CN1041878A - 恢复、刺激和促进毛发生长的制品及其制法 - Google Patents

恢复、刺激和促进毛发生长的制品及其制法 Download PDF

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CN1041878A
CN1041878A CN88107294A CN88107294A CN1041878A CN 1041878 A CN1041878 A CN 1041878A CN 88107294 A CN88107294 A CN 88107294A CN 88107294 A CN88107294 A CN 88107294A CN 1041878 A CN1041878 A CN 1041878A
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acid
described goods
semen trigonellae
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尤塔·迈
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Priority to HU884753A priority Critical patent/HUT51128A/hu
Priority claimed from HU884753A external-priority patent/HUT51128A/hu
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Priority to CN88107294A priority patent/CN1041878A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Networks Using Active Elements (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydroponics (AREA)
  • Cultivation Of Plants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
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Abstract

恢复、刺激和促进生物毛发生长的制品，其含有胡芦巴碱或胡芦巴酸，尤以由胡芦巴亚科植物，特别是由苦豆(Trigonella phoenum graecum)中得到的提取液为佳。

Description

本发明涉及恢复、刺激和促进生物毛发生长的制品及其制法。
过去已经研制、试验和销售大量生发剂，但是在这众多的产品中，没有一个产品能够达到理想的效果，甚至还有严重的副作用。
头发变稀或减少通常是由于头皮的强烈收缩，从而中断或阻止了流向毛囊的血液循环。供给毛囊的营养物质和氧气的减少对毛发生长具有重要作用的角蛋白的产生造成严重影响。
本发明的任务是研制一种含有天然物质的制品，它能刺激头皮内的血液循环。
解决这一任务的途径是使该制品含有胡芦巴碱或胡芦巴酸。
这类物质具有扩张血管的作用，因而使毛囊营养物质的供应得到改善，毛囊组织获得再生，同时产生多毛现象，即头发长得又长又密，色素加深。
胡芦巴碱可通过人工合成得到。但是尤以胡芦巴亚科植物，特别是苦豆（Trigonella    phoenum    graecum）的提取液为佳。将苦豆种子先浸胀，然后用水提取，能更有效地获得这种提取液。获得这种提取液的另一个方法是对种子进行冷榨，取用其液汁和/或浆末。
得到的胡芦巴碱最好含有咖啡碱（caffearine）、N-甲基烟酰-3-羧基甜菜酸（N-methylnicotinyl-3-carboxyl    betaine    acid）和N-甲基吡啶-3-羧基甜菜酸（N-methylpyridine-3-carboxyl    betaine    acid）。还可含有甾族糖苷和/或具有大量赖氨酸和色氨酸的蛋白质以及类似半乳糖的胶浆。
如果将维生素B6加入胡芦巴碱提取液，则可提高该制品的疗效，因为维生素B6是头发的主要营养物质，因此对头发生长具有保健作用。
将乙醇和防腐剂加入提取液中，则可得到高增效作用。
胡芦巴碱也可与苦豆水提取液混合，这不仅能提高疗效，而且还可扩大作用范围。
一种可能的使用方式是将溶液置于滴瓶内，但是这种制品也可装在胶囊中。这两种情况均为口服用药。然而其他可以想像得到的使用方法也包括在本发明的范围内。特别值得一提的是采用饮料形式，尤其是喷雾状物的速溶饮料。
使用本制品时，可配制成：5ml制品中含有273mg苦豆提取液，5mg维生素B6，11.4V/V乙醇和0.1m/V    nipastate。每晨早餐前取20滴溶于250毫升冷水中。用后3至5周即可看到该制品对头皮作用的最初积极征兆。
采用胶囊形式时，一所不用醇和nipastate，而采用核黄素、烟酰胺、泛酸钙和叶酸等维生素代之。这些物质的用量最好分别为：核黄素1.5mg，烟酰胺10mg，b（+）泛酸钙8mg和叶酸0.4mg。

Claims (16)

