CN105435210A - Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof - Google Patents

Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof Download PDF

Info

Publication number
CN105435210A
CN105435210A CN201610072259.6A CN201610072259A CN105435210A CN 105435210 A CN105435210 A CN 105435210A CN 201610072259 A CN201610072259 A CN 201610072259A CN 105435210 A CN105435210 A CN 105435210A
Authority
CN
China
Prior art keywords
radix
rhizoma
chinese medicine
traditional chinese
raw material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610072259.6A
Other languages
Chinese (zh)
Inventor
高本梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610072259.6A priority Critical patent/CN105435210A/en
Publication of CN105435210A publication Critical patent/CN105435210A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/746—Morinda
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and a preparation method thereof. The traditional Chinese medicine oriented permeable drug treatment liquid is prepared from traditional Chinese medicine raw materials, lidocaine injection with western medicine accounting for 20%, (3 ml of the injection is used per person each time) and vitamin B12 injection (1 mg of the injection is used for per person each time); the traditional Chinese medicine raw materials include ground beeltles, radix angelicae tuhuo, teasel roots, notopterygium roots, ligusticum wallichii, safflower carthamus, radices sileris, cortex albiziae, fructus forsythia, scutellaria baicalensis, isatis roots, homalomena occulta, radix clematidis, cassia twigs, cleansing rhizoma corydalis, scorpio, asarum sieboldii, flos daturae, red halloysite, native copper, hematoxylon, mastic, myrrh, the roots of red-rooted salvia, wadalee-gum-tree, madder, giant knot weed, airpotato yam, radix angelica sinensis, radices trichosanthis, black bamboo leaves, lithospermum, rhizoma zingiberis, fructus piperis longi, morinda officinalis, hippocampus, cynomorium songaricum and eucommia ulmoides. The treatment liquid is based on the traditional Chinese medicine theory, diagnosis and treatment are based on an overall analysis of the illness and the condition of a patient, both roots and symptoms of the disease are healed, the curative rate can be obviously raised, and the total efficiency can be improved.

Description

A kind of traditional Chinese medical science directed transdermal treatment liquid for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc and preparation method thereof
Technical field
The present invention relates to a kind of take Chinese herbal medicine as traditional Chinese medicine liquid prepared by primary raw material, specifically a kind of traditional Chinese medical science directed transdermal therapeutic instrument treatment liquid being used for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc to break disease also known as Annulus Fibrosus of Lumbar Intervertebral Discs, refer to that lumbar intervertebral disc generation degeneration or External Force Acting cause Anular disruption, cause the Nucleus pulposus pressuring neural root of intervertebral disc or/and cauda equina nerve root, nerve root is under the stimulation of mechanical pressure and chemical substance, there is microcirculation and neural malnutrition, thus produce edema, hyperemia, ooze out and the inflammatory reaction such as surrounding tissue adhesion, finally cause lumbago and skelalgia, be multiplely born in waist 4 ~ 5 and waist 5 ~ sacrum 1 gap.Primary disease is many because repeatedly spraining, straining, experience the reason morbidities such as rheumatism cold-evil, and belong to the category of " lumbago ", " lumbago and skelalgia " of the traditional Chinese medical science, main pathogenesis is blockage of meridian, and QI and blood is not smooth.Prolapse of lumbar intervertebral disc great majority can be alleviated by expectant treatment, and the patient of about 80% does not need operative treatment, and especially the patient of cold-dampness numbness type prolapse of lumbar intervertebral disc 90% takes non-surgical treatment just can cure.
