CN104382047A - 一种绞股蓝益生菌咀嚼片及其制备方法 - Google Patents
一种绞股蓝益生菌咀嚼片及其制备方法 Download PDFInfo
- Publication number
- CN104382047A CN104382047A CN201410719435.1A CN201410719435A CN104382047A CN 104382047 A CN104382047 A CN 104382047A CN 201410719435 A CN201410719435 A CN 201410719435A CN 104382047 A CN104382047 A CN 104382047A
- Authority
- CN
- China
- Prior art keywords
- gynostemma pentaphylla
- powder
- preparation
- probiotic
- chewable tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000002956 Gynostemma pentaphyllum Nutrition 0.000 title claims abstract description 36
- 241001065361 Gynostemma Species 0.000 title claims abstract description 28
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 21
- 239000006041 probiotic Substances 0.000 title claims abstract description 13
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 13
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 230000000529 probiotic effect Effects 0.000 title abstract description 8
- 229940068682 chewable tablet Drugs 0.000 title abstract 6
- 239000000843 powder Substances 0.000 claims abstract description 23
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 4
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 4
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 4
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 4
- 235000020183 skimmed milk Nutrition 0.000 claims abstract description 4
- 239000003826 tablet Substances 0.000 claims abstract description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 240000006509 Gynostemma pentaphyllum Species 0.000 claims description 8
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims description 7
- 150000003271 galactooligosaccharides Chemical class 0.000 claims description 7
- 230000001580 bacterial effect Effects 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 5
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000000811 xylitol Substances 0.000 claims description 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 3
- 229960002675 xylitol Drugs 0.000 claims description 3
- 235000010447 xylitol Nutrition 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 7
- 239000008280 blood Substances 0.000 abstract description 6
- 210000004369 blood Anatomy 0.000 abstract description 6
- 230000000968 intestinal effect Effects 0.000 abstract description 5
- 210000004185 liver Anatomy 0.000 abstract description 5
- 230000004083 survival effect Effects 0.000 abstract description 4
- 206010028980 Neoplasm Diseases 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
- 235000013406 prebiotics Nutrition 0.000 description 3
- 230000003712 anti-aging effect Effects 0.000 description 2
