CN106361918A - Traditional Chinese medicine patch for treating deficiency of kidney-yang - Google Patents

Traditional Chinese medicine patch for treating deficiency of kidney-yang Download PDF

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CN106361918A
CN106361918A CN201611081493.1A CN201611081493A CN106361918A CN 106361918 A CN106361918 A CN 106361918A CN 201611081493 A CN201611081493 A CN 201611081493A CN 106361918 A CN106361918 A CN 106361918A
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kidney
minutes
yang
thick paste
chinese medicine
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侯江红
张文放
赵广森
柏贞
石达
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/10Peat; Amber; Turf; Humus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention relates to a traditional Chinese medicine patch for treating deficiency of kidney-yang. The problems that the treatment period of deficiency of kidney-yang is long, cost is high, the treatment effect is poor, and deficiency of kidney-yang cannot be radically treated and is prone to relapse are effectively solved. The traditional Chinese medicine patch is prepared from, by weight, 5-9 g of cynomorium songaricum, 3-9 g of herba epimedii, 10-15 g of radix moridae officinalls, 2-5 g of cortex cinnamomi, 1-2 g of amber, 6-12 g of cornus officinalis, 10-30 g of prepared rehmannia roots and 6-9 g of rhizoma alismatis. During preparation, the raw material medicine is mixed, the mixture is washed with vinegar, the mixture is washed with deionized water and dehydrated, the mixture is put in a dryer to be dried, the mixture is ground into fine powder, ethyl alcohol is added, refluxing is carried out, reflux is collected and filtered, filtrate is obtained, ethyl alcohol is recycled through heating concentration, and extract is obtained; the extract is concentrated into thick paste, the cooled thick paste is evenly spread on plaster cloth, and the patch is obtained. The traditional Chinese medicine patch is convenient to use, short in treatment period, low in cost, remarkable in treatment effect, not prone to relapse and free of toxic and side effects.

Description

A kind of Chinese herbs paste treating insufficiency of kidney-YANG
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese herbs paste treating insufficiency of kidney-YANG.
Background technology
" kidney " in " kidney deficiency " concept that traditional medicine is said, refers not only to kidney anatomically, and is a physiology Effect is quite extensive, has the important dirty of direct or indirect relation with human body reproduction, growth promoter, digestion, endocrine metabolism etc. Device.Show themselves in that hypomnesis, hypomnesis at mental aspect, absent minded, deficient in energy, work efficiency reduces. Show themselves in that unhappy in terms of feelings will, emotion is often difficult to automatic control, dizzy, irritability, irritated, anxiety, depression etc..In sexual function Aspect shows themselves in that sexual function reduces, and man's property interest reduces, and libido reduces, and sexual impotence or penis are lifted and not hard, seminal emission, spermatorrhea, morning Let out, the visible oligospermia of microscopy or motility of sperm lower, sterile.Show themselves in that frequent micturition in terms of urinary system, urine waits, The symptoms such as clear urine in large amounts.Though often having the Chinese medicine announcing treatment insufficiency of kidney-YANG at present, being required for greatly long-term taking can take effect, and controls The treatment cycle is long, high cost, weak curative effect, and can not effect a radical cure, and easily repeatedly, often makes patient lose the confidence it is difficult to adhere to.
Content of the invention
For above-mentioned situation, for overcoming prior art defect, the purpose of the present invention provides a kind of treats insufficiency of kidney-YANG Chinese herbs paste, can effectively solving insufficiency of kidney-YANG treatment cycle long, high cost, weak curative effect, and can not effecting a radical cure, problem easily repeatedly.
The technical scheme that the present invention solves is, by following weight meter: Herba Cynomorii 5~9g, Herba Epimedii 3~9g, Radix Morindae Officinaliss 10- 15g, Cortex Cinnamomi 2-5g, succinum 1~2g, Fructus Corni 6~12g, Radix Rehmanniae Preparata 10-30g and Rhizoma Alismatis 6-9 g make as material medicine;System When standby, above-mentioned raw materials medicament mixed rinses 20-50 minute with the vinegar of 2.5-6.8wt%, reuse 30-40 DEG C go from Sub- water rinses 3-10 minute, drains, puts into drier 15-30 minute, and baking temperature is 55-65 DEG C, grinds to form 20-50 mesh Fine powder, be subsequently adding fine powder 5 times amount concentration be 32-47wt% ethanol, 85-90 DEG C carry out flow back 30-50 minute, receive Fetch flow liquid, filter, obtain filtrate, heating concentration and recovery ethanol obtains extractum;It is the thick of 1.48-1.58g/ml that extractum is condensed into density Cream, thick paste cooling after spread out even in medicated plaster cloth, obtain final product.
