CN104225108B - Treat the Chinese medicine preparation and preparation method of nocturnal fretfulness in infants - Google Patents
Treat the Chinese medicine preparation and preparation method of nocturnal fretfulness in infants Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation for treating nocturnal fretfulness in infants, the primary raw material of following weight proportions is taken to be prepared：Rush（It is dry）25 45 parts；12 18 parts of hempleaf groundsel herb；8 12 parts of the membrane of a chicken's gizzard；69 parts of the root bark of Chinese wolf-berry；36 parts of wilsonii.This Chinese medicine preparation is made fully according to the characteristics of traditional Chinese medical science principle and nocturnal fretfulness in infants, has good therapeutic action, treatment nocturnal fretfulness in infants effect is good, and quick, clinical test confirms that the Chinese medicine preparation has good therapeutic effect to nocturnal fretfulness in infants.
Description
Technical field
The present invention relates to traditional Chinese medicine field, more particularly, to a kind of Chinese medicine preparation and preparation method for treating nocturnal fretfulness in infants.
Background technology
Nocturnal fretfulness in infants refers to that children are as usual daytime, at nightfall then frequent crying egersis.After suffering from this disease, the duration counts at least
Day, at most through the moon.Show as：Children are more to cry incessantly at night, and daytime is normal.Or a burst of crying, or the open clouds until dawn, after crying still
It can fall asleep；Or with seeing flushed face and red lips, or paroxysm stomachache, or abdominal distension vomiting, or when terrified, hoarseness etc..General persistence,
A few days at least, at most through the moon, cross then from only.This disease is more common in the infant within half years old.Crying is that a kind of instinct of baby is anti-
Should, because not having ability of language expression still in cradle, " crying " is exactly a kind of mode of expression requirement or pain.As it is hungry,
Thirsty, clothing supercooling or overheat, wet diaper, the erosion of buttocks armpit skin, eczema are had an itch, or the reason such as insect bite, or form love
The custom embraced, can cause infant to be cry and screamed, and this cry and scream is normal instinct reflection.Some diseases, as rickets, parasitosis,
Surgical disease etc. can also cause baby crying.
The traditional Chinese medical science think nocturnal fretfulness in infants often because of malaria, the heart is warm, is fallen ill frightened, dyspepsia.(1) deficiency-cold in spleen and stomach, symptoms include children face
Color is bluish white, and four limbs owe temperature, and happiness lies prostrate, and belly is sent out cool, and leg of bending over to curl up is cry and screamed, and do not feel like eating, big loose stool is thin, clear abundant urine.Pale tongue
Tongue is white, thready and moderate pulse, light red superficial venule of the index finger.Control suitable warming middle-JIAO and strengthening the spleen.(2) heart heat is frightened, symptoms include children's flushed face and red lips, haves the fidgets, mouth and nose
Outlet heat, uneasy sleeping at night, one frightened one first, and body abdomen all warms up, constipation, scanty drak urine.Red tip of tongue, yellow tongue fur, slippery and rapid pulse.Control preferably clear
Heat is calmed the nerves.(3) frightened fear, symptoms include night cry, and flushing or general green grass or young crops, have no peace of mind, unease due to fright, easily wake up in sleeping, are crowed in dream
Cry, sound is miserable and tight, in frightened shape, tightly snuggles up to female bosom, the change how without exception of pulse condition words.Control suitable tranquillizing the mind by relieving convulsion.(4) infantile dyspeptic gastroenteropathy,
Symptoms include night crys, apocleisis tells breast, rotten pantothenic acid, turgor of suffering from abdominal pain, restless and sleepless, sour smelly, thick greasy fur of defecating, and fingerprint purple is stagnant.
