CN104430492B - A kind of bactericidal composition containing thifluzamide and Silthiopham - Google Patents
A kind of bactericidal composition containing thifluzamide and Silthiopham Download PDFInfo
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- CN104430492B CN104430492B CN201410588980.1A CN201410588980A CN104430492B CN 104430492 B CN104430492 B CN 104430492B CN 201410588980 A CN201410588980 A CN 201410588980A CN 104430492 B CN104430492 B CN 104430492B
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- China
- Prior art keywords
- silthiopham
- thifluzamide
- bactericidal composition
- bactericidal
- sheath blight
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- WOSNCVAPUOFXEH-UHFFFAOYSA-N thifluzamide Chemical compound S1C(C)=NC(C(F)(F)F)=C1C(=O)NC1=C(Br)C=C(OC(F)(F)F)C=C1Br WOSNCVAPUOFXEH-UHFFFAOYSA-N 0.000 title claims abstract description 40
- MXMXHPPIGKYTAR-UHFFFAOYSA-N silthiofam Chemical compound CC=1SC([Si](C)(C)C)=C(C(=O)NCC=C)C=1C MXMXHPPIGKYTAR-UHFFFAOYSA-N 0.000 title claims abstract description 39
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 18
- 239000000203 mixture Substances 0.000 title claims description 27
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 17
- 201000010099 disease Diseases 0.000 claims abstract description 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 16
- 235000009566 rice Nutrition 0.000 claims abstract description 15
- 230000000694 effects Effects 0.000 claims abstract description 14
- 208000031888 Mycoses Diseases 0.000 claims abstract description 5
- 239000003899 bactericide agent Substances 0.000 claims abstract description 5
- 240000007594 Oryza sativa Species 0.000 claims abstract description 4
- 239000004563 wettable powder Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 239000004562 water dispersible granule Substances 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000007900 aqueous suspension Substances 0.000 claims description 2
- 239000002131 composite material Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 12
- 206010059866 Drug resistance Diseases 0.000 abstract description 4
- 244000052769 pathogen Species 0.000 abstract description 4
- 230000001717 pathogenic effect Effects 0.000 abstract description 4
- 244000052616 bacterial pathogen Species 0.000 abstract description 3
- 230000003111 delayed effect Effects 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 3
- 241001465754 Metazoa Species 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000007423 decrease Effects 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 231100000053 low toxicity Toxicity 0.000 abstract description 2
- 241000209094 Oryza Species 0.000 description 13
- 238000002360 preparation method Methods 0.000 description 12
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 9
- 239000013530 defoamer Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- -1 seed treatment Substances 0.000 description 6
- 229910019142 PO4 Inorganic materials 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 5
- 239000010452 phosphate Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 4
- 239000000375 suspending agent Substances 0.000 description 4
- LWEAHXKXKDCSIE-UHFFFAOYSA-M 2,3-di(propan-2-yl)naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S([O-])(=O)=O)=C(C(C)C)C(C(C)C)=CC2=C1 LWEAHXKXKDCSIE-UHFFFAOYSA-M 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- 235000012211 aluminium silicate Nutrition 0.000 description 3
- 150000001412 amines Chemical class 0.000 description 3
- 239000007859 condensation product Substances 0.000 description 3
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 239000000230 xanthan gum Substances 0.000 description 3
- 229920001285 xanthan gum Polymers 0.000 description 3
- 229940082509 xanthan gum Drugs 0.000 description 3
- 235000010493 xanthan gum Nutrition 0.000 description 3
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 235000007340 Hordeum vulgare Nutrition 0.000 description 2
- 240000005979 Hordeum vulgare Species 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 229920005551 calcium lignosulfonate Polymers 0.000 description 2
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- ZEMPKEQAKRGZGQ-AAKVHIHISA-N 2,3-bis[[(z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (z)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCCC(O)C\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CC(O)CCCCCC)COC(=O)CCCCCCC\C=C/CC(O)CCCCCC ZEMPKEQAKRGZGQ-AAKVHIHISA-N 0.000 description 1
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
- QOYXIHSMOOWKSF-XXAVUKJNSA-N CNCC[Na].C(CCCCCCC\C=C/CCCCCCCC)(=O)O Chemical compound CNCC[Na].C(CCCCCCC\C=C/CCCCCCCC)(=O)O QOYXIHSMOOWKSF-XXAVUKJNSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 229940124186 Dehydrogenase inhibitor Drugs 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000813090 Rhizoctonia solani Species 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
