CN104524445A - Wind-expelling and convulsion-relieving traditional Chinese medicine for treating twitching of eyelid and preparation method thereof - Google Patents
Wind-expelling and convulsion-relieving traditional Chinese medicine for treating twitching of eyelid and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a wind-expelling and convulsion-relieving traditional Chinese medicine for treating twitching of eyelid. The traditional Chinese medicine is mainly prepared from the following medicinal raw materials in parts by weight: 10-20 parts of astragalus membranaceus, 6-9 parts of raspberry, 10-15 parts of ligusticum wallichii, 10-18 parts of junci medulla, 6-9 parts of safflower carthamus, 4-9 parts of poria cocos, 8-15 parts of codonopsis pilosula, 4-8 parts of licorice root, 6-15 parts of cynanchum paniculatum, 8-12 parts of goat horn, 9-16 parts of cinnamon, 8-12 parts of radix aconite lateralis preparata, 6-9 parts of radix curcumae and 8-12 parts of malt. The traditional Chinese medicine has the advantages of remarkable effect, quick response and high cure rate.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to " eyelid flickering " and to expelling wind and relieving convulsion Chinese medicine and preparation method.
Background technology
Eyelid twitch refers to that upper eye lid or lower eyelid can not move by automatic control ground Chu Ti Shun, is commonly called as eyelid flickering or tie of the orbicular muscie.Its clinical manifestation is that upper eye lid or lower eyelid are beated, time dredge time-frequency, can not automatic control.General overwork, watching for a long time, when not having enough sleep, then beat more frequent, after rest, symptom can alleviate or disappear.If when born of the same parents' eyelid is beated, together with all tired dynamic person of half side facial muscle and eyebrow, bicker, with the passing of time do not heal, probably have fish sticking its mouth out of the water inclined change.Primary disease is many, and because of deficiency of both QI and blood or prolonged illness imbalance, labor is looked forward or upwards excessively, damage heart spleen, deficiency of both the heart and spleen, and muscles loses supports and moves.Becoming has because of liver spleen blood deficiency, with the passing of time raw wind, stirring-up of pathogenic wind in the interior resulting from deficiency, leads and drags born of the same parents' eyelid and tramp.Primary disease is fallen ill in born of the same parents' eyelid, in close relations with conscience spleen.Dialectical based on deficiency syndrome.Born of the same parents' eyelid tramp, fatigue increases the weight of, vexed insomnia, and lack of appetite Mental fatigue person is heart spleen blood deficiency.Twitching of the eyelid without stopping can not automatic control person be wind syndrome due to blood-deficiency.
Publication No. CN 103301286 A(application number 201310247489.8) Chinese patent literature disclose and a kind ofly treat that eye is puckery, the medicine of twitching of the eyelid; With Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Fructus Lycii, Flos Chrysanthemi, Fructus Viticis, Rhizoma Dioscoreae, Fructus Rubi, clam worm, Rhizoma Dioscoreae, Cortex Moutan, Rhizoma Alismatis, Radix Stephaniae Tetrandrae, Scorpio for raw material, put into after above-mentioned raw materials medicine is cleaned up in decoction vessel, add water 500 milliliters, decoct 30 minutes, drain medicine soup; Add water again and decoct again, connect three times, finally three medicinal liquids are mixed and made into decoction.Publication No. CN 102940745 A(application number 201210510676.6) Chinese patent literature disclose a kind of pill being used for the treatment of blepharospasm, belong to the field of Chinese medicines.The raw material composition of pill of the present invention and parts by weight are: 90 ~ 120 parts, Radix Glycyrrhizae, Radix Polygalae 60 ~ 90 parts, Radix Astragali Preparata 50 ~ 70 parts, Cortex Cinnamomi 50 ~ 65 parts, the Rhizoma Atractylodis Macrocephalae 45 ~ 60 parts, Rhizoma Atractylodis 40 ~ 60 parts, Radix Morindae Officinalis 40 ~ 55 parts, Rhizoma Cimicifugae 35 ~ 50 parts, Rhizoma Chuanxiong 30 ~ 45 parts, Herba Asari 30 ~ 40 parts, Fructus Rosae Laevigatae 25 ~ 35 parts, Arisaema Cum Bile 20 ~ 30 parts, Radix Angelicae Sinensis 15 ~ 25 parts, Poria cum Radix Pini 10 ~ 20 parts, Faeces bombycis 5 ~ 15 parts, Rhizoma Curculiginis 5 ~ 10 parts.
