CN104288392A - Traditional Chinese medicine for treating atherosclerosis - Google Patents
Traditional Chinese medicine for treating atherosclerosis Download PDFInfo
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- CN104288392A CN104288392A CN201410622326.8A CN201410622326A CN104288392A CN 104288392 A CN104288392 A CN 104288392A CN 201410622326 A CN201410622326 A CN 201410622326A CN 104288392 A CN104288392 A CN 104288392A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention relates to a traditional Chinese medicine for treating atherosclerosis. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 8 parts of rhizoma acori graminei, 7 parts of rhizoma alismatis, 13 parts of oriental wormwood, 8 parts of pollen typhae and 7 parts of achyranthes. Clinical experiments prove that the traditional Chinese medicine can safely and effectively treat atherosclerosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of arteriosclerotic Chinese medicine.
Background technology
Arteriosclerosis is a kind of non-inflammation pathological changes of tremulous pulse, ductus arteriosus wall can be made to thicken, hardening, follows the string, luminal stenosis.Clinical manifestation depends mainly on the degree of ischemia of vascular lesion and afflicted organ, for early stage arteriosclerotic, Most patients nearly all without any clinical symptoms, development of hiding under being all in concealment state.For the arteriosclerotic in mid-term, the clinical symptoms such as Most patients all more or less listless and aching, the limping of had palpitation, chest pain, uncomfortable in chest, headache, dizziness, the cool fiber crops of extremity, extremity, vision reduction, hypomnesis, insomnia and dreamful sleep, different patients has different symptoms.Generally show as mental and flag, palpation body surface artery is as elongated, tortuous and hardening in Temporal Artery, radial artery, brachial artery etc. can find to broaden.
Arteriosclerosis be with age and occur angiopathy, its rule normally adolescence occur, increase the weight of period to person in middle and old age, fall ill.Male is many compared with women, and primary disease increases gradually in China in recent years, becomes one of old people's main cause of death.
Hypertension, hyperlipemia, smoking is the most important thing is in the arteriosclerotic cause of disease, its pathogeny is completely not clear and definite so far, current western medicine can use thrombus medicine, anticoagulation, as urokinase, recombinant tissue-type's plasminogen activator, heparin etc., but its therapeutic effect is all undesirable and side effect is larger.
Primary disease belongs to the category such as the traditional Chinese medical science " blood stasis ", " expectorant is turbid ", " stagnation of QI ", " cold coagulation " according to its clinical manifestation.
Medical material present Research involved in the present invention is as follows:
Rhizoma Acori Graminei [source] this product is the dry rhizome of acorus gramineus araceae plant (Acorus tatarinowii Schott).Autumn, season in winter two excavate, and removing fibrous root and silt, dry.[nature and flavor] are pungent, bitter, temperature.[return through] GUIXIN, stomach warp.[function cures mainly] removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.[usage and dosage] 3 ~ 9g.
Rhizoma Alismatis [source] this product is the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis (Alisma orientalis Juzep.).Excavate when winter, stem and leaf started withered, cleaning, drying, removing fibrous root and rough bark.[nature and flavor] are sweet, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.[usage and dosage] 6 ~ 9g.
Herba Artemisiae Scopariae [source] this product is the dry aerial parts of feverfew Artemisia scoparia Waldst. et Kit. (Artemisia scoparia Waldst. et Kit.) or Herba Artemisiae Scopariae (Artemisia capillaris Thunb.).Gather during the high 6 ~ 10cm of seedling in spring or autumn, alabastrum grew up to time tap, removing impurity and old stem, dry.[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns spleen, stomach, liver, gallbladder meridian.[function cures mainly] clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.[usage and dosage] 6 ~ 15g.
Pollen Typhae [source] this product is the dry pollen of the turbid Herba Typhae of Typhaceae vegetation water (Typha angustifolia L.), typha orientalis (Typha orientalis Presl) or congener.Gather summer the yellow staminate inflorescence on Spica Typhae top, dry rear rolloff, sieve gets pollen.After clip male flower, dry, become the pollen with male flower, be POLLEN TYPHAE CUM STAMEN.[nature and flavor] are sweet, flat.[return through] returns liver, pericardium channel.[function cures mainly] stops blooding, and blood stasis dispelling is treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.[usage and dosage] 5 ~ 9g.
Radix Achyranthis Bidentatae [source] this product is the dry root of amaranthaceous plant Radix Achyranthis Bidentatae (Achyranthes bidentata Blume.).Excavate when winter, stem and leaf was withered, removing fibrous root and silt, be bundled into wisp, shine to shriveling, trimmed on top, dry.[nature and flavor] are bitter, sour, flat.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.[usage and dosage] 4.5 ~ 9g.
Summary of the invention
The present invention aims to provide one and is used for the treatment of arteriosclerotic Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the arteriosclerotic object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One is used for the treatment of arteriosclerotic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts.
