CN104189217A - Traditional Chinese medicine composition for treating diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating diarrhea and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating diarrhea. The composition is prepared from the following raw material component: agastache rugosus, angelica sinensis, semen euryales, agrimonia pilosa ledeb, licorice root, rhizoma atractylodis macrocephalae, cinnamon, manyprickle acanthopanax root, scutellaria baicalensis, hawthorn, houttuynia cordata, medicated leaven, funnel, purple perilla and corydalis tuber. The traditional Chinese medicine composition is mainly used for treating diarrhea in clinical application to play roles in strengthening spleen, harmonizing stomaching, tonifying qi, relieving diarrhea and solidifying intestines, is simple in medicine preparation, quick in response and short in course of treatment, and has a good treatment effect on acute and chronic diarrhea.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly, the present invention relates to a kind ofly for curing mainly the Chinese medicine composition of diarrhoea, the invention still further relates to the preparation method of described Chinese medicine composition.
Background technology
Diarrhoea (diarrhea) is a kind of common sympton, refers to that defecation frequency obviously exceedes on ordinary days the frequency of custom, and excrement matter is thin, and moisture increases, and every day, feces volume exceeded 200g, or containing not digest food or pus and blood, mucus.Diarrhoea is often with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea point acute and chronic two classes.Acute diarrhea is fallen ill sharply, and the course of disease is within 2～3 weeks.Chronic diarrhea refers to the course of disease more than two months or the recurrent diarrhoea of intermission in 2～4 weeks.
Diarrhoea not only can affect daily life and work, and long-time diarrhoea also can cause very large harm to health, and the interior moisture of such as body and a large amount of losses of trace element etc., therefore will treat in time to suffering from diarrhoea, can not general idea.
At present, the modes that adopt oral anti-inflammatory drug or injection are treated more clinically, although instant effect, side effects of pharmaceutical drugs are obvious, and human body is had to considerable influence.Also there is multiple medicine for external use, but mostly exist therapeutic effect undesirable, obstinate, cost is higher, and the course for the treatment of is longer, the problem such as produce effects slowly.
Existing marketed drugs Chinese medicine has Medilac-Vita, treating infant diarrhea speed to stop and the French dioctahedral smectite of winning good fortune pharmacy, Medilac-Vita contains two kinds of viable bacterias: bacillus subtilis and enterococcus, can directly supplement normal physiological flora, suppress pathogenic bacterium, promote digestion, the absorption of nutrient substance, suppress generation and the absorption of intestinal source property toxin, reach the object of adjusting dysbacteriosis in intestinal, though this medication effect is good, easily repeatedly, radical rate is low for the state of an illness.Rush down speed and stop by Herba Euphorbiae Humifusae, obtain Siberian cocklebur, Radix Glycyrrhizae, catechu etc. and form, have the effect such as clearing heat and expelling damp, invigorating the spleen to arrest diarrhea, dispel emphatically pathogen, repair deficiency, recovers digestive and absorptive functions, but lacks the defencive function to gastrointestinal.Dioctahedral smectite mainly, by gastrointestinal protection, stops bacterial virus in gastrointestinal field planting, and cell is repaired as early as possible, the auxiliary reparation suffering for want of medical supplies and adjusting humoral effect.
Object of the present invention overcomes that Western medicine side effect is large exactly, curative effect not significantly or the reason such as form of Chinese drug, the deficiency of the technology such as curative effect is unstable, according to traditional Chinese medical science prescription and preparation principle, Chinese medicine composition is developed meticulously, the advantages such as one is pointed by force, good effect, the cycle is short, price is low, have no side effect are provided, can make again patient take like a shot, can treat preferably the pure Chinese medicinal preparation of diarrhoea.In side, each medicine is worked in coordination with onset mutually, plays effect of spleen invigorating, stomach function regulating, QI invigorating, antidiarrheal, solid intestinal; And prepared by medicine simple, rapid-action, short treating period, acute and chronic diarrhoea is all had to good therapeutical effect.
Summary of the invention
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of diarrhoea, it is characterized in that being prepared from by following raw material components: Herba Pogostemonis, Radix Angelicae Sinensis, Semen Euryales, Herba Agrimoniae, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Radix Et Caulis Acanthopanacis Senticosi, Radix Scutellariae, Fructus Crataegi, Herba Houttuyniae, Massa Medicata Fermentata, Fructus Foeniculi, Folium Perillae, Rhizoma Corydalis.
