CN104288457A - Traditional Chinese medicine oral liquid for treating pullorum disease - Google Patents
Traditional Chinese medicine oral liquid for treating pullorum disease Download PDFInfo
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- CN104288457A CN104288457A CN201410461665.2A CN201410461665A CN104288457A CN 104288457 A CN104288457 A CN 104288457A CN 201410461665 A CN201410461665 A CN 201410461665A CN 104288457 A CN104288457 A CN 104288457A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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Abstract
The invention relates to traditional Chinese medicine oral liquid for treating pullorum disease. The traditional Chinese medicine oral liquid is prepared by extracting eight traditional Chinese medicines such as the root of Chinese pulsatilla, Meadowrue Root and Rhizome, garlic, dandelion, honeysuckle, herba epimedii, liquorice and myrobalan. The product disclosed by the invention is diluted to be drunk by chicken by using drinking water according to a ratio of 1 to 20, and the oral liquid is taken once per day and is continuously taken for a week, so that the symptoms such as dispirited mind, retracted head, sagging wings, and defecation of white pasty loose stool of chicken can be treated and improved. The Chinese herbal medicine preparation has the characteristics of high functionality, small toxic and side effects, low drug residue amount, difficulty in drug resistance and the like and is suitable for the requirements on intensified group breeding and prevention in chicken houses and production of green foods.
Description
Technical field
The present invention relates to a kind of veterinary formulations, be specifically related to a kind of Chinese medicine oral liquid for the treatment of Pullorum Disease.
Background technology
Pullorum Disease is a kind of bacterial infectious disease, mainly encroaches on chickling, take Hakuri as feature, the ill rear many mortalities in two weeks of chickling.Primary disease is often widely current all over the world, forms serious threat to the development of poultry husbandry.The generation of current Pullorum Disease is day by day serious, and its fatality rate reaches 10% ~ 60%, more serious in stage harm of brooding especially, carrys out huge economic loss often to poultry industrial belt.In Pullorum Disease is prevented and treated, traditional method uses antibiotics.But due to the generation of drug resistance, antibiotic accumulates in vivo, caused the harm to chicken health, and excessive antibiotic is excreted to the environmental pollution caused in environment, and then also can impacts human health.
Chinese herbal medicine is natural prodcuts, maintains natural form and the biological activity of various material, has wide material sources, and functional strong, the feature such as toxic and side effects is little, drug residue is low, not easily develop immunity to drugs, is with a wide range of applications.According to incompletely statistics, in more than the 1000 kind of Chinese herbal medicine that current veterinary clinic uses, there is more than 200 kind to be utilized as raw materials of feed additives, be applicable to intensive farm group support group and prevent and produce the requirement of pollution-free food.
Summary of the invention
The invention provides a kind of veterinary formulations, for prevention and therapy Pullorum Disease, reduce mortality rate, improve fanning economics and foodsafety.The present invention is achieved in that
A kind of Chinese medicine oral liquid for the treatment of Pullorum Disease, it is characterized in that, it is made up of the raw material of following parts by weight: the Radix Pulsatillae 1 ~ 15 part, Radix et Rhizoma Thalictri 1 ~ 15 part, 1 ~ 5 part, Bulbus Allii, Herba Taraxaci 1 ~ 15 part, Flos Lonicerae 1 ~ 15 part, Herba Epimedii 1 ~ 10 part, 1 ~ 10 part, Radix Glycyrrhizae, Fructus Chebulae 1 ~ 15 part.
Formula of the present invention is by weight more preferably: the Radix Pulsatillae 15 parts, Radix et Rhizoma Thalictri 10 parts, 5 parts, Bulbus Allii, Herba Taraxaci 10 parts, Flos Lonicerae 10 parts, Herba Epimedii 5 parts, 10 parts, Radix Glycyrrhizae, Fructus Chebulae 10 parts.
The above-mentioned concrete method for making of oral liquid formulations of the present invention is as follows: by the Chinese herbal medicine of formula ratio, the Radix Pulsatillae (section), Radix et Rhizoma Thalictri, Bulbus Allii, Herba Taraxaci (cutting), Flos Lonicerae, Herba Epimedii, Radix Glycyrrhizae (cutting), Fructus Chebulae's (Universalpulverizer coarse powder) carry out pretreatment, remove the impurity in each component, after cleaning process, add in extraction pot and decoct.The Chinese medicine more than handled well adds drinking water and decocts three times, first time adds 10 times amount drinking waters and decocts 2 hours (after boiling), and second and third time adds 7 times amount drinking waters and decoct, and the time is each 1 hour (after boiling), collecting decoction, filter, filtrate reduced in volume is about 1.08 ~ 1.1 to relative density, adjust ph to 6.8 ~ 7.0, filter, sterilizing, subpackage, to obtain final product.
The compound preparation that the present invention is above-mentioned, can also comprise following pharmacopedics can adjuvant: as antiseptic, sweeting agent, correctives etc.
