CN108837173A - A kind of eccentric sexual oppression dressing and its production method being closed after treatment for vein - Google Patents

A kind of eccentric sexual oppression dressing and its production method being closed after treatment for vein Download PDF

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Publication number
CN108837173A
CN108837173A CN201810714443.5A CN201810714443A CN108837173A CN 108837173 A CN108837173 A CN 108837173A CN 201810714443 A CN201810714443 A CN 201810714443A CN 108837173 A CN108837173 A CN 108837173A
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China
Prior art keywords
parts
portions
dressing
hemostatic
vein
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CN201810714443.5A
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Chinese (zh)
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牛鹿原
张欢
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Beijing Shijitan Hospital
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Beijing Shijitan Hospital
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Priority to CN201810714443.5A priority Critical patent/CN108837173A/en
Publication of CN108837173A publication Critical patent/CN108837173A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
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    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

The invention discloses the eccentric sexual oppression dressing after a kind of closure treatment for vein, are related to hemostatic material technical field, its key points of the technical solution are that including hemostatic gauze, hemostatic gauze includes fabric, the hemostatic agent being immersed in fabric and sterilizing medicament;The hemostatic agent is prepared by weight by following component:Tail 5-8 parts of Huanglong, 8-10 parts of iron amaranth grass, rich and honour 4-7 parts of dish, 5-9 parts of Seabuckthorn Oil, 3-6 parts of edetate sodium, 2-4 parts of Radix Notoginseng, 1-3 parts of aizoon stonecrop, 2.5-3.5 parts of saltcake, 1.5-2.5 parts of rheum officinale, 1-3 parts of sophora flower, 3-4 parts of hairyvein agrimony, 3-4 parts of folium artemisiae argyi, 1-3 parts of cattail pollen;The sterilizing medicament is prepared by weight by following component:9-11 parts of cassia bark, 5-9 parts of Swertia vacillana (Hance) Maxim., tail join 3-8 parts, 2-5 parts of the root of Dahurain angelica.The present invention solves the problems, such as that bleeding stopping period is long and wound is liable to infection, has achieved the effect that quick-acting haemostatic powder and sterilizing.

Description

A kind of eccentric sexual oppression dressing and its production method being closed after treatment for vein
Technical field
The present invention relates to hemostatic material in medical use technical fields, treat more specifically, it is related to a kind of be closed for vein Eccentric sexual oppression dressing and its production method afterwards.
Background technique
It needs to prick out blood outlet on the blood vessel of Venous leg varicose when treating varication, then covers hemostatic gauze On blood outlet, then varication socks are put on, hemostatic gauze, which is fixed on blood outlet, makes blood outlet heal.
In the prior art, it can refer to the Chinese invention patent file that Authorization Notice No. is CN103800940B, it discloses A kind of bleeding-stopping dressing and preparation method, include the following steps:Weigh mineral substance hemostasis granules, softening agent, adhesive, antibacterial material Material promotees coagulant material and water;Mineral substance hemostasis granules, softening agent, adhesive are added to the water mixing, boiled, it is cooling, suppression is added Bacterium material and rush coagulant material mix, and obtain hemostat suspension;By the hemostat suspension secure attachment in support matrix, do It is dry to get arrive a kind of bleeding-stopping dressing.
Existing this bleeding-stopping dressing using using mineral substance hemostasis granules as a part of hemostatic material, mineral substance Grain is bonded in support matrix under the action of adhesive, when mineral substance particle and wound contact, be easy to cause wound infection, because This needs produce it is a kind of can quick-acting haemostatic powder and be capable of sterilizing for the eccentric sexual oppression dressing after vein closure treatment And its production method.
Summary of the invention
In view of the deficiencies of the prior art, the present invention intends to provide it is a kind of for vein closure treatment after it is inclined Disposition oppresses dressing, is impregnated by the way that fabric to be placed in hemostatic agent and sterilizing medicament, can prepare fast short stopping Blood and the eccentric sexual oppression dressing being used for after vein closure treatment for capableing of sterilizing.
