CN104186970A - Fish feed for preventing and treating hemorrhagic diseases of grass carps - Google Patents
Fish feed for preventing and treating hemorrhagic diseases of grass carps Download PDFInfo
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Abstract
The invention provides a fish feed for preventing and treating hemorrhagic diseases of grass carps. The fish feed is prepared from the following components by weight: 100-150g of Chinese pulsatilla root, 100-150g of common scouring rush herb, 100-150g of manyprickle acathopanax root, 60-80g of weeping forsythia capsule, 60-80g of great burdock achene, 60-80g of white paeony root, 60-80g of oyster shell, 60-80g of folium phyllostachys, 60-80g of akebia stem, 60-80g of dwarf lilyturf tuber, 60-80g of radix rehmanniae, 60-80g of largetrifoliolious bugbane rhizome, 60-80g of figwort root, 40-60g of garden burnet root, 40-60g of red peony root, 40-60g of szechwan chinaberry fruit, 40-60g of immature tangerine peel, 20-30g of liquorice, 20-30g of seed of Job's tears, 5-20g of florfenicol sodium succinate and 5-20mg of phytohemagglutinin. The fish feed is simple in proportioning, is convenient to use, is specially used for hemorrhagic diseases of grass carps, and has good treatment effects.
Description
technical field:
The present invention relates to technical field of pharmaceuticals, relate in particular to a kind of fish meal of preventing and treating hemorrhagic disease of grass carp.
background technology:
Hemorrhagic disease of grass carp is the fish disease caused by virus that a kind of Prevalent district of nurture of fish fingerlings stage is extensive, epidemic season is long, the incidence of disease is high, the death rate is high, harmfulness is large.The Grass Carp Juveniles of the long 2.5-15cm of main harm body and the black carp of 1 full age, large grass carps more than 2 full ages is also ill sometimes.Popular water temperature is at 20-33 ℃, the suitableeest popular water temperature 27-30 ℃; But work as water quality deterioration, dissolved oxygen in water is low, and transparency is low, in water, total nitrogen, organic nitrogen, nitrite nitrogen and organic matter oxygen demand are high, and water temperature changes greatly, and fish body is lower for the resistance, when the many and virulence of the quantity of virus is strong, also have morbidity when 12 ℃ of water temperatures and 34.5 ℃.This disease in Hubei, the main Fish-water Fish Farming provinces，municipalities and autonomous regions such as Hunan, Guangdong, Guangxi, Jiangxi, Fujian, Jiangsu, Zhejiang, Anhui, Shanghai, Sichuan, Chongqing are all popular.This disease can be carried out horizontal transmission by contaminated water, food etc., also can carry out vertical transmission by ovum.At present in GB fish medicine for preventing the medicine of the viral diseases such as fish hemorrhage to have heat-clearing loose etc.This disease pathogen is grass carp intestines arc virus GCRV, or GCHV GCHV, and virus is individual minimum, is graininess, must under electron microscope, just can see clearly.Symptom-red muscularity, tears the skin of disease fish or aims at sunlight or light perspective fish body, flush under visible skin; Enteritis type, sick fish enteron aisle is congested, often follows loose squama, flush.
In prior art, Chinese patent application 201210471907.7 discloses a kind of for preventing and treating the medicine of hemorrhagic disease of grass carp, comprises epi-nutgall acid Epigallo-catechin gallate (EGCG).Epi-nutgall acid Epigallo-catechin gallate (EGCG) is Powdered.During use, the concentration range of epi-nutgall acid Epigallo-catechin gallate (EGCG) is 5 to 50 μ g/mL.For another example Chinese patent application 2013106306891, for preventing and treating the feed of hemorrhagic disease of grass carp, comprise the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, kuh-seng, Herba Andrographitis, cacumen biotae, the coptis, wilsonii, Chinese gall, Asiatic plantain, Lygodium japonicum, Ligusticum wallichii, hawthorn, peppermint, oriental wormwood, the Chinese bulbul, purslane, the stem of noble dendrobium, asafoetide, the bighead atractylodes rhizome, white wine grass, sessile alternanthera herb and Radix Glycyrrhizae.Chinese medicine or its extract, for antiviral, have certain superiority, as low in drug residue, so it is necessary that Study of Traditional Chinese Medicine antiviral drugs is used for the treatment of hemorrhagic disease of grass carp.
summary of the invention:
The object of the invention is to overcome the shortcoming existing in prior art, provide a kind of proportioning simple, easy to use, specially for hemorrhagic disease of grass carp, a kind of fish meal of preventing and treating hemorrhagic disease of grass carp that result for the treatment of is good.