- 230000002929 anti-fatigue Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 230000000767 anti-ulcer Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000037356 lipid metabolism Effects 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 241000303854 Aralia leschenaultii Species 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007907 direct compression Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229940089161 ginsenoside Drugs 0.000 description 1
- 229930182494 ginsenoside Natural products 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000009702 powder compression Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
本发明提供了一种绞股蓝益生菌咀嚼片及其制备方法，以绞股蓝浸膏粉、葡萄糖、乳糖、微晶纤维素、脱脂奶粉和益生菌菌粉按比例混合后。采用粉末直接压片法进行压片，最终得到益生菌片剂的生产配方和方法，以及使用该方法生产的一种含绞股蓝的活菌存活率极高的决咀嚼片。本发明优点在于：粉末直接压片法原料使用率高、工艺稳定、加工速度快、益生菌存活率高，且益生菌调节肠道菌群平衡、解酒护肝和增强免疫功效的功效与绞股蓝降血脂、降血糖、抗溃疡、抗肿瘤、抗衰老等作用相互叠加促进，是一种功效良好的咀嚼片保健品，适合规模化生产和市场销售。
Description
技术领域
本发明属于保健营养品技术领域，尤其涉及一种绞股蓝益生菌咀嚼片及其制备方法。
背景技术
绞股蓝为葫芦科多年生藤本植物，又名七叶胆、五叶参。绞股蓝人参皂苷的含量是人参的8倍之多，并且不会出现过量服用的副作用。现代药学研究证实绞股蓝具有降血脂、降血糖、抗溃疡、抗肿瘤、抗疲劳、抗衰老、保肝及增强免疫功能等作用，是一种新的药食两用植物资源。肠道是人体最大的免疫器官，益生菌可以调节肠道菌群平衡、提高机体免疫力、调节血脂代谢、保护肝脏、预防糖尿病、降低肿瘤等功效。直接压片法制得的绞股蓝益生菌咀嚼片，原料利用率高，益生菌存活率高，低聚半乳糖是具天然属性的功能性低聚糖，人体肠道中的益生乳酸菌菌群的繁衍和定植依赖于低聚糖的存在，低聚半乳糖作为益生元添加后，使益生菌在肠道定植和存活率增强。
发明内容
本发明提供了一种绞股蓝益生菌咀嚼片及其制备方法，本发明选用经过人体实验安全验证的具有较好益生功效的菌株，并联合添加中药成分绞股蓝和益生元低聚半乳糖。本发明采用的是粉末直接压片法，更加保证了原料的利用率，产品的稳定性及添加的益生菌的活性。
为实现上述发明目的，本发明采用以下技术方案予以实现：
一种绞股蓝益生菌咀嚼片的制备方法，它包括以下步骤：
(1)将绞股蓝中药进行粉碎，加入6-7倍于其重量的水，70℃浸提，每次提取时间60min，浸提3次，过滤机精滤，真空浓缩成稠浸膏，干燥至水分含量5%以下，打碎制成粉末，过100目筛，得到绞股蓝浸膏粉；
(2)将以下组分捣碎过100目筛，并按照质量百分比配制：微晶纤维素35%、脱脂奶粉35 %、绞股蓝浸膏粉12 %、木糖醇10 %、低聚半乳糖 3 %、柠檬酸3 %、益生菌菌粉2 %；
(3)将混匀的粉末直接单冲压片，调节压力为20-40KN，得到一种绞股蓝益生菌咀嚼片。
与现有技术相比，本发明的优点和技术效果是：本发明所述咀嚼片中添加了绞股蓝浸膏粉，绞股蓝具有降血脂、降血糖、抗溃疡、抗肿瘤、抗疲劳、抗衰老、保肝及增强免疫功能等作用。低聚半乳糖作为益生元的添加，使益生菌群的繁衍和定植能力增强，更好地发挥益生菌调节肠道菌群、提高机体免疫力、调节血脂代谢、保护肝脏、预防糖尿病、降低肿瘤发生风险的功效。
本发明所述绞股蓝益生菌咀嚼片具有优良的市场应用前景，本发明为绞股蓝益生菌咀嚼片产品的开发提供了可能。
具体实施方式
下面结合实施例对本发明的技术方案进行详细说明。
实施例1
本发明所述咀嚼片的制备方法如下：
1、将绞股蓝中药进行粉碎，加入6-7倍于其重量的水，70℃浸提，每次提取时间60min，浸提3次，过滤机精滤，真空浓缩成稠浸膏，干燥至水分含量5%以下，打碎制成粉末，过100目筛，得到绞股蓝浸膏粉。
2、将以下组分捣碎过100目筛，并按照质量百分比配制：微晶纤维素35%、脱脂奶粉35 %、绞股蓝浸膏粉12 %、木糖醇10 %、低聚半乳糖 3 %、柠檬酸3 %、益生菌菌粉2 %。
3、将混匀的粉末直接单冲压片，调节压力为20-40KN，得到一种绞股蓝益生菌咀嚼片。
以上实施例仅用以说明本发明的技术方案，而非对其进行限制；尽管参照前述实施例对本发明进行了详细的说明，对于本领域的普通技术人员来说，依然可以对前述实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而这些修改或替换，并不使相应技术方案的本质脱离本发明所要求保护的技术方案的精神和范围。
Claims (3)
1.一种绞股蓝益生菌咀嚼片的制备方法，其特征在于它包括以下步骤：
(1)将绞股蓝中药进行粉碎，加入6-7倍于其重量的水，70℃浸提，每次提取时间60min，浸提3次，过滤机精滤，真空浓缩成稠浸膏，干燥至水分含量5%以下，打碎制成粉末，过100目筛，得到绞股蓝浸膏粉；
(2)将以下组分捣碎过100目筛，并按照质量百分比配制：微晶纤维素35%、脱脂奶粉35 %、绞股蓝浸膏粉12 %、木糖醇10 %、低聚半乳糖 3 %、柠檬酸3 %、益生菌菌粉2 %；
(3)将混匀的粉末直接单冲压片，调节压力为20-40KN，得到一种绞股蓝益生菌咀嚼片。
