CN103585599A - Veterinary medicine for treating animal digestive tract diseases - Google Patents

Veterinary medicine for treating animal digestive tract diseases Download PDF

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Publication number
CN103585599A
CN103585599A CN201310543483.5A CN201310543483A CN103585599A CN 103585599 A CN103585599 A CN 103585599A CN 201310543483 A CN201310543483 A CN 201310543483A CN 103585599 A CN103585599 A CN 103585599A
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China
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veterinary medicine
radix
parched
digestive tract
pericarpium citri
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CN201310543483.5A
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Chinese (zh)
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不公告发明人
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Qingdao Agricultural University
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Qingdao Agricultural University
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Priority to CN201310543483.5A priority Critical patent/CN103585599A/en
Publication of CN103585599A publication Critical patent/CN103585599A/en
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Abstract

The invention discloses a veterinary medicine for treating animal digestive tract diseases, which is characterized by consisting of the following Chinese herbal medicinal ingredients in part by weight: medicated leaven, roasted malt, stir-fried hawthorn, atractylodes lancea, officinal magnolia bark, dried ginger, liquorice, green tangerine peel, tangerine peel, rhubarb, sophora flavescens and Laimingzi. A preparation method of the veterinary medicine comprises the following steps: after strictly purchasing the traditional Chinese medicine on selection, air-drying or drying; grinding and sieving the powder by an 80-mesh sieve carrying out subpackaging by double-layer plastic bags according to the specification of 500g per bag. The veterinary medicine for treating the animal digestive tract diseases, which is disclosed by the invention, has curative effects of resolving phlegm, clearing away heat, helping digestion and removing accumulation, clearing the hollow viscera, assisting in digesting, eliminating food retention and relieving stagnant qi and relieving intestines and has very satisfied curative effects on gastrointestinal indigestion, food-induced laminitis, impairment and diarrhea which are caused by overeating and the like, which are caused by excessive concentrates. The veterinary medicine also can be used for treating the same symptoms of other animals.

