CN106728168B

CN106728168B - A Chinese medicinal external preparation for treating eczema and psoriasis, and its preparation method

Info

Publication number: CN106728168B
Application number: CN201710042768.9A
Authority: CN
Inventors: 张颖
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-01-20
Filing date: 2017-01-20
Publication date: 2020-02-04
Anticipated expiration: 2037-01-20
Also published as: CN106728168A

Abstract

The invention discloses a traditional Chinese medicine external preparation for treating eczema and psoriasis and a preparation method thereof, the traditional Chinese medicine external preparation comprises 25-50 parts of radix sophorae flavescentis, 25-50 parts of fructus kochiae, 20-40 parts of cortex dictamni, 20-40 parts of raw rhubarb, 20-40 parts of purslane, 10-30 parts of divaricate saposhnikovia root, 10-30 parts of herba schizonepetae, 5-20 parts of alum, 8-15 parts of fructus cnidii, 20-40 parts of sanguisorba officinalis, 5-20 parts of cape jasmine and 20-40 parts of herba siegesbeckiae, the crushed raw rhubarb powder is firstly placed in cold water for infiltration, then the alum and hot water are added, and after the alum is dissolved in hot water, infiltration is carried out, and then leachate; then decocting the rest sliced mixture twice, standing and filtering the twice decocted filtrate to obtain a concentrated solution; finally, the prepared percolate and the concentrated solution are mixed evenly, and then sodium benzoate is added, so that the traditional Chinese medicine external preparation for treating eczema and psoriasis can be prepared. The preparation has high cure rate, low recurrence rate, small irritation, and no toxic and side effects after long-term use.

Description

A Chinese medicinal external preparation for treating eczema and psoriasis, and its preparation method

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine external preparation for treating eczema and psoriasis and a preparation method thereof.

Background

Eczema is a common skin disease, has complex etiology and severe clinical manifestation pruritus, is mainly characterized by herpes simplex in the acute stage and has a exudation tendency, and is easily and repeatedly attacked in the chronic stage, mainly characterized by lichenification. The eczematoid dermatitis is also a common disease and frequently encountered disease of dermatology, is an allergic skin disease caused by complex internal and external exciting factors, is governed by genetic factors and is influenced by health conditions and environmental factors, on the basis of infection focuses, erosion occurs to surrounding skin, the course of disease of a patient is long, itching is severe, the recurrence is strong, the rash surface of the patient is often accompanied by superficial fungal or bacterial infection or cross infection of the superficial fungal or bacterial infection and the like, great pain is brought to the patient, and the physical and mental health and the normal life of the patient are also seriously influenced.

Psoriasis, also known as psoriasis vulgaris, is also a common chronic skin disease, and is characterized in that papules and erythema with different sizes appear, the surface is covered with silvery-white scales, the boundary is clear, the psoriasis is better developed on the scalp, the extending sides and the back of four limbs, and the excessive female of common men is easy to relapse or aggravate in spring and winter, but is relieved in summer and autumn, the cause of the psoriasis is not clear, and the psoriasis can be radically cured by removing a medicine, and is one of ten stubborn diseases positioned by the world health organization because the psoriasis is difficult to radically cure, easy to relapse and delayed to cure.

At present, the traditional Chinese and western medicine treatment of eczema, psoriasis and the like has no breakthrough progress, the treatment methods are more, but most of the traditional Chinese and western medicine treatment methods can only achieve the near-term clinical curative effect or temporarily relieve symptoms, and no good radical treatment method exists at present. In the existing western medicine treatment technology, a treatment mode of combining oral medicines and external medicines is generally adopted for treating eczema and psoriasis so as to achieve the purpose of relieving or inhibiting the state of an illness. At present, the main oral drugs include anti-tumor and immunosuppressive drugs, immunomodulators, glucocorticoid drugs, cytostatics, reducing agents, antibiotics, keratolytic agents and the like, the external drugs include coal tar, salicylic acid, anthralin, corticosteroid hormones, vitamin D3 derivatives and the like, and the external drugs have obvious effect of eliminating skin lesions in a short time.

With the development of traditional Chinese medicine, traditional Chinese medicine plays an important role in modern treatment of eczema and psoriasis, has relatively rich treatment experience, is accepted by more and more people, gains the praise of many patients, and has more external traditional Chinese medicine preparations for treating eczema and psoriasis, such as common ointment, Jinghong powder ointment, Douqing ointment, Yuhuang ointment, hong powder ointment, camptothecin ointment, Binghuangfule ointment and the like; the Binghuangfule ointment is an emulsion-type lime ointment and has the effects of clearing heat, eliminating dampness, promoting blood circulation, dispelling wind, relieving itching and diminishing inflammation, but in the clinical application process, strong irritation is still found, and the ointment cannot achieve good eradication effect on eczema and psoriasis, so that on the whole, no ideal and exact traditional Chinese medicine treatment medicine which does not need to be taken orally is provided for eczema and psoriasis at present. Therefore, the development of a traditional Chinese medicine external preparation for treating eczema and psoriasis, which has the advantages of good curative effect, no irritation when being used in a large area, small toxic and side effects, convenient use, capability of improving the compliance of patients and reducing the administration times, and a preparation method thereof are objectively needed.