The invention has the beneficial effects as follows: easy to use, treatment cycle is short, and low cost is evident in efficacy, and can fundamentally enter Row treatment, the negative and positive of conditioning patient, QI and blood, function, coordinate steady mechanism in body, reach the purpose of " YIN and YANG in a relative equilibrium ", no Easily repeatedly, have no toxic side effect, be that on Chinese medicine creates greatly.
Specific embodiment
With reference to embodiments the specific embodiment of the present invention is elaborated.
Embodiment 1
The present invention is by following weight meter: Herba Cynomorii 9g, Herba Epimedii 3g, Radix Morindae Officinaliss 10g, Cortex Cinnamomi 2g, and succinum 2 g, Fructus Corni 6g are ripe Radix Rehmanniae 10g and Rhizoma Alismatis 9g makes as material medicine;During preparation, above-mentioned raw materials medicament mixed rinses 20 with the vinegar of 2.5wt% Minute, reuse 30 DEG C of deionized water rinsing 3 minutes, drain, put into drier 15 minutes, baking temperature is 55 DEG C, Grind to form the fine powder of 20 mesh, the concentration being subsequently adding fine powder 5 times amount is the ethanol of 32wt%, carries out flowing back 30 minutes at 85 DEG C, Collect backflow, filter, obtain filtrate, heating concentration and recovery ethanol obtains extractum;Extractum is condensed into the thick paste that density is 1.48g/ml, Thick paste cooling after spread out even in medicated plaster cloth, obtain final product.
Embodiment 2
The present invention is by following weight meter: Herba Cynomorii 7g, Herba Epimedii 6g, Radix Morindae Officinaliss 13g, Cortex Cinnamomi 4g, succinum 1.5g, Fructus Corni 8g, Radix Rehmanniae Preparata 20g and Rhizoma Alismatis 8g makes as material medicine;During preparation, by above-mentioned raw materials medicament mixed, with the vinegar punching of 6 .8wt% Wash 50 minutes, reuse 40 DEG C of deionized water rinsing 10 minutes, drain, put into drier 30 minutes, baking temperature is 65 DEG C, then the fine powder of 50 mesh is ground to form with grinder, the concentration being subsequently adding fine powder 5 times amount is the ethanol of 47wt%, at 90 DEG C Carry out flowing back 50 minutes, collect backflow, filter, obtain filtrate, heating concentration and recovery ethanol obtains extractum;Extractum is condensed into density The thick paste of 1.58g/ml, thick paste cooling after spread out even in medicated plaster cloth, obtain final product.
Embodiment 3
The present invention is by following weight meter: Herba Cynomorii 5g, and Herba Epimedii 9g, Radix Morindae Officinaliss 15g, Cortex Cinnamomi 5g, succinum 1g, Fructus Corni 12g are ripe Radix Rehmanniae 30g and Rhizoma Alismatis 6g makes as material medicine;During preparation, above-mentioned raw materials medicament mixed rinses 35 points with the vinegar of 3wt% Clock, reuses 35 DEG C of deionized water rinsing 5 minutes, drains, put into drier 22 minutes, and baking temperature is 60 DEG C, then Grind to form the fine powder of 40 mesh with grinder, the concentration being subsequently adding fine powder 5 times amount is the ethanol of 40wt%, is flowed back at 88 DEG C 40 minutes, collect backflow, filter, obtain filtrate, heating concentration and recovery ethanol obtains extractum;It is 1.50g/ml that extractum is condensed into density Thick paste, thick paste cooling after spread out even in medicated plaster cloth, obtain final product.