Non-surgical treatment conventional at present has following several: 1. completely definitely sleeping hardboard bed is had a rest, acute stage, comprises defecation and does not all leave the bed, can remove body weight, muscular strength and the extraneous load pressure to intervertebral disc like this, be the base therapy method of intervertebral disc prolapse.Patients with Acute is generally clearly better in bed 3 Zhou Houke.Now namely should start lumbodorsal muscles exercises gradually, and activity of can getting up under waistline protection.Continue after getting up to strengthen lumbodorsal muscles exercises, cancel waistline gradually, can not life-time service waistline and do not strengthen dorsal muscles and take exercise, otherwise lumbodorsal muscle atrophy will be made, more will cannot depart from waistline later.2. pelvic traction: draw the pressure that can alleviate further in intervertebral disc, curative effect is better, particularly early stage patient.3. massage: maneuver should be soft, should not be by force.4. medicine: use Western medicine dehydrant, amcinonide mainly make the nerve root edema extinction of pressurized, and reduce inflammation reaction.Western medicine conventional clinically is at present: the mannitol 250mlivdrip of 20% and dexamethasone 5 ~ 10mg, iv, but these two kinds of side effects of pharmaceutical drugs are all very large: the mannitol of 20% can cause local vascular hardening, even there is the symptoms such as red, swollen, hot, pain in local skin, cause to patient greatly painful, also all have infringement to liver, kidney, brain, nerve etc.; Mental symptom can be there is, accompanying infection etc. after dexamethasone application.
Summary of the invention
The object of this invention is to provide a kind of traditional Chinese medical science directed transdermal therapeutic instrument treatment liquid for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc and preparation method thereof.
For achieving the above object, the technical solution used in the present invention is:
Treat a traditional Chinese medical science directed transdermal treatment liquid for cold-dampness numbness type prolapse of lumbar intervertebral disc, it is characterized in that: be prepared from by the raw material of Chinese medicine of following weight proportion and Western medicine raw material:
Raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 500g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g,
Western medicine raw material: the lidocaine injection of 20%, everyone each 3ml; Alpha Vee-12, everyone each 1mg;
Above-mentioned raw materials medicine is prepared according to the following steps:
(1) by above-mentioned raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g is soaked in half an hour in the cold water exceeding powder 3 ~ 5cm, then decoct twice with boiling machine: first time decocts boils latter 20 minutes, leach decocting liquid, second time decocts boils latter 10 minutes, leaches decocting liquid, then merge twice decocting liquid and be concentrated into 1000ml, subpackage, plastic packaging is for subsequent use in the plastic bag of 100ml,
(2) used time gets 100ml reserve liquid 1 bag, pours porcelain bowl into, then add lignocaine 3ml, the Alpha Vee-12 1mg of 20%, for finally treating liquid after putting into microwave oven heating.
Prepare a method for the traditional Chinese medical science directed transdermal treatment liquid for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc, it is characterized in that: described crude drug is prepared according to the following steps:
(1) by above-mentioned raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g is soaked in half an hour in the cold water exceeding powder 3 ~ 5cm, then decoct twice with boiling machine: first time decocts boils latter 20 minutes, leach decocting liquid, second time decocts boils latter 10 minutes, leaches decocting liquid, then merge twice decocting liquid and be concentrated into 1000ml, subpackage, plastic packaging is for subsequent use in the plastic bag of 100ml,
(2) used time gets 100ml reserve liquid 1 bag, and pouring a capacity into after putting into microwave oven heating is 400ml porcelain bowl, then adds lignocaine 3ml, the Alpha Vee-12 1mg of 20%, for finally treating liquid.
Beneficial effect of the present invention:
1. many medicine comprehensive improvements, treating both the principal and secondary aspects of a disease.Medicinal liquid of the present invention is according to theory of Chinese medical science, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, adopt multi-medicament use in conjunction, the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, cold expelling dredging collateral, pain relieving granulation promoting, detumescence can be played to greatest extent, make that the waist blood circulation of pathological changes improves, adhesion release, alleviate the congested and edema of diseased region and recover its original function.And promote and adjust the immune function of body on the whole, transfer the resistance against diseases of human body inherence, adjustment body and external environment with the dynamic equilibrium of inside of human body, improve physical function on the whole, finally reach treating both the principal and secondary aspects of a disease, the object of cure diseases.