Wherein, Herba Pogostemonis 10-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Semen Euryales 10-25 weight portion, Herba Agrimoniae 10-20 weight portion, Radix Glycyrrhizae 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-25 weight portion, Cortex Cinnamomi 10-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 10-20 weight portion, Radix Scutellariae 20-30 weight portion, Fructus Crataegi 20-30 weight portion, Herba Houttuyniae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion, Fructus Foeniculi 15-25 weight portion, Folium Perillae 10-20 weight portion, Rhizoma Corydalis 15-25 weight portion.
Preferably, Herba Pogostemonis 20-30 weight portion, Radix Angelicae Sinensis 24-30 weight portion, Semen Euryales 17-25 weight portion, Herba Agrimoniae 15-20 weight portion, Radix Glycyrrhizae 22-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Cortex Cinnamomi 15-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 16-20 weight portion, Radix Scutellariae 24-30 weight portion, Fructus Crataegi 26-30 weight portion, Herba Houttuyniae 16-20 weight portion, Massa Medicata Fermentata 17-20 weight portion, Fructus Foeniculi 21-25 weight portion, Folium Perillae 16-20 weight portion, Rhizoma Corydalis 21-25 weight portion.
Further preferably, Herba Pogostemonis 20 weight portions, Radix Angelicae Sinensis 24 weight portions, Semen Euryales 17 weight portions, Herba Agrimoniae 15 weight portions, Radix Glycyrrhizae 22 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Cortex Cinnamomi 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 16 weight portions, Radix Scutellariae 24 weight portions, Fructus Crataegi 26 weight portions, Herba Houttuyniae 16 weight portions, Massa Medicata Fermentata 17 weight portions, Fructus Foeniculi 21 weight portions, Folium Perillae 16 weight portions, Rhizoma Corydalis 21 weight portions.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of Chinese medicine composition for the treatment of diarrhoea, and preparation process is:
A. the each component in described raw material components is mixed in proportion, puts into 5 times of water gagings, heating and refluxing extraction 2 times, each 30 minutes～45 minutes, extract active ingredient, 2 extracting solution are merged and left standstill;
B. the medicinal residues of crossing through water extraction in step a are put into 5 times of amount ethanol, heating and refluxing extraction 2 times, each 20 minutes～30 minutes, merges 2 extracting solution to leave standstill again;
C. above-mentioned two kinds of extracting solution are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.03-0.06MPa, temperature remains on 60-80 DEG C, and being concentrated into relative density is 1.20, and the extractum that temperature to 60 is DEG C-70 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
The present invention also provides the application of above-mentioned raw materials component in the Chinese medicine composition of preparation treatment diarrhoea.
Beneficial effect of the present invention:
Technical problem to be solved by this invention is, the Chinese medicine composition that provides a kind for the treatment of to suffer from diarrhoea, and described Chinese medicine composition is mainly used in the treatment of diarrhoea clinically, plays effect of spleen invigorating, stomach function regulating, QI invigorating, antidiarrheal, solid intestinal; And prepared by medicine simple, rapid-action, short treating period, acute and chronic diarrhoea is all had to good therapeutical effect.
Detailed description of the invention
The invention provides a kind of Chinese medicine composition for the treatment of diarrhoea, it is characterized in that being prepared from by following raw material components: Herba Pogostemonis, Radix Angelicae Sinensis, Semen Euryales, Herba Agrimoniae, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Radix Et Caulis Acanthopanacis Senticosi, Radix Scutellariae, Fructus Crataegi, Herba Houttuyniae, Massa Medicata Fermentata, Fructus Foeniculi, Folium Perillae, Rhizoma Corydalis.
Wherein, Herba Pogostemonis 10-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Semen Euryales 10-25 weight portion, Herba Agrimoniae 10-20 weight portion, Radix Glycyrrhizae 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-25 weight portion, Cortex Cinnamomi 10-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 10-20 weight portion, Radix Scutellariae 20-30 weight portion, Fructus Crataegi 20-30 weight portion, Herba Houttuyniae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion, Fructus Foeniculi 15-25 weight portion, Folium Perillae 10-20 weight portion, Rhizoma Corydalis 15-25 weight portion.
Preferably, Herba Pogostemonis 20-30 weight portion, Radix Angelicae Sinensis 24-30 weight portion, Semen Euryales 17-25 weight portion, Herba Agrimoniae 15-20 weight portion, Radix Glycyrrhizae 22-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Cortex Cinnamomi 15-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 16-20 weight portion, Radix Scutellariae 24-30 weight portion, Fructus Crataegi 26-30 weight portion, Herba Houttuyniae 16-20 weight portion, Massa Medicata Fermentata 17-20 weight portion, Fructus Foeniculi 21-25 weight portion, Folium Perillae 16-20 weight portion, Rhizoma Corydalis 21-25 weight portion.
