CN104257804B

CN104257804B - Precious jade medicine preparation for the treatment of AIDS and preparation method thereof

Info

Publication number: CN104257804B
Application number: CN201410483435.6A
Authority: CN
Inventors: 梁琼平; 庞赵生; 黄金官
Original assignee: JINXIU YAO AUTONOMOUS COUNTY YAO MEDICAL HOSPITAL
Current assignee: JINXIU YAO AUTONOMOUS COUNTY YAO MEDICAL HOSPITAL
Priority date: 2014-09-22
Filing date: 2014-09-22
Publication date: 2016-05-11
Anticipated expiration: 2034-09-22
Also published as: CN104257804A

Abstract

The invention discloses precious jade medicine preparation for the treatment of AIDS and preparation method thereof, be made up of oral preparations and washout preparation, described oral preparations comprises: the dandelion 10-30 part of coming into leaves; Sophora flower 10-30 part; Radix Glycyrrhizae 10-30 part; Silvernine 10-30 part; Keel wind 10-30 part; Do not go out woods 10-30 part; Blank sheet of paper fan 10-30 part; Giant knotweed 10-30 part, externally used compound raw material and weight fraction thereof comprise: snake is 20-40 part only; Evodia lepta 20-40 part; Kuh-seng 20-40 part; Repent jussiaea herb 20-40 part; Nine li of bright 20-40 parts; Bayberry bark 20-40 part; Ninebark 20-40 part; Silvernine 20-40 part; Phellodendron bark 20-40 part; Chinese sumac 20-40 part. It is according to " the Treating AIDS with Traditional Chinese Medicine clinical technology scheme (trying) " of the tcm clinical practice feature of Guangxi AIDS and State Administration of Traditional Chinese Medicine's formulation, in conjunction with factors such as the climate characteristic in Guangxi, environmental factor, staff condition, constitutive characters, prepare a kind of medicine that adapts to the most of infection populations in Guangxi, can give patient's mitigation symptoms, suppress AIDS virus diffusion, improve immunity and be free from side effects.

Description

Precious jade medicine preparation for the treatment of AIDS and preparation method thereof

Technical field

The invention discloses a kind of medicine for the treatment of AIDS and preparation method thereof, specifically taking precious jade medicine as raw materialYao medicinal composition formula and relevant preparation method thereof.

Background technology

AIDS is the great infectious disease of a kind of harmfulness, is caused by aids infection virus (HIV virus). HIV is onePlant the virus that can attack human immune system. It is using most important T lymphocyte in human immune system as main attack orderMark, this cell of considerable damage, makes human body lose immunologic function, and therefore, human body is easy to infect various diseases, and can occur pernicious swollenKnurl, case fatality rate is higher. The incubation period average out to 8～9 year of HIV in human body, suffers from before AIDS, can be without any symptom groundLive and work for many years.

After HIV infects, any clinical manifestation of Nian Kewu more than the several years to 10 starting most. Once develop into AIDS, patientJust can there are various clinical manifestations. The symptom at general initial stage is as common cold, influenza sample, can have that whole body fatigue is unable, foodWant to go down, heating etc., along with increasing the weight of of the state of an illness, symptom increasing day by day, infects as coccus appears reading in vain in skin, mucous membrane, occurs singlePure bleb, herpes zoster, purple plague purpura, blood blister, extravasated blood spot etc.; Gradually invade internal organs later, occur agnogenic continuationHeating, is 3～4 months; Also can occur that cough, shortness of breath, expiratory dyspnea, continuation are suffered from diarrhoea, had blood in stool, hepatosplenomegaly, concurrentMalignant tumour etc. Clinical symptoms are complicated and changeable, all occur but each patient is not above-mentioned all symptoms. Invading lung goes out oftenNow expiratory dyspnea, pectoralgia, cough etc.; Invade stomach and intestine and can cause that continuation suffers from diarrhoea, suffers from abdominal pain, becomes thin unable etc.; Also can invade nerveSystem and cardiovascular system.

If things go on like this, AIDS patient's body and mind will suffer huge torment, although there is no at present effective healing way,Be that speed this respect is set about from slowing down that sb.'s illness took a turn for the worse, providing can be to patient's mitigation symptoms, suppresses AIDS virus diffusion, improvesImmunity and the pure Chinese medicine preparation of being free from side effects are also to bring a kind of Gospel to patient.

Summary of the invention

The object of this invention is to provide the treatment AIDS taking pure precious jade medicine as main active ingredient precious jade medicine preparation andPreparation method.

To achieve these goals, preparation method of the present invention is:

The precious jade medicine preparation for the treatment of AIDS, is made up of oral preparations and washout preparation, and described oral preparations is by weighing belowThe raw material of amount umber is made:

The dandelion 10-30 part of coming into leaves;

Sophora flower 10-30 part;

Radix Glycyrrhizae 10-30 part;

Silvernine 10-30 part;

Keel wind 10-30 part;

Do not go out woods 10-30 part;

Blank sheet of paper fan 10-30 part;

Giant knotweed 10-30 part.

Described washout preparation is made up of the raw material of following parts by weight:

Snake is 20-40 part only;

Evodia lepta 20-40 part;

Kuh-seng 20-40 part;

Repent jussiaea herb 20-40 part;

Nine li of bright 20-40 parts;

Bayberry bark 20-40 part;

Ninebark 20-40 part;

Silvernine 20-40 part;

Phellodendron bark 20-40 part;

Chinese sumac 20-40 part;

Its preparation is oral preparations and washout preparation;

Described oral preparations comprises oral liquid, granule, capsule, tablet and tea in bag;

Described washout preparation comprises bagged product, aqua, effervescent tablet, granule and pulvis.