To achieve the above object, the present invention provides following technical solutions:A kind of bias being closed after treatment for vein Sexual oppression dressing, including hemostatic gauze, hemostatic gauze include fabric, the hemostatic agent being immersed in fabric and sterilizing medicine Agent;The mass ratio of the hemostatic agent and the sterilizing medicament is 1.3-1.5:0.6-0.9;The hemostatic agent be by with Lower ingredient is prepared by weight:Tail 5-8 parts of Huanglong, 8-10 parts of iron amaranth grass, rich and honour 4-7 parts of dish, 5-9 parts of Seabuckthorn Oil, according to ground Sour sodium 3-6 parts, 2-4 parts of Radix Notoginseng, 1-3 parts of aizoon stonecrop, 2.5-3.5 parts of saltcake, 1.5-2.5 parts of rheum officinale, 1-3 parts of sophora flower, red crowned crane 3-4 parts careless, 3-4 parts of folium artemisiae argyi, 1-3 parts of cattail pollen;The sterilizing medicament is prepared by weight by following component:Cassia bark 9-11 parts, 5-9 parts of Swertia vacillana (Hance) Maxim., 3-8 parts, 2-5 parts of the root of Dahurain angelica of tail ginseng.
By using above-mentioned technical proposal, contains agrimonine, agrimonolide, catechol etc. in Huanglong's tail, can contract Short blood clotting time increases blood platelet, promotes the generation of blood platelet and can increase blood calcium, has preferable quick-acting haemostatic powder to act on;Iron Amaranth grass can be clearing heat and detoxicating, cooling blood and hemostasis;Contain a large amount of phycocolloid element, mannitol, vitamin B, sulphur, potassium in the cauline leaf of rich and honour dish And the nutrients such as a variety of amino acid, have the function of preferably stopping blooding;Total seabuckthorn flavone in Seabuckthorn Oil can reduce high blood Rouge softens blood vessel, and can understand blood vessel deposit, removes the deposit of blood outlet clean;Radix Notoginseng, aizoon stonecrop It can make local vasoconstriction, have the effect of good hemostatic analgesia;Saltcake is used together with rheum officinale, can be clearing heat and detoxicating, Hemostasis convergence, swelling and pain relieving make wound fast convergence heal;Sophora flower chemical component containing there are many, wherein rutin and its glucoside are first Quercetin is able to maintain the normal resistance of capillary, reduces vasopermeability, can increase the elasticity of capillary, reach fast The blood vessel of short stopping blood;Hairyvein agrimony, folium artemisiae argyi and cattail pollen all have fast convergence hemostasis, shorten blood coagulation time, increase blood platelet Quantity, inhibits the activity of fibrinolysin, and anastalsis is preferable;Cassia bark is able to suppress growing for a variety of pathomycetes, can Sterilizing;Swertia vacillana (Hance) Maxim. has clearing heat and detoxicating, anti-inflammation and sterilization and other effects, can prevent blood outlet inflammation, inhibits bacterial growth;Tail Ginseng and the root of Dahurain angelica can antipyretic-antalgic, inhibit fungi to grow;There is the Huanglong's bone for shortening blood clotting time, iron amaranth grass, richness using a variety of Your dish etc., increases blood platelet, and the raw material of quick-acting haemostatic powder can make the outspoken short stopping blood of bleeding, and can restrain blood outlet, prevent again Secondary bleeding;Using cassia bark, Swertia vacillana (Hance) Maxim., tail ginseng and the root of Dahurain angelica, it is able to suppress bacterial growth, prevents blood outlet from infecting, promotes blood outlet Quickly healing.
The present invention is further arranged to:It further include scar agent of dispelling in the hemostatic gauze, scar agent and the hemostatic of dispelling The mass ratio of agent is 0.2-0.4:1.3-1.5, the scar agent of dispelling is prepared by weight by following component:Asparagus juice 4-9 Part, it is cactus juice 2-6 parts fresh, 1-4 parts of honey.
By using above-mentioned technical proposal, asparagus juice is rich in aloe-emodin and Anthraquinone Complex, applies in bleeding Blood outlet can be promoted to heal on mouthful, and make not stay scar at blood outlet;Cactus juice and honey being capable of sterilizations, reduction pain Bitterly, promote wound healing, prevent from infecting, prevent blood outlet from staying scar;Scar agent of dispelling is added in hemostatic gauze, wound can be promoted to be cured It closes, promotes myogenic growth, prevent blood outlet from staying scar.