Crying and screaming for baby is divided into " physiological " and " pathologic " two major class.Physiological is cry and screamed：It is hungry, mouth is drunk is baby cried
Most common reason in noisy, was more common within 3 months, and this is due to that breast milk is insufficient, milk-powder brewing is excessively dilute, and upper one because some
Reason is not had enough.Environment temperature is too high, perspiration is more, and baby cries and screams incessantly because thirsty.It is hot and cold, wet, itch, pain environment temperature
Supercooling or overheat can cause the discomfort of baby, but overheat is easier to cause uneasiness of crying and screaming than supercooling.Diaper wet (stool, urine) is not
Change, represented in the form of crying and screaming to father and mother in time.Baby is because of eczema, hidrosis, itch caused by the unclean grade of skin or because of pinworm
Worm, which climbs to perianal to cause, very to itch and cries and screams.Just urine feels trained baby, can be required assistance in the form of crying and screaming mother and
When help him to carry out excrement and urine.Baby within living irregular 6 months usually " day and night overturns ", sleeps daytime, cries at night, is commonly called as this
A little babies are " morbid night crying of babies youth ".Pathologic is cry and screamed：Canker sore is often cry and screamed in sucking or feed.Stomachache such as entembole (performance
Cry and screamed for paroxysmal is violent, while pale complexion, vomiting, discharge Currant jelly), acute appendicitis (cry and scream, send out by continuation
Heat, aggravation of being cry and screamed after appendicular perforation), (stomachache is violent, and infant is often stroked at incarceration with hand, occurs for strangulated indirect inguinal hernia
Vomiting), enterospasm (a burst of is cry and screamed, after quiet a period of time cry and screamed again because of enterospasm) etc. again.Head caused by many reasons
Pain can all make baby cry, such as generate heat, and be cried in a shrill voice in a burst of during meningitis.When Ipsilateral when otitis externa, furuncle are breast-feeded
When ear presses close to mother's body or cry and scream more severe when pulling Ipsilateral ear.The vagitus difference that " pathologic " cries and screams is sought
Often, scream sometimes, hoarseness, normal sudden play is cried；It is One's spirits are drooping with adstante febre, pale complexion, sometimes with vomiting, abdomen
Rush down, stool has blood, and hospital need to be gone to further to ascertain the reason.
In the method for existing Chinese medicine nocturnal fretfulness in infants, publication number CN103638436A（Application number
201310661758.5）Patent document disclose a kind of medicine for treating nocturnal fretfulness in infants and preparation method thereof, it is by following
Bulk drug in weight range is made：3-9 grams of yncaria stem with hooks, 5-15 grams of wheat, 25-35 grams of the fruit of Cherokee rose, 5-15 grams of cicada slough, spina date seed
10-20 grams, 10-20 grams of amber, 15-25 grams of betel nut, 5-15 grams of rush, 10-20 grams of perilla leaf, raw 10-20 grams of dens draconis, honey
5-15 grams, 10-20 grams of lophatherum gracile, 5-15 grams of humus flava usta, 10-20 grams of earthworm, 10-20 grams of fructus amomi, 5-15 grams of lily, Chinese cassia tree 5-15
Gram, 25-35 grams of galangal, 3-9 grams of oyster, 3-9 grams of the root of three-nerved spicebush, 10-20 grams of Asiatic plantain, 3-9 grams of Gorgon fruit, 5-15 grams of pears, polygala 25-
35 grams, 25-35 grams of courage star, 10-20 grams of French beans, 10-20 grams of rhizoma cyperi, 5-15 grams of radix bupleuri, 6-12 grams of the seed of Oriental arborvitae, grass-leaved sweetflag 25-35
Gram.Publication number CN103830554A（Application number 201410082407.3）Patent document disclose a kind of nocturnal fretfulness in infants for the treatment of
Chinese medicine composition and preparation method thereof, it is made up of the bulk drug of following parts by weight：Cicada slough 4-6 parts, polygala 4-6 parts, tuber of dwarf lilyturf 4-6
Part, yncaria stem with hooks 4-6 parts, radix glehniae 2-4 parts, Chinese yam 2-4 parts, peppermint 2-4 parts, spina date seed 2-4 parts, rush 1-2 parts, fushen 1-2
Part, radix glycyrrhizae 1-2 parts.Publication number CN101912548A（Application number 201010264856.1）Patent document disclose a kind for the treatment of
Medicine of nocturnal fretfulness in infants and preparation method thereof, mainly it is made from the following raw materials in parts by weight：Rose 1-20 parts, bitter orange flower 1-
20 parts, coptis 1-20 parts, shell of seaear 1-20 parts, yncaria stem with hooks 1-20 parts, leaf of bamboo 1-20 parts, rush 1-20 parts, Poria 1-20 parts,
Vine of multiflower knotweed 1-20 parts, honey-fried licorice root 1-20 parts, calcined Dragon's bone 1-20 parts, calcined oyster shell 1-20 parts, dried rhizome of rehmannia 1-20 parts, jujube kernel 1-20 parts, contain
Measure edible ethanol 1-20 parts for more than 95%.
