CN104427993B - 用于治疗由缺氧和低气压造成的肺型高山病的药物组合物 - Google Patents

用于治疗由缺氧和低气压造成的肺型高山病的药物组合物 Download PDF

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Publication number
CN104427993B
CN104427993B CN201380033379.XA CN201380033379A CN104427993B CN 104427993 B CN104427993 B CN 104427993B CN 201380033379 A CN201380033379 A CN 201380033379A CN 104427993 B CN104427993 B CN 104427993B
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Prior art keywords
peptide
seq
purposes according
amino acid
peptides
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English (en)
Chinese (zh)
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CN104427993A (zh
Inventor
B.费希尔
R.鲁卡斯
H.费希尔
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Apeptico Forschung und Entwicklung GmbH
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Apeptico Forschung und Entwicklung GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201380033379.XA 2012-06-28 2013-06-19 用于治疗由缺氧和低气压造成的肺型高山病的药物组合物 Active CN104427993B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12173983.3 2012-06-28
EP12173983.3A EP2679239A1 (de) 2012-06-28 2012-06-28 Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
PCT/EP2013/062777 WO2014001177A1 (de) 2012-06-28 2013-06-19 Pharmazeutische zusammensetzung zur behandlung der durch sauerstoffarmut und verringerten luftdruck vermittelten pulmonalen form der höhenkrankheit

Publications (2)

Publication Number Publication Date
CN104427993A CN104427993A (zh) 2015-03-18
CN104427993B true CN104427993B (zh) 2017-03-08

Family

ID=48672620

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CN201380033379.XA Active CN104427993B (zh) 2012-06-28 2013-06-19 用于治疗由缺氧和低气压造成的肺型高山病的药物组合物

Country Status (14)

Country Link
US (2) US9802985B2 (OSRAM)
EP (2) EP2679239A1 (OSRAM)
JP (1) JP6113277B2 (OSRAM)
KR (1) KR102010793B1 (OSRAM)
CN (1) CN104427993B (OSRAM)
AP (1) AP2014008162A0 (OSRAM)
AU (1) AU2013283563B2 (OSRAM)
CA (1) CA2875749C (OSRAM)
EA (1) EA030384B1 (OSRAM)
ES (1) ES2602197T3 (OSRAM)
IN (1) IN2015DN00585A (OSRAM)
MX (1) MX354302B (OSRAM)
PE (1) PE20150198A1 (OSRAM)
WO (1) WO2014001177A1 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015132294A1 (en) * 2014-03-04 2015-09-11 Apeptico Forschung Und Entwicklung Gmbh Attenuation of intrapulmonary inflammation
EP3062772B1 (en) 2014-03-18 2018-01-24 APEPTICO Forschung und Entwicklung GmbH Dry-powder peptide medicament
US11111160B2 (en) 2015-08-25 2021-09-07 Bar-Ilan University Asymmetric electrochemical cell apparatus, and operating methods thereof
US11439869B2 (en) 2017-05-19 2022-09-13 Trudell Medical International Positive expiratory pressure device
USD903097S1 (en) 2018-05-18 2020-11-24 Trudell Medical International Mask
USD874064S1 (en) 2018-05-18 2020-01-28 Trudell Medical International Mask
USD893806S1 (en) 2018-11-09 2020-08-18 Trudell Medical Internationl Mask and shroud
EP4051311A4 (en) * 2019-10-29 2023-12-06 University of Pittsburgh - of the Commonwealth System of Higher Education LUNG-SPECIFIC TARGETING PEPTIDE (LTP), COMPOSITIONS AND RELATED USES
DK4051307T5 (da) 2020-05-08 2024-07-22 Apeptico Forschung & Entwicklung Gmbh Peptid til forebyggelse eller behandling af covid-19

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US4069819A (en) 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
IT1228459B (it) 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
AU6001094A (en) 1993-02-03 1994-08-29 N.V. Innogenetics S.A. Tnf-alpha muteins and a process for preparing them
CZ302862B6 (cs) * 1998-08-14 2011-12-21 Lécivo na lécení otoku
CA2575513C (en) * 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
AT506150B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Zyklisches und cystein-freies peptid
EP2403490B1 (en) * 2009-03-04 2019-08-07 MannKind Corporation An improved dry powder drug delivery system
AT507953B1 (de) * 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
AT509267A1 (de) * 2010-01-14 2011-07-15 Apeptico Forschung & Entwicklung Gmbh Organische verbindungen zur regulierung von vektoriellen ionenkanälen
AT510585B1 (de) * 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
High altitude-induced pulmonary oedema;Marco Maggiorini;《Cardiovasc Res》;20061001;第72卷(第1期);第41-50页 *

Also Published As

Publication number Publication date
AU2013283563A1 (en) 2015-01-15
CN104427993A (zh) 2015-03-18
EA201500061A1 (ru) 2015-06-30
KR102010793B1 (ko) 2019-08-14
US20150225460A1 (en) 2015-08-13
EP2866824A1 (de) 2015-05-06
IN2015DN00585A (OSRAM) 2015-06-26
US9802985B2 (en) 2017-10-31
MX2014015048A (es) 2015-06-05
AP2014008162A0 (en) 2014-12-31
EA030384B1 (ru) 2018-07-31
PE20150198A1 (es) 2015-02-19
US20190211061A1 (en) 2019-07-11
ES2602197T3 (es) 2017-02-20
WO2014001177A1 (de) 2014-01-03
CA2875749C (en) 2019-02-26
EP2866824B1 (de) 2016-08-10
JP6113277B2 (ja) 2017-04-12
KR20150037815A (ko) 2015-04-08
EP2679239A1 (de) 2014-01-01
CA2875749A1 (en) 2014-01-03
JP2015526399A (ja) 2015-09-10
AU2013283563B2 (en) 2017-06-08
MX354302B (es) 2018-02-23

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