CN105326933A - Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor - Google Patents

Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor Download PDF

Info

Publication number
CN105326933A
CN105326933A CN201510901946.XA CN201510901946A CN105326933A CN 105326933 A CN105326933 A CN 105326933A CN 201510901946 A CN201510901946 A CN 201510901946A CN 105326933 A CN105326933 A CN 105326933A
Authority
CN
China
Prior art keywords
chinese medicine
cure
medicinal plant
plant extraction
insomnia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510901946.XA
Other languages
Chinese (zh)
Inventor
文春光
罗德胜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510901946.XA priority Critical patent/CN105326933A/en
Publication of CN105326933A publication Critical patent/CN105326933A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides traditional Chinese medicine leach liquor for treating insomnia and a preparing method and application of the traditional Chinese medicine leach liquor. The traditional Chinese medicine leach liquor is prepared by steeping a traditional Chinese medicine composition into edible acid-containing liquid, wherein the traditional Chinese medicine composition is prepared from ripe spina date seeds, platycladi seeds, polygala tenuifolia and vine multiflower knotweed. The four kinds of medicine in the traditional Chinese medicine composition supplement one another, together achieve the functions of tranquilizing mind by nourishing the heart, nourishing the stomach, supplementing gallbladder asthenia and resolving in-vivo qi depression, and can effectively relieve and fundamentally remove symptoms such as insomnia. Effective substances steeped out of all the raw materials through acidity can be easily absorbed by the human body. In addition, the traditional Chinese medicine leach liquor is convenient to take and can be taken directly or added with water for brewing drinking.

