CN103127483B

CN103127483B - External-application medicine used for treating vasculitis, and preparation method thereof

Info

Publication number: CN103127483B
Application number: CN201310058312.3A
Authority: CN
Inventors: 杨凤国
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-02-25
Filing date: 2013-02-25
Publication date: 2014-11-05
Anticipated expiration: 2033-02-25
Also published as: CN103127483A

Abstract

The invention relates to an external-application medicine used for treating vasculitis, and a preparation method thereof. The medicine is prepared from the raw materials of, by weight, 7-10 parts of Japanese thistle, 6-9 parts of common thistle, 1-2.5 parts of ligusticum, 2-5 parts of argy wormwood leaf, 32-58 parts of fresh ginger, 2-5 parts of xanthium strumarium, 0.2-0.5 parts of castor oil, 0.56-0.86 parts of capparis spinosa, 2-5 parts of speranskia tuberculata, 5-8 parts of imperatae rhizome, and 1-2.5 parts of drug sweetflag rhizome. With the medicine, vasculitis can be effectively treated. The medicine has the effects of heat clearing, detoxifying, meridian warming, cold dispelling, and body injury repairing. The medicine has low toxic and side effects, and has low cost. The medicine provides a good curative effect.

Description

A kind of vasculitic application compress and preparation method thereof for the treatment of

Technical field

The present invention relates to a kind of vasculitic application compress and preparation method thereof for the treatment of.

Background technology

Vasculitis is that thromboangiitis obliterans is called for short.A kind of chronic sustained, the progressive vascular inflammation pathological changes that refer to vascular around (in, small artery and vein), cause thrombosis to make lumen of vessels inaccessible.In northern China, each province is common.Be mainly in male person between twenty and fifty.Pathological changes mainly involve distal limbs in, small artery, accompanying vein and Superficial veins also often involve, and take lower limb as main.Clinical main manifestations is the skin color of sick lower limb vein and temperature change, intermittent claudication, stationary pain, and severe patient can complicated by ulcer, gangrene.

Primary disease is equivalent to the categories such as Chinese medicine necrosis, gangrene of toe.Its sick endogenous cause of ill is mainly deficiency-weakness of spleen-QI, deficiency of the liver and kindey; Exopathogenic factor is mainly cold-damp invasion and attack, and long-term smoking is also the occurrence factor of facilitating primary disease.Primary disease is many, and because of deficiency of spleen-YANG and kidneyYANG, cold-damp is invaded outward, cold-damp cohesion passages through which vital energy circulates; Or because of feelings will internal injury, internal organs intrinsic heat, pathogenic heat are excessive causes venation numbness plug in venation etc., and QI and blood is inconsiderate to be formed.

Modern medicine there is no unified understanding so far to vasculitic pathogeny, it is generally acknowledged, how closely relevant with sympathetic nerve function disorder and autoimmune response etc., its treatment remains a great problem medically.Current, the related surgicals such as the treatment normal hyperbaric oxygentherapy of vasculitis or employing lumbar sympathectomy, arterial thrombus Endarterectomy and arterial bypass are treated.The hyperbaric oxygentherapy cycle is long, and recovery time is slow, and therapeutic effect is poor; Operative treatment not only make human organ and normal cell impaired, and can increase patient's misery, the convalescence after Miles operation is slow, relapse rate is high, easily causes thrombosis to cause Other diseases, therapeutic effect is also undesirable; Radiation and Western medicine are except expensive, and side effect is also larger, make human organ and normal cell impaired, and curative effect can not be satisfactory.

Summary of the invention

The object of this invention is to provide a kind of vasculitic application compress and preparation method thereof for the treatment of, can effectively to vasculitis, treat, there is the effect of heat-clearing and toxic substances removing, dispelling cold by warming the meridian, reparation body injury, and toxic and side effects be little, cost is low, has good rehabilitation efficacy.

For this reason, the present invention is the medicine of being made by the raw material of following weight proportioning:

1～2.5 part of 6～9 parts of Radix Angelicae Sinensis of 7～10 portions of Herba Cirsiis of Radix Cirsii Japonici

2～5 parts of 32～58 portions of Herba Xanthiis of 2～5 parts of fresh gingers of Folium Artemisiae Argyi

2～5 parts of 0.56～0.86 part of Herba speranskiae tuberculataes of 0.2～0.5 part of Herba hibisci trioni of Oleum Ricini

1～2.5 part of 5～8 parts of Rhizoma Acori Calami of Rhizoma Imperatae.

