CN104161995A - Bleeding stopping and blood coagulating powder used for traumatic hemorrhage and preparation method thereof - Google Patents
Bleeding stopping and blood coagulating powder used for traumatic hemorrhage and preparation method thereof Download PDFInfo
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- CN104161995A CN104161995A CN201410420130.0A CN201410420130A CN104161995A CN 104161995 A CN104161995 A CN 104161995A CN 201410420130 A CN201410420130 A CN 201410420130A CN 104161995 A CN104161995 A CN 104161995A
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Abstract
The invention provides bleeding stopping and blood coagulating powder used for traumatic hemorrhage and a preparation method thereof. The powder is prepared by mixing a component A and a component B, wherein the component A is prepared by drying and then grinding 7-9 parts of pseudo-ginseng, 2-3 parts of folium artemisiae argyi, 5-7 parts of common bletilla rubber, 3-5 parts of crinis carbonisatus, 1-2 parts of callicarpa macrophylla vahl, 1-2 parts of garden burnet root, 2-3 parts of agrimony and 4-6 parts of cacumen biotae in parts by weight; the component B is prepared by stir-frying and then grinding 8-9 parts of longan shells, 3-5 parts of Japanese thistle root, 5-7 parts of cattail pollen and 6-8 parts of ass hide glue in parts by weight. The powder has the beneficial effects that through reasonable compatibility of the medicinal materials with the functions of contracting blood vessels, increasing the number of blood platelets, improving the coagulation acceleration effects and inhibiting plasmin, blood coagulation is accelerated and wound healing is quickened; besides, the powder eliminates blood stasis inside wounds to some extent, is beneficial to bleeding stopping and avoids stasis.
Description
Technical field
The present invention relates to diagnosis and the treatment field of disease, specifically Trostin M blood powder and preparation method thereof for a kind of traumatic hemorrhage.
Background technology
Traumatic hemorrhage is with referring to that blood flows to body epigenesist from wound, is common in the wound of lancinating, stabs, gunshot wound and rolling, weighs wounded etc.If process not in time, can cause the series of problems such as wound infection, and then cause the healing time of wound to be delayed even leaving scar.
Summary of the invention
The object of this invention is to provide Trostin M blood powder and preparation method thereof for a kind of traumatic hemorrhage, when running into traumatic hemorrhage, this medicated powder is sprinkling upon on wound and with after sterilization cloth parcel, thereby can prevent wound infection, accelerate blood coagulation hemostasis accelerating wound, and, also eliminate to a certain extent the congestion of wound inside, prevent scar.
The present invention solves the problems of the technologies described above the technical scheme of employing to be: a kind of traumatic hemorrhage Trostin M blood powder, by component A and B component, mixed, according to weight ratio, described component A by 7-9 part Radix Notoginseng, 2-3 part Folium Artemisiae Argyi, 5-7 part Pseudobulbus Bletillae (Rhizoma Bletillae), 3-5 part Crinis Carbonisatus, 1-2 part Folium Callicarpae Formosanae, 1-2 part Radix Sanguisorbae, 2-3 part Herba Agrimoniae and 4-6 part Cacumen Platycladi, dried after pulverizing make, B component by 8-9 part longan shell, 3-5 part Radix Cirsii Japonici, 5-7 part Pollen Typhae and the parch of 6-8 part Colla Corii Asini after pulverizing form.
In described component A, also contain 3-5 part Flos Sophorae, 2-4 part Rhizoma Imperatae and 3-5 part Herba Cirsii.
The preparation method of Trostin M blood powder for above-mentioned traumatic hemorrhage, comprises the following steps:
1) according to above-mentioned requirements, take respectively each medical material of component A and B component;
2) each medical material in B component is cut into small pieces, then puts into the dry stir-fry of frying pan until then color blackening grinds to form fineness and be no more than 50 object fine powders, standby;
3) by wearing into fineness after each medical material oven dry in component A, be no more than 50 object fine powders, standby;
4) by step 2) and the fine powder mix homogeneously that makes of step 3) after obtain product.