Description

Medicinal plant extraction of a kind of Cure for insomnia and its preparation method and application
Technical field
The present invention relates to the technical field of pharmaceuticals of Cure for insomnia, particularly relate to medicinal plant extraction of a kind of Cure for insomnia and preparation method thereof.
Background technology
Sleep is that everyone is indispensable.Under the heavy pressure of society, bad, the insomnia of sleeping becomes the ubiquitous problem of people, very naturally will have influence on healthy, daily life and work.The insomnias such as poor sleeping quality, difficulty falling asleep, the shallow easy daydream of sleep and insomnia are the primary sleep problems of the sleep quality of puzzlement modern.In the face of insomnia, some people eats sleeping pill voluntarily, or eats the medicine of Cure for insomnia of commercial type, but more or less all can add the compositions such as sleeping pill in these medicines.Sleeping pill take the natural process that can upset sleep, can not sleeping problems be effected a radical cure, but also the every function of health can be caused to decline, and drug dependence is produced to sleeping pill, once drug withdrawal, even can cause more serious insomnia phenomenon, cure the symptoms, not the disease, lose more than gain.Therefore, need, for causing the root of sleeping to be suited the remedy to the case, to realize the object of effecting a radical cure sleeping problems completely.
Summary of the invention
For above-mentioned defect and the problem of prior art, the object of this invention is to provide medicinal plant extraction of a kind of Cure for insomnia and its preparation method and application.The sleeping problems that poor sleeping quality, difficulty falling asleep, the shallow easy daydream of sleep and insomnia etc. cause can be effected a radical cure.
In order to achieve the above object, the invention provides following technical scheme:
The medicinal plant extraction of a kind of Cure for insomnia of the present invention, is immersed in Chinese medicine composition in edible acidic liquid and prepares; Wherein, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 15 ~ 25 parts, Semen Platycladi 10 ~ 20 parts, 5 ~ 15 parts, Radix Polygalae 5 ~ 15 parts of fleece-flower root rattans.
Further, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 18 ~ 22 parts, Semen Platycladi 12 ~ 18 parts, 8 ~ 12 parts, Radix Polygalae 8 ~ 12 parts of fleece-flower root rattans.
Further, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20 parts, Semen Platycladi 15 parts, 10 parts, Radix Polygalae 10 parts of fleece-flower root rattans.
Each raw material in above-mentioned Chinese medicine composition can be block, also can be Powdered.
Further, the ratio of the quality of described Chinese medicine composition and the volume of edible acidic liquid is 1g ﹕ 25 ~ 50mL.
Preferably, the ratio of the quality of described Chinese medicine composition and the volume of edible acidic liquid is 1g ﹕ 25 ~ 40mL.
Preferably, the ratio of the quality of described Chinese medicine composition and the volume of edible acidic liquid is 1g ﹕ 27 ~ 30mL.
Further, described edible acidic liquid can be vinegar or acid fruit extracting solution.Wherein, peaceful vinegar preferably protected by vinegar.Acid fruit extracting solution can be Fructus Citri Limoniae extract, Fructus Citri junoris extracting solution etc.
The preparation method of the medicinal plant extraction of a kind of Cure for insomnia of the present invention, comprises and above-mentioned Chinese medicine composition is added the step of soaking in edible acidic liquid; Environmental condition during immersion is: under room temperature, ventilation lucifugal and the environment of drying.
Further, soak time is 5 ~ 15 days.
The medicinal plant extraction of Cure for insomnia of the present invention can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types, such as, functional drinks, health food, medicine etc.
The kind of described flavoring agent and consumption are selected according to actual described taste.Particularly, described flavoring agent can be Mel, and the volume ratio of described Mel and edible acidic liquid is 0.3 ~ 1.5 ﹕ 1.Preferably, the volume ratio of described Mel and edible acidic liquid is 0.5 ~ 1 ﹕ 1.
In the Chinese medicine extract of Cure for insomnia of the present invention, directly drink after can adding a small amount of flavoring agent, such as, the volume ratio of the Mel added and edible acidic liquid is 0.3 ~ 0.5 ﹕ 1.Also, after can adding more flavoring agents, Instant Drinks preparation is obtained; Add drinking water time edible to be again diluted to suitable concn and to drink, such as, the volume ratio of the Mel added and edible acidic liquid is 0.6 ~ 1.5 ﹕ 1.The Instant Drinks preparation that preferred employing obtains after adding more flavoring agents, time edible, patient can adjust according to the taste of oneself, facilitates patient.
The medicinal plant extraction of Cure for insomnia of the present invention is as the application of active substance for the preparation of the Chinese medicine of Cure for insomnia.
Further, described Chinese medicine is oral formulations.
Particularly, described oral formulations can be tablet, granule, electuary, capsule or pill etc.Preparation method adopts the conventional fabrication process of corresponding dosage form.