The treatment means that modern Western medicine is conventional, be mainly modus operandi, its risk is larger, recover slow, and somewhat expensive, therefore often use tcm therapy, traditional therapy is mainly by acupuncture or decoction, and therapeutic effect is not very desirable, so need a kind of new Be very effective ground of research Chinese medicine formula.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take safe and applicable wide " eyelid flickering " and to expelling wind and relieving convulsion Chinese medicine.
Technical scheme of the present invention is:
" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from, is weight portion: Radix Astragali 10-20 primarily of following bulk drugs; Fructus Rubi 6-9; Rhizoma Chuanxiong 10-15; Medulla Junci 10-18; Flos Carthami 6-9; Poria 4-9; Radix Codonopsis 8-15; Radix Glycyrrhizae 4-8; Radix Cynanchi Paniculati 6-15; Cornu Caprae seu Ovis 8-12; Cortex Cinnamomi 9-16; Radix Aconiti Lateralis Preparata 8-12; Radix Curcumae 6-9; Fructus Hordei Germinatus 8-12.
Preferably: Radix Astragali 12-18; Fructus Rubi 7-8; Rhizoma Chuanxiong 11-14; Medulla Junci 12-16; Flos Carthami 7-8; Poria 5-8; Radix Codonopsis 10-13; Radix Glycyrrhizae 5-7; Radix Cynanchi Paniculati 8-13; Cornu Caprae seu Ovis 9-11; Cortex Cinnamomi 11-14; Radix Aconiti Lateralis Preparata 9-11; Radix Curcumae 7-8; Fructus Hordei Germinatus 9-11.
More preferably: the Radix Astragali 15; Fructus Rubi 7.5; Rhizoma Chuanxiong 12.5; Medulla Junci 14; Flos Carthami 7.5; Poria 6.5; Radix Codonopsis 11.5; Radix Glycyrrhizae 6; Radix Cynanchi Paniculati 10.5; Cornu Caprae seu Ovis 10; Cortex Cinnamomi 12.5; Radix Aconiti Lateralis Preparata 10; Radix Curcumae 7.5; Fructus Hordei Germinatus 10.
Described " eyelid flickering " expellings wind and relieving convulsion Chinese medicine, and be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 30-50 minute (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves, mix with step (4) filtrate, sterilizing encapsulates to obtain decoction.
Described " eyelid flickering " expellings wind and relieving convulsion the preparation method of Chinese medicine decoction, be placed in step (1) in soup soak 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes).
Described " eyelid flickering " Chinese medicine of expellingging wind and relieving convulsion, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, be ground into end altogether with step (1) (2) (3) gained medical material, sieve and be packaged into powder.
Described " eyelid flickering " to be expellingged wind and relieving convulsion the preparation method of Chinese powder medicine, is crossed 150-180 mesh sieve (preferred: to cross 160-170 mesh sieve in step (4); Be more preferably: cross 165 mesh sieves).
Described " eyelid flickering " expellings wind and relieving convulsion Chinese medicine, and be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, and be ground into end altogether with step (1) (2) (3) gained medical material and cross 160 mesh sieves, be filled in Capsules, make capsule.
Described " eyelid flickering " expellings wind and relieving convulsion the preparation method of Chinese medicine capsules, and step becomes capsule according to the metric system of 0.3g/ grain in (4).
Described " eyelid flickering " expellings wind and relieving convulsion Chinese medicine, and be made into pharmaceutically acceptable thick paste, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak 25 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 30-50 minute (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) concentration step (4) gained filtrate is to clear paste, stirs after step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves with clear paste, and cooling encapsulates to obtain thick paste.
Described " eyelid flickering " expellings wind and relieving convulsion the preparation method of traditional Chinese medicine thick paste, and the relative density of step (5) clear paste is 1.21-1.23(70 DEG C) (preferred: relative density is 1.22(70 DEG C)).
