CN104522006A - Composition for preventing and controlling lepidoptera and homopteran pests - Google Patents
Composition for preventing and controlling lepidoptera and homopteran pests Download PDFInfo
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Abstract
The invention discloses an insecticidal composition containing two effective components including HNPC-A8008 and abamectin, wherein the weight ratio of the effective components, namely HNPC-A8008 to abamectin is 1:100 to 100:1, and the weight sum of HNPC-A8008 and abamectin accounts for 10-70% of the weight percentage of the composition. Proved by a great number of indoor and outdoor experiments, The composition disclosed by the invention has the advantages that a remarkable synergistic effect is achieved after HNPC-A8008 and abamectin are mixed, so that the application field of HNPC-A8008 is widened in actual application, the pesticide-resistant risks of pests to abamectin are reduced, and the aims of taking a combined effect on the pests on multiple aspects, widening the prevented and controlled object range, improving the preventing and controlling effects, effectively preventing and controlling lepidoptera and homopteran pests on vegetables, rice, fruit trees and flower crops, and meanwhile reducing the dosage of a pesticide in a field, agricultural cost and environment pollution caused by the pesticide are achieved.
Description
Technical field
The present invention relates to a kind of Pesticidal combination; contained active ingredient is (E)-5-(3-chlorallyl) amino-1-(2; 6-dichlor-4-trifluoromethyl) phenyl-4-trifluoromethyl sulfinyl pyrazole-3-nitrile (test code number is HNPC-A8008) and Avermectin, for preventing and treating Lepidoptera and homoptera pest.
Background technology
Chemical name is (E)-5-(3-chlorallyl) amino-1-(2; 6-dichlor-4-trifluoromethyl) compound (test code number is HNPC-A8008) of phenyl-4-trifluoromethyl sulfinyl pyrazole-3-nitrile; that Hunan Chemical Research Institute is in order to reduce the fat-soluble of ethiprole medicament; by the new pyrazole compound with insecticidal activity of modifying for chemical structure design and synthesis, new chemical constitution improves the adverse side effect of this compounds to non-target organism.Formula 1 be shown in the chemical structural formula of HNPC-A8008.
HNPC-A8008 can be used for the control of the various crop insects such as paddy rice, vegetables, cotton, beet, as beet armyworm, prodenia litura, striped rice borer, paddy stem borer, rice leaf roller, cabbage caterpillar, aphid etc., its mode of action is based on stomach toxicity, there is certain contact toxicity, systemic activity is more weak, and quick-acting is good; This medicament is mainly used in numerous coleopteran pest control such as paddy rice, fruit tree, vegetables.
Avermectin (abamectin, A) is the natural products be separated from edaphon, is a kind of farm antibiotics, and its main mode of action is tagged, and stomach toxicity, penetration is strong.It is a kind of macrolide disaccharide compounds.Formula 2 be shown in Avermectin chemical structural formula.
Avermectin has insects and mites tags and stomach poison function have faint fumigation action, without systemic action.Its mechanism of action and general insecticide disturb neurophysiology movable unlike it, stimulate release r-aminobutyric acid, and r-aminobutyric acid has inhibitory action to arthropodan nerve conduction, if namely there is paralysis symptom after becoming mite to contact with medicament with larva with insect in mite class, inertia does not take food, dead after 2-4 days.But it has very strong osmosis to blade, subepidermal insect can be killed, and the longevity of residure is long.Simultaneously because consumption is little, easily degrade, thus environmentally safe, noresidue.To plant height safety.In a word, Avermectin is a kind of efficient, high selection, green, environment-friendly type, biological source insecticide.Avermectin has good effect for preventing and treating the insects such as striped rice borer, paddy stem borer, rice leaf roller, cotton bollworm, smaller green leaf hopper in recent years, but quick-acting is slightly poor, and Long-Time Service, insect creates resistance to it.
The two uses with proper proportion mixture, can from many aspects to insect synergy, and reaching just can the effective object that causes harm of Control pests with lower dosage.Dosage reduces simultaneously, also alleviates the pressure of chemical pesticide to environment, can also delay the generation of pest resistance to insecticide.Therefore, Avermectin and HNPC-A8008 mixture are worthy of popularization in agricultural production.
Not yet there is the report of HNPC-A8008 and Avermectin mixture at present.