Preferably, described Chinese medicine is liquid electuary dosage form.In the medicinal plant extraction of Cure for insomnia, add corresponding flavoring agent be prepared into liquid electuary, when taking, after the liquid electuary of measured amounts, can take after adding water dilution.
Certainly, be in the consideration of the aspect such as easy to carry, described Chinese medicine is preferably the solid preparations such as tablet, granule, capsule or pill.When preparing these solid preparations, first medicinal plant extraction will be carried out powdered process, such as, spray drying process is by medicinal plant extraction powdered.And then in the medicinal plant extraction of powdered, add the fillers such as corresponding excipient prepare corresponding dosage form.
In Chinese medicine composition in the medicinal plant extraction of Cure for insomnia of the present invention, the pharmacological action of each raw material is as follows:
Semen Ziziphi Spinosae, sour in the mouth is sweet, flat.Enter the heart, spleen, liver, gallbladder four warp.There is nourishing the liver, mind calming, calm the nerves, effect of arresting sweating.Primary treatment restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.After Semen Ziziphi Spinosae fries, more fragrant, perfume (or spice) can be amusing, and can promote that gastrointestinal is to the absorption of medicine.
Semen Platycladi, nature and flavor: sweet, flat.GUIXIN, kidney, large intestine channel.There is tranquilizing by nourishing the heart, the effect of loosening bowel to relieve constipation.
Radix Polygalae, nature and flavor: toil, temperature, nontoxic.Enter the heart, liver, spleen three warp.To calm the nerves Fructus Alpiniae Oxyphyllae, eliminate the phlegm, resolving depression.Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, carbuncle skin ulcer swells.
Caulis Polygoni Multiflori, has another name called Caulis Polygoni Multiflori.Sweet in the mouth, micro-hardship, property is put down; GUIXIN, Liver Channel; There is effect of energy tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral; Cure mainly insomnia and dreamful sleep, blood deficiency general pain, numbness of the skin, rheumatic arthralgia, wind skin ulcer scabies.
In theory of Chinese medical science, insomnia multi-source in disarmony between the heart and kidney, insufficiency of vital energy and blood, discomfort in the stomach, milk-livered etc.Based on this, in the Chinese medicine composition of Cure for insomnia of the present invention, cooked Semen Ziziphi Spinosae, Semen Platycladi, Radix Polygalae fleece-flower root rattan compatibility, complement each other.Be immersed in by this four Chinese medicine in edible acidic liquid, the effective ingredient in four Chinese medicine can soak out by acidic liquid sooner more targetedly, and simultaneously in sour environment, absorbing of each effective ingredient is better, can play better therapeutic effect.Therefore, medicinal plant extraction of the present invention can tranquilizing by nourishing the heart, fills blood, and mending gallbladder needs, and nourishing the stomach, dissolves strongly fragrant gas in body.In sour environment, simultaneously by the promotion gastrointestinal of cooked Semen Ziziphi Spinosae to the effect of the absorption of medicine, improve the absorption of effective ingredient of Semen Platycladi, Radix Polygalae fleece-flower root rattan, improve the drug effect of Chinese medicine composition.Can effectively improve and effect a radical cure insomnia.And medicinal plant extraction instant of the present invention, can directly eat, or the Instant Drinks that add water.
Detailed description of the invention
Below in conjunction with embodiments of the invention, be clearly and completely described technical scheme of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
In embodiments of the invention, the benchmark of weight portion is 1g.The concrete consumption of certain other benchmark of employing all also belongs to protection scope of the present invention.
Embodiment 1
The medicinal plant extraction of the Cure for insomnia of embodiment 1 is immersed in 1500mL vinegar by 55g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20g, Semen Platycladi 15g, Radix Polygalae 10g fleece-flower root rattan 10g.Vinegar preferably protects peaceful vinegar.
The preparation method of the medicinal plant extraction of the Cure for insomnia of the present embodiment 1 is as follows: after each material pulverizing in Chinese medicine composition, add in vinegar, at 5 DEG C ~ 30 DEG C temperature, ventilation lucifugal and under the environment of drying soak 5 ~ 15 days, relative humidity is 10% ~ 20%.Cross leaching lixiviating solution and get final product.Wherein, temperature is lower, and soak time is longer; Otherwise temperature is higher, soak time is shorter.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 1 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
Embodiment 2
The medicinal plant extraction of the Cure for insomnia of embodiment 2 is immersed in 1500mL vinegar by 35g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 15g, Semen Platycladi 10g, Radix Polygalae 5g fleece-flower root rattan 5g.Vinegar preferably protects peaceful vinegar.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 2 adopts the preparation method recorded in embodiment 1 to prepare.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 2 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
Embodiment 3