- OYVABZRZDZPVQD-UHFFFAOYSA-N [F].C=1C=CSC=1 Chemical compound [F].C=1C=CSC=1 OYVABZRZDZPVQD-UHFFFAOYSA-N 0.000 description 1
- TWWCNXGLDZPFQV-XXAVUKJNSA-N [Na].CNCCS(=O)(=O)O.C(CCCCCCC\C=C/CCCCCCCC)(=O)O Chemical compound [Na].CNCCS(=O)(=O)O.C(CCCCCCC\C=C/CCCCCCCC)(=O)O TWWCNXGLDZPFQV-XXAVUKJNSA-N 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 238000000498 ball milling Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000010413 mother solution Substances 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- KXRSDCFOWWZZPE-UHFFFAOYSA-N silicon;thiophene Chemical compound [Si].C=1C=CSC=1 KXRSDCFOWWZZPE-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of new type bactericide compositionss containing thifluzamide and Silthiopham, which includes mass ratio for 15：1～1：15 active component thifluzamide and Silthiopham.The present invention has preferable prevention effect to the crop fungal disease such as rice sheath blight disease, and the combination of two medicaments can reduce dosage, effectively reduce ecological disruption and environmental pollution, and can improve crop yield and quality；In the present invention, thifluzamide and Silthiopham belong to low toxicity, to people and animals, beneficial organism safety；Drug resistance of the pathogenic bacteria to single medicament can be delayed.Thifluzamide is combined by a certain percentage with Silthiopham, have bactericidal activity high in actual use, selection pressure that thifluzamide and Silthiopham single dose when being used alone to pathogen cause is avoided simultaneously to a greater extent can, pathogen Drug resistance is delayed to produce and develop, and decline dosage total in unit area, economic, efficient, environmental protection.
Description
Technical field
The invention belongs to disinfectant use in agriculture field, and in particular to the bactericidal composition of a kind of thifluzamide and Silthiopham.
Background technology
Thifluzamide is called thiophene fluorine bacterium amine（English name：Thifluzamide molecular formula are C13H6Br2F6N2O2S, structure
Formula is as follows：
Chemical name：Bis- bromo- 2- methyl -4'- trifluoromethoxy -4- Trifluoromethyl-1s of 2', 6'-, 3- thiadiazoles -5- hydroxyl acyls
Aniline;, its mechanism of action thifluzamide is succinate dehydrogenase inhibitor, and in suppressing pathogenic bacteria tricarboxylic acid cycle, succinic acid goes
Hydrogen enzyme, causes thalline dead.It has very strong Uptake and translocation performance, can be with the side such as foliar spray, seed treatment, soil treatment
Formula apply, have good prevention effect to many kinds of fungal diseases, can be widely applied to Oryza sativa L., wheat and barley, Semen arachidis hypogaeae, Cotton Gossypii,
The various crops such as Radix Betae, coffee, Rhizoma Solani tuber osi, lawn.It is mainly used in preventing and treating the banded sclerotial blight of Oryza sativa L. and wheat and barley in production.
Silthiopham（English common name： silthiopham ）, molecular formula is C13H21NOSSi, and structural formula is as follows：
Chemical common name be N- pi-allyl -4,5- dimethyl -2- (TMS) thiophene -3- Methanamides, research
Show which is inhibitor of energy：Possibly ATP inhibitor.With good protection activity, the longevity of residure is long.It is complete for preventing and treating Semen Tritici aestivi
Erosion disease, using method mainly makees seed treatment, seed dressing can strong inhibition take-all.
The content of the invention
It is an object of the invention to provide a kind of new type bactericide compositionss containing thifluzamide and Silthiopham, for preventing
Control the various crop disease such as rice sheath blight disease.Thifluzamide possesses different structure types and discrepant effect from Silthiopham
Mechanism, the two is combined by a certain percentage, high with bactericidal activity in actual use, while can avoid to a greater extent
The selection pressure that thifluzamide and Silthiopham single dose are caused to pathogen when being used alone, delay pathogen Drug resistance produce and
Development, and decline dosage total in unit area, economic, efficient, environmental protection.
A kind of bactericidal composition containing thifluzamide and Silthiopham of the present invention, includes mass ratio for 15：1～1：15
Active component thifluzamide and Silthiopham.
Preferably, the mass ratio of the thifluzamide and Silthiopham is 10：1～1：10；It is furthermore preferred that the thiophene furan acyl
The mass ratio of amine and Silthiopham is 5：1～1：1.
