CN105031073A - Ointment for promoting blood circulation to remove blood stasis and preparation method of ointment - Google Patents
Ointment for promoting blood circulation to remove blood stasis and preparation method of ointment Download PDFInfo
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- CN105031073A CN105031073A CN201510522762.2A CN201510522762A CN105031073A CN 105031073 A CN105031073 A CN 105031073A CN 201510522762 A CN201510522762 A CN 201510522762A CN 105031073 A CN105031073 A CN 105031073A
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Abstract
The invention discloses an ointment for promoting blood circulation to remove blood stasis and a preparation method of the ointment. The ointment is mainly prepared from the following raw medicines in parts by weight: 10-14 parts of dodder, 7-13 parts of tall monkshood root, 9-12 parts of zinnia, 8-13 parts of boneset, 6-12 parts of passiflora, 8-14 parts of mistletoe, 6-12 parts of cantonese ampelopsis, 9-15 parts of lacca, 6-13 parts of ephedra, 12-16 parts of Chinese rose, 8-15 parts of walnut kernel, 6-14 parts of saussurea cordifolia, 9-14 parts of Impatiens aquatillis Hook. f. and 7-15 parts of siberian walking fern. The main components of the product prepared by the preparation method disclosed by the invention are obtained through extraction of traditional Chinese medicine plants, so that the product is safe in use and free of any toxic or side effect. The ointment disclosed by the invention is good in curative effect, low in cost, economical and practical, and worthy of being clinically popularized.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of blood circulation promoting and blood stasis dispelling unguentum and preparation method.
Background technology
Prolapse of lumbar intervertebral disc has another name called prolapse of lumbar intervertebral disc, it is a kind of disease more common on Orthopedic Clinical, mainly because vertebral pulp, fibrous ring and cartilaginous lamina, especially after there is degenerative change in various degree in the lumbar intervertebral disc each several part such as vertebral pulp, under the effect of external force factor, the Anular disruption of intervertebral disc, nucleus pulposus is given prominence to from part of breaking or emerges in rear or intraspinal tube, adjacent ridge nerve root is caused to be stimulated or oppress, thus cause flank pain, there is a series of clinical symptoms such as numbness, pain in side lower limb or bilateral lower limb.Classical symptom has lumbago, electric shock sample severe pain, instability of gait, nerve root excitation symptom, degeneration of intervertebral disc, toe numb.Prolapse of lumbar intervertebral disc is the highest with waist 4-5, waist 5-sacrum 1 sickness rate, accounts for 95%.Clinical treatment many employings traction therapeutic, physiotherapy (shortwave, ultrashort wave therapy; Diadynamic current therapy is entire; Ultrastimulating current therapy), Western-style manipulation etc.
Publication No. CN102961610A(application number 201210518969.9) Chinese patent literature disclose a kind of Topical paste patch, by the Radix Angelicae Sinensis of specific proportioning, Poria, Radix Scutellariae, Radix Paeoniae Rubra, Radix Astragali, Radix Achyranthis Bidentatae, Rhizoma Coptidis, eupolyphaga, Rhizoma Corydalis, Radix Saposhnikoviae, Scorpio, Flos Carthami, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Periostracum Serpentis, Olibanum, Myrrha, Camphora, Herba Schizonepetae, Radix Codonopsis, Radix Rehmanniae Preparata, Periostracum Cicadae, Radix Dipsaci, Caulis Spatholobi, Semen Persicae, Catechu, Semen Strychni, Radix Aucklandiae (Radix Vladimiriae), Radix Bupleuri, Fructus Crotonis, Radix Paeoniae Alba, Semen Momordicae, Rhizoma Polygoni Cuspidati, Rhizoma Gastrodiae, Plumbum preparatium, Flos Lonicerae, the Cortex Eucommiae, the Radix Euphorbiae Pekinensis, Lithargyrum, Oleum Sesami is made by conventional method.Publication No. CN102626491A(application number 201210120821.X) Chinese patent literature disclose treatment prolapse of lumbar intervertebral disc Chinese herbal medicine for external use compositions, be made up of the following raw materials according of weight proportion, Herba Eleusines Indicae 30, Herba Taraxaci 30, Radix Gentianae Macrophyllae 20, Ramulus Cinnamomi 25, Xian Elata Pin root bark 40, Radix Angelicae Sinensis 20, Herba Lycopodii 30, Rhizoma Et Radix Notopterygii 15, Radix Angelicae Pubescentis 30, Radix Paeoniae Rubra 30, Radix Clematidis 30, five cuticle 25, Rhizoma Chuanxiong 30, the Radix Aucklandiae 20, Olibanum 30, Myrrha 25.Publication No. CN104189808A(application number 201410405753.0) Chinese patent literature disclose treatment prolapse of lumbar intervertebral disc exterior-applied medical wine, consist of Radix Salviae Miltiorrhizae, Sanguis Draxonis, Flos Carthami, Radix Notoginseng, Radix Aconiti, Rhizoma Zingiberis, Borneolum Syntheticum, the Cortex Eucommiae, Olibanum, Myrrha, Chinese liquor.