The herbal pharmacology effect of inventive formulation raw material is as follows:
Herba Cynomorii: YANG invigorating class Chinese medicine;Nature and flavor: sweet, temperature;Return through: Return liver, kidney, large intestine channel;Effect: kidney-replenishing, benefiting essence-blood, intestine moistening is led to Just;Cure mainly: for impotence involuntary emission, soreness of the waist and knees, muscles and bones is powerless, constipation.Chinese medicine Herba Cynomorii acts on: 1, strengthens immunologic function; 2nd, enhancing body anoxia enduring and stress ability;3rd, loosening bowel to relieve constipation;4th, remove free radical.1st, Chinese medicine Herba Cynomorii energy loosening bowel to relieve constipation.For The withered constipation in dryness of the intestine Tianjin, is often equal to Fructus Cannabiss, Radix Angelicae Sinensis use;Also can be decocted with this product is dense, plus honey receives cream, boiled water or hot alcoholizing Clothes.2nd, the sweet temperature of Chinese medicine Herba Cynomorii, can kidney-replenishing and emerging sun controlling nocturnal emission with astringent drugs.For the sexual impotence caused by insufficiency of kidney-YANG, spermatorrhea, with Semen Cuscutae, Fructus Rosae Laevigatae The tonifying the kidney to consolidate the essence medicine such as son is with use.3rd, the invigorating the liver and kidney of Chinese medicine Herba Cynomorii energy, benefiting essence-blood, moisturize nourishing muscle and tendon and play flaccidity.For deficiency of the liver and kindey, essence and blood Soreness of the waist and knees caused by virtual loss, muscles and bones are powerless, walking hardship or lower extremity paralysiss etc., often be equal to Radix Rehmanniae Preparata, Os Tigriss use, and such as brave dive Ball.
Herba Epimedii: another name Herba Epimedii, YANG invigorating class Chinese medicine, nature and flavor: acrid, sweet, warm;Return through: return liver and kidney channel;Effect: Bu Shen Zhuang Sun, expelling wind and removing dampness;Cure mainly: for impotence due to deficiency of the kidney, weakness of the waist and knees, anemofrigid-damp arthralgia, muscles and bones is ached.Herba Epimedii acts on: 1, strengthens and exempts from Epidemic disease function;2nd, anti-aging effects;3rd, promote organism metabolism;4th, improve cardiac function;5th, improve sexual function, promote gonepoiesis;6、 Sedation.Herba Epimedii pungent-warm dry dissipate, can functions dispelling wind and clearing away cold, removing dampness, again can kidney-replenishing, invigorating yangqi.For anemofrigid-damp arthralgia, especially It is good at treating simultaneous see deficient and weak YANG QI person, the clothes of can alone steeping in wine of anemofrigid-damp arthralgia, or be equal to use with Radix Clematidis, Rhizoma Chuanxiong, such as Herba Epimedii Dissipate.See soreness of bones and muscles, the person of walking with difficulty as simultaneous, be equal to the Cortex Eucommiae, Herba Taxilli use.Herba Epimedii function kidney invigorating and YANG supporting.For Sexual impotence caused by kidney yang deficiency, frequent micturition, weakness of the waist and knees, can alone infusing drugs in wine take, or same with kidney-nourishing yang-strengthening medicines such as Rhizoma Curculiginises, Radix Morindae Officinaliss With.
Radix Morindae Officinaliss: YANG invigorating class Chinese medicine, nature and flavor: pungent, sweet, tepor;Return through: return kidney channel;Effect: reinforcing the kidney and supporting YANG, expelling wind and removing dampness; Cure mainly: for sexual impotence frequent micturition, uterus cold infertile, rheumatic arthralgia.Morinda officinalis How acts on: 1, strengthens immunologic function;2nd, antiinflammatory action; 3rd, improve reproductive system function.Morinda officinalis How can kidney-replenishing, again can wind-damp dispelling.For insufficiency of kidney-YANG, wind-cold damp pathogen is taken advantage of a weak point in opponent's defence And enter, the caused lumbocrural pain of blood vessels numbness resistance, muscle arteries and veins contraction, joint stuffiness and limbs weakness, it is equal to the Cortex Eucommiae, Bi With such as JINGANG WAN.2nd, Morinda officinalis How function reinforcing the kidney and supporting YANG.For the sexual impotence caused by insufficiency of kidney-YANG, woman's uterus cold infertile, with people The adapteds such as ginseng, Rhizoma Dioscoreae.For kidney deficiency incontinence of urine, it is equal to Fructus Alpiniae Oxyphyllae, Ootheca Mantidiss use.Can be additionally used in menoxenia, few abdomen cold Bitterly, it is equal to Rhizoma Alpiniae Officinarum, Cortex Cinnamomi use, such as Morindae Officinalis Pill.