Summary of the invention
The object of the invention is to reduce the anti-medicine risk of insect to Avermectin, widen the use field of HNPC-A8008, reach from many aspects to insect acting in conjunction, expanding prevention object, improve control efficiency, effective pest control, reduce the using dosage of medicament in field simultaneously, reduce agricultural cost, reduce medicament to the object of the pollution of environment, a kind of Pesticidal combination is provided, contained active ingredient is chemical name is (E)-5-(3-chlorallyl) amino-1-(2, 6-dichlor-4-trifluoromethyl) HNPC-A8008 of phenyl-4-trifluoromethyl sulfinyl pyrazole-3-nitrile and Avermectin, the chemical structural formula of HNPC-A8008 is:
The formulation of Pesticidal combination of the present invention comprises microemulsion or aqueous emulsion, suspending agent, wetting powder, water dispersible granules.
The weight proportion of active ingredient HNPC-A8008 of the present invention and Avermectin is that the weight sum of 1:100 ~ 100:1, HNPC-A8008 and Avermectin accounts for 10% ~ 70% of composition total weight percentage.
When the formulation of Pesticidal combination is microemulsion, the weight percentage of each component is: HNPC-A8008 0.1 ~ 20%; Avermectin 0.1 ~ 20%; Solvent 10 ~ 30%; Emulsifier 5 ~ 30%; Antifreezing agent 1 ~ 5%; Stabilizing agent 1 ~ 10%; Deionized water adds to 100%;
When the formulation of Pesticidal combination is aqueous emulsion, the weight percentage of each component is: HNPC-A8008 0.1 ~ 25%; Avermectin 0.1 ~ 25%; Emulsifier 5 ~ 25%; Solvent 5 ~ 15%; Stabilizing agent 1 ~ 10%; Antifreezing agent 1 ~ 5%; Thickener 0.1 ~ 2%; Deionized water adds to 100%;
When the formulation of Pesticidal combination is suspending agent, the weight percentage of each component is HNPC-A8008 0.1 ~ 20%; Avermectin 0.1 ~ 20%; Solvent 5 ~ 20%; Emulsifier 5 ~ 20%; Wetting agent 1 ~ 10%; Dispersant 1 ~ 10%; Antifreezing agent 1 ~ 5%; Thickener 0.1 ~ 2%; Defoamer 0.1 ~ 1%; Deionized water adds to 100%.
When the formulation of Pesticidal combination is wetting powder, the weight percentage of each component is: HNPC-A8008 10 ~ 60%; Avermectin 10 ~ 60%; Dispersant 5 ~ 10%; Wetting agent 5 ~ 10%; Filler adds to 100%;
When the formulation of Pesticidal combination is water dispersible granules, the weight percentage of each component is: HNPC-A8008 5 ~ 65%; Avermectin 5 ~ 65%; Dispersant 5 ~ 15%; Wetting agent 5 ~ 10%; Disintegrant 1 ~ 8%; Filler adds to 100%;
Described solvent comprises the mixing of one or more in deionized water, methyl alcohol, ethanol, butanols, propane diols, glycerine, polyethylene glycol, cyclohexanone, pyrrolidones, ethyl acetate;
Described emulsifier comprises agriculture breast 500
#i.e. alkyl benzene calcium sulfonate, agriculture breast 400
#i.e. benzyl dimethyl phenol polyoxyethyl ether, Nongru-700
#i.e. alkylphenol-formaldehyde resin polyoxyethyl ether, agriculture breast 1600
#namely one or several the mixing in phenethyl phenol polyoxyethanyl polypropylene-base ether, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, ethylene oxide-propylene oxide block copolymer, OP series and polyoxyethylene nonylphenol ether, BY series and castor oil polyoxyethylene ether, Span series and sorbitol anhydride monostearate, TWEEN Series and anhydrous sorbitol fat acid ester polyoxyethylene ether, AEO series and fatty alcohol-polyoxyethylene ether;
It is one or more mixing in glycerine, propane diols, diethylene glycol (DEG), polyethylene glycol etc. that described antifreezing agent comprises;
Described stabilizing agent comprises the mixing of one or more in xylitol, mannitol, pentaerythrite, triphenyl phosphite, sodium citrate etc.;
Described thickener comprises the mixing of one or more in polyvinyl alcohol, polyvinyl acetate, xanthans, gelatin, gum Arabic, polyvinylpyrrolidone, aluminium-magnesium silicate, phenolic resins, CMC, sodium alginate etc.;
Described defoamer comprises silicone oil, silicone compound, C
10-20saturated fat acid compounds, C
8-10the mixing of one or more of fatty alcohol;
Described wetting agent comprises the mixing of one or more in lauryl sodium sulfate, neopelex, sodium butylnaphthalenesulfonate, petroleum sodium sulfonate, wetting and penetrating agent F, Nekal BX, the withered powder of tea, spaonin powder, soapberry powder;
Described dispersant comprises the mixing of one or more in lignosulfonates, polycarboxylate, alkylphenol polyoxyethylene sulphate, alkyl benzene sulfonate calcium salt, fatty acid ester sulphate, alkylphenol polyoxyethylene, sodium metnylene bis-naphthalene sulfonate, fatty alcohol-polyoxyethylene ether etc.;
Described filler comprises the mixing of one or more in precipitated calcium carbonate, potter's clay, kaolin, diatomite, bentonite, white carbon, talcum powder, quartz sand etc.;
Described disintegrant comprises the mixing of one or more in sodium bicarbonate, magnesium chloride, aluminium chloride, sodium chloride, urea, ammonium sulfate, bentonite etc.
