CN104436066A - Blood-nourishing and wind-calming preparation for eyelid twitching and preparation method - Google Patents
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Abstract
The invention discloses a blood-nourishing and wind-calming preparation for eyelid twitching. The preparation is mainly prepared from the following raw materials in parts by weight: 12-25 parts of astragalus membranaceus, 8-15 parts of ligusticum wallichii, 7-14 parts of flos carthami, 6-12 parts of schisandra chinensis, 9-15 parts of fried spina date seeds, 8-12 parts of poria cocos, 6-9 parts of cynanchum paniculatum, 6-9 parts of sheep's or goat's horn, 9-16 parts of alpinia oxyphylla, 10-18 parts of rush, 6-9 parts of polygala tenuifolia, 5-10 parts of radix curcumae and 8-12 parts of malt. The preparation disclosed by the invention is prepared from purely natural animal and plant materials, so that the preparation is safe and free of side effects. In light of a principle of traditional Chinese medicine, due to dialectical therapy, the preparation has the functions of enriching blood and promoting the circulation of qi, nourishing qi to generate fluid and tonifying spleen and quieting heart and is stable in component, reliable in curative effect and high in clinical cure rate.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation and preparation method thereof.
Background technology
Born of the same parents' eyelid tramp does not independently lead the oculopathy of dragging and beating for main manifestations with eyelid, is commonly called as tie of the orbicular muscie or eyelid flickering.Medically be called eyelid twitch, refer to that upper eye lid or lower eyelid can not move by automatic control ground Chu Ti Shun.Clinically be more common in adult.If occur once in a while, not heart treatment, can spontaneous recovery; If beat, overfrequency or jumping for a long time incessantly, then must be recuperated under medical treatment.Primary disease is similar to the blepharospasm of western medicine.Upper eye lid or lower eyelid are beated, time dredge time-frequency, can not automatic control.General overwork, watching for a long time, beat when not having enough sleep more frequent, after rest, symptom can alleviate or disappear.Born of the same parents' eyelid is beated severe patient, together with half side facial muscle, eyebrow, bicker all Shun move.With the passing of time do not heal, probably have inclined change.Often when born of the same parents' eyelid tramp, the conscious discomfort of patient, but check that born of the same parents' eyelid outward appearance is normal.Primary disease is many, and because of deficiency of both QI and blood or prolonged illness imbalance, labor is looked forward or upwards excessively, damage heart spleen, deficiency of both the heart and spleen, and muscles loses supports and moves.Becoming has because of liver spleen blood deficiency, with the passing of time raw wind, stirring-up of pathogenic wind in the interior resulting from deficiency, leads and drags born of the same parents' eyelid and tramp.Primary disease is fallen ill in born of the same parents' eyelid, in close relations with conscience spleen.Dialectical based on deficiency syndrome.Born of the same parents' eyelid tramp, fatigue increases the weight of, vexed insomnia, and lack of appetite Mental fatigue person is heart spleen blood deficiency.Twitching of the eyelid without stopping can not automatic control person be wind syndrome due to blood-deficiency.Therapeutic Principle is tonic heart spleen, nourishing blood to stop wind syndrome.Publication number CN 103446289 A(application number 201210186410.0) Chinese patent literature disclose a kind of combination of Chinese medicine for the treatment of eyelid flickering, be made up of Fructus Forsythiae, Fructus Arctii, Rhizoma Et Radix Notopterygii, Herba Menthae, Radix Et Rhizoma Rhei, Radix Paeoniae Rubra, Radix Saposhnikoviae etc.Publication number CN 103301286 A(application number 201310247489.8) Chinese patent literature disclose one and treat that eye is puckery, twitching of the eyelid color medicine, composition comprises Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Fructus Lycii, Flos Chrysanthemi, Fructus Viticis, Rhizoma Dioscoreae, Fructus Rubi, clam worm, Rhizoma Dioscoreae, Cortex Moutan, Rhizoma Alismatis, Radix Stephaniae Tetrandrae, Scorpio.
