CN104383232A - Broadleaf holly leaf lozenge with effects of clearing away heat and toxic materials and production method thereof - Google Patents
Broadleaf holly leaf lozenge with effects of clearing away heat and toxic materials and production method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a broadleaf holly leaf lozenge with effects of clearing away heat and toxic materials and a production method thereof. The broadleaf holly leaf lozenge is characterized by being prepared from the following raw materials in parts by weight: 90-100 parts of broadleaf holly leaf, 20-30 parts of dittany bark, 8-12 parts of radices stellariae dichotomae, 4-8 parts of thunberg fritillary bulb, 4-8 parts of pomegranate bark, 3-5 parts of codonopsis lanceolata, 1-2 parts of wild buckwheat, 1-2 parts of Indian strawberry, 1-2 parts of humifuse euphorbia herb, 1-2 parts of rhizoma picrorhizae, 1-2 parts of menthol, 1-2 parts of monocrystal rock sugar, 50-70 parts of filling agent and 10-15 parts of lubricating agent. The broadleaf holly leaf lozenge with effects of clearing away heat and toxic materials disclosed by the invention is fast in curative effect, does not have any toxic or side effect and has the characteristics of effects of clearing away heat and toxic materials, relieving swelling and pain, relieving sore-throat and moistening the throat, dissolving phlegm and quenching thirst and improving the human immunity.
Description
Technical field
The invention belongs to Chinese herbal medicine preparation technology field, be specifically related to a kind of heat-clearing and toxic substances removing buccal lozenge of lectuce tea and production method thereof.
Background technology
Along with the progress of society, the job and life stress of people is increasing, easily occurs containing in fire-toxin, attacks the symptom such as caused pharyngitis, red swelling of gingiva pain, constipation, heating, thirsty, abdominal distention, red tongue on burning hot; Some people is because easily there is the symptom of catching a cold, having a fever in the reason of health.The traditional Chinese medical science think heat syndrome be human feeling sun heat heresy, as ailment said due to cold or exposure, pathogenic heat, pathogenic fire etc., or overabundance of YANG leading to deficiency of YIN, the high Sheng of internal organs yang-energy and consumption of YIN-fluid, hyperfunction the showed syndrome of functional activity.Many tumors and many obstinate dermatopathies are all the performances of very typical heat syndrome clinically.
At present, the medicine of market being treated heat-clearing and toxic substances removing is also more, comprises Western medicine and treatment by Chinese herbs, and general treatment is based on Western medicine, and curative effect is obvious, but has side effect once.The Chinese medicine kind of heat-clearing and toxic substances removing common is in the market a lot, but ubiquity has therapeutic effect not obvious, and onset is slow especially, and some medicine also has untoward reaction, and after taking medicine, patient cannot be engaged in normal work, have impact on the life of patient, work.Chinese medicine food materials have superiority in problem at solution heat-clearing and toxic substances removing, if on the basis of theory of Chinese medical science, give full play to the advantage of Chinese medicine, develop the product of better efficacy, the Social and economic benef@that can obtain.Such as Traditional Chinese medicine lozenge directly can act on affected part the long time, has become the favorite product type of pyretic toxicity Disease of dysphagia.Existing many heat-clearing and toxic substances removing buccal tablets in the market, the certain therapeutic effect of they each tools, to some extent solves the needs of people to treatment heat-clearing and toxic substances removing.
Modern medicine study shows, containing 200 Multiple components such as Herba Lactucae formosanae Saponin, aminoacid, vitamin C, Polyphenols, flavonoid, caffeine, protein in Folium Ilicis, there is clearing away heat and removing summer, eyesight-improving intelligence-developing, promoting the production of body fluid to quench thirst, diuresis heart tonifying, the cough-relieving that wets one's whistle, blood fat reducing, blood pressure lowering, blood sugar lowering, fat-reducing, press down cancer anti-cancer, defying age, the multiple efficacies such as arteries and veins of invigorating blood circulation.It is one of study hotspot of tea health-care food, the edible way of Folium Camelliae sinensis is main mainly with bubble drink for a long time, and form is comparatively single, and utilization rate is not high enough, to steep with traditional bag or compared with the bubble that falls apart, Folium Camelliae sinensis buccal tablet is easy to carry, uses simple, can utilize its effective ingredient to greatest extent, meet modern's nourishing healthy, simple and efficient consumption demand, but due to problems such as tea flavour are too light, mouthfeel is not good, cause the degree of recognition in market not high, cannot meet the need of market.Therefore, develop a kind of heat-clearing and toxic substances removing buccal lozenge of lectuce tea to be very important.
