CN104381263B - A kind of cream preparation of bactericidal composition - Google Patents
A kind of cream preparation of bactericidal composition Download PDFInfo
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- CN104381263B CN104381263B CN201410631358.4A CN201410631358A CN104381263B CN 104381263 B CN104381263 B CN 104381263B CN 201410631358 A CN201410631358 A CN 201410631358A CN 104381263 B CN104381263 B CN 104381263B
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- bactericidal composition
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Abstract
The present invention relates to the cream preparation of a kind of bactericidal composition.In bactericidal composition of the present invention, effective active composition Fenamidone, the mutual mixture of Ningnanmycin will not produce conflict；Compare single component and have synergistic effect, fungicidal spectrum can be expanded, be greatly improved the preventive effect to disease；Drug effect is more longlasting, and quick-acting is compared single dose and is also greatly improved；Having delayed drug-fast generation, low-residual, degradable in soil after the lasting period, consumption is few, to more environment-friendly, meets the requirement of agricultural production；To crop safety.The present composition disease to the preventing and treating agricultural crops such as vegetables, cereal crop, fruit tree, especially to preventing and treating downy mildew, epidemic disease, powdery mildew have special efficacy.
Description
Technical field
The present invention relates to bactericidal composition technical field, be specifically related to the cream preparation of a kind of bactericidal composition.
Background technology
Fenamidone chemical name: (S)-5-methyl-2-methyl mercapto-5-phenyl-3-anilino--3,5-glyoxalidine-4-ketone, structural formula is
, belong to imidazolone type, white powdery solid, fusing point is 137 DEG C, and density is 1.285, vapour pressure 3.4 × 10-7Pa(25 DEG C), solubility (20 DEG C): 7.8mg/l in water.Mitochondrial respiratory inhibitor.Have tag, permeate, systemic activity, there is good protection and therapeutic activity.Preventing and treating, by the microbial downy mildew of Oomycete cause of disease, epidemic disease (including early blight and late blight) etc., also has good activity to fruit tree black spot.
Ningnanmycin belongs to low toxicity Antibiotics bactericide, the innovation biological pesticide succeeded in developing by Chengdu Inst. of Biology, Chinese Academy of Sciences, tobacco mosaic virus disease, tomato virus disease, pepper virus disease, rice seedling blight, root rot, stripe disease, alternaria leaf spot of apple, powdery mildew of cucumber achieve registration, this external preventing and treating sclerotinia rot of colza, peronophythora litchi, large scale application the most in the multiple diseases such as other crop virosis, stem rot, blight dis-ease, powdery mildew.
Both the above medicine is after long-term being used alone, plant germ is the most easily made to develop immunity to drugs, causing the problems such as dosage increasing, preventive effect reduction, lasting period shortening, the Reusability of agricultural chemicals causes agricultural chemicals degradation rate in soil to decline, and is unfavorable for very much environment sustainable development.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides the cream preparation of a kind of bactericidal composition.In bactericidal composition of the present invention, effective active composition Fenamidone, the mutual mixture of Ningnanmycin will not produce conflict；Compare single component and have synergistic effect, fungicidal spectrum can be expanded, be greatly improved the preventive effect to disease；Drug effect is more longlasting, and quick-acting is compared single dose and is also greatly improved；Having delayed drug-fast generation, low-residual, degradable in soil after the lasting period, consumption is few, to more environment-friendly, meets the requirement of agricultural production；To crop safety.The present composition disease to the preventing and treating agricultural crops such as vegetables, cereal crop, fruit tree, especially to preventing and treating downy mildew, epidemic disease, powdery mildew have special efficacy.
The cream preparation of a kind of bactericidal composition of the present invention is to be realized by following technical scheme: the active ingredient of described bactericidal composition includes: Fenamidone, Ningnanmycin.
Described Fenamidone, the part by weight of Ningnanmycin are 1-20:1-20.
Fenamidone, the part by weight of Ningnanmycin are 5-10:1:5.
