CN105878796A - Vinegar beverage capable of treating type-II diabetes mellitus complicated with dyslipidemia and preparation method of vinegar beverage - Google Patents
Vinegar beverage capable of treating type-II diabetes mellitus complicated with dyslipidemia and preparation method of vinegar beverage Download PDFInfo
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Abstract
The invention discloses a vinegar beverage capable of treating type-II diabetes mellitus complicated with dyslipidemia. The vinegar beverage is prepared from the following main medicinal materials in parts by weight: 2-6 parts of licorice root, 2-6 parts of sea buckthorn fruits, 6-10 parts of rhizoma ligustici wallichii, 4-8 parts of honeysuckle flowers, 5-10 parts of herba portulacae, 3-7 parts of fructus trichosanthis, 1-5 parts of the seeds of Chinese dodder, 4-8 parts of radix salviae miltiorrhizae, 7-12 parts of rhizoma coptidis, 3-5 parts of American ginseng, 8-14 parts of radix morindae officinalis, 5-15 parts of cortex lycii radicis, 6-12 parts of lalang grass rhizome, 10-20 parts of bitter gourd, and 30-60 parts of rice vinegar. The vinegar beverage has the efficacies of regulating the blood sugar and controlling the dyslipidemia, the medicinal materials are easily available, and are low in cost and mild in property, and therefore, no financial burden or physical burden is caused to a user after long-term use of the vinegar beverage.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of vinegar beverage treating type ii diabetes merging dyslipidemia and preparation method thereof.
Background technology
Type 2 diabetes mellitus original name, Adult Onset's patients with type Ⅰ DM, how 35～the sequela of 40 years old, accounts for diabetics more than 90%.Type 2 diabetes mellitus produces the ability of insulin in the patient and not completely loses, the insulin in the patient having even produces too much, but the action effect of insulin is poor, insulin the most in the patient is a kind of shortage relatively, can be stimulated the secretion of internal insulin by some oral drugs.But some client need use of exogenous insulins are still had to the later stage.
The cause of disease 1. inherited genetic factors: as type 1 diabetes, type 2 diabetes mellitus has more significantly family history.The gene that some of which is caused a disease is determined, and some is still in conceptual phase.2. environmental factors: epidemiological study shows, obesity, high caloric diet, physical exertion is not enough and increases age is the topmost environmental factors of type 2 diabetes mellitus, and the factor such as dyslipidemia, dyslipidemia also can increase risk.3. age factor: most of type 2 diabetes mellitus in 30 years old with sequela.In the type 2 diabetes mellitus patient that half newly diagnoses, during morbidity, the age is more than 55 years old.4. ethnic factor: compare with white people and Aisan, type 2 diabetes mellitus is easier in native American people, Africa--American and Spain crowd occurs.5. life style: take in high heat and unreasonable structure (higher fatty acid, high protein, low-carb) meals can be causeed fat, increase and shortage sports along with body weight, insulin resistant can increase the weight of by Progressive symmetric erythrokeratodermia, and then causes the generation of defect of insulin secretion and type 2 diabetes mellitus.The main inducing causing type 2 diabetes mellitus includes that obesity, physical exertion are very few and stress.Stress include anxiety, fatigue, direct stimulation, wound, perform the operation, give a birth, other major diseases, and use hormone rising hyperglycemia etc..Due to above-mentioned inducement, the sensitivity of insulin is gradually lowered by insulin secreting ability and the health of patient, and blood glucose raises, and causes diabetes.
Clinical manifestation: in type 2 diabetes mellitus, a part of patient is based on insulin resistant, and how fat patient is, because of insulin resistant, insulin sensitivity declines, in blood, insulin increases to compensate its insulin resistant, but for the hyperglycemia of relative patient, insulin secretion still relative deficiency.This type of patient's early symptom is inconspicuous, only has the most weak, thirsty, big blood vessel and microvascular complication often just can occur before clarifying a diagnosis.Diet Therapy and oral antidiabetic drug is many can be effective.Another part patient, based on defect of insulin secretion, requires supplementation with exogenous insulin clinically.Type 2 diabetes mellitus: be common in middle-aged and elderly people, overweight people's sickness rate is high, often can be with dyslipidemia, the disease such as dyslipidemia, arteriosclerosis.Insidious onset, in early days without any symptom, or only has the most weak, the most thirsty, and blood glucose increases inconspicuous person need to be done carbohydrate tolerance test and just can make a definite diagnosis.Serum insulin levels is the most normal or increases, and late period is low.