Summary of the invention
The object of the invention is not enough for above-mentioned prior art and provide a kind of curative effect fast, have no side effect; There is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, sore-throat relieving wets one's whistle, expectorant is quenched the thirst, improve effect buccal lozenge of lectuce tea of body immunity and production method thereof.
The present invention realizes by the following technical solutions:
Heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention, be made up of the raw material of following parts by weight:
Folium Ilicis 90-100 part, Cortex Dictamni 20-30 part, Radix Stellariae 8-12 part, Bulbus Fritillariae Thunbergii 4-8 part, Pericarpium Granati 4-8 part, wheel blade Radix Codonopsis 3-5 part, Rhizoma Fagopyri Dibotryis 1-2 part, Herba Duchesneae Indicae 1-2 part, Herba Euphorbiae Humifusae 1-2 part, Rhizoma Picrorhizae 1-2 part, Mentholum 1-2 part, monocrystal rock sugar 1-2 part, filler 50-70 part, lubricant 10-15 part.
Above-described heat-clearing and toxic substances removing buccal lozenge of lectuce tea, is made up of the raw material of following parts by weight: Folium Ilicis 95 parts, Cortex Dictamni 25 parts, Radix Stellariae 10 parts, Bulbus Fritillariae Thunbergii 6 parts, Pericarpium Granati 6 parts, wheel blade Radix Codonopsis 4 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Duchesneae Indicae 1 part, Herba Euphorbiae Humifusae 1 part, Rhizoma Picrorhizae 1 part, Mentholum 1 part, monocrystal rock sugar 1 part, filler 60 parts, lubricant 12 parts.
The present invention is made up of Chinese medicinal materials such as Folium Ilicis, Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae, and curative effect is fast, have no side effect; There is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, sore-throat relieving wets one's whistle, expectorant is quenched the thirst, improve effect of body immunity.
Each medicine active ingredient of above-described heat-clearing and toxic substances removing buccal lozenge of lectuce tea Chinese medicine formula is analyzed:
Folium Ilicis, [another name] Cortex Ilicis Rotundae; [Latin] Ilex latifolia Thunb, Cucurbitaceae is the leaf of holly plant Cortex Ilicis Rotundae (formal name used at school: Folium llicis Latifoliae), in being born in hillside, bamboo grove, bushes.Be distributed in THE LOWER YANGTZE VALLEY each province and Fujian.Folium Ilicis is commonly called as tea fourth, Fu Dingcha, highland Lu's tea, is a kind of traditional pure natural health-care beverage good merchantable brand of China, have the laudatory title such as " health tea ", " cosmetic tea ", " diet tea ", " blood-pressure decreasing tea ", " lengthen one's life tea ".[nature and flavor] are sweet, bitter, cold; [function cures mainly] has clearing away heat and removing summer, eyesight-improving intelligence-developing, promoting the production of body fluid to quench thirst, diuresis heart tonifying, the cough-relieving that wets one's whistle, blood fat reducing, blood pressure lowering, blood sugar lowering, fat-reducing, presses down cancer anti-cancer, defying age, the multiple efficacies such as arteries and veins of invigorating blood circulation.1. Compendium of Material Medica: Folium Ilicis has loose wind heat, refresh oneself, promoting the production of body fluid to quench thirst, help digestion refresh oneself, the pharmacological function such as eliminating inflammation and expelling toxin, hypertension and hyperlipemia.2. " book on Chinese herbal medicine is new again ": eliminate indigestion and phlegm, relieving restlessness is quenched the thirst, profit two just, is deoiled greasy.3. " Traditional Chinese Medicine in Sichuan will ": energy clearing away heat to dispel wind, relieving restlessness is quenched one's thirst.Control headache, toothache, tinnitus, conjunctival congestion and dyspepsia and have expectorant.