Preferably, Fenamidone, the part by weight of Ningnanmycin are 7:3.
Fenamidone in bactericidal composition, Ningnanmycin account for 60-90 part of bactericidal composition gross mass, also include emulsifying agent 3-20 part, solvent 20-55 part.
Fenamidone, Ningnanmycin are dissolved in a solvent, adds emulsifying agent, be uniformly mixed the cream preparation i.e. preparing this bactericidal composition.
Described emulsifying agent is aliphatic acid polyethenoxy base ester.
Described solvent is isopropanol.
The cream preparation of this bactericidal composition is for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree.
Beneficial effects of the present invention:
(1) present composition effective active composition Fenamidone, both Ningnanmycins mutually mixture will not produce conflict；
(2) present composition compares single component synergistic effect, can expand fungicidal spectrum, is greatly improved the preventive effect to disease；
(3) drug effect is more longlasting, and quick-acting is compared single dose and is also greatly improved；
(4) delay drug-fast generation, decreased agricultural chemicals Reusability number of times, reduced Pesticide use amount, reduce the use cost of agricultural chemicals；
(5) low-residual, degradable in soil after the lasting period, consumption is few, to more environment-friendly, meets the requirement of agricultural production；
(6) present composition disease to the preventing and treating agricultural crops such as vegetables, cereal crop, fruit tree, especially to preventing and treating downy mildew, epidemic disease, powdery mildew have special efficacy.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about the present invention, but and is not so limited the present invention.
Embodiment 1
The cream preparation of a kind of bactericidal composition of the present invention, containing Fenamidone 56 parts by weight, Ningnanmycin 24 parts, emulsifying agent 12 parts, solvent 40 parts.
Fenamidone, Ningnanmycin are dissolved in a solvent, adds emulsifying agent, be uniformly mixed the cream preparation i.e. preparing this bactericidal composition.
Described emulsifying agent is aliphatic acid polyethenoxy base ester.
Described solvent is isopropanol.
The cream preparation of this bactericidal composition is for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree.
Embodiment 2
The cream preparation of a kind of bactericidal composition of the present invention, containing Fenamidone 42 parts by weight, Ningnanmycin 18 parts, emulsifying agent 6 parts, solvent 25 parts.
Fenamidone, Ningnanmycin are dissolved in a solvent, adds emulsifying agent, be uniformly mixed the cream preparation i.e. preparing this bactericidal composition.
Described emulsifying agent is aliphatic acid polyethenoxy base ester.
Described solvent is isopropanol.
The cream preparation of this bactericidal composition is for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree.
Embodiment 3
The cream preparation of a kind of bactericidal composition of the present invention, containing Fenamidone 45 parts by weight, Ningnanmycin 45 parts, emulsifying agent 20 parts, solvent 55 parts.
Fenamidone, Ningnanmycin are dissolved in a solvent, adds emulsifying agent, be uniformly mixed the cream preparation i.e. preparing this bactericidal composition.
Described emulsifying agent is aliphatic acid polyethenoxy base ester.
Described solvent is isopropanol.
The cream preparation of this bactericidal composition is for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree.
Embodiment 4
Field test measures the prevention effect to downy mildew of garpe
Test dispenser twice altogether, check plot spray equivalent clear water.Spouting liquid is 45-60kg/667m2, continuous dispenser twice, 10 days intervals, liquid is sprayed application to uniformly crop complete stool.
The warmhouse booth selecting occurring degree medium is that experimental field soil fertility is medium, and irrigation and drainage are convenient.Using bilinear sampling method, every community takes 5 points, looks into 5 caves at every, and during investigation, 2 blades in the fixing middle part of every strain carry out fixed point inspection.
Sick leaf rate %: randomly select 100 blades, sick leaf accounts for the percentage of total leaf number.
Amount-experimental group disease leaf increments that preventive effect %:(control group disease leaf increases)/control group disease leaf increments * 100.
Poisoning is investigated
After dispenser, whether continuous 7d range estimation medicament has poisoning to crop.