In a word, traditional Chinese medicine achieves certain effect in terms of nocturnal fretfulness in infants is treated, but there is also some problems：Clinically
It is preferable not enough to the therapeutic effect of nocturnal fretfulness in infants, need further to be improved.
The content of the invention
In view of the shortcomings of the prior art, prepared it is an object of the invention to provide one kind simple, convenient to take, portable
The Chinese medicine preparation and preparation method of nocturnal fretfulness in infants are treated, the curative effect of medicine is definite and without any side effects.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
The Chinese medicine preparation of nocturnal fretfulness in infants is treated, takes the primary raw material of following weight proportions to be prepared：Rush（It is dry）25-
45 parts；Hempleaf groundsel herb 12-18 parts；The membrane of a chicken's gizzard 8-12 parts；Root bark of Chinese wolf-berry 6-9 parts；Wilsonii 3-6 parts.
The Chinese medicine preparation of nocturnal fretfulness in infants is treated, preferable scheme is that the primary raw material for taking following weight proportions is prepared：
Rush（It is dry）30-40 parts；Hempleaf groundsel herb 14-16 parts；The membrane of a chicken's gizzard 9-11 parts；Root bark of Chinese wolf-berry 7-8 parts；Wilsonii 4-5 parts.
The Chinese medicine preparation of nocturnal fretfulness in infants is treated, more preferred scheme is prepared by the primary raw material for taking following weight proportions
Form：Rush（It is dry）35 parts；15 parts of hempleaf groundsel herb；10 parts of the membrane of a chicken's gizzard；7.5 parts of the root bark of Chinese wolf-berry；4.5 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, step are as follows：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heating 10-20 minutes, take out, cool, weed out rice, grind, cross 140-160 mesh sieves, powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 80-120 mesh sieves is crossed, soaks, be placed in distiller, be passed through
Steam distillation, volatile oil is together distilled with water, collect distillate, cooling, divide and take oil reservoir, oil reservoir is heated to 100 DEG C,
4-8min is sterilized, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled 20-40 minutes every time, filter twice
Liquid merges, and adds rock sugar, adds step（2）The volatile oil of gained, it is 1.20-1.40 to be concentrated into relative density, adds step（1）
Gained powder, it is well mixed, sterile packaged.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（1）Moderate heat heats
13-17 minutes（Preferably, moderate heat heats 15 minutes）.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（1）Cross 146-156
Mesh sieve（Preferably, 150 mesh sieves are crossed）.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（2）The dosage of water is
3-5 times of medicinal powder quality（Preferably, the dosage of water is 4 times of medicinal powder quality）.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（2）Sterilize 5-7min
（Preferably, 6min is sterilized）.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（3）Rock sugar dosage is
The 10%-20% of filtrate quality（Preferably, rock sugar dosage is the 15% of filtrate quality）.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants, preferable scheme are：Step（3）It is concentrated into relative
Density is 1.25-1.35（Preferably, relative density is concentrated into as 1.30）.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
The pharmacology of main Chinese medicine material is as follows used in the present invention：
Rush：It is sweet, light, it is slightly cold.The thoughts of returning home, lung, small intestine, bladder warp.Nickname rush, Lin's grass, Chinese alpine rush, wild seat
Grass, horse palm fibre root, wild horse palm fibre.For the stem marrow or herb of rush family plant rush.With promoting diuresis for stranguria, the work(of clearing heart fire
Effect.For gonorrhoea, oedema, hematuria, the puckery pain of oliguria, jaundice with damp-heat pathogen, dysphoria and insomnia, nocturnal fretfulness in infants, larynx numbness, aphthae, wound.
