CN104547707A

CN104547707A - Traditional Chinese medicine composition for treating increased intracranial pressure and preparation method thereof

Info

Publication number: CN104547707A
Application number: CN201510023773.6A
Authority: CN
Inventors: 韩军
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-01-19
Filing date: 2015-01-19
Publication date: 2015-04-29

Abstract

The invention discloses a traditional Chinese medicine composition for treating increased intracranial pressure. The traditional Chinese medicine composition consists of Indian buead, plantain seed, seed of pepperweed, lalang grass rhizome, oriental waterplantain rhizome, agaric, milkvetch root, prepared common monkshood daughter root, talc, kudzuvine root, white mulberry root-bark, medicinal cyathula root, platycladi seed, Chinese rhubarb, bamboo shavings, pinellia tuber, reddle, suberect spatholobus stem, szechuan lovage rhizome, dahurian angelica root, rhizoma amorphophalli and white ramping fumitory according to certain weight proportions. The traditional Chinese medicine composition disclosed by the invention has the effects of clearing dampness and promoting diuresis, inducing diuresis and removing swelling, and nourishing the heart and calming the nerves, and can be used for effectively treating increased intracranial pressure.

Description

A kind of Chinese medicine composition for the treatment of increased intracranial pressure and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of increased intracranial pressure.The invention still further relates to the preparation method of this Chinese medicine composition.

Background technology

Normal person's intracranial has certain pressure, is called intracranial pressure (be called for short cranium pressure), typically refers under the state that decubtus, health are lax, pressure measured by the pipe connecting certain internal diameter through lumbar puncture, because of and be referred to as cerebrospinal pressure definitely.When lateral position measures the average cerebrospinal pressure of adult more than 1.96kPa (suitable 200mm water column), be called increased intracranial pressure.Increased intracranial pressure is one group of syndrome that clinical common numerous disease has.Increased intracranial pressure is neurosurgery common clinical pathological syndrome, the common signs such as craniocerebral injury, the cerebral tumor, cerebral hemorrhage, hydrocephalus and intracranial inflammation, because above-mentioned disease makes cranial cavity content volume increase, intracranial pressure is caused to continue at 2.0kPa(200mmH2O) more than, thus the corresponding syndrome caused, be called increased intracranial pressure.Increased intracranial pressure is neurosurgery modal major issue clinically, and symptoms of intracranial hypertension and sign, often appear in the especially patient of intracranial spaceoccupying lesion.Increased intracranial pressure can cause cerebral hernia crisis, and patient can be made dead because of respiratory and circulatory failure.The clinical symptoms of increased intracranial pressure for principal character, also can have the symptom such as giddy, tinnitus, dysphoria, drowsiness, epilepsy, abducens paralysis, diplopia with headache, vomiting, papilloedema.Changes of vital signs is had: blood pressure raises, pulse and breathe slack-off when intracranial hypertension is serious, blood pressure rising is the compensation of regulatory mechanism, to maintain brain blood supply, breathing may be caused by medullary respiratory center dysfunction slowly, changes of vital signs is the dangerous sign of increased intracranial pressure, watch out for the generation of cerebral hernia.

The medicine being used for the treatment of increased intracranial pressure is at present mainly the osmotic diuretics such as mannitol, or note hormone medicine, these medicines not only consumption are large, need rapid intravenous drop, and owing to increasing circulation volume, cardiac load is increased, totally unfavorable to the patient of core function badness, make great misery to the body & mind of patient.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has determined curative effect for treatment increased intracranial pressure, and cheap, treatment time is short, the feature had no side effect.

Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment increased intracranial pressure.

Inventor is in clinical treatment practice for many years, observe the misery that increased intracranial pressure brings to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of increased intracranial pressure repeatedly, the present invention selects Poria, Semen Plantaginis, Semen Lepidii (Semen Descurainiae), Rhizoma Imperatae, Rhizoma Alismatis, Polyporus, the Radix Astragali, Radix Aconiti Lateralis Preparata, Talcum, Radix Puerariae, Cortex Mori, Radix Cyathulae, Semen Platycladi, Radix Et Rhizoma Rhei, Caulis Bambusae In Taenia, the Rhizoma Pinelliae, Haematitum, Caulis Spatholobi, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Amorphophalli, Rhizoma Corydalis combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is promoting diuresis to eliminate damp pathogen, inducing diuresis to remove edema, effect of tranquilizing by nourishing the heart, thus effectively can treat increased intracranial pressure.