Described oral preparations preparation technology comprises the steps:

1, oral liquid: get in proportion the above-mentioned dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, do not go out woods, blank sheet of paper fan,Giant knotweed eight tastes, add 10 times of water and add hot reflux decoction two to three times, and each 1 hour, filter, filtrate merges, and gets sucrose and makes in right amountSyrup, merges with above-mentioned liquid, adds anticorrisive agent appropriate, leaves standstill, and filters, filling, obtains oral liquid. Using method: every day 3Inferior, each 5 grams, 30 days courses for the treatment of.

2, granule, capsule or tablet: get in proportion the above-mentioned dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, noGo out woods, blank sheet of paper fan, giant knotweed eight tastes, add 10 times of water and add hot reflux decoction two to three times, each 1 hour, filter, filtrate merges,60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperatureLeave standstill 12 hours, filter, reclaim ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix,Granulation agent, encapsulated, or make tablet. Using method: every day 3 times, each 2-3 gram. 30 days courses for the treatment of.

3, tea in bag: get in proportion the above-mentioned dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, do not go out woods, blank sheet of paper fan,Giant knotweed eight tastes, dry after cleaning respectively, pulverize with pulverizer, cross 50 mesh sieves, in proportion each crushed material are merged, and pack into ventilativeIn Fibre Bag, weight per package 2-5 gram, makes tea in bag. Using method: every day 3 times, each 5 grams, each 10 grams of severe one, 30 daysOne course for the treatment of.

Described washout preparation process thereof comprises the steps:

1, bagged product: get in proportion above-mentioned snake only, bright, the bayberry bark of evodia lepta, kuh-seng, repent jussiaea herb, nine li, nine layersThe clean medicinal material of skin, silvernine, phellodendron bark, Chinese sumac, chopping or pulverize, make powder, sterilization post-drying, by formula rate by each powderMince and mix, pack in the Fibre Bag or paper bag or non-woven bag of water-permeable and air permeable, obtain bagged product. Using method,Before bathing, bagged product water is boiled and is put in pottery or canister, being diluted to required bathing temperature with cold water can steepWash, it is 0.2-0.5 kilogram that every 10 kg of water add the weight of medicine.

2, aqua: get in proportion above-mentioned snake only, bright, the bayberry bark of evodia lepta, kuh-seng, repent jussiaea herb, nine li, ninebark, silverThe clean medicinal material of rattan, phellodendron bark, Chinese sumac, adds 10 times of water and adds hot reflux decoction two to three times, and each 1 hour, filter, filtrate is closedAnd, leave standstill, filter, concentrated refining, batching, filling and sealing, sterilization, packaging, obtains aqua. Using method, bathing is front by aquaBe put in pottery or canister, after then adding boiling water to mix, then be diluted with water to required bathing temperature and get final product foam washing, every 10Kilogram adding the weight of medicine is 300-600 milliliter.

3, effervescent tablet: get in proportion above-mentioned snake only, bright, the bayberry bark of evodia lepta, kuh-seng, repent jussiaea herb, nine li, ninebark,The clean medicinal material of clean medicinal material of silvernine, phellodendron bark, Chinese sumac, adds 10 times of water and adds hot reflux decoction two to three times, and each 1 hour, filter,Filtrate merges, and 60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, add 95% ethanol make containing alcohol amount be60%, room temperature leaves standstill 12 hours, filters, and filtrate recycling ethanol, is concentrated into the thick paste that relative density is 1.32-1.35, adds suitableAmount auxiliary material and appropriate effervescent agent mixing granulation, always mixed, compressing tablet is made effervescent tablet. Using method, before bathing adds out effervescent tabletAfter water-soluble solution, be diluted with water to required bathing temperature and get final product foam washing, it is 8-12 gram that every 10 kg of water add the weight of medicine.

4, granule or pulvis: get in proportion above-mentioned snake only, evodia lepta, kuh-seng, repent jussiaea herb, nine li of bright, bayberry barks, nineThe clean medicinal material of layer skin, silvernine, phellodendron bark, Chinese sumac, adds 10 times of water and adds hot reflux decoction two to three times, and each 1 hour, filter,Filtrate merges, and 60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, add 95% ethanol make containing alcohol amount be60%, room temperature leaves standstill 12 hours, filters, and reclaims ethanol, is concentrated into the thick paste that relative density is 1.32-1.35, adds auxiliary in right amountMaterial, mixes granulation agent or pulvis. Using method, is put into granule or pulvis in pottery or canister before bathing, soAfter add after dissolved in boiled water, be diluted with water to required bathing temperature and get final product foam washing, it is 20-that every 10 kg of water add the weight of medicine60 grams.

Medically research shows that the selected classical precious jade medical instrument of the present invention has following effect:

The above-described dandelion that comes into leaves [Latin formal name used at school] Brassicajuncea (L.) Czern.etcoss, precious jade language is learnedName: get Lie Bie, another name SEMEN SINAPIS ALBAE, is the mature seed of crucifer leaf mustard, this product is less, diameter 0.1～0.2cm. TableFace yellow is to brown color, and minority is rufous. After fragmentation, add water-soaked, the pungent special foul smell splitting occurs. All produce all over China.Conventionally gather when fruit maturation in late summer, get seed, dry. Taste warm in nature is pungent, Gui Jing: enter lung channel (internal organs ownership: return in lung channelMedicine). Function cures mainly: warming lung and reducing phlegm, relieving cough and asthma, and dispersing swelling and dissipating binds, moistening lung slit phlegm, swelling and pain relieving.