" eyelid flickering " provided by the invention expellings wind and relieving convulsion Chinese medicine formula science, and preparation method is simple.In addition, its excellent part also shows:
1, the medical material selected by the present invention, is and has no side effect, and can use by safety clothes;
2, resulting dosage forms taking convenience, efficacy stability, clinical cure rate is high;
3, the present invention is directed to " eyelid flickering " symptom, have supplementing QI for promoting the production of body fluid, effect of invigorating blood circulation of enriching blood.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Radix Astragali: property is sweet, tepor.Return lung, spleen, liver, kidney channel.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be generally used for the treatment deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Fructus Rubi: base is former: for the dry fruit of basin is covered in Rosaceae rubus East China
.nature and flavor with return through: sweet, sour, temperature.Return liver, kidney, urinary bladder channel.Function with cure mainly: supplementing the kidney to control the nocturnal reducing urination, nourishing the liver to improve visual acuity.For emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, order is secretly dim-sighted.
Rhizoma Chuanxiong: nature and flavor with return through: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: activating QI to alleviate the depression, and method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Medulla Junci: base is former: be the dry stem pith of rush family plant Medulla Junci.Nature and flavor with return through: sweet, light, be slightly cold.GUIXIN, lung, small intestine meridian.There is clearing away heart-fire, effect of diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.
Flos Carthami: nature and flavor with return through: pungent, temperature.GUIXIN, Liver Channel.Function with cure mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, addiction abdominal mass mass in the abdomen, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, injury from falling down, skin infection swells and ache.
Poria: nature and flavor with return through: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Codonopsis: nature and flavor with return through: sweet, flat.Return spleen, lung meridian.Function with cure mainly: spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Radix Glycyrrhizae: sweet in the mouth, property is put down.There is QI invigorating invigorating middle warmer, relieving spasm to stop pain, effect of eliminating fire and detoxication, for the disease of laryngopharynx swelling and pain.
Radix Cynanchi Paniculati: base is former: be the dry root welding technology of Luo Mo section plant Radix Cynanchi Paniculati.Nature and flavor with return through: pungent, temperature.Return liver, stomach warp.Function with cure mainly: dispel the wind, removing dampness, pain relieving, antipruritic.For rheumatic arthralgia, stomachache distension, toothache, lumbago, falls and flutters the pain of injury, rubella, eczema.
Cornu Caprae seu Ovis: base is former: be the angle of bovid male goat or male sheep.Nature and flavor: salty are cool.Gui Jing: enter liver, heart channel.Function cures mainly: heat clearing away, relieving convulsion, improving eyesight, removing toxic substances.Control pediatric epilepsy scared, headache due to pathogenic wind-heat, unhappy, spit blood, optic atrohic blindness, toxic swelling.
Cortex Cinnamomi: base is former: be dried bark and the branch skin of canella Cortex Cinnamomi.Chemical analysis: skin is containing volatile oil (title Oleum Cinnamomi) 1 ~ 2%, and main component is cinnamic aldehyde 75 ~ 90%, and containing a small amount of acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester, phenylpropyl acetate etc.This product is not containing eugenol.Still mucous, tannin etc.Nature and flavor: Xin Gan, heat.Gui Jing: enter kidney, spleen, urinary bladder channel.Function cures mainly: complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.
Radix Aconiti Lateralis Preparata: base is former: be the other raw tuber (daughter root) of ranunculaceae plant Aconitum carmichjaelii Debx. (cultivation product).Nature and flavor: Xin Gan, heat, poisonous.Gui Jing: enter the heart, spleen, kidney channel.Function cures mainly: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispelling cold and removing dampness.Control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted inverse, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema children's intermittent infantile convulsion, anemofrigid-damp arthralgia, the contracture of Wei lame, sexual impotence, and cold womb is cloudy, the disease of the leakage of cellulitis skin ulcer and all chronic diseaseses.