The present composition shows through a large amount of indoor and outdoor tests, HNPC-A8008 and Avermectin mixture have obvious synergistic function, the use field of HNPC-A8008 has been widened when practical application, reduce insect to the anti-medicine risk of Avermectin, reach from many aspects to insect acting in conjunction, expanding prevention object, improve control efficiency, effectively prevent and treat vegetables, paddy rice, the Lepidoptera of fruit tree and flower crop and homoptera pest, reduce the using dosage of medicament in field simultaneously, reduce agricultural cost, reduce medicament to the object of the pollution of environment.
Embodiment
In order to understand essence of the present invention better, below in conjunction with embodiment, the invention will be further described, but be never limited to following embodiment.Content mentioned in embodiment is not limitation of the invention, and in preparation method, the selection of the process conditions such as temperature, time can be suited measures to local conditions and there is no substantial effect to result.Embodiment each component proportioning is all weight percentage.
Embodiment 1:10.1%HNPC-A8008 Avermectin suspending agent.
When suspending agent is processed in the present invention, the weight percentage of each component is: HNPC-A8008 0.1%; Avermectin 10%; Emulsifier: BY-1405%, polyoxyethylene nonylphenol ether 8%; Solvent: cyclohexanone 5%, methyl alcohol 8%; Wetting agent: sodium butylnaphthalenesulfonate: 3%; Dispersant alkyl benzene calcium sulfonate: 3%; Antifreezing agent: propane diols 1%; Thickener: xanthans 0.1%; Defoamer organosilicon: 0.1%; Deionized water adds to 100%.The concrete production stage of this suspending agent is: first the said components except active ingredient mixed, mix through high speed shear, then active ingredient HNPC-A8008 and Avermectin is added, grind 2 ~ 3 hours in ball crusher, make diameter of particle all below 5 μm, namely make the aqueous suspension formulations of the present composition.
Embodiment 2:10.1%HNPC-A8008 abamectin aqueous emulsion
When aqueous emulsion is processed in the present invention, the weight percentage of each component is: HNPC-A8008 10%; Avermectin 0.1%; Emulsifier agriculture breast 500
#8%, polyoxyethylene nonylphenol ether 5%; Solvent: cyclohexanone 6%, methyl alcohol 7%; ; Stabilizing agent: sodium citrate 1%; Antifreezing agent: propane diols 1%; Thickener: xanthans 0.1%; Deionized water adds to 100%.The concrete production stage of this aqueous emulsion is: first HNPC-A8008 and Avermectin, solvent and emulsifier are added together, and makes to be dissolved into uniform oil phase; Then other the auxiliary agent such as portions of de-ionized water, stabilizing agent is mixed uniformly aqueous phase; Then oil phase is added aqueous phase while high-speed stirred in a kettle., slowly add water until reach phase inversion point, open clipper and carry out high speed shear, and add remaining deionized water, shear about half an hour, form the aqueous emulsion of oil-in-water type, namely can be made into the aqueous emulsion preparation of the present composition.
Embodiment 3:10%HNPC-A8008 avermectin micro-emulsion
When microemulsion is processed in the present invention, the weight percentage of each component is: HNPC-A8008 7%; Avermectin 3%; Solvent: cyclohexanone 5%, methyl alcohol 8%; Emulsifier: alkyl benzene calcium sulfonate 5%, benzyl dimethyl phenol polyoxyethyl ether 7%; Antifreezing agent: propane diols 1%; Stabilizing agent: sodium citrate 1%; Deionized water adds to 100%.The concrete production stage of this microemulsion is: first HNPC-A8008 and Avermectin solvent are dissolved completely, then adds other auxiliary agents such as emulsifier, antifreezing agent, is uniformly mixed being uniformly mixed in still, namely can be made into the microemulsion formulation of the present composition.