People's many trust tcm therapy treats this disease, and the traditional Chinese medical science formula for the treatment of this disease has many, but major part more or less all exists a little shortcoming, therefore, has needs to develop a kind of good effect, externally used paste easy to use.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of determined curative effect, safe and reliable blood circulation promoting and blood stasis dispelling unguentum and preparation method.
Technical scheme of the present invention is:
A kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from primarily of following bulk drugs, is mass parts: Semen Cuscutae 10-14, Radix aconiti sinomontani 7-13, youth-and-old-age 9-12, Herba Lycopi 8-13, Herba Passiflorae Caeruleae 6-12, Herba Taxilli 8-14, Radix Ampelopsis Cantoniensis 6-12, Lacca 9-15, Herba Ephedrae 6-13, Flos Rosae Chinensis 12-16, Semen Juglandis 8-15, Saussurea cordifolia 6-14, water Impatientis 9-14, Herba Camptosori Sibirici 7-15.
In preferred scheme, Semen Cuscutae 11-13, Radix aconiti sinomontani 9-11, youth-and-old-age 10-11, Herba Lycopi 9-12, Herba Passiflorae Caeruleae 8-10, Herba Taxilli 10-12, Radix Ampelopsis Cantoniensis 8-10, Lacca 10-14, Herba Ephedrae 8-11, Flos Rosae Chinensis 13-15, Semen Juglandis 10-13, Saussurea cordifolia 8-12, water Impatientis 10-13, Herba Camptosori Sibirici 9-13.
Be more preferably, Semen Cuscutae 12, Radix aconiti sinomontani 10, youth-and-old-age 10.5, Herba Lycopi 10.5, Herba Passiflorae Caeruleae 9, Herba Taxilli 11, Radix Ampelopsis Cantoniensis 9, Lacca 12, Herba Ephedrae 9.5, Flos Rosae Chinensis 14, Semen Juglandis 11.5, Saussurea cordifolia 10, water Impatientis 11.5, Herba Camptosori Sibirici 11.
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, step is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel is mixed thoroughly (mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine slightly to soak, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 40-100 mesh sieve (preferably, pulverized 60-80 mesh sieve with step (1) (2) made crude drug; Be more preferably, pulverized 70 mesh sieves);
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, with reflux, extract, 1-2 hour (preferred, reflux, extract, 1.5 hours) at 95% ethanol 80 DEG C, sucking filtration, filtering residue is reflux, extract, again, merge extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, decoct with water, 30-45 minute is boiled in big fire, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, the total amount of step (1) yellow wine and Mel is the 0.8-1.5 of Radix aconiti sinomontani quality doubly (preferred, the total amount of yellow wine and Mel is 1.2 times of Radix aconiti sinomontani quality).
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, step (3) is slightly soaked and (preferably, is slightly soaked 18-25 minute in 15-28 minute; Be more preferably, slightly soak 21 minutes).
