CN104271596B - 肽激素的降钙素cgrp家族的肽拮抗剂和它们的用途 - Google Patents

肽激素的降钙素cgrp家族的肽拮抗剂和它们的用途 Download PDF

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CN104271596B
CN104271596B CN201380010942.1A CN201380010942A CN104271596B CN 104271596 B CN104271596 B CN 104271596B CN 201380010942 A CN201380010942 A CN 201380010942A CN 104271596 B CN104271596 B CN 104271596B
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CN104271596A (zh
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克里斯托弗·J·索尔斯
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/225—Calcitonin gene related peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/22—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of calcitonin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201380010942.1A 2012-01-26 2013-01-25 肽激素的降钙素cgrp家族的肽拮抗剂和它们的用途 Expired - Fee Related CN104271596B (zh)

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CN201810931542.9A CN108997490A (zh) 2012-01-26 2013-01-25 肽激素的降钙素cgrp家族的肽拮抗剂和它们的用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261591236P 2012-01-26 2012-01-26
US61/591,236 2012-01-26
PCT/US2013/023260 WO2013112912A1 (en) 2012-01-26 2013-01-25 Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use

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CN104271596A CN104271596A (zh) 2015-01-07
CN104271596B true CN104271596B (zh) 2018-09-18

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CN201810931542.9A Pending CN108997490A (zh) 2012-01-26 2013-01-25 肽激素的降钙素cgrp家族的肽拮抗剂和它们的用途

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US (3) US9193776B2 (https=)
EP (2) EP2807187B1 (https=)
JP (3) JP6025871B2 (https=)
KR (2) KR101855242B1 (https=)
CN (2) CN104271596B (https=)
AU (2) AU2013211929B2 (https=)
CA (1) CA2861392C (https=)
DK (1) DK2807187T3 (https=)
ES (2) ES2641325T3 (https=)
IL (2) IL233655A (https=)
MX (1) MX347229B (https=)
NO (1) NO2864579T3 (https=)
RU (2) RU2624016C2 (https=)
WO (1) WO2013112912A1 (https=)

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KR101855242B1 (ko) * 2012-01-26 2018-05-09 크리스토퍼 제이. 소레스 펩타이드 호르몬의 칼시토닌 cgrp 패밀리의 펩타이드 길항제 및 그의 용도
EP3027644B1 (en) * 2013-07-30 2019-08-21 Christopher J. Soares Cgrp agonist peptides
JO3669B1 (ar) 2015-01-06 2020-08-27 Ferring Bv بيبتيدات مضَادَّة لببتيد المرتبط بجين الكالسيتونين
EP3400237A4 (en) * 2016-01-04 2020-03-04 Adepthera LLC Peptide analogs
CA3035561A1 (en) 2016-09-02 2018-03-08 Christopher J. Soares Use of cgrp receptor antagonists in neuroprotection and neurological disorders
CA2967616A1 (en) * 2016-09-19 2018-03-19 The Governors Of The University Of Alberta Brain penetrant amylin receptor based peptides for alzheimer's disease
US20200353088A1 (en) * 2017-11-06 2020-11-12 Auckland Uniservices Limited Peptide conjugate cgrp receptor antagonists and methods of preparation and uses thereof
JP7214100B2 (ja) * 2019-01-18 2023-01-30 株式会社大一商会 遊技機
JP7214104B2 (ja) * 2019-01-18 2023-01-30 株式会社大一商会 遊技機
JP7214102B2 (ja) * 2019-01-18 2023-01-30 株式会社大一商会 遊技機
CN116456981A (zh) * 2020-11-19 2023-07-18 辉瑞爱尔兰制药公司 用于改善的grp抑制剂递送的组合物

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Also Published As

Publication number Publication date
AU2013211929A1 (en) 2014-09-11
KR101855242B1 (ko) 2018-05-09
EP3272769A1 (en) 2018-01-24
HK1249915A1 (en) 2018-11-16
MX2014008960A (es) 2015-01-16
IL233655A (en) 2017-06-29
IL233655A0 (en) 2014-08-31
AU2016205801A1 (en) 2016-08-04
US9193776B2 (en) 2015-11-24
CN108997490A (zh) 2018-12-14
BR112014018284A2 (pt) 2017-07-04
RU2017119773A (ru) 2018-12-06
RU2014131605A (ru) 2016-03-20
JP2017036308A (ja) 2017-02-16
US10370425B2 (en) 2019-08-06
CA2861392C (en) 2021-08-17
KR20140132342A (ko) 2014-11-17
EP3272769B1 (en) 2020-06-17
DK2807187T3 (en) 2017-09-11
NO2864579T3 (https=) 2018-01-20
RU2017119773A3 (https=) 2020-11-18
CA2861392A1 (en) 2013-08-01
JP6025871B2 (ja) 2016-11-16
KR20170071613A (ko) 2017-06-23
US20170204155A1 (en) 2017-07-20
HK1201068A1 (en) 2015-08-21
JP6411425B2 (ja) 2018-10-24
KR102052983B1 (ko) 2019-12-06
AU2013211929B2 (en) 2016-05-26
MX347229B (es) 2017-04-19
RU2742826C2 (ru) 2021-02-11
RU2624016C2 (ru) 2017-06-30
JP2015513318A (ja) 2015-05-07
IL252555B (en) 2020-06-30
EP2807187A1 (en) 2014-12-03
ES2641325T3 (es) 2017-11-08
EP2807187B1 (en) 2017-07-26
US20140329752A1 (en) 2014-11-06
IL252555A0 (en) 2017-07-31
ES2819825T3 (es) 2021-04-19
CN104271596A (zh) 2015-01-07
US20160145315A1 (en) 2016-05-26
JP2019006821A (ja) 2019-01-17
WO2013112912A1 (en) 2013-08-01

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