Hempleaf groundsel herb：Acrid flavour, sweet, slightly warm in nature.The thoughts of returning home, lung two pass through.With heat-clearing eliminating the phlegm, the effect of antitussive and antiasthmatic.For lung
Interior infection, chronic bronchitis, asthmatic bronchitis, ARI etc..
The membrane of a chicken's gizzard：It is sweet, it is mild-natured.Returns spleen, stomach, small intestine, bladder warp.For the drying inner wall of sandbag of Phasianidae animal family chicken.Tool
There is the effect of stomach strengthening and digestion promoting, arresting seminal emission.For dyspepsia, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
The root bark of Chinese wolf-berry：It is sweet, it is cold in nature.Return lung, liver and kidney channel.For the dry root skin of matrimony vine of solanaceae plant or lycium barbarum.Have
Cool blood is except steaming, the effect of clearing lung-heat fall fire.For deficiency of Yin hectic fever, hectic fever due to yin night sweat, cough with lung heat, spitting of blood, bleeding from five sense organs or subcutaneous tissue, Heat Diabetes.
Wilsonii：Acrid flavour, slight bitter, it is warm-natured.Returns spleen, kidney, the heart channel of Hang-Shaoyin.Drying root and rhizome for Araliaceae wilsonii or
Stem.With replenishing qi to invigorate the spleen, the effect of tonifying the kidney to relieve mental strain.It is physically weak weak for the insufficiency of both the spleen and the kindey, poor appetite, soreness of waist and knee joint, have a sleepless night more
Dream.
Principle of the medicament of the present invention based on Chinese traditional treatment nocturnal fretfulness in infants, it is that have studied lot of documents, pharmacology work and facing
Made of on the basis of bed experiment.This medicament selected materials are traditional Chinese medicine, without any side effects.This medicament is pressed completely
It is made according to the characteristics of traditional Chinese medicine principle and nocturnal fretfulness in infants, can be very good to treat nocturnal fretfulness in infants, therapeutic effect effect is good, takes effect
It hurry up, there is good therapeutic effect to nocturnal fretfulness in infants.
Brief description of the drawings
Fig. 1 is the alleviation situation of nocturnal fretfulness in infants symptom after the Chinese medicine preparation using the gained treatment nocturnal fretfulness in infants of embodiment 5；
Fig. 2 is mental status situation after the Chinese medicine preparation using the gained treatment nocturnal fretfulness in infants of embodiment 5.
Embodiment
Technical scheme, but protection domain not limited to this are described in detail with reference to embodiment and experimental example.
Embodiment 1 treats the Chinese medicine preparation of nocturnal fretfulness in infants, takes the primary raw material of following weight proportions to be prepared（Every part
Take 20g）：Rush（It is dry）25 parts；12 parts of hempleaf groundsel herb；8 parts of the membrane of a chicken's gizzard；6 parts of the root bark of Chinese wolf-berry；3 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants is：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heats 10 minutes, takes out, cools, weed out rice, grinds, and crosses 140 mesh sieves, and powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 80 mesh sieves is crossed, soaks, be placed in distiller, be passed through vapor
Distillation, makes volatile oil together be distilled with water, collects distillate, cooling, divides and take oil reservoir, and oil reservoir is heated to 100 DEG C, sterilization
4min, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled every time 20 minutes, filtrate conjunction twice
And rock sugar is added, add step（2）The volatile oil of gained, it is 1.20 to be concentrated into relative density, adds step（1）Gained powder,
It is well mixed, sterile packaged.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
Xue XX of model case one, man, 9 months, Ganzhou City of Jiangxi Province people from Xingguo County.It is born so far, frequent night sleep two
After three hours, cry and scream, the state that shows that I have a dream and yet, not a dream, behavior is fierce, irritated.When crying and screaming, there is speech, but father and mother communicate
It is invalid, still cry and scream, with pacifying, embracing, the way such as fooling, make a noise fiercer on the contrary, performance is more irritated, and action increases.Time
Continue 20 minutes or so, fallen asleep after crying and screaming stable, average every night all can be once.Without other illnesss of such as suffering from abdominal pain.Once
Took " "Xingpi Yanger Granule" "（Major function：The traditional Chinese medical science：Appetizing of being amusing, nourishing blood and tranquilization, intestine-stabling and anti-diarrheal.For caused by Spleen-Qi Deficiency
Children anorexia, suffer from diarrhoea loose stool, irritated night sweat, the enuresis morbid night crying of babies.）；Make amends for one's faults calcium and zinc.But effect is bad, its father and mother is very
It is anxious.