Inventor thinks that arteriosclerosis is with visceral dysfunction, then the qi-blood-body fluid interruption of service.If taste are impaired, make the dysfunction of the spleen, defeatedization is not normal, then essence of water and grain becomes turbid fat, enters blood and blood fat is raised; Turbid fat is cumulative, must not Qinghua and the expectorant become in blood is turbid.The blood flow of people is among blood vessels, and visceral dysfunction then blood fortune is not smooth, and easily the raw stasis of blood is stagnant.Phlegm and blood stasis and cause atherosclerosis, causes all diseases such as apoplexy, the thoracic obstruction, angina pectoris, dementia.Treatment should be basic with blood circulation promoting and blood stasis dispelling, blood fat reducing of eliminating the phlegm, righting tonify deficiency method (invigorating the spleen and benefiting QI, liver and kidney tonifying), therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and arteriosclerotic 75 example of being in hospital altogether between in August, 2011 ~ in November, 2013, be divided into treatment group 40 example and matched group 35 example at random, treatment group man 22 example, female 18 example, 33 ~ 68 years old age, 48.5 years old mean age, the course of disease 1 ~ 3 year; Matched group man 21 example, female 14 example, 30 ~ 68 years old age, 47.9 years old mean age, the course of disease 1 ~ 3 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) have palpitation, breathe hard, sense of discomfort is felt oppressed in pareordia; 2) percussion: presternum aorta posterior dullness area is broadening, second sound of aortic area is hyperfunction; 3) color echocardiography shows: aortosclerosis, ascending aorta are slightly broadening.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.8 weeks courses for the treatment of.
The oral Atorvaststin of matched group (Beijing Jia Lin pharmaceutical Co. Ltd), takes according to its description.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape are clearly better, angina pectoris, arrhythmia, myocardial ischemia occur obviously to reduce, and blood fat, blood pressure, Hemorheology inspection are normal;
Effective: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape have certain improvement, angina pectoris, arrhythmia, myocardial ischemia occur to reduce to some extent, and blood fat, blood pressure, Hemorheology inspection transfer attention to by danger;
Invalid: patient breathes hard, chest pain, uncomfortable in chest, dizzy, cardio palmus shape without improvement, angina pectoris, arrhythmia, myocardial ischemia often occur, and do not change even aggravation before blood fat, blood pressure, Hemorheology inspection and treatment.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Effective | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 40 | 17 | 20 | 3 | 92% | 0 |
| Matched group | 35 | 9 | 18 | 8 | 70% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment arteriosclerosis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, daily once.
Specific embodiment 3
Take: Rhizoma Acori Graminei 8 grams, Rhizoma Alismatis 7 grams, Herba Artemisiae Scopariae 13 grams, Pollen Typhae 8 grams, Radix Achyranthis Bidentatae 7 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of arteriosclerosis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. be used for the treatment of an arteriosclerotic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts.
2. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of arteriosclerotic Chinese medicine as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Acori Graminei 8 parts, Rhizoma Alismatis 7 parts, Herba Artemisiae Scopariae 13 parts, Pollen Typhae 8 parts, Radix Achyranthis Bidentatae 7 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410622326.8A CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410622326.8A CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
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| Publication Number | Publication Date |
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| CN104288392A true CN104288392A (en) | 2015-01-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410622326.8A Pending CN104288392A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicine for treating atherosclerosis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547780A (en) * | 2015-02-09 | 2015-04-29 | 王士国 | Drug for treating chronic arteriosclerosis caused by hyperlipidemia and preparation thereof |
| CN105250979A (en) * | 2015-11-20 | 2016-01-20 | 王秀娟 | Traditional Chinese medicine pills for treating atherosclerosis and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1669488A (en) * | 2005-03-29 | 2005-09-21 | 张雪晴 | Formula of health beverage |
| CN1682936A (en) * | 2005-02-25 | 2005-10-19 | 石家庄四药有限公司 | Medicinal composition for treating hyperlipemia and its preparing method |
| CN102772491A (en) * | 2012-08-17 | 2012-11-14 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating lower extremity atherosclerotic disease and application of composition |
| CN103768297A (en) * | 2014-01-15 | 2014-05-07 | 解程 | Traditional Chinese medicine for treating hyperlipoidemia |
-
2014
- 2014-11-07 CN CN201410622326.8A patent/CN104288392A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682936A (en) * | 2005-02-25 | 2005-10-19 | 石家庄四药有限公司 | Medicinal composition for treating hyperlipemia and its preparing method |
| CN1669488A (en) * | 2005-03-29 | 2005-09-21 | 张雪晴 | Formula of health beverage |
| CN102772491A (en) * | 2012-08-17 | 2012-11-14 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating lower extremity atherosclerotic disease and application of composition |
| CN103768297A (en) * | 2014-01-15 | 2014-05-07 | 解程 | Traditional Chinese medicine for treating hyperlipoidemia |
Non-Patent Citations (1)
| Title |
|---|
| 周立群等: "《国际中医药现代研究96首届国际中医药杰出成果交流展示会论文集-中英文对照》", 31 May 1996, 中国中医药出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547780A (en) * | 2015-02-09 | 2015-04-29 | 王士国 | Drug for treating chronic arteriosclerosis caused by hyperlipidemia and preparation thereof |
| CN105250979A (en) * | 2015-11-20 | 2016-01-20 | 王秀娟 | Traditional Chinese medicine pills for treating atherosclerosis and preparation method thereof |
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Application publication date: 20150121 |
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