Cortex Dictamni, [another name] northern Cortex Dictamni, moss skin, pericarpium Zanthoxyli root bark, smelly root bark, [Latin] CORTEX DICTAMNI is Rosaceae gul, distribution Liaoning, Hebei, Shandong, Jiangsu, Shanxi, the Inner Mongol, Jilin, Heilungkiang.[nature and flavor] are bitter, salty, cold, [function cures mainly] heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances; Cure mainly: the rubella caused by wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia.1. " Bencao Jingshu ": Cortex Dictamni, hardship can expel the heat-evil, cold energy heat extraction, therefore main wind syndrome of head has fire syndrome.2. " book on Chinese herbal medicine is original ": Cortex Dictamni, enters lung meridian, therefore can remove wind, enters small intestine meridian, therefore can dry, and husband's rheumatism was both removed, then vim and vigour from living, also go by heat.3. " property of medicine opinion ": control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red rotten, and eyebrow loss of hairs is crisp, musculus cutaneus is anxious, high fever aversion to cold; Principal solution heat is yellow, wine is yellow, acute jaundice, paddy Huang, labor are yellow.
Radix Stellariae, [another name] Yin Hu, mountain dish root, mountain horse steps on dish root, Gaster Bovis seu Bubali root, Radix Adenophorae (Radix Glehniae), Bletilla striata (Thunb.ex A.Murray)Rchb.f., soil ginseng; [Latin] RadixStellariae is the dry root of pinkwort Radix Stellariae Stellaria dichotoma L.var.lanceolata Bge; Be distributed in the ground such as the northwestward of China, the Inner Mongol; [nature and flavor] sweetness and bitterness, cool; [function cures mainly] has clearing heat and relieving fidgetness, effect of inducing diuresis for treating stranguria syndrome, cures mainly calentura excessive thirst, aphtha of the mouth and tongue, gingival swelling and pain, cough due to lung-heat, and gastric heat is vomitted the diseases such as the sound of vomiting.1. " book on Chinese herbal medicine asks former ": lung heat clearing, stomach, spleen, kidney-heat, holding concurrently can removing heat from blood.Be in harmony deficient five internal organs, skin consumptive fever, the tired pain of hectic fever due to YIN-deficiency; Arthralgia chiefly caused by damp pathogen contracture.2. " Chinese Herbal Medicine in Xinjiang handbook ": clearing away heat and cooling blood.Be in harmony pulmonary tuberculosis hectic fever.3. " herbal classic is met former ": Radix Stellariae, its nature and flavor and Herba Dendrobii are very mutually not far away.Not only heat clearing away, holding concurrently can removing heat from blood.
Bulbus Fritillariae Thunbergii, [another name] Rhizoma Bolbostematis, Bulbus Fritillariae Thunbergii, resembles shellfish, Bulbus Fritillariae Thunbergii, Bulbus Fritillariae Thunbergii; [Latin] Fritillaria thunbergii Miq.; Perennial herb, distribution Jiangsu (south), Zhejiang (the north) and Hunan.[nature and flavor] are sweet light, cool.[function cures mainly] removing heat-phlegm, powder detoxifcation.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.1. detailed outline is picked up any lost article from the road ": detoxify sharp expectorant, opens lung qi dispersing gas, and all lung men folder wind-fire has expectorant, and person should this.2. " Shandong Chinese herbal medicine handbook ": " removing heat from the lung and dissipating phlegm, antacid, removing toxic substances.Cure cold cough, and stomachache acid regurgitation, carbuncle poison swells and ache.3. " Bencao Congxin ": when going, feel wind-phlegm.