Pharmacology and the property of medicine of the present invention's medical material used are as follows:
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature, return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel, there is the effect of loose blood, analgesic therapy.Be used for flutterring the diseases such as congestive edema, thoracic obstruction angor, lump in the abdomen, blood stasis amenorrhea;
Folium Artemisiae Argyi: acrid in the mouth, hardship, warm in nature, nontoxic; Return liver,spleen,kidney warp, have dispersing cold for relieving pain, the effect of warming the meridian for stopping bleeding.For few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spits blood, epistaxis, metrorrhagia warp is many, gestation hemorrhage;
Pseudobulbus Bletillae (Rhizoma Bletillae): acrid in the mouth, hardship, sweet, puckery, cold nature, returns lung, liver, stomach warp; It is active that the Pseudobulbus Bletillae (Rhizoma Bletillae) can strengthen platelet factor III, significantly shortens clotting time and thrombinogen formation time, suppresses plasmin enzymatic activity, and local hemorrhage is had to anastalsis; Zoopery shows, external Pseudobulbus Bletillae (Rhizoma Bletillae) haemostatic effect is quite good to parenchymatous organ's (liver, spleen), muscle vascular be hemorrhage etc. for Pseudobulbus Bletillae (Rhizoma Bletillae) water extraction.The styptic powder made from Pseudobulbus Bletillae (Rhizoma Bletillae), has good haemostatic effect to little angiorrbagia and the oozing of blood of the skin of some operation, flesh layer otch, better to the haemostatic effect after exodontia; But satisfied not to cutting off medium and small haemostatic effect quiet, tremulous pulse;
Crinis Carbonisatus: Chinese medicinal formulae, main component is a kind of eukerating, moisture content 12%-15%, ash 0.3%, fatty 3.4%-5.8%, nitrogen 17.4%, sulfur 5.00%, the another melanin (melanin) containing more or less.The effect that has repercussive, hemostasis.Control haematemesis, epistaxis, gingiva bleeding gingival hemorrhage, dysentery, stranguria with blood, metrorrhagia.And Crinis Carbonisatus has the effect of shortening the bleeding time and shrinking mucosa blood capillary;
Folium Callicarpae Formosanae: acrid in the mouth, hardship, property is flat, returns liver, spleen, stomach warp; There is dissipating blood stasis hemostasis, the effect of reducing swelling and alleviating pain.Leaf, for spitting blood, is spat blood, and epistaxis, has blood in stool; External curing traumatic hemorrhage; Root is for treating swelling and pain by traumatic injury, rheumatic ostalgia;
Radix Sanguisorbae: bitter in the mouth, acid, cold in nature, nontoxic, return liver, lung, kidney, large intestine channel; The effect that has cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore, cures mainly haematemesis, spitting of blood, and epistaxis, hematuria, has blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting;
Herba Agrimoniae: i.e. Western Agrimony, herb is robustness astringent hemostatic, has heart tonifying, rises blood pressure, blood coagulation, hemostasis, removing heat from blood, the effect such as antibacterial;
Cacumen Platycladi: be the browse of Cupressaceae plant Cacumen Platycladi, the effect that has hemostasis, black beard and hair, cough-relieving to breathe heavily.Bitter and puckery flavor, cold in nature, enter the heart, liver, large intestine channel, there is removing heat from blood, hemostasis, wind-damp dispelling, the effect of loose toxic swelling.Control haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, mumps, the diseases such as scald;
Longan shell: the shell that Arillus Longan is peeled off.
