CN104288119A - 稳定化的吡铂口服剂型 - Google Patents

稳定化的吡铂口服剂型 Download PDF

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Publication number
CN104288119A
CN104288119A CN201410283507.2A CN201410283507A CN104288119A CN 104288119 A CN104288119 A CN 104288119A CN 201410283507 A CN201410283507 A CN 201410283507A CN 104288119 A CN104288119 A CN 104288119A
Authority
CN
China
Prior art keywords
picoplatin
core
coating
dosage form
peroral dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410283507.2A
Other languages
English (en)
Chinese (zh)
Inventor
A·J·利
C·A·普罗西夏伊
E·S·Y·王
C·M·吉安多米尼科
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poniard Pharmaceuticals Inc
Original Assignee
Poniard Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poniard Pharmaceuticals Inc filed Critical Poniard Pharmaceuticals Inc
Publication of CN104288119A publication Critical patent/CN104288119A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201410283507.2A 2007-02-09 2008-02-08 稳定化的吡铂口服剂型 Pending CN104288119A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88917107P 2007-02-09 2007-02-09
US60/889,171 2007-02-09
US88968107P 2007-02-13 2007-02-13
US60/889,681 2007-02-13

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880011357A Division CN101678046A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Publications (1)

Publication Number Publication Date
CN104288119A true CN104288119A (zh) 2015-01-21

Family

ID=39682046

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201410283507.2A Pending CN104288119A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型
CN200880011357A Pending CN101678046A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200880011357A Pending CN101678046A (zh) 2007-02-09 2008-02-08 稳定化的吡铂口服剂型

Country Status (12)

Country Link
EP (1) EP2114418A4 (https=)
JP (1) JP2010518089A (https=)
KR (1) KR20090109129A (https=)
CN (2) CN104288119A (https=)
AU (1) AU2008214202A1 (https=)
BR (1) BRPI0806418A2 (https=)
CA (1) CA2677640A1 (https=)
HK (1) HK1206267A1 (https=)
IL (1) IL200262A0 (https=)
MX (1) MX2009008488A (https=)
RU (1) RU2009133446A (https=)
WO (1) WO2008097661A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107778331A (zh) * 2016-08-27 2018-03-09 鲁南制药集团股份有限公司 一种甲啶铂的提纯方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
WO2010120336A1 (en) * 2009-04-15 2010-10-21 Poniard Pharmaceuticals, Inc. High bioavailability oral picoplatin anti-cancer therapy
EP3145931B1 (en) * 2014-05-23 2021-03-31 Mingsight Pharmaceuticals, Inc. Treatment of autoimmune disease
CN108864177B (zh) * 2018-04-20 2020-07-28 公安部物证鉴定中心 [2h3]-1-甲氨基-2-苯基丙烷的合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665771A (en) * 1995-02-14 1997-09-09 Johnson Matthey Public Limited Company Platinum complexes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0204139A3 (en) * 2000-02-16 2003-07-28 Yamanouchi Pharma Co Ltd Use of n-[6-methoxi-5-(2-methoxiphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]-2phenyl-etienesulfonamide for producing pharmaceutical composition using for reducing pain in an endothelin-induced disease
JP2004529929A (ja) * 2001-04-23 2004-09-30 ニュクリスト ファーマシューティカルズ コーポレーション アポトーシスの誘導およびマトリックスメタロプロテイナーゼの阻害のための金属の使用
DE10141528B4 (de) * 2001-08-24 2006-08-10 Faustus Forschungs Cie. Translational Cancer Research Gmbh Platin(II)- und Platin(IV)-Komplexe und ihre Verwendung
US20050119238A1 (en) * 2002-03-01 2005-06-02 Baron John A. Compositions and methods for preventing sporadic neoplasia in colon
AU2003251955A1 (en) * 2002-07-16 2004-02-02 Sonus Pharmaceuticals, Inc. Platinum compound
EP1545459A4 (en) * 2002-08-02 2007-08-22 Transave Inc PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME
CA2559722A1 (en) * 2004-03-18 2005-09-29 Transave, Inc. Administration of cisplatin by inhalation
US20060205810A1 (en) * 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665771A (en) * 1995-02-14 1997-09-09 Johnson Matthey Public Limited Company Platinum complexes

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107778331A (zh) * 2016-08-27 2018-03-09 鲁南制药集团股份有限公司 一种甲啶铂的提纯方法
CN107778331B (zh) * 2016-08-27 2020-06-30 鲁南制药集团股份有限公司 一种甲啶铂的提纯方法

Also Published As

Publication number Publication date
WO2008097661A1 (en) 2008-08-14
EP2114418A1 (en) 2009-11-11
MX2009008488A (es) 2010-01-15
IL200262A0 (en) 2010-04-29
KR20090109129A (ko) 2009-10-19
CN101678046A (zh) 2010-03-24
RU2009133446A (ru) 2011-03-20
JP2010518089A (ja) 2010-05-27
EP2114418A4 (en) 2013-01-09
BRPI0806418A2 (pt) 2011-09-06
AU2008214202A1 (en) 2008-08-14
HK1206267A1 (en) 2016-01-08
CA2677640A1 (en) 2008-08-14

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