Pericarpium Granati, [another name] Punica granatum L. shell, Fructus punicae granati skin, sour pomegranate skin; [Latin] Pomegranate Rind. is the peel of Punicaceae plant Punica granatum L., and China's most area all has distribution.Flavor efficacy: sour and astringent, warm.[function cures mainly] astringing intestine to stop diarrhea, hemostasis, anthelmintic.Control chronic diarrhea, chronic dysentery, have blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.1. " detailed outline ": antidiarrheal dysentery, hematochezia, proctoptosis, metrorrhagia leukorrhagia.2. " not Lu ": treat dysentery, leak-stopping essence.3. " the SHENGCAO property of medicine is standby to be wanted ": control tumor skin ulcer, wash colic.
Wheel blade Radix Codonopsis, [another name] lance asiabell root, milk ginseng, Lac caprae seu ovis, Radix Codonopsis Lanceolatae; [Latin] Codonopsis lanceolatae (Sieb. et Zucc.) Trauv, a kind of perennial draft of overgrowing; Be distributed in the ground such as northeast and Hebei, Shanxi, Shandong, Henan, Anhui, Jiangxi, Hubei, Jiangsu, Zhejiang, Fujian, Guangxi.[nature and flavor] are sweet, Xin Ping, and [function cures mainly] relieves internal heat anticancer, benefiting qi and nourishing blood, detumescence and apocenosis.Control lung abscess, acute mastitis, acute appendicitis, toxic swelling, scrofula, throat moth, breast is few, leucorrhea.1. Guangzhou army " conventional Chinese herbal medicine handbook ": strengthening by means of tonics, lung moistening of eliminating the phlegm, promoting pus discharge and removing toxic substances.Control pulmonary abscess, mastitis, carbuncle pyogenic infections from tumour or sore, venom.。2. " detailed outline is picked up any lost article from the road ": control toxic swelling scrofula, extracting juice and wine clothes, slag applies affected part.3. " not Lu ": main dizziness pain, QI invigorating, longue meat.
Rhizoma Fagopyri Dibotryis, [another name] Radix Et Rhizoma Fagopyri Tatarici, wild bridge Semen Fagopyri Esculenti, sky Semen Fagopyri Esculenti; [Latin] Fagopyrum dibotrys (D. Don) Hara is polygonaceae plant Rhizoma Fagopyri Dibotryis Fagopyrum dibotrys(D.Don) dry rhizome of Hara; Be distributed in the ground such as Shaanxi, Henan, Jiangsu, Zhejiang, Jiangxi, Hubei, Guangdong, Guangxi, Guizhou, Yunnan, Sichuan.[nature and flavor] are micro-pungent, puckery, cool, [function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle of invigorating blood circulation, expelling wind and removing dampness sore, snake bite and insect sting; Cure mainly the diseases such as lung abscess, lung-heat cough with asthma, laryngopharynx swelling and pain, dysentery, rheumatism arthromyodynia, traumatic injury, carbuncle cancer.1. supplementary Amplifications of the Compendium of Materia Medica: control inflammation of the throat, acute throat trouble larynx poison, gargles larynx with vinegar mill.Control nebulousurine, smash juice and rush wine clothes.2. supplement to the Herbal: main carbuncle malignant boil poison is swollen, red white trip rash, and worm, silkworm, Serpentis, dog sting, and vinegar rubs in deposited skin ulcer, also smash stem and leaf and apply it; Probably poison enters abdomen, and liquor is drunk.