The medicinal plant extraction of the Cure for insomnia of embodiment 3 is immersed in 2000mL vinegar by 75g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 25g, Semen Platycladi 20g, Radix Polygalae 15g fleece-flower root rattan 15g.Vinegar preferably protects peaceful vinegar.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 3 adopts the preparation method recorded in embodiment 1 to prepare.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 3 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
Embodiment 4
The medicinal plant extraction of the Cure for insomnia of embodiment 4 is immersed in 2700mL vinegar by 55g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20g, Semen Platycladi 15g, Radix Polygalae 10g fleece-flower root rattan 10g.Vinegar preferably protects peaceful vinegar.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 4 adopts the preparation method recorded in embodiment 1 to prepare.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 4 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
Embodiment 5
The medicinal plant extraction of the Cure for insomnia of embodiment 5 is immersed in 2200mL vinegar by 55g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20g, Semen Platycladi 15g, Radix Polygalae 10g fleece-flower root rattan 10g.Vinegar preferably protects peaceful vinegar.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 5 adopts the preparation method recorded in embodiment 1 to prepare.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 5 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
Embodiment 6
The medicinal plant extraction of the Cure for insomnia of embodiment 6 is immersed in 1500mL acid fruit extracting solution by 55g Chinese medicine composition below to prepare; Wherein, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20g, Semen Platycladi 15g, Radix Polygalae 10g fleece-flower root rattan 10g.
Wherein, described acid fruit extracting solution can select Fructus Citri Limoniae extract, Fructus Citri junoris extracting solution etc.Extraction process adopts prior art.
Acid fruit extracting solution described in the present embodiment 6 adopts Fructus Citri Limoniae extract.
The preparation method of the medicinal plant extraction of the Cure for insomnia of the present embodiment 6 is as follows: after each material pulverizing in Chinese medicine composition, add in Fructus Citri Limoniae extract, at 5 DEG C ~ 30 DEG C temperature, ventilation lucifugal and under the environment of drying soak 5 ~ 15 days, relative humidity is 10% ~ 20%.Cross leaching lixiviating solution and get final product.Wherein, temperature is lower, and soak time is longer; Otherwise temperature is higher, soak time is shorter.
The medicinal plant extraction of the Cure for insomnia of the present embodiment 6 can directly be taken, or, take add appropriate flavoring agent in medicinal plant extraction after, without the need to following process process.When taking, in medicinal plant extraction, add appropriate flavoring agent, to increase mouthfeel.Certainly, also can carry out following process, make the product of other types.
In above-described embodiment, vinegar is not limited to protect peaceful vinegar, and be the peaceful vinegar of guarantor of the ability when concrete preparation, other vinegar all can be used in the present invention.
In above-described embodiment, flavoring agent can adopt Mel, sucrose, and also can be the edible xylitol of diabetes patient, concrete consumption carries out adjusting according to practical situation.Certainly, can also add the flavoring agent of other kinds, the taste preference according to eater carries out selecting.
In above-described embodiment, each raw material of Chinese medicine composition can directly add in edible acidic liquid with bulk form, and relative prolongation soak time, ensure that the effective ingredient in block stock can by sufficient lixiviate out.
Embodiment 7
The present embodiment 7 is that the medicinal plant extraction of Cure for insomnia is as the application of active substance for the preparation of the Chinese medicine of Cure for insomnia.Described Chinese medicine is preferably oral formulations.
Described oral formulations can be tablet, granule, electuary, capsule, pill or oral liquid etc.Preparation method adopts the conventional fabrication process of corresponding dosage form.
For the consideration of the aspect such as easy to carry, described Chinese medicine is preferably the solid preparations such as tablet, granule, capsule or pill.When preparing these solid preparations, first medicinal plant extraction will be carried out powdered process, such as, spray drying process is by medicinal plant extraction powdered.And then in the medicinal plant extraction of powdered, add the fillers such as corresponding excipient prepare corresponding dosage form.
Clinical trial result:
One, case source
From the patient sought medical advice, select 600 people, wherein 90 elementary insomniacs, 180 intermediate insomniacs, 180 senior insomniacs, 150 highest insomniacs.Be divided into 6 groups, often organized 100 people, wherein, 15 elementary insomniacs, 30 intermediate insomniacs, 30 senior insomniacs, 25 highest insomniacs.
Two, situation is treated
Often organize the medicinal plant extraction that patient's correspondence takes the Cure for insomnia of embodiment 1 to embodiment 6 for first group in 6 groups to the 6th group.