Western medicine is for the treatment not medicine targetedly of this disease, the traditional Chinese medical science by this sick dialectical be heart spleen blood-deficiency type and wind syndrome due to blood-deficiency type, etiotropic difference, adopt different treatment formula, but the research in this is also less at present, and effect is also unsatisfactory in existing formula, therefore, the Chinese medicine formula working out better efficacy is further needed.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation and the preparation method of preparing simple, taking convenience.
Technical scheme of the present invention is:
Born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs, is weight portion: Radix Astragali 12-25, Rhizoma Chuanxiong 8-15, Flos Carthami 7-14, Fructus Schisandrae Chinensis 6-12, Semen Ziziphi Spinosae (parched) 9-15, Poria 8-12, Radix Cynanchi Paniculati 6-9 Cornu Caprae seu Ovis 6-9, Fructus Alpiniae Oxyphyllae 9-16, Medulla Junci 10-18, Radix Polygalae 6-9, Radix Curcumae 5-10, Fructus Hordei Germinatus 8-12.
In preferred scheme, Radix Astragali 17-20, Rhizoma Chuanxiong 9-14, Flos Carthami 9-12, Fructus Schisandrae Chinensis 8-10, Semen Ziziphi Spinosae (parched) 10-14, Poria 9-11, Radix Cynanchi Paniculati 7-8 ， Cornu Caprae seu Ovis 7-8, Fructus Alpiniae Oxyphyllae 10-15, Medulla Junci 12-16, Radix Polygalae 7-8, Radix Curcumae 6-9, Fructus Hordei Germinatus 9-11.
Be more preferably, the Radix Astragali 13.5, Rhizoma Chuanxiong 11.5, Flos Carthami 10.5, Fructus Schisandrae Chinensis 9, Semen Ziziphi Spinosae (parched) 12, Poria 10, Radix Cynanchi Paniculati 7.5 ， Cornu Caprae seu Ovis 7.5, Fructus Alpiniae Oxyphyllae 12.5, Medulla Junci 14, Radix Polygalae 7.5, Radix Curcumae 7.5, Fructus Hordei Germinatus 10.
Present invention also offers the preparation method above-mentioned born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation being made pharmaceutically acceptable pill, decoction, powder and unguentum.
The preparation method of described born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation pill is:
(1) extracting liquorice, adds decocting soup, removes slag, and adds clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize and sieve together with step (1) (2) (3) made medical material, add wetting agent mixing, molding, molding, capping, drying, sieve, coating polishing, drying, obtain pill.
The preparation method of described born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation pill, the quality of step (1) Radix Glycyrrhizae is 0.3 times of Radix Polygalae.
The preparation method of described decoction is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) (3) made medical material, soak 40-60 minute, then big fire is boiled, and a turn little fire decocts 30-50 minute, and (preferred, 35-45 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 40 minutes), close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
The preparation method of described born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation decoction, step (4) is soaked 45-55 minute (preferred, to soak 50 minutes).
The preparation method of described powder is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize together with step (1) (2) (3) made medical material, add the sucrose mixing of medicated powder quality 0.4 times, pulverize and sieve, obtain powder.
The preparation method of described born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation powder, step (4) was pulverized 180-240 mesh sieve and (preferably, was pulverized 200-220 mesh sieve; Be more preferably, pulverized 210 mesh sieves).
The preparation method of described unguentum is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry, pulverized 180 mesh sieves;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) made medical material, soaks and (preferably, soaks 45-55 minute in 40-60 minute; Be more preferably, soak 50 minutes), then big fire is boiled, and a turn little fire decocts 30-50 minute, and (preferred, 35-45 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 40 minutes), close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, heating is concentrated into clear paste, adds step (3) made medicated powder and one spoonful of vinegar, and mixing, obtains unguentum.