Embodiment 4:70%HNPC-A8008 Avermectin wetting powder
When the present invention is wetting powder, the weight percentage of each component is: HNPC-A8008 60%; Avermectin 10%; Dispersant: lignosulfonates 8%; Wetting agent: Nekal BX 8%; Filler: talcum powder 6%; Kaolin adds to 100%.The concrete production stage of this wetting powder is: mixed with Avermectin and dispersant, wetting agent and filler by active ingredient HNPC-A8008, again through air-flow crushing after mechanical crushing, mixes, and namely can be made into the wettable powder formulation of the present composition.Active ingredient HNPC-A8008 is mixed with Avermectin and dispersant, wetting agent and filler, again through air-flow crushing after mechanical crushing, mixes, namely can be made into the wettable powder formulation of the present composition.
Embodiment 5:25%HNPC-A8008 Avermectin water dispersible granules
When the present invention is water dispersible granules, the weight percentage of each component is: HNPC-A8008 20%; Avermectin 5%; Dispersant: calcium salt of dodecylbenzene sulfonate 10%; Wetting agent: wetting and penetrating agent F 8%; Disintegrant: sodium chloride 2%; Filler quartz sand 5%; Kaolin adds to 100%.The concrete production stage of this water dispersible granules is: mixed with Avermectin and dispersant, wetting agent, disintegrant and filler by active ingredient HNPC-A8008 by above-mentioned formula, pulverize with micro jet, through mediating, then add in fluidized-bed granulation dryer and to carry out after granulation, drying, screening, through sample analysis, namely can be made into the water-dispersible grain agent formulation of the present composition.
Described wetting agent is the mixing of one or more in lauryl sodium sulfate, neopelex, sodium butylnaphthalenesulfonate, petroleum sodium sulfonate, wetting and penetrating agent F, Nekal BX, the withered powder of tea, spaonin powder, soapberry powder etc.
Described dispersant is the mixing of one or more in lignosulfonates, polycarboxylate, alkylphenol polyoxyethylene sulphate, alkyl benzene sulfonate calcium salt, fatty acid ester sulphate, alkylphenol polyoxyethylene, fatty alcohol-polyoxyethylene ether etc.
Described antifreezing agent is one or more mixing in glycerine, propane diols, diethylene glycol (DEG), polyethylene glycol etc.
Described thickener is the mixing of one or more in polyvinyl alcohol, polyvinyl acetate, xanthans, gelatin, gum Arabic, polyvinylpyrrolidone, aluminium-magnesium silicate, phenolic resins, CMC, sodium alginate etc.
Described defoamer is selected from silicone oil, silicone compound, C
10-20saturated fat acid compounds, C
8-10the mixing of one or more of fatty alcohol.
Described solvent is the mixing of one or more in deionized water, methyl alcohol, ethanol, butanols, propane diols, glycerine, polyethylene glycol, cyclohexanone, pyrrolidones, ethyl acetate.
Described emulsifier is agriculture breast 500
#(alkyl benzene calcium sulfonate), agriculture breast 400
#(benzyl dimethyl phenol polyoxyethyl ether), Nongru-700
#(alkylphenol-formaldehyde resin polyoxyethyl ether), agriculture breast 1600
#(phenethyl phenol polyoxyethanyl polypropylene-base ether), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), BY series (castor oil polyoxyethylene ether), Span series (sorbitol anhydride monostearate), one or several mixing in TWEEN Series (anhydrous sorbitol fat acid ester polyoxyethylene ether) or AEO series (fatty alcohol-polyoxyethylene ether).
The mixing of one or more in described stabilizing agent xylitol, mannitol, pentaerythrite, triphenyl phosphite, sodium citrate etc.
Described filler is the mixing of one or more in precipitated calcium carbonate, potter's clay, kaolin, diatomite, bentonite, white carbon, talcum powder, quartz sand etc.
Described disintegrant is the mixing of one or more in sodium bicarbonate, magnesium chloride, aluminium chloride, sodium chloride, urea, ammonium sulfate, bentonite etc.
Pesticidal combination provided by the invention, have efficiently, wide spectrum, low toxicity, quick-acting are good and the lasting period is long, insect is not easy to develop immunity to drugs, to features such as crop safeties.The method of usual employing routine spraying uses, and also can adopt other operation techniques agriculturally applied as required.Such as conventional Pesticide use method: spray-on process, bait method, seed treatment, seed pelleting method, soil treatment method, semar technique etc.