Later, its mother had heard the effect of the Chinese medicine preparation for the treatment of nocturnal fretfulness in infants of the invention very in a mother rolls into a ball
It is good, wherein after just having the Chinese medicine preparation that several mothers take the treatment nocturnal fretfulness in infants to dotey, cure the morbid night crying of babies disease of dotey.
Then the father and mother of Xue doteys determine to try, and take the Chinese medicine preparation for the treatment of nocturnal fretfulness in infants of the gained of embodiment 1 after 2 days, at night
The number cry and screamed just considerably reduces, and sees this curative effect, and endlessly, it is really very to feel this medicine to its father and mother's happiness！This is also added very
Big confidence, then adhere to taking the Chinese medicine preparation of the treatment nocturnal fretfulness in infants of the gained of embodiment 1, to nocturnal fretfulness in infants at the 6th day
Symptom also disappears substantially, simply occurs situation about crying and screaming at night once in a while, and can also be fallen asleep again quickly after slightly pacifying.
Embodiment 2 treats the Chinese medicine preparation of nocturnal fretfulness in infants, takes the primary raw material of following weight proportions to be prepared（Every part
Take 10g）：Rush（It is dry）45 parts；18 parts of hempleaf groundsel herb；12 parts of the membrane of a chicken's gizzard；9 parts of the root bark of Chinese wolf-berry；6 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants is：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heats 20 minutes, takes out, cools, weed out rice, grinds, and crosses 160 mesh sieves, and powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 120 mesh sieves is crossed, soaks, be placed in distiller, is passed through water steaming
Steam distillation, volatile oil is together distilled with water, collect distillate, cooling, divide and take oil reservoir, oil reservoir is heated to 100 DEG C, sterilization
8min, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled every time 40 minutes, filtrate conjunction twice
And rock sugar is added, add step（2）The volatile oil of gained, it is 1.40 to be concentrated into relative density, adds step（1）Gained powder,
It is well mixed, sterile packaged.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
Two weeks XX of model case, female, 10 months, Jinan City, Shandong Province people from Licheng District.Height 71CM, 9 kilograms of body weight.From
It is born till now to only have and 1 fever must be crossed during 5 wheat harvesting period, throat has inflammation.Sleep is all pretty good always after birth, basic at night
It oneself can fall asleep, recently on the occasion of giving child's weaning stage, show as tossing about in bed before wean, it is independent to change lectulum after wean
Sleep, crying of once waking up in about 2 hours.Especially after midnight.Being fallen asleep at night since these last few days needs adult to have in arms, midnight
Often oneself turn over to get up also not opening eyes and begin to cry, wanting adult to take in one's arms every time could fall asleep to pacify.Sleep in the daytime few, evening
On sleep uneasiness, wake up 1-2 time, sometimes or even can wake up three or four times, 5 points or so of morning just can not again fall asleep per party.Daytime is total
It is to feel sleepy, but the length of one's sleep is short, difficulty falling asleep.
Take the Chinese medicine preparation of the treatment nocturnal fretfulness in infants of the gained of embodiment 22 days, the number that night wakes up significantly reduces, very
To the Chinese medicine preparation for the treatment nocturnal fretfulness in infants for whole night all without waking up, continuing to take the gained of embodiment 2 sometimes to dotey, the
The situation that night wakes up at 5 days is substantially achieved control, and its father and mother is very delight, and dotey can ensure the sleep of abundance, Er Qieqi
Father and mother do not have energy to go to work without the daytime turned from side to side every evening, and life has revert to normal track again.Adhere to continuing
Take and consolidate over 2 days, learn, fully recovered in the follow-up in later stage, do not recur again.