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, the 5-7 that the amount of step (4) 95% ethanol is institute's lixiviate crude drug quality is (preferred, 6 times that the amount of 95% ethanol is institute's lixiviate crude drug quality) doubly.
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, step (5) amount of water is the 6-7 of total raw material medicine quality doubly (preferred, amount of water is 6.5 times of total raw material medicine quality).
The preparation method of described a kind of blood circulation promoting and blood stasis dispelling unguentum, step (5) big fire is boiled 35-40 minute (preferred, big fire boils 37.5 minutes).
Present invention also offers the application of described a kind of blood circulation promoting and blood stasis dispelling unguentum when preparing the medicine for the treatment of prolapse of lumbar intervertebral disc.
A kind of blood circulation promoting and blood stasis dispelling unguentum provided by the invention is prepared from meticulously, easy to use, and through affected part, alleviates lumbago and skelalgia symptom.In addition, excellent results of the present invention also shows:
1, main component of the present invention is extracted by Chinese medicinal plant and is obtained, and use safety is without any side effects;
2, this prescription has the effect such as promoting blood circulation and stopping pain, expelling wind and removing dampness, can promote tissue repair, recovers function of nervous system;
3, good effect of the present invention, cost is low, economical and practical, and clinic is promoted.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1a kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Cuscutae 10 parts, Radix aconiti sinomontani 7 parts, youth-and-old-age 9 parts, Herba Lycopi 8 parts, Herba Passiflorae Caeruleae 6 parts, Herba Taxilli 8 parts, Radix Ampelopsis Cantoniensis 6 parts, Lacca 9 parts, 6 parts, Herba Ephedrae, Flos Rosae Chinensis 12 parts, Semen Juglandis 8 parts, Saussurea cordifolia 6 parts, water Impatientis 9 parts, Herba Camptosori Sibirici 7 parts.
The preparation method of above-mentioned a kind of blood circulation promoting and blood stasis dispelling unguentum is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel mixes that (total amount of yellow wine and Mel is 0.8 times of Radix aconiti sinomontani quality thoroughly, wherein the mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine and slightly soak 15 minutes, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 40 mesh sieves with step (1) (2) made crude drug;
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, by reflux, extract, at 95% ethanol 80 DEG C of institute's lixiviate crude drug quality 5 times 1 hour, sucking filtration, filtering residue is reflux, extract, again, merges extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, add up the soak by water of 6 times of crude drug quality, big fire boils 30 minutes, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
embodiment 2a kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Cuscutae 14 parts, Radix aconiti sinomontani 13 parts, youth-and-old-age 12 parts, Herba Lycopi 13 parts, Herba Passiflorae Caeruleae 12 parts, Herba Taxilli 14 parts, Radix Ampelopsis Cantoniensis 12 parts, Lacca 15 parts, 13 parts, Herba Ephedrae, Flos Rosae Chinensis 16 parts, Semen Juglandis 15 parts, Saussurea cordifolia 14 parts, water Impatientis 14 parts, Herba Camptosori Sibirici 15 parts.
A kind of preparation method of blood circulation promoting and blood stasis dispelling unguentum is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel mixes that (total amount of yellow wine and Mel is 1.5 times of Radix aconiti sinomontani quality thoroughly, wherein the mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine and slightly soak 28 minutes, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 100 mesh sieves with step (1) (2) made crude drug;
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, by reflux, extract, at 95% ethanol 80 DEG C of institute's lixiviate crude drug quality 7 times 2 hours, sucking filtration, filtering residue is reflux, extract, again, merges extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, add up the soak by water of 7 times of crude drug quality, big fire boils 45 minutes, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
Model case: xxx, man, 38 years old.Main suit: suffer from prolapse of lumbar intervertebral disc 10 months, once turned round waist, examination in hospital L because moving accidentally
4 ~ 5intercalated disc is given prominence to, and obviously alleviates through treatment symptom, but is always and fails recovery from illness, and recently because of tired and aggravation, the twinge of waist radioactivity, involves lower limb, right lower extremity radiated pain, and light night in daytime is heavy, and lower limb feel cold.