Above-described sophora flower is dried floral and the flower of legume Chinese scholartree [Latin formal name used at school] SophorajaponicaL.Flower bud. Precious jade language formal name used at school: by Chinese scholartree. [nature and flavor] hardship, is slightly cold. [return through] returns liver, large intestine channel. [function cures mainly] cooling blood and hemostasis, clearing liver is rushed downFire. Be used for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, spits blood, bleeding from five sense organs or subcutaneous tissue, the hot hot eyes of liver, has a headache dizzy. 1. " Japan hanako materia medica ": " control fiveHemorrhoid, pained, eye is red, kills abdomen and hides worm and heat, controls skin wind, and intestines diarrhea due to wind-evil blood, dysentery. " 2. " medicine origin ": " cool large intestineHeat. " 3. " detailed outline ": " fries fragrant frequently chewing, and controls aphonia and larynx numbness. Treat and spit blood again, nosebleed, metrorrhagia and metrostaxis. " 4. " book on Chinese herbal medicine is just ": " cool large intestine,Kill infantile malnutrition due to digestive disturbances or intestinalparasites worm. Control skin sore, the erosion of vulva is wet itches, and anal fistula is separated red bayberry and disliked sore, chancre volt poison. It is contrary that " 5. " medical center bun is wanted ": " lets out lung, rushes downInternal heat, clearing away the liver-fire, hard kidney water. " 6. " book on Chinese herbal medicine is looked for the truth ": " controls large and small having blood in stool, tongue nosebleed. " 7. " it is former that book on Chinese herbal medicine is asked ": " is cool blood key medicine.Control gastral cavilty soldier pain, kill roundworm. The retinitis of " 8. " northeast medicine is planted will ": " treatment diabetes. "

Above-described Radix Glycyrrhizae [Latin formal name used at school] GlycyrrhizauralensisFisch. Precious jade language formal name used at school: port Chu. [propertyTaste] sweet, flat. [return through] thoughts of returning home, lung, spleen, stomach warp. [function cures mainly] invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergencyPain relieving, coordinating the drug actions of a prescription. For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, the anxious pain of four limbs contraction, carbuncle is swollenSore, cushion toxicity, strong.

Above-described silvernine [Latin formal name used at school] LonicerrajaponicaThunb. Precious jade language formal name used at school: bear other dragon. NotName: honeysuckle, Caulis Lonicerae, honeysuckle, two look flower rattans, two precious rattans, right-hand rotation rattan, sub-wind rattan, mandarin duck rattan, two flowers. Silvernine is praised from ancient timesFor clearing heat and detoxicating good medicine. The sweet cold air fragrance of its property, clear heat with drugs of sweet flavour and cold nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil. Silvernine can be declaredLoose wind-heat, also kind removing summer-heat blood poison, for various febrile diseases, as diseases such as body heat, dermexanthesis, a spot, hot carbuncle carbuncle, abscesss of throat, allEffect is remarkable. Silvernine is just extensive and famous with its medical value since ancient times. Its effect is mainly clearing heat and detoxicating, cures mainly warm diseaseHeating, toxic-heat and blood stasis, ulcer serious case of furuncle etc. Modern study proves, silvernine contains the pharmacologically active such as chlorogenic acid, cyanidenon glycosidesPoint, the various pathogens such as hemolytic streptococcus, Staphylococcus aureus and infection of the upper respiratory tract Causative virus etc. are had to stronger pressing downPower processed, also can strengthen in addition immunity, anti-early pregnancy, protects liver, antitumor, anti-inflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorptionCholesterol etc., its clinical application is very extensive, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute uropoiesis with other medicines compatibilitySystem infection, hypertension etc. more than 40 are planted illness.

Silvernine is cold in nature, and taste is sweet, enters lung, the heart, stomach warp, has clearing heat and detoxicating, anti-inflammatory, qi-restoratives and treat effect of wind, cures mainly turgorLower disease, warm disease heating, the diseases such as hot malicious large carbuncle and tumour. Its for dizzy dizzy, dry do thirsty, hidrosis is unhappy, enteritis, bacillary dysentery,Measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, changeThe illnesss such as purulence tonsillitis all have certain curative effect.

Above-described keel wind [Latin formal name used at school] Alsophilaspinulosa (Wall.exHook.) R.M.Tryon,Precious jade language formal name used at school: delay and exempt from. For the stem of Cyatheaceae plant spinulose tree fern. [nature and flavor] micro-hardship; Flat. [return through] kidney; Stomach; Lung channel. [function masterControl] dispel rheumatism; Promoting blood circulation and removing obstruction in channels; Relieving cough and asthma; Clearing heat and detoxicating; Desinsection. Main air pain of dampness syndrome; Lumbago due to the kidney deficiency; Traumatic injury; LittleIntestines gas pain; Acute toothache; Cough; Asthma; Mange; Roundworm disease; Enterobiasis and flu-prevention.

Above-describedly do not go out woods [Latin formal name used at school] Ardisiajaponica(Thunb) Blume, precious jade language formal name used at school: must robHug. Another name: the Japanese ardisia, little green grass or young crops, short tea, short pin three youths, sunshade lid pearl, Herba Ardisiae Japonicae tea, always not large, be Myrsinacea, ZijinBos undershrub or semishrub plant, function cures mainly: relieving cough and reducing sputum, the removing toxic substances of dispeling the wind, promoting blood circulation and stopping pain. For bronchitis, great YeProperty pneumonia, infantile pneumonia, pulmonary tuberculosis, hepatitis, dysentery, acute nephritis, urinary tract infections, stimulates the menstrual flow, traumatic injury, rheumatalgia;Skin itching is controlled in external application, dermatitis rhus. Anti-HIV effect: acquired immunodeficiency disease (AIDS) spreads soon, clinical symptoms complexity, deathRate is high, and within 1981, finding this disease, be subject to national governments always and pay attention to, and to its pathogen-HIV(HIV) carried out large quantity research. Gondola Piacente, anti-acquired the exempting from of screening from medicinal plant in 1996 such as SoniaThe damaged syndrome research work of epidemic disease can not find that the methanolic extract of woods aerial part has shown the external HIV-resistant activity of appropriateness.

