CN104524352A - Traditional Chinese medicine for invigorating spleen and increasing appetite for animals - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for invigorating spleen and increasing appetite for animals. The traditional Chinese medicine is prepared from the following medicinal raw materials, by weight, 50-70 parts of haw, 30-40 parts of dried orange peel, 50-60 parts of malt, 20-40 parts of betel nut, 30-50 parts of Poria cocos, 10-30 parts of white peony root, 10-30 parts of licorice, 40-60 parts of Radix Astragali, 20-35 parts of wheat bran, 40-50 parts of apricot kernel, 15-30 parts of magnolia cortex, 40-60 parts of sophora flavescens and 30-50 parts of radish seed. In comparison with the prior art, haw, dried orange peel and malt are used as monarch drugs, betel nut, Poria cocos, white peony root and licorice are used as ministerial drugs, Radix Astragali, wheat bran and apricot kernel are used as adjuvant drugs, and magnolia cortex, sophora flavescens and radish seed are used as conductant drugs in the invention. The invention provides a traditional Chinese medicine for invigorating spleen and increasing appetite for animals. The traditional Chinese medicine has characteristics of promoting digestion, relieving stasis, replenishing qi to invigorate the spleen, regulating qi-flowing and stimulating one's appetite, and has no toxic or side effect. Meanwhile, production cost is low, and the processing technology is simple. By the use of the traditional Chinese medicine, immunity of livestock and poultry can be effectively raised, and yield of livestock and poultry can be increased.

Description

A kind of Chinese medicine for animal spleen benefiting and stimulating the appetite

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for animal spleen benefiting and stimulating the appetite and preparation method thereof.

Background technology

Animal alimentary canal diseases belongs to commonly encountered diseases, frequently-occurring disease, has the features such as sickness rate is high, scope wide, many, the easy recurrence of sick kind.Find in investigation in recent years, the animal farm that great majority are raised scattered, continue to use comparatively traditional yard feeding pattern, raise competence is not high, especially the quality and quantity of feedstuff can not meet the needs of animal, and pursue high yield only by the amount increasing concentrated feed, result just causes the generation of digestive tract disease, cause the generation of metabolic disease simultaneously, huge loss is caused to peasant household.The medicine of conventional treatment is according to different symptoms: can throw tartar emetic acid antimony potassium and Semen Momordicae fourth for strengthening front gastric peristalsis, coordinating cud massage and pulling motion simultaneously; Quiet note can be added with glucose saline, sodium bicarbonate, At when presenting acidosis symptom; Sometimes also antibiosis anti-inflammatory drug is used, as chloromycetin, chlortetracycline, berberine, sulfadiazine, artificial salt etc.But these medicines are controlled table and do not controlled root, can only solve of short duration pain, can not be cure in essence.

Summary of the invention

The technical problem to be solved in the present invention is that the medicine for the treatment of animal alimentary canal diseases at present takes stopgap measures and do not control root, of short duration pain can only be solved, can not being cure in essence, for solving the problem, the invention provides a kind of Chinese medicine for animal spleen benefiting and stimulating the appetite and preparation method thereof.

The object of the invention is to realize in the following manner:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 50-70 part, Pericarpium Citri Reticulatae 30-40 part, Fructus Hordei Germinatus 50-60 part, Semen Arecae 20-40 part, Poria 30-50 part, Radix Paeoniae Alba 10-30 part, Radix Glycyrrhizae 10-30 part, Radix Astragali 40-60 part, Testa Tritici 20-35 part, Semen Armeniacae Amarum 40-50 part, Cortex Magnoliae Officinalis 15-30 part, Radix Sophorae Flavescentis 40-60 part, Semen Raphani 30-50 part.

Be made up of the crude drug of following weight portion: Fructus Crataegi 60 parts, Pericarpium Citri Reticulatae 35 parts, 55 parts, Fructus Hordei Germinatus, Semen Arecae 30 parts, 40 parts, Poria, the Radix Paeoniae Alba 20 parts, 20 parts, Radix Glycyrrhizae, the Radix Astragali 50 parts, 25 parts, Testa Tritici, 45 parts, Semen Armeniacae Amarum, Cortex Magnoliae Officinalis 20 parts, Radix Sophorae Flavescentis 50 parts, Semen Raphani 40 parts.