Use a kind of blood circulation promoting and blood stasis dispelling unguentum of the present embodiment gained upon somebody's introduction, twice daily, squeeze at the palm of the hand by ointment at every turn, two handss merge stranding and open, along affected part by gently gradually weighing, and repeated massage from top to bottom, penetration enhancement, 15 days courses for the treatment of.After using a course for the treatment of, lumbago and skelalgia obviously alleviates, but limitation of activity, after using two courses for the treatment of, lumbago and skelalgia is eliminated substantially, and straight lower limb can raise 65 °, and continue a course for the treatment of of use, patient's lumbago and skelalgia disappears completely, straight lower limb can raise 76 °, freedom of movement, and patient fully recovers, and follows up a case by regular visits to and do not recur in 1 year.
embodiment 3a kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Cuscutae 11 parts, Radix aconiti sinomontani 9 parts, youth-and-old-age 10 parts, Herba Lycopi 9 parts, Herba Passiflorae Caeruleae 8 parts, Herba Taxilli 10 parts, Radix Ampelopsis Cantoniensis 8 parts, Lacca 10 parts, 8 parts, Herba Ephedrae, Flos Rosae Chinensis 13 parts, Semen Juglandis 10 parts, Saussurea cordifolia 8 parts, water Impatientis 10 parts, Herba Camptosori Sibirici 9 parts.
A kind of preparation method of blood circulation promoting and blood stasis dispelling unguentum is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel mixes that (total amount of yellow wine and Mel is 0.8 times of Radix aconiti sinomontani quality thoroughly, wherein the mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine and slightly soak 18 minutes, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 60 mesh sieves with step (1) (2) made crude drug;
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, by reflux, extract, at 95% ethanol 80 DEG C of institute's lixiviate crude drug quality 5 times 1 hour, sucking filtration, filtering residue is reflux, extract, again, merges extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, add up the soak by water of 6 times of crude drug quality, big fire boils 35 minutes, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
Model case: xxx, female, 56 years old.Before 2 years, because of lumbago companion lower-left acroesthesia medical check, diagnose out L
4 ~ 5and L
5s
1intervertebral disk hernia, posterior longitudinal ligament and ligamenta flava thicken, and apply acupuncture and traction therapeutic, symptom is eliminated substantially, but nearly one month, waist and lower limb pain showed effect again, on rear side of waist and left leg, shock by electricity sample bitterly, instability of gait, limitation of activity, examination in hospital, prolapse of lumbar intervertebral disc recurs.
Use a kind of blood circulation promoting and blood stasis dispelling unguentum of the present embodiment gained, twice daily, squeeze at the palm of the hand by ointment at every turn, two handss merge stranding and open, along affected part by gently gradually weighing, and repeated massage from top to bottom, penetration enhancement, 15 days courses for the treatment of.After using a course for the treatment of, lumbago and skelalgia obviously alleviates, and waist lower limb movable function improves, after using two courses for the treatment of, gait is steady, and lumbago and skelalgia is eliminated substantially, and leg raising straight can reach 55 °, after using the 3rd course for the treatment of, the all diseases of patient disappear entirely, and leg raising straight can reach 70 °, can autonomic activities, patient cures substantially, follows up a case by regular visits to the state of an illness without repeatedly in 1 year.
embodiment 4a kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Cuscutae 13 parts, Radix aconiti sinomontani 11 parts, youth-and-old-age 11 parts, Herba Lycopi 12 parts, Herba Passiflorae Caeruleae 10 parts, Herba Taxilli 12 parts, Radix Ampelopsis Cantoniensis 10 parts, Lacca 14 parts, 11 parts, Herba Ephedrae, Flos Rosae Chinensis 15 parts, Semen Juglandis 13 parts, Saussurea cordifolia 12 parts, water Impatientis 13 parts, Herba Camptosori Sibirici 13 parts.