Above-described blank sheet of paper fan [Latin formal name used at school] MussaendaphilippicaRichard, precious jade language formal name used at school: prick border,Another name: snow calyx flower, Guangdong Radix Mussaendae, Radix Mussaendae, butterfly rattan, the sweet tea in mountain, celestial sweet rattan. [nature and flavor] hardship; Micro-sweet; Cool. [meritCan cure mainly] clearing heat and detoxicating; Relieving summer-heat dampness removing. Main flu; Heat-hyperpyrexia; Abscess of throat; Dysentery; Have loose bowels; Difficult urination; Unknown swollenPoison; Venomous snake bite.

Above-described giant knotweed [Latin formal name used at school] ReynoutriajaponicaHoutt, have another name called acid cylinder bar, acid bucket reed,Large osteosynthesis, spot village root. Precious jade language formal name used at school: red woods. Nature and flavor: micro-hardship, is slightly cold. Gui Jing: return liver, courage, lung channel. Function cures mainly: dispels the wind, and profitWet, the broken stasis of blood, stimulates the menstrual flow. Control rheumatism arthralgia and myalgia, jaundice with damp-heat pathogen, under stranguria with turbid discharge band, women is through closing, lochiostasis, a lump in the abdomen causing distension and pain,Blood under anal fistula. Injury from falling down, scalds, and dislikes sore tinea disease. Anti-arrhythmia and anti-cardiac muscle lose blood, promoting blood circulation and removing blood stasis.

1. " not Lu ": the main tonneau moon water, the broken mass formed by blood stasis knot that stays.

2. Tao Hongjing: main sudden and violent lump in the abdomen, wine stain takes it.

3. " property of medicine opinion ": control large heat irritated, quench the thirst, diuresis, presses all heat poison.

4. supplement to the Herbal: main air is between joint and blood stasis. Liquor takes it as wine.

5. " Japan hanako materia medica ": after managing property extravesated blood not under, trusted subordinate's turgor. Apocenosis, main sore furuncle carbuncle poison, married woman's bruise, flutters damageHemostasis, broken wind poison knot gas.

6. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": attack all pyogenic infections, only have sore throat, diuresis, walks channels and collaterals. Control five pouring gonorrhoeas, anal fistula, sore carbuncle,Married woman's leukorrhea with reddish discharge.

7. " medical center bun is wanted ": hard kidney, strong Yang yi Jing, strengthens the bone, and increases strength. Apply to get injured by a fall and lose place, can reunion of fractured tendons and bones.

8. " south of the Five Ridges gather medicinal herbs record ": treating snakebite, impetigo, stops loss the pain of injury.

9. " Guizhou side's medicine among the people collection ": astringing to arrest bleeding, control hemorrhoid complicated by anal fistula, curing rheumatism, delivers loose trembling with fear, loose hemostasis, burn is controlled in external application.

10. " experiment of TCM research ": control excess fire toothache, the wet rotten leg of sore, toe discrimination is wet rotten.

Above-described snake is [Latin formal name used at school] Polygonunperfoliatuml only, the white grass in [another name] river, Herba Lespedezae Cuneatae,Pears head thorn, polygonum perfoliatum, precious jade language formal name used at school: thousand hug. [nature and flavor] cold nature, taste acid. [function cures mainly] inducing diuresis for removing edema, clearing heat and detoxicating,Cough-relieving. Be used for nephritic dropsy, pertussis, rush down dysentery, eczema, furuncle, venomous snake bite.

Above-described evodia lepta [Latin formal name used at school] Evodialepta (Spreng.) Merr, [another name] three fork hardships, littleYellow loose, Ji Gushu, three bifurcation hardships, three rifles, trident tiger, precious jade language formal name used at school: make up the difference bright. [chemical analysis] leaf is containing volatile oil, main in oilWanting composition is australene, alditol. The aobvious alkaloid reaction of root. [pharmacological action] bacteriostatic test: this product has and presses down shigella flexneriMake and use. [nature and flavor] hardship, cold. [function cures mainly] is clearing heat and detoxicating, blood stasis removing analgesic. Prevent and treat influenza, popular myelencephalonFilm inflammation, encephalitis B, heatstroke, the high heat that cures cold, tonsillitis, sphagitis, lung abscess, pneumonia, malaria, rheumatic arthritis,Sciatica, pain in waist and lower extremities, stomachache, icteric hepatitis, gelsemium elegan (elegant jessamine) is poisoning. Osteopatia sprain is controlled in external application, worm snake bite, carbuncleFuruncle poison, trauma infection contamination, eczema, dermatitis.

Above-described kuh-seng [Latin formal name used at school] Sophoraflavescens, [another name] wild Chinese scholartree, Hao Hanzhi, matrine,Bone, Chinese scholartree, Albizzia kalkora, precious jade language formal name used at school: because of bright. [nature and flavor] hardship, cold. [return through] thoughts of returning home, liver, stomach, large intestine, urinary bladder channel. [functionCure mainly] heat-clearing and damp-drying drug, desinsection, diuresis. For hot dysentery, have blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore,Pruitus, mange leprosy; Control trichomonas vaginitis outward.