To achieve these goals, the invention provides a kind of fish meal of preventing and treating hemorrhagic disease of grass carp, wherein, according to unit of weight, configure following each component:
The Chinese bulbul, scouring rush, each 100-150g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 60-80g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 40-60g of rascal, Radix Glycyrrhizae, each 20-30g of the seed of Job's tears, Florfenicol sodium succinate 5-20g, plant blood cell lectin 5-20mg.Dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
Or, according to unit of weight, configure following each component:
The Chinese bulbul, scouring rush, each 100-120g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 60-70g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 40-50g of rascal, Radix Glycyrrhizae, each 20-25g of the seed of Job's tears, Florfenicol sodium succinate 5-10g, plant blood cell lectin 5-10mg.Dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
Or, according to unit of weight, configure following each component:
The Chinese bulbul, scouring rush, each 120-150g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 70-80g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 50-60g of rascal, Radix Glycyrrhizae, each 25-30g of the seed of Job's tears, Florfenicol sodium succinate 10-20g, plant blood cell lectin 10-20mg.Dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
The preparation method of the fish meal of control hemorrhagic disease of grass carp is as follows:
By each bulk drug component (Chinese bulbul in above-mentioned Chinese medicine composition, scouring rush, wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, rascal, Radix Glycyrrhizae, the seed of Job's tears) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out reduced pressure concentration and obtain medicinal extract, medicinal extract is joined in the ethanolic solution that the determining alcohol with respect to 2 ~ 3 times of amounts of mixture quality is 90% ~ 95%, stir completely and dissolve, subsequently 4 ℃ of following standing over night of temperature, subsequent filtration, filtrate is carried out to reduced pressure concentration and remove ethanol, the lotion of acquisition is pulverized, and adds Florfenicol sodium succinate, after plant blood cell lectin, mix gains and starch, CMC mixes according to mass ratio 1:2:1, with 14 mesh sieves, granulates, and toasts 30 minutes, obtains granular medicine, big or small 0.5-1mm.
Use: this medicine can mix feeding in graininess fish material, according to the quality of 0.5:1, compares proportioning.
Further, also can be on this granule medicament basis of (being called drug core), i.e. the feed of the parcel in appearance dressing of this medicine, is prepared into and take the fish material that this medicine is core, is specially:
By basal feed: (by dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g) add water and stir as water content 65%, add Sodium Hydroxymethyl Stalcs to be thickened to thick, drug core is repeatedly rolled across on viscous fluid, after dry, roll again for a moment, basal feed is wrapped on the outer wall of drug core, thickness is 0.3-0.5mm.After dry, be able to fish material.
Advantage of the present invention is, proportioning is simple, easy to use, and specially for hemorrhagic disease of grass carp, result for the treatment of is good, and to grass carp arc reovirus virus GCRV, or GCHV GCHV has deactivation, and result for the treatment of is good.
the specific embodiment:
Principle:
The present invention with direct deactivation, suppress the viral Chinese bulbul, scouring rush; The wilsonii that reaches antivirus action with Promote immunity is monarch drug in a prescription, uses in a large number medicine as ministerial drug, adjutant simultaneously and makes medicine.As, clearing away heart-fire detoxification is to the medicine capsule of weeping forsythia, great burdock achene; Clearing liver hemostasis to the medicine root of herbaceous peony, oyster; Reducing fever and causing diuresis to the medicine leaf of bamboo, akebi; Joint venture enrich blood to medicine tuber of dwarf lilyturf, the dried rhizome of rehmannia; Clearing heat and detoxicating to medicine rattletop, radix scrophulariae; These are ministerial drug to medicine.Soothing the liver promoting the circulation of qi is to medicine Fructus meliae toosendan, rascal; What gut purge was invigorated blood circulation is adjutant to medicine garden burnet, the radix paeoniae rubrathe; Radix Glycyrrhizae, the seed of Job's tears are for making medicine.On this basis, add antibacterial Florfenicol sodium succinate, and the plant blood cell lectin of hemostasis further strengthens effect simultaneously.In the present invention, in active ingredient, Anthraquinones has direct killing action to virus.Flavonoids, polysaccharide and derivative thereof, triterpene compound and derivative thereof, alkaloid and glycoside etc., be all by stoping the adsorption process of virion to host cell, and performance suppresses virus.Meanwhile, have antiviral proliferation function in born of the same parents, anti-expression (overflowing) is infection effect again.