Pesticidal combination provided by the invention, should note in insect egg hatching peak period to the medication of low instar larvae phase when applying, now insect resistance is more weak has easily given play to best drug effect.
The present invention has following characteristics:
1. composition pesticide provided by the invention, obvious synergistic effect is shown in certain ratio range, the control efficiency of composition is significantly improved than single dose, reduces the using dosage of agricultural chemicals, dispenser recruitment and cost simultaneously, decreases the impact on environment and residue of pesticide.To insect, there is obvious synergy killing action, and can overcome and delay the generation of pest resistance to insecticide; 2. overcome the limitation that single chemical control spectrum is narrower, expand control spectrum, a dispenser can prevent and treat simultaneous various pests.Effectively can prevent and treat vegetables, paddy rice, cotton, the Lepidoptera of fruit tree and flowers and other crops and homoptera pest.
3. be the excellent substitute kind of high-toxic pesticide.When every mu of effective ingredient consumption is 1 ~ 8g, rice grub (comprising the insects such as striped rice borer, paddy stem borer, rice leaf roller) and vegetable-crop pest-insect (comprising prodenia litura, beet armyworm, diamond-back moth, cabbage caterpillar, aphid, aleyrodid, thrips) effectively can be killed.
Embodiment
In order to understand essence of the present invention better, below in conjunction with embodiment, the invention will be further described, but be never limited to following embodiment.
Embodiment 6: co-toxicity coefficient method (CTC) is screened: HNPC-A8008 and abamectin compounded to diamond-back moth joint toxicity measuring.
For examination target: the diamond-back moth third-instar larvae that indoor for many generations raising Individual Size is consistent with physiological status.
The former medicine of reagent agent: 95%HNPC-A8008 and the former medicine of 95% Avermectin.
Test method: survey standard method NY/T1154.14-2008 with reference to raw, adopts leaching leaf dish method.Reagent agent is made into certain density mother liquor, then it is stand-by to be diluted to 6 concentration with clear water, if clear water is contrast.With the card punch of diameter 18mm, cabbage is broken into leaf dish, by leaf dish after supplying to flood 10 seconds in reagent liquid, put into the culture dish (diameter 90mm) being lined with moisturizing filter paper, 5 leaf dish put into by every ware, after naturally drying, diamond-back moth 3 instar larvae having selected 4h more hungry is in culture dish, every ware is not less than 10, repeat for 4 times, be disposed, cover ware lid, be placed in observation ward and cultivate, routine observation, inspection record death condition after 72hr, calculate lethality (%), and obtain virulence regression equation formula according to probit analysis, correlation coefficient (r) and lethal middle trial (LC
50).Co-toxicity coefficient method (CTC) method adopting Sun & Johnson (1960) to propose evaluates synergy.Usually, co-toxicity coefficient is greater than 120 expression synergistic effects, and be less than 80 for antagonism, be summation action between 80 ~ 120.Co-toxicity coefficient computing formula is as follows:
The percentage (%) of toxicity index × B medicament shared by mixture of percentage (the %)+medicament B of toxicity index × A medicament shared by mixture of theoretical toxicity index (the TTI)=medicament A of mixture
HNPC-A8008, Avermectin and the two toxicity test of ratio mixture to diamond-back moth of 1: 1,1: 30,1: 70,1: 100,30: 1,70: 1 and 100: 1 the results are shown in Table 1.Result shows, HNPC-A8008 and Avermectin are carried out mixture with above-mentioned 7 ratios and shown as obvious synergistic effect to diamond-back moth, its LC
50value is respectively 0.66,0.48,0.52,0.59,1.36,1.66 and 2.04mg/L, and co-toxicity coefficient is respectively 177.10,161.99,147.61,129.71,173.03,147.57 and 121.22.
Table 1, HNPC-A8008 and Avermectin and different ratio are to the toxicity test (72h) of wild cabbage diamond-back moth
Embodiment 7: co-toxicity coefficient method (CTC) is screened: HNPC-A8008 and the abamectin compounded joint toxicity measuring to striped rice borer.