Cortex Cinnamomi: Manganese, nature and flavor: pungent, sweet, heat;Return through: return kidney, spleen, the heart, Liver Channel;Effect: mends fire supporing yang, cold expelling Pain relieving, promoting the flow of QI-blood by warming the meridian;Cure mainly: for insufficiency of kidney-YANG, sexual impotence cold womb, the cold abdomen of gastral cavity abdomen, arthralgia due to cold lumbago, cold hernia stomachache, cold blood stasis, Closed dysmenorrhea, obstruction of qi in the chest and cardialgia.Chinese medicine cinnamon act on, 1, adjust immunologic function;2nd, hypotensive effect;3rd, resisting pathogenic microbes effect; 4th, analgesic activity;5th, sedation;6th, anticonvulsant action;7th, blood coagulation resisting function.Chinese medicine cinnamon temperature can transport yang-energy, goes heavy cold chronic Cold, all inward invasion of pathogenic cold, the card of yang deficiency YIN-cold all can be applied.With controlling coldness and pain in the epigastrium, normal and Rhizoma Zingiberiss, Rhizoma Alpiniae Officinarum, with using, play warming middle-JIAO altogether The work(of dispersing cold for relieving pain.With controlling arthralgia due to cold lumbago, normal and Radix Angelicae Pubescentiss, the compatibility such as Herba Taxilli, with wind-damp dispelling, invigorating the liver and kidney.If cold hernia stomachache, and Normal and the Radix Linderae, Rhizoma Zingiberis Recenss are same to be used, with dim liver dispersing cold for relieving pain, such as nuangan decoction.Chinese medicine cinnamon is hot product, can mend fire from the gater of life, draw Fire return unit and Yiyang disappears the moon, therefore have the work(of mends fire supporing yang.With controlling insufficiency of kidney-YANG, the sexual impotence cold womb caused by decline of the fire from the gate of life, waist and knee are cold Bitterly, normal and Radix Aconiti Lateralis Preparata mutual reinforcement between is use, RUGUI Annex VIII taste ball.If empty sun is floating more, heat in the upper and cold in the lower, dizziness conjunctival congestion, dyspnea due to deficiency sweating person, often with Fructus Corni, Fructus Schisandrae Chinensis are equal to use.3rd, the inclined promoting the circulation of blood of Chinese medicine cinnamon divides, and has the effect of promoting the flow of QI-blood by warming the meridian.With controlling the cold and deficiency of CHONG and REN meridians, closed dysmenorrhea, Often it is equal to Rhizoma Zingiberiss, Radix Rehmanniae Preparata use.If controlling flaccidity of the heart-yang, cold attacks punching, obstruction of qi in the chest and cardialgia person, is often equal to Radix Aconiti Lateralis Preparata, Rhizoma Zingiberiss use, with Warm heart-yang removes YIN-cold, the attached ball of RUGUI.Control carbuncle of yin nature and overflow swollen, bursts for a long time and does not holds back, and be often equal to the Radix Astragali, Radix Angelicae Sinensis use, with warming YANG and invigorating blood, dissipate Cold logical stagnant, such as YANGHE TANG.
Succinum: class of calming the nerves Chinese medicine, nature and flavor: sweet, put down;Return through: GUIXIN, liver, bladder warp;Effect: tranquillizing the mind by relieving convulsion, promoting blood circulationization The stasis of blood, relieving stranguria by diuresis;Cure mainly: for infantile convulsion epilepsy, amenorrhea abdominal mass, postpartum stagnation, stranguria with blood, stranguria caused by urinary stone.Chinese medicine succinum acts on: 1, loose Action of muscles;2nd, suppress central action.Chinese medicine succinum enters heart channel, is longer than tranquillizing the mind by relieving convulsion, therefore is adapted to uneasy all cards in terror.With controlling Infantile convulsion is twitched, and the normal and medicine such as Cinnabaris, Arisaema Cum Bile is ball, such as amber dragon-embracing ball.Control palpitation with fear, insomnia, how with Cinnabaris, Radix Polygalae etc. Compatibility is applied.Control infantile convulsion epilepsy, can be equal to Scorpio, Arisaema Cum Bile use.Chinese medicine succinum has promoting blood circulation to remove blood stasis, the work(of the removing blood stasis with potent drugs that stimulates the menstrual flow, and controls Abdominal mass, after-pains in puerperal, the normal and compatibility such as Carapax Trionycis, Rhizoma Sparganii, such as succinum dissipate.Control blood stasis is through closing, the normal and compatibility such as Semen Persicae, Radix Et Rhizoma Rhei. Chinese medicine succinum enters bladder warp, has the effect of inducing diuresis for treating stranguria syndrome, because this product has dissipate stasis of blood hemostasis to act on again, is particularly suited for stranguria with blood, alone is End clothes are effectively.With controlling stranguria caused by urinary stone, pyretic stranguria, can be with the relieving stranguria by diuresis medicine such as Spora Lygodii, Herba Lysimachiae with use.