The present invention is further arranged to:It further include analgestic in the hemostatic gauze, the analgestic and the hemostatic The mass ratio of agent is 0.1-0.2:1.3-1.5, the analgestic include 6-10 parts of vitamin B12,3-6 parts of borneol, olibanum 4-7 Part, 1-4 parts of bush.
By using above-mentioned technical proposal, borneol can clearing away heat to and alleviating pain, detumescence, erosion prevention and muscle growing, promote blood outlet convergence be cured It closes;Olibanum being capable of detumescence and promoting granulation, analgesic, convergence wound;Bush can reduce swelling, relieve pain;Analgestic, energy are added in hemostatic gauze The pain for enough mitigating patient, promotes the healing of wound.
The present invention is further arranged to:It further include consolidant in the hemostatic gauze, the consolidant and the hemostatic The mass ratio of agent is 0.3-0.5:1.3-1.5, the consolidant are prepared by weight by following component:Vitamin B2 4-8 parts, 5-10 parts of vitamin B6,4-9 parts of vitamin C.
By using above-mentioned technical proposal, cytothesis can be reduced swelling and be promoted to vitamin B2, promote the growth of skin, and Vitamin B6 is public, and effect is more preferable, and vitamin B6 can protect vascular endothelial cell, and vitamin C can maintain immune function, keeps Blood vessel is complete, blood outlet can be promoted to heal.
The present invention is further arranged to:It further include being wrapped in the mesh enclosure outside hemostatic gauze being used to prevent hemostatic gauze from scattering.
By using above-mentioned technical proposal, hemostatic gauze is wrapped in mesh enclosure, hemostatic gauze can be made more to concentrate deposited It at blood outlet, and will not scatter, quick-acting haemostatic powder is carried out to blood outlet convenient for hemostatic gauze.
The present invention is further arranged to:It is provided on the side that the mesh enclosure is contacted with the hemostatic gauze for by mesh enclosure The adhesive-layer being adhered on hemostatic gauze.
By using above-mentioned technical proposal, adhesive-layer of the mesh enclosure on hemostatic gauze side is set, net can be convenient for Hemostatic gauze is closely wrapped in mesh enclosure by cover, prevents from scattering in the use process of hemostatic gauze.
The present invention is further arranged to:The adhesive-layer is to be prepared by following component by mass parts:Hempleaf nettle root 4-6 Part, 5-8 parts of the bletilla striata, 2-3 parts of dandelion, 3-4 parts of Fructus Forsythiae, 1-3 parts of Lasiosphaera fenzlii.
By using above-mentioned technical proposal, dandelion, Fructus Forsythiae being capable of clearing heat and detoxicating, anti-inflammatory analgetics;Lasiosphaera fenzlii has apparent Haemostatic effect, and it is inhibited to pathomycete;The bletilla striata has effects that preferable astringing to arrest bleeding, detumescence and promoting granulation, may be used also To inhibit fungi to grow;Hempleaf nettle root has the function of analgesic, and hempleaf nettle root and the bletilla striata all have being a bit sticky, can be by mesh enclosure It is adhered on hemostatic gauze, prevents mesh enclosure from separating with hemostatic gauze, influence the use of hemostatic gauze.
The present invention is further arranged to:The mesh enclosure is made of elastic material.
By using above-mentioned technical proposal, the mesh enclosure made of elastic material has certain elasticity, can be packed into difference The hemostatic gauze of amount can be packed into hemostatic gauze according to the size of hemostatic port, avoid the waste of hemostatic gauze, can save hemostatic yarn The dosage of cloth.
In view of the deficienciess of the prior art, it is another object of the present invention to provide one kind for vein closure treatment The production method of eccentric sexual oppression dressing afterwards is closed the eccentricity after treatment for vein using what the production method processed Oppressing dressing being capable of quick-acting haemostatic powder and sterilizing.