Herba Duchesneae Indicae, [another name] cockscomb fruit, wild Fructus Myricae rubrae, Serpentis Fischer, the certain kind of berries, the silkworm certain kind of berries, Laticauda semifasciata, three-jaw phoenix, Clerodendrum thomsonae Balf.; [Latin] Duchesnea indica (Andr.) Focke is the plant that Rosaceae Herba Duchesneae Indicae belongs to, perennial grass of crawling; Be distributed in each provinces and regions on the south Liaoning.[nature and flavor] sweetness and bitterness, cold, [function cures mainly] heat clearing away, removing heat from blood, detumescence, removing toxic substances.Control calentura, infantile convulsion, cough, spit blood, laryngopharynx swelling and pain, dysentery, carbuncle, furuncle, snake bite and insect sting, burn.1. " east, Fujian book on Chinese herbal medicine ": preventing phlegm from forming and stopping coughing, dispel the wind, invigorate blood circulation.Control Common Cold, cough, asthma, acute toothache, aphtha of the mouth and tongue.2. " Traditional Chinese Medicine in Sichuan will ": removing heat from blood, stimulate the menstrual flow.Control infantile convulsion cold and heat, treat laryngopharynx swelling and pain.3. " not Lu ": main enlargement or puffiness of the chest and abdomen heat is more than.
Herba Euphorbiae Humifusae, [another name] Herba Chenopodii Hybridi, milk grass, Hong Liancao, iron wire Herba Portulacae, little red muscle grass, Alternanthera sessilis (L.) DC., blood are through base; [Latin] Euphorbia humifusa Willd, the annual draft of crawling of Euphorbia maculata L.; All there is distribution all parts of the country.[nature and flavor] are pungent, flat, and [function cures mainly] heat-clearing and toxic substances removing, invigorates blood circulation, hemostasis, dampness removing, lactogenesis.Control bacillary dysentery, enteritis, hemoptysis, spit blood, have blood in stool, metrorrhagia, traumatic hemorrhage, jaundice due to damp-heat, galactostasis, carbuncle furuncle, treating swelling and pain by traumatic injury.1. " Fujian Chinese herbal medicine ": " clearing away heat and cooling blood, subduing swelling and detoxicating.2. " praise and help book on Chinese herbal medicine ": " main through-flow blood vessels, also can with controlling gas.3. " Chinese herbal medicine is commonly used in Shanghai ": " hemostasis, diuresis, stomach invigorating, promoting blood circulation and detoxication.
Rhizoma Picrorhizae, [another name] cuts lonely dew pool, Rhizoma Picrorhizae, Rhizoma Picrorhizae; [Latin] Picrorhiza scrophulariiflora Pennell. is Scrophulariaceae herbaceos perennial; Be distributed in Sichuan, Yunnan, Tibet, Himalayas.[nature and flavor] are bitter, cold, [function cures mainly] heat clearing away, removing heat from blood, dampness.Control infantile malnutrition, infantile convulsion, dysentery, consumptive fever hectic fever due to YIN-deficiency, spontaneous perspiration, night sweat, spit blood, epistaxis, acute catarrhal conjunctivitis, hemorrhoid complicated by anal fistula, skin infection.Tang Materia Medica: main bone swallow consumptive fever, tonifying liver gallbladder, improving eyesight.Control and cold and hotly let out dysentery, beneficial color, thick the intestines and stomach, control married woman's tire and steam false alarm, three disappear five hemorrhoid, adult's dysphoria with feverish sensation in the chest palms and soles; Very good with human milk leaching point order.2. " Kaibao Bencao ": main chronic dysentery becomes infantile malnutrition, typhoid cough, pyrexial malaria, bone heat, reason waist kidney, removes polyhidrosis around the external genitals, pediatric epilepsy scared, cold and heat, not lower food, cholera dysentery.
Mentholum is a kind of chemical agent, is extracted by the leaf of Herba Menthae and stem, white crystal, molecular formula C
10h
20o is the main component in Herba Menthae and lavender quintessence oil.Being pharmaceutically used as excitants, acting on skin or mucosa, having refrigerant itching-relieving action; Take orally and can be used as carminative, for headache and nose; Pharynx; Laryngitis etc.Its ester is used for spice and medicine.
Monocrystal rock sugar dissolves post crystallization by white sugar purification to form, in monocrystalline shape.[nature and flavor] are sweet; Flat [return through] spleen; Lung meridian [function cures mainly] invigorating the spleen and regulating the stomach; Nourishing the lung to arrest cough.Main deficiency of spleen-QI and stomach-QI; Xeropulmonary cough; Or sputum mixed with blood.