Survey standard method NY/T1154.4-2006 with reference to raw, adopt infusion process.Reagent agent is made into certain density mother liquor, then it is stand-by to be diluted to 6 concentration with clear water, if clear water is contrast.The fresh and tender rice stem of clip floods 10s in for reagent liquid, and take out and be put in ready teat glass, often 4 sections of rice stems put into by pipe, naturally dry, in test tube, then access striped rice borer 3 instar larvae 10, mouth of pipe gauze is tightened, often process and repeat for 4 times, be disposed to be placed in observation ward and cultivate.Routine observation, inspection record death condition after 72hr, calculates lethality (%), and obtains virulence regression equation formula, correlation coefficient (r) and lethal middle trial (LC according to probit analysis
50).Co-toxicity coefficient method (CTC) method adopting Sun & Johnson (1960) to propose evaluates synergy.Usually, co-toxicity coefficient is greater than 120 expression synergistic effects, and be less than 80 for antagonism, be summation action between 80 ~ 120.Co-toxicity coefficient computing formula is as follows:
The percentage (%) of toxicity index × B medicament shared by mixture of percentage (the %)+medicament B of toxicity index × A medicament shared by mixture of theoretical toxicity index (the TTI)=medicament A of mixture
HNPC-A8008, Avermectin and the two toxicity test of ratio mixture to striped rice borer of 1: 1,1: 30,1: 70,1: 100,30: 1,70: 1 and 100: 1 the results are shown in Table 2.From table, HNPC-A8008 and Avermectin are carried out mixture with above-mentioned 7 ratios and are all shown as obvious synergistic effect to striped rice borer, its LC
50value is respectively 0.99,1.82,1.98,2.26,0.76,0.85 and 0.90mg/L, and co-toxicity coefficient is respectively 174.81,153.63,144.67,127.47,164.92,145.89 and 137.45.
Table 2, HNPC-A8008 and Avermectin and different ratio are to the toxicity test (72h) of striped rice borer
Embodiment 8: co-toxicity coefficient method (CTC) is screened: HNPC-A8008 and the abamectin compounded joint toxicity measuring to orange caterpillar.
With reference to the method in NY/T1154.13-2008 standard, adopt leaf disc spray.Choose the Citrus leaf that growth is consistent, make leaf dish with the card punch of diameter 18mm, in culture dish, place a wet sponge block, it puts filter paper, foliation dish on filter paper, every ware three leaf dish, be inoculated on leaf dish with the orange caterpillar that writing brush picking Individual Size is consistent, 10 ~ 15, every leaf dish.By the adjustment of the atomisation pressure of Potter spray tower 1.47 × 10
5the stable state of Pa, first cleans 2 times with acetone by clean fog-spray nozzle, is cleaning 2 times with distilled water.Culture dish is placed in Potter spray tower chassis to spray, spray amount 1ml, take out after liquid sedimentation 1min, then ware mouth is sealed with preservative film, and the ventilation of some apertures is pricked with syringe needle on film, often process and repeat for 4 times, and establish the process not containing medicament (containing solvent for use and emulsifier) not make blank.Be disposed under being transferred to rearing conditions and raise.。Inspection record death condition after 48h, calculates lethality (%), and obtains virulence regression equation formula, correlation coefficient (r) and lethal middle trial (LC according to probit analysis
50).Co-toxicity coefficient method (CTC) method adopting Sun & Johnson (1960) to propose evaluates synergy.Usually, co-toxicity coefficient is greater than 120 expression synergistic effects, and be less than 80 for antagonism, be summation action between 80 ~ 120.Co-toxicity coefficient computing formula is as follows:
The percentage (%) of toxicity index × B medicament shared by mixture of percentage (the %)+medicament B of toxicity index × A medicament shared by mixture of theoretical toxicity index (the TTI)=medicament A of mixture
HNPC-A8008, Avermectin and the two toxicity test of ratio mixture to orange caterpillar of 1: 1,1: 40,1: 70,1: 100,40: 1,70: 1 and 100: 1 the results are shown in Table 3.From table, HNPC-A8008 and Avermectin are carried out mixture with above-mentioned 7 ratios and are all shown as obvious synergistic effect to striped rice borer, its LC
50value is respectively 0.50,0.55,0.49,0.51,0.82,0.70 and 0.9m2g/L, and co-toxicity coefficient is respectively 176.75,130.34,145.70,139.76,140.47,165.64 and 126.37.
Table 3, HNPC-A8008 and Avermectin and different ratio are to the toxicity test (48h) of orange caterpillar
Embodiment 9:HNPC-A8008 and Avermectin mixture composition are to the field control effectiveness test of wild cabbage diamond-back moth.
Reagent agent: (1) 25%HNPC-A8008 Avermectin suspending agent (HNPC-A8008 15%: Avermectin 10%); 2) 15%HNPC-A8008 abamectin aqueous emulsion (HNPC-A8008 10%: Avermectin 5%).