In existing treatment type ii diabetes merges the technology of dyslipidemia, the patent of Authorization Notice No. CN 103110815 B (application number 201310038151.1) discloses the preparation method of a kind of Chinese medicine composition treating type ii diabetes, it is characterized in that, take off the crude drug stating weight proportion: Radix Astragali 10-30 part, Radix Panacis Quinquefolii 9-30 part, Radix Rehmanniae 12-30 part, Rhizoma Dioscoreae 15-30 part, Rhizoma Polygonati Odorati 6-12 part, Fructus Lycii 5-15 part, Radix Asparagi 10-20 part, Radix Scrophulariae 10-15 part, Fructus Ligustri Lucidi 6-15 part, Radix Puerariae 7-15 part, Fructus Momordicae charantiae powder 20-50 part, Radix Linderae 3-9 part, Fructus Mori 9-15 part, Radix Astragali 15-30 part；Preparation process is as follows: 1. put in marmite the Radix Astragali, Radix Panacis Quinquefolii, Radix Rehmanniae, Rhizoma Dioscoreae, Rhizoma Polygonati Odorati, Fructus Lycii, Radix Asparagi, Radix Scrophulariae, Fructus Ligustri Lucidi, Radix Puerariae, the Radix Linderae, Fructus Mori, the Radix Astragali by cold water soak 20-40 minute；2. the medical material big fire soaked is fried open, turns little fire and decoct 25-35 minute, leach medicinal liquid；3. after leaching medicinal liquid, again add cold water and be fried open, turn little fire and decoct 20-40 minute, close fire and add Fructus Momordicae charantiae powder in previous minute, leach medicinal liquid, mix with 2. herb liquid, be divided into two parts.Although achieving good curative effect in terms for the treatment of type ii diabetes, but its purpose that cannot accomplish type ii diabetes carries out Coryza Treated by Syndrome Differentiation, and processing refinement operation trouble, relatively costly.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind for the treatment of type ii diabetes to merge the vinegar beverage of dyslipidemia, there is regulation blood glucose, effect of control dyslipidemia, crude drug source of the present invention is easy to get, with low cost, selected raw material mostly is the thing of mild in medicine property sum, and life-time service also will not increase the burden in economy and health to user.
Another object of the present invention is just to provide the preparation method that above-mentioned treatment type ii diabetes merges the vinegar beverage of dyslipidemia.
The technical scheme is that
A kind of type ii diabetes for the treatment of merges the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from: Radix Glycyrrhizae 2-6 part, Fructus Hippophae 2-6 part, Rhizoma Chuanxiong 6-10 part, Flos Lonicerae 4-8 part, Herba portulacae 5-10 part, Fructus Trichosanthis 3-7 part, Semen Cuscutae 1-5 part, Radix Salviae Miltiorrhizae 4-8 part, Rhizoma Coptidis 7-12 part, Radix Panacis Quinquefolii 3-5 part, Radix Morindae Officinalis 8-14 part, Cortex Lycii 5-15 part, Rhizoma Imperatae 6-12 part, Fructus Momordicae charantiae 10-20 part, rice vinegar 30-60 part.
A kind of type ii diabetes for the treatment of merges the vinegar beverage of dyslipidemia, and preferred scheme is, takes off and states the primary raw material of weight proportion and be prepared from: Radix Glycyrrhizae 3-5 part, Fructus Hippophae 3-5 part, Rhizoma Chuanxiong 7-9 part, Flos Lonicerae 5-7 part, Herba portulacae 6-9 part, Fructus Trichosanthis 4-6 part, Semen Cuscutae 2-4 part, Radix Salviae Miltiorrhizae 5-7 part, Rhizoma Coptidis 9-11 part, Radix Panacis Quinquefolii 3.5-4.5 part, Radix Morindae Officinalis 10-12 part, Cortex Lycii 8-13 part, Rhizoma Imperatae 7-11 part, Fructus Momordicae charantiae 13-18 part, rice vinegar 40-50 part.