The preferably weight proportion of each raw material of the present invention is:

1～2 part of 6.5～8 parts of Radix Angelicae Sinensis of 8～9 portions of Herba Cirsiis of Radix Cirsii Japonici

2～4 parts of 35～49 portions of Herba Xanthiis of 2～4 parts of fresh gingers of Folium Artemisiae Argyi

2～4 parts of 0.6～0.7 part of Herba speranskiae tuberculataes of 0.2～0.4 part of Herba hibisci trioni of Oleum Ricini

1～2 part of 6～7 parts of Rhizoma Acori Calami of Rhizoma Imperatae.

The weight proportion of best each raw material of formula of the present invention is:

1.5 parts of 7 parts of Radix Angelicae Sinensis of 8 portions of Herba Cirsiis of Radix Cirsii Japonici

3 parts of 41 portions of Herba Xanthiis of 3 parts of fresh gingers of Folium Artemisiae Argyi

3 parts of 0.66 part of Herba speranskiae tuberculataes of 0.3 part of Herba hibisci trioni of Oleum Ricini

1.5 parts of 6 parts of Rhizoma Acori Calami of Rhizoma Imperatae.

A preparation method of preparing these application compress, comprises the steps:

(1) take off the raw material of stating weight proportion: 7～10 parts of Radix Cirsii Japonicis, 6～9 parts of Herba Cirsiis, 2～5 parts of Folium Artemisiae Argyis, 32～58 parts of fresh gingers, 2～5 parts of Herba Xanthiis, 0.2～0.5 part of Oleum Ricini, 0.56～0.86 part of Herba hibisci trioni, 2～5 parts of Herba speranskiae tuberculataes, 5～8 parts of Rhizoma Imperatae, 1～2.5 part of Rhizoma Acori Calami;

(2) by Radix Cirsii Japonici, Herba Cirsii, Folium Artemisiae Argyi, Herba Xanthii, Herba hibisci trioni, Herba speranskiae tuberculatae, Rhizoma Imperatae, that Rhizoma Acori Calami is ground into powder is planar, add Oleum Ricini mix homogeneously, fresh ginger is pulverized, add wherein, mix homogeneously, the water content that makes above-mentioned mixed powder is 40～45%, moisture deficit adds white vinegar and mends, be mixed, make mixing spice;

(3) mixing spice is inserted in steamer, steam 30～50 minutes, take out and mix spice, add the Herba hibisci trioni of pulverizing when its temperature is down to 60～70 ℃, mix homogeneously, packs, and obtains finished medicines;

(4) while using; finished medicines is heated to 45～50 ℃; on skin outside patient's diseased region, paste the husky cloth of one deck; at husky cloth, apply the finished medicines after heating again; medicine layer thickness 0.5～1.2cm; at 1～3 layer of husky cloth of this medicine layer outer wrapping, with rope tighten, outermost layer wraps with Polypropylence Sheet or mackintosh again; Application time 5～12 hours, 12～15 days, twice application time interval.Pasting medicine 3 is a course for the treatment of.

Described white vinegar is that every 100ml is 5～6g containing total acid.