The present invention selects effect of raw material to be summarized as follows:

Fructus Crataegi: property is sour, sweet, tepor; Return spleen, stomach, Liver Channel, there is the effects such as digestion promoting, blood pressure lowering, blood fat reducing, antioxidation; Promoting digestion and invigorating the stomach, circulation of qi promoting scattered silt; Cure mainly eating accumulation, abdominal distention, dysentery etc.

Pericarpium Citri Reticulatae: acrid in the mouth is bitter, warm in nature, has effect of the spleen invigorating of ventilation, drying dampness to eliminate phlegm, the greasy lasting of solution, stopping nausea and vomiting by lowering the adverse flow of QI.Pericarpium Citri Reticulatae contains limonoid, and this limonoid taste is gentle, soluble in water, in addition, Pericarpium Citri Reticulatae contains the compositions such as volatile oil, hesperidin, vitamin B, C, and the volatile oil contained by it has gentle stimulation to gastrointestinal tract, can the secretion of facilitating digestion liquid, get rid of pneumatosis in intestinal tube, increase appetite.

Fructus Hordei Germinatus: starch-containing catabolic enzyme, second kind and vitamin C etc., has soothing the liver awake stomach, helps digestion except effects such as full, regulating middle-JIAO and making the adverse QI downwards.

Semen Arecae: property is bitter, pungent, temperature; Return stomach, large intestine channel, expelling intestinal worms and removing food stagnancy, therapeutic method to keep the adverse QI flowing downwards row water, preventing the attack (or recurrence) of malaria; Cure mainly malnutrition due to parasitic infestation, dyspepsia, abdominal distention, after dysentery heavily etc.

Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.

The Radix Paeoniae Alba: property is bitter, sour, is slightly cold; Return liver, spleen channel.There is antiinflammatory, analgesia, enhancing immunologic function, resisting pathogenic microbes, CNS inhibition, anoxia enduring, protect the liver and detoxify, the effect such as antimutagenic and antitumor; Nourish blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver; Cure mainly blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and has a headache dizzy.

Radix Glycyrrhizae: property is put down, and sweet in the mouth, returns 12 warps, has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.Clinical practice divides, and " life is used " is not with " processed with honey ".Raw with curing mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.; Processed with honey cures mainly spleen and stomach function and goes down, and large loose stool is thin, weak heating and cough, cardiopalmus etc.

The Radix Astragali: property is sweet, warm; Return lung, spleen channel, have and strengthen immune system, slow down aging, the effects such as antioxidation, enhancing cardiovascular system, antithrombotic, antiviral, antiinflammatory and analgesia; Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; Cure mainly the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle difficulty is burst or is burst for a long time and do not hold back.

Testa Tritici: the seed coat under sieving after flour got by Semen Tritici aestivi mill, has and control sweating due to debility, night sweat, let out profit, diabetes, stomatitis, herpes simplex, injured, the effects such as rheumatic arthralgia.

Semen Armeniacae Amarum: bitter temperature lung qi dispersing, loosening bowel to relieve constipation, the Semen Armeniacae Amarum bitter in the mouth therapeutic method to keep the adverse QI flowing downwards, and be rich in fatty oil.Fatty oil can improve the lubrication of intestinal contents to mucosa, therefore Semen Armeniacae Amarum has the function of loosening bowel to relieve constipation.

Cortex Magnoliae Officinalis: nature and flavor are bitter, pungent, temperature, returning through entering spleen, lung, stomach, large intestine four warp, having effect of circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, lowering the adverse QI to relieve asthma.

Radix Sophorae Flavescentis: cold in nature, has heat clearing and damp drying, effect of parasite killing, and Radix Sophorae Flavescentis ether extract and ethanol extract have stronger bacteriostasis to staphylococcus aureus; Radix Sophorae Flavescentis water logging agent has inhibitory action to trichophyton, Trichophyton concentricunm, trichophyton, Du's big belly difficult to understand little spore tinea bacterium etc.

Semen Raphani: have another name called Semen Raphani, trailing plants white chessman, Semen Raphani etc., for the mature seed of crucifer Radix Raphani, enter spleen, stomach, lung meridian, can be helped digestion de-swelling, effect is remarkable, there is the title of " rush wall fall wall ", can be used for being used for the treatment of retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant stops up and breath with cough.