Radix Curcumae: base is former: be the tuber of zingiberaceous plant Rhizoma Curcumae Longae, Radix Curcumae or Rhizoma Curcumae.Property pungent, bitter, cold.Return liver, the heart, lung meridian.Can regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be generally used for amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Fructus Hordei Germinatus (Fructus Hordei Germinatus) nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Effect: spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Cure mainly: do not disappear for food stagnation, women's ablactation, Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.Do not disappear for food stagnation, abdominal distention.
embodiment 1" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from: Radix Astragali 10g, Fructus Rubi 6g, Rhizoma Chuanxiong 10g, Medulla Junci 10g, Flos Carthami 6g, Poria 4g, Radix Codonopsis 8g, Radix Glycyrrhizae 4g, Radix Cynanchi Paniculati 6g ， Cornu Caprae seu Ovis 8g, Cortex Cinnamomi 9g, Radix Aconiti Lateralis Preparata 8g, Radix Curcumae 6g, Fructus Hordei Germinatus 8g primarily of following bulk drugs.Above-mentioned " eyelid flickering " expelling wind and relieving convulsion preparation method of Chinese medicine decoction is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak 20 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, be rolled into cake, be placed in parch container, add rice wine and mix thoroughly, slow fire stir-fries 5 minutes, takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 30 minutes, take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves, mix with step (4) filtrate, sterilizing encapsulates to obtain decoction.
embodiment 2" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from: Radix Astragali 20g, Fructus Rubi 9g, Rhizoma Chuanxiong 15g, Medulla Junci 18g primarily of following bulk drugs, Flos Carthami 9g, Poria 9g, Radix Codonopsis 15g, Radix Glycyrrhizae 8g, Radix Cynanchi Paniculati 15g Cornu Caprae seu Ovis 12g, Cortex Cinnamomi 16g, Radix Aconiti Lateralis Preparata 12g, Radix Curcumae 9g, Fructus Hordei Germinatus 12g.Above-mentioned " eyelid flickering " expelling wind and relieving convulsion preparation method of Chinese powder medicine is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, be rolled into cake, be placed in parch container, add rice wine and mix thoroughly, slow fire stir-fries 8 minutes, takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, be ground into end altogether with step (1) (2) (3) gained medical material, and cross 165 mesh sieves and be packaged into powder.
Model case: xxx, male, 36 years old.That felt suddenly before half a year that the right eye skin of oneself can't help beats, but be not present to the mind, eyelid flickering constantly increases the weight of subsequently, even starts to occur that right face is twitched repeatedly, a little medicine that gone local hospital to take, effect is not had after taking medicine, symptom is but more and more obvious, and twitch more and more frequent, the intermittent time is shorter and shorter, arrive large hospital inspection afterwards, be diagnosed as eyelid twitch.
Taking this example gained Chinese powder medicine, each 4g, warm boiled water, one day twice, five days is a course for the treatment of.After taking three days, the twitch number of times of patient declines to some extent, and symptom alleviates a little, after continuing two courses for the treatment of of use, substantially can control saccade, and uncomfortable disease is eliminated, and does not affect normal life.
embodiment 3" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from: Radix Astragali 12g, Fructus Rubi 7g, Rhizoma Chuanxiong 11g, Medulla Junci 12g primarily of following bulk drugs, Flos Carthami 7g, Poria 5g, Radix Codonopsis 10g, Radix Glycyrrhizae 5g, Radix Cynanchi Paniculati 8g Cornu Caprae seu Ovis 9g, Cortex Cinnamomi 11g, Radix Aconiti Lateralis Preparata 9g, Radix Curcumae 7g, Fructus Hordei Germinatus 9g.Above-mentioned " eyelid flickering " expelling wind and relieving convulsion preparation method of Chinese medicine capsules is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, be rolled into cake, be placed in parch container, add rice wine and mix thoroughly, slow fire stir-fries 8 minutes, takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, and be ground into end altogether with step (1) (2) (3) gained medical material and cross 160 mesh sieves, be filled in Capsules, become capsule according to the metric system of 0.3g/ grain.
Model case: xxx, women, 24 years old.Patient's readme is life-time service computer gang, regular object for appreciation computer of staying up late, over nearest one month, eyelid starts to beat, think it is that rest is bad, just how not take notice of, rear symptom is serious gradually, and jumping frequency rate is more and more faster, face has spasm phenomenon, eat a little medicine can not alleviate, then arrived examination in hospital, be diagnosed as eyelid and beat.