Solution of the present invention is the rule to vasculitis disease according to the traditional Chinese medical science, i.e. blood circulation promoting and blood stasis dispelling, and eliminating stasis to stop pain, the dredging collateral of enriching blood, bactericidal antiphlogistic, clearing away damp-heat, rushes down poison fire, counteracting toxic substances, eliminating stagnation.The present invention forms according to above-mentioned rule, can blood circulation promoting and blood stasis dispelling, and eliminating stasis to stop pain, clearing away damp-heat, rushes down poison fire, and counteracting toxic substances, eliminating stagnation again can eliminating stasis to stop pain, the dredging collateral of enriching blood.Radix Cirsii Japonici in the present invention, cool in nature, sweet in the mouth, has removing heat from blood, hemostasis, blood stasis dispelling, the effect of subduing inflammation.Herba Cirsii, nature and flavor are sweet, cool, have removing heat from blood, blood stasis dispelling, the effect of hemostasis, energy vasoconstrictive, shortening clotting time, all have inhibitory action to Diplococcus pneumoniae, Hemolytic streptococcus, diphtheria corynebacterium, typhoid fever village bacterium, bacillus pyocyaneus, dysentery bacterium, staphylococcus aureus etc.Radix Angelicae Sinensis, nature and flavor are sweet, warm, have adjusting body's immunity, enrich blood and invigorate blood circulation, the effect of antibacterial and arteriosclerosis.Folium Artemisiae Argyi, nature and flavor are pungent, warm, energy dispersing cold for relieving pain, warming the meridian for stopping bleeding, reasonable QI and blood, by the effect of cold-damp.Fresh ginger, nature and flavor are pungent, warm, have to deliver, cold expelling, preventing or arresting vomiting, open the effect of expectorant.Herba Xanthii, nature and flavor toil, cold, poisonous, has wind and heat eliminating, the effect of removing toxic substances parasite killing.Oleum Ricini, nature and flavor are sweet, pungent, have loosening bowel to relieve constipation, the effect of heat-clearing and toxic substances removing.Herba hibisci trioni, nature and flavor are sweet, cold, have expelling wind and cold, the effect of dehumidifying.Herba speranskiae tuberculatae, nature and flavor are sweet, and have and dispel the wind, dehumidifying, relaxing muscles and tendons, invigorates blood circulation, the effect of pain relieving.Rhizoma Imperatae, nature and flavor are sweet, cool, have removing heat from blood, hemostasis, heat clearing away, the effect of diuresis.Rhizoma Acori Calami, warm in nature, acrid in the mouth, flat, bitter, have have one's ideas straightened out, reduce phlegm, stomach invigorating, refreshment, have the effect of clearing away damp-heat.The present invention has eliminating evil just wound, righting and do not stay heresy, warm network blood stasis dispelling, calm the nerves, a surname's gas is had one's ideas straightened out, loose strongly fragrant eliminating phlegm, subduing swelling and detoxicating, bactericidal antiphlogistic, the dredging collateral of enriching blood, has the vasculitic effect of good treatment, in hundreds of vasculitis patients for the treatment of, cure rate is 68%, and obvious effective rate reaches 85%, and improvement rate reaches more than 98%.(evaluation criteria, cures: cardinal symptom disappears, and wound heals completely, and suffering limb disturbance of blood circulation is alleviated or obviously improved, and resumes work in 1 year without recurrence.Effective: clinical symptoms is most of to disappear or significantly alleviates, and rest pain disappears, and skin temperature and color and luster are clearly better, wound healing or approach healing, blood circulation is slight obstacle, can work.Take a turn for the better: condition of illness alleviates, and wound surface before dwindles, suffering limb circulation makes moderate progress, and still can not be engaged in work.Invalid: through treatment in 1～3 month, clinical symptoms and sign were all without improving, even increase the weight of.)

Of the present invention one the course for the treatment of cost be only 20% of the traditional same vessel scorching course for the treatment of of cost, can greatly save patient's expense expenditure.

The present invention be medicine for external use to human viscera organ without injury, drug safety.The pain in the lumbar region that the present invention is caused by diseases such as blood stasis other, have a pain in the leg, cervical vertebra pain patient also has certain curative effect, cure, effective and improvement rate is in 80% left and right.

Model case: *, man, 38 years old.First visit, private prosecution right leg to foot sends out pain cool, intermittent claudication 9 months, look into right sufficient little toe end ulcer, before February, started right heel to toes first half and toes pain, after there is again the swollen pain of walking gaskin tripe, after rest, alleviate, look into right leg place varicosis and protrude, be intermittent claudication and go through more than May.State of an illness day is heavy, and first quarter moon front right foot little toe toe-end forms ulcer, and sharp ache, lies awake all night.Patient is peasant, makes moist for a long time raw cold.Check: shallow complexion, body is thin, and right sufficient little toe end ulcer is 1.2 * 0.8cm approximately, a little yellow secretions, slough is not de-.The dim purple in instep, right foot is sent out cool, and dorsal artery of foot still can stereognosis.Right leg place varicosis is protruded, the sliding number of pulse condition.Diagnosis: thromboangiitis obliterans.Use application compress of the present invention after the course for the treatment of, cardinal symptom disappears, and ulcer wound heals completely, and instep color is normal, sleep, body weight increases 4Kg, and suffering limb disturbance of blood circulation obviously improves, it is normal that the vein that varicose is protruded recovers, resume work in 2 years without recurrence, and recovery from illness.