1、恢复、刺激和促进生物毛发生长的制品，其特征在于该制品含有胡芦巴碱或胡芦巴酸。
2、根据权利要求1的制品，其特征在于该制品包括胡芦巴亚科植物的提取液。
3、根据权利要求2的制品，其特征在于该制品包括苦豆（Trigonella  phoenum  graecum）的提取液。
4、根据权利要求2或3的制品，其特征在于该制品包括胡芦巴亚科植物种子的提取液。
5、根据权利要求1至4中至少一项所述的制品，其特征在于胡芦巴含有咖啡碱（Caffearine）、N-甲基烟酰-3-羧基甜菜酸（N-methylnicotinyl-3-carboxyl  betaine  acid）和N-甲基吡啶-3-羧基甜菜酸（N-methylpyr-idine-3-carboxyl  betaine  acid）。
6、根据权利要求1至5中至少一项所述的制品，其特征在于该制品含有甾族糖苷。
7、根据权利要求1至6中至少一项所述的制品，其特征在于该制品中含有带大量赖氨酸和色氨酸的蛋白质。
8、根据权利要求1至7中至少一项所述的制品，其特征在于含有类半乳糖的胶浆。
9、根据权利要求1至8中至少一项所述的制品，其特征在于含有维生素B6。
10、根据权利要求1至9中至少一项所述的制品，其特征在于含有乙醇。
11、根据权利要求1至10中至少一项所述的制品，其特征在于含有防腐剂nipastate。
12、根据权利要求1至9中至少一项所述的制品，其特征在于采用其他形式，尤其是胶囊形式时，还含有核黄素和/或烟酰胺和/或泛酸钙和/或叶酸。
13、生产按权利要求1至12中至少一项所述制品的方法，其特征在于该制品包在可分解的胶囊中被摄取。
14、生产按权利要求1至12中至少一项所述制品的方法，其特征在于采用干燥状态或液体状态的该制品时，可制成饮料形式或速溶细颗粒形式。
15、生产按权利要求1至12中至少一项所述制品的方法，其特征在于将胡芦巴碱或胡芦巴酸或含有胡芦巴碱或胡芦巴酸的制品装在滴瓶内。
16、根据权利要求1至15的方法，其特征在于对苦豆（Trigonella  phoenum  graecum）种子进行冷榨，取用其液汁和/或浆末。
CN88107294A 1986-02-06 1988-10-18 恢复、刺激和促进毛发生长的制品及其制法 Pending CN1041878A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU884753A HUT51128A (en) 1986-02-06 1988-09-14 Process for producing composition for reanimating, improving and strangthening growth of hair
CN88107294A CN1041878A (zh) 1987-05-07 1988-10-18 恢复、刺激和促进毛发生长的制品及其制法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP87106650A EP0289639B2 (de) 1987-05-07 1987-05-07 Verwendung von Trigonellin zum Wiederbeleben und zum Anregen und Verstärken des Haarwuchses
HU884753A HUT51128A (en) 1986-02-06 1988-09-14 Process for producing composition for reanimating, improving and strangthening growth of hair
CN88107294A CN1041878A (zh) 1987-05-07 1988-10-18 恢复、刺激和促进毛发生长的制品及其制法

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CN1041878A true CN1041878A (zh) 1990-05-09

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ID=26108007

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CN88107294A Pending CN1041878A (zh) 1986-02-06 1988-10-18 恢复、刺激和促进毛发生长的制品及其制法