2. the use in conjunction of physics and medicine strengthens therapeutic effect.The directed transdermal therapeutic instrument of the traditional Chinese medical science produces the electronics bio wave with human body cell molecular resonance, the effective ingredient of medicinal liquid is penetrated into the deep of pathological changes by electronics bio wave, facilitate the absorption of medicinal liquid effective ingredient, strengthen the therapeutic effect of medicinal liquid, the directed transdermal therapeutic instrument of the traditional Chinese medical science has the function of heating simultaneously, medicated cushion is made to remain between optimal treatment temperature 40 DEG C ~ 45 DEG C, medicinal liquid is served to the effect of heating, the dehumidifying strengthening medicinal liquid is dispeled cold, pain relieving, antiinflammatory effect, facilitate the recovery of diseased region function.
3. Chinese medicine coordinates Western medicine application, serves the effect of Synergistic, can alleviate rapidly the pain of patient, the effect for the treatment of is doubled.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described:
Medicinal liquid of the present invention is according to theory of Chinese medical science, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, adopt multi-medicament use in conjunction, the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, cold expelling dredging collateral, pain relieving muscle-growing and detumescence can be played to greatest extent, make that the waist blood circulation of pathological changes improves, cicatrix is softening, adhesion release, alleviate the congested and edema of diseased region and recover its original function.
Embodiment
Raw material of Chinese medicine composition of the present invention:
A kind of traditional Chinese medical science directed transdermal treatment liquid for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc, it is characterized in that, by the raw material of Chinese medicine of following weight proportion and the lidocaine injection (everyone each 3ml) of Western medicine 20%, Alpha Vee-12 (everyone each 1mg) forms: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g.
Preparation technology is: by described Chinese medicine through cleaning, and the techniques such as oven dry are prepared according to the following steps under aseptic, dustless condition:
(1) by above-mentioned raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g is soaked in half an hour in the cold water exceeding powder 3 ~ 5cm, then decoct twice with boiling machine: first time decocts boils latter 20 minutes, leach decocting liquid, second time decocts boils latter 10 minutes, leaches decocting liquid, then merge twice decocting liquid and be concentrated into 1000ml, subpackage, plastic packaging is for subsequent use in the plastic bag of 100ml,
(2) used time gets reserve liquid 1 bag, and pouring a capacity into after putting into microwave oven heating is 400ml porcelain bowl, then adds lignocaine 3ml, the Alpha Vee-12 1mg of 20%, for finally treating liquid.
Using method of the present invention: each operating procedure of carrying out when the directed transdermal of the traditional Chinese medical science is treated for patient is as follows: the first step: to be all 10cm thickness by two pieces of length and widths during treatment be, and gauze pad that the hospital gauze of 6 layers makes is immersed in medicinal liquid, is cooled to 45 DEG C ~ 50 DEG C.Second step: medicinal liquid gauze is placed along lumbar spine 4 ~ 5 and waist 5 ~ sacrum 1 both sides.3rd step: by placed side by side on gauze pad along spinal column for four electrode slices of directed for traditional Chinese medical science transdermal therapeutic instrument, the top of electrode slice presses sandbag.4th step: regulating suitable treatment temperature and treatment intensity to carry out treatment 25 minutes for patient, once a day, 15 days is a course for the treatment of.
