CN104507949B - 高纯度的含氮杂环化合物的制造方法 - Google Patents
高纯度的含氮杂环化合物的制造方法 Download PDFInfo
- Publication number
- CN104507949B CN104507949B CN201380040271.3A CN201380040271A CN104507949B CN 104507949 B CN104507949 B CN 104507949B CN 201380040271 A CN201380040271 A CN 201380040271A CN 104507949 B CN104507949 B CN 104507949B
- Authority
- CN
- China
- Prior art keywords
- compound
- mixture
- solvent
- mixed
- manufacture method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 0 C*1(C)C=C[C@](CC(*)C(C2)=C(*)C[C@@](C*C(*)=O)N)C2*1 Chemical compound C*1(C)C=C[C@](CC(*)C(C2)=C(*)C[C@@](C*C(*)=O)N)C2*1 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012-215046 | 2012-09-27 | ||
| JP2012215046 | 2012-09-27 | ||
| PCT/JP2013/076330 WO2014051077A1 (ja) | 2012-09-27 | 2013-09-27 | 高純度の含窒素複素環化合物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104507949A CN104507949A (zh) | 2015-04-08 |
| CN104507949B true CN104507949B (zh) | 2017-07-28 |
Family
ID=50388470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380040271.3A Expired - Fee Related CN104507949B (zh) | 2012-09-27 | 2013-09-27 | 高纯度的含氮杂环化合物的制造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9464095B2 (enExample) |
| JP (1) | JPWO2014051077A1 (enExample) |
| CN (1) | CN104507949B (enExample) |
| IN (1) | IN2015DN03012A (enExample) |
| WO (1) | WO2014051077A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104507948B (zh) * | 2012-09-27 | 2017-05-03 | 日产化学工业株式会社 | 含氮杂环n‑氧化物化合物的制造方法 |
| TWI844607B (zh) | 2018-12-28 | 2024-06-11 | 國立大學法人大阪大學 | 遺傳性徐脈性心律不整治療藥 |
| JP7733887B2 (ja) | 2020-06-26 | 2025-09-04 | 国立大学法人大阪大学 | 薬剤誘発性徐脈および徐脈性不整脈治療薬 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030045719A1 (en) * | 1996-11-01 | 2003-03-06 | Osi Pharmaceuticals, Inc. | Preparation of a camptothecin derivative by intramolecular cyclisation |
| WO2006048425A1 (en) * | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for making a non-nucleoside hiv-1 reverse transcriptase inhibitor |
| CN1898211A (zh) * | 2003-12-26 | 2007-01-17 | 日产化学工业株式会社 | 喹啉化合物的晶形及其生产方法 |
| CN101429200A (zh) * | 2004-03-23 | 2009-05-13 | 日产化学工业株式会社 | 用作抗心律失常剂的三环苯并吡喃化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5126540B2 (ja) | 2006-03-10 | 2013-01-23 | 日産化学工業株式会社 | 光学活性クロメンオキシド化合物の製造方法 |
| CN104507948B (zh) * | 2012-09-27 | 2017-05-03 | 日产化学工业株式会社 | 含氮杂环n‑氧化物化合物的制造方法 |
-
2013
- 2013-09-27 US US14/431,237 patent/US9464095B2/en not_active Expired - Fee Related
- 2013-09-27 WO PCT/JP2013/076330 patent/WO2014051077A1/ja not_active Ceased
- 2013-09-27 CN CN201380040271.3A patent/CN104507949B/zh not_active Expired - Fee Related
- 2013-09-27 JP JP2014538640A patent/JPWO2014051077A1/ja active Pending
- 2013-09-27 IN IN3012DEN2015 patent/IN2015DN03012A/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030045719A1 (en) * | 1996-11-01 | 2003-03-06 | Osi Pharmaceuticals, Inc. | Preparation of a camptothecin derivative by intramolecular cyclisation |
| CN1898211A (zh) * | 2003-12-26 | 2007-01-17 | 日产化学工业株式会社 | 喹啉化合物的晶形及其生产方法 |
| CN101429200A (zh) * | 2004-03-23 | 2009-05-13 | 日产化学工业株式会社 | 用作抗心律失常剂的三环苯并吡喃化合物 |
| WO2006048425A1 (en) * | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for making a non-nucleoside hiv-1 reverse transcriptase inhibitor |
Also Published As
| Publication number | Publication date |
|---|---|
| US9464095B2 (en) | 2016-10-11 |
| CN104507949A (zh) | 2015-04-08 |
| JPWO2014051077A1 (ja) | 2016-08-25 |
| IN2015DN03012A (enExample) | 2015-10-02 |
| US20150239899A1 (en) | 2015-08-27 |
| WO2014051077A1 (ja) | 2014-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170728 Termination date: 20190927 |