A kind of type ii diabetes for the treatment of merges the vinegar beverage of dyslipidemia, and the scheme being more highly preferred to is, takes off and states the primary raw material of weight proportion and be prepared from: 4 parts of Radix Glycyrrhizae, Fructus Hippophae 4 parts, Rhizoma Chuanxiong 8 parts, Flos Lonicerae 6 parts, Herba portulacae 7.5 parts, Fructus Trichosanthis 5 parts, Semen Cuscutae 3 parts, Radix Salviae Miltiorrhizae 6 parts, Rhizoma Coptidis 10 parts, Radix Panacis Quinquefolii 4 parts, Radix Morindae Officinalis 11 parts, Cortex Lycii 11 parts, Rhizoma Imperatae 9.5 parts, 15 parts of Fructus Momordicae charantiae, rice vinegar 45 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 80-100 degree Celsius, seal 1-5 minute, filter off filtrate, repeat the above steps 2 times, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 2-6 time, drain away the water, grind, with soaking in rice vinegar 3-8 hour, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 2-6 minute, dry in the air to crisp, grind to form smalls, cross 80-120 mesh sieve stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 20-40 minute after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 6-12 minute, it is fried open at intense fire, cross 160-200 mesh drainage screen after sealing and standing 2-6 hour, bottle and i.e. obtain vinegar beverage.
Above-mentioned preparation method, step (2) adds the hot water of 85-95 degree Celsius, seals 2-4 minute (preferably, add the hot water of 90 degrees Celsius, seal 3 minutes).
Above-mentioned preparation method, step (3) is soaked 4-7 hour with vinegar and is filtered (preferably, soak 5.5 hours with vinegar and filter).
Above-mentioned preparation method, step (3) stir-fries 3-5 minute repeatedly, dries in the air to crisp, grinds to form smalls, crosses 90-110 mesh sieve stand-by (preferably, repeatedly stir-fry 4 minutes, dry in the air to crisp, grind to form smalls, cross 100 mesh sieves stand-by).
Above-mentioned preparation method, step (4) boils in a covered pot over a slow fire 25-35 minute (preferably, boiling in a covered pot over a slow fire 30 minutes after being stirred well to melt completely) after being stirred well to melt completely.
Above-mentioned preparation method, step (5) adds the concentration (preferably, stirring while slow fire boiling adds the concentration of clear water dilute liquid medicine after 9 minutes) of clear water dilute liquid medicine after stirring slow fire boiling 8-10 minute.
Above-mentioned preparation method, crosses 170-190 mesh drainage screen (preferably, sealing and standing crosses 180 mesh drainage screens after 4 hours) after step (5) sealing and standing 3-5 hour.
Optimal using method: for making this medicine reach optimum therapeuticing effect, taking vinegar beverage 30-50ml of the present invention, the morning, noon and afternoon the most once, 5 days are a course for the treatment of every time.