Above-described repent jussiaea herb [Latin formal name used at school] JussiaearepensL., [another name] water cover dish, collapses grass (" swardThe property of medicine is standby to be wanted "), water jar dish (" it is former that book on Chinese herbal medicine is asked "), the fire hose (" Liu Gang miscellanies "), Entada phaseoloides (" Tian Bao book on Chinese herbal medicine "), water leaf mustard (" ridgeThe south record of gathering medicinal herbs "), Shui Caiyue (" Fujian traditional herbal medicine "), dog intestines grass (" conventional glossary of Herbs and Drugs among the people "), crosses river rattan (" Traditional Chinese Medicine in SichuanWill "), loquat dish, air bladder grass (Guangzhou army " conventional Chinese herbal medicine handbook "), false water spinach (" Guangxi Chinese herbal medicine "), water floats rattan (" good fortuneBuild Chinese herbal medicine "). Precious jade language formal name used at school: post and understand crotch. [nature and flavor] are " the sward property of medicine is standby to be wanted " 1.: " lightly seasoned, cold in nature. " 2. " Fujian grass among the peopleMedicine ": " sweet, cold, nontoxic. " [function cures mainly] heat-clearing, diuresis, detumescence, removing toxic substances. Control cough caused by dryness-heat, wine subcutaneous ulcer, gonorrhoea, measles, pelletPoison, the carbuncle furunculosis that swells. 1. " the sward property of medicine is standby to be wanted ": " reason wine disease, applies carbuncle on the back, treating snakebite, top dog bite, diuresis, smashes juice drink. " 2." Tian Bao book on Chinese herbal medicine ": " dampness removing heat, row water channel, controls arthralgia and myalgia. " 3. " Fujian traditional herbal medicine ": " diuresis is antipyretic. Reason wine subcutaneous ulcer, controls snakeWound. " 4. " Luchuan book on Chinese herbal medicine ": " is clearing heat and detoxicating, inducing diuresis for removing edema. Control epidemic blisters, blood scabies. " 5. " Traditional Chinese Medicine in Sichuan will ": " controls various soresAnd gonorrhoea. "

Above-described nine li of bright [Latin formal name used at school] SenecioscandensBuch.-Ham.exDoDn, [another name] thousandIn and, climbing groundsel, nine neck light, eliminate completely. Precious jade language formal name used at school: seek thunder ginger. [nature and flavor] hardship, pungent, cool. Slightly poisonous. [function cures mainly]Clearing heat and detoxicating, cool blood detumescence, clears liver and improve vision. For wind fire cute conjunctivitis, sore furuncle poison, the illnesss such as skin eczema and dysentery stomachache.

Above-described bayberry bark [Latin formal name used at school] Myricarubra (Lour.) S.etZua., [nature and flavor] hardship; Pungent; Micro-Puckery; Warm in nature; Precious jade language formal name used at school: red bayberry hole. [return through] liver; Stomach warp, [function cures mainly] promoting flow of qi and blood circulation; Pain relieving; Hemostasis; Removing toxic substances disappearsSwollen. Main epigastric pain; Hypochondriac pain; Toothache; Hernia; Traumatic injury; Fracture; Spit blood; Bleeding from five sense organs or subcutaneous tissue; Hemorrhoid blood; Uterine bleeding; Traumatism and bleeding; SoreSwell and ache; Mumps; Noma; The burning hot wound of soup; Ulcer on the shank; Eczema; Mange; Flu; Have loose bowels; Dysentery.

Above-described ninebark [Latin formal name used at school] llexrotundaThunb., [another name] iron holly bark, silver bark,White orchid perfume (or spice), bear gall wood. Precious jade language formal name used at school: exempt from hole, stockaded village. [nature and flavor] hardship, cool. [function cures mainly] is clearing heat and detoxicating, swelling and pain relieving. Be used forFlu, tonsillitis, abscess of throat, acute gastroenteritis, treating rheumatic ostealgia; Traumatic injury is controlled in external application, carbuncle furuncle sore, and traumatism and bleeding,Burn and scald.

Above-described phellodendron bark [Latin formal name used at school] CortexPhellodendriChinensis, [another name] cork tree, unitCypress, bark of a cork tree wood. Precious jade language formal name used at school: Wang Pei hole. This product is rutaceae wampee PhellodendronchinenseSchneid.Or the dry bark of cork tree PhellodendronamurenseRupr.. The former practises title " CORTEX PHELLODENDRI CHINENSE ", and the latter practises title " closes yellowCypress ". Strip after bark, remove tertia, dry. [nature and flavor] hardship, cold. [return through] returns kidney, urinary bladder channel. [function cures mainly] heat-clearingEliminating dampness, purging intense heat is except steaming, detoxification sore treatment. For damp-heat dysentery, jaundice, under band, heat is drenched, beriberi, and impotence { is warded off }, hectic fever due to yin labor heat, night sweat,Seminal emission, sore swollen toxin, eczema itch. Stir-baked CORTEX PHELLODENDRI with salt solution is nourishing Yin and falling fire. For fire excess from yin deficiency, night sweat hectic fever due to yin.

Above-described Chinese sumac [Latin formal name used at school] RhuschinensisMill, [another name] salt efflorescence cypress, salt sourwood, depositedYan Shu, Pu Lian salt, husband carry on a shoulder pole salt, Chinese gall tree. Precious jade language formal name used at school: Pi Liang. [nature and flavor] acid, salty, cold. [function cures mainly] heat-clearing solutionPoison, loose stasis of blood hemostasis. Root: cold, fever, bronchitis, cough spitting of blood, enteritis, dysentery, hemorrhoid hemorrhage; Root, leaf external application are controlled to fall and are beatenDamage, venomous snake bite, dermatitis rhus.

In the present invention, the pharmacological function of each composition is:

The dandelion that comes into leaves is controlled in cold drink and contains, and cough phlegm is stagnant, and chest diaphragm is full vexed.

Sophora flower cooling blood and hemostasis, clearing liver-fire.

Radix Glycyrrhizae is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.

Silvernine dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile diseases.

Keel wind is dispelled rheumatism; Promoting blood circulation and removing obstruction in channels; Relieving cough and asthma; Clearing heat and detoxicating.

Do not go out woods relieving cough and reducing sputum, the removing toxic substances of dispeling the wind, promoting blood circulation and stopping pain, has anti-HIV effect.