A kind of preparation method of blood circulation promoting and blood stasis dispelling unguentum is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel mixes that (total amount of yellow wine and Mel is 1.5 times of Radix aconiti sinomontani quality thoroughly, wherein the mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine and slightly soak 25 minutes, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 80 mesh sieves with step (1) (2) made crude drug;
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, by reflux, extract, at 95% ethanol 80 DEG C of institute's lixiviate crude drug quality 7 times 2 hours, sucking filtration, filtering residue is reflux, extract, again, merges extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, add up the soak by water of 7 times of crude drug quality, big fire boils 40 minutes, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
embodiment 5a kind of blood circulation promoting and blood stasis dispelling unguentum, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Cuscutae 12 parts, Radix aconiti sinomontani 10 parts, youth-and-old-age 10.5 parts, Herba Lycopi 10.5 parts, Herba Passiflorae Caeruleae 9 parts, Herba Taxilli 11 parts, Radix Ampelopsis Cantoniensis 9 parts, Lacca 12 parts, 9.5 parts, Herba Ephedrae, Flos Rosae Chinensis 14 parts, Semen Juglandis 11.5 parts, Saussurea cordifolia 10 parts, water Impatientis 11.5 parts, Herba Camptosori Sibirici 11 parts.
A kind of preparation method of blood circulation promoting and blood stasis dispelling unguentum is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel mixes that (total amount of yellow wine and Mel is 1.2 times of Radix aconiti sinomontani quality thoroughly, wherein the mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine and slightly soak 21 minutes, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 70 mesh sieves with step (1) (2) made crude drug;
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, by reflux, extract, at 95% ethanol 80 DEG C of institute's lixiviate crude drug quality 6 times 1.5 hours, sucking filtration, filtering residue is reflux, extract, again, merges extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, add up the soak by water of 6.5 times of crude drug quality, big fire boils 37.5 minutes, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Semen Cuscutae: base is former: be the seed of convolvulus cuscuta plant or cuscuta japonica Choisy.Nature and flavor: sweet, temperature.Gui Jing: return liver,kidney,spleen warp.Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down, externally treating leucoderma.
Radix aconiti sinomontani: base is former: be the root of ranunculaceae plant Aconitum sinomontanum Nakai.Nature and flavor: bitter, pungent, salty, temperature.Poisonous.Function cures mainly: expelling wind and removing dampness, eliminating stasis to stop pain.For lumbago, skelalgia of rheumatism, peratodynia, traumatic injury.
Youth-and-old-age: base is former: be the herb of feverfew Herba Zinnia elegansae.Nature and flavor: bitter in the mouth, pungent, cool in nature.Function cures mainly: heat clearing away, dampness removing, removing toxic substances.Main hygropyretic dysentery, stranguria, acute mastitis, furuncle and phyma.
Herba Lycopi: base is former: be the stem and leaf of labiate lycopus lucidus.Nature and flavor: bitter, pungent, tepor.Gui Jing: return liver, spleen channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, edema.
Herba Passiflorae Caeruleae: base is former: be the herb of Passifloraceae plant Herba Passiflorae Caeruleae.Nature and flavor: bitter in the mouth, warm in nature.Function cures mainly: except wind, and dehumidifying, invigorates blood circulation, pain relieving.Main headache due to common cold, nasal obstruction watery nasal discharge, rheumatic arthritis, dysmenorrhea, neuralgia, loses eye, dysentery, fracture.
Herba Taxilli: base is former: be the branch and leaf of Loranthaceae plant Herba Visci, Herba Taxilli or loranthus yadoriki etc.Nature and flavor: bitter, sweet, flat.Gui Jing: return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement, hypertension.