Embodiment 3 treats the Chinese medicine preparation of nocturnal fretfulness in infants, takes the primary raw material of following weight proportions to be prepared（Every part
Take 20g）：Rush（It is dry）30 parts；14 parts of hempleaf groundsel herb；9 parts of the membrane of a chicken's gizzard；7 parts of the root bark of Chinese wolf-berry；4 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants is：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heats 13 minutes, takes out, cools, weed out rice, grinds, and crosses 146 mesh sieves, and powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 90 mesh sieves is crossed, soaks, be placed in distiller, is passed through water steaming
Steam distillation, volatile oil is together distilled with water, collect distillate, cooling, divide and take oil reservoir, oil reservoir is heated to 100 DEG C, sterilization
5min, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled every time 25 minutes, filtrate conjunction twice
And rock sugar is added, add step（2）The volatile oil of gained, it is 1.25 to be concentrated into relative density, adds step（1）Gained powder,
It is well mixed, sterile packaged.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
Embodiment 4 treats the Chinese medicine preparation of nocturnal fretfulness in infants, takes the primary raw material of following weight proportions to be prepared（Every part
Take 15g）：Rush（It is dry）40 parts；16 parts of hempleaf groundsel herb；11 parts of the membrane of a chicken's gizzard；8 parts of the root bark of Chinese wolf-berry；5 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants is：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heats 17 minutes, takes out, cools, weed out rice, grinds, and crosses 156 mesh sieves, and powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 110 mesh sieves is crossed, soaks, be placed in distiller, is passed through water steaming
Steam distillation, volatile oil is together distilled with water, collect distillate, cooling, divide and take oil reservoir, oil reservoir is heated to 100 DEG C, sterilization
7min, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled every time 35 minutes, filtrate conjunction twice
And rock sugar is added, add step（2）The volatile oil of gained, it is 1.35 to be concentrated into relative density, adds step（1）Gained powder,
It is well mixed, sterile packaged.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
The poplar XX of model case three, man, 8 months, people from Juye County of Heze city of Shandong province.Recent months is all to sleep not at night
It is real, probably wake up within every 45 minutes and cry once, family members groans very much.It can also be cried when daytime sleeps, there is very big borborygmus in belly
Sound, the sound of congee is also pitched, stool is very smelly, and child's saliva is a lot, to change 20 pieces or so of saliva cloth daily, sigh, stool
It is smelly, catch a cold the later stage, even cough, also phlegm.Child comes before shop to have seen to hospital, what is it about doctor does not find out.
Later, by making some inquiries about, it is thus understood that the present invention treatment nocturnal fretfulness in infants Chinese medicine preparation the effect of it is fine, then take
After 2 days, just can once it sleep at night two hours, borborygmus sound is obviously reduced.When taking by the 4th day, child's energy night
Sleep normally, and saliva is also less more, daily two blocks of saliva cloth can.Stool is smelly not as in the past.Belly is pitched
Congee sound almost without.Parent is very happy, can sleep finally individual long.
Embodiment 5 treats the Chinese medicine preparation of nocturnal fretfulness in infants, takes the primary raw material of following weight proportions to be prepared（Every part
Take 20g）：Rush（It is dry）35 parts；15 parts of hempleaf groundsel herb；10 parts of the membrane of a chicken's gizzard；7.5 parts of the root bark of Chinese wolf-berry；4.5 parts of wilsonii.
The preparation method of the Chinese medicine preparation of above-mentioned treatment nocturnal fretfulness in infants is：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard,
Gently stir, moderate heat heats 15 minutes, takes out, cools, weed out rice, grinds, and crosses 150 mesh sieves, and powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 100 mesh sieves is crossed, soaks, be placed in distiller, is passed through water steaming
Steam distillation, volatile oil is together distilled with water, collect distillate, cooling, divide and take oil reservoir, oil reservoir is heated to 100 DEG C, sterilization
6min, it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, is decocted twice, is boiled every time 30 minutes, filtrate conjunction twice
And rock sugar is added, add step（2）The volatile oil of gained, it is 1.30 to be concentrated into relative density, adds step（1）Gained powder,
It is well mixed, sterile packaged.