2.根据权利要求1所述的绞股蓝益生菌咀嚼片的制备方法，其特征在于添加了绞股蓝浸膏粉和益生菌菌粉所附加的保健功效。
3.根据权利要求1或2所述的制备方法制得的绞股蓝益生菌咀嚼片。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410719435.1A CN104382047A (zh) | 2014-12-03 | 2014-12-03 | 一种绞股蓝益生菌咀嚼片及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410719435.1A CN104382047A (zh) | 2014-12-03 | 2014-12-03 | 一种绞股蓝益生菌咀嚼片及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104382047A true CN104382047A (zh) | 2015-03-04 |
Family
ID=52600095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410719435.1A Pending CN104382047A (zh) | 2014-12-03 | 2014-12-03 | 一种绞股蓝益生菌咀嚼片及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104382047A (zh) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106616602A (zh) * | 2016-12-09 | 2017-05-10 | 宁夏沃福百瑞枸杞产业股份有限公司 | 一种黑枸杞益生菌片的制备方法 |
| CN107753547A (zh) * | 2016-11-17 | 2018-03-06 | 北京工商大学 | 改善肠道菌群的皂苷类化合物、制备方法及其应用 |
| CN109363160A (zh) * | 2018-10-15 | 2019-02-22 | 安徽科技学院 | 一种铜陵白姜益生菌咀嚼片及其制备方法 |
-
2014
- 2014-12-03 CN CN201410719435.1A patent/CN104382047A/zh active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753547A (zh) * | 2016-11-17 | 2018-03-06 | 北京工商大学 | 改善肠道菌群的皂苷类化合物、制备方法及其应用 |
| WO2018090983A1 (zh) * | 2016-11-17 | 2018-05-24 | 北京工商大学 | 改善肠道菌群的皂苷类化合物、制备方法及其应用 |
| CN106616602A (zh) * | 2016-12-09 | 2017-05-10 | 宁夏沃福百瑞枸杞产业股份有限公司 | 一种黑枸杞益生菌片的制备方法 |
| CN109363160A (zh) * | 2018-10-15 | 2019-02-22 | 安徽科技学院 | 一种铜陵白姜益生菌咀嚼片及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104026446B (zh) | 一种适合于高血糖人群服用的营养代餐粉及其制备方法 | |
| CN1762236B (zh) | 一种能增强人体免疫力的保健食品及其制备方法 | |
| CN105085695A (zh) | 一种铁皮石斛浸膏粉制备方法 | |
| CN101589801B (zh) | 一种红参蜜片的制作工艺 | |
| CN102669225A (zh) | 花香口味月饼 | |
| CN103494191B (zh) | 玉竹人参口服液的制备方法 | |
| CN107136506A (zh) | 一种具有降血压功效的黑果腺肋花楸片及其制备方法 | |
| CN103584102A (zh) | 一种具有辅助降血糖作用的保健食品及其制备方法 | |
| CN103340340A (zh) | 提高免疫力的保健食品 | |
| CN104366649A (zh) | 一种含益生菌和低聚糖的固体饮料及其制备方法 | |
| CN102703293A (zh) | 一种黑大蒜酒及制备方法 | |
| CN102948748A (zh) | 一种抗疲劳的保健品 | |
| CN104382047A (zh) | 一种绞股蓝益生菌咀嚼片及其制备方法 | |
| CN104187681B (zh) | 一种降血糖降血脂保健食品及其制备方法 | |
| CN105707637A (zh) | 一种降糖固体饮料及其制备方法 | |
| CN105595337A (zh) | 一种辅助降血糖海藻胶软胶囊及其制备方法 | |
| CN104643069B (zh) | 一种复方保健组合物及其制备方法 | |
| CN105559068A (zh) | 一种利用食药真菌发酵三叶青获得的组合物及其制备方法 | |
| CN105031289A (zh) | 一种铁皮石斛灵芝胶囊及其制备方法 | |
| CN104606451A (zh) | 一种降低餐后血糖(igt状态)的药食两用组合物及制备方法 | |
| CN104382002A (zh) | 一种缓解疲劳的玛咖片 | |
| CN104522662A (zh) | 红曲菌丝体复方降血糖功能食品及其制备方法 | |
| CN103431100B (zh) | 一种具有保健养生作用的芦笋饮料 | |
| CN103300381A (zh) | 一种保健颗粒冲剂及其制备方法 | |
| CN102356799B (zh) | 蜂胶糖 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150304 |
|
| WD01 | Invention patent application deemed withdrawn after publication |