The preparation method of heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention made by above-mentioned each component medicine, comprises the following steps:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by.
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
Above-described alcohol settling is that the ethanol of 80-90% adds in concentrated solution by mass fraction, slowly adds while stirring, and when being adjusted to that in concentrated solution, alcohol content is 40-70%, airtight 2-4 hour refilters.
Above-described filler is starch, dextrin, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, mannose, xylitol, one or more in carboxymethyl starch sodium.
Above-described wet and slippery dose is one or more in stearate, Pulvis Talci, hydride vegetable oil, Polyethylene Glycol.
Heat-clearing and toxic substances removing fourth tea buccal tablet of the present invention, according to the condition of different situations and processing factory, can also make Folium Ilicis liquid beverage, Herba Lactucae formosanae teabag, Folium Ilicis dissolved granule and other goods.
The invention has the beneficial effects as follows:
1, heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention adopts and originates from that the herbaceous plant such as Daxin County, Guangxi Folium Ilicis are refining to be formed, Folium Ilicis, Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae are all the raw materials of medicine-food two-purpose, have no side effect, without bad smell, mouthfeel is pure and fresh, natural, tasty and refreshing.
2, heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention have curative effect fast, have no side effect; There is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, sore-throat relieving wets one's whistle, expectorant is quenched the thirst, improve effect of body immunity.
3, heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention adds monocrystal rock sugar and Mentholum, makes buccal lozenge of lectuce tea mouthfeel micro-sweet, salubrious, eliminates the bitterness of Folium Ilicis, and liking more by people, suitable any crowd takes.
4, the present invention is according to modern Chinese medicine pharmacology, and material composition and weight portion are through long-term test and repeatedly compare and use, and have drawn scientific compatibility, is use, interwoveness mutually, has good therapeutic effect.
5, heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention have passed through clinical trial for many years, constantly gropes the Traditional Chinese medicine lozenge of a kind of heat-clearing and toxic substances removing formed.Can reach more than 100% through clinical treatment effective percentage, cure rate reaches more than 95%, and drug effect is remarkable.
detailed description of the invention
Embodiment 1:
(1) raw material and weight:
Folium Ilicis 90 parts, Cortex Dictamni 20 parts, Radix Stellariae 8 parts, Bulbus Fritillariae Thunbergii 4 parts, Pericarpium Granati 4 parts, wheel blade Radix Codonopsis 3 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Duchesneae Indicae 1 part, Herba Euphorbiae Humifusae 1 part, Rhizoma Picrorhizae 1 part, Mentholum 1 part, monocrystal rock sugar 1 part, filler 50 parts, lubricant 10 parts.
(2) production method:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by.
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
Described filler is xylitol; Described wet and slippery dose is Pulvis Talci.
Embodiment 2:
(1) raw material and weight:
Folium Ilicis 95 parts, Cortex Dictamni 25 parts, Radix Stellariae 10 parts, Bulbus Fritillariae Thunbergii 6 parts, Pericarpium Granati 6 parts, wheel blade Radix Codonopsis 4 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Duchesneae Indicae 1 part, Herba Euphorbiae Humifusae 1 part, Rhizoma Picrorhizae 1 part, Mentholum 1 part, monocrystal rock sugar 1 part, filler 60 parts, lubricant 12 parts.
(2) production method:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by.
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
Described filler is starch; Described wet and slippery dose is stearate.
Embodiment 3:
(1) raw material and weight:
Folium Ilicis 98 parts, Cortex Dictamni 28 parts, Radix Stellariae 11 parts, Bulbus Fritillariae Thunbergii 7 parts, Pericarpium Granati 7 parts, wheel blade Radix Codonopsis 4 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Duchesneae Indicae 2 parts, Herba Euphorbiae Humifusae 2 parts, Rhizoma Picrorhizae 2 parts, Mentholum 2 parts, monocrystal rock sugar 2 parts, filler 65 parts, lubricant 14 parts.
(2) production method:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by.