Pharmacology analysis of the present invention
In raw material of the present invention: 1. Cortex Albiziae, Radix Dipsaci, Eupolyphaga Seu Steleophaga-blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, reuniting the fractured tendons and bones; 2. Olibanum, Myrrha-promoting blood circulation and stopping pain, detumescence and promoting granulation; 3. Radix Saposhnikoviae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii-easing joint movement, reducing swelling and alleviating pain; 4. Halloysitum Rubrum, Pyritum-heat clearing away, removing dampness sore; 5. Radix Rubiae, Rhizoma Polygoni Cuspidati, Rhizoma Chuanxiong, Lignum Sappan, Radix Salviae Miltiorrhizae, Flos Carthami, Rhizoma Corydalis (processed with vinegar)-blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; 6. Ramulus Cinnamomi, Rhizoma Zingiberis, Fructus Piperis Longi-promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI, pain relieving; 7. leaf of Phyllostachys nigra (Lodd.) Munro, Rhizoma Dioscoreae Bulbiferae, catechu-removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling; 8. Rhizoma Homalomenae, Scorpio, Radix Angelicae Sinensis-bone and muscle strengthening, blood circulation promoting and dispersing pathogen accumulation, reducing swelling and alleviating pain; 9. Radix Scutellariae, Radix Trichosanthis, Radix Isatidis, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Herba Asari-heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; 10. Flos Daturae, Radix Clematidis-relieving spasm to stop pain; 11. Radix Morindae Officinaliss, Hippocampus, Herba Cynomorii, the Cortex Eucommiae-the kidney invigorating, supporing yang, bone and muscle strengthening; Lignocaine-the analgesia of 12.20%; Metabolism and the function of the neural myelin of 13. Alpha Vee-12s-safeguard.
1. blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, reuniting the fractured tendons and bones: the active factors in the Cortex Albiziae in raw material, Radix Dipsaci, Eupolyphaga Seu Steleophaga can play blood circulation promoting and blood stasis dispelling rapidly, reducing swelling and alleviating pain, the effect of reuniting the fractured tendons and bones.Modern pharmacological research shows: lignan's glucoside, saponin, flavone, volatilization wet goods effective ingredient contained in Cortex Albiziae; The effective ingredient such as triterpene soap, glycoside, iridoids, alkaloids, volatile oil contained in Radix Dipsaci; The effective ingredient such as the aminoacid in Eupolyphaga Seu Steleophaga, volatile oil, alkaloid also have good sterilization, antiviral, and accelerate damaged part metabolism, antithrombus formation, the effect of promoting blood flow, can promote that diseased region recovers normal function rapidly.
2. promoting blood circulation and stopping pain, detumescence and promoting granulation: the Olibanum in raw material, the active factors in Myrrha can play promoting blood circulation and stopping pain rapidly, the effect of detumescence and promoting granulation.Modern pharmacological research shows: these two kinds of medicines are also containing multiple antibiotics, and wherein contained resin, natural gum, volatile oil have stronger analgesic activity, can play good analgesic activity to waist.
3. easing joint movement, reducing swelling and alleviating pain: the Radix Saposhnikoviae in raw material, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii all have good heat-clearing and toxic substances removing, the effect of reducing swelling and alleviating pain.Modern pharmacological research shows: alkaloid, saponin, flavone etc. contained in medicine can promote division and the growth of neurogliocyte, by affecting the nerves endocrine function, and then regulates the physiological and pathological of body movable, to reach the effect of detumescence, easing joint movement.
4. heat clearing away, removing dampness sore: the Halloysitum Rubrum in raw material, Pyritum have good heat clearing away, the effect of removing dampness sore.Modern pharmacological research shows: active component contained in medicine, can sorption a large amount of chemistry thorn emblem thing or poisonous substance and play convergence, antiinflammatory, antipruritic and protect wound surface effect, can recover rapidly waist original function.
5. blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain: the Radix Rubiae in raw material, Rhizoma Polygoni Cuspidati, Rhizoma Chuanxiong, Lignum Sappan, Radix Salviae Miltiorrhizae, Flos Carthami, Rhizoma Corydalis (processed with vinegar) have blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain.Modern pharmacological research shows: triterpenes, saponin, aminoacid, flavone, sugar and multiple inorganic elements contained in medicine, have the effects such as resisting fatigue, anti-hypoxia, immunomodulating, treatment carbuncle sore.
6. promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI, analgesia, antiinflammatory, hemostasis: the Ramulus Cinnamomi in raw material, Rhizoma Zingiberis, Fructus Piperis Longi all have promoting the flow of QI-blood by warming the meridian, the effect of activating YANG and prormoting functioning of QI.Modern pharmacological research shows: cinnamic aldehyde contained in medicine, ketone, alkene constituents, alkaloids, volatile oil have very strong analgesia, and antiinflammatory waits effect.
7. removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling: the leaf of Phyllostachys nigra (Lodd.) Munro in raw material, Rhizoma Dioscoreae Bulbiferae, catechu have very strong removing toxic substances and promoting subsidence of swelling, the effect of blood circulation promoting and blood stasis dispelling.Modern pharmacological research shows: alkaloid contained in medicine, non-alkaloid and kind more than 20 have calmness, spasmolytic, immunomodulating, anti-radiation, antineoplastic effective composition.
8. blood circulation promoting and dispersing pathogen accumulation, detumescence relieving convulsion, bitterly: the Rhizoma Homalomenae in raw material, Scorpio, Radix Angelicae Sinensis can effectively be invigorated blood circulation, eliminating stagnation, detumescence relieving convulsion, pain relieving.Modern pharmacological research shows: volatile oil contained in medicine Rhizoma Homalomenae has significantly suppression Brucella growth, controls the effect of podomere ache, and the scorpion venom in Scorpio has detumescence relieving convulsion, analgesic effect; Radix Angelicae Sinensis volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia; Radix Angelicae Sinensis has antiinflammatory to various pathogens, also has the function of Promote immunity.
9. heat-clearing and toxic substances removing, dispersing swelling and dissipating binds: the multiple alkaloid that the Radix Scutellariae in raw material, Radix Trichosanthis, Radix Isatidis, Fructus Forsythiae, Radix Arnebiae (Radix Lithospermi), Herba Asari contain, volatile oil has very strong heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds; The compositions such as trichosanthin, decanoylacetaldehyde, capraldehyde, lauryl aldehyde and methyl nonyl ketone have very strong heat-clearing and toxic substances removing, the effect of detumescence and apocenosis.
10. relieving spasm to stop pain: the Flos Daturae in raw material, the effective ingredient of Radix Clematidis have the effect of relieving spasm to stop pain, modern pharmacological research shows: the alkaloid in Flos Daturae has anesthesia to diseased region, spasmolytic, analgesic acts on, Radix Clematidis is the key medicine for the treatment of arthralgia pain contracture numbness, and the compositions such as contained protoanemonin, sugared Saponin also have the effect of anti-inflammation.
11. the kidney invigorating, supporing yang, bone and muscle strengthening: the Radix Morindae Officinalis in raw material, Hippocampus, Herba Cynomorii, the Cortex Eucommiae have the effect of the kidney invigorating, supporing yang, bone and muscle strengthening.Modern pharmacological research shows: containing effective ingredient such as saccharide, Anthraquinones, Coumarins, aminoacid, protein, organic acid, flavonoid, volatile oil, steroidal, phenols in Radix Morindae Officinalis, the steroid compound contained in Hippocampus, the effective ingredient such as the triterpenes contained in Herba Cynomorii, steroid all have reducing swelling and alleviating pain, the immunity of enhancing body, antidotal effect.The effective ingredient such as the multiple proteins in the Cortex Eucommiae, vitamin and mineral have the multiple pharmacological effect such as enhancing immunity, blood pressure lowering, antiinflammatory, antiviral, anti-stress, muscle reinforcing and bone strengthening, defying age, antioxidation.
12. analgesias: the lidocaine injection of 20% in raw material can play good analgesic activity, the sleep being conducive to patient promotes the recovery of disease.
The metabolism of the neural myelin of 13. maintenance and function: the Alpha Vee-12 in raw material can safeguard metabolism and the function of neural myelin, promotes the reparation of injured nerve root.