Doctor advised is performed the operation, and patient does not think that cost is too large, recommends to take this example gained capsule through people.Taken three times a day, one time four, within five days, be a course for the treatment of.After taking a course for the treatment of, eyelid flickering transference cure, after taking two courses for the treatment of continuously, spasm symptom alleviates, and consolidates a course for the treatment of, recovery from illness.
embodiment 4" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from: Radix Astragali 18g, Fructus Rubi 8g, Rhizoma Chuanxiong 14g, Medulla Junci 16g primarily of following bulk drugs, Flos Carthami 8g, Poria 8g, Radix Codonopsis 13g, Radix Glycyrrhizae 7g, Radix Cynanchi Paniculati 13g Cornu Caprae seu Ovis 11g, Cortex Cinnamomi 14g, Radix Aconiti Lateralis Preparata 11g, Radix Curcumae 8g, Fructus Hordei Germinatus 11g.Above-mentioned " eyelid flickering " expelling wind and relieving convulsion preparation method of traditional Chinese medicine thick paste is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak 25 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, be rolled into cake, be placed in parch container, add rice wine and mix thoroughly, slow fire stir-fries 8 minutes, takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 40 minutes, take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) concentration step (4) gained filtrate to relative density is 1.22(70 DEG C) clear paste, stir with clear paste after step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves, cool, encapsulate to obtain thick paste.
Model case: xxx, male, 18 years old.Main suit: patient indulges in game, often stay up late and play games, there is the symptom of eyelid flickering two months ago, be not present to the mind, can over nearly one month, symptom increases the weight of gradually, beat and can not control, even there is spasm phenomenon in face, and household worries that brain goes wrong, take hospital to check, be diagnosed as saccade and facial spasm.
Agree to through household, patient carries out Minimally Invasive Surgery, and postsurgery symptoms is eased, but less than two months, disease relapse, under the recommendation of friend, takes this example gained traditional Chinese medicine thick paste, each 4g, warm boiled water, one day twice, within five days, be a course for the treatment of, period in a medicine patient normally work and rest, after the course for the treatment of, the state of an illness is stablized, and symptom alleviates, and takes three courses for the treatment of continuously, saccade and the facial spasm phenomenon of patient all disappear, and seldom recur, do not affect normal learning life completely.
embodiment 5" eyelid flickering " to be expellingged wind and relieving convulsion Chinese medicine, is prepared from: Radix Astragali 15g, Fructus Rubi 7.5g primarily of following bulk drugs, Rhizoma Chuanxiong 12.5g, Medulla Junci 14g, Flos Carthami 7.5g, Poria 6.5g, Radix Codonopsis 11.5g, Radix Glycyrrhizae 6g, Radix Cynanchi Paniculati 10.5g Cornu Caprae seu Ovis 10g, Cortex Cinnamomi 12.5g, Radix Aconiti Lateralis Preparata 10g, Radix Curcumae 7.5g, Fructus Hordei Germinatus 10g.Above-mentioned " eyelid flickering " expelling wind and relieving convulsion preparation method of Chinese medicine decoction is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak 25 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, be rolled into cake, be placed in parch container, add rice wine and mix thoroughly, slow fire stir-fries 8 minutes, takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 40 minutes, take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves, mix with step (4) filtrate, sterilizing encapsulates to obtain decoction.
test example 1embodiment 5 gained " eyelid flickering " is expellingged wind and relieving convulsion the clinical practice of Chinese medicine decoction:
Choose crowd: according to hospital outpatient case history, screening saccade patient 440 example, wherein women 218 example, male 222 example, the range of age 15-65 year, the mean age is 30.8 years old, the course of disease at 2 months in 3 years.
