CN104435116A - Unguent for treating chilblain - Google Patents

Unguent for treating chilblain Download PDF

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Publication number
CN104435116A
CN104435116A CN201410748133.7A CN201410748133A CN104435116A CN 104435116 A CN104435116 A CN 104435116A CN 201410748133 A CN201410748133 A CN 201410748133A CN 104435116 A CN104435116 A CN 104435116A
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CN
China
Prior art keywords
parts
chilblain
vaseline
unguent
ointment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410748133.7A
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Chinese (zh)
Inventor
李汉州
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUIXIAN LIVELIHOOD PILLOW Co Ltd
Original Assignee
SUIXIAN LIVELIHOOD PILLOW Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by SUIXIAN LIVELIHOOD PILLOW Co Ltd filed Critical SUIXIAN LIVELIHOOD PILLOW Co Ltd
Priority to CN201410748133.7A priority Critical patent/CN104435116A/en
Publication of CN104435116A publication Critical patent/CN104435116A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Abstract

The invention discloses an unguent for treating chilblain. The unguent is prepared from the following medicinal raw materials in parts by weight: 900-1100 parts of Vaseline, 25-35 parts of camphor and 35-55 parts of cinnamon. A preparation method comprises the following steps: (1) weighing the medicinal raw materials in weight proportion and grinding cinnamon to fine powder for later use; (2) adding Vaseline into the fine powder, and after fully and uniformly stirring, adding camphor thereinto to prepare a pasty medicine; and (3) after fully stirring the pasty medicine, subpackaging to prepare the unguent. The unguent disclosed by the invention has the characteristics of sterilizing, relieving itching, diminishing swelling and being low in cost, quick to take effect, short in treatment course, remarkable in curative effect, free of irritation and toxic and side effects, simple in formula and high in cure rate.