Pharmacodynamics statistics of the present invention:
1. general clinical data: choose and move in my institute's acupuncture two section the same period, is diagnosed as cold-dampness numbness type prolapse of lumbar intervertebral disc and does not need the patient 216 of operative treatment routine through nuclear magnetic resonance check, being divided into two groups at random; Treatment group 108 example, man 45 example, female 63 example; 21.48 ~ 79.42 years old age, average 59.32 years old; Matched group 108 example, man 48 example, female 60 example, 23.72 ~ 83.34 years old age, average 57.82 years old; These two random group patients compare in sex, age, nutriture etc., no significant difference (P > 0.05).
2. Therapeutic Method: the Therapeutic Method a. that treatment group patient adopts gives pelvic traction: allow patient crouch on Electronic control extension table, breastbone and pelvis are fixed with special ligature respectively, carry out traction 1 hour with the pull strength exceeding body weight 10Kg.Impression according to patient alleviates pull strength in time, makes patient's not only comfortable but also safety.Every traction in 5 days once, after traction, advise patient's absolute bed rest, draw 3 times altogether.B. massage, acupuncture once a day, within 15 days, be a course for the treatment of.C. give mannitol 250mlivdrip and dexamethasone 5mg, the iv of 20%, once a day, reduce the consumption of dexamethasone gradually according to the state of an illness of patient, until the mannitol of inactive 20% and dexamethasone.D. the treatment of the traditional Chinese medical science directed transdermal therapeutic instrument treatment liquid is given.Once a day, within 15 days, be a course for the treatment of.
Matched group patient gives a. and gives pelvic traction: allow patient crouch on Electronic control extension table, breastbone and pelvis are fixed with special ligature respectively, carry out traction 1 hour with the pull strength exceeding body weight 10Kg.Impression according to patient alleviates pull strength in time, makes patient's not only comfortable but also safety.Every traction in 5 days once, after traction, advise patient's absolute bed rest, draw 3 times altogether.B. massage, acupuncture once a day, within 15 days, be a course for the treatment of.C. give mannitol 250mlivdrip and dexamethasone 5mg, the iv of 20%, once a day, reduce the consumption of dexamethasone gradually according to the state of an illness of patient, until the mannitol of inactive 20% and dexamethasone.
3. evaluation index: criterion of therapeutical effect is according to the Lumbar Intervertebral Disc standard of State Administration of Traditional Chinese Medicine's " Chinese medical disease diagnosis and treatment standard ": cure: lumbago and skelalgia disappears, straight-leg raising test more than 70 ° can extensive recovery operation; Effective: lumbago and skelalgia alleviates, waist movable function improves; Invalid: symptom and sign are without improvement.
4. statistical method: application SPSS13.0 statistical analysis software carries out data analysis, between two groups, comparitive study adopts x2 inspection, and measurement data adopts t inspection, and p ﹤ 0.05 has statistical significance for difference.
Table 1: two groups of patient outcomes compare [example (%)] after a course for the treatment of
Note: compare χ 2=11.44p<0.05 there were significant differences with matched group
Table 2: two groups of patients use the mannitol of 20% and the comparison (± s) of dexamethasone natural law
Note: there were significant differences to compare p<0.05 with matched group
5. conclusion: two groups of patient outcomes compare after two courses for the treatment of, treatment group is apparently higher than matched group as shown in Table 1, treatment group uses the mannitol of 20% and the natural law of dexamethasone to be obviously less than matched group as shown in Table 2, and difference has statistical significance (P < 0.05).Medicinal liquid of the present invention is according to theory of Chinese medical science, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, significantly can improve the cure rate of patient with effectively total, the application mannitol of 20% and the natural law of dexamethasone obviously reduce, and reduce these two kinds of medicines to the infringement of human body.