Radix Ampelopsis Cantoniensis: base is former: be root or the Herb of vitaceae ampelopsis cantoniensis.Nature and flavor: pungent are bitter, cool.Gui Jing: the heart, spleen channel.Function cures mainly: removing dampness of dispeling the wind, heat-clearing and toxic substances removing.Main summer catches a cold, rheumatic arthralgia, swollen ulcer drug, eczema eczema
Lacca: base is former: be the colloid that Lacciferidae insecticide lac insect is secreted on branch.Nature and flavor: bitter, cold.Function cures mainly: heat clearing away, removing heat from blood, removing toxic substances.Not saturating for macule, sore swollen toxin.
Herba Ephedrae: base is former: be the herb stem of Ephedraceae plant plait Herba Ephedrae, ephedra equisetina or epheday intermedia.Nature and flavor: pungent, micro-hardship, temperature.Gui Jing: return lung, urinary bladder channel.Function cures mainly: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema, bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.
Flos Rosae Chinensis: base is former: for the half-open of rosaceous plant Flos Rosae Chinensis is let off fireworks.Nature and flavor: sweet, temperature.Gui Jing: return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, loose poison detumescence.For menoxenia, dysmenorrhea, carbuncle furuncle and phyma poison, tuberculous lymphadenitis (non-diabrosis).
Semen Juglandis: base is former: be the seed of juglandaceae plant Semen Juglandis.Nature and flavor: sweet, temperature.Gui Jing: return kidney, lung, large intestine channel.Function cures mainly: the kidney invigorating, warming the lung, intestine moistening.For soreness of the waist and knees, impotence and seminal emission, deficiency and coldness is breathed heavily and is coughed, constipation.
Saussurea cordifolia: base is former: be the root of Compositae Genus Saussurea plant Saussurea cordifolia.Nature and flavor: temperature, pungent.Function cures mainly: cold expelling, analgesia.Control arthralgia, impairment caused by overstrain, aversion to cold is had a headache.
Water Impatientis: base is former: be the herb of Balsaminaceae plant Herba Impatientis Chinensis flower.Nature and flavor: bitter in the mouth, Xin Xingping.Function cures mainly: heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, eliminating carbuncle of drawing out the pus.Main infantile pneumonia, laryngopharynx swelling and pain, hematodiarrhoea, snake head-like infection, carbuncle pyogenic infections from tumour or sore, lung is tied.
Herba Camptosori Sibirici: base is former: be the herb of Aspleniaceae plant walking fern.Nature and flavor: light are flat.Function cures mainly: hemostasis, antiinflammatory.Control traumatic hemorrhage, metrorrhagia.
test example 1the clinical practice of a kind of blood circulation promoting and blood stasis dispelling unguentum (embodiment 5) of gained of the present invention:
In October ,-2013 in March, 2012, in the prolapse of lumbar intervertebral disc patient that the orthopedics department outpatient service of 5 hospitals is accepted for medical treatment, filter out 283 examples, wherein women 136 example, male 147 example, age 31-66 year, the mean age (42.7 ± 5.3) year, the course of disease 6 months-5 years, average 18 months.Wherein outstanding position L
4 ~ 5197 examples, L
5s
186 examples.Diagnostic criteria: 1, skelalgia overweights lumbago, and in typical sciatic nerve areal area pain, or with numbness; 2, straight-leg raising test positive and in the wrong ankle reinforcement test is positive, and neck sign is positive; 3, there is amyotrophy, in unable, the hyporeflexia of moving, four kinds of neurosignses such as feel to go down two kinds; 4, support that the impact of clinical symptoms and sign changes.
Patient is divided into two groups at random, experimental group 188 example and matched group 95 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group uses products obtained therefrom of the present invention, twice daily, squeezes at the palm of the hand by ointment at every turn, and two handss merge stranding and open, and along affected part by gently gradually weighing, repeated massage from top to bottom, penetration enhancement, 15 days courses for the treatment of, uses three courses for the treatment of continuously.Matched group uses other medicine (pain can be pasted, the conventional medication such as prolapse of lumbar intervertebral disc pain relieving plaster, pain-relieving plaster for arthritis).Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: cure: clinical symptoms and sign disappear, as lumbago and skelalgia disappears, straight-leg raising test is greater than 80 °; Effective: clinical symptoms and sign disappear substantially, and pain obviously alleviates, but activity still has light restraint, straight-leg raising test can reach 70 °; Effective: clinical symptoms and sign alleviate or partial disappearance, straight-leg raising test comparatively treats front improvement; Invalid: malaise symptoms and sign are unchanged.
