CN104483488A - 肾损伤和肾衰竭的诊断及预后的方法及组合物 - Google Patents

肾损伤和肾衰竭的诊断及预后的方法及组合物 Download PDF

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Publication number
CN104483488A
CN104483488A CN201410573713.7A CN201410573713A CN104483488A CN 104483488 A CN104483488 A CN 104483488A CN 201410573713 A CN201410573713 A CN 201410573713A CN 104483488 A CN104483488 A CN 104483488A
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urine
measured
plasma concentration
concentration
experimenter
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English (en)
Chinese (zh)
Inventor
J·安德贝里
J·格雷
P·麦克弗森
K·中村
J·P·坎普夫
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Astute Medical Inc
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Astute Medical Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4748Details p53
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775Apolipopeptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201410573713.7A 2009-08-28 2010-08-27 肾损伤和肾衰竭的诊断及预后的方法及组合物 Pending CN104483488A (zh)

Applications Claiming Priority (28)

Application Number Priority Date Filing Date Title
US23812709P 2009-08-28 2009-08-28
US23811809P 2009-08-28 2009-08-28
US23811509P 2009-08-28 2009-08-28
US23812809P 2009-08-28 2009-08-28
US23812309P 2009-08-28 2009-08-28
US23812509P 2009-08-28 2009-08-28
US23812109P 2009-08-28 2009-08-28
US23812009P 2009-08-28 2009-08-28
US23813409P 2009-08-28 2009-08-28
US23812909P 2009-08-28 2009-08-28
US61/238,120 2009-08-28
US61/238,115 2009-08-28
US61/238,121 2009-08-28
US61/238,129 2009-08-28
US61/238,128 2009-08-28
US61/238,123 2009-08-28
US61/238,118 2009-08-28
US61/238,125 2009-08-28
US61/238,127 2009-08-28
US61/238,134 2009-08-28
US24399709P 2009-09-18 2009-09-18
US24399109P 2009-09-18 2009-09-18
US24400209P 2009-09-18 2009-09-18
US24399309P 2009-09-18 2009-09-18
US61/243,997 2009-09-18
US61/244,002 2009-09-18
US61/243,993 2009-09-18
US61/243,991 2009-09-18

Related Parent Applications (1)

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CN201080045575.5A Division CN102792161B (zh) 2009-08-28 2010-08-27 肾损伤和肾衰竭的诊断及预后的方法及组合物

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CN104483488A true CN104483488A (zh) 2015-04-01

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CN201410573713.7A Pending CN104483488A (zh) 2009-08-28 2010-08-27 肾损伤和肾衰竭的诊断及预后的方法及组合物
CN201080045575.5A Expired - Fee Related CN102792161B (zh) 2009-08-28 2010-08-27 肾损伤和肾衰竭的诊断及预后的方法及组合物

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Country Status (9)

Country Link
US (2) US20120315649A1 (https=)
EP (3) EP2470905B1 (https=)
JP (2) JP5775874B2 (https=)
CN (2) CN104483488A (https=)
AU (1) AU2010286559B2 (https=)
CA (1) CA2772336A1 (https=)
HK (1) HK1208074A1 (https=)
NZ (2) NZ598712A (https=)
WO (1) WO2011025917A1 (https=)

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CN121186383A (zh) * 2025-11-24 2025-12-23 华中科技大学 慢性肾病的蛋白质标志物的筛选及应用

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NZ606124A (en) * 2010-06-23 2015-05-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
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US20150168422A1 (en) * 2011-05-12 2015-06-18 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US10935548B2 (en) 2011-12-08 2021-03-02 Astute Medical, Inc. Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2
EP3699591A1 (en) * 2012-04-02 2020-08-26 Astute Medical, Inc. Methods for diagnosis and prognosis of sepsis
EP3361255B1 (en) 2013-01-17 2020-03-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN104569417B (zh) * 2013-10-12 2016-06-01 广州瑞博奥生物科技有限公司 一种用于早期诊断急性肾损伤的抗体芯片试剂盒
CN110007084B (zh) 2013-12-03 2022-11-18 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
US11243202B2 (en) 2015-04-09 2022-02-08 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN107735147A (zh) * 2015-05-12 2018-02-23 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
EP3465201A4 (en) 2016-06-06 2020-08-26 Astute Medical, Inc. MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR
KR20210019459A (ko) * 2018-05-24 2021-02-22 레니버스 테라퓨틱스, 인크. 신장 손상 및 신부전 위험이 있는 환자를 치료하는 방법
CN117825674A (zh) * 2023-12-28 2024-04-05 南方医科大学南方医院 用于评估肝病预后的分子标志物及诊断试剂盒

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Also Published As

Publication number Publication date
JP2015212704A (ja) 2015-11-26
EP2470905A1 (en) 2012-07-04
JP5775874B2 (ja) 2015-09-09
CN102792161B (zh) 2014-11-12
JP6054481B2 (ja) 2016-12-27
EP3151005A1 (en) 2017-04-05
HK1208074A1 (en) 2016-02-19
US20150204892A1 (en) 2015-07-23
CN102792161A (zh) 2012-11-21
JP2013503344A (ja) 2013-01-31
HK1172691A1 (en) 2013-04-26
EP2470905B1 (en) 2015-01-07
EP2894473A1 (en) 2015-07-15
NZ598712A (en) 2014-05-30
CA2772336A1 (en) 2011-03-03
NZ624609A (en) 2015-12-24
EP2470905A4 (en) 2013-08-14
EP2894473B1 (en) 2016-09-21
AU2010286559A1 (en) 2012-04-05
US20120315649A1 (en) 2012-12-13
WO2011025917A1 (en) 2011-03-03
AU2010286559B2 (en) 2015-01-22

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