The preparation method of described born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation unguentum, the relative density of step (5) clear paste is 1.20-1.26(60 DEG C) (preferred, the relative density of clear paste is 1.22-1.24(60 DEG C); Be more preferably, the relative density of clear paste is 1.23(60 DEG C)).
Born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation compatibility provided by the invention is reasonable, and preparation is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, pure natural animals and plants material obtains, and ensures that safety has no side effect;
2, according to Chinese medicine principle, dialectically to treat, there is circulation of qi promoting of enriching blood, supplementing QI for promoting the production of body fluid, spleen invigorating mind calming effect;
3, stable components, curative effect is reliable, and clinical cure rate is high.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Radix Astragali: base is former: be the dry root of leguminous plant Radix Astagali or Radix Astragali.Nature and flavor: sweet, temperature.Gui Jing: return lung, spleen channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Rhizoma Chuanxiong: base is former: be the dry rhizome of samphire Rhizoma Chuanxiong.Nature and flavor: pungent, temperature.Gui Jing: return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Flos Carthami: base is former: be the dried floral of feverfew Flos Carthami.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Fructus Schisandrae Chinensis: base is former: be the dry mature fruit of magnoliaceae schisandra or schisandra chinensis.Nature and flavor: sour, sweet, temperature.Gui Jing: return lung, the heart, kidney channel.Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Semen Ziziphi Spinosae (parched): Semen Ziziphi Spinosae: base is former: be the seed of Rhamnaceae plant Ziziphi Spinosae.Get clean Semen Ziziphi Spinosae, put in pot to fry with slow fire and heave to surface is micro-, color is micro-to be deepened, and when having fragrance to overflow, taking-up cools, and obtains Semen Ziziphi Spinosae (parched).Nature and flavor: sweet are flat.Gui Jing: enter the heart, spleen, liver, gallbladder meridian.Function cures mainly: nourishing the liver, and mind calming is calmed the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.
Poria: base is former: be the dry sclerotia of On Polyporaceae Poria.Nature and flavor: sweet, light are flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Cynanchi Paniculati: base is former: be the dry root and rhizome of asclepiadaceae Cynanchum plant Radix Cynanchi Paniculati.Nature and flavor: pungent, temperature.Gui Jing: return liver, stomach warp.Function cures mainly: removing dampness of dispeling the wind, antalgesic-antipruritic.For rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down, urticaria, eczema.
Cornu Caprae seu Ovis: base is former: be the angle of bovid male goat or male sheep.Nature and flavor: bitter in the mouth; Salty; Cold in nature.Gui Jing: liver; Heart channel.Function cures mainly: heat clearing away; Relieving convulsion; Improving eyesight; Removing toxic substances.Main headache due to pathogenic wind-heat; Epidemic febrile disease heating coma; Unhappy; Spit blood; Pediatric epilepsy scared; Palpitation with fear; Optic atrophy; Carbuncle sore tumefacting virus.
Fructus Alpiniae Oxyphyllae: base is former: be the fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae.Nature and flavor: acrid in the mouth; Warm in nature.Gui Jing: spleen; Kidney channel.Function cures mainly: warming spleen and stopping diarrhaly take the photograph saliva; Warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Main Deficiency and coldness of spleen and stomach; Vomiting; Have loose bowels; Coldly in abdomen to educate; The many salivas of mouth; Enuresis due to deficiency of the kidney; Frequent micturition; Seminal emission; Nebulousurine.
Medulla Junci: base is former: be the dry stem pith of rush family plant Medulla Junci.Nature and flavor: sweet, light, are slightly cold.Gui Jing: GUIXIN, lung, small intestine meridian.Function cures mainly: clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.