Table 1 liang group patient treatment outcome
As shown in Table 1: experimental group patient, cure 97 examples, effective 49 examples, effective 34 examples, experimental group total effective rate 95.8%; Matched group patient, cures 29 examples, effective 31 examples, and effective 20 examples, matched group total effective rate is 84.2%, and visible experimental group therapeutic effect is better than matched group.
The present invention selects Semen Cuscutae nourishing the liver and kidney, Radix aconiti sinomontani expelling wind and removing dampness, youth-and-old-age clearing away heat-damp and promoting diuresis, Herba Lycopi's blood circulation promoting and blood stasis dispelling, Herba Passiflorae Caeruleae dehumidifying is invigorated blood circulation, Herba Taxilli bone and muscle strengthening, Radix Ampelopsis Cantoniensis dispels the wind removing dampness, Lacca heat-clearing and toxic substances removing, Herba Ephedrae diaphoresis cold expelling, Flos Rosae Chinensis promoting blood flow to regulate menstruation, Semen Juglandis the kidney invigorating intestine moistening, Saussurea cordifolia jiao dispelling cold and analgesia, water Impatientis promoting blood circulation to remove blood stasis, Herba Camptosori Sibirici hemostasis and anti-inflammation, the coupling of various plants material, can play the effect such as promoting blood circulation and stopping pain, expelling wind and removing dampness.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. a blood circulation promoting and blood stasis dispelling unguentum, is characterized in that, is prepared from primarily of following bulk drugs, be mass parts: Semen Cuscutae 10-14, Radix aconiti sinomontani 7-13, youth-and-old-age 9-12, Herba Lycopi 8-13, Herba Passiflorae Caeruleae 6-12, Herba Taxilli 8-14, Radix Ampelopsis Cantoniensis 6-12, Lacca 9-15, Herba Ephedrae 6-13, Flos Rosae Chinensis 12-16, Semen Juglandis 8-15, Saussurea cordifolia 6-14, water Impatientis 9-14, Herba Camptosori Sibirici 7-15.
2. a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 1, is characterized in that, Semen Cuscutae 11-13, Radix aconiti sinomontani 9-11, youth-and-old-age 10-11, Herba Lycopi 9-12, Herba Passiflorae Caeruleae 8-10, Herba Taxilli 10-12, Radix Ampelopsis Cantoniensis 8-10, Lacca 10-14, Herba Ephedrae 8-11, Flos Rosae Chinensis 13-15, Semen Juglandis 10-13, Saussurea cordifolia 8-12, water Impatientis 10-13, Herba Camptosori Sibirici 9-13.
3. a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 1, is characterized in that, Semen Cuscutae 12, Radix aconiti sinomontani 10, youth-and-old-age 10.5, Herba Lycopi 10.5, Herba Passiflorae Caeruleae 9, Herba Taxilli 11, Radix Ampelopsis Cantoniensis 9, Lacca 12, Herba Ephedrae 9.5, Flos Rosae Chinensis 14, Semen Juglandis 11.5, Saussurea cordifolia 10, water Impatientis 11.5, Herba Camptosori Sibirici 11.
4. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) by clean Radix aconiti sinomontani water infiltration, take out, be placed in frying pan, add yellow wine and Mel is mixed thoroughly (mass ratio of yellow wine and Mel is 2:1), the pot that upper cover one bore is less, two pots of seam crossing yellow mud sealing, pressure one weight on lid pot, and paste a paper slip, when moderate heat is heated to paper slip zoom Huang, Guan Huo, takes out;
(2) clean Herba Ephedrae, Radix Ampelopsis Cantoniensis and Saussurea cordifolia yellow wine are boiled to eighty per cant thoroughly, take out, section, is placed in frying pan, and slow fire heats, and frying to dry tack free is degree, takes out, dries;
(3) get clean Flos Rosae Chinensis rice wine slightly to soak, take out, slow fire dries, repetitive operation three times, takes out, dries in the air cool, together pulverized 40-100 mesh sieve (preferably, pulverized 60-80 mesh sieve with step (1) (2) made crude drug; Be more preferably, pulverized 70 mesh sieves);
(4) Semen Cuscutae, youth-and-old-age, Herba Lycopi, Herba Passiflorae Caeruleae, Herba Taxilli, Lacca, Semen Juglandis, water Impatientis and Herba Camptosori Sibirici roguing are cleaned, dry, pulverized 60 mesh sieves, with reflux, extract, 1-2 hour (preferred, reflux, extract, 1.5 hours) at 95% ethanol 80 DEG C, sucking filtration, filtering residue is reflux, extract, again, merge extracted twice liquid, concentrating under reduced pressure becomes clear paste, and filtering residue is for subsequent use;
(5) step (3) made medicated powder and step (4) remaining filtering residue are loaded in penetrating bag, decoct with water, 30-45 minute is boiled in big fire, filters, and collects filtrate, operate twice, merge twice filtrate, heating is condensed into thick paste, mixes with step (4) made clear paste, add the mixing of glyceryl monostearate, stearic acid and white vaseline, obtain blood circulation promoting and blood stasis dispelling unguentum.
5. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 4, is characterized in that, the total amount of step (1) yellow wine and Mel is the 0.8-1.5 of Radix aconiti sinomontani quality doubly (preferred, the total amount of yellow wine and Mel is 1.2 times of Radix aconiti sinomontani quality).
6. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 4, is characterized in that, step (3) is slightly soaked and (preferably, slightly soaked 18-25 minute in 15-28 minute; Be more preferably, slightly soak 21 minutes).
7. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 4, is characterized in that, the 5-7 that the amount of step (4) 95% ethanol is institute's lixiviate crude drug quality is (preferred, 6 times that the amount of 95% ethanol is institute's lixiviate crude drug quality) doubly.
8. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 4, is characterized in that, step (5) amount of water is the 6-7 of total raw material medicine quality doubly (preferred, amount of water is 6.5 times of total raw material medicine quality).
9. the preparation method of a kind of blood circulation promoting and blood stasis dispelling unguentum as claimed in claim 4, is characterized in that, step (5) big fire is boiled 35-40 minute (preferred, big fire boils 37.5 minutes).
10. the application of a kind of blood circulation promoting and blood stasis dispelling unguentum as described in as arbitrary in claim 1-3 when preparing the medicine for the treatment of prolapse of lumbar intervertebral disc.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105560477A (en) * | 2016-01-26 | 2016-05-11 | 王健军 | Meridian and collateral dredging hot compress salt and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391067A (en) * | 2008-10-30 | 2009-03-25 | 邱志坚 | Preparation method of Chinese herbal medicine for treating lumbar vertebra disc protrusion |
| CN104667023A (en) * | 2015-03-24 | 2015-06-03 | 陈志建 | Ointment capable of promoting blood circulation and removing blood stasis and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391067A (en) * | 2008-10-30 | 2009-03-25 | 邱志坚 | Preparation method of Chinese herbal medicine for treating lumbar vertebra disc protrusion |
| CN104667023A (en) * | 2015-03-24 | 2015-06-03 | 陈志建 | Ointment capable of promoting blood circulation and removing blood stasis and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560477A (en) * | 2016-01-26 | 2016-05-11 | 王健军 | Meridian and collateral dredging hot compress salt and preparation method thereof |
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Address after: 550000 Guizhou Province, Guiyang city Nanming District Sha Chong Road No. 87 Garden District 2 building 1-502 Applicant after: Fan Qiaolan Address before: 250014 Shandong Province, Lixia District, Ji'nan Road, No. 26 liberation Applicant before: Fan Qiaolan |
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