Sick fish type and pathological data
Treatment contrast, select at random the grass carp of hemorrhagic disease, be divided into 5 groups, every group 24 (three kinds of incidence types, 8 every group), the traditional Chinese medicine powder that the traditional rheum officinale of feeding, Radix Isatidis, the root of large-flowered skullcap, golden cypress mix for group one, throw in quick lime, bleaching powder and chlorine-containing disinfectant for group two, what use plant blood cell anticoagulin is group three, use broad spectrum antibiotic Florfenicol sodium succinate for organizing four, use the present invention for organizing five, under equal conditions, within three days, observe afterwards.
Antiviral experimental data:
Interior resisting virus experiment to grass carp
Get fish, by body weight, divide 2 groups at random: virus infections control group and intact animal control group, except Normal group, grass carp is slightly anaesthetized, with the grass carp intestines arc virus infection of 15 LDSD, every 0.1ml, from infecting, start administration the previous day, virus infections control group feeding every day of the present invention 2 times, continuous 5 days, the 6th day, after taking body weight, fix, dissect, get liver and calculate liver exponential quantity, calculate liver index inhibiting rate
Heavy (the g)/body weight (g) * 100 of liver index=liver
Liver index inhibiting rate=(virus control group liver Mean value of index-experimental group liver Mean value of index)/virus control group liver Mean value of index * 100%
Liver index is larger, represents that liver pathological changes degree is serious, (because hemorrhage causes each internal organs hemorrhage, select internal organs as index, also can select lung to carry out lung assessment of indices)
Hepatic tissue is fixed with 10% formaldehyde, ethanol series dehydration, dimethylbenzene is transparent, FFPE, slice thickness 4-5 micron, HE dyeing, observes blood lipid with ordinary optical microscope and changes, select antiviral group of broad spectrum antibiotic (Florfenicol sodium succinate) as a comparison, can find out that successful of the present invention is better than broad spectrum antibiotic.
The impact (n=10) of liver's checking (virus is observed)
Can find, of the present invention to viral inhibiting rate apparently higher than direct use broad spectrum antibiotic.
The experiment of toxicity to rat:
Acute oral (LD50) > 500mg/kg,
It is acute through skin (LD 50) > 2000mg/kg,
Belong to low toxicity.
Object lesson 1
Zhao family's one cultivating pool, area 2000 square meters, approximately 5 meters of the depth of waters, put grass carp 1.5 ten thousand tails in a suitable place to breed, start morbidity dead fish successively in 8 months, and every day, the quantity of dead fish was multiplied, and a day dead grass carp reaches tail more than 500 at most.Detect disease fish, find that there is the red cheek lid of the red fin of part, the meaning is suffered from hemorrhagic disease of grass carp, after cutting open, the little vascular injury of each internal organs, disseminated intravascular coagulation, intestines wall: mucous layer epithelial cell swelling, tunica propria is hemorrhage, enteric epithelium breaks, be diagnosed as hemorrhagic disease of grass carp, use the Chinese bulbul of the present invention, scouring rush, each 150g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 80g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 60g of rascal, Radix Glycyrrhizae, each 30g of the seed of Job's tears, Florfenicol sodium succinate 20g, plant blood cell lectin 20mg.By each bulk drug component (Chinese bulbul in above-mentioned Chinese medicine composition, scouring rush, wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, rascal, Radix Glycyrrhizae, the seed of Job's tears) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out reduced pressure concentration and obtain medicinal extract, medicinal extract is joined in the ethanolic solution that the determining alcohol with respect to 2 ~ 3 times of amounts of mixture quality is 90% ~ 95%, stir completely and dissolve, subsequently 4 ℃ of following standing over night of temperature, subsequent filtration, filtrate is carried out to reduced pressure concentration and remove ethanol, the lotion of acquisition is pulverized, and adds Florfenicol sodium succinate, after plant blood cell lectin, mix gains and starch, CMC mixes according to mass ratio 1:2:1, with 14 mesh sieves, granulates, and toasts 30 minutes, obtains granular medicine, big or small 0.5-1mm.
On the basis of this granule medicament (being called drug core), i.e. the feed of the parcel in appearance dressing of this medicine, is prepared into and take the fish material that this medicine is core, is specially:
By basal feed: (by dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g) add water and stir as water content 65%, add Sodium Hydroxymethyl Stalcs to be thickened to thick, drug core is repeatedly rolled across on viscous fluid, after dry, roll again for a moment, basal feed is wrapped on the outer wall of drug core, thickness is 0.3-0.5mm.After dry, be able to fish material.