Fructus Corni: astringentses Chinese medicine, nature and flavor: acid, tepor;Return through: return liver and kidney channel;Effect: liver and kidney tonifying, convergence is astringent or styptic treatment for spontaneous sweating; Cure mainly: it is used for having a dizzy spell, soreness of the waist and knees, metrorrhagia, leukorrhagia, menorrhagia, seminal emission, the enuresis, big apogee sweating, weak body and prostration.In Medicine Fructus Corni acts on: 1, adjusts immunologic function;2nd, antiinflammatory action;3rd, resisting pathogenic microbes effect;4th, suppress platelet aggregation;5、 Antishock function.Chinese medicine Fructus Corni liver and kidney tonifying, can mend essence, again can be supporing yang.For the soreness of the waist and knees caused by caused by liver and kidney deficiency, head Swoon dizzy etc., how to be equal to use with Radix Rehmanniae Preparata, Rhizoma Dioscoreae, such as LIUWEI DIHUANG WAN.Chinese medicine Fructus Corni can invigorating the liver and kidney, again can astringing to arrest bleeding Leukorrhagia stopping.For deficiency of both the liver and kidney, the metrorrhagia caused by the debility of CHONG and REN meridians, leukorrhagia, menorrhagia, often it is equal to Os Sepiae, charred Petiolus Trachycarpi use, such as Guchong Tang.Chinese medicine Fructus Corni can the kidney invigorating, can restrain astringent or styptic treatment for spontaneous sweating again.For the seminal emission of deficiency of kidney-YIN, it is equal to Radix Rehmanniae Preparata, Cortex Phellodendri With;As ZHIBAI DIHUANG WAN.As belonged to seminal emission caused by insufficiency of kidney-YANG, sexual impotence, then with Fructus Psoraleae, Radix Angelicae Sinensis with using, such as grass also pellet.For Control the enuresis, frequent micturition, with Ootheca Mantidiss, Fructus Rubi with use.Chinese medicine Fructus Corni can be used for big apogee sweating, the card of weak body and prostration, Chang Yuren Ginseng, Radix Aconiti Lateralis Preparata are equal to use.
Radix Rehmanniae Preparata, class of enriching blood Chinese medicine, nature and flavor: sweet, tepor;Return through: return liver and kidney channel;Effect: nourishing the blood and yin, vital essence replenishing and marrow benifiting; Cure mainly: for blood deficiency and yellow complexion, dizziness palpitaition, menoxenia, hectic fever night sweat, quench one's thirst, soreness of waist tinnitus.Chinese medicine Radix Rehmanniae Preparata acts on: 1, Strengthen immunologic function;2nd, hypoglycemic activity;3rd, hypotensive effect;4th, antiinflammatory action;5th, sedation;6th, antitumor action.Chinese medicine Radix Rehmanniae Preparata can nourishing the blood and yin, again can vital essence replenishing and marrow benifiting.For deficiency of the liver and kindey, soreness of the waist and knees caused by blood and essence asthenia, dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, normal and Radix Polygoni Multiflori Preparata, Semen Cuscutae is equal to use.The sweet temperature of Chinese medicine Radix Rehmanniae Preparata moistens enter liver, is longer than and enriches blood.With In blood deficiency and yellow complexion, dizziness, cardiopalmus, insomnia, menoxenia, metrorrhagia etc., normal and Radix Angelicae Sinensis, the Radix Paeoniae Alba are with use.As for blood deficiency and the deficiency of vital energy Person, with Radix Codonopsis, the Radix Astragali with use.Chinese medicine Radix Rehmanniae Preparata is longer than YIN nourishing.The hectic fever night sweat that causes for deficiency of kidney yin, seminal emission, Chang Yushan Medicine, Fructus Corni are equal to use.As the mild quenched one's thirst for the deficiency of YIN, can single heavy dose take orally effectively;As belonged to serious symptom, with Radix Adenophorae (Radix Glehniae), stone The adapteds such as dry measure used in former times;As belonged to quenching one's thirst of QIYINLIANGXU, when with the adapteds such as Radix Panacis Quinquefolii, the Radix Astragali.