The effect of Chinese medicine of the present invention:

Wherein:

Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Nature and flavor: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Sweet the providing additional supplies of this product is oozed, and not only mends but also sharp, and effect is gentle, and property is flat and partially without cold and heat, is the key medicine of promoting diuresis to eliminate damp pathogen.Treatment water wet the edema of expert time, often join Rhizoma Alismatis, Polyporus.Poria decoct has obvious sedation." modality ": " cure mainly Ji Rou Shun muscle of throbbing with fear cautious, dizziness agitation is controlled on side." this product is by heart-spleen boosting and tranquilizing mind.Be used for deficiency of both the heart and spleen, the irritability of insufficiency of vital energy and blood.

Semen Plantaginis: be the dry mature seed of Plantaginaceae plant Herba Plantaginis Plantago asiatica L. or Plantago depressa Willd Plantago depressa Willd..Nature and flavor: sweet, are slightly cold.Return liver, kidney, lung, small intestine meridian.Effect: clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.Control diarrhea due to damp-heat, disease feelings the lighter, can use by single, comparatively severe one can join Poria, Polyporus, Rhizoma Alismatis, Semen Coicis is equivalent uses.Be used for the treatment of antihypertensive effect at present clinically better, also there is obvious diuresis.

Semen Lepidii (Semen Descurainiae): be the dry mature seed of crucifer Lepidium sativum L. Lepidium apetalum Willd. or descurainia sophia (l.) webb ex prantl Descurainia sophia (L.) Webb ex prantl.Nature and flavor: pungent, bitter, Great Cold.Return lung, urinary bladder channel.Effect: eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema." Bencao Jingshu ": Semen Lepidii is the positive medicine of meridian of Hand-TAI YIN, thus Zhong Jing eliminating the pathogens from the lung soup with it, also start with sun bright, meridian of Foot-TAI YANG.The lung belonging to metal, main fur, bladder belongs to water, hides body fluid, and then bladder is with here for obstruction of lung-QI, and it is obstructed that the upper orifices of example closes then lower orifices, and lower orifices are obstructed, then water is wet overflows for dyspnea with fullness of the chest, for swelling, for gathering, all diease occurrences.Pungent energy falls apart, and hardship can be let out, and Great Cold is heavy cloudy can descendingly relieve oedema or abdominal distension through diuresis or purgation, thus can treat " herbal classic " lead all diseases.

Rhizoma Imperatae: be the rhizome of grass perennial herb Herba Imperatae Imperata cylindrica.Nature and flavor: sweet, cold.Return lung, stomach, urinary bladder channel.Effect: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema." Bencao Jingshu " is recorded: impairment caused by overstrain void is won, must interior-heat, and Rhizoma Imperatae is sweet can spleen reinforcing, sweet, though cold and do not violate stomach.Gan Hanneng is except interior-heat, therefore main impairment caused by overstrain void is won.Strengthening the spleen so invigorating middle warmer, heat extraction so QI invigorating, the beneficial blood of sweet energy, heat in blood is the stasis of blood then, and the stasis of blood is then closed, and closes then cold and heat and does, cold and cool blood, sweet beneficial blood, heat go then blood and, and then stagnation resolvation and close logical, general rule cold and heat are from only also.Dysuria, due to interior-heat also, pyrolysis then just diarrhea.Pouring person, caused by blood system deficiency-heat also, removing heat from blood benefit blood, then drench spontaneous recovery, and the exopathogenic heat of the intestines and stomach is explained by oneself, and body fluid is raw and yearningly also stop.Blood stored in the liver and main muscle, cool liver of enriching blood, then muscle is hard.Heat in blood then collapses, and removing heat from blood and blood, then collapse spontaneous recovery.Heat in blood is absurd row then, overflow upper orifices for telling, for coughing up, be epistaxis, bleeding from the gum, removing heat from blood and blood, then all cards are from removing.Strengthening the spleen invigorating middle warmer, diuresis.

