CN104530014B - 2‑氧代‑1,2‑二氢苯并[cd]吲哚‑6‑磺酰胺类化合物及其组合物和应用 - Google Patents

2‑氧代‑1,2‑二氢苯并[cd]吲哚‑6‑磺酰胺类化合物及其组合物和应用 Download PDF

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CN104530014B
CN104530014B CN201410821535.5A CN201410821535A CN104530014B CN 104530014 B CN104530014 B CN 104530014B CN 201410821535 A CN201410821535 A CN 201410821535A CN 104530014 B CN104530014 B CN 104530014B
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indoles
oxo
ethyl
dihydrobenzos
sulfonamide
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CN104530014A (zh
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许�永
薛晓纤
张岩
李静
金翔宇
罗小雨
宋宇
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Guangzhou Institute of Biomedicine and Health of CAS
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    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/42Oxazoles
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/53751,4-Oxazines, e.g. morpholine
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CN201410821535.5A 2013-12-25 2014-12-24 2‑氧代‑1,2‑二氢苯并[cd]吲哚‑6‑磺酰胺类化合物及其组合物和应用 Active CN104530014B (zh)

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Publication number Priority date Publication date Assignee Title
CN111662226B (zh) * 2015-01-28 2022-03-18 中国科学院广州生物医药与健康研究院 一种2-氧代-1,2-二氢苯并[cd]吲哚类化合物
CN107614062A (zh) 2015-03-12 2018-01-19 加利福尼亚大学董事会 用RORγ抑制剂治疗癌症的方法
CN114790169A (zh) * 2016-01-29 2022-07-26 中国科学院广州生物医药与健康研究院 四氢喹啉相关二环类化合物及其应用
WO2021047406A1 (fr) * 2019-09-10 2021-03-18 四川科伦博泰生物医药股份有限公司 Composé tricyclique, composition pharmaceutique le contenant, procédé de préparation correspondant et utilisation associée
CN113912563A (zh) * 2020-07-10 2022-01-11 中国科学院广州生物医药与健康研究院 一种苯并五元氮杂环化合物及其应用
CN111995563A (zh) * 2020-08-04 2020-11-27 常州大学 磷酸二酯酶pde2活性抑制剂

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DE2606716A1 (de) * 1975-02-21 1976-09-02 Ciba Geigy Ag Neue dispersionsfarbstoffe
CN1863785A (zh) * 2003-08-08 2006-11-15 沃泰克斯药物股份有限公司 在疼痛的治疗中用作钠或钙通道阻断剂的杂芳基氨基磺酰基苯基衍生物
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Identification and Characterization of Novel Inhibitors of mPTPB, an Essential Virulent Phosphatase from Mycobacterium tuberculosis;Lan Chen et al.;《Medicinal Chemistry Letters》;20100707;第7卷(第1期);355-359 *
Identification of Novel Compounds That Increase SMN Protein Levels Using an Improved SMN2 Reporter Cell Assay;Jonathan J. Cherrry et al.;《Journal of Biomolecular Screening》;20120430;第17卷(第4期);481-495 *
Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase;Arindam Talukdar et al.;《Bioorganic & Medicinal Chemistry》;20100408;第18卷(第10期);3518-3534 *

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