Radix Polygalae: base is former: be the dry root of milk wort Radix Polygalae or ovum leaf Radix Polygalae.Nature and flavor: bitter, pungent, warm.Gui Jing: GUIXIN, kidney, lung meridian.Function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Radix Curcumae: base is former: be the dried root of zingiberaceous plant RADIX CURCUMAE, Rhizoma Curcumae Longae, Guangxi zedoary or Rhizoma Curcumae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, the heart, lung meridian.Function cures mainly: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Fructus Hordei Germinatus: base is former: for the mature fruit of grass Fructus Hordei Vulgaris is through germinateing drying and obtaining.Nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Function cures mainly: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.
embodiment 1born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs: Radix Astragali 12g, Rhizoma Chuanxiong 8g, Flos Carthami 7g, Fructus Schisandrae Chinensis 6g, Semen Ziziphi Spinosae (parched) 9g, Poria 8g, Radix Cynanchi Paniculati 6g ， Cornu Caprae seu Ovis 6g, Fructus Alpiniae Oxyphyllae 9g, Medulla Junci 10g, Radix Polygalae 6g, Radix Curcumae 5g, Fructus Hordei Germinatus 8g.
The preparation method of above-mentioned born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation pill is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day, then Steam by water bath 15 minutes with ginger decoction, then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize and sieve together with step (1) (2) (3) made medical material, add wetting agent mixing, molding, molding, capping, drying, sieve, coating polishing, drying, obtain pill.
embodiment 2born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs: Radix Astragali 25g, Rhizoma Chuanxiong 15g, Flos Carthami 14g, Fructus Schisandrae Chinensis 12g, Semen Ziziphi Spinosae (parched) 15g, Poria 12g, Radix Cynanchi Paniculati 9g ， Cornu Caprae seu Ovis 9g, Fructus Alpiniae Oxyphyllae 16g, Medulla Junci 18g, Radix Polygalae 9g, Radix Curcumae 10g, Fructus Hordei Germinatus 12g.
The preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation decoction is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day, then Steam by water bath 20 minutes with ginger decoction, then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) (3) made medical material, soak 50 minutes, then big fire is boiled, and turns little fire and decocts 40 minutes, close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
Model case: xxx, female, 26 years old.Main suit: most immediate cause and grandmother are at loggerheads with sb., mood is smooth, vexed insomnia, inappetence, and nearly 3 days, tramp appearred in right eyelid, originally every day 3-4 time, and day by day increase the weight of, Dual-eyelid all starts tramp, time dredge time-frequency, can not automatic control, then seek medical advice.Time medical, eyelid is pale, and conjunctiva is slightly congested, thin white fur of tongue, thready and stringy pulse, is diagnosed as QI and blood pair and loses, asthenic fire is disturbed caused eyelid tramp.
Take the present embodiment gained born of the same parents eyelid tramp nourishing blood to stop wind syndrome preparation decoction, each 30-50ml(is warm), every day 2 times, 7 days courses for the treatment of.Take two days later, eyelid tramp obviously alleviates, one day tramp 2-3 time, and appetite is recovered, and after taking a course for the treatment of, patient's eyelid tramp stops, happy, recovery from illness.
embodiment 3born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs: Radix Astragali 17g, Rhizoma Chuanxiong 9g, Flos Carthami 9g, Fructus Schisandrae Chinensis 8g, Semen Ziziphi Spinosae (parched) 10g, Poria 9g, Radix Cynanchi Paniculati 7g ， Cornu Caprae seu Ovis 7g, Fructus Alpiniae Oxyphyllae 10g, Medulla Junci 12g, Radix Polygalae 7g, Radix Curcumae 6g, Fructus Hordei Germinatus 9g.
The preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation powder is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day, then Steam by water bath 20 minutes with ginger decoction, then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize together with step (1) (2) (3) made medical material, add the sucrose mixing of medicated powder quality 0.4 times, pulverized 210 mesh sieves, and obtained powder.
Model case: xxx, man, 56 years old.Before 5 days, the appearance Dual-eyelid of not clear inducement is alternately beated, every day 7 times, each lasting 15-20 minute, and originally do not take notice of, rear sense discomfort takes cod-liver oil, without any effect, nearly 2 days, beat frequent, be nervous, insomnia, appetite also declines, and constipation increases the weight of, medical check then.Time medical, the puffiness of the eyes, conjunctival congestion, there is sclerosis of blood vessels on optical fundus, pale tongue, white and thin fur, thready and stringy pulse, is diagnosed as insufficiency of the spleen, liver-wind is disturbed caused eyelid tramp.