Further preferably, Herba Pogostemonis 20 weight portions, Radix Angelicae Sinensis 24 weight portions, Semen Euryales 17 weight portions, Herba Agrimoniae 15 weight portions, Radix Glycyrrhizae 22 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Cortex Cinnamomi 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 16 weight portions, Radix Scutellariae 24 weight portions, Fructus Crataegi 26 weight portions, Herba Houttuyniae 16 weight portions, Massa Medicata Fermentata 17 weight portions, Fructus Foeniculi 21 weight portions, Folium Perillae 16 weight portions, Rhizoma Corydalis 21 weight portions.
The present invention also provides a kind of preparation method of Chinese medicine composition for the treatment of diarrhoea, and preparation process is:
A. the each component in described raw material components is mixed in proportion, puts into 5 times of water gagings, heating and refluxing extraction 2 times, each 30 minutes～45 minutes, extract active ingredient, 2 extracting solution are merged and left standstill;
B. the medicinal residues of crossing through water extraction in step a are put into 5 times of amount ethanol, heating and refluxing extraction 2 times, each 20 minutes～30 minutes, merges 2 extracting solution to leave standstill again;
C. above-mentioned two kinds of extracting solution are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.03-0.06MPa, temperature remains on 60-80 DEG C, and being concentrated into relative density is 1.20, and the extractum that temperature to 60 is DEG C-70 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
The present invention also provides the application of above-mentioned raw materials component in the Chinese medicine composition of preparation treatment diarrhoea.
The present invention develops Chinese medicine composition meticulously according to traditional Chinese medical science prescription and preparation principle, the advantages such as one is pointed by force, good effect, the cycle is short, price is low, have no side effect are provided, can make again patient take like a shot, can treat preferably the pure Chinese medicinal preparation of diarrhoea.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
embodiment 1:
Get Herba Pogostemonis 10g, Radix Angelicae Sinensis 15g, Semen Euryales 10g, Herba Agrimoniae 10g, Radix Glycyrrhizae 15g, Rhizoma Atractylodis Macrocephalae 15g, Cortex Cinnamomi 10g, Radix Et Caulis Acanthopanacis Senticosi 10g, Radix Scutellariae 20g, Fructus Crataegi 20g, Herba Houttuyniae 10g, Massa Medicata Fermentata 10g, Fructus Foeniculi 15g, Folium Perillae 10g, Rhizoma Corydalis 15g, after chopping, put into 5 times of water gagings, heating and refluxing extraction 2 times, each 30 minutes, extract active ingredient, 2 extracting solution are merged and left standstill; The medicinal residues of crossing with water extraction are put into 5 times of amount ethanol, and heating and refluxing extraction 2 times, each 20 minutes, merges 2 extracting solution to leave standstill; Above-mentioned two kinds of extracting solution are merged, and decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.03MPa, temperature remains on 60 DEG C, and being concentrated into relative density is 1.20, and the extractum of temperature to 60 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
embodiment 2:
Get Herba Pogostemonis 30g, Radix Angelicae Sinensis 30g, Semen Euryales 25g, Herba Agrimoniae 20g, Radix Glycyrrhizae 30g, Rhizoma Atractylodis Macrocephalae 25g, Cortex Cinnamomi 20g, Radix Et Caulis Acanthopanacis Senticosi 20g, Radix Scutellariae 30g, Fructus Crataegi 30g, Herba Houttuyniae 20g, Massa Medicata Fermentata 20g, Fructus Foeniculi 25g, Folium Perillae 20g, Rhizoma Corydalis 25g, after chopping, put into 5 times of water gagings, heating and refluxing extraction 2 times, each 45 minutes, extract active ingredient, 2 extracting solution are merged and left standstill; The medicinal residues of crossing with water extraction are put into 5 times of amount ethanol, and heating and refluxing extraction 2 times, each 30 minutes, merges 2 extracting solution to leave standstill; Above-mentioned two kinds of extracting solution are merged, and decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.06MPa, temperature remains on 80 DEG C, and being concentrated into relative density is 1.20, and the extractum of temperature to 70 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
embodiment 3:
Get Herba Pogostemonis 20g, Radix Angelicae Sinensis 24g, Semen Euryales 17g, Herba Agrimoniae 15g, Radix Glycyrrhizae 22g, Rhizoma Atractylodis Macrocephalae 20g, Cortex Cinnamomi 15g, Radix Et Caulis Acanthopanacis Senticosi 16g, Radix Scutellariae 24g, Fructus Crataegi 26g, Herba Houttuyniae 16g, Massa Medicata Fermentata 17g, Fructus Foeniculi 21g, Folium Perillae 16g, Rhizoma Corydalis 21g, after chopping, put into 5 times of water gagings, heating and refluxing extraction 2 times, each 40 minutes, extract active ingredient, 2 extracting solution are merged and left standstill; The medicinal residues of crossing with water extraction are put into 5 times of amount ethanol, and heating and refluxing extraction 2 times, each 25 minutes, merges 2 extracting solution to leave standstill; Above-mentioned two kinds of extracting solution are merged, and decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.05MPa, temperature remains on 70 DEG C, and being concentrated into relative density is 1.20, and the extractum of temperature to 65 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
embodiment 4:
Clinical experiment: selected 180 routine diarrhea patients at random, between age 14-45 year, the mean age is 29.2 years old, and the course of disease is the shortest is 5 days, and the longest is February, random packet, test group 90 examples, matched group 90 examples.