Blank sheet of paper fan is clearing heat and detoxicating; Relieving summer-heat dampness removing.

Giant knotweed dispels the wind, dampness removing, the broken stasis of blood.

Snake is inducing diuresis for removing edema only, clearing heat and detoxicating, cough-relieving.

Evodia lepta is clearing heat and detoxicating, blood stasis removing analgesic. Inhibiting bacteria and diminishing inflammation.

Kuh-seng heat-clearing and damp-drying drug, desinsection, diuresis.

Repent jussiaea herb heat-clearing, diuresis, detumescence, removing toxic substances.

Nine li bright clearing heat and detoxicating, and cool blood detumescence, clears liver and improve vision.

The bayberry bark promoting flow of qi and blood circulation; Pain relieving; Hemostasis; Removing toxicity for detumescence.

Ninebark is clearing heat and detoxicating, swelling and pain relieving.

Phellodendron bark heat-clearing and damp-drying drug, purging intense heat is except steaming, detoxification sore treatment.

Chinese sumac is clearing heat and detoxicating, loose stasis of blood hemostasis.

Be exactly more than that the present invention treats precious jade medicine preparation of AIDS and preparation method thereof, production process flow process is simple, raw materialSource is wide, uses simple. The function that integrates its medicine is dispel the wind removing toxic substances, promoting blood circulation and stopping pain, inhibiting bacteria and diminishing inflammation, inducing diuresis to reduce edema, solutionPoison is treated acting on of sore.

The mechanism that precious jade medicine preparation of the present invention can be treated AIDS be precious jade medicine can detoxification sore treatment, inducing diuresis for removing edema, alleviationPatient's symptom (as case 1).

Washout precious jade medicine is accelerated sweat gland secretion, accelerates toxin metabolism, sweating and expelling toxin; All right activation cycle, improves blood micro-Circulation, Lymph microcirculation, meridian qi and blood circulation, thus immunity strengthened. For oral administration can conditioning viscera, clearing heat and detoxicating, for oral administration outsideBetter by both partner treatment effects.

The present invention is the formula that gives the Yao nationality in area in boudoir, Guangxi, In Southwest China raising immunity function among the peopleScreening forms. The ground such as the Yao nationality in Guangxi is distributed in Jin Xiu, respectful city, all pacifies, Fu Chuan, the mountain area of inhabitation is with green hills and clear waters, animals and plants moneySource is abundant, and the compatriot of the Yao nationality, owing to there is no doctor trained in Western medicine, by traditional precious jade medicine treatment disease, has treated a lot of difficult and complicated cases, wound for a long timeHaving made brilliant precious jade medical science and said, is the rarity of nationality of China, nowadays, also having carried out many explorations aspect treatment AIDS, relies onThe treatment of precious jade doctor precious jade medicine has obtained new achievement.

Beneficial effect of the present invention:

1, the medicine that the present invention has immunity function by Yao nationality's ancient prescription does not go out refining the forming such as woods, utilizes Chinese herbal medicine selfEffect reaches the object for the treatment of AIDS, has no side effect, without worrying chemical residual.

2, production process is simple, does not pollute; Using method is simple, can be made into multiple formulation, is applicable to different needs of patients;Raw material source is wide, cheap, alleviates patient economy burden.

Detailed description of the invention

Embodiment 1,

Oral liquid: get by weight proportion 10 parts of the dandelions that come into leaves, 10 parts, sophora flower, 10 parts, Radix Glycyrrhizae, 10 parts of silvernines, keel wind 10Part, do not go out 10 parts, 10 parts of woodss, blank sheet of paper fan, 10 parts of giant knotweeds, add 10 times of water and add hot reflux and decoct two to three times, each 1 hour, filterCross, filtrate merges, and gets sucrose and makes in right amount syrup, merges with above-mentioned liquid, adds anticorrisive agent appropriate, leaves standstill, and filters, filling,Obtain oral liquid. Using method: every day 3 times, each 5 grams, 30 days courses for the treatment of.

Embodiment 2,

Granule, capsule or tablet: get by weight proportion 20 parts of the dandelions that come into leaves, 20 parts, sophora flower, 20 parts, Radix Glycyrrhizae, silvernine20 parts, 20 parts of keel wind, do not go out 20 parts of woodss, 20 parts, blank sheet of paper fan, 20 parts of giant knotweeds, add 10 times of water and add hot reflux and decoct two to three times,Each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, addsIt is 60% that 90% ethanol makes containing alcohol amount, and room temperature leaves standstill 12 hours, filters, and reclaims ethanol, and being concentrated into relative density is 1.30-1.35Thick paste, add appropriate amount of auxiliary materials, mix granulation agent or encapsulated, or make tablet. Using method: every day 3 times, everyInferior 3 grams. 30 days courses for the treatment of.

Embodiment 3,

Tea in bag: get by weight proportion 30 parts of the dandelions that come into leaves, 30 parts, sophora flower, 30 parts, Radix Glycyrrhizae, 30 parts of silvernines, keel wind 30Part, do not go out 30 parts, 30 parts of woodss, blank sheet of paper fan, 30 parts of giant knotweeds, after cleaning respectively, dry, pulverize with pulverizer, cross 50 mesh sieves, in proportionEach crushed material is merged, pack in ventilative Fibre Bag, 5 grams of weight per packages, make tea in bag. Using method: every day 3 times, everyInferior 5 grams, each 10 grams of severe one, 30 days courses for the treatment of.