Description

A kind of ointment for the treatment of chilblain
Technical field
The present invention relates to a kind of Chinese medicine ointment, particularly relate to a kind of ointment for the treatment of chilblain.
Background technology
Chilblain is common in winter, and due to local skin erythema, the tumidus infringement repeatedly that very cold causes, vesicle, ulcer can appear in severe patient, and the course of disease is slow, and weather turns warm rear spontaneous recovery, easily recurs.Cold is the main cause of chilblain morbidity.Its pathogenic factor be the skin of chilblain patient when running into cold (0 ~ 10 DEG C), the moist or changes in temperature sudden turn of events, local small artery shrinks, arteries paralysis of a specified duration and expanding, venous congestion, and local blood circulation is bad and fall ill.In addition, the factor such as humidity of skin, tip blood capillary deformity, autonomic nerve dysfunction, malnutrition, dyshormonia of patient self also may participate in morbidity.Lack the generation that the factors such as motion, acrohyperhidrosis humidity, footgear tension and long-term outdoor low operating temperatures all can cause chilblain.Chilblain is apt to occur in early winter, early spring, and with child, women and peripheral blood circulation, bad person is common, the performances such as these patients often send out cool with acral body skin, acrocyanosis, hyperhidrosis.Skin lesion is apt to occur in the places such as finger, the back of the hand, face, auricle, toes, sufficient edge, heel, the distribution of normal both sides.Common infringement is the edematous erythema of the congestive dark violet redness protuberance of limitation, and indefinite border, edge is cerise, and surface is nervous glossy, and matter is soft.Local pressing can be faded, and goes to press rear redness to recover gradually.Can there is vesicle in severe patient, break and form rotten to the corn or ulcer, retain pigmentation or atrophic scar more afterwards.Gargalesthesia is obvious, aggravates after heated, pain after festering.Chilblain is the commonly encountered diseases in winter, and according to relevant statistics, China has 200,000,000 people to be subject to the puzzlement of chilblain every year, wherein mainly child, women and old people.Chilblain, once occur, normal more difficult rapid healing in cold season, just can heal after day cyclostrophic be waited warm gradually.At present, the method for the treatment of chilblain is a lot, though the medicine of existing treatment chilblain has certain curative effect, onset is comparatively slow, and therapeutic effect is poor, and local excitation is larger.Mostly there is the deficiency that the course for the treatment of is long, curative effect is slow, especially for the chilblain of festering, curative effect is more undesirable.About the treatment of chilblain, China's Chinese medicine also has many prescriptions, but there is prescription complexity, high in cost of production problem more.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of ointment for the treatment of chilblain.It has sterilizing, antipruritic, detumescence, cost low, instant effect, short treating period, evident in efficacy, non-stimulated, have no side effect, the feature that prescription is simple, cure rate is high.
For solving the problem, the invention provides a kind of ointment for the treatment of chilblain.It is formulated by the crude drug of following weight portion: vaseline 900-1100 part, Camphora 25-35 part, Cortex Cinnamomi 35-55 part.
Preparation method of the present invention.Comprise the following steps:
(1) take above-mentioned each crude drug by weight ratio, Cortex Cinnamomi is ground into smalls is for subsequent use;
(2) vaseline is added in above-mentioned smalls, after stirring, then Camphora is added wherein, furnishing cream drug;
(3), after fully being stirred by above-mentioned cream drug, namely subpackage completes pharmacy.
Each crude drug component in the present invention: vaseline is a kind of sebaceous oil product.Dropping point is about 37-54 degree.Be by the Residual oil of oil through sulphuric acid and clay-filtered and obtain, also can be modulated by paraffin wax hydrocarbon and mineral lubricating oil and form.Vaseline system petroleum oil fraction, colourless, the oily liquids that odorless, unstressed configuration are transparent that obtain through deep refining, not containing any additive, moisture and mechanical admixture.Be dissolved in the organic solvents such as ether, chloroform, gasoline and benzene.Chemical stability and non-oxidizability well, have good anti-oxidative stability, stability and light stability.By the difference of its instructions for use, common vaseline, medicinal vaseline, cosmetic vaseline, industrial vaseline and capacitor vaseline etc. can be divided into.Camphora, another name camphor, splendid brain, brain, oily brain, tree brain are root, dry, branch, the leaf crystallization product through refining of Lauraceae magaphanerophytes Camphor tree.Pungent, hot.GUIXIN, liver, spleen channel.1. killing parasites for relieving itching: itch for scabies skin ulcer, has dehumidifying parasite killing, antipruritic effect.2. reducing swelling and alleviating pain: for tumbling down damage, the stagnant multiple pain card such as to swell and ache of the stasis of blood.3. ward off and dirtyly to have one's ideas straightened out: for fainting suddenly or coma etc.[pharmacological action] 1. has local excitation and antisepsis.2. pair nervus centralis has excitation.3. there is cardiotonic.4. pair common causative fungus has inhibitory action.Can local blood circulation be improved, can mucosal secretions be promoted.Cortex Cinnamomi calls male osmanthus, purple osmanthus, great Gui, peppery osmanthus, Cortex cinnamomi japonici (Ramulus Cinnamomi), beautiful osmanthus, Cortex Cinnamomi, osmanthus, cylinder osmanthus, is dried bark and the branch skin in canella Cortex Cinnamomi and osmanthus, great Ye Qinghua.Effect of Cortex Cinnamomi and effect :cortex Cinnamomi extremely hot in nature, acrid in the mouth, sweet.Cure mainly: insufficiency of kidney-YANG; Gate of vitality's fire aversion to cold and cold limbs; Soreness of the waist and knees; Impotence and seminal emission; Dysuria or frequency; To lose heart dyspnea with rapid and short breath; The all cards of edema oliguria; Decline of the fire from the gate of life; Fire is Gui Yuan not; Floating YANG; Refusing yang; And heat in the upper and cold in the lower; Flushed complexion cold foot; Dizziness and tinnitus; Dispute gruel is broken; Spleen-kidney vacuity cold; Coldness and pain in the epigastrium; Decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile; Dysmenorrhea amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Carbuncle of yin nature multiple abscess; Or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus; Or do not hold back after bursting.
Compared with prior art, the beneficial effect that the present invention obtains is: by by above-mentioned each crude drug reasonable compatibility by weight ratio, the ointment prepared by above-mentioned manufacture method.It has sterilizing, antipruritic, detumescence, cost low, instant effect, short treating period, evident in efficacy, non-stimulated, have no side effect, the feature that prescription is simple, cure rate is high.
Detailed description of the invention
Embodiment 1: a kind of ointment for the treatment of chilblain, it is formulated by the crude drug of following weight portion: 900 parts, vaseline, Camphora 25 parts, Cortex Cinnamomi 35 parts.
Preparation method of the present invention.Comprise the following steps:
(1) take above-mentioned each crude drug by weight ratio, Cortex Cinnamomi is ground into smalls is for subsequent use;
(2) vaseline is added in above-mentioned smalls, after stirring, then Camphora is added wherein, furnishing cream drug;
(3), after fully being stirred by above-mentioned cream drug, namely subpackage completes pharmacy.
Usage of the present invention and consumption: affected part warm water cleans up, and ointment is coated in affected part, and with gauze wrapping, every day 2-3 time, within general chilblain 2-3 days, can cure.
Embodiment 2: a kind of ointment for the treatment of chilblain, it is formulated by the crude drug of following weight portion: 1000 parts, vaseline, Camphora 30 parts, Cortex Cinnamomi 45 parts.
Preparation method of the present invention.Comprise the following steps:
(1) take above-mentioned each crude drug by weight ratio, Cortex Cinnamomi is ground into smalls is for subsequent use;
(2) vaseline is added in above-mentioned smalls, after stirring, then Camphora is added wherein, furnishing cream drug;
(3), after fully being stirred by above-mentioned cream drug, namely subpackage completes pharmacy.
Usage of the present invention and consumption: affected part warm water cleans up, and ointment is coated in affected part, and with gauze wrapping, every day 2-3 time, within general chilblain 2-3 days, can cure.
Embodiment 3: a kind of ointment for the treatment of chilblain, it is formulated by the crude drug of following weight portion: 1100 parts, vaseline, Camphora 35 parts, Cortex Cinnamomi 55 parts.
Preparation method of the present invention.Comprise the following steps:
(1) take above-mentioned each crude drug by weight ratio, Cortex Cinnamomi is ground into smalls is for subsequent use;
(2) vaseline is added in above-mentioned smalls, after stirring, then Camphora is added wherein, furnishing cream drug;
(3), after fully being stirred by above-mentioned cream drug, namely subpackage completes pharmacy.
Usage of the present invention and consumption: affected part warm water cleans up, and ointment is coated in affected part, and with gauze wrapping, every day 2-3 time, within general chilblain 2-3 days, can cure.
In conjunction with detailed description of the invention, the present invention is explained in detail above, but the present invention is not limited to above-mentioned embodiment, in the ken that those of ordinary skill in the art possess, many variations can also be made to it.
The result of clinical observation of the present invention is as follows:
Model case:
Case one Liu, man, 23 years old, Suixian County, Henan Province outskirts of a town village people, when in January, 2007 goes to a doctor, occur blister ulceration after right hand cold injury, the several months did not heal, and through using ointment of the present invention, within 3 days, is almost recovered.
Case two so-and-so, man, 48 years old, when in April, 2008 goes to a doctor, there is blister ulceration after the cold injury of foot many places, very itch unbearably in Henan Province Shangqiu people from county, through using ointment of the present invention, within 3 days, is almost recovered.
Case three Zheng, female, 18 years old, winter in 2010, ear's chilblain, very itched unbearably, smeared the recovery from illness in 2 days of this cream.
Case four Guo so-and-so, female, 10 years old, people from Ningling County, Henan Province, when in December, 2012 is gone to a doctor, both hands and ear face cold injury, through using ointment of the present invention, 2 days skin recovered normal.