Instructions of taking is: take 5 ~ 10mL medicinal plant extraction, once a day, falls asleep and drinks for first 5 ~ 30 minutes.Take 1 month cycle.When taking, foundation personal considerations, can add appropriate Mel and water is in harmonious proportion, and drinks after obtaining good mouthfeel again, as long as ensure that the dose of medicinal plant extraction is within the scope of 5 ~ 10mL.As, in 5 ~ 10mL medicinal plant extraction, add the Mel identical with medicinal plant extraction volume, then add appropriate water and be in harmonious proportion.
Three, evaluation criterion
Insomnia grade classification is four grades by this clinical trial, and patient defines the level according to practical situation.
Elementary: poor sleeping quality, although can fall asleep, can feel that sleep can not be recovered from fatigue, after waking up, still have feeling of fatigue.
Middle rank, shallow easy daydream of sleeping, self-induction is slept unreal, non-sleeping of all seemingly sleeping a night, and an eye closing is exactly dream, and once there being sound to wake up, what time no matter some early awakenings, fall asleep, and standard is waken up the three in the morning, falls asleep more difficult again, have to stare to daybreak after waking up.
Senior, difficulty falling asleep, tosses about in bed, and time for falling asleep postpones 1-3 hour than ever, and patient says original also very tired, and also sleepy is felt, can lie on a bed is exactly can't fall asleep, and that tosses about thinks some things topsy-turvy, does not calmly get off, and the length of one's sleep obviously reduces.
The superlative degree, cannot fall asleep whole night, has no tired meaning night, also often goes to toilet with getting up in the night to urinate night.Daytime, the dimmed whole body was unable, face distress.
Four, curative effect determinate standard
Effective: insomnia disappears.
Effective: insomnia grade degradation.
Invalid: it is invalid not to be downgraded to.
Five, result statistics
In first group of patient, effective: 80 people, 80%; Effective: 18 people, 18%; Invalid: 2 people, 2%.Total effective rate is 98%.
In second group of patient, effective: 75 people, 75%; Effective: 23 people, 26%; Invalid: 2 people, 4%.Total effective rate is 96%.
In 3rd group of patient, effective: 73 people, 73%; Effective: 22 people, 22%; Invalid: 5 people, 5%.Total effective rate is 95%.
In 4th group of patient, effective: 73 people, 70%; Effective: 24 people, 26%; Invalid: 3 people, 3%.Total effective rate is 97%.
In 5th group of patient, effective: 79 people, 80%; Effective: 19 people, 18%; Invalid: 2 people, 2%.Total effective rate is 98%.
In 6th group of patient, effective: 71 people, 71%; Effective: 24 people, 24%; Invalid: 5 people, 5%.Total effective rate is 95%.
The medicinal plant extraction of the Cure for insomnia of the embodiment of the present invention 1 to embodiment 6 has good therapeutical effect to insomnia, and total effective rate reaches 95% ~ 98%.
Six, typical case
Case 1 poplar, female, 35 years old, certain overseas-funded enterprise middle level leader, due to operating pressure, high strength mental work, shallow easy daydream of sleeping, intermediate insomnia.The medicinal plant extraction taking embodiment 1 Cure for insomnia has just had obvious improvement for one week, and after one month, sleep is steady and sure, and deep sleep's time is long, and sleep quality improves, and normal work of going to bed early and get up early every day, do not recur again.
Case 2 Zhu, 17 years old, high school senior, due to college entrance examination pressure, poor sleeping quality, daytime fatigue sense was serious, elementary ten seconds symptoms.The medicinal plant extraction taking embodiment 6 Cure for insomnia has just had obvious improvement for three days, and after one week, sleep is steady and sure, and sleep quality improves, spirit and QI cleaning after waking up.Do not recur again.
Case 3 goes into business certain, female, 51 years old, insomniac 7 years of this patient.Due to very high to child's expected value, from child at primary school after, center of gravity is placed on life and the school work aspect of child always, because school work is undesirable, by poor sleeping quality at the beginning, develop into the shallow and dreaminess of sleep, until develop into senior difficulty falling asleep, keep this senior difficulty falling asleep general about 7 years.Just there is obvious improvement after taking the medicinal plant extraction two weeks of embodiment 2 Cure for insomnia, easily fallen asleep, but can often wake up; After taking 1 month, improve completely, having peace of mind of sleeping now, sleep quality improves.Do not recur again.
Case 4 grandson, man, 38 years old, peasant, extraterrestrial except planting, be engaged in poultry husbandry again.Because fowl plague causes this batch of chicken all to die of illness, cause pressure economically, and suffer from serious insomnia disease, be difficult to evening fall asleep, daytime, the dimmed whole body was unable, and face distress, has no appetite, day by day becomes thin all night.Through taking the medicinal plant extraction of embodiment 5 Cure for insomnia after 5 weeks, having clear improvement, starting there is hunger sensation, having had feeding urges; After 15 days, can fall asleep, but night still has symptoms such as waking up with a start; After taking 1 month, improve completely, having peace of mind of sleeping now, sleep quality improves, and the mental status is good.Do not recur again.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.