The pharmacological effect of each crude drug is respectively as follows:
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, alleviate cough, eliminate the phlegm, treat pharyngalgia laryngitis；Radix Glycyrrhizae has similar adrenocortical hormone sample effect.The gastroxia causing histamine has inhibitory action；And have antiacid and alleviate gastrointestinal smooth muscle spasm effect.Licoflavone, Radix Glycyrrhizae extractum and enoxolone all have obvious antitussive effect；Phlegm-dispelling functions is the most more significant, and its action intensity is glycyrrhizic acid ＞ licoflavone ＞ Radix Glycyrrhizae extractum.Radix Glycyrrhizae also has antiinflammatory, anti-allergic effects, can protect throat and the tunica mucosa tracheae of inflammation.Radix Glycyrrhizae extractum and glycyrrhizic acid have the Detoxication of similar glucuronic acid to some poisonous substance.Radix Glycyrrhizae is commonly used to the symptom that treatment comes with climacteric. because containing glycyrrhizin in Radix Glycyrrhizae, being the compound of a kind of similar hormone, it contributes to balancing the hormone-content in women body.Subacid contained by Radix Glycyrrhizae can block the effect of Induced by Carcinogen tumor growth.Pericarpium Citri Reticulatae: nature and flavor: bitter in the mouth, pungent, warm in nature.Gui Jing: return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Fructus Hippophae: eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, fall and flutter congestive edema, blood stasis amenorrhea.Fructus Hippophae and oil have the highest medical value, it is possible to decrease cholesterol, cure the effects such as angina pectoris, also prevent and treat the effect of coronary atherosclerotic heart disease；Have and eliminate the phlegm, cough-relieving, relieving asthma and treat the effect of chronic tracheitis；Gastric duodenal ulcer and dyspepsia etc. can be treated, evident in efficacy to diseases such as chronic superficial gastritis, atrophic gastritis, colitis；To burn, scald, cutter burns, cold injury has good therapeutical effect；Cervical erosion is had good therapeutic effect.Rhizoma Chuanxiong: another name: north Cortex Dictamni, moss skin, pericarpium Zanthoxyli root bark, smelly root bark.Nature and flavor: bitter；Salty；Cold.Gui Jing: spleen channel；Lung meridian；Small intestine meridian；Stomach warp；Bladder warp.Function: heat clearing and damp drying；Dispelling wind for relieving itching；Removing toxic substances.Cure mainly: the rubella caused by wind heat noxious dampness；Eczema；Scabies；Jaundice；Damp-heat arthralgia.
Flos Lonicerae: its effect is mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc..Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc. there is stronger restraint, the most also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppression intestinal absorption cholesterol etc., its clinical application widely, can be used for treating respiratory tract infection, bacillary dysentery, acute urinary, dyslipidemia etc. more than 40 with other medicines compatibility and plant disease.
Herba portulacae: nature and flavor: cold in nature, sweet in the mouth acid.Gui Jing: enter heart channel, Liver Channel, spleen channel, large intestine channel.Function: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: pyretic toxicity dysentery, pyretic stranguria, urine retention, leucorrhea with red and white discharge, metrorrhagia, hemorrhoidal bleeding, skin infection carbuncle furuncle, erysipelas, scrofula, exudative dermatitis, the baldst, dysentery (defecate half-dried half dilute), toxic-heat and blood stasis, carbuncle furuncle, eczema, snake bite and insect sting, have blood in stool, metrostaxis, modern times are mostly used for treating enteritis, acute arthritis, cystitis, urethritis, anusitis, bleeding hemorrhoids etc..
Fructus Trichosanthis: antibacterial, antitumaous effect.Fructus Trichosanthis has some inhibitory action to escherichia coli, sonne bacillus, Bacillus proteus etc. in vitro.Infusion (1: 2) also has inhibitory action in various degree to some dermatophytes in vitro.In vitro in test, whole Fructus Trichosanthis decoct (20% decoct) has lethal effect to ascites cells.And it is believed that the fruit-rind of Chinese trichosanthes, semen trichosanthis are all effective, but the former effect is preferable.Plant shell the most invalid with fatty oil.Alcohol, ether extract is the most effective.60% alcohol extraction thing interaction in vitro is best.But animal experiment, its effect is the most significant, also unstable；In vivo, the effect that sarcoma acts on comparison ascites cells is strong.
Semen Cuscutae: base: for the herb of Convolvulaceae Hellweed Semen Cuscutae.Composition: Semen Cuscutae contains alkaloid, anthraquinone, coumarin, flavone, glycoside, sterol, tannic acid, saccharide etc..Flavonoid has: Quercetin, astragalin, hyperin；Sterols has: cholesterol, campesterol, cupreol, stigmasterol, β-Amyrin.Also containing trace element such as strontium, molybdenum, calcium, magnesium, ferrum, manganese, zinc, copper etc. and several amino acids (free amino acid in seed and the total amino acids after hydrolysis are 5.3%, and wherein the content of essential amino acids accounts for 42.8%).The property of medicine: micro-pungent, sweet, flat, nontoxic.Function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the disease such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of abdominal mass abdominal mass, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomitting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle；External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation.