Take the present embodiment gained born of the same parents eyelid tramp nourishing blood to stop wind syndrome preparation powder, adopt twice daily, each one bag (about 4g), with warm boiled water, 7 days courses for the treatment of.After taking 3 days, eyelid tramp frequency and every day tramp number of times obviously less, appetite recover, sleep improvement, take to a course for the treatment of, the many symptoms of patient all disappear completely, recovery from illness, follow up a case by regular visits in 1 year and do not recur.
embodiment 4born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs: Radix Astragali 20g, Rhizoma Chuanxiong 14g, Flos Carthami 12g, Fructus Schisandrae Chinensis 10g, Semen Ziziphi Spinosae (parched) 14g, Poria 11g, Radix Cynanchi Paniculati 8g ， Cornu Caprae seu Ovis 8g, Fructus Alpiniae Oxyphyllae 15g, Medulla Junci 16g, Radix Polygalae 8g, Radix Curcumae 9g, Fructus Hordei Germinatus 11g.
The preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation unguentum is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day, then Steam by water bath 20 minutes with ginger decoction, then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry, pulverized 180 mesh sieves;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) made medical material, soak 50 minutes, then big fire is boiled, and turns little fire and decocts 40 minutes, close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, to be concentrated into relative density be 1.23(60 DEG C in heating) clear paste, add step (3) made medicated powder and one spoonful of vinegar, mixing, obtains unguentum.
Model case: xxx, man, 23 years old.Often stay up late and play games, sometimes because play games and can forget one's meals.Main suit: recent one week, tramp appearred in upper eye lid, plays junior one sky tramp 4-6 time, after increase to more than 10 times, and tramp speed increases, can not automatic control, and after rest, symptom alleviates to some extent, but for a long time to looking computer, upper eye lid tramp is endlessly.Medical check, is diagnosed as by wind syndrome due to blood-deficiency upper eye lid tramp.
Take the present embodiment gained born of the same parents eyelid tramp nourishing blood to stop wind syndrome preparation unguentum, adopt twice daily, each one spoonful (about 5g), with warm boiled water, 7 days courses for the treatment of.Take two days later, tramp alleviates, every day upper eye lid tramp 5-7 time, appetite increase, continue to take to a course for the treatment of, patient's malaise symptoms all disappears, recovery from illness.
embodiment 5born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is prepared from primarily of following bulk drugs: Radix Astragali 13.5g, Rhizoma Chuanxiong 11.5g, Flos Carthami 10.5g, Fructus Schisandrae Chinensis 9g, Semen Ziziphi Spinosae (parched) 12g, Poria 10g, Radix Cynanchi Paniculati 7.5g ， Cornu Caprae seu Ovis 7.5g, Fructus Alpiniae Oxyphyllae 12.5g, Medulla Junci 14g, Radix Polygalae 7.5g, Radix Curcumae 7.5g, Fructus Hordei Germinatus 10g.
The preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation pill is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day, then Steam by water bath 20 minutes with ginger decoction, then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize and sieve together with step (1) (2) (3) made medical material, add wetting agent mixing, molding, molding, capping, drying, sieve, coating polishing, drying, obtain pill.
test example 1the clinical practice of embodiment 5 gained born of the same parents eyelid tramp nourishing blood to stop wind syndrome preparation pill:
355 routine patients are screened, wherein women 168 example, male 187 example, oldest 62 years old, minimal ages 20 years old, 43.6 years old mean age in hospital-based outpatient eye clinic case.Diagnostic criteria: upper eye lid or lower eyelid independently do not lead to drag beats, or and eyebrow border, buccal, can not arbitrarily control; Born of the same parents' eyelid skin is normal, and without swelling pain, eye outward appearance end is good.