Claims (10)

1. a medicinal plant extraction for Cure for insomnia, is characterized in that, is immersed in edible acidic liquid by Chinese medicine composition and prepares; Wherein, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 15 ~ 25 parts, Semen Platycladi 10 ~ 20 parts, 5 ~ 15 parts, Radix Polygalae 5 ~ 15 parts of fleece-flower root rattans.
2. the medicinal plant extraction of a kind of Cure for insomnia according to claim 1, is characterized in that, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 18 ~ 22 parts, Semen Platycladi 12 ~ 18 parts, 8 ~ 12 parts, Radix Polygalae 8 ~ 12 parts of fleece-flower root rattans.
3. the medicinal plant extraction of a kind of Cure for insomnia according to claim 1, is characterized in that, by weight, described Chinese medicine composition comprises following raw material: cooked Semen Ziziphi Spinosae 20 parts, Semen Platycladi 15 parts, 10 parts, Radix Polygalae 10 parts of fleece-flower root rattans.
4. the medicinal plant extraction of a kind of Cure for insomnia according to any one of claim 1 to 3, is characterized in that, the ratio of the quality of described Chinese medicine composition and the volume of edible acidic liquid is 1g ﹕ 25 ~ 50mL.
5. the medicinal plant extraction of a kind of Cure for insomnia according to claim 4, is characterized in that, the ratio of the quality of described Chinese medicine composition and the volume of edible acidic liquid is 1g ﹕ 27 ~ 30mL.
6. the medicinal plant extraction of a kind of Cure for insomnia according to claim 1,2,3 or 5, is characterized in that, described edible acidic liquid is vinegar or acid fruit extracting solution.
7. the medicinal plant extraction of a kind of Cure for insomnia according to claim 1,2,3 or 5, is characterized in that, described medicinal plant extraction is directly drunk, or drinks add flavoring agent in medicinal plant extraction after.
8. the preparation method of the medicinal plant extraction of a kind of Cure for insomnia according to any one of claim 1 to 7, is characterized in that, comprises and the Chinese medicine composition according to any one of the claims 1 to 3 is added the step of soaking in edible acidic liquid; Environmental condition during immersion is: under room temperature, ventilation lucifugal and the environment of drying.
9. the preparation method of the medicinal plant extraction of a kind of Cure for insomnia according to claim 8, is characterized in that, soak time is 5 ~ 15 days.
10. the medicinal plant extraction of a kind of Cure for insomnia according to any one of claim 1 to 7 is as the application of active substance for the preparation of the Chinese medicine of Cure for insomnia.
CN201510901946.XA 2015-12-07 2015-12-07 Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor Pending CN105326933A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510901946.XA CN105326933A (en) 2015-12-07 2015-12-07 Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510901946.XA CN105326933A (en) 2015-12-07 2015-12-07 Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor

Publications (1)

Publication Number Publication Date
CN105326933A true CN105326933A (en) 2016-02-17

Family

ID=55277839

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510901946.XA Pending CN105326933A (en) 2015-12-07 2015-12-07 Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor

Country Status (1)

Country Link
CN (1) CN105326933A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108041603A (en) * 2018-01-30 2018-05-18 哈尔滨快好药业有限公司 It is a kind of that there is health food for improving sleep effect and its preparation method and application
CN109331083A (en) * 2018-11-13 2019-02-15 温州浩然健康产业有限公司 One kind helping sleep Essence and preparation method thereof and application method
CN112220902A (en) * 2020-11-09 2021-01-15 深圳市宝安区人民医院 Traditional Chinese medicine preparation for treating phlegm-heat internal disturbance type insomnia and preparation method thereof
CN112915142A (en) * 2021-01-28 2021-06-08 河南省中医院(河南中医药大学第二附属医院) Traditional Chinese medicine scraping medium and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178754A (en) * 2010-12-08 2011-09-14 叶建斌 Formula for nerve-calming effervescent tablets and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178754A (en) * 2010-12-08 2011-09-14 叶建斌 Formula for nerve-calming effervescent tablets and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108041603A (en) * 2018-01-30 2018-05-18 哈尔滨快好药业有限公司 It is a kind of that there is health food for improving sleep effect and its preparation method and application
CN109331083A (en) * 2018-11-13 2019-02-15 温州浩然健康产业有限公司 One kind helping sleep Essence and preparation method thereof and application method
CN112220902A (en) * 2020-11-09 2021-01-15 深圳市宝安区人民医院 Traditional Chinese medicine preparation for treating phlegm-heat internal disturbance type insomnia and preparation method thereof
CN112220902B (en) * 2020-11-09 2021-11-12 深圳市宝安区人民医院 Traditional Chinese medicine preparation for treating phlegm-heat internal disturbance type insomnia and preparation method thereof
CN112915142A (en) * 2021-01-28 2021-06-08 河南省中医院(河南中医药大学第二附属医院) Traditional Chinese medicine scraping medium and preparation method thereof
CN112915142B (en) * 2021-01-28 2022-01-28 河南省中医院(河南中医药大学第二附属医院) Traditional Chinese medicine scraping medium and preparation method thereof

Similar Documents

Publication Publication Date Title
KR101090284B1 (en) Tonic comprising red ginseng and deer antlers extracts and manufacturing method thereof
CN103416625B (en) Barley piglet feed and preparation method thereof
CN105326933A (en) Traditional Chinese medicine leach liquor for treating insomnia and preparing method and application of traditional Chinese medicine leach liquor
CN104286273A (en) Application of dendrobium candidum and tea leaf product thereof
CN104906347A (en) Honeysuckle, smoked plum and Chinese olive lozenge as well as preparation method and application thereof
KR20170142756A (en) composition and method thereof
CN108686098A (en) A kind of Chinese medicine composition for gut purge defaecation
CN105475800A (en) Mango effervescent tablet and preparation method thereof
CN103416536B (en) Selenium-rich intestine moistening tea and production method thereof
CN104351757A (en) Food for improving yin deficiency constitution and preparation technology of food
CN104606663B (en) A kind of Chinese medicine for promoting Recovery and preparation method thereof
CN106360532A (en) Sleep quality improving chrysanthemum sauce
CN105192186A (en) Gingko dark green tea and preparation method thereof
CN104586977A (en) Broadleaf holly leaf granule and production method thereof
CN107712890A (en) A kind of antitoxic heart-soothing and sedative cream taste and preparation method thereof
CN104305229B (en) A kind of stem of noble dendrobium dietary fiber food and its processing method
CN103734594B (en) Sleep-assisting food and processing method thereof
CN105395896A (en) Mouth-kept liquid medicine for treating dental ulcer and preparation method
CN104664505A (en) Drink capable of improving sleep
CN104225108B (en) Treat the Chinese medicine preparation and preparation method of nocturnal fretfulness in infants
KR101439792B1 (en) Oriental medicine composition for children's underweight and respiratory organ, and oriental medicine extracts derived therefrom, and method of preparing the same
CN104606571A (en) Fresh spinach root tea substituted drink with effects of helping produce saliva and slaking thirst and preparation method thereof
CN104225379A (en) Traditional Chinese medicine formula for treating gastritis
CN104940332B (en) A kind of Fructooligosaccharidcomposition composition and preparation method thereof of defaecation and reduction flatulence
CN109170052A (en) A kind of dendrobium nobile stomach-nourishing health tea and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160217