Rhizoma Alismatis: be the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..Nature and flavor: sweet, cold.Return kidney, urinary bladder channel.Effect: diuresis, clearing away damp-heat.For edema, the dysuria of retention of water-damp in the body.This product enters kidney, urinary bladder channel, and kind clear damp-heat in lower-JIAO cold in nature, is used for syndrome of dampness-heat in lower jiao.Rhizoma Alismatis has significant diuresis, can promote muriatic excretion, increases urine volume, more obvious to nephritis patient diuresis, has blood pressure lowering, hypoglycemic activity, also has lipotropic effect.

Polyporus: be the dry sclerotia of On Polyporaceae Polyporus Polyporus umbellatus (Pers.) Fries.Nature and flavor: sweet, light, flat.Return kidney, urinary bladder channel.Effect: promoting diuresis to eliminate damp pathogen.Polyporus and Poria compatibility, Polyporus specializes in promoting diuresis to eliminate damp pathogen, and diuretic effect is strong in Poria, and Poria is not only mended but also sharp, and holding concurrently can spleen invigorating mind calming.

The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.This product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.Invigorating the spleen and replenishing QI is good at by the Radix Astragali, is the key medicine of tonifying Qi and lifting yang, and QI invigorating diuresis, to subside a swelling.

Radix Aconiti Lateralis Preparata: be the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..Nature and flavor are pungent, sweet, hot greatly; Poisonous.GUIXIN, kidney, spleen channel.Effect: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain.This product is hot dry strong, walks and does not keep, and can pass through 12 warps, can chase after again lost YANG-depletion, the Yuanyang of deficiency can be subsidized again, use same with tonic, the card that all over the body up and down yang-energy is on the decline, yin-cold excess can be controlled, can on help heart-yang to promote blood circulation, middle warming the spleen sun is with strong fortune, and lower the kidney warming sun is fiery with benefit, deficiency of spleen-YANG and kidneyYANG.

Talcum: be silicates mineral talc race Talcum, main containing hydrous magnesium silicate ［ Mg3(Si4O10) (OH) 2 ］.Nature and flavor: sweet, light, cold.Return bladder, lung, stomach warp.Effect: inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore.For pyretic stranguria, stranguria caused by urinary stone, urinates hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea; External treatment eczema, eczema, miliaria.For the damp and hot watery diarrhea caused, Poria, Semen Coicis, the equivalent use of Semen Plantaginis can be coordinated.

Radix Puerariae: be the dry root of legume pueraria lobata Pueraria lobata (Willd.) Ohwi.Nature and flavor are cool, sweet, pungent.Enter spleen, stomach warp.Effect: induce sweat and bring down a fever, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Radix Puerariae is sweet pungent cool in nature, and lightly floating, it is loose to rise, and enters taste warp, has relieving the exterior syndrome by diaphoresis, the merit of expelling pathogenic factors from muscles for reducing heat.Modern pharmacology research shows that the flavone proposed in Radix Puerariae can increase brain and crown vascular flow amount, all has protective effect to the heart ischemia reaction caused by pituitrin.Clinical practice is used for the treatment of coronary heart diseases and angina pectoris and has a significant effect.

Cortex Mori: be the dry root bark of moraceae plants Mulberry Morus alba L..Nature and flavor: sweet, cold.Return lung meridian.Effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.Lung qi, regulating fluid apssage and inducing diuresis to remove edema can fall clearly in this product, with controlling hydrosarca, dysuria, edema of the face person.

Radix Cyathulae: be the dry root of amaranthaceous plant Radix Cyathulae Cyathula officinalis Kuan.Nature and flavor: sweet, micro-hardship, flat.Return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Semen Platycladi: be the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladus orientalis (L.) Franco.Nature and flavor: sweet are flat.GUIXIN, kidney, large intestine channel.Effect: tranquilizing by nourishing the heart, hidroschesis, intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." medicineization justice ": Semen Platycladi, the saturating heart of fragrance, body profit grows blood.Same Poria cum Radix Pini, Semen Ziziphi Spinosae, the Radix Rehmanniae, Radix Ophiopogonis, be product clear in turbid, cure mainly mind void timid, palpitation with fear palpitation with a distress feeling, color is wan and sallow, skin pruritus due to dryness, and the merit of the blood that all nourishes heart also.Get again abnormal smells from the patient all dense, return kidney in turbid, same to Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Fructus Lycii, Radix Achyranthis Bidentatae, be packing bone marrow, cure mainly damage of kidney-YIN, the heavy pain in back, sufficient knee joint is weak, and night sweat due to yin deficiency, the power that all nourishing kidney is dry also.Sweet in the mouth also can delay liver, the deficiency of tonifying liver gallbladder, extremely reliable, but the flat power of property delay, should be multiplex be wonderful.