Above-mentioned consumption is the consumption of 100 fishes, is multiplied by multiple goes preparation according to the quantity of fish.
1 meal/day, continuous 6 days, the dead quantity of the 1st day grass carp after medication was 509 tails, the 2nd day dead quantity 425 tails of grass carp, the 3rd day dead 320 tails, the 4th day dead 192, the 5th day dead 64, and hemorrhagic disease of grass carp does not occur afterwards again, and general mortality rate is 0.80%.
Example 2
Lin Jia fish pond 1300 square meters, put 8000 tails in a suitable place to breed, summer and autumn find that fish are dead successively, dead 468 of the highest day, dissect and find, the serious anaemia of part grass carp, leukocyte count is 40% of healthy grass carp, in liver cell endochylema, there is eosinophilic inclusion, the little vascular injury of each internal organs, disseminated intravascular coagulation.In addition, find that part grass carp grass carp intestinal is seriously congested, gently scrape enteron aisle inwall without obscission, the light or irregular colour of liver color, gall-bladder enlargement, slight gill rot.Be diagnosed as hemorrhagic disease of grass carp, use the present invention.
The Chinese bulbul, scouring rush, each 100g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 60g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 40g of rascal, Radix Glycyrrhizae, each 20g of the seed of Job's tears, Florfenicol sodium succinate 5g, plant blood cell lectin 5mg.
By each bulk drug component (Chinese bulbul in above-mentioned Chinese medicine composition, scouring rush, wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, rascal, Radix Glycyrrhizae, the seed of Job's tears) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out reduced pressure concentration and obtain medicinal extract, medicinal extract is joined in the ethanolic solution that the determining alcohol with respect to 2 ~ 3 times of amounts of mixture quality is 90% ~ 95%, stir completely and dissolve, subsequently 4 ℃ of following standing over night of temperature, subsequent filtration, filtrate is carried out to reduced pressure concentration and remove ethanol, the lotion of acquisition is pulverized, and adds Florfenicol sodium succinate, after plant blood cell lectin, mix gains and starch, CMC mixes according to mass ratio 1:2:1, with 14 mesh sieves, granulates, and toasts 30 minutes, obtains granular medicine, big or small 0.5-1mm.
On the basis of this granule medicament (being called drug core), i.e. the feed of the parcel in appearance dressing of this medicine, is prepared into and take the fish material that this medicine is core, is specially:
By basal feed: (by dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g) add water and stir as water content 65%, add Sodium Hydroxymethyl Stalcs to be thickened to thick, drug core is repeatedly rolled across on viscous fluid, after dry, roll again for a moment, basal feed is wrapped on the outer wall of drug core, thickness is 0.3-0.5mm.After dry, be able to fish material.
This example is 100 grass carp use, is multiplied by multiple goes preparation according to fish tail number.
1 meal/day, continuous 8 days, the dead quantity of the 1st day grass carp after medication was 357 tails, the 2nd day dead quantity 197 tails of grass carp, and the 3rd day dead 115 tails, the 4th day dead 54 tails, after this do not have fish Mortality, and general mortality rate is 0.90%.
Example 3,
Huang Jia fish pond 1000 square meters, put 7000 tails in a suitable place to breed, summer and autumn find that fish are dead successively, dead 392 of the highest day, dissect and find, the serious anaemia of part grass carp, leukocyte count is 40% of healthy grass carp, in liver cell endochylema, there is eosinophilic inclusion, the little vascular injury of each internal organs, disseminated intravascular coagulation.In addition, find that part grass carp grass carp intestinal is seriously congested, gently scrape enteron aisle inwall without obscission, the light or irregular colour of liver color, gall-bladder enlargement, slight gill rot.Be diagnosed as hemorrhagic disease of grass carp, use the present invention.
The Chinese bulbul, scouring rush, each 120g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 70g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 30g of rascal, Radix Glycyrrhizae, each 25g of the seed of Job's tears, Florfenicol sodium succinate 8g, plant blood cell lectin 8mg.
By each bulk drug component (Chinese bulbul in above-mentioned Chinese medicine composition, scouring rush, wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, rascal, Radix Glycyrrhizae, the seed of Job's tears) grind to form respectively fine powder, mix, obtain mixture, mixture is joined in the water of 6 ~ 8 times of amounts and decoct, each decoction 2 ~ 4 hours, decoct 3 times, decocted rear filtration at every turn, filtrate is mixed, carry out reduced pressure concentration and obtain medicinal extract, medicinal extract is joined in the ethanolic solution that the determining alcohol with respect to 2 ~ 3 times of amounts of mixture quality is 90% ~ 95%, stir completely and dissolve, subsequently 4 ℃ of following standing over night of temperature, subsequent filtration, filtrate is carried out to reduced pressure concentration and remove ethanol, the lotion of acquisition is pulverized, and adds Florfenicol sodium succinate, after plant blood cell lectin, mix gains and starch, CMC mixes according to mass ratio 1:2:1, with 14 mesh sieves, granulates, and toasts 30 minutes, obtains granular medicine, big or small 0.5-1mm.