Therapeutic Method: Chinese medicine composition prepared by the oral embodiment of the present invention 1-3 of test group, every day 2-3 time, each 21 week is 1 course for the treatment of.Matched group is oral rushes down vertical stopping, and every day 2-3 time, 1-2 grain, 1 week is 1 course for the treatment of at every turn.
Diagnostic criteria:
1, symptom: stool every day more than 3 times, excrement matter is thin or as water sample.
2, dysentery and infectious diarrhea are got rid of in feces examination.
Efficacy assessment standard:
1, cure: stool every day 1 time or 2 times, amount, matter are all normal.
2, take a turn for the better: times of defecation reduces, but still thin.
3, invalid: before and after taking medicine, symptom is not improved.
Therapeutic outcome:
In the routine patient of test group 90,1 recovery from illness course for the treatment of of general the lighter, 2 recoveries from illness course for the treatment of of severe one, wherein, cure 74 examples, and cure rate accounts for 82.2%, 12 examples that take a turn for the better, obvious effective rate accounts for 13.3%, and total effective rate is 95.5%, invalid 4 examples, inefficiency accounts for 4.5%.
In the routine patient of matched group 90, after 2 courses for the treatment of, cure 59 examples, cure rate accounts for 65.6%, 15 examples that take a turn for the better, and obvious effective rate accounts for 16.7%, and total effective rate is 82.2%, invalid 16 examples, inefficiency accounts for 17.8%.
Curative effect comparison: treatment group total effective rate and cure rate, apparently higher than matched group, are learned and processed by statistics, and difference all has very significant (P < 0.01).
Model case:
Case 1: Lee, man, 18 years old, first visit, for diarrhoea (diarrhea due to deficiency and coldness), was taken this medicine after three days, and the state of an illness obviously alleviates, then uses after one day, cures completely, not recurrence.
Case 2: sternly certain, female, 33 years old, accidentally suffer from cold and occur diarrhoea in medical first three sky, fever, suffering from diarrhoea, feel sick, gush thing is watery stool, accompanies indigestion food.I degree dehydration looks, take medicine of the present invention after 2 days, above-mentioned symptom is all clearly better, then continue with after one day, symptomatology disappearance, has no recurrence.
Case 3: Zhao so-and-so, man, 47 years old, causes diarrhoea for 4-5 days before medical because suffering from cold.To gush thing be loose stool, be water sample or egg style, amount is many, every day more than 10 times.Through fluid infusion, application antibiotic and oral antidiarrheal 2 days, symptom was without improvement.Take medicine of the present invention, 4 days symptoms of medication are clearly better, recovery from illness in 6 days, not recurrence.
Conclusion: Chinese medicine composition of the present invention is rapid-action, and treatment rate is high, and treatment time is short, has good effect, and does not find toxic and side effects, is the good medicine of prevention and treatment diarrhoea, is worthy of popularization.
The above, be only preferred embodiment of the present invention, is not the restriction of the present invention being made to other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (6)
1. treat a Chinese medicine composition for diarrhoea, it is characterized in that being prepared from by following raw material components: Herba Pogostemonis, Radix Angelicae Sinensis, Semen Euryales, Herba Agrimoniae, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Cortex Cinnamomi, Radix Et Caulis Acanthopanacis Senticosi, Radix Scutellariae, Fructus Crataegi, Herba Houttuyniae, Massa Medicata Fermentata, Fructus Foeniculi, Folium Perillae, Rhizoma Corydalis.