Rhizoma Alismatis: diuresis detumescent class Chinese medicine, nature and flavor are sweet, light, tremble with fear;Return through: return kidney, bladder warp;Effect: promoting diuresis to eliminate damp pathogen, expel the heat-evil; Cure mainly: for dysuria, edema, have loose bowels, stranguria with turbid discharge, leukorrhagia.Chinese medicine Rhizoma Alismatis act on: 1, effect for reducing blood fat;2nd, hypoglycemic activity; 3rd, hypotensive effect;4th, antiinflammatory action;5th, the liver protecting effect;6th, diuresis;7th, immunosuppressant function.Chinese medicine Rhizoma Alismatis are sweet light Ooze and let out, the effect of its promoting diuresis to eliminate damp pathogen is similar to Poria, is commonly used by retention of water-damp in the body.The heat of kidney and bladder because it is cold in nature, can be let out, under Burnt damp and hot person is particularly suitable.With controlling dysuria, edema etc. is demonstrate,proved, often and the medicine adapted such as Poria, Polyporus, with strengthen promoting diuresis to eliminate damp pathogen it Work(.Control have loose bowels or phlegm retention caused by dizziness, can be with Rhizoma Atractylodis Macrocephalae compatibility, such as ZEXIE TANG.
According to " yi and Kui are derived from the same origin ", " Liver and kidney is same to be controlled ", it originates from "Nei Jing" to the present invention.Phase in the dirty traveling in meridians of Liver and kidney two Connection communicates, water wood interpromoting relation in five elements in five elements' association, in terms of function activity again with subordinate burnt, post mutually fire, essence and blood alternate, the moon altogether Sun mutually Ji etc., so, on pathology, then easily mutual Ji is mutually damaged, and declines with Sheng is same." homology " determines " with disease ", therefore, root of the present invention Card according to " yi and Kui are derived from the same origin, Liver and kidney is same to be controlled " controls rule.Advocate " kind YANG invigorating person, must treating YANG within YIN, then positive cloudy help, biochemical infinite; Kind nourishing YIN person, must treating YIN within YANG, then cloudy positive help, and fountainhead is inexhaustible." negative and positive of Liver and kidney start with, the negative and positive of conditioning patient, gas Blood, function, coordinate steady mechanism in body, reach the purpose of " YIN and YANG in a relative equilibrium "." deficiency syndrome should be treated by tonifying method " is that treatment deficiency syndrome are big Method, but tonic is with proper, also many gas stop up, greasy diaphragm, counter make transporting and transforming function of the spleen and stomach dull, cause gastral cavity swollen indigestion and loss of appetite, cause to change disease.To length Phase confirmed fatigue, weakness due to chronic disease, the mental overdraw of muscle power or the headache that causes of old deficiency of both the liver and kidney. dizziness and blurred vision, brothers' heart send out cold, Heating insomnia and dreamful sleep, seminal emission sexual impotence, premature ejaculation hyposexuality, alopecia aversion to cold and cold limbs;Soreness of the waist and knees fatiguability, lassitude, prostate Increase wound, prostatitis, neurasthenia, tinnitus is forgetful, cardiopalmus The book of Changes, visual deterioration evident in efficacy, physical resource is as follows:
The clinical test of pesticide effectiveness
1st, clinical data
1.1 patient data
100 insufficiency of kidney-YANG patients for the treatment of group, are male, 15-55 year, 100 insufficiency of kidney-YANG patients of matched group, are male, 15- 55 years old.
1.2 diagnostic criteria
" new Chinese medicine treats the guideline of clinical investigations of insufficiency of kidney-YANG " promulgated with reference to Ministry of Public Health is diagnostic criteria, primary symptom: waist Knee joint soreness, aversion to cold and cold limbs, hyposexuality, body of the tongue is fat big, and tongue is white, deep pulse;Secondary disease: lassitude, nocturia, edema of lower limbs, Shortness of breath and breathe heavily, big loose stool, alopecia.
