CN103861004A - Traditional Chinese medicine external application agent for treating knee osteoarthritis and nursing method - Google Patents
Traditional Chinese medicine external application agent for treating knee osteoarthritis and nursing method Download PDFInfo
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- CN103861004A CN103861004A CN201410106181.6A CN201410106181A CN103861004A CN 103861004 A CN103861004 A CN 103861004A CN 201410106181 A CN201410106181 A CN 201410106181A CN 103861004 A CN103861004 A CN 103861004A
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Abstract
The invention discloses a traditional Chinese medicine external application agent for treating knee osteoarthritis which belongs to the category of heumatism, arthralgia, muscular rheumatism and the like. Kidney qi deficiency is the root of osteoarthritis. Traditional Chinese medicines such as silverweed cinquefoil roots, alectoria asiatica du rietz, polygonum divaricatum L, herb of carpet thyme, Alpinia japonica, aconitum volubile, roots or leavesof narrowleaf burmann cinnamon, ophiorrhiza japonica, derris eriocarpa how and nipponian greenbrier rhizome and roots which have the functions of tonifying kidney and spleen, promoting blood circulation and dredging tenons, expelling wind and removing cold and activating meridians to stop pain are selected to prepare the external application agent. Through clinical test, the total effective rate is 97.1% which is remarkably superior to 71.4% of the control group, and the curative effect is remarkable.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of external application of Chinese medicine agent for the treatment of knee joint osseous arthritis.
Background technology
Knee joint osseous arthritis is commonly encountered diseases, the frequently-occurring disease of middle-aged and elderly people, and its main pathological change is articular cartilage degenerative change.Western medical treatment adopts oral diclofenac sodium enteric-coated tablets to treat, and long-term taking can produce stomachache, and diarrhoea is felt sick, dyspepsia, and the side effect such as abdominal distention, even can cause damage to liver.Adopt the outer coating method treatment of the traditional Chinese medical science, the Herbal medicines for external use of application relaxing muscles and tendons to promote blood circulation, expelling wind and cold, removing obstruction in the collateral to relieve pain, pass through Drug Percutaneous Absorption, directly act on affected part, knee joint blood circulation is improved, promote inflammatory resolution, relieve muscle spasms, accelerate articular cartilage metabolism to reach, promote the object that articular cartilage is repaired.
Summary of the invention
The object of this invention is to provide a kind of external application of Chinese medicine agent for the treatment of knee joint osseous arthritis.Asthenia of renal qi is the basic of osteoarthritis morbidity, and the channels stasis blocking causing with other reasons causing is thus the key link of pathogenesis.Primary disease belongs to the categories such as Chinese medicine " rheumatism involving the bone ", " arthromyodynia ", " muscular rheumatism ".Control suitable kidney and spleen invigorating, relaxing muscles and tendons to promote blood circulation, expelling wind and cold, removing obstruction in the collateral to relieve pain.
The object of the invention is to be achieved through the following technical solutions, the external application of Chinese medicine agent of this treatment knee joint osseous arthritis is made up of the Chinese medicine of following weight portion: Radix potentillae anserinae 15-25 part, Alectoria asiatica Du Rietz 5-10 part, Radix polygoni divaricati 25-30 part, Herba Thymi 9-12 part, Alpinia japonica (Thunb.) Miq. 3-6 part, Radix aconiti volubilis 0.3-0.6 part, Radix seu Folium Cinnamomi angustifolii 6-9 part, Herba ophiorrhizae japonicae 15-25 part, Radix Millettiae typicae 15-18 part, Rhizoma Smilacis nipponicae 6-12 part.
Preferably, 20 parts of Radix potentillae anserinae, 7 parts of Alectoria asiatica Du Rietzs, 27.5 parts of Radix polygoni divaricaties, 10 parts of Herba Thymi, 4 parts of Alpinia japonica (Thunb.) Miq.s, 0.4 part of Radix aconiti volubilis, 7 parts of Radix seu Folium Cinnamomi angustifolii, 20 parts of Herba ophiorrhizae japonicaes, 16 parts of Radix Millettiae typicaes, 9 parts of Rhizoma Smilacis nipponicae.
Preparation method is by above-mentioned Chinese medicine pulverization, and wine and water add according to the ratio of 1: 1, mix well into pasty state for subsequent use.