Description

A kind of veterinary drug for animal alimentary canal diseases
Technical field
The invention belongs to tcm field, relate to a kind of veterinary drug, particularly a kind of veterinary drug for animal alimentary canal diseases.
Background technology
The digestive tract disease of animal is one of common disease, in investigation, finds, majority is raised animal field, family scattered, continue to use traditional raising pattern, science raise competence is not high, and especially the quality and quantity of forage grass can not meet the needs of animal, only rely on and increase concentrated feed hello amount, pursue high yield.Result causes the increase of digestive tract disease, has caused the generation of limb hoof disease and metabolic disease (as four gastrokateixias) simultaneously, brings about great losses.The medicine of conventional treatment is according to different diseases: for discharging the front gastric content cathartic of guaranteeing, stop ferment agent, as sodium sulfate, ethanol, ichthyol or Oleum Glycines; For strengthening front gastric peristalsis, tartar emetic acid antimony potassium and Semen Momordicae fourth be can throw, cud massage and pulling motion coordinated simultaneously; When presenting acidosis symptom, can add quiet notes with Fructus Vitis viniferae bran saline, sodium bicarbonate, At; Sometimes also use antibiosis anti-inflammatory drug, as chloromycetin, chlortetracycline, berberine, the pyridine of sulphur ammonia miaow, artificial salt etc.But these medicines are controlled table and are not controlled root, can only solve of short duration pain, can not be to cure in essence.So TCM circle personage, at a kind of Chinese medicine that can treat animal alimentary canal diseases of research, openly used but go back at present nobody.
Summary of the invention
The object of the invention is to provide a kind of veterinary drug for animal alimentary canal diseases, and this medicine can have to the digestive tract disease of animal the effect of obvious treatment.
The object of the invention is to be achieved through the following technical solutions:
For a veterinary drug for animal alimentary canal diseases, it is characterized in that this veterinary drug is comprised of the Chinese medicine ingredients of following weight parts: Massa Medicata Fermentata 50-65g, Fructus Hordei Germinatus (parched) 50-60g, Fructus Crataegi (parched) 50-60g, Rhizoma Atractylodis 45-55g, Cortex Magnoliae Officinalis 10-25g, Rhizoma Zingiberis 10-20g, Radix Glycyrrhizae 15-25g, Pericarpium Citri Reticulatae Viride 15-25g, Pericarpium Citri Reticulatae 20-30g, Radix Et Rhizoma Rhei 15-25g, Radix Sophorae Flavescentis 40-50g, Lay are sprouted sub-30-45g.
Its preparation method is, after above-mentioned Chinese medicine is dried or dried after strictly choosing, to pulverize 80 mesh sieves, by 500 grams of every bags, with double-layer plastic bag packing.
Veterinary drug for animal alimentary canal diseases of the present invention, have reduce phlegm, the curative effect of heat clearing away, food stagnation removing, purging FU-organs, aid digestion, food stagnation, the wide intestinal of dispelling the stagnated QI, to because concentrate is too much, the diseases such as the gastrointestinal retention causing, material wound five are collected together, indigestion diarrhea have very satisfied curative effect.The present invention also can be used for the treatment of the same disease of other animal.
The specific embodiment
The pharmacodynamics test of this veterinary drug providing below in conjunction with inventor and acute and long term toxicity test and specific embodiment are described in further detail the present invention.
1. pharmacodynamics test
Massa Medicata Fermentata, Fructus Hordei Germinatus (parched), Fructus Crataegi in the present invention's formula includes plurality of enzymes, starch, vitamin and thick class, volatilization wet goods material, is one of best compatibility in traditional Chinese medical science removing indigestion prescriptions.And Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Radix Glycyrrhizae, Rhizoma Zingiberis ,Zhe each side Pingwei San; the kind the spleen and stomach being stranded by dampness of being stained with; tripe distention and fullness in the abdomen; stool is warded off and rushes down; stomachache is uneasy waits disease, with Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae Viride, Lay sprout son, to strengthen its invigorating blood circulation tired, the wide intestinal of dispelling the stagnated QI; adjust irritability; reason gastric qi, except distension, the effect of logical stomach internal organs; thereby reach the secretory function of agitating gastral activity and digestive gland; playing reduces phlegm does not help fire, and heat clearing away is impairment of YANG not, and food stagnation removing does not consume gas; purging FU-organs is the curative effect of impairment of body fluid not, Radix Sophorae Flavescentis join the strong gland killing parasites for relieving itching of Rhizoma Atractylodis dampness be aided with again Rhizoma Zingiberis, Radix Glycyrrhizae, with protecting the spleen and stomach, wet in cold expelling.
Following table be matched group, in a small amount group, middle amount group, organize concrete result of the test in a large number:
Group Dosage (g/ days) Experiment cattle (head) Cure rate (%) Remarks
Matched group 0 10 0 ?
A small amount of group 300 10 ? ?
Middle amount group 400 ? 90 Administration time is longer, and total dosage is large