Radix Panacis Quinquefolii: cool in nature, sweet in the mouth, micro-hardship.Function cures mainly: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.For deficiency of vital energy yin deficiency, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done.Lung benefiting is cloudy, clear asthenic fire, promoting the production of body fluid to quench thirst.Controlling deficiency of the lung chronic cough, lose blood, dry throat and mouth, deficiency-heat is tired of tired.
Radix Morindae Officinalis: Radix Morindae Officinalis (formal name used at school: Morinda officinalis How), for dicotyledon Rubiaceae, length 3～13cm, wide 1.5～5cm, front end is short tapering, base portion obtuse or circle.The dry root of Radix Morindae Officinalis, root is oblate cylindricality, slightly curved song.Main product is in the ground such as Guangdong, Guangxi.Medicinal plants, cure mainly that impotence and seminal emission, cold womb be infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity soft.
Cortex Lycii: nature and flavor: cold in nature, sweet in the mouth.Function cures mainly: removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.Interior-heat is quenched one's thirst.
Rhizoma Imperatae: return lung, stomach, bladder warp.Effect cooling blood for hemostasis, clearing away heat and promoting diuresis.Cure mainly and spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, cough due to lung-heat, gastropyretic vomiting, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.
Fructus Momordicae charantiae: reduce blood glucose effect.After rabbit that is normal and that suffer from alloxan diabetes gavages Fructus Momordicae charantiae juice, blood glucose can be made substantially to reduce.Subcutaneous injection anterior pituitary extractum causes the rat of hyperglycemia, and the water extract gavaging Fructus Momordicae charantiae juice also has the hypoglycemic effect of fall.Charantin being administered orally to rabbit and can reduce blood glucose, model of action is similar to tolbutamide and relatively strong, and the cat extracing pancreas is reduced blood glucose effect is not wholly absent, therefore its blood sugar lowering includes two kinds of effects to pancreas and non-pancreas.Also have and think that the dry extract of Fructus Momordicae charantiae juice and fruit is the most certain to the hypoglycemic activity of the rabbit of normal and diabetes.Diabetes patient is administered orally the alcoholic extract of Fructus Momordicae charantiae and does not reduce blood glucose.
Rice vinegar: rice vinegar is that numerous kinds vinegar Middle nutrition is worth higher one, containing abundant basic amino acid, glucide, organic acid, vitamin B1, vitamin B2, vitamin C, inorganic salt, mineral etc..
The present invention treats type ii diabetes and merges the vinegar beverage " emphasis entirety " of dyslipidemia, both can cure the disease, and can keep fit again to prevent disease, and this is the big feature being different from Drug therapy.And the vinegar beverage of this treatment type ii diabetes merging dyslipidemia is based entirely on Chinese medicine principle and is prepared from, more safe and reliable, without any side effects.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited by this.
Embodiment 1 one kinds is treated type ii diabetes and is merged the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from (every part takes 10g): 2 parts of Radix Glycyrrhizae, Fructus Hippophae 2 parts, Rhizoma Chuanxiong 6 parts, Flos Lonicerae 4 parts, Herba portulacae 5 parts, Fructus Trichosanthis 3 parts, Semen Cuscutae 1 part, Radix Salviae Miltiorrhizae 4 parts, Rhizoma Coptidis 7 parts, Radix Panacis Quinquefolii 3 parts, Radix Morindae Officinalis 8 parts, Cortex Lycii 5 parts, Rhizoma Imperatae 6 parts, 10 parts of Fructus Momordicae charantiae, rice vinegar 30 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 80 degrees Celsius, seal 1 minute, filter off filtrate, repeat above-mentioned step 2 time, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 2 times, drain away the water, grind, with soaking in rice vinegar 3 hours, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 6 minutes, dry in the air to crisp, grind to form smalls, cross 80 mesh sieves stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 20 minutes after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 6 minutes, it is fried open at intense fire, cross 160 mesh drainage screens after sealing and standing 2-6 hour, bottle and i.e. obtain vinegar beverage.