Radix Cirsii Japonici: cool in nature, sweet in the mouth, hardship, nontoxic, GUIXIN, Liver Channel, control haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer toxic swelling, the diseases such as furuncle.Zoopery shows: Radix Cirsii Japonici has facilitation to the coagulation process first stage (being the generation of thrombokinase), for hemorrhage due to bleeding due to blood-heat, and as haematemesis, epistaxis, metrorrhagia, hematuria etc., can single application or other hemorrhage of compatibility;
Pollen Typhae: sweet in the mouth, micro-pungent, property is flat, returns liver, the heart, spleen channel; There is the effect of hemostasis, blood stasis dispelling, diuresis; Cure mainly haematemesis; Spitting of blood; Epistaxis; Standby dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Trusted subordinate's pain; Amenorrhea stomachache; Puerperal stasis of blood pain; Dysmenorrhea; Tumbling and swelling; Blood strangury and dry pain; Leukorrhagia; Congenital deformity of the tongue; Aphtha; Ting ear; The uncontrolled urination disease such as itch;
Colla Corii Asini: for traditional nourishing, enrich blood top gradely, be to take donkey skin as primary raw material, put the water of A Jing and make (glue of not putting well water infusion is Colla Corii Asini, donkey glue).Have enrich blood, hemostasis, nourshing Yin and drynsessmoistening prescription effect;
Flos Sophorae: bitter in the mouth, cold nature, return liver, large intestine channel; There is cooling blood for hemostasis, purging liver-fire, enter blood and hold back and fall, the slight loose effect of body; Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia, spits blood, epistaxis, liver-fire headache, conjunctival congestion and swelling pain, sore throat, aphonia, the diseases such as ulcer sores;
Rhizoma Imperatae: cure mainly cooling blood for hemostasis, heat-clearing and toxic substances removing; For spitting blood, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, the gastric heat sound of vomiting of vomitting, coughs;
Herba Cirsii: sweet in the mouth, hardship, cool in nature.GUIXIN, Liver Channel.There is cooling blood for hemostasis, the effect of removing blood stasis to reduce swelling.For epistaxis, to spit blood, hematuria, has blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus etc.Herba Cirsii energy vasoconstrictive, increased platelets counts number, promotes platelet aggregation and increases thrombin activity, suppresses fibrinolytic, thereby accelerates hemostasis.Experiment in vitro shows, Herba Cirsii decoct has certain inhibitory action to diphtheria corynebacterium, streptococcus pneumoniae, Hemolytic streptococcus, staphylococcus aureus, bacillus pyocyaneus, Bacillus proteus, escherichia coli, Bacillus typhi etc.In addition, these product still can blood fat reducing, function of gallbladder promoting, diuresis, heart tonifying, boost etc.
Beneficial effect: the present invention has energy vasoconstrictive, increase number of platelets and coagulant effect by selecting, the medical material of inhibition plasmin effect carries out rational compatibility, thereby accelerated blood coagulation, accelerating wound, and, also eliminate to a certain extent the congestion of wound inside, be conducive to hemostasis and do not stay the stasis of blood.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated, and in the present invention, each medical material used all can be buied in pharmacy.
Embodiment 1
A kind of traumatic hemorrhage Trostin M blood powder, by component A and B component, mixed, according to weight ratio, described component A by 7 portions of Radix Notoginseng, 2 portions of Folium Artemisiae Argyis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Crinis Carbonisatus, 1 part of Folium Callicarpae Formosanae, 1 portion of Radix Sanguisorbae, 2 parts of Herba Agrimoniaes and 4 portions of Cacumen Platycladis, dried after pulverizing make, B component by 8 parts of longan shells, 3 portions of Radix Cirsii Japonicis, 5 parts of Pollen Typhaes and 6 parts of Colla Corii Asini parches after pulverizing form.
The preparation method of Trostin M blood powder for above-mentioned traumatic hemorrhage, comprises the following steps:
1) according to above-mentioned requirements, take respectively each medical material of component A and B component;
2) each medical material in B component is cut into small pieces, then puts into the dry stir-fry of frying pan until then color blackening grinds to form fineness and be no more than 50 object fine powders, standby;
3) by wearing into fineness after each medical material oven dry in component A, be no more than 50 object fine powders, standby;
4) by step 2) and the fine powder mix homogeneously that makes of step 3) after obtain product.
In order further to improve drug effect, in the present invention, can also in component A, add the Herba Cirsii of 3 parts of Flos Sophoraes, 2 parts of Rhizoma Imperataes and 3 parts.
Embodiment 2
A kind of traumatic hemorrhage Trostin M blood powder, by component A and B component, mixed, according to weight ratio, described component A by 9 portions of Radix Notoginseng, 3 portions of Folium Artemisiae Argyis, 7 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 5 parts of Crinis Carbonisatus, 2 parts of Folium Callicarpae Formosanae, 2 portions of Radix Sanguisorbaes, 3 parts of Herba Agrimoniaes and 6 portions of Cacumen Platycladis, dried after pulverizing make, B component by 9 parts of longan shells, 5 portions of Radix Cirsii Japonicis, 7 parts of Pollen Typhaes and 8 parts of Colla Corii Asini parches after pulverizing form.
The preparation method of Trostin M blood powder for above-mentioned traumatic hemorrhage, comprises the following steps:
1) according to above-mentioned requirements, take respectively each medical material of component A and B component;
2) each medical material in B component is cut into small pieces, then puts into the dry stir-fry of frying pan until then color blackening grinds to form fineness and be no more than 50 object fine powders, standby;
3) by wearing into fineness after each medical material oven dry in component A, be no more than 50 object fine powders, standby;
4) by step 2) and the fine powder mix homogeneously that makes of step 3) after obtain product.