Embodiment 4,

Bagged product: it is bright to get by weight proportion 20 parts of only 20 parts of snakes, 20 parts of evodia leptas, 20 parts of kuh-sengs, repent jussiaea herb, nine li20 parts, the clean medicinal material of 20 parts of bayberry barks, 20 parts of ninebarks, 20 parts of silvernines, 20 parts of phellodendron barks, 20 parts of Chinese sumacs, chopping or pulverize,Make powder, sterilization post-drying, mixes each crushed material by formula rate, packs Fibre Bag or paper bag of water-permeable and air permeable intoOr in non-woven bag, obtain bagged product. Using method, boils bagged product water to be put into pottery or canister before bathingIn, being diluted to required bathing temperature with cold water and getting final product foam washing, it is 0.2-0.5 kilogram that every 10 kg of water add the weight of medicine.

Embodiment 5,

Aqua: get by weight proportion only 28 parts of snakes, 28 parts of evodia leptas, 28 parts of kuh-sengs, 28 parts, nine li bright 28 of repent jussiaea herbsThe clean medicinal material of part, 28 parts of bayberry barks, 28 parts of ninebarks, 28 parts of silvernines, 28 parts of phellodendron barks, 28 parts of Chinese sumacs, adds 10 times of water heatingReflux and decoct two to three times, each 1 hour, filter, filtrate merges, and leaves standstill, and filters, and concentrated refining, batching, filling and sealing, killsBacterium, packaging, obtains aqua. Using method, is put into aqua in pottery or canister before bathing, then adds boiling water to mixAfter, then be diluted with water to required bathing temperature and get final product foam washing, every 10 kilograms to add the weight of medicine be 600 milliliters.

Embodiment 6,

Effervescent tablet: get by weight proportion only 35 parts of snakes, 35 parts of evodia leptas, 35 parts of kuh-sengs, 35 parts, nine li bright 35 of repent jussiaea herbsThe clean medicinal material of clean medicinal material of part, 35 parts of bayberry barks, 35 parts of ninebarks, 35 parts of silvernines, 35 parts of phellodendron barks, 35 parts of Chinese sumacs, adds 10 timesWater adds hot reflux and decocts two to three times, and each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to 55 ° of C relative densitiesFor the clear cream of 1.15-1.20, add 95% ethanol make containing alcohol amount be 60%, room temperature leave standstill 12 hours, filter, filtrate recycling ethanol, denseBe reduced to the thick paste that relative density is 1.32-1.35, add appropriate amount of auxiliary materials and appropriate effervescent agent mixing granulation, always mixed, compressing tablet is madeEffervescent tablet. Using method, adds effervescent tablet after dissolved in boiled water before bathing, and be diluted with water to required bathing temperature and get final product foam washing,It is 10 grams that every 10 kg of water add the weight of medicine.

Embodiment 7,

Granule or pulvis: get by weight proportion 40 parts of only 40 parts of snakes, 40 parts of evodia leptas, 40 parts of kuh-sengs, repent jussiaea herb, nineIn bright 40 parts, the clean medicinal material of 40 parts of bayberry barks, 40 parts of ninebarks, 40 parts of silvernines, 40 parts of phellodendron barks, 40 parts of Chinese sumacs, add 10 timesWater adds hot reflux and decocts two to three times, and each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to 55 ° of C relative densitiesFor the clear cream of 1.15-1.20, add 95% ethanol make containing alcohol amount be 60%, room temperature leave standstill 12 hours, filter, reclaim ethanol, be concentrated intoRelative density is the thick paste of 1.32-1.35, adds appropriate amount of auxiliary materials, mixes granulation agent or pulvis. Using method, before bathingGranule or pulvis are put in pottery or canister, then add after dissolved in boiled water, be diluted with water to required bathing temperatureGet final product foam washing, it is 60 grams that every 10 kg of water add the weight of medicine.

Clinical observation:

1. this compound treatment AIDS clinical symptoms, sign situation of change (table 1):

Tcm clinical practice symptom, sign situation of change before and after this compound treatment of table 1

Model case:

Case 1:

The infected Ma, peasant, there is bubble rash during in 2007, the primary dcreening operation HIV positive, makes a definite diagnosis HIV sense by confirmatory testDye. Surveyed at that time CD₄Cell count is 549, and body weight is 61kg, starts to occur poor appetite, indigestion, spirit in December, 2008Dispirited, become thin, weak, spontaneous perspiration, pharyngalgia, arthralgia, easy catching a cold, on average monthly 1 time, diarrhoea, average every day 5 times, watery stool,Time have chilly, sour regurgitation, deeptensepulse is unable, pale tongue with white fur takes antidiarrheal agent certainly, has no improvement, then to our hospital, survey CD₄CytometerNumber is 351, and body weight is 50kg, and the traditional Chinese medical science is examined as having loose bowels, and syndrome of yang deficiency of spleen and kidney gives this prescription and adds Psoralea corylifolia 20g, nutmeg 15g, native FuSiberian cocklebur 20, dogwood fruit 20g coordinates this prescription washout precious jade medicine washout whole body to treat altogether after 2 months simultaneously, and patient's appetite is greatly improved,Spirit takes a turn for the better, and only, symptom of diarrhea is clearly better spontaneous perspiration, and defecate 2 average every day, embarks on journey, and body weight 52kg, takes a good rest,Adhere to suitable exercise. Follow up a case by regular visits to in September, 2012, patient catches a cold 4 times every year on average, occasionally has diarrhoea, surveys CD₄Cell count is 482.