Curative effect determinate standard:
Clinical recovery: the symptom of insufficiency of kidney-YANG, sign disappears;
Effective: the symptom of insufficiency of kidney-YANG, sign are obviously improved;
Effective: the symptom of insufficiency of kidney-YANG, sign all take a favorable turn;
Invalid: the symptom of insufficiency of kidney-YANG, sign is no improved.
2nd, Therapeutic Method
Treatment group uses Chinese herbs paste of the present invention, and daily 2-3 time, a patch, is attached to waist 30-50 minute every time;Matched group is administered orally JISHENG SHENQI WAN, every ball 9g, daily 2-3 time, 1 ball every time.With 1 Zhou Weiyi course for the treatment of, respectively used with treatment group and matched group Four course for the treatment of effect contrasts.
3rd, clinical test results are shown in Table 1.
Table 1. clinical test results
Group Number of cases Recovery from illness Effective Effectively Invalid Cure rate (%) Total effective rate (%)
Treatment group 100 73 20 4 4 73 96
Matched group 100 60 12 3 15 60 85
The individual difference of all patients of this test and Selection is negligible, by the curative effect ratio of matched group in upper table and treatment group Relatively, show that Chinese herbs paste curative effect of the present invention is better than conventional treatments.
Model case
Zhao so-and-so, man, 42 years old, people from Zhengzhou City Henan Province, patient's soreness of the waist and knees, aversion to cold and cold limbs, nocturia, libido reduce.Examine Break and be: insufficiency of kidney-YANG.Using the embodiment of the present invention 1 gained Chinese herbs paste, 3 times a day, every time a patch, a patch 30 minutes, is treated with 2 Journey, symptom, sign mitigate, and continuation is wholly absent with 2 courses for the treatment of, symptom, sign, cure, and follow-up half a year does not recur.
Korea Spro, man, 33 years old, people from Nanyang City, Henan Province, patient's soreness of the waist and knees and pain, sexual impotence, cold sperm, stool chronic diarrhea is more than, Clear urine in large amounts or frequent urination at night, the fat white, slippery and moist fur of light red tongue, deep-slow pulse, it is diagnosed as: insufficiency of kidney-YANG.Using the embodiment of the present invention 2 gained Chinese medicine Patch, 3 times a day, every time 1 patch, a patch 50 minutes, with 3 courses for the treatment of, the soreness of waist, cold extremities symptom mitigation, continues with 2 courses for the treatment of, disease Shape, sign are wholly absent, and cure, and follow-up half a year does not recur.
Finally illustrate, above example only in order to technical scheme is described and unrestricted, art technology Equivalent or equivalent modifications and replacement that personnel are done to technical scheme, belong to protection scope of the present invention.

Claims (4)

1. a kind of Chinese herbs paste treating insufficiency of kidney-YANG is it is characterised in that by following weight meter: Herba Cynomorii 5~9g, and Herba Epimedii 3~ 9g, Radix Morindae Officinaliss 10-15g, Cortex Cinnamomi 2-5g, succinum 1~2g, Fructus Corni 6~12g, Radix Rehmanniae Preparata 10-30g and Rhizoma Alismatis 6-9 g make raw material Medicine is made;During preparation, above-mentioned raw materials medicament mixed is rinsed 20-50 minute with the vinegar of 2.5-6.8wt%, reused 30- 40 DEG C of deionized water rinsing 3-10 minute, drains, and puts into drier 15-30 minute, and baking temperature is 55-65 DEG C, grinds Wear into the fine powder of 20-50 mesh, the concentration being subsequently adding fine powder 5 times amount is the ethanol of 32-47wt%, is flowed back at 85-90 DEG C 30-50 minute, collects backflow, filters, and obtains filtrate, and heating concentration and recovery ethanol obtains extractum;It is 1.48- that extractum is condensed into density The thick paste of 1.58g/ml, thick paste cooling after spread out even in medicated plaster cloth, obtain final product.