Relative to prior art, the present invention with Fructus Crataegi, Pericarpium Citri Reticulatae, Fructus Hordei Germinatus for monarch drug, Semen Arecae, Poria, the Radix Paeoniae Alba, Radix Glycyrrhizae are ministerial drug, the Radix Astragali, Testa Tritici, Semen Armeniacae Amarum are adjuvant drug, and Cortex Magnoliae Officinalis, Radix Sophorae Flavescentis, Semen Raphani, for making medicine, provide a kind of Chinese medicine for animal spleen benefiting and stimulating the appetite, there is promoting digestion and removing stagnation, replenishing QI to invigorate the spleen, appetizing of regulating the flow of vital energy, the feature such as have no side effect, production cost is low simultaneously, processing technique simple, effectively can improve poultry domestic animal immunity, improves poultry zootechnical yield.

Detailed description of the invention

Embodiment 1:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 50-70 part, Pericarpium Citri Reticulatae 30-40 part, Fructus Hordei Germinatus 50-60 part, Semen Arecae 20-40 part, Poria 30-50 part, Radix Paeoniae Alba 10-30 part, Radix Glycyrrhizae 10-30 part, Radix Astragali 40-60 part, Testa Tritici 20-35 part, Semen Armeniacae Amarum 40-50 part, Cortex Magnoliae Officinalis 15-30 part, Radix Sophorae Flavescentis 40-60 part, Semen Raphani 30-50 part.Through super-dry, pulverize, sieve, mix, namely packaging process can be made into.

Embodiment 2:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 50g, Pericarpium Citri Reticulatae 30g, Fructus Hordei Germinatus 50g, Semen Arecae 20g, Poria 30g, Radix Paeoniae Alba 10g, Radix Glycyrrhizae 10g, Radix Astragali 40g, Testa Tritici 20g, Semen Armeniacae Amarum 40g, Cortex Magnoliae Officinalis 15g, Radix Sophorae Flavescentis 40g, Semen Raphani 30g.The other the same as in Example 1.

Embodiment 3:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 52g, Pericarpium Citri Reticulatae 31g, Fructus Hordei Germinatus 51g, Semen Arecae 22g, Poria 32g, Radix Paeoniae Alba 12g, Radix Glycyrrhizae 12g, Radix Astragali 42g, Testa Tritici 22g, Semen Armeniacae Amarum 41g, Cortex Magnoliae Officinalis 16g, Radix Sophorae Flavescentis 42g, Semen Raphani 32g.The other the same as in Example 1.

Embodiment 4:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 54g, Pericarpium Citri Reticulatae 32g, Fructus Hordei Germinatus 52g, Semen Arecae 24g, Poria 34g, Radix Paeoniae Alba 14g, Radix Glycyrrhizae 14g, Radix Astragali 44g, Testa Tritici 24g, Semen Armeniacae Amarum 42g, Cortex Magnoliae Officinalis 18g, Radix Sophorae Flavescentis 44g, Semen Raphani 34g.The other the same as in Example 1.

Embodiment 5:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 56g, Pericarpium Citri Reticulatae 33g, Fructus Hordei Germinatus 53g, Semen Arecae 26g, Poria 36g, Radix Paeoniae Alba 16g, Radix Glycyrrhizae 16g, Radix Astragali 46g, Testa Tritici 26g, Semen Armeniacae Amarum 43g, Cortex Magnoliae Officinalis 20g, Radix Sophorae Flavescentis 46g, Semen Raphani 36g.The other the same as in Example 1.

Embodiment 6:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 58g, Pericarpium Citri Reticulatae 34g, Fructus Hordei Germinatus 54g, Semen Arecae 28g, Poria 38g, Radix Paeoniae Alba 18g, Radix Glycyrrhizae 18g, Radix Astragali 48g, Testa Tritici 28g, Semen Armeniacae Amarum 44g, Cortex Magnoliae Officinalis 22g, Radix Sophorae Flavescentis 48g, Semen Raphani 38g.The other the same as in Example 1.

Embodiment 7:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 60g, Pericarpium Citri Reticulatae 35g, Fructus Hordei Germinatus 55g, Semen Arecae 30g, Poria 40g, Radix Paeoniae Alba 20g, Radix Glycyrrhizae 20g, Radix Astragali 50g, Testa Tritici 30g, Semen Armeniacae Amarum 45g, Cortex Magnoliae Officinalis 24g, Radix Sophorae Flavescentis 50g, Semen Raphani 40g.The other the same as in Example 1.