Case 2

The infected Chen, civilian worker, the primary dcreening operation HIV positive in the time that the end of the year 2007, Yin Gaore was in hospital, by Guangxi, dragon's pool hospital is trueConfirmation is tested and is diagnosed as HIV infection. Surveyed at that time CD₄Cell count is to start to occur becoming thin in January, 559,2011, and pharyngalgia is weak, stealsSweat, headache, easy catching a cold, on average monthly 1 time, clear abundant urine, impotence, premature ejaculation, can not normally carry out sexual life, time have a chilly, timeThere is sour regurgitation, hydroptysis, slow and sunken pulse is unable, and pale tongue with white fur takes Western medicine certainly, has no improvement, then to our hospital, surveys CD₄CytometerNumber is 302, and the traditional Chinese medical science is examined as impotence, and syndrome of yang deficiency of spleen and kidney gives this prescription and adds monkshood 10g, semen allii tuberosi 15g, rhizoma zingiberis 20g, actinolite15g, barrenwort 15g, sealwort 10g, cultivated land 10g gives this washout prescription medicine washout whole body simultaneously, coordinates doctor trained in Western medicine HAART treatment, controlsDuring treatment, have no obvious toxic-side effects, treat altogether after 5 months, patient's appetite is greatly improved, and spirit takes a turn for the better, and night sweat stops, impotenceShape is clearly better, can normally have sexual intercourse, and looks steadily it and adheres to taking antiviral drugs, takes a good rest, and adheres to suitable exercise. Follow up a case by regular visits toExtremely, in June, 2011, patient catches a cold, and surveys CD₄Cell count is 405.

Clinical conclusion:

Chinese medicine preparation of the present invention shows in clinical effectiveness, and the Chinese medicine preparation that the present invention treats AIDS to symptom and sign allImprove significantly, wherein, diarrhoea, weak, headache be improved, in sum, the Chinese medicine for the treatment of AIDS of the present inventionPreparation has the effect that improves AIDS related complex shape sign.

Claims

Treatment AIDS precious jade medicine preparation, it is characterized in that: formed by oral preparations and washout preparation, this oral preparations by withThe Chinese medicine material of lower parts by weight is made:

The dandelion 10-30 part of coming into leaves;

Sophora flower 10-30 part;

Radix Glycyrrhizae 10-30 part;

Silvernine 10-30 part;

Keel wind 10-30 part;

Do not go out woods 10-30 part;

Blank sheet of paper fan 10-30 part;

Giant knotweed 10-30 part;

Described washout preparation is made up of the raw material of following parts by weight:

Snake is 20-40 part only;

Evodia lepta 20-40 part;

Kuh-seng 20-40 part;

Repent jussiaea herb 20-40 part;

Nine li of bright 20-40 parts;

Bayberry bark 20-40 part;

Ninebark 20-40 part;

Silvernine 20-40 part;

Phellodendron bark 20-40 part;

Chinese sumac 20-40 part;

Its preparation is oral preparations and washout preparation;

Described oral preparations comprises oral liquid, granule, capsule, tablet and tea in bag;

Described washout preparation comprises effervescent tablet, granule and pulvis.
2. the precious jade medicine preparation for the treatment of AIDS according to claim 1, is characterized in that: described oral liquorComprise the steps:

By weight ratio get the dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, do not go out woods, blank sheet of paper fan, giant knotweed eight tastes,Add 10 times of water and add hot reflux decoction two to three times, each 1 hour, filter, filtrate merges, and gets sucrose and makes in right amount syrup, with upperState liquid and merge, add anticorrisive agent appropriate, leave standstill, filter, filling, make oral liquid.
3. the precious jade medicine preparation for the treatment of AIDS according to claim 1, is characterized in that: described granule, capsule orMethod for preparing tablet thereof comprises the steps:

By weight ratio get the dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, do not go out woods, blank sheet of paper fan, giant knotweed eight tastes,Add 10 times of water and add hot reflux decoction two to three times, each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to 55 ° of C phasesThe clear cream that is 1.15-1.20 to density, add 90% ethanol make containing alcohol amount be 60%, room temperature leave standstill 12 hours, filter, reclaim ethanol,Be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulation agent or encapsulated, or doBecome tablet.
4. the precious jade medicine preparation for the treatment of AIDS according to claim 1, is characterized in that: described preparation method of teabagComprise the steps:

By weight ratio get the dandelion that comes into leaves, sophora flower, Radix Glycyrrhizae, silvernine, keel wind, do not go out woods, blank sheet of paper fan, giant knotweed eight tastes,After cleaning respectively, dry, pulverize with pulverizer, cross 50 mesh sieves, in proportion each crushed material is merged, pack in ventilative Fibre Bag,Weight per package 2-5 gram, makes tea in bag.
5. the precious jade medicine preparation for the treatment of AIDS according to claim 1, is characterized in that: the effervescent tablet product of washout preparationPreparation technology comprise the steps: by weight ratio get snake only, evodia lepta, kuh-seng, repent jussiaea herb, nine li of bright, red bayberriesThe clean medicinal material of skin, ninebark, silvernine, phellodendron bark, Chinese sumac, adds 10 times of water and adds hot reflux decoction two to three times, and each 1 hour,Filter, filtrate merges, and 60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, adds 95% ethanol and makes to containAlcohol amount is 60%, and room temperature leaves standstill 12 hours, filters, and filtrate recycling ethanol, is concentrated into the thick paste that relative density is 1.32-1.35,Add appropriate amount of auxiliary materials and appropriate effervescent agent mixing granulation, compressing tablet is made effervescent tablet.
6. the precious jade medicine preparation for the treatment of AIDS according to claim 1, is characterized in that: the granule of washout preparation or powderThe preparation technology of agent product comprise the steps: by weight ratio get snake only, evodia lepta, kuh-seng, repent jussiaea herb, nine liThe clean medicinal material of bright, bayberry bark, ninebark, silvernine, phellodendron bark, Chinese sumac, adds 10 times of water and adds hot reflux and decoct two to three times, each1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to the clear cream that 55 ° of C relative densities are 1.15-1.20, adds 95% secondIt is 60% that alcohol makes containing alcohol amount, and room temperature leaves standstill 12 hours, filters, and reclaims ethanol, and being concentrated into relative density is the thick of 1.32-1.35Cream, adds appropriate amount of auxiliary materials, mixes granulation agent or pulvis.