Contrast medicament: (1) 10%HNPC-A8008 suspending agent; (2) 10% Avermectin suspending agents.
Spraying time: be watered even spraying in the wild cabbage diamond-back moth low instar larvae phase.
Result of the test: in table 4.As can be seen from the test results, after dispenser 1 day, composition pesticide of the present invention was to little dose of wild cabbage; Execute the control efficiency of diamond-back moth all more than 70%, significantly better than after single medicine 3 days, 7 days and 14 days, composition pesticide of the present invention to the control efficiency of wild cabbage diamond-back moth all more than 80%, also significantly single dose is better than, illustrate that Pesticidal combination of the present invention is all better than single dose in quick-acting and lasting effect, and cost reduces greatly.
The field control effectiveness test result of table 4, each process chemical control wild cabbage diamond-back moth
Embodiment 10:HNPC-A8008 and Avermectin mixture composition are to the field control effectiveness test of striped rice borer.
Reagent agent: (1) 15%HNPC-A8008 Avermectin suspending agent (HNPC-A8008 7%, Avermectin 8%).
(2) 20%HNPC-A8008 Avermectin wetting powder (HNPC-A8008 15%, Avermectin 5%).
Contrast medicament: (1) 10%HNPC-A8008 suspending agent; (2) 3% Avermectin wetting powders.
Spraying time: be watered even spraying in striped rice borer egg hatching peak period.
Result of the test: in table 5.As can be seen from the test results, after dispenser 14 days, Pesticidal combination of the present invention to the control efficiency of striped rice borer all more than 80%, significantly better than single dose, illustrate that Pesticidal combination of the present invention is all better than single dose in quick-acting and lasting effect, and cost reduces greatly.
The field control effectiveness test result of table 5, water prevention chilo suppressalis
Embodiment 11:HNPC-A8008 and Avermectin mixture composition are to the field control effectiveness test of orange caterpillar.
Reagent agent: (1) 25%HNPC-A8008 Avermectin water dispersible granules (HNPC-A8008 20%: Avermectin 5%); 2) 15%HNPC-A8008 abamectin aqueous emulsion (HNPC-A8008 10%: Avermectin 5%).
Contrast medicament: (1) 10%HNPC-A8008 suspending agent; (2) 10% Avermectin suspending agents.
Spraying time: be watered even spraying at orange caterpillar occurrence in peak period.
Result of the test: in table 6.As can be seen from the test results, after dispenser 1 day, composition pesticide of the present invention to the control efficiency of orange caterpillar all more than 70%, significantly better than after single medicine 3 days, 7 days and 14 days, composition pesticide of the present invention to the control efficiency of wild cabbage diamond-back moth all more than 80%, also be significantly better than single dose, illustrate that Pesticidal combination of the present invention is all better than single dose in quick-acting and lasting effect, and cost reduce greatly.
The field control effectiveness test result of table 6, each process chemical control orange caterpillar
Claims (3)
1. a control Lepidoptera and homoptera pest composition; it is characterized in that insecticidal active ingredient be chemical name is (E)-5-(3-chlorallyl) amino-1-(2; 6-dichlor-4-trifluoromethyl) HNPC-A8008 of phenyl-4-trifluoromethyl sulfinyl pyrazole-3-nitrile and Avermectin, the chemical structural formula of HNPC-A8008 is:
Wherein the weight proportion of HNPC-A8008 and Avermectin is 1:100 ~ 100:1, the weight sum of HNPC-A8008 and Avermectin accounts for 10% ~ 70% of composition total weight percentage, and the formulation of Pesticidal combination comprises microemulsion or aqueous emulsion, suspending agent, wetting powder, water dispersible granules.
2. Pesticidal combination according to claim 1, is characterized in that:
When the formulation of Pesticidal combination is microemulsion, the weight percentage of each component is: HNPC-A80080.1 ~ 20%; Avermectin 0.1 ~ 20%; Solvent 10 ~ 30%; Emulsifier 5 ~ 30%; Antifreezing agent 1 ~ 5%; Stabilizing agent 1 ~ 10%; Deionized water adds to 100%;
When the formulation of Pesticidal combination is aqueous emulsion, the weight percentage of each component is: HNPC-A80080.1 ~ 25%; Avermectin 0.1 ~ 25%; Emulsifier 5 ~ 25%; Solvent 5 ~ 15%; Stabilizing agent 1 ~ 10%; Antifreezing agent 1 ~ 5%; Thickener 0.1 ~ 2%; Deionized water adds to 100%;
When the formulation of Pesticidal combination is suspending agent, the weight percentage of each component is HNPC-A80080.1 ~ 20%; Avermectin 0.1 ~ 20%; Solvent 5 ~ 20%; Emulsifier 5 ~ 20%; Wetting agent 1 ~ 10%; Dispersant 1 ~ 10%; Antifreezing agent 1 ~ 5%; Thickener 0.1 ~ 2%; Defoamer 0.1 ~ 1%; Deionized water adds to 100%.