In order further to improve drug effect, in the present invention, can also in component A, add the Herba Cirsii of 5 parts of Flos Sophoraes, 4 parts of Rhizoma Imperataes and 5 parts.
Embodiment 3
A kind of traumatic hemorrhage Trostin M blood powder, by component A and B component, mixed, according to weight ratio, described component A by 8 portions of Radix Notoginseng, 2.5 portions of Folium Artemisiae Argyis, 6 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 4 parts of Crinis Carbonisatus, 1.5 parts of Folium Callicarpae Formosanae, 1.5 portions of Radix Sanguisorbaes, 2.5 parts of Herba Agrimoniaes and 5 portions of Cacumen Platycladis, dried after pulverizing make, B component by 8.5 parts of longan shells, 4 portions of Radix Cirsii Japonicis, 6 parts of Pollen Typhaes and 7 parts of Colla Corii Asini parches after pulverizing form.
The preparation method of Trostin M blood powder for above-mentioned traumatic hemorrhage, comprises the following steps:
1) according to above-mentioned requirements, take respectively each medical material of component A and B component;
2) each medical material in B component is cut into small pieces, then puts into the dry stir-fry of frying pan until then color blackening grinds to form fineness and be no more than 50 object fine powders, standby;
3) by wearing into fineness after each medical material oven dry in component A, be no more than 50 object fine powders, standby;
4) by step 2) and the fine powder mix homogeneously that makes of step 3) after obtain product.
In order further to improve drug effect, the Herba Cirsii that can also add 3-5 part Flos Sophorae, 2-4 part Rhizoma Imperatae and 3-5 part in the present invention in component A.
By this product, for finding after zoopery, the phenomenon of bleeding that wound is caused has good hemostatic function, after find after being applied to use voluntarily the volunteer of this medicine, the traumatic hemorrhage that cutting, traumatic injury etc. are caused has good haemostatic effect.
Below by several model cases, the effect of product of the present invention is described:
Case 1, Wu so-and-so, 23 years old, female, in March, 2013 careless incised wound left index finger when cutting the dish, bled profusely at that time, after irrigating, used this product with clear water, and with gauze parcel, after three days, wound scabs, recovery from illness afterwards in seven days, stays without cicatrix;
Case 2, defend so-and-so, 13 years old, man, careless incised wound left index finger when pare an apple in October, 2013 with pocket knife, hemorrhage at that time, after irrigating with clear water, use this product, and with gauze parcel, wound scabs two days later, after recovery from illness, without cicatrix, stays;
Case 3, Zhang, 54 years old, female accidentally fell when get out of a predicament or an embarrassing situation in May, 2013, and left knee and palm all occur abrading hemorrhage, after irrigating, use this product with clear water, and wrap up with gauze, and wound scabs two days later, after recovery from illness, without cicatrix, stays;
Case 4, Zhang, 37 years old, female, in November, 2012 careless incised wound left hand when cutting the dish, bled profusely at that time, after irrigating, used this product with clear water, and wrapped up with gauze, and after three days, wound scabs, and after recovery from illness, without cicatrix, stays.
Claims (3)
1. a traumatic hemorrhage Trostin M blood powder, it is characterized in that: by component A and B component, mixed, according to weight ratio, described component A by 7-9 part Radix Notoginseng, 2-3 part Folium Artemisiae Argyi, 5-7 part Pseudobulbus Bletillae (Rhizoma Bletillae), 3-5 part Crinis Carbonisatus, 1-2 part Folium Callicarpae Formosanae, 1-2 part Radix Sanguisorbae, 2-3 part Herba Agrimoniae and 4-6 part Cacumen Platycladi, dried after pulverizing make, B component by 8-9 part longan shell, 3-5 part Radix Cirsii Japonici, 5-7 part Pollen Typhae and the parch of 6-8 part Colla Corii Asini after pulverizing form.
2. a kind of traumatic hemorrhage Trostin M blood powder according to claim 1, is characterized in that: in described component A, also contain 3-5 part Flos Sophorae, 2-4 part Rhizoma Imperatae and 3-5 part Herba Cirsii.