Disclosure of Invention

In order to solve the problems in the background art, the invention aims to provide a traditional Chinese medicine external preparation for treating eczema and psoriasis, which has the advantages of good curative effect, no irritation when being used in a large area, small toxic and side effects, convenient use, capability of improving the compliance of patients and reducing the administration frequency, and a preparation method thereof.

A traditional Chinese medicine external preparation for treating eczema and psoriasis comprises the following raw materials in parts by weight: 25-50 parts of radix sophorae flavescentis, 25-50 parts of fructus kochiae, 20-40 parts of cortex dictamni, 20-40 parts of raw rhubarb, 20-40 parts of purslane, 10-30 parts of divaricate saposhnikovia root, 10-30 parts of herba schizonepetae, 5-20 parts of alum, 8-15 parts of fructus cnidii, 20-40 parts of garden burnet root, 5-20 parts of cape jasmine fruit and 20-40 parts of herba siegesbeckiae.

The preparation method comprises the following steps:

① preparing materials, weighing the above raw materials, removing impurities, pulverizing radix Et rhizoma Rhei into radix Et rhizoma Rhei powder, slicing the rest materials, and mixing;

②, percolating, namely putting the raw rhubarb powder crushed in the step ① into cold water for infiltrating, wherein the amount of the cold water is 2-2.5 times of the mass of the raw rhubarb powder, infiltrating for 7-8 hours, adding alum into the infiltrated raw rhubarb powder, adding hot water at the temperature of 70-80 ℃, wherein the amount of the hot water is 9-10 times of the total mass of the raw rhubarb powder and the alum, stirring until the alum is completely dissolved in the hot water, naturally cooling the mixture, and percolating after the mixture is naturally cooled to obtain percolate;

③ decocting, namely soaking the radix sophorae flavescentis, the fructus kochiae, the cortex dictamni, the purslane, the radix sileris, the herba schizonepetae, the fructus cnidii, the garden burnet, the cape jasmine and the herba siegesbeckiae which are sliced and mixed in the step ① in cold water, wherein the amount of the cold water is 2-3 times of the total mass of the mixture, the cold water is used for soaking for 1-2 hours, then decocting is carried out by using low fire, the primary filtration is carried out after 1.5-2 hours of decoction, the primary filtrate is collected for standby, then the filter residue obtained by the primary filtration is added with the cold water 4-5 times of the mass of the filter residue for decoction, the secondary filtration is carried out after 1-1.5 hours of decoction, finally the secondary filtrate is obtained, the primary filtrate and the secondary filtrate are mixed uniformly, the mixture is kept stand for 8-10;

④, mixing the percolate obtained in step ② with the concentrated solution obtained in step ③ in a volume ratio of 3:7 to obtain a cape jasmine elm lotion, adding sodium benzoate into the cape jasmine elm lotion, wherein the volume of the sodium benzoate accounts for 0.3-0.6% of the total volume of the cape jasmine elm lotion, and stirring uniformly to obtain the traditional Chinese medicine external preparation for treating eczema and psoriasis.

The invention is prepared by adopting more than ten kinds of rare Chinese medicines on the basis of arranging a large amount of domestic and foreign literature data, the medicines cooperate with each other to play the roles of resisting inflammation, clearing away heat and toxic material, promoting diuresis, dispelling wind and arresting itching, and particularly after the medicated bath is assisted, the effects of penetrating and moistening dryness, promoting qi and blood circulation, warming and dredging channels and collaterals, moistening skin, dispelling wind and the like can be achieved, so that the activities of various tissues and organs are improved, the restoration and disease resistance of the organism are enhanced, and the aim of curing diseases is finally achieved. Meanwhile, the preparation is administrated through skin, so that the stimulation of gastrointestinal tracts caused by oral administration can be avoided, the blood concentration of the whole body is reduced, the medicine concentration of local affected parts is improved, the preparation has the advantages of reducing administration times, reducing toxic and side effects and being convenient to use, the compliance of patients can be greatly improved, and the preparation cannot be dependent on the patients. The preparation is a traditional Chinese medicine preparation, is not added with any chemical component, has no hormone, has remarkable treatment effect, does not generate irritation, has no toxic or side effect after long-term use, does not generate drug resistance and dependence, can thoroughly inhibit the development of skin diseases such as eczema, psoriasis and the like, reduces the recurrence frequency, improves the psychological or social life quality of patients, and has better popularization and utilization values.

Detailed Description

The present invention is further illustrated by the following examples, which are not intended to be limiting in any way, and any modifications or alterations based on the teachings of the present invention are intended to fall within the scope of the present invention.