In side: Radix potentillae anserinae vigorate qi and replenish the blood, invigorating spleen and reinforcing stomach, dampness removing; Alectoria asiatica Du Rietz enriching yin and nourishing kidney and water detumescence; Radix polygoni divaricati the kidney invigorating, dispelling cold and dampness; Herba Thymi warming spleen and stomach for dispelling cold, wind-expelling pain-stopping; Alpinia japonica (Thunb.) Miq. warming spleen and stomach for dispelling cold, expelling wind and activating blood circulation; Radix aconiti volubilis wind-damp dispelling, dispersing cold for relieving pain; Radix seu Folium Cinnamomi angustifolii wind-damp dispelling, dispersing cold for relieving pain, relaxing muscles and tendons and activating QI and blood in the collateral; Herba ophiorrhizae japonicae promoting blood circulation to remove blood stasis; Radix Millettiae typicae eliminating stasis to stop pain, detumescence are calmed the nerves; Rhizoma Smilacis nipponicae relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain.
Clinical data
1, the equal clinical diagnosis of the routine patient of physical data 140 is knee joint osseous arthritis, male 80 examples, female's 60 examples, age 25-72 year, the course of disease 1 month to 6 years.140 routine patients are divided into treatment group 70 examples at random, matched group 70 examples.Two groups of sexes, age, the course of disease, state of an illness no significant difference (P>0.05), have comparability.
2, diagnostic criteria knee joint activity is dumb, can not be movable immediately after sitting, for a long time station or rest, and feel ankylosis, walks about and relaxs one's muscles rear sense activity freely.The visible knee joint mild swelling of health check-up, movable joint has slight rattler, the grating of creaking, and tuberosity or streak thing can be touched in knee joint inner side, touch and have and ache on time, atrophy that knee joint peripheral muscle is slight.Lab testing: knee joint hyperosteogeny is shown in x-ray inspection, and joint space narrows, subchondral bone has sclerosis and blister cavities to form, epiphysis distortion in late period, articular surface is uneven.
3, Therapeutic Method treatment group is used external application of Chinese medicine agent of the present invention, take Radix potentillae anserinae 20g, Alectoria asiatica Du Rietz 7g, Radix polygoni divaricati 27.5g, Herba Thymi 10g, Alpinia japonica (Thunb.) Miq. 4g, Radix aconiti volubilis 0.4g, Radix seu Folium Cinnamomi angustifolii 7g, Herba ophiorrhizae japonicae 20g, Radix Millettiae typicae 16g, Rhizoma Smilacis nipponicae 9g, pulverization, wine and water add according to the ratio of 1: 1, mix well into pasty state, appropriate uniform fold Ipsilateral knee joint, cotton paper bandaging is fixed, and within 3 days, changes 1 time.Matched group is taken diclofenac sodium enteric-coated tablets treatment, each 50mg, every day 2 times.Be two months two groups of courses for the treatment of.
4, criterion of therapeutical effect is cured: symptom and sign disappears completely, and range of activity is bent and stretched at 0-135 degree in joint.Effective: symptom disappears substantially, without swelling, pain while occasionally having activity, when walking, without pain, range of activity is bent and stretched at 0-135 degree in joint, does not affect work and life.Effective: symptom is improved, and still has mild pain when walking, upper slightly sense inconvenience downstairs, joint motion is slightly limited.Invalid: symptom and sign is not improved.
5, therapeutic outcome treatment group 70 examples, wherein clinical cure 21 examples (30%), effective 21 examples (30%), effective 26 examples (37.1%), invalid 2 examples (2.9%), total effective rate 97.1%.Matched group 70 examples, wherein clinical cure 10 examples (14.3%), effective 21 examples (30%), effective 19 examples (27.1%), invalid 20 examples (28.6%), total effective rate 71.4%.Two groups of comparisons, treatment group clinical cure rate, total effective rate are obviously better than matched group, and difference has significance, (P<0.01).
The specific embodiment
Embodiment mono-: take Radix potentillae anserinae 20g, Alectoria asiatica Du Rietz 7g, Radix polygoni divaricati 27.5g, Herba Thymi 10g, Alpinia japonica (Thunb.) Miq. 4g, Radix aconiti volubilis 0.4g, Radix seu Folium Cinnamomi angustifolii 7g, Herba ophiorrhizae japonicae 20g, Radix Millettiae typicae 16g, Rhizoma Smilacis nipponicae 9g, by above-mentioned Chinese medicine pulverization, wine and water add according to the ratio of 1: 1, mix well into pasty state for subsequent use.
Embodiment bis-: take Radix potentillae anserinae 25g, Alectoria asiatica Du Rietz 5g, Radix polygoni divaricati 25g, Herba Thymi 9g, Alpinia japonica (Thunb.) Miq. 6g, Radix aconiti volubilis 0.3g, Radix seu Folium Cinnamomi angustifolii 9g, Herba ophiorrhizae japonicae 15g, Radix Millettiae typicae 18g, Rhizoma Smilacis nipponicae 6g, by above-mentioned Chinese medicine pulverization, wine and water add according to the ratio of 1: 1, mix well into pasty state for subsequent use.