3. the preparation method of Trostin M blood powder for traumatic hemorrhage according to claim 1 and 2, is characterized in that, comprises the following steps:
1) according to the requirement of claim 1 or 2, take respectively each medical material of component A and B component;
2) each medical material in B component is cut into small pieces, then puts into the dry stir-fry of frying pan until then color blackening grinds to form fineness and be no more than 50 object fine powders, standby;
3) by wearing into fineness after each medical material oven dry in component A, be no more than 50 object fine powders, standby;
4) by step 2) and the fine powder mix homogeneously that makes of step 3) after obtain product.
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| CN105055642A (en) * | 2015-07-30 | 2015-11-18 | 上海宇昂新材料科技有限公司 | Compound guanidine disinfectant and preparation method of compound guanidine disinfectant |
| CN105311473A (en) * | 2015-11-27 | 2016-02-10 | 黄凤玲 | Rapid hemostasis drug |
| CN105381233A (en) * | 2015-11-10 | 2016-03-09 | 薛学明 | Medicine for in vitro hemostasis and preparation method of medicine |
| CN105617363A (en) * | 2016-02-29 | 2016-06-01 | 苏州市贝克生物科技有限公司 | Traditional Chinese medicine hemostatic powder and preparation method thereof |
| CN105797074A (en) * | 2016-04-27 | 2016-07-27 | 石建园 | External application medicament of traditional Chinese medicine composition for traumatic injuries as well as preparation method and application of external application medicament |
| CN105997185A (en) * | 2016-06-21 | 2016-10-12 | 山东大学齐鲁医院 | Elastic bleeding-stopping absorbent dressing fixing band |
| CN106266586A (en) * | 2015-05-27 | 2017-01-04 | 刘飞德 | The Chinese medicine composition of a kind of postoperation hemostatic sterilization and preparation and preparation method |
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| CN106798850A (en) * | 2017-02-16 | 2017-06-06 | 王宝磊 | A kind of Chinese medicine composition for emergency care traumatism and bleeding |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106266586A (en) * | 2015-05-27 | 2017-01-04 | 刘飞德 | The Chinese medicine composition of a kind of postoperation hemostatic sterilization and preparation and preparation method |
| CN105055642A (en) * | 2015-07-30 | 2015-11-18 | 上海宇昂新材料科技有限公司 | Compound guanidine disinfectant and preparation method of compound guanidine disinfectant |
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| CN105617363A (en) * | 2016-02-29 | 2016-06-01 | 苏州市贝克生物科技有限公司 | Traditional Chinese medicine hemostatic powder and preparation method thereof |
| CN105797074A (en) * | 2016-04-27 | 2016-07-27 | 石建园 | External application medicament of traditional Chinese medicine composition for traumatic injuries as well as preparation method and application of external application medicament |
| CN105997185A (en) * | 2016-06-21 | 2016-10-12 | 山东大学齐鲁医院 | Elastic bleeding-stopping absorbent dressing fixing band |
| CN106309016A (en) * | 2016-08-11 | 2017-01-11 | 鄢海军 | Comfortable polymolecular band aid |
| CN106729018A (en) * | 2016-12-08 | 2017-05-31 | 广西大学 | A kind of ointment of promotion blood clotting |
| CN106620350A (en) * | 2017-01-11 | 2017-05-10 | 韩秀霞 | Fast hemostatic patch for nursing in emergency department |
| CN106798850A (en) * | 2017-02-16 | 2017-06-06 | 王宝磊 | A kind of Chinese medicine composition for emergency care traumatism and bleeding |
| CN108186711A (en) * | 2017-02-27 | 2018-06-22 | 彭伟东 | Promote the pharmaceutical composition of wound healing |
| CN107468422A (en) * | 2017-08-30 | 2017-12-15 | 苏州市苏真床垫有限公司 | A kind of nursing pad for promoting wound healing |
| CN108310222A (en) * | 2018-05-08 | 2018-07-24 | 中国农业科学院特产研究所 | The fine and soft hemostatic traditional Chinese medicine composition of saw, preparation method and applications |
| CN108837173A (en) * | 2018-06-29 | 2018-11-20 | 首都医科大学附属北京世纪坛医院 | A kind of eccentric sexual oppression dressing and its production method being closed after treatment for vein |
| CN113171433A (en) * | 2021-06-09 | 2021-07-27 | 武汉市帆成丰硕生物科技有限公司 | Chinese medicinal composition preparation |
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Application publication date: 20141126 |