CN104180619A

CN104180619A - Scutellaria baicalensis drying method

Info

Publication number: CN104180619A
Application number: CN201410418447.0A
Authority: CN
Inventors: 杨逸霏; 孙志芳; 石红艳; 刘金磊
Original assignee: Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
Current assignee: Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
Priority date: 2014-08-25
Filing date: 2014-08-25
Publication date: 2014-12-03

Abstract

The invention relates to a Scutellaria baicalensis drying method. The method is characterized by including the steps of taking fresh Scutellaria baicalensis, freezing and steaming before drying. Prepared Scutellaria baicalensis medicinal materials are high in extract content, high in content of baicalin which is a main active ingredient, and stable in quality.

Description

A kind of drying means of the root of large-flowered skullcap

Invention field

The present invention relates to medicine method for making, particularly a kind of drying means of the root of large-flowered skullcap, belongs to medical technical field.

Background technology

The root of large-flowered skullcap is the dry root of Labiatae herbaceos perennial root of large-flowered skullcap Scutellaria baicalensis Georgi, and bitter is cold in nature, heat-clearing and damp-drying drug, purging intense heat and detonicating, cool blood, hemostasis, heat extraction are antiabortive, cure mainly damp-warm syndrome, the heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, rushes down dysentery, jaundice, cough with lung heat, high hot polydipsia, blood-head is told nosebleed, carbuncle sore tumefacting virus, the diseases such as fetal irritability.

" Chinese pharmacopoeia " regulation: root of large-flowered skullcap spring, Qiu Erji excavate, and remove fibrous root and silt, hit tertia after solarization, dry.Extract in the traditional drying method root of large-flowered skullcap, content of baicalin are low, quality of medicinal material poor stability.

Summary of the invention

Object of the present invention provides a kind of new root of large-flowered skullcap drying means, and the root of large-flowered skullcap extract of preparation, content of baicalin are high, quality of medicinal material good stability.

The object of the present invention is achieved like this:

A drying means for the root of large-flowered skullcap, is characterized in that: get cadmium yellow a kind of reed mentioned in ancient books, freezing, steaming is rear dry.

The drying means of a kind of root of large-flowered skullcap of the present invention, is characterized in that: freezing is to be refrigerated to-5 DEG C with down to freezing, dry.

The drying means of a kind of root of large-flowered skullcap of the present invention, is characterized in that: dry is dry or dry or dry after freezing;

So far completed the present invention, radix scutellariae medicinal materials extract content prepared by the present invention is high, and main active content of baicalin is high, and quality of medicinal material is stable.

Further illustrate usefulness of the present invention below by test example, test example is intended to further illustrate usefulness of the present invention, but not restriction of the present invention.

To, with a collection of cadmium yellow a kind of reed mentioned in ancient books, be dried by the following method.

1, dry: remove impurity, dry.

2, after steaming, dry: remove impurity, steam 10 minutes, take out, vexed, dry.

3, frozen steamed dries: remove impurity, be refrigerated to-5 DEG C with down to freezing, steam 10 minutes, and vexed, dry.

One, the dry radix scutellariae medicinal materials extract content comparison of distinct methods

Under root of large-flowered skullcap item of Chinese pharmacopoeia version in 2010, Extract mensuration is measured, and the results are shown in Table 1.

Table 1 distinct methods is dried radix scutellariae medicinal materials extract content (%, n=3)

Medicinal material	Dry	After steaming, dry	Frozen steamed dries
				Extract content	42.7	45.9	57.43

Found out by table 1, the content of the root of large-flowered skullcap extract that frozen steamed dries is the highest.

Two, the dry radix scutellariae medicinal materials content of baicalin comparison of distinct methods

Under root of large-flowered skullcap item of Chinese pharmacopoeia version in 2010, content determination is measured, and the results are shown in Table 2.

Table 2 distinct methods is dried radix scutellariae medicinal materials content of baicalin (%)

Medicinal material	Dry	After steaming, dry	Frozen steamed dries
				Content of baicalin	11.3	14.6	18.7

Found out by table 2, the content of the root of large-flowered skullcap scutelloside that frozen steamed dries is the highest.

Three, the dry radix scutellariae medicinal materials quality stability comparison of distinct methods

Experimental condition: each sample is placed 12 months under 25 DEG C ± 2 DEG C of temperature, relative humidity 60 ± 10% conditions, in 0,3,6,9,12 month difference sampling and measuring content of baicalin, be the results are shown in Table 3.

Table 3 distinct methods is dried radix scutellariae medicinal materials quality stability result of the test

?	Dry	After steaming, dry	Frozen steamed dries
				0	11.3	14.6	18.7
3	11.1	14.6	18.8
				6	9.7	14.3	18.6
9	9.0	14.2	18.7
				12	8.1	14.3	18.7

Found out by table 3, after steaming, dry that to dry baicalin in Scutellaria baicalensis Georgi content high with frozen steamed, good stability.

Four, the dry radix scutellariae medicinal materials content of baicalin comparison of distinct methods after frozen steamed

To, with a collection of cadmium yellow a kind of reed mentioned in ancient books, remove impurity, be refrigerated to-5 DEG C with down to freezing, steam 15 minutes, vexed, be divided into 3 parts, to dry respectively, 60 DEG C of oven dry, dry.

Under root of large-flowered skullcap item of Chinese pharmacopoeia version in 2010, content determination is measured, and the results are shown in Table 4.

The dry content of baicalin (%) of distinct methods after table 4 frozen steamed

Medicinal material	Dry	60 DEG C of oven dry	Dry
				Content of baicalin	18.82	18.81	18.82

Found out by table 4, after frozen steamed, dry, 60 DEG C of oven dry, dry baicalin in Scutellaria baicalensis Georgi content basic identical.

Detailed description of the invention

embodiment 1

Get the fresh medicinal material of the root of large-flowered skullcap, remove impurity, be refrigerated to-5 DEG C to freezing, steam 15 minutes, vexed, dry.

embodiment 2

Get the fresh medicinal material of the root of large-flowered skullcap, remove impurity, be refrigerated to-15 DEG C to freezing, steam 5 minutes, vexed, dry.

embodiment 3

Get the fresh medicinal material of the root of large-flowered skullcap, remove impurity, be refrigerated to-5 DEG C to freezing, steam 13 minutes, vexed, dry.

embodiment 4

Get the fresh medicinal material of the root of large-flowered skullcap, remove impurity, be refrigerated to-20 DEG C to freezing, steam 10 minutes, vexed, dry;

embodiment 5

Get the fresh medicinal material of the root of large-flowered skullcap, remove impurity, be refrigerated to-30 DEG C to freezing, steam 20 minutes, vexed, 50 DEG C of oven dry.

Claims

1. a drying means for the root of large-flowered skullcap, is characterized in that: get cadmium yellow a kind of reed mentioned in ancient books, freezing, steaming is rear dry.

2. according to the drying means of a kind of root of large-flowered skullcap of claim 1, it is characterized in that: freezing is to be refrigerated to-5 DEG C with down to freezing, dry.

3. according to the drying means of a kind of root of large-flowered skullcap of claim 1, it is characterized in that: dry is dry or dry or dry after freezing.