To achieve the above object, the present invention provides following technical solutions:Include the following steps:
(1) taking total weight is 5-8 parts of Huanglong's tails, 8-10 parts of iron amaranths grass, 4-7 portion wealth and rank dishes, 5-9 parts of Seabuckthorn Oils and 3-6 parts according to ground Sour 3.5-4.7 times of sodium total weight of pure water simultaneously boils, and 5-8 parts of Huanglong's tails, 8-10 parts of iron amaranth grass, 4- are successively added into boiling water 7 portions of rich and honour dishes, 5-9 parts of Seabuckthorn Oils and 3-6 parts of edetate sodiums are decocted twice, are decocted 1-2 hours every time, merge decocting after decocting Liquid, and use filtering with microporous membrane;
(2) 2-4 portions of Radix Notoginseng, 1-3 portions of aizoon stonecrops, 2.5-3.5 parts of saltcake, 1.5-2.5 are added in gained filtrate into step (1) Part rheum officinale, 1-3 parts of sophoras flower, 3-4 portions of hairyvein agrimonies, 3-4 portions of folium artemisiae argyis, 1-3 parts of cattail pollens decoct once, and decocting time is 2-3 hours, With filtering with microporous membrane, filtrate is condensed into the medical fluid that relative density is 0.46, it is spare;
(3) taking gross mass is the pure water that 9-11 parts of cassia barks, the 2-5 parts of roots of Dahurain angelica, 3-8 parts of tails join 4.6-5.8 times of gross mass, to boiling Water in 9-11 part cassia barks, the 2-5 part roots of Dahurain angelica, 3-8 parts of tails are added join, and boil, add 5-9 parts of Swertia vacillana (Hance) Maxim., decoction three times, often Secondary decoction 2.5-3 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density be 0.43 Medical fluid, it is spare;
(4) 4-9 portions of asparagus juices are taken, are heated to 80-110 DEG C, under the revolving speed of 300-500 turns/min, are slowly added into asparagus juice Enter 2-6 parts of cactus juices, be warming up to 120-130 DEG C after mixing evenly, revolving speed is improved to 600-800 and turns/min, to mixed liquor 1-4 parts of honey of middle addition stir evenly, spare;
(5) 3-6 parts of borneols, 4-7 parts of olibanums, 1-4 portions of bushes and 6-10 parts of vitamin B12s are taken to carry out ball mill grinding, ratio of grinding media to material is 1.8:1, Ball-milling Time 20-60min, it is spare
(6) 4-8 parts of vitamin B2s, 5-10 parts of vitamin B6s and 4-9 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6: 1, Ball-milling Time 30-50min, it is spare;
(7) step (2) resulting liquid is heated to 100-120 DEG C, revolving speed be 200-300 turn/min under, by step (3) and Mixed powder obtained in the resulting liquid of step (4) and step (5) and step (6) sequentially adds step (2) resulting liquid In, room temperature is down to after keeping the temperature 20-30min;
It (8) is 1 by bath raio by fabric:30-50, which is placed in step (7) resulting mixed liquor, impregnates 40-60min, after dipping Fabric take out, be dehydrated 5-8min;
(9) fabric dewatered in step (8) placement is carried out disinfection under ultraviolet light, disinfecting time 20-30min;
(10) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
By using above-mentioned technical proposal, Huanglong's tail, iron amaranth grass, rich and honour dish, Seabuckthorn Oil and edetate sodium are first carried out pan-fried It boils, and decocts twice, the extract in each raw material can be extracted completely;It is added in the mixture in step (1) Radix Notoginseng etc., decocts again, and the extract of Huanglong's tail and Radix Notoginseng etc. can be made to be sufficiently mixed and be, and extracts complete;Because cassia bark, white It is withered that the root of Dahurian angelica and tail, which are proofread, it is difficult to it extracts, first boils cassia bark, the root of Dahurain angelica and tail ginseng in water, it can be convenient for extraction cassia bark, the root of Dahurain angelica With the extract in tail ginseng;Asparagus juice heating can be played the role of into sterilizing, cactus juice is added under stiring, it can It is uniformly mixed convenient for asparagus juice and cactus juice, because honey is more sticky, temperature is increased, can soften convenient for honey, mention High revolving speed can be convenient for for honey being uniformly mixed with the mixture of asparagus juice and cactus juice;Because borneol has volatility, easily Distillation;Olibanum preheating is easy softening;Vitamin B12 preheating has certain extent of the destruction, so can be incited somebody to action using ball mill grinding The grindings such as borneol, olibanum are thinner;Vitamin B2 is stable when heating and vitamin B6 is non-refractory, so using ball milling Pulverised form is ground;Finally resulting standby raw material is uniformly mixed, by the completely rear dehydration of fabric dipping, then ultraviolet light is carried out and kills Bacterium disinfection produces quick-acting haemostatic powder and is capable of controlling for vein closure for sterilizing finally by hemostatic gauze upper cover upper guard Eccentric sexual oppression dressing after treatment.