2. the Chinese herbs paste for the treatment of insufficiency of kidney-YANG according to claim 1 is it is characterised in that by following weight meter: Herba Cynomorii 9g, Herba Epimedii 3g, Radix Morindae Officinaliss 10g, Cortex Cinnamomi 2g, succinum 2 g, Fructus Corni 6g, Radix Rehmanniae Preparata 10g and Rhizoma Alismatis 9g make material medicine system Become;During preparation, above-mentioned raw materials medicament mixed is rinsed 20 minutes with the vinegar of 2.5wt%, reuse 30 DEG C of deionized water punching Wash 3 minutes, drain, put into drier 15 minutes, baking temperature is 55 DEG C, grinds to form the fine powder of 20 mesh, be subsequently adding thin The concentration of powder 5 times amount is the ethanol of 32wt%, carries out flowing back 30 minutes at 85 DEG C, collects backflow, filters, obtains filtrate, heating Concentration and recovery ethanol obtains extractum;Extractum be condensed into density be 1.48g/ml thick paste, thick paste cooling after spread out even in medicated plaster cloth, that is, ?.
3. the Chinese herbs paste for the treatment of insufficiency of kidney-YANG according to claim 1 is it is characterised in that by following weight meter: Herba Cynomorii 7g, Herba Epimedii 6g, Radix Morindae Officinaliss 13g, Cortex Cinnamomi 4g, succinum 1.5g, Fructus Corni 8g, Radix Rehmanniae Preparata 20g and Rhizoma Alismatis 8g make material medicine system Become;During preparation, above-mentioned raw materials medicament mixed is rinsed 50 minutes with the vinegar of 6 .8wt%, reused 40 DEG C of deionized water Rinse 10 minutes, drain, put into drier 30 minutes, baking temperature is 65 DEG C, then it is thin to grind to form 50 purposes with grinder Powder, the concentration being subsequently adding fine powder 5 times amount is the ethanol of 47wt%, carries out flowing back 50 minutes at 90 DEG C, collects backflow, mistake Filter, obtains filtrate, and heating concentration and recovery ethanol obtains extractum;Extractum is condensed into the thick paste that density is 1.58g/ml, spreads out after thick paste cooling Even in medicated plaster cloth, obtain final product.
4. the Chinese herbs paste for the treatment of insufficiency of kidney-YANG according to claim 1 is it is characterised in that by following weight meter: Herba Cynomorii 5g, Herba Epimedii 9g, Radix Morindae Officinaliss 15g, Cortex Cinnamomi 5g, succinum 1g, Fructus Corni 12g, Radix Rehmanniae Preparata 30g and Rhizoma Alismatis 6g make material medicine system Become;During preparation, above-mentioned raw materials medicament mixed is rinsed 35 minutes with the vinegar of 3wt%, reused 35 DEG C of deionized water rinsing 5 minutes, drain, put into drier 22 minutes, baking temperature is 60 DEG C, then grind to form the fine powder of 40 mesh with grinder, so Add the ethanol for 40wt% for the concentration of fine powder 5 times amount afterwards, carry out flowing back 40 minutes at 88 DEG C, collect backflow, filter, obtain filter Liquid, heating concentration and recovery ethanol obtains extractum;Extractum be condensed into density be 1.50g/ml thick paste, thick paste cooling after spread out even in plaster On cloth, obtain final product.
CN201611081493.1A 2016-11-30 2016-11-30 Traditional Chinese medicine patch for treating deficiency of kidney-yang Withdrawn CN106361918A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288953A (en) * 2018-11-27 2019-02-01 河南羚锐制药股份有限公司 A kind of Chinese herbs paste tonified the kidney and support yang
CN112043811A (en) * 2020-09-08 2020-12-08 国珍健康科技(北京)有限公司 Radix morindae officinalis and radix gastrodiae patch and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049401A (en) * 2007-05-16 2007-10-10 北京艺信堂医药研究所 Composition of Chinese traditional medicine for treating barrenness caused by lack of sperm

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049401A (en) * 2007-05-16 2007-10-10 北京艺信堂医药研究所 Composition of Chinese traditional medicine for treating barrenness caused by lack of sperm

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288953A (en) * 2018-11-27 2019-02-01 河南羚锐制药股份有限公司 A kind of Chinese herbs paste tonified the kidney and support yang
CN112043811A (en) * 2020-09-08 2020-12-08 国珍健康科技(北京)有限公司 Radix morindae officinalis and radix gastrodiae patch and preparation method thereof

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Application publication date: 20170201