Before test, patient is divided into two groups at random, experimental group 318 example and matched group 122 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes embodiment 5 gained Chinese medicine decoction, each 40-80ml, warmly takes, sooner or later each once, within five days, be a course for the treatment of; Matched group takes other conventional medicines (GUIPI WAN, Radix Ginseng support battalion's ball, oryzanol or acupuncture etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: recovery from illness: eyelid is beated transference cure, the corners of the mouth is twitched and facial spasm transference cure; Effective: eyelid is beated remission, the corners of the mouth is twitched and facial spasm remission; Invalid: symptom is with treating front no significant difference.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, use in the experimental group of embodiment 5 products obtained therefrom, eyelid is beated transference cure, the patient that the corners of the mouth is twitched and facial spasm symptom is eliminated has 241 examples (75.8%), eyelid is beated minimizing, the patient that the corners of the mouth is twitched and facial spasm symptom alleviates has 73 examples (23.0%), and the total effective rate of known experimental group is 98.8%.The patient fully recovered in matched group has 81 examples (66.4%), and the effective patient that symptom is improved has 26(21.3%), the total effective rate of matched group is 87.7%.Experimental group product curative effect used is obviously better than matched group, and before and after treatment, patient mental's state of experimental group is significantly increased comparatively before.Follow up a case by regular visits in 1 year, without recurrence.
The Chinese medicine used in the present invention, the heat clearing away of the nourishing blood to promote the production of body fluid of convenient, the Radix Codonopsis of relieving inflammation or internal heat of the benefiting QI for strengthening the superficies of the Radix Astragali, the promoting blood circulation and stopping pain of Rhizoma Chuanxiong, Medulla Junci, the mind calming spleen invigorating of Poria, the QI invigorating invigorating middle warmer of Radix Glycyrrhizae, the wind-expelling pain-stopping, Cornu Caprae seu Ovis of Radix Cynanchi Paniculati is relieving convulsion, spleen is opened in the YANG invigorating warming the stomach of Cortex Cinnamomi, the benefit fire stomach invigorating that is supporing yang, Fructus Hordei Germinatus of Radix Aconiti Lateralis Preparata, for the disease of eyelid flickering, there is significant curative effect, all medicines share, can effectively alleviate uncomfortable disease, thus raising clinical cure rate, make total effective rate to reach 98.8%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. " eyelid flickering " expellings wind and relieving convulsion Chinese medicine, it is characterized in that, is prepared from primarily of following bulk drugs, be weight portion: Radix Astragali 10-20; Fructus Rubi 6-9; Rhizoma Chuanxiong 10-15; Medulla Junci 10-18; Flos Carthami 6-9; Poria 4-9; Radix Codonopsis 8-15; Radix Glycyrrhizae 4-8; Radix Cynanchi Paniculati 6-15; Cornu Caprae seu Ovis 8-12; Cortex Cinnamomi 9-16; Radix Aconiti Lateralis Preparata 8-12; Radix Curcumae 6-9; Fructus Hordei Germinatus 8-12.
2. as claimed in claim 1 " eyelid flickering " expellings wind and relieving convulsion Chinese medicine, it is characterized in that, Radix Astragali 12-18; Fructus Rubi 7-8; Rhizoma Chuanxiong 11-14; Medulla Junci 12-16; Flos Carthami 7-8; Poria 5-8; Radix Codonopsis 10-13; Radix Glycyrrhizae 5-7; Radix Cynanchi Paniculati 8-13; Cornu Caprae seu Ovis 9-11; Cortex Cinnamomi 11-14; Radix Aconiti Lateralis Preparata 9-11; Radix Curcumae 7-8; Fructus Hordei Germinatus 9-11(is preferably: the Radix Astragali 15; Fructus Rubi 7.5; Rhizoma Chuanxiong 12.5; Medulla Junci 14; Flos Carthami 7.5; Poria 6.5; Radix Codonopsis 11.5; Radix Glycyrrhizae 6; Radix Cynanchi Paniculati 10.5; Cornu Caprae seu Ovis 10; Cortex Cinnamomi 12.5; Radix Aconiti Lateralis Preparata 10; Radix Curcumae 7.5; Fructus Hordei Germinatus 10).
3. " eyelid flickering " as described in as arbitrary in claim 1-2 expellings wind and relieving convulsion Chinese medicine, and it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 30-50 minute (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves, mix with step (4) filtrate, sterilizing encapsulates to obtain decoction.