The present invention is further arranged to:Step (9) middle-ultraviolet lamp refers to C wave ultraviolet light, illumination wavelength 250- 270nm。
By using above-mentioned technical proposal, C wave ultraviolet light can result in that growth cell is extremely busy or regenerative cell is dead, Have the function that sterilizing, fabric is sterilized under the wavelength of 250-270nm, can sterilize more thoroughly.
In conclusion the present invention has the advantages that compared with the prior art:
(1) present invention is impregnated by the way that fabric to be placed in hemostatic agent and sterilizing medicament, can prepare quick-acting haemostatic powder And the eccentric sexual oppression dressing of sterilizing being used for after vein closure treatment;
(2) present invention can make bleeding by adding scar agent of dispelling in for the eccentric sexual oppression dressing after vein closure treatment Mouth preventing from scar;
(3) present invention can reduce trouble by adding analgestic in for the eccentric sexual oppression dressing after vein closure treatment The pain of person;
(4) present invention can promote by adding consolidant in for the eccentric sexual oppression dressing after vein closure treatment The healing of blood mouth, shortens healing time;
(5) hemostatic gauze is wrapped with mesh enclosure by preparation in hemostatic gauze upper cover upper guard, prevents hemostatic gauze by the present invention It scatters, the pressing for concentrating hemostatic gauze more is at blood outlet.
Specific embodiment
Embodiment 1:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:4 parts of hempleaf nettle roots, 5 portions of bletilla striatas, 2 portions of dandelions, 3 parts of Fructus Forsythiaes and 1 part of Lasiosphaera fenzlii.
Wherein hemostatic gauze includes hemostatic agent, the sterilizing medicament, scar of dispelling agent, analgesia of fabric, dipping on the fabric Agent and consolidant;Wherein the mass ratio of hemostatic agent, sterilizing medicament, scar of dispelling agent, analgestic and consolidant is 1.3:0.6: 0.2:0.1:0.3;
Hemostatic agent is to be prepared by following component by mass parts:5 parts of Huanglong's tails, 8 parts of iron amaranth grass, 4 portions of rich and honour dishes, 5 parts of sand Spine oil, 3 parts of edetate sodiums, 2 portions of Radix Notoginseng;1 portion of aizoon stonecrop;2.5 parts of saltcake;1.5 parts of rheum officinales, 1 part of sophora flower, 3 parts of hairyvein agrimonies, 3 Part folium artemisiae argyi and 1 part of cattail pollen;Sterilizing medicament is to be prepared by following component by mass parts:9 parts of cassia barks, 5 parts of Swertia vacillana (Hance) Maxim., 3 Part tail ginseng and 2 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:4 portions of asparagus juices, 2 parts of fresh cactus juices With 1 part of honey;Analgestic is to be prepared by following component by mass parts:6 parts of vitamin B12s, 3 parts of borneols, 4 parts of olibanums and 1 Part bush;Consolidant is to be prepared by following component by mass parts:4 parts of vitamin B2s, 5 parts of vitamin B6s and 4 parts of vitamins C。
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is 5 parts of Huanglong's tails, 8 parts of iron amaranth grass, 4 portions of rich and honour dishes, 5 parts of Seabuckthorn Oils and 3 parts of edetate sodium total weights 3.5 times of pure water simultaneously boils, be successively added into boiling water 5 parts of Huanglong's tails, 8 parts of iron amaranth grass, 4 portions of rich and honour dishes, 5 parts of Seabuckthorn Oils and 3 parts of edetate sodiums decoct twice, decoct 1 hour every time, merge the decocting liquid after decocting, and use filtering with microporous membrane;
(2) 2 portions of Radix Notoginseng, 1 portion of aizoon stonecrop, 2.5 parts of saltcake, 1.5 parts of rheum officinales, 1 portion of Chinese scholartree are added in gained filtrate into step (1) Flower, 3 portions of hairyvein agrimonies, 3 portions of folium artemisiae argyis, 1 part of cattail pollen decoct once, and decocting time is 2 hours, with filtering with microporous membrane, filtrate is dense Shorten the medical fluid that relative density is 0.46 into, it is spare;
(3) taking gross mass is the pure water that 9 parts of cassia barks, 2 parts of roots of Dahurain angelica, 3 parts of tails join 4.6 times of gross mass, is added 9 into the water boiled Part cassia bark, 2 parts of roots of Dahurain angelica, 3 parts of tails ginsengs, and boil, 5 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts 2.5 hours every time, merging is decocted Decocting liquid after boiling, and with filtering with microporous membrane, filtrate is condensed into the medical fluid that relative density is 0.43, it is spare;