Patient is divided into two groups at random, experimental group and matched group, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes embodiment 5 products obtained therefrom, and every day takes twice, each 3-5 (adjusting to some extent depending on concrete condition), 7 days courses for the treatment of, and matched group takes other medicine (conventional medication such as carbamazepine, vitamin B1, QIJU DIHUANG WAN).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: cure: take a course for the treatment of of this product, upper eye lid or palpebra inferior tramp stop, can automatic control; Effective: take a course for the treatment of of this product, upper eye lid or palpebra inferior tramp are controlled substantially; Effective: to take a course for the treatment of of this product, upper eye lid or palpebra inferior tramp have and obviously alleviate, and occasionally have tramp, but tramp sense are lighter; Invalid: take a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
The therapeutic outcome of two groups of patients after a course for the treatment of treated by table 1
As shown in Table 1: the experimental group patient taking embodiment 5 gained pill, curing number of cases has 165 examples (64.7%), and symptom obtains patient 52 example (20.4%) controlled, and the patient that symptom takes a turn for the better has 36 examples (14.1%), draws the total effective rate 99.2% of experimental group; The total effective rate of matched group is 84%, and therapeutic effect can not show a candle to the good of experimental group.The therapeutic effect of visible embodiment 5 products obtained therefrom to born of the same parents' eyelid is significantly higher than the conventional medication that matched group is taken.
Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding that the present invention selects; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; Flos Carthami promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of Fructus Schisandrae Chinensis convergence; Semen Ziziphi Spinosae (parched) nourishing the liver mind calming; Poria spleen invigorating mind calming, promoting diuresis to eliminate damp pathogen; Cornu Caprae seu Ovis heat clearing away, relieving convulsion, improving eyesight; Fructus Alpiniae Oxyphyllae warming the spleen warming the kidney; Medulla Junci clearing away heart-fire, diuresis; Radix Polygalae is calmed the nerves Fructus Alpiniae Oxyphyllae; Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Fructus Hordei Germinatus spleen benefiting and stimulating the appetite, promote qi circulation digestion promoting, multiple medical material reasonable compatibility, collaborative performance is enriched blood the effects such as circulation of qi promoting, supplementing QI for promoting the production of body fluid, spleen invigorating mind calming, remarkable to born of the same parents' eyelid tramp therapeutic effect.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation, is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Radix Astragali 12-25, Rhizoma Chuanxiong 8-15, Flos Carthami 7-14, Fructus Schisandrae Chinensis 6-12, Semen Ziziphi Spinosae (parched) 9-15, Poria 8-12, Radix Cynanchi Paniculati 6-9 ， Cornu Caprae seu Ovis 6-9, Fructus Alpiniae Oxyphyllae 9-16, Medulla Junci 10-18, Radix Polygalae 6-9, Radix Curcumae 5-10, Fructus Hordei Germinatus 8-12.
2. born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation as claimed in claim 1, is characterized in that, Radix Astragali 17-20, Rhizoma Chuanxiong 9-14, Flos Carthami 9-12, Fructus Schisandrae Chinensis 8-10, Semen Ziziphi Spinosae (parched) 10-14, Poria 9-11, Radix Cynanchi Paniculati 7-8 Cornu Caprae seu Ovis 7-8, Fructus Alpiniae Oxyphyllae 10-15, Medulla Junci 12-16, Radix Polygalae 7-8, Radix Curcumae 6-9, Fructus Hordei Germinatus 9-11 are (preferred, the Radix Astragali 13.5, Rhizoma Chuanxiong 11.5, Flos Carthami 10.5, Fructus Schisandrae Chinensis 9, Semen Ziziphi Spinosae (parched) 12, Poria 10, Radix Cynanchi Paniculati 7.5 ， Cornu Caprae seu Ovis 7.5, Fructus Alpiniae Oxyphyllae 12.5, Medulla Junci 14, Radix Polygalae 7.5, Radix Curcumae 7.5, Fructus Hordei Germinatus 10).