Bactericidal composition of the present invention is added with conventional agricultural bactericidal agent aid and makes agriculturally conventional sterilization
Combination dosage form, described bactericidal composition dosage form can be aqueous suspension agent, wettable powder or water-dispersible granules.Using
Agricultural bactericidal agent aid includes each analog assistant such as wetting agent, dispersant, thickening agent, defoamer, filler, the wetting agent of employing, point
Powder can be alkylnaphthalene sulfonate formaldehyde condensation products, nekal（Pull open powder）, Oleic acid methylaminoethyl sulfonic acid
Sodium, sodium lignin sulfonate, calcium lignosulfonate, alkylphenol-polyethenoxy base ether, alkylphenol-polyethenoxy base phosphate ester, Oleum Ricini
One or more in polyoxyethylene ether etc.；The thickening agent for adopting can be xanthan gum, polyvinyl alcohol etc.；Using defoamer can
For one or more in phosphoric acid ester defoamer and organic silicon defoamer；The filler for being adopted can be white carbon, Kaolin, concavo-convex
One or more in rod soil etc..
The active component of the thifluzamide and Silthiopham composition accounts for the 10%～60% of bactericidal composition gross mass, preferably
For 10%～40%.
Bactericidal composition of the present invention can be used to prevent and treat the crop fungal diseases such as rice sheath blight disease.
By the careful analysis to thifluzamide and the Silthiopham mechanism of action and sterilization idiocratic, enter with Wadley methods
Row EXPERIMENTAL DESIGN and result treatment.Two single compound of thifluzamide and Silthiopham is determined first（Hereinafter referred to as medicament）'s
EC50, according to the EC of two single medicaments50The portfolio ratio of two medicaments is set by Wadley methods, and according to Wadley potentiation indexes
SR values, it is determined that suitable composition ratio, is then verified by the abundant methods of Sun Yun.
Test objective thing is rice sheath blight disease.Test is using colony diameter method.Thifluzamide, Silthiopham mother solution are taken, is matched somebody with somebody
Being set to needs medicinal liquid flat board, per ware about 14ml, while arrange compareing without medicine flat board（CK）, often process and repeat 3 wares, that is, be repeated 3 times.
The mycelia block of 5mm diameters is produced in the card punch of preculture colony edge sterilizing, is moved on on different culture media flat board respectively, 28
DEG C culture 4d, measure colony diameter（mm）, growth inhibition ratio is calculated by following equation：
Mycelial growth inhibition rate is converted into into suppression probit value（Y）, drug concentration is converted into log concentration（X）, by concentration
Logarithm is abscissa, probit value makees toxicity regression straight line for vertical coordinate, tries to achieve thifluzamide with Silthiopham single dose and its mixture
Virulence regression equation to Rhizoctonia solani Kuhn, and calculate EC50、EC90Value and correlation coefficient r value.
The interaction of mixture is evaluated according to Wadley methods, computing formula is as follows：
EC50 (theoretical values) = (a+b)/(a/EC50a+ b/EC50b), SR=EC50 (theoretical values)/EC50 (actual values) 。
Wherein a, b are each component content ratio in mixture, analyze the effect of mixture with SR values.SR≤0.5, then two kinds of medicines
Agent mixture has antagonism；SR=0.5～1.5, then two kinds of medicament mixtures have addition；SR >=1.5, then two kinds of medicaments are mixed
It is furnished with potentiation.
1 thifluzamide of table is with Silthiopham single dose and its mixture to rice sheath blight disease toxicity test result
Can analyze from data in table 1 and obtain, thifluzamide and Silthiopham are with 15：1～1：Can press down during 15 ratio mixture
The growth of controlling the water circulation sheath and culm blight of rice mycelia, with 1：1 ratio mixture, can show and increase compared with the growth of high inhibition rice sheath blight disease mycelia
Effect is acted on.
The present invention has preferable prevention effect to the crop fungal disease such as rice sheath blight disease, and the combination of two medicaments can reduce use
Dose, effectively reduces ecological disruption and environmental pollution, and can improve crop yield and quality；Thifluzamide and silicon thiophene in the present invention
Bacterium amine belongs to low toxicity, to people and animals, beneficial organism safety；Drug resistance of the pathogenic bacteria to single medicament can be delayed.
Specific embodiment
Following embodiments are further illustrating using as the explaination to the technology of the present invention content for present invention, but
The present invention flesh and blood be not limited in described in following embodiments, one of ordinary skill in the art can with and should know appoint
What simple change or replacement based on true spirit all should belong to protection domain of the presently claimed invention.
Embodiment 1
The preparation method of 33% thifluzamide Silthiopham suspending agent：By mass percentage.