Example 1:

the external traditional Chinese medicine preparation for treating eczema and psoriasis and the preparation method thereof in the embodiment 1 comprise the following steps:

① preparing materials, namely weighing 25 parts of radix sophorae flavescentis, 25 parts of fructus kochiae, 20 parts of cortex dictamni, 20 parts of raw rhubarb, 20 parts of purslane, 10 parts of radix sileris, 1 part of herba schizonepetae, 5 parts of alum, 8 parts of fructus cnidii, 20 parts of sanguisorba officinalis, 5 parts of fructus gardeniae and 20 parts of herba siegesbeckiae, removing impurities, crushing the raw rhubarb into raw rhubarb powder for later use, slicing and mixing the rest radix sophorae flavescentis, fructus kochiae, cortex dictamni, purslane, radix sileris, schizonepeta, fructus cnidii, garden burnet, fructus gardeniae and herba siegesbeckiae for later use, wherein the powder granularity of the raw rhubarb powder is all smaller than 24 meshes, wherein the powder with the granularity smaller than or equal to 50 meshes is not larger than 40 percent, the purslane and the herba schizonepetae are dried stems and leaves, the cortex dictamni is dried root bark, the fructus kochiae and the fructus cnidii are dried mature fruits, the radix sanguisorbae, the dried roots and the dried;

②, percolating, namely putting the raw rhubarb powder crushed in the step ① into cold water for infiltrating, wherein the amount of the cold water is 2 times of the mass of the raw rhubarb powder, infiltrating for 7 hours, adding alum into the infiltrated raw rhubarb powder, adding hot water at the temperature of 80 ℃, wherein the amount of the hot water is 9 times of the total mass of the raw rhubarb powder and the alum, stirring until the alum is completely dissolved in the hot water, naturally cooling the mixture, and percolating at the flow rate of 2400-2500 mL/h after the mixture is naturally cooled to obtain percolate;

③ decocting, namely soaking the radix Sophorae Flavescentis, fructus Kochiae, cortex Dictamni, herba Portulacae, radix Saposhnikoviae, herba Schizonepetae, fructus Cnidii, radix Sanguisorbae, fructus Gardeniae and herba Siegesbeckiae which are sliced and mixed in the step ① in cold water, wherein the amount of the cold water is 2 times of the total mass of the mixture, soaking for 1 hour, decocting with slow fire, decocting for 1.5 hours, filtering for one time, collecting the primary filtrate for later use, adding the filter residue obtained by the one-time filtration into cold water 4 times of the mass of the filter residue, decocting for 1 hour, filtering for the second time to obtain the secondary filtrate, mixing the primary filtrate and the secondary filtrate uniformly, standing for 8-10 hours, filtering again to remove precipitates, and obtaining the filtrate which is a concentrated solution after decoction and concentration;

④ mixing the percolate obtained in step ② with the concentrated solution obtained in step ③ at a volume ratio of 3:7 to obtain a cape jasmine fruit and elm lotion, adding sodium benzoate into the cape jasmine fruit and elm lotion, wherein the volume of the sodium benzoate is 0.3% of the total volume of the cape jasmine fruit and elm lotion, and stirring uniformly to obtain the traditional Chinese medicine external preparation for treating eczema and psoriasis.

Example 2

The external traditional Chinese medicine preparation for treating eczema and psoriasis and the preparation method thereof in the embodiment 2 comprise the following steps:

① preparing materials, namely weighing 30 parts of radix sophorae flavescentis, 30 parts of fructus kochiae, 30 parts of cortex dictamni, 30 parts of raw rhubarb, 30 parts of purslane, 20 parts of radix sileris, 20 parts of herba schizonepetae, 10 parts of alum, 10 parts of fructus cnidii, 30 parts of sanguisorba officinalis, 10 parts of fructus gardeniae and 30 parts of herba siegesbeckiae, removing impurities, pulverizing the raw rhubarb into raw rhubarb powder for later use, slicing and mixing the rest radix sophorae flavescentis, fructus kochiae, cortex dictamni, purslane, radix sileris, schizonepeta, fructus cnidii, garden burnet, fructus gardeniae and herba siegesbeckiae for later use, wherein the purslane and the schizonepeta are dried stems and leaves, the cortex dictamni is dried root bark, the fructus kochiae and the fructus cnidii are dried mature fruits, the radix sanguisorbae, the radix sileris and the herba siegesbeckiae are dried roots, the raw rhubarb is dried roots and;

② percolating, namely soaking the raw rhubarb powder crushed in the step ① in cold water, wherein the amount of the cold water is 2.5 times of the mass of the raw rhubarb powder, soaking for 8 hours, adding alum into the soaked raw rhubarb powder, adding hot water at the temperature of 80 ℃, wherein the amount of the hot water is 10 times of the total mass of the raw rhubarb powder and the alum, stirring until the alum is completely dissolved in the hot water, naturally cooling the mixture, and percolating at the flow rate of 2400-2500 mL/h after the mixture is naturally cooled to obtain percolate;