4. as claimed in claim 3 " eyelid flickering " expellings wind and relieving convulsion the preparation method of Chinese medicine decoction, it is characterized in that, be placed in step (1) in soup soak 20-30 minute (preferred: to soak 22-28 minute; Be more preferably: soak 25 minutes).
5. as described in as arbitrary in claim 1-2 " eyelid flickering " Chinese medicine of expellingging wind and relieving convulsion, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, be ground into end altogether with step (1) (2) (3) gained medical material, sieve and be packaged into powder.
6. as claimed in claim 5 " eyelid flickering " expellings wind and relieving convulsion the preparation method of Chinese powder medicine, it is characterized in that, crosses 150-180 mesh sieve (preferred: to cross 160-170 mesh sieve in step (4); Be more preferably: cross 165 mesh sieves).
7. " eyelid flickering " as described in as arbitrary in claim 1-2 expellings wind and relieving convulsion Chinese medicine, and it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria, Radix Codonopsis, Radix Cynanchi Paniculati and Radix Aconiti Lateralis Preparata are cleaned, be placed in soup and soak 50 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) medical material removing impurity will be remained, clean and dry, and be ground into end altogether with step (1) (2) (3) gained medical material and cross 160 mesh sieves, be filled in Capsules, make capsule.
8. as claimed in claim 7 " eyelid flickering " expellings wind and relieving convulsion the preparation method of Chinese medicine capsules, and it is characterized in that, step becomes capsule according to the metric system of 0.3g/ grain in (4).
9. " eyelid flickering " as described in as arbitrary in claim 1-2 expellings wind and relieving convulsion Chinese medicine, and it is characterized in that, be made into pharmaceutically acceptable thick paste, its preparation method is:
(1) get Bulbus Allii Fistulosi and add decocting soup, the Radix Astragali, Rhizoma Chuanxiong, Poria and Radix Codonopsis are cleaned, be placed in soup and soak 25 minutes, pull out, vexed after, cut into slices, dry;
(2) Fructus Rubi is removed handle, sieve dedust bits, are rolled into cake, are placed in parch container, add rice wine and mix thoroughly, and slow fire stir-fries 5-10 minute (preferred: to stir-fry 8 minutes), takes out;
(Cornu Caprae seu Ovis is rasped to end by 3), and add the Mel submergence of medical material weight 5 times, little fire is endured to its variable color, smashs to pieces after flash baking;
(4) by Radix Cynanchi Paniculati, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata and Radix Curcumae, add meter water and do not have medical material 3cm to soak 30-50 minute (preferably: soak 35-45 minute; Be more preferably: soak 40 minutes), take out section and mix with residue medical material, add the water of medical material weight 6 times, decoct 35 minutes, filter to get filtrate;
(5) concentration step (4) gained filtrate is to clear paste, stirs, cool, encapsulate to obtain thick paste after step (1) (2) (3) gained pulverizing medicinal materials is crossed 180 mesh sieves with clear paste.
10. as claimed in claim 9 " eyelid flickering " expellings wind and relieving convulsion the preparation method of traditional Chinese medicine thick paste, and it is characterized in that, the relative density of step (5) clear paste is 1.21-1.23(70 DEG C) (preferred: relative density is 1.22(70 DEG C)).
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| CN101167927A (en) * | 2007-10-25 | 2008-04-30 | 寇连翠 | Traditional Chinese medicine formula for treating eye and face spasm |
| CN102614264A (en) * | 2012-05-02 | 2012-08-01 | 马守云 | Medicine for treating eyelid spasm |
| CN102940745A (en) * | 2012-12-04 | 2013-02-27 | 刘顺慧 | Pill for treating blepharospasm |
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- 2014-12-19 CN CN201410791971.2A patent/CN104524445A/en active Pending
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| CN101167927A (en) * | 2007-10-25 | 2008-04-30 | 寇连翠 | Traditional Chinese medicine formula for treating eye and face spasm |
| CN102614264A (en) * | 2012-05-02 | 2012-08-01 | 马守云 | Medicine for treating eyelid spasm |
| CN102940745A (en) * | 2012-12-04 | 2013-02-27 | 刘顺慧 | Pill for treating blepharospasm |
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