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
Described filler is lactose; Described wet and slippery dose is hydride vegetable oil.
Embodiment 4:
(1) raw material and weight:
Folium Ilicis 100 parts, Cortex Dictamni 30 parts, Radix Stellariae 12 parts, Bulbus Fritillariae Thunbergii 8 parts, Pericarpium Granati 8 parts, wheel blade Radix Codonopsis 5 parts, Rhizoma Fagopyri Dibotryis 2 parts, Herba Duchesneae Indicae 2 parts, Herba Euphorbiae Humifusae 2 parts, Rhizoma Picrorhizae 2 parts, Mentholum 2 parts, monocrystal rock sugar 2 parts, filler 70 parts, lubricant 15 parts.
(2) production method:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by.
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
Described filler is starch, dextrin, microcrystalline Cellulose and mannose; Described wet and slippery dose is stearate and stone powder.
application Example
Heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention studied in 2013 and the product manufacturing experimently out is taken to part population, and volunteer 30, wherein has the symptoms such as xerostomia, constipation, yellowish urine, bronchitis, pharyngolaryngitis, oral ulcer, flu, fever.Take 4-8 sheet every day, result patient takes rear effective percentage and reaches 100%, and cure rate reaches more than 95%.
Model case
1, Luo, female, 45 years old, initiation bronchitis of getting angry, cough through taking heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention, took 4-8 sheet every day in 3 days incessantly, and within 3 days, cough symptom greatly alleviates, and after taking a week, cough symptom is fully recovered.
2, Lee so-and-so, man, 38 years old, suffer from influenza, sensation headache, rhinorrhea, through taking heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention, take 4-8 sheet every day, after 1 day, headache disappear, stop rhinorrhea, continue to take the present invention after 2 days, throw off a cold.
3, Tan, man, 32 years old, smoking insobriety, caused oral ulcer, take plurality of Chinese, DeGrain, take heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention upon somebody's introduction, take 4-8 sheet every day, after 1 day, throat inflammation, cough symptom greatly alleviate, and continue to take 3 days, oral ulcer is fully recovered.
4, Wu so-and-so, female, 40 years old, xerostomia, constipation, yellowish urine, through taking heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention, take 4-8 sheet every day, after the course for the treatment of, symptom alleviated, and continues to take condition after a course for the treatment of.
5, Wei, 5 years old, because of the inflammation of flu tonsil, fever, through taking heat-clearing and toxic substances removing buccal lozenge of lectuce tea of the present invention, taking 4-8 sheet every day, bringing down a fever after taking 1 day, continue to take, need not eat other Chinese medicine and western medicine after 5 days, tonsil inflammation was fully recovered, and body temperature is normal.
Claims (6)
1. a heat-clearing and toxic substances removing buccal lozenge of lectuce tea, is characterized in that: be made up of the raw material of following parts by weight: Folium Ilicis 90-100 part, Cortex Dictamni 20-30 part, Radix Stellariae 8-12 part, Bulbus Fritillariae Thunbergii 4-8 part, Pericarpium Granati 4-8 part, wheel blade Radix Codonopsis 3-5 part, Rhizoma Fagopyri Dibotryis 1-2 part, Herba Duchesneae Indicae 1-2 part, Herba Euphorbiae Humifusae 1-2 part, Rhizoma Picrorhizae 1-2 part, Mentholum 1-2 part, monocrystal rock sugar 1-2 part, filler 50-70 part, lubricant 10-15 part.
2. heat-clearing and toxic substances removing buccal lozenge of lectuce tea according to claim 1, is characterized in that: be made up of the raw material of following parts by weight: Folium Ilicis 95 parts, Cortex Dictamni 25 parts, Radix Stellariae 10 parts, Bulbus Fritillariae Thunbergii 6 parts, Pericarpium Granati 6 parts, wheel blade Radix Codonopsis 4 parts, Rhizoma Fagopyri Dibotryis 1 part, Herba Duchesneae Indicae 1 part, Herba Euphorbiae Humifusae 1 part, Rhizoma Picrorhizae 1 part, Mentholum 1 part, monocrystal rock sugar 1 part, filler 60 parts, lubricant 12 parts.