③ decocting, namely soaking the radix Sophorae Flavescentis, fructus Kochiae, cortex Dictamni, herba Portulacae, radix Saposhnikoviae, herba Schizonepetae, fructus Cnidii, radix Sanguisorbae, fructus Gardeniae and herba Siegesbeckiae which are sliced and mixed in the step ① in cold water, wherein the amount of the cold water is 3 times of the total mass of the mixture, decocting for 2 hours, decocting with slow fire, filtering for 2 hours, collecting primary filtrate for later use, adding the filter residue obtained by primary filtration into cold water 5 times of the mass of the filter residue, decocting for 1.5 hours, filtering for the second time to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate, standing for 8-10 hours, filtering again to remove precipitates, and obtaining filtrate which is concentrated solution after decoction;

④ mixing the percolate obtained in step ② with the concentrated solution obtained in step ③ at a volume ratio of 3:7 to obtain a cape jasmine fruit and elm lotion, adding sodium benzoate into the cape jasmine fruit and elm lotion, wherein the volume of the sodium benzoate is 0.5% of the total volume of the cape jasmine fruit and elm lotion, and stirring uniformly to obtain the traditional Chinese medicine external preparation for treating eczema and psoriasis.

Example 3:

the external traditional Chinese medicine preparation for treating eczema and psoriasis and the preparation method thereof in the embodiment 3 comprise the following steps:

① preparing materials, namely weighing 50 parts of radix sophorae flavescentis, 50 parts of fructus kochiae, 40 parts of cortex dictamni, 40 parts of raw rhubarb, 20 parts of purslane, 30 parts of radix sileris, 10 parts of herba schizonepetae, 20 parts of alum, 15 parts of fructus cnidii, 40 parts of sanguisorba officinalis, 20 parts of fructus gardeniae and 40 parts of herba siegesbeckiae, removing impurities, pulverizing the raw rhubarb into raw rhubarb powder for later use, slicing the rest radix sophorae flavescentis, fructus kochiae, cortex dictamni, purslane, radix sileris, schizonepeta, fructus cnidii, garden burnet, fructus gardeniae and herba siegesbeckiae, mixing the raw rhubarb powder with the granularity of less than 24 meshes, wherein the powder with the granularity of less than or equal to 50 meshes is not more than 40 percent, the purslane and the herba schizonepetae are dried stems and leaves, the cortex dictamni is dried root bark, the fructus kochiae and the fructus cnidii are dried mature fruits, the radix sanguisorbae, the radix sileris and the radix sophorae flavescentis are dried;

③ decocting radix Sophorae Flavescentis, fructus Kochiae, cortex Dictamni Radicis, herba Portulacae, radix Saposhnikoviae, herba Schizonepetae, fructus Cnidii, radix Sanguisorbae, fructus Gardeniae and herba Siegesbeckiae, which are sliced and mixed in step ①, in cold water, wherein the amount of cold water is 2.5 times of the total mass of the mixture, the mixture is decocted for 2 hours by slow fire, the decoction is carried out for 2 hours, primary filtration is carried out, primary filtrate is collected for standby application, the filter residue obtained by primary filtration is added with cold water 4.5 times of the mass of the filter residue for decoction, the decoction is carried out for 1.5 hours, secondary filtration is carried out to obtain secondary filtrate, the primary filtrate and the secondary filtrate are mixed uniformly, the mixture is kept stand for 8-10 hours, and the filtrate obtained after the precipitate is removed by secondary filtration is concentrated solution obtained after the decoction;

④ mixing the percolate obtained in step ② with the concentrated solution obtained in step ③ at a volume ratio of 3:7 to obtain a cape jasmine fruit and elm lotion, adding sodium benzoate into the cape jasmine fruit and elm lotion, wherein the volume of the sodium benzoate is 0.6% of the total volume of the cape jasmine fruit and elm lotion, and stirring uniformly to obtain the traditional Chinese medicine external preparation for treating eczema and psoriasis.

Example 4

The external traditional Chinese medicine preparation for treating eczema and psoriasis and the preparation method thereof in the embodiment 4 comprise the following steps:

① preparing materials, namely weighing 50 parts of radix sophorae flavescentis, 50 parts of fructus kochiae, 20 parts of cortex dictamni, 20 parts of raw rhubarb, 40 parts of purslane, 10 parts of radix sileris, 20 parts of herba schizonepetae, 5 parts of alum, 8 parts of fructus cnidii, 20 parts of sanguisorba officinalis, 20 parts of fructus gardeniae and 20 parts of herba siegesbeckiae, removing impurities, pulverizing the raw rhubarb into raw rhubarb powder for later use, slicing and mixing the rest radix sophorae flavescentis, fructus kochiae, cortex dictamni, purslane, radix sileris, schizonepeta, fructus cnidii, garden burnet, fructus gardeniae and herba siegesbeckiae for later use, wherein the purslane and the schizonepeta are dried stems and leaves, the cortex dictamni is dried root bark, the fructus kochiae and the fructus cnidii are dried mature fruits, the radix sanguisorbae, the radix sileris and the herba siegesbeckiae are dried roots, the raw rhubarb is dried roots and;