Claims (2)

1. treat a traditional Chinese medical science directed transdermal treatment liquid for cold-dampness numbness type prolapse of lumbar intervertebral disc, it is characterized in that: be prepared from by the raw material of Chinese medicine of following weight proportion and Western medicine raw material:
Raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 500g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g,
Western medicine raw material: the lidocaine injection of 20%, everyone each 3ml; Alpha Vee-12, everyone each 1mg;
Above-mentioned raw materials medicine is prepared according to the following steps:
(1) by above-mentioned raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g is soaked in half an hour in the cold water exceeding powder 3 ~ 5cm, then decoct twice with boiling machine: first time decocts boils latter 20 minutes, leach decocting liquid, second time decocts boils latter 10 minutes, leaches decocting liquid, then merge twice decocting liquid and be concentrated into 1000ml, subpackage, plastic packaging is for subsequent use in the plastic bag of 100ml,
(2) used time gets 100ml reserve liquid 1 bag, pours porcelain bowl into, then add lignocaine 3ml, the Alpha Vee-12 1mg of 20%, for finally treating liquid after putting into microwave oven heating.
2. prepare a method for the traditional Chinese medical science for the treatment of cold-dampness numbness type prolapse of lumbar intervertebral disc described in claim 1 directed transdermal treatment liquid, it is characterized in that: described crude drug is prepared according to the following steps:
(1) by above-mentioned raw material of Chinese medicine: Eupolyphaga Seu Steleophaga 100g, Radix Angelicae Pubescentis 100g, Radix Dipsaci 100g, Rhizoma Et Radix Notopterygii 150g, Rhizoma Chuanxiong 100g, Flos Carthami 100g, Radix Saposhnikoviae 100g, Cortex Albiziae 100g, Fructus Forsythiae 120g, Radix Scutellariae 50g, Radix Isatidis 50g, Rhizoma Homalomenae 50g, Radix Clematidis 50g, Ramulus Cinnamomi 50g, Rhizoma Corydalis (processed with vinegar) 50g, Scorpio 50g, Herba Asari 30g, Flos Daturae 2g, Halloysitum Rubrum 100g, Pyritum 30g, Lignum Sappan 50g, Olibanum 50g, Myrrha 50g, Radix Salviae Miltiorrhizae 50g, catechu 50g, Radix Rubiae 50g, Rhizoma Polygoni Cuspidati 50g, Rhizoma Dioscoreae Bulbiferae 50g, Radix Angelicae Sinensis 50g, Radix Trichosanthis 100g, leaf of Phyllostachys nigra (Lodd.) Munro 150g, Radix Arnebiae (Radix Lithospermi) 50g, Rhizoma Zingiberis 50g, Fructus Piperis Longi 20g, Radix Morindae Officinalis 50g, Hippocampus 50g, Herba Cynomorii 50g, Cortex Eucommiae 50g is soaked in half an hour in the cold water exceeding powder 3 ~ 5cm, then decoct twice with boiling machine: first time decocts boils latter 20 minutes, leach decocting liquid, second time decocts boils latter 10 minutes, leaches decocting liquid, then merge twice decocting liquid and be concentrated into 1000ml, subpackage, plastic packaging is for subsequent use in the plastic bag of 100ml,
(2) used time gets 100ml reserve liquid 1 bag, and pouring a capacity into after putting into microwave oven heating is 400ml porcelain bowl, then adds lignocaine 3ml, the Alpha Vee-12 1mg of 20%, for finally treating liquid.