Using method of the present invention is: product of the present invention drinks to chicken group in after the dilution of 1:20 ratio drinking water, and 1 time on the one, be used in conjunction one week, can improve and treat disease chicken down in spirits, drop-head, wing is sagging, draws the symptoms such as stock white pasty state loose stool.
Prescription of the present invention each Chinese medicine ingredients effect is as follows:
The Radix Pulsatillae: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, has inhibitory action to staphylococcus aureus, bacillus pyocyaneus, dysentery bacterium, salmonella etc.
Radix et Rhizoma Thalictri: heat-clearing and toxic substances removing dysentery relieving is extremely sensitive medicine to Pullorum Disease salmonella.
Bulbus Allii: treatment bacillary dysentery.Bulbus Allii has inhibitory action to dysentery bacterium, can improve palatability in we simultaneously, increases appetite, improves feed intake.
Herba Taraxaci: heat-clearing and toxic substances removing, antiinflammatory.
Flos Lonicerae: heat-clearing and toxic substances removing dysentery relieving, has inhibitory action to the multiple of poultry to sick pathogenic bacteria, virus.Goodish effect is all had to the disease such as the epidemic febrile disease heating of prevention and therapy animal, anemopyretic cold, laryngopharyngitis, pneumonia, dysentery, swollen ulcer, erysipelas, cellulitis in animal feeding process.The effect strengthening this prescription is had in we.
Radix Glycyrrhizae: function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.Have the effect of the mediation property of medicine, normal and Flos Lonicerae prescription is same to be used.
Herba Epimedii: strengthening by means of tonics, strengthens disease chicken premunition.
Fructus Chebulae: comparatively strong to dysentery bacterium, bacillus pyocyaneus effect, to staphylococcus aureus, escherichia coli, streptococcus pneumoniae, Hemolytic streptococcus, has inhibitory action.
Above-mentioned crude drug or material combination use by the present invention, can improve effect of Chinese medicine ingredients to greatest extent, play complementary and castering action, the preventive and therapeutic action played, and reduce the mortality rate that Pullorum Disease suffers from chicken, improve fanning economics.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine oral liquid for Pullorum Disease, it is made up of the raw material of following parts by weight: the Radix Pulsatillae 15 parts, Radix et Rhizoma Thalictri 8 parts, 4 parts, Bulbus Allii, Herba Taraxaci 10 parts, Flos Lonicerae 12 parts, Herba Epimedii 8 parts, 6 parts, Radix Glycyrrhizae, Fructus Chebulae 10 parts.
Preparation process is as follows: by the Chinese herbal medicine of formula ratio, the Radix Pulsatillae (section), Radix et Rhizoma Thalictri, Bulbus Allii, Herba Taraxaci (cutting), Flos Lonicerae, Herba Epimedii, Radix Glycyrrhizae (cutting), Fructus Chebulae's (Universalpulverizer coarse powder) carry out pretreatment, remove the impurity in each component, after cleaning process, add in extraction pot and decoct.The Chinese medicine more than handled well adds drinking water and decocts three times, first time adds 10 times amount drinking waters and decocts 2 hours (after boiling), and second and third time adds 7 times amount drinking waters and decoct, and the time is each 1 hour (after boiling), collecting decoction, filter, filtrate reduced in volume is about 1.08 ~ 1.1 to relative density, adjust ph to 6.8 ~ 7.0, filter, sterilizing, subpackage, to obtain final product.
Nanjing raiser cultivates about 2000 chickling, has 100 priorities to occur lassitude, be afraid of cold, shiver with cold in the recent period.Feather is inverse vertical, and appetite is absolutely useless.Row's thick white feces, perianal feather has Calx sample feces pickup, and even block anus, the course of disease about has about 2 days, dead 9.Raiser has used furazolidone (0.4%), chloromycetin (0.2%) spice to use, but poor effect.Integrated culture family describe, more sick chicken is observed, diagnostic analysis is the Pullorum Disease that Salmonella causes.Suggestion raiser uses Chinese medicine oral liquid of the present invention, and carry out drinking-water treatment after 1:20 dilution, next day, being namely clearly better appearred in situation, basic rehabilitation afterwards on the 4th, anosis chicken death phenomenon in use Chinese herbal oral medicine therapeutic process of the present invention.
Embodiment 2:
Treat a Chinese medicine oral liquid for Pullorum Disease, it is made up of the raw material of following parts by weight: the Radix Pulsatillae 12 parts, Radix et Rhizoma Thalictri 10 parts, 5 parts, Bulbus Allii, Herba Taraxaci 10 parts, Flos Lonicerae 15 parts, Herba Epimedii 9 parts, 5 parts, Radix Glycyrrhizae, Fructus Chebulae 8 parts.