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EP (1) EP0289639B2 (zh)
JP (1) JPS63297316A (zh)
CN (1) CN1041878A (zh)
AT (1) ATE66138T1 (zh)
AU (1) AU613622B2 (zh)
DD (1) DD273379A5 (zh)
DE (1) DE3603601C3 (zh)
DK (1) DK251088A (zh)
ES (1) ES2023848T5 (zh)
FI (1) FI881723A (zh)
GR (1) GR3002846T3 (zh)
IL (1) IL85981A (zh)
NO (1) NO881607L (zh)
NZ (1) NZ226001A (zh)
PT (1) PT87437B (zh)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113993546A (zh) * 2019-07-05 2022-01-28 雀巢产品有限公司 使用葫芦巴碱和维生素预防或治疗骨骼肌病症或障碍的组合物和方法
CN114080222A (zh) * 2019-07-05 2022-02-22 雀巢产品有限公司 使用葫芦巴碱产生用于治疗或预防生理障碍或状况的胞内烟酰胺腺嘌呤二核苷酸(nad+)的组合物和方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2009204A1 (en) * 1989-02-06 1990-08-06 Andries J. C. Strydom Medicament
US5133958A (en) * 1989-04-20 1992-07-28 Erwin Stuckler Agent for nail, skin and hair care
AU5425590A (en) * 1989-04-20 1990-11-16 Erwin Stuckler Preparation for care of nails, skin and hair
CA2075502A1 (en) * 1990-02-13 1991-08-14 Syunpei Mitsuyama Use of alkanamidocarboxybetaines
FR2733421B1 (fr) * 1995-04-28 1997-06-06 Oreal Utilisation de derives de l'hormone stimulatrice des melanocytes de type alpha pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
JP3660485B2 (ja) * 1997-10-17 2005-06-15 花王株式会社 白髪防止剤
PL190755B1 (pl) * 1999-01-07 2006-01-31 Pharmena Sp Z Oo Preparat do leczenia i profilaktyki chorób skóry
GB2359021B (en) * 2000-02-09 2002-04-24 Andromeda Trading Ltd Method and composition for promoting hair growth
DE102004013798A1 (de) * 2004-03-20 2005-10-06 Wella Aktiengesellschaft Verwendung von Mitteln zur kosmetischen Behandlung von Keratin enthaltenden Material
DE102004039983A1 (de) * 2004-08-12 2006-03-02 Keller, Ben Pharmazeutische oder kosmetische Zusammensetzung
CN110484465B (zh) * 2019-08-01 2021-06-04 金华康扬环境科技有限公司 一种vbnc细菌的复苏培养基及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118882C2 (de) * 1981-05-13 1985-11-14 Rudolf V. Dr.rer.nat Dipl.-Chem. 5024 Pulheim Noronha Mittel gegen Haarausfall und zur Förderung des Haarwuchs
DE3225056C2 (de) * 1982-07-05 1985-08-01 Friedrich-Karl Dr. Med. 2120 Lueneburg Koenig Verwendung des zerkleinerten Samens des Bockshornklees (Trigonella foenum-graecum) als Wirkstoff zur Bekämpfung toxischer Leberschädigung und/oder zur Verbesserung der Leberfunktion
FR2551972B1 (fr) * 1983-09-21 1986-05-16 Bouzid Moussaad Lotion antipelliculaire et anti-chute

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113993546A (zh) * 2019-07-05 2022-01-28 雀巢产品有限公司 使用葫芦巴碱和维生素预防或治疗骨骼肌病症或障碍的组合物和方法
CN114080222A (zh) * 2019-07-05 2022-02-22 雀巢产品有限公司 使用葫芦巴碱产生用于治疗或预防生理障碍或状况的胞内烟酰胺腺嘌呤二核苷酸(nad+)的组合物和方法

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DE3603601C3 (de) 1999-12-23
IL85981A (en) 1992-02-16
AU613622B2 (en) 1991-08-08
PT87437A (pt) 1989-05-31
DK251088D0 (da) 1988-05-06
GR3002846T3 (en) 1993-01-25
DD273379A5 (de) 1989-11-15
EP0289639A1 (de) 1988-11-09
FI881723A (fi) 1988-11-08
NO881607L (no) 1988-11-08
DK251088A (da) 1988-11-08
PT87437B (pt) 1993-01-29
DE3603601C2 (de) 1994-03-17
ATE66138T1 (de) 1991-08-15
ES2023848T5 (es) 1997-02-16
AU1580588A (en) 1988-11-10
NZ226001A (en) 1991-03-26
FI881723A0 (fi) 1988-04-13
DE3603601A1 (de) 1987-08-13
EP0289639B2 (de) 1996-12-11
ES2023848B3 (es) 1992-02-16
JPS63297316A (ja) 1988-12-05
EP0289639B1 (de) 1991-08-14

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