Radix Et Rhizoma Rhei: be polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheum tanguticum Maxim ex Balf.Or Rheum officinale Rheum officinale Baill.Dry root and rhizome.Nature and flavor: bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Effect: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.

Caulis Bambusae In Taenia: be the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro Bambusa tuldoides Munro, major part allusion quotation bamboo Sinocalamus beecheyanus (Munro) McClure var. pubescens P. F. Li or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle Phyllostachys nigra (Lodd.) Munro var. henonis (Mitf.) Stapf ex Rendle.Nature and flavor: sweet, are slightly cold.Enter lung, stomach, gallbladder meridian.Effect: clearing away heat to stop vomiting, clearing away phlegm dissipating depression of QI.Caulis Bambusae In Taenia and the Rhizoma Pinelliae, two medicines all have reduce phlegm, preventing or arresting vomiting, sedative action, peaceful for the unhappiness caused by milk-livered expectorant heat stagnation knot, have a dizzy spell, card that the sound of vomiting is vomitted in regurgitation, often refinforce each other, reduce phlegm to work in coordination with, calm the nerves, preventing or arresting vomiting effect.

The Rhizoma Pinelliae: be the tuber at the Rhizoma Arisaematis section plant Rhizoma Pinelliae (Pinellia ternata (Thunb.) Breit.).Nature and flavor: pungent, temperature, poisonous.Enter spleen, stomach warp.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.The pungent loose warm-dryness syndrome of these product is poisonous, main enter taste double enter lung, water of manageing it wets, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling.Water is wet to be gone, and the strong and sputum of spleen is from disappearing, and inverse gas falls then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass.Both cure mainly the abundant expectoration cough with asthma QI rising in reverse order of spleen damp-phlegm heap soil or fertilizer over and around the roots, control again the dizzy palpitation and insomnia that damp-phlegm is violated." property of medicine opinion ": expectorant saliva, appetite promoting and the spleen strengthening, anti-nausea, go expectorant in the heart full, lower lung qi, master coughs knot.New survivor rub be coated with carbuncle do not disappear, can tumor wart be removed.

Haematitum: be the Ore of oxide-based mineral bloodstone Haematite.Nature and flavor: bitter, sweet; Flat; Cold; Nontoxic.Return liver; Stomach; Heart channel.Effect: suppressing the hyperactive liver and subsiding YANG; Important city sending down the abnormal ascending QI; Cooling blood for hemostasis.Main headache; Dizzy; Cardiopalmus; Demented; Infantile convulsion; Vomiting; Eructation; Singultus; Dysphagic; Cough; Asthma; Spit blood; Epistaxis; Metrorrhagia; Have blood in stool; Hematuria." Changsha medicine solution ": drive turbid undershoot, falls the inverse gas taking the photograph lung stomach, lets out restlessness with depression except the sound of vomiting, only regurgitation vomiting, treat palpitation with fear asthma.

Caulis Spatholobi: be the dry rattan of pulse family Leguminosae plant spatholobus suberectus Spatholobus suberec tusDunn.Nature and flavor: bitter, sweet, temperature.Return liver, kidney channel.Effect: enrich blood, invigorates blood circulation, dredging collateral.This product promoting the circulation of blood is nourished blood, relaxing muscles and tendons and activating QI and blood in the collateral, for treatment passages through which vital energy circulates is not smooth, and the common medicine of channels discord disease.Control apoplexy numb hand and foot, quadriplegia, Chang Peiwu benefiting QI for activating blood circulation dredging collateral medicine, as the medicine such as the Radix Astragali, Rhizoma Chuanxiong.

Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.Rhizoma Chuanxiong has obvious sedation.The in vitro testses such as antibacterial action: Rhizoma Chuanxiong has inhibitory action to large intestine, dysentery (Song Nei Shi), distortion, green pus, typhoid fever, Salmonella paratyphi and vibrio cholera etc.Rhizoma Chuanxiong water logging agent (1:3) also has inhibitory action to some pathogenic dermatophytes in vitro.

The Radix Angelicae Dahuricae: be the dry root of samphire Radix Angelicae Dahuricae Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. or Radix angelicae dahuricae Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var.formosana (Boiss.) Shan et Yuan.Nature and flavor: pungent, warm.Attach to the lung and stomach meridians.Effect: expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.For headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.Water decoction to escherichia coli, adopt Shigella flexneri, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, Bacillus proteus, vibrio cholera, human body tubercule bacillus etc. and have inhibitory action." book on Chinese herbal medicine is looked for the truth ": the Radix Angelicae Dahuricae, temperature power is thick, sensible row table, is Foot yangming Channel expelling pathogenic wind and eliminating dampness principal agent.Therefore all diseases of energy all women's head-ornaments of Zhi Yangming, as head's dusk pain, supraorbital bone pain, and gingiva osteodynia, dark complexion scar defect person is also.And its wind heat takes advantage of lung, on sparkle in brain, ooze for deep tears; Move in large intestine, become metrorrhagia blood and close, hemorrhoidal hamorrhage hemorrhoid complicated by anal fistula carbuncle; Wind and damp and hot, sends out in skin, becomes skin infection pruritus due to dryness; All loose solution of temperature can hold in the palm, and the wind of space between skin and muscles is known, stay the carbuncle of knot to dive and disappear, reach on really dispeling the wind, wet dissipation fire wants agent also.

Rhizoma Amorphophalli: be Araeceae Amorphophallus plant Rhizoma amorphophalli Anorphophallus konjac K. Koch, be used as medicine with spherical tuber.Nature and flavor: pungent, cold.Poisonous.Effect: dispersing swelling and dissipating binds, removing toxic substances pain relieving.For tumor, lymphoid tuberculosis; Carbuncle furuncle and phyma poison is controlled in external, venom.

Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang.Nature and flavor: acrid, bitter, warm.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.The pungent loose temperature of this product is led to, the stagnation of QI in energy promoting the circulation of blood, stasis in gas, blood-activating and qi-promoting pain relieving, and the kind multiple pain controlled caused by stagnation of QI and blood, its analgesic effect is excellent.

Side's solution of the present invention is: Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming in side, Semen Plantaginis clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, Semen Lepidii (Semen Descurainiae) inducing diuresis to remove edema, Rhizoma Imperatae, Rhizoma Alismatis cooling blood for hemostasis, clearing away heat and promoting diuresis, Polyporus promoting diuresis to eliminate damp pathogen, above Six-element is monarch drug altogether, promoting diuresis to eliminate damp pathogen is carried out to the health of patient, the pressure of reduction of patient intracranial, carries out symptomatic treatment from the of symptom own, solves the clinical symptoms of patient with the fastest speed.Radix Astragali inducing diuresis to remove edema, tune waterway, Radix Aconiti Lateralis Preparata recuperating depleted YANG and rescuing the patient from collapse, dispersing cold for relieving pain, Talcum inducing diuresis for treating stranguria syndrome, Radix Puerariae induces sweat and brings down a fever, Cortex Mori inducing diuresis to remove edema, Radix Cyathulae easing joint movement, inducing diuresis for treating stranguria syndrome, Semen Platycladi tranquilizing by nourishing the heart, above seven tastes are ministerial drug altogether, and drug effect is assisted a ruler in governing a country the effect that monarch drug increases promoting diuresis to eliminate damp pathogen, also there is the effect of dispersing cold for relieving pain, tranquilizing by nourishing the heart, what reduction of patient was brought because of increased intracranial pressure feel sick, the symptom such as headache.Radix Et Rhizoma Rhei eliminating blood stasis and inducing menstruation, Caulis Bambusae In Taenia clearing away phlegm dissipating depression of QI, Rhizoma Pinelliae drying dampness to eliminate phlegm, dissolving lump and resolving mass, Haematitum important city sending down the abnormal ascending QI, Caulis Spatholobi is enriched blood and invigorates blood circulation, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Radix Angelicae Dahuricae expelling wind and cold, understand things pain-stopping, Rhizoma Amorphophalli dispersing swelling and dissipating binds, Rhizoma Corydalis blood circulation promoting regulates qi, above a few taste is adjuvant drug altogether, add the effect of dispersing cold for relieving pain, heat-clearing and toxic substances removing, reduce the edema of intracranial, alleviate the symptom such as headache, epilepsy that increased intracranial pressure brings, thus reach the effect of disease therapy.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has promoting diuresis to eliminate damp pathogen, inducing diuresis to remove edema, effect of tranquilizing by nourishing the heart, effectively can treat increased intracranial pressure.

Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Poria 25-35 part, Semen Plantaginis 15-25 part, Semen Lepidii (Semen Descurainiae) 4-14 part, Rhizoma Imperatae 19-29 part, Rhizoma Alismatis 15-25 part, Polyporus 13-23 part, Radix Astragali 45-55 part, Radix Aconiti Lateralis Preparata 7-17 part, Talcum 19-29 part, Radix Puerariae 7-17 part, Cortex Mori 7-17 part, Radix Cyathulae 13-23 part, Semen Platycladi 10-20 part, Radix Et Rhizoma Rhei 4-14 part, Caulis Bambusae In Taenia 7-17 part, Rhizoma Pinelliae 4-14 part, Haematitum 15-25 part, Caulis Spatholobi 13-23 part, Rhizoma Chuanxiong 7-17 part, Radix Angelicae Dahuricae 7-17 part, Rhizoma Amorphophalli 10-20 part, Rhizoma Corydalis 10-20 part.

Wherein be preferably: 30 parts, Poria, Semen Plantaginis 20 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Rhizoma Imperatae 24 parts, Rhizoma Alismatis 20 parts, Polyporus 18 parts, the Radix Astragali 50 parts, Radix Aconiti Lateralis Preparata 12 parts, 24 parts, Talcum, Radix Puerariae 12 parts, Cortex Mori 12 parts, Radix Cyathulae 18 parts, Semen Platycladi 15 parts, Radix Et Rhizoma Rhei 9 parts, Caulis Bambusae In Taenia 12 parts, the Rhizoma Pinelliae 9 parts, Haematitum 20 parts, Caulis Spatholobi 18 parts, Rhizoma Chuanxiong 12 parts, the Radix Angelicae Dahuricae 12 parts, Rhizoma Amorphophalli 15 parts, Rhizoma Corydalis 15 parts.

Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.

The preferred preparation method of the present invention is granule, and its preparation method is as follows:

Step one: by weight proportion of the present invention, first becomes medicated bag by Semen Plantaginis, Semen Lepidii (Semen Descurainiae), Semen Platycladi bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;

Step 2: by weight proportion of the present invention, grinds to 180 mesh sieves by Poria, Polyporus, for subsequent use;

Step 3: by weight proportion of the present invention, by Talcum, Haematitum is suitably pulverized, bind up with gauze, put into after marmite adds step one immersion and remain cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Rhizoma Imperatae is added, the Radix Astragali, Radix Aconiti Lateralis Preparata, Radix Puerariae, Cortex Mori, Radix Cyathulae, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, medicated bag in the Radix Angelicae Dahuricae and step one decocts 45 minutes, add Rhizoma Alismatis afterwards, Caulis Bambusae In Taenia, the Rhizoma Pinelliae, Caulis Spatholobi, Rhizoma Amorphophalli, Rhizoma Corydalis decocts filtration in 30 minutes, obtain filtrate, merge twice filtrate, filter, waste, merge twice filtrate, and when filtrate being concentrated into about 80 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, for subsequent use,

Step 4: step 2 gained fine powder is added in step 3 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 15g/ bag, every bag of granule containing crude drug 7g.

Medicine of the present invention has promoting diuresis to eliminate damp pathogen, inducing diuresis to remove edema, the effects such as tranquilizing by nourishing the heart, and determined curative effect, cheap, treatment time is short, have no side effect, the mode that this Chinese medicine preparation adopts treats the side effect that diuretic can be avoided to bring patient, accelerates the improvement of the state of an illness.According to clinical 160 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 90%, two the total effective rate course for the treatment of 97.5%.