② percolating, namely soaking the raw rhubarb powder crushed in the step ① in cold water, wherein the amount of the cold water is 2.2 times of the mass of the raw rhubarb powder, adding alum into the soaked raw rhubarb powder after soaking for 8 hours, adding hot water at the temperature of 70 ℃, wherein the amount of the hot water is 9.5 times of the total mass of the raw rhubarb powder and the alum, stirring until the alum is completely dissolved in the hot water, naturally cooling the mixture, and percolating after natural cooling to obtain percolate;

④ mixing the percolate obtained in step ② with the concentrated solution obtained in step ③ at a volume ratio of 3:7 to obtain a cape jasmine fruit and elm lotion, adding sodium benzoate into the cape jasmine fruit and elm lotion, wherein the volume of the sodium benzoate is 0.45% of the total volume of the cape jasmine fruit and elm lotion, and stirring uniformly to obtain the traditional Chinese medicine external preparation for treating eczema and psoriasis.

In order to test the effect of the external preparation prepared in the embodiments 1 to 4 of the present invention on the treatment of eczema and psoriasis, the inventor selects 25 patients with eczema and psoriasis from people of different ages and different sexes, and performs treatment by using the reuse preparation prepared in the embodiments 1 to 4, and after one treatment course, the statistical findings are that: 25 cases of disease recovery account for 100%, and 1 recurrent case accounts for 4%. According to the statistics, the preparation disclosed by the invention is an external preparation, has the advantages of obvious treatment effect, no irritation, no dependence and small toxic and side effects, and is a traditional Chinese medicine external preparation which is good in treatment effect, safe, efficient and convenient to use.

Some typical cases are as follows:

typical case one:

patient is at first visit of 25 months and 7 months in 2016, and is a Yan Zhi, a male patient is at age 44 years old. The patients have the existing eczema history for 5 years, and before 10 days, no obvious inducement is found to cause the skin of the back, the upper arms and the thighs to be flushed, the skin is scattered on red papules and blisters, and part of blisters are fused into pieces, the surfaces of the blisters are broken and eroded, and the pruritus is obvious. A red tongue with a yellow and greasy coating and a slippery and rapid pulse. And (3) diagnosis: eczema (damp-heat accumulating in the skin). The preparation of the invention in the embodiment 1 is used for external washing and cold wet compress, 1 day is used for 3 times, and 5 days is 1 course of treatment. Taking 500mL of the preparation each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 35-40 ℃, dipping the liquid medicine by a towel, and washing the affected part for more than ten times repeatedly, wherein each time of washing is 15-20 minutes; after washing, taking 20mL of the preparation, putting 5-8 layers of sterile gauze into liquid medicine at the temperature of 4-15 ℃ for completely soaking, extruding out redundant liquid medicine, applying the liquid medicine to an affected part, frequently spraying the liquid medicine on compress for moisturizing, and each time for 15-20 minutes. After 5 days, the skin is slightly flushed, the broken erosion part is healed without exudation, part of skin lesion is dry and slight desquamation, the preparation is used for consolidating and treating 2 courses of treatment, after 10 days, the skin lesion is healed without subjective symptoms, and the disease is cured.

Typical case two:

the patient was initially diagnosed in 2016, 8 months and 2 days for a month after Sunzhi and a woman. The patients have the history of diabetes, eruption of double lower limbs is repeated for 8 years, the patients feel pruritus, the patients are diagnosed as eczema in a plurality of hospitals, and the patients are treated by oral administration and external application of a plurality of Chinese and Western medicaments, so that the skin lesions are lingering and difficult to heal, and the patients are mild, heavy and heavy. The coming diagnosis is as follows: the red papules on the front edges of the legs of the two lower limbs and the flush of the base are partially fused into pieces, and the skin damage surfaces have a little scale, no erosion, no exudation, obvious pruritus and insomnia. Pale with white coating and deep and slow pulse. And (3) diagnosis: eczema (spleen deficiency and dampness accumulation). The formulation of example 4 was applied by external washing, cold compress and wet compress for 3 times in 1 day, and 1 course of treatment was 5 days. Taking 500mL of the preparation each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 40-45 ℃, soaking the two lower limbs in the liquid medicine, dipping the liquid medicine in a towel, and washing the liquid medicine for more than ten times repeatedly, wherein the washing time is 15-20 minutes each time; after washing, taking 20mL of the preparation, putting 5-8 layers of sterile gauze into liquid medicine at the temperature of 4-15 ℃ for completely soaking, extruding out redundant liquid medicine, applying the liquid medicine to an affected part, frequently spraying the liquid medicine on compress for moisturizing, and each time for 15-20 minutes. After 2 days of treatment, the subjective pruritus is relieved for the most part, after 5 days of re-diagnosis, the skin lesion is removed, the basal flush is relieved, the discomfort such as pruritus and the like is avoided, 2 treatment courses of the gardenia elm lotion are continued, the rash of the two lower limbs disappears, the skin is smooth, a little pigmentation is left, no special discomfort exists, and the disease is cured.