Claims (5)

1. treat an ointment for chilblain, it is formulated by the crude drug of following weight portion: vaseline 900-1100 part, Camphora 25-35 part, Cortex Cinnamomi 35-55 part.
2. the ointment for the treatment of chilblain as claimed in claim 1, it is formulated by the crude drug of following weight portion: 900 parts, vaseline, Camphora 25 parts, Cortex Cinnamomi 35 parts.
3. the ointment for the treatment of chilblain as claimed in claim 1, it is formulated by the crude drug of following weight portion: 1000 parts, vaseline, Camphora 30 parts, Cortex Cinnamomi 45 parts.
4. the ointment for the treatment of chilblain as claimed in claim 1, it is formulated by the crude drug of following weight portion: 1100 parts, vaseline, Camphora 35 parts, Cortex Cinnamomi 55 parts.
5. the preparation method of the ointment of the treatment chilblain according to any one of Claims 1-4, is characterized in that: described preparation method comprises the following steps:
(1) take above-mentioned each crude drug by weight ratio, Cortex Cinnamomi is ground into smalls is for subsequent use;
(2) vaseline is added in above-mentioned smalls, after stirring, then Camphora is added wherein, furnishing cream drug;
(3), after fully being stirred by above-mentioned cream drug, namely subpackage completes pharmacy.
CN201410748133.7A 2014-12-10 2014-12-10 Unguent for treating chilblain Pending CN104435116A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410748133.7A CN104435116A (en) 2014-12-10 2014-12-10 Unguent for treating chilblain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410748133.7A CN104435116A (en) 2014-12-10 2014-12-10 Unguent for treating chilblain

Publications (1)

Publication Number Publication Date
CN104435116A true CN104435116A (en) 2015-03-25

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497134A (en) * 2016-01-19 2016-04-20 广西复鑫益生物科技有限公司 Pharmaceutical composition for treating pruritus heimalis and preparation method of pharmaceutical composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1151308A (en) * 1995-12-01 1997-06-11 倪德平 Medicine for curing chilblain
CN1433793A (en) * 2002-01-22 2003-08-06 胡宝山 Ointment for treating chilblain
CN101485725A (en) * 2008-01-16 2009-07-22 北京天科仁祥医药科技有限公司 Gel for treating chilblain and preparation method thereof
CN101485727A (en) * 2009-02-07 2009-07-22 陈恒树 External-use tinctura for treating chilblain

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1151308A (en) * 1995-12-01 1997-06-11 倪德平 Medicine for curing chilblain
CN1433793A (en) * 2002-01-22 2003-08-06 胡宝山 Ointment for treating chilblain
CN101485725A (en) * 2008-01-16 2009-07-22 北京天科仁祥医药科技有限公司 Gel for treating chilblain and preparation method thereof
CN101485727A (en) * 2009-02-07 2009-07-22 陈恒树 External-use tinctura for treating chilblain

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
徐育等: ""冻疮研究进展"", 《辽宁中医药大学学报》 *
李彦龙: "《24节气顺时调养·秋冬卷》", 31 August 2014 *
王世军等: ""中医药治疗冻疮进展"", 《河南中医》 *
贺菊乔等: "《实用外科手册》", 30 September 2008 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105497134A (en) * 2016-01-19 2016-04-20 广西复鑫益生物科技有限公司 Pharmaceutical composition for treating pruritus heimalis and preparation method of pharmaceutical composition

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Application publication date: 20150325

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