Embodiment 2 one kinds is treated type ii diabetes and is merged the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from (every part takes 10g): 6 parts of Radix Glycyrrhizae, Fructus Hippophae 6 parts, Rhizoma Chuanxiong 10 parts, Flos Lonicerae 8 parts, Herba portulacae 10 parts, Fructus Trichosanthis 7 parts, Semen Cuscutae 5 parts, Radix Salviae Miltiorrhizae 8 parts, Rhizoma Coptidis 12 parts, Radix Panacis Quinquefolii 5 parts, Radix Morindae Officinalis 14 parts, Cortex Lycii 15 parts, Rhizoma Imperatae 12 parts, 20 parts of Fructus Momordicae charantiae, rice vinegar 60 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, is pounded thick liquid stand-by:
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 100 degrees Celsius, seal 5 minutes, filter off filtrate, repeat the above steps 2 times, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 6 times, drain away the water, grind, with soaking in rice vinegar 8 hours, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 6 minutes, dry in the air to crisp, grind to form smalls, cross 120 mesh sieves stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 40 minutes after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 12 minutes, it is fried open at intense fire, sealing and standing crosses 200 mesh drainage screens after 6 hours, bottle and i.e. obtain vinegar beverage.
Embodiment 3 one kinds is treated type ii diabetes and is merged the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from (every part takes 10g): 3 parts of Radix Glycyrrhizae, Fructus Hippophae 3 parts, Rhizoma Chuanxiong 7 parts, Flos Lonicerae 5 parts, Herba portulacae 6 parts, Fructus Trichosanthis 4 parts, Semen Cuscutae 2 parts, Radix Salviae Miltiorrhizae 5 parts, Rhizoma Coptidis 9 parts, Radix Panacis Quinquefolii 3.5 parts, Radix Morindae Officinalis 10 parts, Cortex Lycii 8 parts, Rhizoma Imperatae 7 parts, 13 parts of Fructus Momordicae charantiae, rice vinegar 40 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 85 degrees Celsius, seal 2 minutes, filter off filtrate, repeat step 2 time, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 3 times, drain away the water, grind, with soaking in rice vinegar 5 hours, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 3 minutes, dry in the air to crisp, grind to form smalls, cross 90 mesh sieves stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 25 minutes after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 8 minutes, it is fried open at intense fire, sealing and standing crosses 170 mesh drainage screens after 3 hours, bottle and i.e. obtain vinegar beverage.
Embodiment 4 one kinds is treated type ii diabetes and is merged the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from (every part takes 10g): 5 parts of Radix Glycyrrhizae, Fructus Hippophae 5 parts, Rhizoma Chuanxiong 9 parts, Flos Lonicerae 7 parts, Herba portulacae 9 parts, Fructus Trichosanthis 6 parts, Semen Cuscutae 4 parts, Radix Salviae Miltiorrhizae 7 parts, Rhizoma Coptidis 11 parts, Radix Panacis Quinquefolii 4.5 parts, Radix Morindae Officinalis 12 parts, Cortex Lycii 13 parts, Rhizoma Imperatae 11 parts, 18 parts of Fructus Momordicae charantiae, rice vinegar 50 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 95 degrees Celsius, seal 4 minutes, filter off filtrate, repeat step 2 time, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 5 times, drain away the water, grind, with soaking in rice vinegar 7 hours, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 5 minutes, dry in the air to crisp, grind to form smalls, cross 110 mesh sieves stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 35 minutes after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 10 minutes, it is fried open at intense fire, sealing and standing crosses 190 mesh drainage screens after 5 hours, bottle and i.e. obtain vinegar beverage.
Embodiment 5 one kinds is treated type ii diabetes and is merged the vinegar beverage of dyslipidemia, takes off and states the primary raw material of weight proportion and be prepared from (every part takes 10g): 4 parts of Radix Glycyrrhizae, Fructus Hippophae 4 parts, Rhizoma Chuanxiong 8 parts, Flos Lonicerae 6 parts, Herba portulacae 7.5 parts, Fructus Trichosanthis 5 parts, Semen Cuscutae 3 parts, Radix Salviae Miltiorrhizae 6 parts, Rhizoma Coptidis 10 parts, Radix Panacis Quinquefolii 4 parts, Radix Morindae Officinalis 11 parts, Cortex Lycii 11 parts, Rhizoma Imperatae 9.5 parts, 15 parts of Fructus Momordicae charantiae, rice vinegar 45 parts.