A large amount of groups 500 10 100 The medication phase is short, and total dosage is little
2. animal acute toxicity test
With each 20 of gavage mices of dose of the tolerant Cmax of animal (3g/ml), 0.8ml, male and female half and half, Continuous Observation 7 days, does not occur dead.Dosage is 120g/kg body weight, is equivalent to 179. 1 times of quantity.At viewing duration, do not find that animal has obvious poisoning symptom.
3. long-term toxicity test for animals rat disappear continuous four months of 5g/kg/d, 15 g/kg/d (be equivalent to clinical administration dosage 7.4,22.2 times) of gavage mastitis respectively, general activity after the large raticide of two dosage groups, the mental status, hair, feces etc. are showed no obvious abnormalities.Peripheral hemogram before and after administration, comprises that erythrocyte, platelet, hemoglobin, packed cell volume all fluctuate within normal range.To three livers (SGPT, SGOT), kidney (blood urea nitrogen, flesh are joined) functional parameter is showed no obvious impact.During off-test, in animal serum, the content of total protein, albumin, alkali phosphatase is compared no significant difference with matched group.Electrocardioscopy is all no abnormal.Each main organs macroscopy has no the morphological changes of various tissue components such as obvious enlargement, hyperemia, necrosis.The weight coefficient of the heart, liver, spleen, lung, kidney, thymus, adrenal gland, uterus, testis is compared with matched group, without significant difference.Histopathologic examination, is showed no abnormal.These results suggest that mastitis disappears safer, in trial dosage range, there is no obvious toxic-side effects.(raw data is kept at animal and veterinary institute of Xibei Univ. of Agricultural & Forest Science & Technology).
4. specific embodiment
EXAMPLE l:
This best for the veterinary drug of animal alimentary canal diseases is formulated as: Massa Medicata Fermentata 60g, Fructus Hordei Germinatus (parched) 60g, Fructus Crataegi (parched) 60g, Rhizoma Atractylodis 50g, Cortex Magnoliae Officinalis 20g, Rhizoma Zingiberis 15g, Radix Glycyrrhizae 20g, Pericarpium Citri Reticulatae Viride 20g, Pericarpium Citri Reticulatae 30g, Radix Et Rhizoma Rhei 20g, Radix Sophorae Flavescentis 50g, Lay are sprouted sub-40g.Its preparation method is, after above-mentioned Chinese medicine is dried or dried after strictly choosing, to pulverize 80 mesh sieves, by 500 grams of every bags, with double-layer plastic bag packing.
Embodiment 2:
Being formulated as of this veterinary drug for animal alimentary canal diseases: Massa Medicata Fermentata 55g, Fructus Hordei Germinatus (parched) 55g, Fructus Crataegi (parched) 55g, Rhizoma Atractylodis 45g, Cortex Magnoliae Officinalis 15g, Rhizoma Zingiberis 1Og, Radix Glycyrrhizae 15g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 25g, Radix Et Rhizoma Rhei 15g, Radix Sophorae Flavescentis 45g, Lay are sprouted sub-35g.
Its preparation method is with embodiment 1.
Embodiment 3:
Being formulated as of this veterinary drug for animal alimentary canal diseases: Massa Medicata Fermentata 65g, Fructus Hordei Germinatus (parched) 60g, Fructus Crataegi (parched) 60g, Rhizoma Atractylodis 55g, Cortex Magnoliae Officinalis 25g, Rhizoma Zingiberis 20g, Radix Glycyrrhizae 25g, Pericarpium Citri Reticulatae Viride 25g, Pericarpium Citri Reticulatae 30g, Radix Et Rhizoma Rhei 25g, Radix Sophorae Flavescentis 50g, Lay are sprouted sub-45g.
Its preparation method is with embodiment 1.
If for batch production, can be by the proportional amplification of above-mentioned formula.
Veterinary drug for animal alimentary canal diseases of the present invention is applicable to following symptom: sick cattle appetite, anti-when reducing, rumen peristalsis sound weakens, forage grass can eat a little, especially anorexia concentrate, loose and watery stool is soft, is inside mixed with indigested concentrate slag, tripe abdomen is micro-swollen, after 1 one 2 days, spirit is depressed, and milk amount declines, and the sick cattle sialorrhea having, grinds one's teeth in sleep.
Using method: each 500g is for oral administration, once a day, until recovery from illness.
Concrete case: a certain 5 years old black-and-white flower animal in field, Ba Miao village, Chencang District, main suit: in 20 days puerperal of this cattle, eat slowly oneself 3 days, only eat a small amount of grass, see refusing to eat after concentrate.In locality with dense salt, the short medicine such as ruminate, without positive effect.Check that normally a little less than a gasterechema, feces is half congealed rare, includes indigested concentrate slag, sialorrhea, spirit is depressed.Further inquiring, learns this cattle premorbid hello about 13kg of concentrate every day, and the not enough 18kg of daily yielding.So examine the dyspepsia causing for concentrate is excessive.With bent wheat loose 3 bags that help digestion, recovery from illness subsequently.
Formula of the present invention adopts Chinese medicine completely; with low cost, easy to use, to because concentrate is too much; the diseases such as the gastrointestinal retention causing, material wound five are collected together, indigestion diarrhea have very satisfied curative effect; used cowboying of the present invention family, all standing in family have this medicine, regularly to animal, takes; effectively prevented dyspepsia; the generation of limb hoof disease and four gastropathy, is subject to the favor at animal cultivation family deeply, and the present invention also can be used for the treatment of the same disease of other animal.