On the basis of this granule medicament (being called drug core), i.e. the feed of the parcel in appearance dressing of this medicine, is prepared into and take the fish material that this medicine is core, is specially:
By basal feed: (by dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g) add water and stir as water content 65%, add Sodium Hydroxymethyl Stalcs to be thickened to thick, drug core is repeatedly rolled across on viscous fluid, after dry, roll again for a moment, basal feed is wrapped on the outer wall of drug core, thickness is 0.3-0.5mm.After dry, be able to fish material.
This example is 100 grass carp use, is multiplied by multiple goes preparation according to fish tail number.
1 meal/day, continuous 8 days, the dead quantity of the 1st day grass carp after medication was 322 tails, the 2nd day dead quantity 186 tails of grass carp, and the 3rd day dead 59 tails, the 4th day dead 27 tails, after this do not have fish Mortality, and general mortality rate is 0.84%
To sum up, proportioning of the present invention is simple, easy to use, and specially for hemorrhagic disease of grass carp, result for the treatment of is good, and to grass carp arc reovirus virus GCRV, or GCHV GCHV has deactivation, and result for the treatment of is good.
Claims (3)
1. a fish meal of preventing and treating hemorrhagic disease of grass carp, is characterized in that, according to unit of weight, configures following each component:
The Chinese bulbul, scouring rush, each 100-150g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 60-80g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 40-60g of rascal, Radix Glycyrrhizae, each 20-30g of the seed of Job's tears, Florfenicol sodium succinate 5-20g, plant blood cell lectin 5-20mg; Dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
2. prevent and treat according to claim 1 the fish meal of hemorrhagic disease of grass carp, it is characterized in that, according to unit of weight, configure following each component:
The Chinese bulbul, scouring rush, each 100-120g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 60-70g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 40-50g of rascal, Radix Glycyrrhizae, each 20-25g of the seed of Job's tears, Florfenicol sodium succinate 5-10g, plant blood cell lectin 5-10mg, dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
3. prevent and treat according to claim 1 the fish meal of hemorrhagic disease of grass carp, it is characterized in that, according to unit of weight, configure following each component:
The Chinese bulbul, scouring rush, each 120-150g of wilsonii, the capsule of weeping forsythia, great burdock achene, the root of herbaceous peony, oyster, the leaf of bamboo, akebi, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, rattletop, each 70-80g of radix scrophulariae, garden burnet, the radix paeoniae rubrathe, Fructus meliae toosendan, each 50-60g of rascal, Radix Glycyrrhizae, each 25-30g of the seed of Job's tears, Florfenicol sodium succinate 10-20g, plant blood cell lectin 10-20mg, dregs of beans 100g, fish meal 50g, wheat flour 300g, corn flour 500g, salt 5g, vitamin 2g.
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| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
| CN106689818A (en) * | 2016-12-28 | 2017-05-24 | 青岛嘉瑞生物技术有限公司 | Aquatic product immunopotentiator based on salicornia bigelovii torr resource utilization |
| CN106974986A (en) * | 2017-05-31 | 2017-07-25 | 铜仁市万山区生态渔业养殖有限公司 | A kind of additive for preventing and treating yellow croaker hemorrhage |
| CN107410693A (en) * | 2017-06-27 | 2017-12-01 | 铜仁市万山区生态渔业养殖有限公司 | A kind of feed addictive for preventing and treating hemorrhagic disease of grass carp and preparation method thereof |
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| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
| CN106689818A (en) * | 2016-12-28 | 2017-05-24 | 青岛嘉瑞生物技术有限公司 | Aquatic product immunopotentiator based on salicornia bigelovii torr resource utilization |
| CN106974986A (en) * | 2017-05-31 | 2017-07-25 | 铜仁市万山区生态渔业养殖有限公司 | A kind of additive for preventing and treating yellow croaker hemorrhage |
| CN107410693A (en) * | 2017-06-27 | 2017-12-01 | 铜仁市万山区生态渔业养殖有限公司 | A kind of feed addictive for preventing and treating hemorrhagic disease of grass carp and preparation method thereof |
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