Typical case three:

the patient is initially diagnosed in 8 months, 2016, 5 months and 13 days. After the complementary food is added, the skin rash begins to appear on the face of the infant, the color is red, a little exudation exists, the infant can scratch by itself and can be relieved by applying the infant eczema skin-care cream to the outside, but the treatment is repeated after 2 to 3 days after the administration is stopped. The coming diagnosis is as follows: facial millet-sized papules, blisters and flush basement, with parts fused into patches, skin lesions with a little exudation and small erosive surfaces after scratching, unclear edges, red tongue with white and greasy coating, purple fingerprints and hidden in the wind. And (3) diagnosis: eczema (damp-heat accumulating in the skin). The preparation of the embodiment 3 is applied to the affected part in a warm and humid manner for 3 times in 1 day, and 1 course of treatment lasts for 3 days. 20mL of the preparation is taken each time, 1 time of warm water is added for dilution, the water temperature is controlled to be 35-40 ℃, 5-8 layers of sterile gauze are placed in the liquid medicine for completely soaking, the liquid medicine is squeezed out and then applied to an affected part, and the liquid medicine is frequently sprayed on a compress for moisturizing for 10-15 minutes each time. After 3 days, the skin lesion is removed, the flush of the skin is relieved, the erosion part is healed, the exudation is obviously reduced, and mild desquamation exists, and then the gardenia elm lotion is used for 2 treatment courses to consolidate the treatment, so that the face rash disappears, and the skin is smooth.

Typical case four:

the patient is in full age, male, 33 years old, and the initial diagnosis is 20 days 9 months 2016. The patients do not have obvious inducement before 4 years, red papules, maculopapules and scales begin to appear on the trunk and the limbs, the red papules, the maculopapules and the scales gradually expand into red plaques with clear boundaries, silvery white scales are attached on the red papules, and the patients feel pruritus, and the red plaques are treated by most hospitals (detailed) and are good and bad in time and recurrent, the symptoms are aggravated again before 1 month, the pruritus is obvious, and the diseases are seen when coming to the clinic: the powder is scattered on red plaques throughout the body, covered with thick layers of silvery-white scales, difficult to bear itching, dry and desquamation of the skin, partially changed moss-like, and distributed symmetrically, a wax dropping phenomenon and a film phenomenon can be seen, Auspitz is positive, and the powder has no erosion, exudation and cracks. Pale tongue with thin and white coating and thready and rapid pulse. And (3) diagnosis: psoriasis (syndrome of wind-dryness due to blood deficiency). The preparation of example 3 was applied to the affected area by external washing and wet application for 3 times a day, and 10 days was 1 course of treatment. Taking 800mL of the preparation each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 35-40 ℃, dipping the liquid medicine by using a towel, and washing the liquid medicine for tens of times repeatedly, wherein each time of washing is 15-20 minutes; after washing, 30mL of the preparation is prepared, 5-8 layers of sterile gauze are placed in liquid medicine at the temperature of 4-15 ℃ to be completely soaked, the liquid medicine is squeezed out of the liquid medicine, the liquid medicine is applied to the parts with serious skin damage, and the liquid medicine is frequently sprayed on compress cloth to keep moisture for 15-20 minutes each time. After 10 days, the skin lesion is removed, white scales fall off, and pruritus is relieved, and the preparation is used for 2 treatment courses to consolidate the treatment, so that the whole body is obviously improved, dark red plaques are left, the skin is smooth, and the pruritus is avoided.

Five typical cases:

the patient was examined for initial diagnosis in 10 months and 11 days in 2016. The patients do not have obvious inducement to the head before complaint for 5 days, red papules, maculopapules and scales appear on the trunk and the limbs, the red papules, the maculopapules and the scales gradually spread to the whole body, the silvery white scales are attached on the trunk and the limbs, the patients feel pruritus and are diagnosed with psoriasis when going to a doctor in Kunlua hospital, the patients are orally taken and externally applied to treat psoriasis (the details are not detailed), the symptoms are not obviously relieved, and the patients are seen when going to the doctor: the whole body is scattered on the erythema, and is covered with a thick layer of silvery white scales, so that the elbow and the lower limbs are more severe, the itching is difficult to endure, the scales are distributed symmetrically, the phenomena of wax dropping and film forming can be seen, the Auspitz sign is positive, and the red skin is free from erosion, exudation and cracks. Pale with little coating and deep and thready pulse. And (3) diagnosis: psoriasis (syndrome of wind-dryness due to blood deficiency). The preparation of this example 4 was applied to the affected area by external washing and wet application for 3 times a day, and 5 days were 1 course of treatment. Taking 800mL of the preparation each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 35-0 ℃, dipping the liquid medicine by using a towel, and washing the liquid medicine for tens of times repeatedly, wherein each time of washing is 15-20 minutes; after washing, taking 30mL of the preparation, putting 5-8 layers of sterile gauze into liquid medicine at the temperature of 4-15 ℃ for completely soaking, extruding out redundant liquid medicine, applying the liquid medicine to the serious part of the skin lesion, frequently spraying the liquid medicine on compress for moisturizing, and each time lasts for 15-20 minutes. After 3 days of treatment, the subjective pruritus is relieved, after 5 days of re-diagnosis, the skin damage color becomes light, the white scales partially fall off, the whole skin damage is obviously improved after 2 treatment courses of the preparation, the white scales basically fall off, the elbow and the two lower limbs are still scattered in light red plaques, and the whole skin damage is completely removed as before after the preparation is used for half a month.