CN201610072259.6A 2016-02-02 2016-02-02 Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof Pending CN105435210A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610072259.6A CN105435210A (en) 2016-02-02 2016-02-02 Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610072259.6A CN105435210A (en) 2016-02-02 2016-02-02 Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105435210A true CN105435210A (en) 2016-03-30

Family

ID=55546133

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610072259.6A Pending CN105435210A (en) 2016-02-02 2016-02-02 Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105435210A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107349382A (en) * 2016-05-09 2017-11-17 张开建 It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof
CN107397894A (en) * 2016-05-18 2017-11-28 张开建 A kind of ointment for treating acute lumbar muscle sprain and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435815A (en) * 2014-11-12 2015-03-25 张景悦 Externally-applied traditional Chinese medicine for treating adhesive capsulitis of shoulders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435815A (en) * 2014-11-12 2015-03-25 张景悦 Externally-applied traditional Chinese medicine for treating adhesive capsulitis of shoulders

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
安军明等: "《方云鹏临证精华》", 31 March 2015, 陕西科学技术出版社 *
戴慎: "《中医病证诊疗标准与方剂选用》", 30 November 2001, 人民卫生出版社 *
潘月丽 等: "《实用中医小方》", 30 April 2008, 中医古籍出版社 *
郭彦涛 等: "辨证分型定向透药治疗腰椎间盘突出症的疗效和安全性研究", 《深圳中西医结合杂志》 *
陈祥塔: "《运动创伤学》", 31 March 2007, 江西高校出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107349382A (en) * 2016-05-09 2017-11-17 张开建 It is a kind of treat ankylosing spondylitis superintend and direct moxibustion powder and preparation method thereof
CN107397894A (en) * 2016-05-18 2017-11-28 张开建 A kind of ointment for treating acute lumbar muscle sprain and preparation method thereof

Similar Documents

Publication Publication Date Title
CN103356877A (en) Traditional Chinese medicine composition for treating orthopedic diseases
CN105288230A (en) Traditional Chinese medicine composition for treating paralysis
CN103263591A (en) External-use medicine for treating neck/lumbar disc herniation and osteoarthropathy
CN102119990A (en) Chinese medicinal preparation for nourishing liver and kidney, supplementing qi, engendering blood, promoting blood circulation, removing obstruction in channels and relieving pain
CN105435210A (en) Traditional Chinese medicine oriented permeable drug treatment liquid for treating cold-dampness stasis type lumbar disc herniation and preparation method thereof
CN103446360B (en) Traditional Chinese medicine capsule preparation for treating lumbar disc herniation and preparation method of traditional Chinese medicine capsule preparation
CN104922363A (en) Traditional Chinese medicine composite for treating osteoproliferation
CN100388931C (en) Medicine for treating pelvic inflammation and preparation method thereof
CN112972557A (en) Medicinal liquor for treating arthralgia and myalgia and preparation method thereof
CN101632831B (en) Traditional Chinese medicine medicated wine for treating waist and leg pains
CN105560736A (en) Traditional Chinese medicine composition for treating herpes zoster
CN104644928A (en) Medicine for treating cervical and lumbar disc herniations
CN104740003A (en) Traditional Chinese medicine for treating lumbar disc herniation
CN101954043A (en) Medicament for treating hyperosteogeny and preparation method thereof
CN102366591B (en) Chinese herbal medicinal wine for treating rheumatoid and rheumatoid arthritis and its preparation method
CN101637535B (en) Medicine for treating bone hyperplasia and preparation method thereof
CN101983712A (en) Novel medicament for treating coronary heart disease
CN104840814A (en) Traditional Chinese medicine combination for treating senile femoral head necrosis
CN104623506A (en) Traditional Chinese medicine for treating infertility gynaecopathia
CN105687542A (en) Chinese herbal preparation for fracture aftertreatment and preparing method thereof
CN105169329A (en) Abdominal pain relieving navel plaster for children and preparation method of navel plaster
CN105031073A (en) Ointment for promoting blood circulation to remove blood stasis and preparation method of ointment
CN1183918C (en) Medicine for curing protrution of intervetebral disc and its preparing method
CN104587256A (en) Traditional Chinese medicine composition for treating prostatitis
CN103110719B (en) Traditional Chinese medicine wine for treating kidney deficiency and essence depletion type osteoporosis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160330

WD01 Invention patent application deemed withdrawn after publication