Instructions of taking：Taken with warm water or warm milk, the baby baby of daily 4-6g, 3-6 months of 1-2 months is daily
6-8g, the daily 8-10g of child of more than 7 months, can take several times.
The clinical practice of the Chinese medicine preparation of the gained treatment nocturnal fretfulness in infants of test example embodiment 5：In June, 2008-2010 year 5
Month, screen 250 nocturnal fretfulness in infants patients, wherein girl 131, boy 119 in Duo Suo hospitals.2 weeks before experiment, to the people
Group carries out Continuous Observation, records symptom and change, is randomly divided into experimental group and control group, wherein, experimental group has 150 people, control
Group has 100 people.Experimental group takes the Chinese medicine preparation of the gained treatment nocturnal fretfulness in infants of embodiment 5, is taken with warm water or warm milk, 1-
Baby baby daily 6-8g, the daily 8-10g of child of more than 7 months of daily 4-6g, 3-6 months of 2 months, can be several times
Take.Control group takes other medicines（The conventional medications such as bezoar from monkeys dissipates, nocturnal fretfulness in infants particle）.Curative effect situation criterion：Cure：
After taking 5 days, the symptom of nocturnal fretfulness in infants disappears；It is effective：After taking 5 days, nocturnal fretfulness in infants symptom mitigation；It is invalid：After taking 5 days,
Malaise symptoms are unchanged or recur.
Observation period is limited to 5 days, and observed content is as follows：
1st, 1 day is an observation cycle, records the concrete condition of nocturnal fretfulness in infants, counts each cycle nocturnal fretfulness in infants and obtain
The ratio of alleviation, as a result such as accompanying drawing 1：
Analysis：It is right as can be seen that the effect of the Chinese medicine preparation of the gained treatment nocturnal fretfulness in infants of embodiment 5 is more preferable from accompanying drawing 1
Nocturnal fretfulness in infants has more preferable therapeutic action, more than using other drugs control group the effect of it is good.
2nd, 1 day is an observation cycle, observes and records the mental status of patient, it is good to count each cycle mental status
Good ratio, as a result such as accompanying drawing 2：
Analysis：It can be deduced from accompanying drawing 2, the essence of the patient of the Chinese medicine preparation of the gained treatment nocturnal fretfulness in infants of embodiment 5
The ratio of god in order is substantially higher than control group, can deduce the Chinese medicine using the gained treatment nocturnal fretfulness in infants of embodiment 5
The effect of the effect of experimental group of preparation is more than the control group for using other drugs is good.
3rd, the experimental group of the Chinese medicine preparation of nocturnal fretfulness in infants is treated using the control group of other drugs and using the gained of embodiment 5
The effect of compare, as a result as shown in table 1：
Table 1:Take rear therapeutic effect proving and comparisom
As can be seen from Table 1：The cure rate for taking the experimental group of the Chinese medicine preparation of the gained treatment nocturnal fretfulness in infants of embodiment 5 is high
Up to 82%, and the cure rate for taking the control group of other drugs is only 47%；The effective percentage of experimental group is 98.67%, and inefficiency is only
For 1.33%, and the effective percentage of control group is only 86%, and inefficiency has but been up to 14%.So take the gained of the embodiment of the present invention 5
Treatment nocturnal fretfulness in infants Chinese medicine preparation positive effect be better than take other drugs control group the effect of.