Claims (2)

1. for a veterinary drug for animal alimentary canal diseases, it is characterized in that this veterinary drug is comprised of the Chinese medicine ingredients of following weight parts: Massa Medicata Fermentata 50 ~ 65g, Fructus Hordei Germinatus (parched) 50 ~ 60g, Fructus Crataegi (parched) 50 ~ 60g, Rhizoma Atractylodis 45 ~ 55g, Cortex Magnoliae Officinalis 10 ~ 25g, Rhizoma Zingiberis 10 ~ 20g, Radix Glycyrrhizae 15 ~ 25g, Pericarpium Citri Reticulatae Viride 15 ~ 25g, Pericarpium Citri Reticulatae 20 ~ 30g, Radix Et Rhizoma Rhei 15 ~ 25g, Radix Sophorae Flavescentis 40 ~ 50g, Lay are sprouted son 30 ~ 45g.
2. the veterinary drug for animal alimentary canal diseases as claimed in claim 1, it is characterized in that this Chinese patent medicine is comprised of the Chinese medicine ingredients of following weight parts: Massa Medicata Fermentata 60g, Fructus Hordei Germinatus (parched) 60g, Fructus Crataegi (parched) 60g, Rhizoma Atractylodis 50g, Cortex Magnoliae Officinalis 20g, Rhizoma Zingiberis 15g, Radix Glycyrrhizae 20g, Pericarpium Citri Reticulatae Viride 20g, Pericarpium Citri Reticulatae 30g, Radix Et Rhizoma Rhei 20g, Radix Sophorae Flavescentis 50g, Lay are sprouted sub-40g.
CN201310543483.5A 2013-11-06 2013-11-06 Veterinary medicine for treating animal digestive tract diseases Pending CN103585599A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104127487A (en) * 2014-07-28 2014-11-05 山东省动物疫病预防与控制中心 Drug for treating mink digestive tract diseases
CN106490366A (en) * 2016-11-01 2017-03-15 登封市老拴保肥料有限公司 A kind of for whetting appetite, the pig feed additive of diseases prevention
CN106819436A (en) * 2017-01-23 2017-06-13 长治市雄丰清真养殖屠宰有限公司 A kind of fodder compound of prevention cattle and sheep taeniasis
CN107050409A (en) * 2017-03-10 2017-08-18 天津市畜牧兽医研究所 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104127487A (en) * 2014-07-28 2014-11-05 山东省动物疫病预防与控制中心 Drug for treating mink digestive tract diseases
CN106490366A (en) * 2016-11-01 2017-03-15 登封市老拴保肥料有限公司 A kind of for whetting appetite, the pig feed additive of diseases prevention
CN106819436A (en) * 2017-01-23 2017-06-13 长治市雄丰清真养殖屠宰有限公司 A kind of fodder compound of prevention cattle and sheep taeniasis
CN107050409A (en) * 2017-03-10 2017-08-18 天津市畜牧兽医研究所 A kind of herbal composite for adjusting intestine of young pigs health and preparation method and application

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Application publication date: 20140219