Above-mentioned treatment type ii diabetes merges the preparation method of the vinegar beverage of dyslipidemia, and step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 90 degrees Celsius, seal 3 minutes, filter off filtrate, repeat the above steps 2 times, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis and Cortex Lycii are cleaned 4 times, drain away the water, grind, with soaking in rice vinegar 5.5 hours, filter, filtrate is standby, filtering residue is placed in the hot pot dryouied, repeatedly stir-fries 4 minutes, dry in the air to crisp, grind to form smalls, cross 100 mesh sieves stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly, boil in a covered pot over a slow fire 30 minutes after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, put into step (1) and (2) gained crude drug, stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 9 minutes, it is fried open at intense fire, sealing and standing crosses 180 mesh drainage screens after 4 hours, bottle and i.e. obtain vinegar beverage.
Test example 1 embodiment 5 gained treatment type ii diabetes merges the clinical practice of the vinegar beverage of dyslipidemia: we have randomly drawed 400 patients and have tested (400 patients have treatment type ii diabetes in various degree to merge dyslipidemia), it is divided into experimental group and matched group, wherein female 200 example, male 200 examples.Before test, this crowd carrying out Continuous Observation, record symptom and change, is randomly divided into two groups, experimental group and matched group, experimental group uses embodiment 5 products obtained therefrom, and matched group only merges the medicine of dyslipidemia with treatment type ii diabetes.
Using method: for making this medicine reach optimum therapeuticing effect, every time take vinegar beverage 30-50ml of the present invention, the morning, noon and afternoon the most once, 5 days are a course for the treatment of.
Curative effect situation criterion: 1, cure: using after this product, malaise symptoms all disappears, 2, effectively, after using this product, malaise symptoms alleviates or partial disappearance；3, invalid, after using this product, malaise symptoms is unchanged.We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result such as following table:
1: two group of Clinical efficacy comparison [example] table 1 of table
Table 1
Interpretation of result: experimental group all can reach to treat type ii diabetes within the observation period and merge effects on dyslipidemia with matched group, but the obvious effective rate of experimental group and total effective rate are apparently higher than matched group, and matched group have also appeared the case of untoward reaction, so the aspect that the embodiment of the present invention 5 gained vinegar beverage merges dyslipidemia at treatment type ii diabetes has significant curative effect, and all select in pure natural raw material through the suitable process of preparing Chinese medicine due to this product, easy to use, and it is without any side effects, also nervous system will not be caused burden, be not result in dependence and addiction.
Claims (10)
1. the vinegar beverage treating type ii diabetes merging dyslipidemia, it is characterised in that: take off and state the main of weight proportion
Raw material is prepared from: Radix Glycyrrhizae 2-6 part, Fructus Hippophae 2-6 part, Rhizoma Chuanxiong 6-10 part, Flos Lonicerae 4-8 part, Herba portulacae 5-10 part,
Fructus Trichosanthis 3-7 part, Semen Cuscutae 1-5 part, Radix Salviae Miltiorrhizae 4-8 part, Rhizoma Coptidis 7-12 part, Radix Panacis Quinquefolii 3-5 part, Radix Morindae Officinalis 8-14 part,
Cortex Lycii 5-15 part, Rhizoma Imperatae 6-12 part, Fructus Momordicae charantiae 10-20 part, rice vinegar 30-60 part.
Treatment type ii diabetes the most according to claim 1 merges the vinegar beverage of dyslipidemia, it is characterised in that: take off and state
The primary raw material of weight proportion is prepared from: Radix Glycyrrhizae 3-5 part, Fructus Hippophae 3-5 part, Rhizoma Chuanxiong 7-9 part, Flos Lonicerae 5-7 part,
Herba portulacae 6-9 part, Fructus Trichosanthis 4-6 part, Semen Cuscutae 2-4 part, Radix Salviae Miltiorrhizae 5-7 part, Rhizoma Coptidis 9-11 part, Radix Panacis Quinquefolii 3.5-4.5
Part, Radix Morindae Officinalis 10-12 part, Cortex Lycii 8-13 part, Rhizoma Imperatae 7-11 part, Fructus Momordicae charantiae 13-18 part, rice vinegar 40-50 part.