Detailed description of the invention

Embodiment one, 25 parts, Poria, Semen Plantaginis 15 parts, Semen Lepidii (Semen Descurainiae) 4 parts, Rhizoma Imperatae 19 parts, Rhizoma Alismatis 15 parts, Polyporus 13 parts, the Radix Astragali 45 parts, Radix Aconiti Lateralis Preparata 7 parts, 19 parts, Talcum, Radix Puerariae 7 parts, Cortex Mori 7 parts, Radix Cyathulae 13 parts, Semen Platycladi 10 parts, Radix Et Rhizoma Rhei 4 parts, Caulis Bambusae In Taenia 7 parts, the Rhizoma Pinelliae 4 parts, Haematitum 15 parts, Caulis Spatholobi 13 parts, Rhizoma Chuanxiong 7 parts, the Radix Angelicae Dahuricae 7 parts, Rhizoma Amorphophalli 10 parts, Rhizoma Corydalis 10 parts.

Embodiment two, 30 parts, Poria, Semen Plantaginis 20 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Rhizoma Imperatae 24 parts, Rhizoma Alismatis 20 parts, Polyporus 18 parts, the Radix Astragali 50 parts, Radix Aconiti Lateralis Preparata 12 parts, 24 parts, Talcum, Radix Puerariae 12 parts, Cortex Mori 12 parts, Radix Cyathulae 18 parts, Semen Platycladi 15 parts, Radix Et Rhizoma Rhei 9 parts, Caulis Bambusae In Taenia 12 parts, the Rhizoma Pinelliae 9 parts, Haematitum 20 parts, Caulis Spatholobi 18 parts, Rhizoma Chuanxiong 12 parts, the Radix Angelicae Dahuricae 12 parts, Rhizoma Amorphophalli 15 parts, Rhizoma Corydalis 15 parts.

Embodiment three, 35 parts, Poria, Semen Plantaginis 25 parts, Semen Lepidii (Semen Descurainiae) 14 parts, Rhizoma Imperatae 29 parts, Rhizoma Alismatis 25 parts, Polyporus 23 parts, the Radix Astragali 55 parts, Radix Aconiti Lateralis Preparata 17 parts, 29 parts, Talcum, Radix Puerariae 17 parts, Cortex Mori 17 parts, Radix Cyathulae 23 parts, Semen Platycladi 20 parts, Radix Et Rhizoma Rhei 14 parts, Caulis Bambusae In Taenia 17 parts, the Rhizoma Pinelliae 14 parts, Haematitum 25 parts, Caulis Spatholobi 23 parts, Rhizoma Chuanxiong 17 parts, the Radix Angelicae Dahuricae 17 parts, Rhizoma Amorphophalli 20 parts, Rhizoma Corydalis 20 parts.

Here is the clinical statistics data that patient uses medicine of the present invention:

One, physical data

Accept out-patient 160 example for medical treatment, wherein male 73 example, women 87 example, 40 years old mean age.

Two, Therapeutic Method:

Observation group is according to Medications Example two of the present invention, and the granule that preferred preparation method is made, and boiled water is taken after mixing it with water, every day 3 times, each one bag, within 3 days, is a course for the treatment of.

Three, efficacy assessment standard

1, cure: intracranial pressure is normal, and other clinical symptoms, sign also disappear completely.

2, take a turn for the better: intracranial pressure is controlled, and other clinical symptoms are eased.

3, do not heal: increased intracranial pressure and clinical symptoms are without any improvement.

Four, therapeutic outcome statistics

Wherein: total effective rate=cure rate+improvement rate

Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness in treatment increased intracranial pressure, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.

Model case and curative effect:

Case one, grandson, female, 40 years old, patient threw from stair accidentally, go into a coma at once, patient injury's mechanism is not clear, after injured several disappearance, revives, occur the symptoms such as vomiting, waist wears inspection, increased intracranial pressure, and patient's heart function is bad, diuretic can not be used, made granule in the rear employing embodiment of the present invention two, after patient takes a course for the treatment of, sensory symptoms obviously alleviates, and intracranial pressure is controlled, and patient continues to take a course for the treatment of, waist wears inspection, and intracranial pressure is normal, recovery from illness.