3. the production method of a heat-clearing and toxic substances removing buccal lozenge of lectuce tea, it is characterized in that: the extraction comprising the extraction of Folium Ilicis effective ingredient and Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae effective ingredient, concrete steps are as follows:
(1) pour extraction pot into after being pulverized by Folium Ilicis by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution A;
(2) medicinal residues after filtration in step 1 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution B;
(3) medicinal residues after filtration in step 2 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, extracting solution A and extracting solution B is mixed stirring, the ethanol adding extracting solution weight 5 times precipitates again, and filters after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(4) Cortex Dictamni, Radix Stellariae, Bulbus Fritillariae Thunbergii, Pericarpium Granati, wheel blade Radix Codonopsis, Rhizoma Fagopyri Dibotryis, Herba Duchesneae Indicae, Herba Euphorbiae Humifusae, Rhizoma Picrorhizae is poured into extraction pot after pulverizing by weight, add 10 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusion 1.5-2 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution C;
(5) medicinal residues after filtration in step 4 are added 5 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 1 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, obtain extracting solution D;
(6) medicinal residues after filtration in step 5 are added 3 times that the water yield is medicine gross weight, be heated to 100 DEG C of infusions 0.5 hour, when fluid temperature is down to 35-50 DEG C, filter through 120 eye mesh screens, then extracting solution C and extracting solution D to be mixed, first add Mentholum and monocrystal rock sugar stirs, the ethanol adding extracting solution weight 5 times again precipitates, filter after alcohol settling 2-4 hour, vacuum concentration is the concentrated solution of 1.3 to proportion, preserves stand-by;
(7) concentrated solution of the concentrated solution of 60-70% step 3 and 30-40% step 6 is poured in material-compound tank mix, stir after adding filler and wet and slippery dose, be condensed into thick paste and make soft material; Soft material is crossed 18 eye mesh screens and carry out pelletize, then dry at 50-60 DEG C, gained granule carries out tabletting, obtains heat-clearing and toxic substances removing buccal lozenge of lectuce tea.
4. the production method of heat-clearing and toxic substances removing buccal lozenge of lectuce tea according to claim 3, it is characterized in that: described alcohol settling is that the ethanol of 80-90% adds in concentrated solution by mass fraction, slowly add while stirring, when being adjusted to that in concentrated solution, alcohol content is 40-70%, airtight 2-4 hour refilters.
5. the production method of heat-clearing and toxic substances removing buccal lozenge of lectuce tea according to claim 3, it is characterized in that: described filler is starch, dextrin, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, mannose, xylitol, one or more in carboxymethyl starch sodium.
6. the production method of heat-clearing and toxic substances removing buccal lozenge of lectuce tea according to claim 3, is characterized in that: described wet and slippery dose is one or more in stearate, Pulvis Talci, hydride vegetable oil, Polyethylene Glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105076602A (en) * | 2015-07-17 | 2015-11-25 | 冯爱丽 | Herbal tea containing duchesnea indica and preparation method thereof |
| CN109007152A (en) * | 2018-07-25 | 2018-12-18 | 兴义市绿缘中药材种植农民专业合作社 | A kind of processing method of leaflet Kuding tea bag |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1302655A (en) * | 2000-12-29 | 2001-07-11 | 广西大学 | Compound buccal lozenge of lectuce tea and its preparing process |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1302655A (en) * | 2000-12-29 | 2001-07-11 | 广西大学 | Compound buccal lozenge of lectuce tea and its preparing process |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105076602A (en) * | 2015-07-17 | 2015-11-25 | 冯爱丽 | Herbal tea containing duchesnea indica and preparation method thereof |
| CN109007152A (en) * | 2018-07-25 | 2018-12-18 | 兴义市绿缘中药材种植农民专业合作社 | A kind of processing method of leaflet Kuding tea bag |
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| CN104383232B (en) | 2018-06-05 |
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