Typical cases are six:

patient Liu Yi, female, 47 years old, 2016, 3 months and 10 days for initial diagnosis. The patients have long-term history of external hormone, the face becomes red, scorching and itchy and painful before 3 months, the patients are treated by K8 laser water replenishing before going to the outside hospital and are treated by external Weinuonan allergy-relieving moisturizing cream and the like, the improvement is not obvious, and the patients are seen when coming to a clinic: redness, burning, itching, dryness with little desquamation, tense feeling of facial skin, no weeping, blister, erosion and ulcer, convenient adjustment, easy sleep, red tongue with yellow coating, and rapid pulse. And (3) diagnosis: wind-damp sores (wind-heat accumulation in the skin). The cape jasmine elm lotion is applied to the affected part for external washing and cold wet compress, 1 day is 3 times, and 5 days is 1 course of treatment. Taking 200mL of the preparation of the embodiment 2 each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 15-20 ℃, dipping the liquid medicine by using a towel, and washing for tens of times repeatedly, wherein each washing time is 10-15 minutes; after washing, taking 30mL of the preparation, putting 5-8 layers of sterile gauze into liquid medicine at the temperature of 4-15 ℃ for completely soaking, extruding out redundant liquid medicine, applying the liquid medicine on the face, frequently spraying the liquid medicine on compress cloth for moisturizing, and each time for 15-20 minutes. After 5 days of treatment, the redness of the face is relieved, the burning and itching feeling is relieved, the redness of the face is basically relieved after 2 courses of treatment by using the preparation, the burning, itching and tightness feeling are completely eliminated, and the half-moon treatment is continued to consolidate the curative effect. After 3 months of follow-up, no recurrence was observed.

Seven typical cases:

the patient was initially diagnosed in 2016, 4 and 15 days for 40 years old. The patient complains that erythema and pruritus appear on the face due to the use of cosmetics such as Korean beam, botanic doctors and Eriya before 6 months, the patient is called to visit a local clinic, the diagnosis is that the erythema and pruritus are relieved after the administration of infusion and oral medicines (not detailed) for diagnosis of allergic dermatitis, but the allergic dermatitis is recurrent, no obvious inducement exists before 10 days, the symptoms reappear and aggravate, the symptoms are not relieved after the oral administration of the loratadine tablet, and the patient comes to visit: the face becomes bright red and red, accompanied with pruritus and scorching heat, even after being heated, without scratch, scabbing, seepage, blister, erosion and ulcer, and the people can conveniently adjust the health and sleep. A red tongue with a prick, a thin and yellow coating and a rapid pulse. A red tongue with yellow coating and a rapid pulse. And (3) diagnosis: wind-damp sores (syndrome of heat-toxicity entering nutrient). The preparation of this example 2 was applied to the affected area by external washing and cold-wet application for 3 times in 1 day, and 1 course of treatment was 5 days. Taking 200mL of the preparation each time, adding warm water of which the volume is 3 times of that of the preparation for dilution, controlling the water temperature to be 15-20 ℃, dipping the liquid medicine by using a towel, and washing for tens of times repeatedly, wherein each time of washing is 10-15 minutes; after washing, taking 30mL of the preparation, putting 5-8 layers of sterile gauze into liquid medicine at the temperature of 4-15 ℃ for completely soaking, extruding out redundant liquid medicine, applying the liquid medicine on the face, frequently spraying the liquid medicine on compress cloth for moisturizing, and each time for 15-20 minutes. After 5 days of treatment, the erythema on the face subsides, the burning sensation and the itching sensation are relieved, the erythema on the face basically disappears after 2 courses of treatment by using the preparation, the discomfort such as burning sensation and the itching sensation completely disappears, and the half-moon treatment is continued to consolidate the curative effect. After 3 months of follow-up, no recurrence was observed.