Preparation process is as follows: by the Chinese herbal medicine of formula ratio, the Radix Pulsatillae (section), Radix et Rhizoma Thalictri, Bulbus Allii, Herba Taraxaci (cutting), Flos Lonicerae, Herba Epimedii, Radix Glycyrrhizae (cutting), Fructus Chebulae's (Universalpulverizer coarse powder) carry out pretreatment, remove the impurity in each component, after cleaning process, add in extraction pot and decoct.The Chinese medicine more than handled well adds drinking water and decocts three times, first time adds 10 times amount drinking waters and decocts 2 hours (after boiling), and second and third time adds 7 times amount drinking waters and decoct, and the time is each 1 hour (after boiling), collecting decoction, filter, filtrate reduced in volume is about 1.08 ~ 1.1 to relative density, adjust ph to 6.8 ~ 7.0, filter, sterilizing, subpackage, to obtain final product.
About Nantong raiser cultivates 50 ages in days, about 2400 Growing Chicken, have 90 priorities to occur that lassitude, appetite are poor, the symptom of dysentery in the recent period, the course of disease about has about 4 days, dead 5.Cut open inspection to the sick chicken of death, naked eyes are visible as the disease states that Pullorum Disease causes.In pathogenic process, raiser uses with oxytetracycline spice, and effect is not ideal enough.Suggestion raiser uses Chinese medicine oral liquid of the present invention, and carry out drinking-water treatment after 1:20 dilution, after 2 days, being namely clearly better appears in situation, the basic rehabilitation of ill sick chicken after 5 days.
Be described in detail specific embodiments of the invention above, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and substituting also all among category of the present invention.Therefore, not departing from the equalization conversion and amendment done under spirit of the present invention and category, all should contain within the scope of the invention.
Claims (2)
1. treat the Chinese medicine oral liquid of Pullorum Disease for one kind, it is characterized in that, it is made up of the raw material of following weight: the Radix Pulsatillae 1 ~ 15 part, Radix et Rhizoma Thalictri 1 ~ 15 part, 1 ~ 5 part, Bulbus Allii, Herba Taraxaci 1 ~ 15 part, part Flos Lonicerae 1 ~ 15 part, part Herba Epimedii 1 ~ 10 part, 1 ~ 10 part, Radix Glycyrrhizae, Fructus Chebulae 1 ~ 15 part.
2. a kind of Chinese medicine oral liquid for the treatment of Pullorum Disease as claimed in claim 1, its formula by weight more preferably: the Radix Pulsatillae 15 parts, Radix et Rhizoma Thalictri 10 parts, 5 parts, Bulbus Allii, Herba Taraxaci 10 parts, Flos Lonicerae 10 parts, Herba Epimedii 5 parts, 10 parts, Radix Glycyrrhizae, Fructus Chebulae 10 parts.
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| CN201410461665.2A CN104288457A (en) | 2014-09-12 | 2014-09-12 | Traditional Chinese medicine oral liquid for treating pullorum disease |
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| CN201410461665.2A CN104288457A (en) | 2014-09-12 | 2014-09-12 | Traditional Chinese medicine oral liquid for treating pullorum disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106983815A (en) * | 2017-04-13 | 2017-07-28 | 南宁市健佳网络科技有限公司 | It is a kind of to treat medicine of white diarrhea and preparation method thereof |
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| CN102860418A (en) * | 2012-09-19 | 2013-01-09 | 漳州大北农农牧科技有限公司 | Preparation method and application of composite probiotics fermentation Chinese medicinal herb composite feed additive |
| CN102949650A (en) * | 2012-11-16 | 2013-03-06 | 旌德县鸿雁养殖有限公司 | Traditional Chinese medicine for curing white diarrhea of young geese, preparation and using method |
| CN102988548A (en) * | 2011-09-19 | 2013-03-27 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with function of astringing intestine to stop diarrhea, preparation method thereof |
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2014
- 2014-09-12 CN CN201410461665.2A patent/CN104288457A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100100019A (en) * | 2009-03-05 | 2010-09-15 | 원광대학교산학협력단 | A veterinary composition comprising extracts of galla rhois showing antibacterial activity against helicobacter species |
| CN102988548A (en) * | 2011-09-19 | 2013-03-27 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with function of astringing intestine to stop diarrhea, preparation method thereof |
| CN102860418A (en) * | 2012-09-19 | 2013-01-09 | 漳州大北农农牧科技有限公司 | Preparation method and application of composite probiotics fermentation Chinese medicinal herb composite feed additive |
| CN102949650A (en) * | 2012-11-16 | 2013-03-06 | 旌德县鸿雁养殖有限公司 | Traditional Chinese medicine for curing white diarrhea of young geese, preparation and using method |
Non-Patent Citations (1)
| Title |
|---|
| 李邦模等: "《养鸡秘诀》", 30 April 2004 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106983815A (en) * | 2017-04-13 | 2017-07-28 | 南宁市健佳网络科技有限公司 | It is a kind of to treat medicine of white diarrhea and preparation method thereof |
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Application publication date: 20150121 |