicine preparation for treating nephritis and preparation method | |
CN104306929A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method of traditional Chinese medicine formula | |
CN104225399A (en) | Traditional Chinese medicine for treating pulmonary tuberculosis | |
CN100381161C (en) | Medicine ointment for treating swelling and pain in waist and knees | |
CN103920102A (en) | Traditional Chinese medicine for treating primary hypotension | |
CN102258599A (en) | Chinese medicine for treating cardiovascular diseases | |
CN102008697B (en) | Medicinal liquor for curing nephropathy and preparation method thereof | |
CN102145150B (en) | Medicine for treatment of uninary calculi | |
CN104800464A (en) | Traditional Chinese medicine for treating urticaria | |
CN104274642A (en) | Traditional Chinese medicine for treating gout | |
CN103961658A (en) | Capsule preparation for lowering lipid and protecting liver | |
CN104189615B (en) | Traditional Chinese medicine preparation for treating metrorrhagia and metrostaxis, and preparation method of traditional Chinese medicine preparation | |
CN102793826B (en) | Traditional Chinese medicine for treating hypertension early-stage kidney damage and preparation method thereof | |
CN102579688A (en) | Blood pressure reducing chrysanthemum and dogbane leaf traditional Chinese medicine preparation | |
CN109674908A (en) | It is a kind of for treating the Chinese medicine of artery sclerosis | |
CN104491556B (en) | A kind of Chinese medicine composition for the treatment of caused by hepatic stagnation qi stagnation prostatic hyperplasia | |
CN103405597B (en) | One treats arteriosclerotic medicine and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150121 |
|
WD01 | Invention patent application deemed withdrawn after publication |