Eight typical cases:

zhangzhi, male, 30 years old, and initial diagnosis 5 months at 2015. The scalp of a patient is itchy for half a year, the rash is greasy scales, and a large amount of scales fall off when the patient combs the head, and the scalp is light and heavy. The diagnosis is seborrheic dermatitis of scalp. The formulation of example 3 was given an external wash 2 times a day for half a month for 1 treatment period. Taking 200mL of the preparation each time, adding warm water of 3 times for dilution, controlling the water temperature at 40-45 ℃, dipping the liquid medicine by a towel, and washing for tens of times repeatedly, wherein each time is 10-15 minutes; after half a month, scalp itch and rash both disappeared. The treatment is continued for half a month to consolidate the effect. After 3 months of follow-up, no recurrence was observed.

After the cure of the above-mentioned several patients, the inventors performed follow-up investigation on them, and the results of the investigation were as follows:

after 3 months of follow-up, 8 patients had no relapse.

After 6 months of follow-up, 8 patients had no relapse.

Therefore, the traditional Chinese medicine preparation prepared by the invention has obvious treatment effect on skin diseases which are easy to relapse, such as eczema, psoriasis and the like, and not only has high cure rate, low relapse rate and small irritation, but also has no toxic or side effect after long-term use.

Claims

1. The traditional Chinese medicine external preparation for treating eczema and psoriasis is characterized by being prepared from the following raw material medicines in parts by weight: 25-50 parts of radix sophorae flavescentis, 25-50 parts of fructus kochiae, 20-40 parts of cortex dictamni, 20-40 parts of raw rhubarb, 20-40 parts of purslane, 10-30 parts of divaricate saposhnikovia root, 10-30 parts of herba schizonepetae, 5-20 parts of alum, 8-15 parts of fructus cnidii, 20-40 parts of garden burnet root, 5-20 parts of cape jasmine fruit and 20-40 parts of herba siegesbeckiae.

2. The traditional Chinese medicine external preparation for treating eczema and psoriasis according to claim 1 is characterized by being prepared from the following raw material medicines in parts by weight: 30 parts of radix sophorae flavescentis, 30 parts of fructus kochiae, 30 parts of cortex dictamni, 30 parts of raw rhubarb, 30 parts of purslane, 20 parts of divaricate saposhnikovia root, 20 parts of fineleaf schizonepeta herb, 10 parts of alum, 10 parts of common cnidium fruit, 30 parts of garden burnet root, 10 parts of cape jasmine fruit and 30 parts of siegesbeckia herb.

3. The preparation method of the external traditional Chinese medicine preparation for treating eczema and psoriasis according to claim 1, which is characterized by comprising the following steps:

① preparing materials, namely weighing various raw materials according to the weight part of the raw rhubarb of claim 1, removing impurities, crushing the raw rhubarb into raw rhubarb powder for later use, slicing and mixing the rest of radix sophorae flavescentis, fructus kochiae, cortex dictamni, purslane, radix sileris, schizonepeta, fructus cnidii, garden burnet, gardenia and herba siegesbeckiae for later use, wherein the purslane and the schizonepeta are dried stems and leaves, the cortex dictamni is dried root bark, the fructus kochiae, gardenia and fructus cnidii are dried mature fruits, the garden burnet, the radix sileris and the radix sophorae flavescentis are dried roots, the raw rhubarb is dried roots and rhizomes, the herba siegesbeckiae is dried whole grass, the particle size of the raw rhubarb powder is smaller than 24 meshes, and the powder with the particle size of 50 meshes or less is not more than 40;

②, percolating, namely putting the raw rhubarb powder crushed in the step ① into cold water for infiltrating, wherein the amount of the cold water is 2-2.5 times of the mass of the raw rhubarb powder, infiltrating for 7-8 hours, adding alum into the infiltrated raw rhubarb powder, adding hot water at the temperature of 70-80 ℃, wherein the amount of the hot water is 9-10 times of the total mass of the raw rhubarb powder and the alum, stirring until the alum is completely dissolved in the hot water, naturally cooling the mixture, and percolating after the mixture is naturally cooled to obtain percolate, wherein the percolating flow rate of the percolating is controlled to be 2400-2500 mL/h;

③ decocting, namely soaking the radix sophorae flavescentis, the fructus kochiae, the cortex dictamni, the purslane, the radix sileris, the herba schizonepetae, the fructus cnidii, the garden burnet, the cape jasmine and the herba siegesbeckiae which are sliced and mixed in the step ① in cold water, wherein the amount of the cold water is 2-3 times of the total mass of the mixture, the cold water is used for soaking for 1-2 hours, then decocting with slow fire, filtering for 1.5-2 hours, collecting primary filtrate for later use, adding the filter residue obtained by primary filtration into cold water 4-5 times of the mass of the filter residue for decoction, filtering for 1-1.5 hours again to obtain secondary filtrate, mixing the primary filtrate and the secondary filtrate uniformly, standing for 8-10 hours, filtering again to remove precipitates, and obtaining the filtrate which is concentrated solution obtained after the decoction and concentration;