Embodiment tri-: take Radix potentillae anserinae 15g, Alectoria asiatica Du Rietz 10g, Radix polygoni divaricati 30g, Herba Thymi 12g, Alpinia japonica (Thunb.) Miq. 3g, Radix aconiti volubilis 0.6g, Radix seu Folium Cinnamomi angustifolii 6g, Herba ophiorrhizae japonicae 25g, Radix Millettiae typicae 15g, Rhizoma Smilacis nipponicae 12g, by above-mentioned Chinese medicine pulverization, wine and water add according to the ratio of 1: 1, mix well into pasty state for subsequent use.
Claims (2)
1. treat an external application of Chinese medicine agent for knee joint osseous arthritis, it is characterized in that this external application of Chinese medicine agent is made up of the Chinese medicine of following weight portion: Radix potentillae anserinae 15-25 part, Alectoria asiatica Du Rietz 5-10 part, Radix polygoni divaricati 25-30 part, Herba Thymi 9-12 part, Alpinia japonica (Thunb.) Miq. 3-6 part, Radix aconiti volubilis 0.3-0.6 part, Radix seu Folium Cinnamomi angustifolii 6-9 part, Herba ophiorrhizae japonicae 15-25 part, Radix Millettiae typicae 15-18 part, Rhizoma Smilacis nipponicae 6-12 part.
2. a kind of external application of Chinese medicine agent for the treatment of knee joint osseous arthritis as claimed in claim 1, is characterized in that this external application of Chinese medicine agent is made up of the Chinese medicine of following weight portion: 20 parts of Radix potentillae anserinae, 7 parts of Alectoria asiatica Du Rietzs, 27.5 parts of Radix polygoni divaricaties, 10 parts of Herba Thymi, 4 parts of Alpinia japonica (Thunb.) Miq.s, 0.4 part of Radix aconiti volubilis, 7 parts of Radix seu Folium Cinnamomi angustifolii, 20 parts of Herba ophiorrhizae japonicaes, 16 parts of Radix Millettiae typicaes, 9 parts of Rhizoma Smilacis nipponicae.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410106181.6A CN103861004B (en) | 2014-03-14 | 2014-03-14 | A kind of external traditional Chinese medicinal application and care method treating knee joint osseous arthritis |
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| CN201410106181.6A CN103861004B (en) | 2014-03-14 | 2014-03-14 | A kind of external traditional Chinese medicinal application and care method treating knee joint osseous arthritis |
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| CN103861004B CN103861004B (en) | 2016-06-08 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104606305A (en) * | 2015-03-01 | 2015-05-13 | 李健 | Pharmaceutical composition for reducing serum cholesterol level and preparation process thereof |
| CN104922322A (en) * | 2015-05-31 | 2015-09-23 | 唐志君 | Traditional Chinese medicine external lotion for treating knee osteoarthritis and nursing method |
| CN105250860A (en) * | 2015-11-06 | 2016-01-20 | 高举梅 | Traditional Chinese medicine preparation for treating cold-damp block type rheumatoid gonitis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110604A (en) * | 1995-01-05 | 1995-10-25 | 赵经南 | Medicinal liquor for treatment of arthritis and promoting collateral and channels |
| CN1176825A (en) * | 1996-09-16 | 1998-03-25 | 阎静 | Medicated wine for sauna bath |
-
2014
- 2014-03-14 CN CN201410106181.6A patent/CN103861004B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110604A (en) * | 1995-01-05 | 1995-10-25 | 赵经南 | Medicinal liquor for treatment of arthritis and promoting collateral and channels |
| CN1176825A (en) * | 1996-09-16 | 1998-03-25 | 阎静 | Medicated wine for sauna bath |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104606305A (en) * | 2015-03-01 | 2015-05-13 | 李健 | Pharmaceutical composition for reducing serum cholesterol level and preparation process thereof |
| CN104922322A (en) * | 2015-05-31 | 2015-09-23 | 唐志君 | Traditional Chinese medicine external lotion for treating knee osteoarthritis and nursing method |
| CN105250860A (en) * | 2015-11-06 | 2016-01-20 | 高举梅 | Traditional Chinese medicine preparation for treating cold-damp block type rheumatoid gonitis |
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| Publication number | Publication date |
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| CN103861004B (en) | 2016-06-08 |
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