The specific embodiment

Treat vasculitic application compress, it is the medicine of being made by the raw material of following weight proportioning: 7～10 parts of Radix Cirsii Japonicis, 6～9 parts of Herba Cirsiis, 1～2.5 part of Radix Angelicae Sinensis, 2～5 parts of Folium Artemisiae Argyis, 32～58 parts of fresh gingers, 2～5 parts of Herba Xanthiis, 0.2～0.5 part of Oleum Ricini, 0.56～0.86 part of Herba hibisci trioni, 2～5 parts of Herba speranskiae tuberculataes, 5～8 parts of Rhizoma Imperatae, 1～2.5 part of Rhizoma Acori Calami.

Embodiment 1: by following proportioning, take raw material: Radix Cirsii Japonici 8kg, Herba Cirsii 7kg, Radix Angelicae Sinensis 1.5kg, Folium Artemisiae Argyi 3kg, fresh ginger 41kg, Herba Xanthii 3kg, Oleum Ricini 0.3kg, Herba hibisci trioni 0.66kg, Herba speranskiae tuberculatae 3kg, Rhizoma Imperatae 6 kg, Rhizoma Acori Calami 1.5kg.

Preparation method is: the raw material of getting above-mentioned weight proportion, by Radix Cirsii Japonici, Herba Cirsii, Folium Artemisiae Argyi, Herba Xanthii, Herba hibisci trioni, Herba speranskiae tuberculatae, Rhizoma Imperatae, that Rhizoma Acori Calami is ground into powder is planar, add Oleum Ricini mix homogeneously, fresh ginger is pulverized, add wherein mix homogeneously, the water content that makes above-mentioned mixed powder is 40～45%, moisture deficit adds white vinegar mends, and is mixed, and makes mixing spice.Mixing spice is inserted in steamer, steam 30～50 minutes, take out and mix spice, add the Herba hibisci trioni of pulverizing when its temperature is down to 60～70 ℃, mix homogeneously, packs, and obtains finished medicines.Described white vinegar is that every 100ml is 5～6g containing total acid.

During use; finished medicines is heated to 45～50 ℃; on skin outside patient's diseased region, paste the husky cloth of one deck; at husky cloth, apply the finished medicines after heating again; medicine layer thickness 0.5～1.2cm; at 1～3 layer of husky cloth of this medicine layer outer wrapping, with rope tighten, outermost layer wraps with Polypropylence Sheet or mackintosh again; Application time 5～12 hours, 12～15 days, twice application time interval.

Embodiment 2: by following proportioning, take raw material: Radix Cirsii Japonici 9kg, Herba Cirsii 6kg, Radix Angelicae Sinensis 1kg, Folium Artemisiae Argyi 5kg, fresh ginger 48kg, Herba Xanthii 5kg, Oleum Ricini 0.5kg, Herba hibisci trioni 0.86kg, Herba speranskiae tuberculatae 2kg, Rhizoma Imperatae 8kg, Rhizoma Acori Calami 2.5kg.

Preparation and application, with embodiment 1.

Embodiment 3: by following proportioning, take raw material: Radix Cirsii Japonici 7kg, Herba Cirsii 8kg, Radix Angelicae Sinensis 1.2kg, Folium Artemisiae Argyi 2kg, fresh ginger 44kg, Herba Xanthii 5kg, Oleum Ricini 0.5kg, Herba hibisci trioni 0.86kg, Herba speranskiae tuberculatae 2kg, Rhizoma Imperatae 8kg, Rhizoma Acori Calami 2.5kg.

Method for making and usage, with embodiment 1.Therefore be not repeated.

In a word, the present invention can treat vasculitis effectively, have the effect of heat-clearing and toxic substances removing, dispelling cold by warming the meridian, reparation body injury, and toxic and side effects is little, and cost is low, has good rehabilitation efficacy.

Claims

1. treat vasculitic application compress, it is characterized in that: it is the medicine of being made by the raw material of following weight proportioning:

1～2.5 part of 5～8 parts of Rhizoma Acori Calami of Rhizoma Imperatae.

2. a kind of vasculitic application compress for the treatment of according to claim 1, is characterized in that: wherein the weight proportion of each raw material is:

1～2 part of 6～7 parts of Rhizoma Acori Calami of Rhizoma Imperatae.

3. a kind of vasculitic application compress for the treatment of according to claim 1, is characterized in that: wherein the weight proportion of each raw material is:

1.5 parts of 6 parts of Rhizoma Acori Calami of Rhizoma Imperatae.