(4) 4 portions of asparagus juices are taken, are heated to 80 DEG C, under the revolving speed of 300 turns/min, 2 portions of cactuses are slowly added into asparagus juice Juice is warming up to 120 DEG C after mixing evenly, and revolving speed is improved to 600 turns/min, 1 part of honey is added into mixed liquor and stirs evenly, It is spare;
(5) 3 parts of borneols, 4 parts of olibanums, 1 portion of bush and 6 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8:1, ball milling Time is 20min, spare;
(6) 4 parts of vitamin B2s, 5 parts of vitamin B6s and 4 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, when ball milling Between be 30min, it is spare;
(7) step (2) resulting liquid is heated to 100 DEG C, in the case where revolving speed is 200 turns/min, by step (3) and step (4) Mixed powder obtained in resulting liquid and step (5) and step (6) sequentially adds in step (2) resulting liquid, heat preservation Room temperature is down to after 20min;
It (8) is 1 by bath raio by fabric:30 are placed in step (7) resulting mixed liquor and impregnate 40min, by the fabric after dipping It takes out, is dehydrated 5min;
(9) dewatered fabric in step (8) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 250nm, disinfection Time 20min;
(10) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Embodiment 2:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in The mesh enclosure for being used to prevent hemostatic gauze from scattering outside hemostatic gauze;Mesh enclosure is made of elastic material;Mesh enclosure is contacted with hemostatic gauze The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer is by following component by mass parts It forms:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes hemostatic agent, the sterilizing medicament, scar of dispelling agent, analgesia of fabric, dipping on the fabric Agent and consolidant;Wherein the mass ratio of hemostatic agent, sterilizing medicament, scar of dispelling agent, analgestic and consolidant is 1.4:0.75: 0.3:0.15:0.4;
Hemostatic agent is to be prepared by following component by mass parts:6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 Part Seabuckthorn Oil, 4.5 parts of edetate sodiums, 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of red crowned cranes Grass, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens;Sterilizing medicament is to be prepared by following component by mass parts:10 parts of cassia barks, 7 portions of blueness Ye Dan, 5.5 parts of tail ginsengs and 3.5 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:6.5 portions of asparagus juices, 4 parts Fresh cactus juice and 2.5 parts of honey;Analgestic is to be prepared by following component by mass parts:8 parts of vitamin B12s, 4.5 parts Borneol, 5.5 parts of olibanums and 2.5 portions of bushes;Consolidant is to be prepared by following component by mass parts:6 parts of vitamin B2s, 7.5 Part vitamin B6 and 6.5 parts of vitamin Cs.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is that 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts of Seabuckthorn Oils and 4.5 parts of edetate sodiums are total The pure water that 4.1 times of weight simultaneously boils, and 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts are successively added into boiling water Seabuckthorn Oil and 4.5 parts of edetate sodiums decoct twice, decoct 1 every time.5 hours, merge the decocting liquid after decocting, and use miillpore filter Filtering;
(2) to be added in gained filtrate in step (1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens decoct once, and decocting time is 2.5 hours, with filtering with microporous membrane, will filter Liquid is condensed into the medical fluid that relative density is 0.46, spare;
(3) taking gross mass is the pure water that 10 parts of cassia barks, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tails join 5.2 times of gross mass, to the water boiled 10 parts of cassia barks of middle addition, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tail ginsengs, and boil, 7 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts every time 2.7 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density for 0.43 medical fluid, it is standby With;
(4) 6.5 portions of asparagus juices are taken, are heated to 95 DEG C, under the revolving speed of 400 turns/min, 4 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 125 DEG C after mixing evenly, revolving speed is improved to 700 turns/min, 2.5 parts of honey stirrings are added into mixed liquor Uniformly, spare;