Treatment type ii diabetes the most according to claim 1 merges the vinegar beverage of dyslipidemia, it is characterised in that: take off and state
The primary raw material of weight proportion is prepared from: 4 parts of Radix Glycyrrhizae, Fructus Hippophae 4 parts, Rhizoma Chuanxiong 8 parts, Flos Lonicerae 6 parts, Herba portulacae 7.5
Part, Fructus Trichosanthis 5 parts, Semen Cuscutae 3 parts, Radix Salviae Miltiorrhizae 6 parts, Rhizoma Coptidis 10 parts, Radix Panacis Quinquefolii 4 parts, Radix Morindae Officinalis 11 parts, Cortex Lycii
11 parts, Rhizoma Imperatae 9.5 parts, 15 parts of Fructus Momordicae charantiae, rice vinegar 45 parts.
4. the preparation method of the vinegar beverage of dyslipidemia is merged according to the treatment type ii diabetes described in any one of claim 1-3,
It is characterized in that: step is as follows:
(1) fresh Fructus Trichosanthis is cleaned, stripping and slicing, be pounded thick liquid stand-by；
(2) Herba portulacae is rinsed well together with Fructus Momordicae charantiae, be cut into filament, add the hot water of 80-100 degree Celsius, seal 1-5
Minute, filter off filtrate, repeat the above steps 2 times, be pounded thick liquid and add Mel and mix thoroughly stand-by；
(3) by Radix Glycyrrhizae, Fructus Hippophae, Rhizoma Chuanxiong, Flos Lonicerae, Fructus Trichosanthis, Semen Cuscutae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Panacis Quinquefolii, Radix Morindae Officinalis
Cleaning 2-6 time with Cortex Lycii, drain away the water, grind, with soaking in rice vinegar 3-8 hour, filter, filtrate is standby, by filtering residue
It is placed in the hot pot dryouied, repeatedly stir-fries 2-6 minute, dry in the air to crisp, grind to form smalls, cross 80-120 mesh sieve stand-by；
(4) step (3) gained smalls Mel and dextrin are mixed thoroughly, pour in step (3) gained filtrate after mixing thoroughly,
Boil in a covered pot over a slow fire 20-40 minute after being stirred well to melt completely；
(5) step (4) gains big fire is heated rapidly to boiling, puts into step (1) and (2) gained crude drug,
Stir while slow fire boiling adds the concentration of clear water dilute liquid medicine after 6-12 minute, be fried open at intense fire, sealing and standing 2-6
Cross 160-200 mesh drainage screen after hour, bottle and i.e. obtain vinegar beverage.
Preparation method the most according to claim 4, it is characterised in that: step (2) adds the hot water of 85-95 degree Celsius,
Seal 2-4 minute (preferably, add the hot water of 90 degrees Celsius, seal 3 minutes).
Preparation method the most according to claim 4, it is characterised in that: step (3) is soaked 4-7 hour with vinegar and is filtered (excellent
Choosing, soak 5.5 hours with vinegar and filter).
Preparation method the most according to claim 4, it is characterised in that: step (3) stir-fries 3-5 minute repeatedly, dry in the air to
Crisp, grind to form smalls, 90-110 mesh sieve is stand-by excessively (preferably, repeatedly stir-fries 4 minutes, dries in the air to crisp, grind to form
Smalls, crosses 100 mesh sieves stand-by).
Preparation method the most according to claim 4, it is characterised in that: step (4) is stewing after being stirred well to melt completely
25-35 minute (preferably, boiling in a covered pot over a slow fire 30 minutes after being stirred well to melt completely).
Preparation method the most according to claim 4, it is characterised in that: step (5) stirs slow fire boiling 8-10
The concentration adding clear water dilute liquid medicine after minute (preferably, adds clear water dilute liquid medicine after stirring slow fire boiling 9 minutes
Concentration).
Preparation method the most according to claim 4, it is characterised in that: mistake after step (5) sealing and standing 3-5 hour
170-190 mesh drainage screen (preferably, sealing and standing crosses 180 mesh drainage screens after 4 hours).
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