It can be seen that by accompanying drawing 1-2：Take the treatment of the experimental group of the Chinese medicine preparation of the treatment nocturnal fretfulness in infants of the gained of embodiment 5
The effect of effect is more than the control group for taking other drugs is good.Wherein, the 1st day taken, in terms of nocturnal fretfulness in infants remission：Experiment
The alleviation ratio of group is up to 51%, and control group is only 35%；At the 4th day, the alleviation ratio of experimental group has reached 94%, and compares
Group has only reached 75%, and during by the 5th day, the alleviation ratio of experimental group has reached 98%, and control group has also only reached 83%.In essence
In terms of refreshing situation：To take the 1st day, the alleviation ratio of experimental group has just reached 56%, and control group is only 43%, when taking the 4th day,
Experimental group alleviates ratio and has reached 96%, and control group is only 77%, and at the 5th day, the good ratio of the mental status of experimental group
100% has been up to, and control group only reaches 86%.Can draw, the present invention treatment nocturnal fretfulness in infants Chinese medicine preparation the effect of it is more aobvious
Write, be a kind of medicament of more preferable treatment nocturnal fretfulness in infants.
It should be pointed out that embodiment is the more representational example of the present invention, it is clear that skill of the invention
Art scheme is not limited to above-described embodiment, can also there is many variations.One of ordinary skill in the art, it is clearly public with institute of the invention
Written description open or according to file is undoubted to be obtained, and is considered as this patent scope of the claimed.
Claims (10)
1. treat the Chinese medicine preparation of nocturnal fretfulness in infants, it is characterised in that take the raw material of following weight proportions to be prepared：Rush
（It is dry）25-45 parts；Hempleaf groundsel herb 12-18 parts；The membrane of a chicken's gizzard 8-12 parts；Root bark of Chinese wolf-berry 6-9 parts；Wilsonii 3-6 parts.
2. Chinese medicine preparation according to claim 1, it is characterised in that take the raw material of following weight proportions to be prepared：Lamp
Heart grass（It is dry）30-40 parts；Hempleaf groundsel herb 14-16 parts；The membrane of a chicken's gizzard 9-11 parts；Root bark of Chinese wolf-berry 7-8 parts；Wilsonii 4-5 parts.
3. Chinese medicine preparation according to claim 1, it is characterised in that take the raw material of following weight proportions to be prepared：Lamp
Heart grass（It is dry）35 parts；15 parts of hempleaf groundsel herb；10 parts of the membrane of a chicken's gizzard；7.5 parts of the root bark of Chinese wolf-berry；4.5 parts of wilsonii.
4. according to the preparation method of any described Chinese medicine preparations of claim 1-3, it is characterized in that, step is as follows：
（1）Pot is heated, sprinkles the rice soaked, is made on its smooth pot, when moderate heat is heated to meter Mao Yan, adds the membrane of a chicken's gizzard, gently
Stir, moderate heat heating 13-17 minutes, take out, cool, weed out rice, grind, cross 146-156 mesh sieves, powder is stand-by；
（2）Rush and hempleaf groundsel herb are broken into coarse powder, 80-120 mesh sieves is crossed, soaks, the dosage of water is the 3- of medicinal powder quality
5 times, it is placed in distiller, is passed through steam distillation, volatile oil is together distilled with water, collects distillate, cooling, divide and take
Oil reservoir, oil reservoir are heated to 100 DEG C, sterilize 5-7min, and it is standby that air-tight bottle is loaded after cooling；
（3）The root bark of Chinese wolf-berry and wilsonii are placed in marmite, add water, decocts twice, boils 20-40 minutes every time, filtrate is closed twice
And rock sugar is added, rock sugar dosage is the 10%-20% of filtrate quality, adds step（2）The volatile oil of gained, it is concentrated into relatively close
Spend for 1.25-1.35, addition step（1）Gained powder, it is well mixed, sterile packaged.
5. preparation method according to claim 4, it is characterised in that step（1）Moderate heat heats 15 minutes.
6. preparation method according to claim 4, it is characterised in that step（1）Cross 150 mesh sieves.
7. preparation method according to claim 4, it is characterised in that step（2）The dosage of water is 4 times of medicinal powder quality.
8. preparation method according to claim 4, it is characterised in that step（2）Sterilize 6min.
9. preparation method according to claim 4, it is characterised in that step（3）Rock sugar dosage is the 15% of filtrate quality.
10. preparation method according to claim 4, it is characterised in that step（3）Relative density is concentrated into as 1.30.
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