Embodiment 8:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 62g, Pericarpium Citri Reticulatae 36g, Fructus Hordei Germinatus 56g, Semen Arecae 32g, Poria 42g, Radix Paeoniae Alba 22g, Radix Glycyrrhizae 22g, Radix Astragali 52g, Testa Tritici 32g, Semen Armeniacae Amarum 46g, Cortex Magnoliae Officinalis 25g, Radix Sophorae Flavescentis 52g, Semen Raphani 42g.The other the same as in Example 1.

Embodiment 9:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 64g, Pericarpium Citri Reticulatae 37g, Fructus Hordei Germinatus 57g, Semen Arecae 34g, Poria 44g, Radix Paeoniae Alba 24g, Radix Glycyrrhizae 24g, Radix Astragali 54g, Testa Tritici 34g, Semen Armeniacae Amarum 47g, Cortex Magnoliae Officinalis 27g, Radix Sophorae Flavescentis 54g, Semen Raphani 44g.The other the same as in Example 1.

Embodiment 10:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 66g, Pericarpium Citri Reticulatae 38g, Fructus Hordei Germinatus 58g, Semen Arecae 36g, Poria 46g, Radix Paeoniae Alba 26g, Radix Glycyrrhizae 26g, Radix Astragali 56g, Testa Tritici 36g, Semen Armeniacae Amarum 48g, Cortex Magnoliae Officinalis 28g, Radix Sophorae Flavescentis 56g, Semen Raphani 46g.The other the same as in Example 1.

Embodiment 11:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 68g, Pericarpium Citri Reticulatae 39g, Fructus Hordei Germinatus 59g, Semen Arecae 38g, Poria 48g, Radix Paeoniae Alba 28g, Radix Glycyrrhizae 28g, Radix Astragali 58g, Testa Tritici 38g, Semen Armeniacae Amarum 49g, Cortex Magnoliae Officinalis 29g, Radix Sophorae Flavescentis 58g, Semen Raphani 48g.The other the same as in Example 1.

Embodiment 12:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 70g, Pericarpium Citri Reticulatae 40g, Fructus Hordei Germinatus 60g, Semen Arecae 40g, Poria 50g, Radix Paeoniae Alba 30g, Radix Glycyrrhizae 30g, Radix Astragali 60g, Testa Tritici 40g, Semen Armeniacae Amarum 50g, Cortex Magnoliae Officinalis 30g, Radix Sophorae Flavescentis 60g, Semen Raphani 60g.The other the same as in Example 1.

Embodiment 13:

For a Chinese medicine for animal spleen benefiting and stimulating the appetite, be made up of the crude drug of following weight portion: Fructus Crataegi 60g, Pericarpium Citri Reticulatae 35g, Fructus Hordei Germinatus 55g, Semen Arecae 30g, Poria 40g, Radix Paeoniae Alba 20g, Radix Glycyrrhizae 20g, Radix Astragali 50g, Testa Tritici 25g, 45 parts, Semen Armeniacae Amarum, Cortex Magnoliae Officinalis 20g, Radix Sophorae Flavescentis 50g, Semen Raphani 40g.The other the same as in Example 1.

Clinical experimental study

1. pharmacodynamics test

Get local experiment and be divided into 4 groups at random with cattle 40, often organize 10, male and female dual-purpose, adopt the obtained Chinese medicine of embodiment 2 to carry out pharmacodynamics test.(1) blank group; (2) small dose group (300g/ days); (3) dosage group (400g/ days) in; (4) heavy dose of group (600g/ days).Using method: once a day, until recovery from illness.Concrete result of the test is in table 1.

Table 1 results of pharmacodynamic test

Group	Dosage (g/ days)	Experiment cattle (head)	Cure rate (%)	Remarks
					Matched group	0	10	0
Group in a small amount	300	10	90	Administration time is shorter, and total dosage is large
					Middle amount group	400	10	100	The medication phase is short, and total dosage is little
A large amount of groups	600	10	50

As can be seen from experimental result, when the dose of dosage (400g/ days) is treated dyspepsia disease in using, there is good curative effect.

2. the acute poisonous substance test of animal

With each 20 of dose gavage mice of the tolerant Cmax of animal (3g/mL), 0.8mL, male and female half and half, Continuous Observation 7 days, does not find death.Dosage is 120g/kg body weight, is equivalent to 179.1 times of quantity.At viewing duration, do not find that animal has obvious poisoning symptom.