Case two, Bai, man, 60 years old, always there is symptoms such as having a headache, feel sick in the recent period, have history of hypertension, patient removes examination in hospital, find that intracranial is pressed with the phenomenon increased, patient's hospitalization several days effects are not clearly, after being introduced, carry out here treatment, adopt made granule in the embodiment of the present invention two, after patient takes a course for the treatment of, symptom obviously alleviates, the mental status also takes a turn for the better to some extent, headache, the symptom of feeling sick are eased, and continue to take a course for the treatment of, and patient feels do not have uncomfortable sensation, waist wears check result intracranial pressure normally, recovery from illness.

Case three, Korea Spro, female, 57 years old, suffers from cerebroma, occur after operation that intracranial is pressed with the symptom increased, patient adopts made granule in the embodiment of the present invention two, and after patient takes a course for the treatment of, symptom obviously alleviates, headache, the symptom of feeling sick are eased, continue to take a course for the treatment of, waist wears check result intracranial pressure normally, recovery from illness.

Claims

1. treat the Chinese medicine composition of increased intracranial pressure for one kind, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Poria 25-35 part, Semen Plantaginis 15-25 part, Semen Lepidii (Semen Descurainiae) 4-14 part, Rhizoma Imperatae 19-29 part, Rhizoma Alismatis 15-25 part, Polyporus 13-23 part, Radix Astragali 45-55 part, Radix Aconiti Lateralis Preparata 7-17 part, Talcum 19-29 part, Radix Puerariae 7-17 part, Cortex Mori 7-17 part, Radix Cyathulae 13-23 part, Semen Platycladi 10-20 part, Radix Et Rhizoma Rhei 4-14 part, Caulis Bambusae In Taenia 7-17 part, Rhizoma Pinelliae 4-14 part, Haematitum 15-25 part, Caulis Spatholobi 13-23 part, Rhizoma Chuanxiong 7-17 part, Radix Angelicae Dahuricae 7-17 part, Rhizoma Amorphophalli 10-20 part, Rhizoma Corydalis 10-20 part.

2. the Chinese medicine composition of the treatment increased intracranial pressure according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: 30 parts, Poria, Semen Plantaginis 20 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Rhizoma Imperatae 24 parts, Rhizoma Alismatis 20 parts, Polyporus 18 parts, the Radix Astragali 50 parts, Radix Aconiti Lateralis Preparata 12 parts, 24 parts, Talcum, Radix Puerariae 12 parts, Cortex Mori 12 parts, Radix Cyathulae 18 parts, Semen Platycladi 15 parts, Radix Et Rhizoma Rhei 9 parts, Caulis Bambusae In Taenia 12 parts, the Rhizoma Pinelliae 9 parts, Haematitum 20 parts, Caulis Spatholobi 18 parts, Rhizoma Chuanxiong 12 parts, the Radix Angelicae Dahuricae 12 parts, Rhizoma Amorphophalli 15 parts, Rhizoma Corydalis 15 parts.

3. the Chinese medicine preparation for the treatment of increased intracranial pressure according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is granule.

4. treat a preparation method for the Chinese medicine preparation of increased intracranial pressure, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, first Semen Plantaginis, Semen Lepidii (Semen Descurainiae), Semen Platycladi bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use; Step 2: by weight proportion of the present invention, grinds to 180 mesh sieves by Poria, Polyporus, for subsequent use;

Step 3: by weight proportion of the present invention, by Talcum, Haematitum is suitably pulverized, bind up with gauze, put into after marmite adds step one immersion and remain cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Rhizoma Imperatae is added, the Radix Astragali, Radix Aconiti Lateralis Preparata, Radix Puerariae, Cortex Mori, Radix Cyathulae, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, medicated bag in the Radix Angelicae Dahuricae and step one decocts 45 minutes, add Rhizoma Alismatis afterwards, Caulis Bambusae In Taenia, the Rhizoma Pinelliae, Caulis Spatholobi, Rhizoma Amorphophalli, Rhizoma Corydalis decocts filtration in 30 minutes, obtain filtrate, merge twice filtrate, filter, waste, merge twice filtrate, and when filtrate being concentrated into about 80 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, for subsequent use, step 4: step 2 gained fine powder is added in step 3 gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 15g/ bag, every bag of granule containing crude drug 7g.