3. the born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) extracting liquorice, adds decocting soup, removes slag, and adds clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize and sieve together with step (1) (2) (3) made medical material, add wetting agent mixing, molding, molding, capping, drying, sieve, coating polishing, drying, obtain pill.
4. the preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation pill as claimed in claim 3, it is characterized in that, the quality of step (1) Radix Glycyrrhizae is 0.3 times of Radix Polygalae.
5. the born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) (3) made medical material, soak 40-60 minute, then big fire is boiled, and a turn little fire decocts 30-50 minute, and (preferred, 35-45 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 40 minutes), close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
6. the preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation decoction as claimed in claim 5, is characterized in that, step (4) is soaked 45-55 minute (preferred, to soak 50 minutes).
7. the born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry;
(4) get other medical material decontaminations, clean, dry, pulverize together with step (1) (2) (3) made medical material, add the sucrose mixing of medicated powder quality 0.4 times, pulverize and sieve, obtain powder.
8. the preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation powder as claimed in claim 7, is characterized in that, step (4) was pulverized 180-240 mesh sieve and (preferably, pulverized 200-220 mesh sieve; Be more preferably, pulverized 210 mesh sieves).
9. the born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) extracting liquorice (0.3 times of Radix Polygalae quality), adds decocting soup, removes slag, add clean Radix Polygalae, simmers in water to soup and exhausts, take out, dry;
(2) get Radix Curcumae decontamination to clean, soak 1 day with ginger decoction, then Steam by water bath 15-25 minute (preferred, Steam by water bath 17-23 minute; Be more preferably, Steam by water bath 20 minutes), then roast to seventy percent dry, pour in the hot pot that quality of medicinal material 0.2 times of Testa Tritici is housed, urgent stir-fry to medical material dark yellow of useing force is degree, and sieve goes to wheat bran and ash end, cools;
(3) Qu Cornu Caprae seu Ovis decontaminations, smash, are placed in parch container, with slow fire heating, fry to surface coke black, inner burnt brown, take out, dry, pulverized 180 mesh sieves;
(4) by other medical materials (except Radix Cynanchi Paniculati), decontamination is cleaned, and is placed in non iron container together with step (1) (2) made medical material, soaks and (preferably, soaks 45-55 minute in 40-60 minute; Be more preferably, soak 50 minutes), then big fire is boiled, and a turn little fire decocts 30-50 minute, and (preferred, 35-45 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 40 minutes), close fire and add Radix Cynanchi Paniculati in first 20 minutes, filter, collect filtrate;
(5) by step (4) remaining filtering residue, add the water not having medical material 3cm, decoct 40 minutes, filter, merge twice filtrate, heating is concentrated into clear paste, adds step (3) made medicated powder and one spoonful of vinegar, and mixing, obtains unguentum.
10. the preparation method of born of the same parents' eyelid tramp nourishing blood to stop wind syndrome preparation unguentum as claimed in claim 9, it is characterized in that, the relative density of step (5) clear paste is 1.20-1.26(60 DEG C) (preferred, the relative density of clear paste is 1.22-1.24(60 DEG C); Be more preferably, the relative density of clear paste is 1.23(60 DEG C)).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410792138.XA CN104436066A (en) | 2014-12-19 | 2014-12-19 | Blood-nourishing and wind-calming preparation for eyelid twitching and preparation method |
Applications Claiming Priority (1)
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| CN101167927A (en) * | 2007-10-25 | 2008-04-30 | 寇连翠 | Traditional Chinese medicine formula for treating eye and face spasm |
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| CN101167927A (en) * | 2007-10-25 | 2008-04-30 | 寇连翠 | Traditional Chinese medicine formula for treating eye and face spasm |
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| Title |
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| 李晓华等: "归脾汤加减合针刺治疗眼睑痉挛40例", 《中国中医药科技》 * |
| 汪涤清: "《汪氏中医眼科临床经验》", 31 December 2005, 湖北科学技术出版社 * |
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