3. long-term toxicity test for animals

Rat Chinese medicine 5g/kg/d and 15g/kg/d (being equivalent to 7.4,22.2 times of clinical administration dosage) continuous four months that gavage embodiment 12 is obtained respectively, general activity, the mental status, hair, feces etc. after two groups of large raticides are showed no obvious abnormalities.Peripheral hemogram before and after administration, comprise erythrocyte, platelet, hemoglobin, packed cell volume all fluctuate within normal range, obvious impact is showed no on three livers (SGPT, SGOT), kidney (blood urea nitrogen, creatinine) functional parameter.During off-test, the content of total protein, albumin, alkali phosphatase no significant difference compared with matched group in animal serum, Electrocardioscopy is and notes abnormalities.Each main organs macroscopy has no the morphological changes of various tissue components such as obvious enlargement, hyperemia, necrosis, the weight coefficient of the heart, liver, spleen, lung, kidney, thymus, adrenal gland, uterus, testis is compared with matched group, without significant difference, histopathologic examination, is showed no exception.These results suggest that Chinese medicine provided by the invention is safer, in tested dosage range, there is no obvious toxic-side effects.(raw data is kept at certain animal and veterinary institute of agriculture and forestry science and technology university).

4. test example

Ten, field, Ba Miao village, Chencang District black-and-white flower animal, main suit: 20 days puerperal of these cattle, slow food 3 days, only eats a small amount of grass, sees refusing to eat after concentrate.In locality with dense salt, the short medicine such as to ruminate, without positive effect.Check normal, a gasterechema is weak, and feces is half congealed rare, includes indigested concentrate slag, sialorrhea, and spirit is depressed.Further inquiring, learn that these cattle premorbids hello concentrate every day is about 13kg, and daily yielding is less than 18kg.So examine the dyspepsia caused for concentrate is excessive.

These ten cattle are divided into two groups at random, often organize five, be respectively matched group and test group, matched group diet, test group feeding adds the Chinese medicine of the obtained spleen benefiting and stimulating the appetite of embodiment 13, and feeding amount is 5g/kg/d.After ten days, the state of an illness of the cattle of matched group is not eased, and the cattle of test group is fully recovered.

Formula of the present invention adopts Chinese medicine completely; with low cost, easy to use, to due to concentrate too much; the symptoms such as the gastrointestinal retention caused, indigestion diarrhea have very satisfied curative effect; used cowboying family of the present invention, all standing in family have this medicine, regularly takes to animal; effectively prevent dyspepsia; the generation of limb hoof disease and four gastropathy, the dark favor by animal cultivation family, the present invention also can be used for the treatment of the same disease of other animal such as pig, chicken.

Above-described is only the preferred embodiment of the present invention, it should be pointed out that for a person skilled in the art, and not departing under general idea prerequisite of the present invention, can also make some changes and improvements, these also should be considered as protection scope of the present invention.

Claims (2)

1. for a Chinese medicine for animal spleen benefiting and stimulating the appetite, it is characterized in that: be made up of the crude drug of following weight portion: Fructus Crataegi 50-70 part, Pericarpium Citri Reticulatae 30-40 part, Fructus Hordei Germinatus 50-60 part, Semen Arecae 20-40 part, Poria 30-50 part, Radix Paeoniae Alba 10-30 part, Radix Glycyrrhizae 10-30 part, Radix Astragali 40-60 part, Testa Tritici 20-35 part, Semen Armeniacae Amarum 40-50 part, Cortex Magnoliae Officinalis 15-30 part, Radix Sophorae Flavescentis 40-60 part, Semen Raphani 30-50 part.

2. a kind of Chinese medicine for animal spleen benefiting and stimulating the appetite according to claim 1, is characterized in that: be made up of the crude drug of following weight portion: Fructus Crataegi 60 parts, Pericarpium Citri Reticulatae 35 parts, 55 parts, Fructus Hordei Germinatus, Semen Arecae 30 parts, 40 parts, Poria, the Radix Paeoniae Alba 20 parts, 20 parts, Radix Glycyrrhizae, the Radix Astragali 50 parts, 25 parts, Testa Tritici, 45 parts, Semen Armeniacae Amarum, Cortex Magnoliae Officinalis 20 parts, Radix Sophorae Flavescentis 50 parts, Semen Raphani 40 parts.