When the formulation of Pesticidal combination is wetting powder, the weight percentage of each component is: HNPC-A800810 ~ 60%; Avermectin 10 ~ 60%; Dispersant 5 ~ 10%; Wetting agent 5 ~ 10%; Filler adds to 100%;
When the formulation of Pesticidal combination is water dispersible granules, the weight percentage of each component is: HNPC-A80085 ~ 65%; Avermectin 5 ~ 65%; Dispersant 5 ~ 15%; Wetting agent 5 ~ 10%; Disintegrant 1 ~ 8%; Filler adds to 100%;
Described solvent comprises the mixing of one or more in deionized water, methyl alcohol, ethanol, butanols, propane diols, glycerine, polyethylene glycol, cyclohexanone, pyrrolidones, ethyl acetate;
Described emulsifier comprises agriculture breast 500
#i.e. alkyl benzene calcium sulfonate, agriculture breast 400
#i.e. benzyl dimethyl phenol polyoxyethyl ether, Nongru-700
#i.e. alkylphenol-formaldehyde resin polyoxyethyl ether, agriculture breast 1600
#namely one or several the mixing in phenethyl phenol polyoxyethanyl polypropylene-base ether, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, ethylene oxide-propylene oxide block copolymer, OP series and polyoxyethylene nonylphenol ether, BY series and castor oil polyoxyethylene ether, Span series and sorbitol anhydride monostearate, TWEEN Series and anhydrous sorbitol fat acid ester polyoxyethylene ether, AEO series and fatty alcohol-polyoxyethylene ether;
It is one or more mixing in glycerine, propane diols, diethylene glycol (DEG), polyethylene glycol etc. that described antifreezing agent comprises;
Described stabilizing agent comprises the mixing of one or more in xylitol, mannitol, pentaerythrite, triphenyl phosphite, sodium citrate etc.;
Described thickener comprises the mixing of one or more in polyvinyl alcohol, polyvinyl acetate, xanthans, gelatin, gum Arabic, polyvinylpyrrolidone, aluminium-magnesium silicate, phenolic resins, CMC, sodium alginate etc.;
Described defoamer comprises silicone oil, silicone compound, C
10-20saturated fat acid compounds, C
8-10the mixing of one or more of fatty alcohol;
Described wetting agent comprises the mixing of one or more in lauryl sodium sulfate, neopelex, sodium butylnaphthalenesulfonate, petroleum sodium sulfonate, wetting and penetrating agent F, Nekal BX, the withered powder of tea, spaonin powder, soapberry powder;
Described dispersant comprises the mixing of one or more in lignosulfonates, polycarboxylate, alkylphenol polyoxyethylene sulphate, alkyl benzene sulfonate calcium salt, fatty acid ester sulphate, alkylphenol polyoxyethylene, sodium metnylene bis-naphthalene sulfonate, fatty alcohol-polyoxyethylene ether etc.;
Described filler comprises the mixing of one or more in precipitated calcium carbonate, potter's clay, kaolin, diatomite, bentonite, white carbon, clay, talcum powder, quartz sand etc.;
Described disintegrant comprises the mixing of one or more in sodium bicarbonate, magnesium chloride, aluminium chloride, sodium chloride, urea, ammonium sulfate, bentonite etc.
3. a purposes for Pesticidal combination, is characterized in that Pesticidal combination containing HNPC-A8008 and Avermectin is for preventing and treating vegetables, paddy rice, the Lepidoptera of fruit tree and flower crop and homoptera pest.
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CN113693062A (en) * | 2021-09-16 | 2021-11-26 | 江苏功成生物科技有限公司 | Injection for pine trees |
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CN1899042A (en) * | 2006-07-17 | 2007-01-24 | 王正权 | Pesticide composition of butene fipronil and low toxic pesticide |
CN1943353A (en) * | 2006-11-07 | 2007-04-11 | 深圳诺普信农化股份有限公司 | Pest killing composition with synergistic function containing fipronil and abamectin |
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CN113693062A (en) * | 2021-09-16 | 2021-11-26 | 江苏功成生物科技有限公司 | Injection for pine trees |
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