Thifluzamide 30%；
Silthiopham 3%；
Alkylnaphthalene sulfonate formaldehyde condensation products 4%；
Alkylphenol-polyethenoxy base phosphate ester 3%；
Xanthan gum 0.2%；
Organic silicon defoamer 0.4%；
Water surplus.
Preparation method：According to formula, above component is weighed in proportion, add ball mill ball milling 30 minutes, filtered, suction
Dispersion tank high speed shear after 3 minutes Jing sand mills be fully ground, control solid constituent particle diameter within 2 microns, grinding knot
Stir after beam, obtain final product suspending agent product.Every mu of 60-80g is used to prevent and treat rice sheath blight disease effect up to more than 88%.
Embodiment 2
The preparation method of 30% thifluzamide Silthiopham suspending agent：By mass percentage.
Thifluzamide 25%；
Silthiopham 5%；
Sodium lignin sulfonate 7%；
Alkylphenol-polyethenoxy base phosphate ester 5%；
Xanthan gum 0.2%；
Phosphate ester defoamer 0.3%；
Water surplus.
Preparation method, with embodiment 1.Every mu of 60-80g is used to prevent and treat rice sheath blight disease effect up to 76%.
Embodiment 3
The preparation method of 20% thifluzamide Silthiopham suspending agent：By mass percentage.
Thifluzamide 10%；
Silthiopham 10%；
Nekal 6%；
4 % of castor oil polyoxyethylene ether；
Polyvinyl alcohol 0.2%；
Phosphate ester defoamer 0.4%；
Water surplus.
Preparation method, with embodiment 1.Every mu of 60-80g is used to prevent and treat rice sheath blight disease effect up to 80%.
Embodiment 4
The preparation method of 40% thifluzamide Silthiopham wettable powder：By mass percentage.
Thifluzamide 20%；
Silthiopham 20%；
Calcium dodecyl benzene sulfonate 3%
Nekal 4%；
White carbon 10%；
Kaolin surplus；
Preparation method：Comminution by gas stream is carried out after above component is added mixer mix homogeneously by formula proportion, has been crushed
Stir into after, you can obtain wettable powder product.Every mu of 60-80g is reachable for preventing and treating rice sheath blight disease effect
86%。
Embodiment 5
The preparation method of 30% thifluzamide Silthiopham wettable powder：By mass percentage.
Thifluzamide 25%；
Silthiopham 5%；
Alkylnaphthalene sulfonate formaldehyde condensation products 4%
Sodium lignin sulfonate 4%；
White carbon 10%；
Attapulgite surplus
Preparation method, with embodiment 4.Every mu of 60-80g is about 80% for preventing and treating rice sheath blight disease effect.
Embodiment 6
The preparation method of 10% thifluzamide Silthiopham water dispersible granules：By mass percentage.
Thifluzamide 5%；
Silthiopham 5%；
Oleic acid methylaminoethyl sodium sulfonate 5%；
Calcium lignosulfonate 2%；
Polyvinyl alcohol 4%
Ammonium sulfate 8%
White carbon 10%；
Kaolin surplus；
Preparation method：Comminution by gas stream is carried out after above component is added mixer mix homogeneously by formula proportion, has been crushed
A small amount of purified water is added to stir into rear, extruder grain can obtain water dispersible granules product after drying.Every mu of 60-80g
For preventing and treating rice sheath blight disease effect up to 82%.
Claims (3)
1. a kind of bactericidal composition containing thifluzamide and Silthiopham, it is characterised in that：Include mass ratio for 1:1 activity
Component thifluzamide and Silthiopham；It is added with conventional agricultural bactericidal agent aid and makes agriculturally conventional Bactericidal composite agent
Type；Described bactericidal composition dosage form is aqueous suspension agent, wettable powder or water-dispersible granules.
2. bactericidal composition according to claim 1, it is characterised in that：The work of the thifluzamide and Silthiopham composition
Property component accounts for the 10%～60% of bactericidal composition gross mass.
3. the bactericidal composition described in any one of claim 1-2 is used for the crop fungal disease for preventing and treating rice sheath blight disease.
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| CN201410588980.1A CN104430492B (en) | 2014-10-29 | 2014-10-29 | A kind of bactericidal composition containing thifluzamide and Silthiopham |
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| CN105076193A (en) * | 2014-05-21 | 2015-11-25 | 深圳诺普信农化股份有限公司 | Composition containing silthiopham |
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2014
- 2014-10-29 CN CN201410588980.1A patent/CN104430492B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN104430492A (en) | 2015-03-25 |
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