2. according to the Chinese medicine composition of claim 1, wherein, Herba Pogostemonis 10-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Semen Euryales 10-25 weight portion, Herba Agrimoniae 10-20 weight portion, Radix Glycyrrhizae 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-25 weight portion, Cortex Cinnamomi 10-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 10-20 weight portion, Radix Scutellariae 20-30 weight portion, Fructus Crataegi 20-30 weight portion, Herba Houttuyniae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion, Fructus Foeniculi 15-25 weight portion, Folium Perillae 10-20 weight portion, Rhizoma Corydalis 15-25 weight portion.
3. according to the Chinese medicine composition of claim 2, wherein, Herba Pogostemonis 20-30 weight portion, Radix Angelicae Sinensis 24-30 weight portion, Semen Euryales 17-25 weight portion, Herba Agrimoniae 15-20 weight portion, Radix Glycyrrhizae 22-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Cortex Cinnamomi 15-20 weight portion, Radix Et Caulis Acanthopanacis Senticosi 16-20 weight portion, Radix Scutellariae 24-30 weight portion, Fructus Crataegi 26-30 weight portion, Herba Houttuyniae 16-20 weight portion, Massa Medicata Fermentata 17-20 weight portion, Fructus Foeniculi 21-25 weight portion, Folium Perillae 16-20 weight portion, Rhizoma Corydalis 21-25 weight portion.
4. according to the Chinese medicine composition of claim 1-3, wherein, Herba Pogostemonis 20 weight portions, Radix Angelicae Sinensis 24 weight portions, Semen Euryales 17 weight portions, Herba Agrimoniae 15 weight portions, Radix Glycyrrhizae 22 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Cortex Cinnamomi 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 16 weight portions, Radix Scutellariae 24 weight portions, Fructus Crataegi 26 weight portions, Herba Houttuyniae 16 weight portions, Massa Medicata Fermentata 17 weight portions, Fructus Foeniculi 21 weight portions, Folium Perillae 16 weight portions, Rhizoma Corydalis 21 weight portions.
5. the preparation method of the Chinese medicine composition of any one in claim 1-4, is characterized in that, preparation process is:
A. the each component in described raw material components is mixed in proportion, puts into 5 times of water gagings, heating and refluxing extraction 2 times, each 30 minutes～45 minutes, extract active ingredient, 2 extracting solution are merged and left standstill;
B. the medicinal residues of crossing through water extraction in step a are put into 5 times of amount ethanol, heating and refluxing extraction 2 times, each 20 minutes～30 minutes, merges 2 extracting solution to leave standstill again;
C. above-mentioned two kinds of extracting solution are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.6g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.04; Be decompressed to 0.03-0.06MPa, temperature remains on 60-80 DEG C, and being concentrated into relative density is 1.20, and the extractum that temperature to 60 is DEG C-70 DEG C, puts into oven for drying by extractum and make powder, sieves, and 1:6 adds soybean oil by weight, mixes, and makes soft capsule.
6. the application of the raw material components of any one in the Chinese medicine composition of preparation treatment diarrhoea in claim 1-4.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105494928A (en) * | 2015-12-03 | 2016-04-20 | 闫冷 | Feed additive for treating diarrhea of pigeons |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682847A (en) * | 2005-03-02 | 2005-10-19 | 李平 | Medicine for colitis |
| CN1814268A (en) * | 2005-02-05 | 2006-08-09 | 王福华 | Chinese herbal medicine preparation for quickly treating acute and chronial diarrhea, bloody flux and enteritis |
| CN103041281A (en) * | 2013-01-28 | 2013-04-17 | 张萍 | Traditional Chinese medicine composition for treating infantile diarrhea |
| CN103263615A (en) * | 2013-06-09 | 2013-08-28 | 张玉华 | Traditional Chinese medicine preparation for treating stomach illness, enteritis and cholecystitis and preparation method thereof |
-
2014
- 2014-09-05 CN CN201410450945.3A patent/CN104189217A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1814268A (en) * | 2005-02-05 | 2006-08-09 | 王福华 | Chinese herbal medicine preparation for quickly treating acute and chronial diarrhea, bloody flux and enteritis |
| CN1682847A (en) * | 2005-03-02 | 2005-10-19 | 李平 | Medicine for colitis |
| CN103041281A (en) * | 2013-01-28 | 2013-04-17 | 张萍 | Traditional Chinese medicine composition for treating infantile diarrhea |
| CN103263615A (en) * | 2013-06-09 | 2013-08-28 | 张玉华 | Traditional Chinese medicine preparation for treating stomach illness, enteritis and cholecystitis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 叶孝礼: "婴幼儿泄泻的中医治疗探讨", 《中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105494928A (en) * | 2015-12-03 | 2016-04-20 | 闫冷 | Feed additive for treating diarrhea of pigeons |
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Application publication date: 20141210 |
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| RJ01 | Rejection of invention patent application after publication |