Field control effectiveness test result of the test
Preventive effect investigation in 10 days after 1st medicine, 10 days and preventive effect investigation in 20 days after 2 medicines.
The effect of downy mildew of garpe prevented and treated by table 1
。
Table 1 is it can be seen that embodiment 1, embodiment 2 effect of preventing and treating downy mildew of garpe is the most notable.Observing during test, it, to grape safety, does not produces harmful effect.
Embodiment 5
Field test measures prevention effect to paddy rice powdery mildew, experimental procedure, prevents and treats parameter, poisoning investigation with described in embodiment 4,
The effect of paddy rice powdery mildew prevented and treated by table 2
。
Table 2 is it can be seen that embodiment 1, embodiment 2 effect of preventing and treating paddy rice powdery mildew is the most notable.Observing during test, it does not produces harmful effect to rice safety.
In sum, the cream preparation of this bactericidal composition of the present invention all has preferable prevention effect for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree, especially the prevention effect of downy mildew and powdery mildew is highlighted, and it is to Target crops safety.Compared with single dose, it is long that bactericidal composition of the present invention has the lasting period, easy to use, the advantage being not likely to produce poisoning.
Claims (1)
1. the cream preparation of a bactericidal composition, it is characterised in that containing Fenamidone 56 parts by weight, Ningnanmycin 24 parts, emulsifying agent 12 parts, solvent 40 parts；
Fenamidone, Ningnanmycin are dissolved in a solvent, adds emulsifying agent, be uniformly mixed the cream preparation i.e. preparing this bactericidal composition；
Described emulsifying agent is aliphatic acid polyethenoxy base ester；
Described solvent is isopropanol；
The cream preparation of this bactericidal composition is for preventing and treating the downy mildew of crop, epidemic disease, the powdery mildew diseases such as agricultural vegetables, cereal crop, fruit tree.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410631358.4A CN104381263B (en) | 2014-11-12 | 2014-11-12 | A kind of cream preparation of bactericidal composition |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410631358.4A CN104381263B (en) | 2014-11-12 | 2014-11-12 | A kind of cream preparation of bactericidal composition |
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| Publication Number | Publication Date |
|---|---|
| CN104381263A CN104381263A (en) | 2015-03-04 |
| CN104381263B true CN104381263B (en) | 2016-08-24 |
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| CN201410631358.4A Expired - Fee Related CN104381263B (en) | 2014-11-12 | 2014-11-12 | A kind of cream preparation of bactericidal composition |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015160619A1 (en) * | 2014-04-16 | 2015-10-22 | Bayer Cropscience Lp | Compositions comprising ningnanmycin and a fungicide |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816305A (en) * | 2010-05-09 | 2010-09-01 | 海南正业中农高科股份有限公司 | Bactericide pesticide composite containing oligochitosan |
| CN103190421A (en) * | 2013-04-07 | 2013-07-10 | 海南正业中农高科股份有限公司 | Cyflufenamid-containing sterilizing composite |
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2014
- 2014-11-12 CN CN201410631358.4A patent/CN104381263B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816305A (en) * | 2010-05-09 | 2010-09-01 | 海南正业中农高科股份有限公司 | Bactericide pesticide composite containing oligochitosan |
| CN103190421A (en) * | 2013-04-07 | 2013-07-10 | 海南正业中农高科股份有限公司 | Cyflufenamid-containing sterilizing composite |
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| CN104381263A (en) | 2015-03-04 |
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Inventor after: Wang Guobin Inventor before: Chi Zonglei Inventor before: Cang Weigong Inventor before: Ding Zhenyang |
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Effective date of registration: 20160713 Address after: 226112 Jiangsu city of Nantong Province Haimen Samsung town Dieshiqiao Island Road No. 188 Applicant after: NANTONG FANGDU ESTATE CO., LTD. Address before: Watson Road, Licheng District 250100 in Shandong city of Ji'nan province No. 389 building 401. Applicant before: JINAN CAVIN BIOTECHNOLOGY CO., LTD. |
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