(5) 4.5 parts of borneols, 5.5 parts of olibanums, 2.5 portions of bushes and 8 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8: 1, Ball-milling Time 40min, it is spare;
(6) 6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball Time consuming is 40min, spare;
(7) step (2) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (3) and step (4) Mixed powder obtained in resulting liquid and step (5) and step (6) sequentially adds in step (2) resulting liquid, heat preservation Room temperature is down to after 25min;
It (8) is 1 by bath raio by fabric:40 are placed in step (7) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(9) dewatered fabric in step (8) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(10) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Embodiment 3:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:6 parts of hempleaf nettle roots, 8 portions of bletilla striatas, 3 portions of dandelions, 4 parts of Fructus Forsythiaes and 3 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes hemostatic agent, the sterilizing medicament, scar of dispelling agent, analgesia of fabric, dipping on the fabric Agent and consolidant;Wherein the mass ratio of hemostatic agent, sterilizing medicament, scar of dispelling agent, analgestic and consolidant is 1.53:0.9: 0.4:0.2:0.5;
Hemostatic agent is to be prepared by following component by mass parts:8 parts of Huanglong's tails, 10 parts of iron amaranth grass, 7 portions of rich and honour dishes, 9 parts of sand Spine oil, 6 parts of edetate sodiums, 4 portions of Radix Notoginseng, 3 portions of aizoon stonecrops, 3.5 parts of saltcake, 2.5 parts of rheum officinales, 3 parts of sophoras flower, 4 parts of hairyvein agrimonies, 4 Part folium artemisiae argyi, 3 parts of cattail pollens;Sterilizing medicament is to be prepared by following component by mass parts:11 parts of cassia barks, 9 parts of Swertia vacillana (Hance) Maxim., 8 Part tail ginseng and 5 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:9 portions of asparagus juices, 6 parts of fresh cactus juices With 4 parts of honey;Analgestic is to be prepared by following component by mass parts:10 parts of vitamin B12s, 6 parts of borneols, 7 parts of olibanums and 4 Part bush;Consolidant is to be prepared by following component by mass parts:8 parts of vitamin B2s, 10 parts of vitamin B6s and 9 parts of vitamins C。
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is 8 parts of Huanglong's tails, 10 parts of iron amaranth grass, 7 portions of rich and honour dishes, 9 parts of Seabuckthorn Oils and 6 parts of edetate sodium total weights 4.7 times of pure water simultaneously boils, and 8 parts of Huanglong's tails, 10 parts of iron amaranth grass, 7 portions of rich and honour dishes, 9 parts of Seabuckthorn Oils are successively added into boiling water With 6 parts of edetate sodiums, decocts twice, decoct 2 hours every time, merge the decocting liquid after decocting, and use filtering with microporous membrane;
(2) 4 portions of Radix Notoginseng, 3 portions of aizoon stonecrops, 3.5 parts of saltcake, 2.5 parts of rheum officinales, 3 portions of Chinese scholartrees are added in gained filtrate into step (1) Flower, 4 portions of hairyvein agrimonies, 4 portions of folium artemisiae argyis, 3 parts of cattail pollens decoct once, and decocting time is 3 hours, with filtering with microporous membrane, filtrate is dense Shorten the medical fluid that relative density is 0.46 into, it is spare;
(3) taking gross mass is the pure water that 11 parts of cassia barks, 5 parts of roots of Dahurain angelica, 8 parts of tails join 5.8 times of gross mass, is added into the water boiled 11 parts of cassia barks, 5 parts of roots of Dahurain angelica, 8 parts of tail ginsengs, and boil, 9 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts 3 hours every time, merge and decoct Decocting liquid after boiling, and with filtering with microporous membrane, filtrate is condensed into the medical fluid that relative density is 0.43, it is spare;
(4) 9 portions of asparagus juices are taken, are heated to 110 DEG C, under the revolving speed of 500 turns/min, 6 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 130 DEG C after mixing evenly, revolving speed is improved to 800 turns/min, it is equal that 4 parts of honey stirrings are added into mixed liquor It is even, it is spare;
(5) 6 parts of borneols, 7 parts of olibanums, 4 portions of bushes and 10 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8:1, ball Time consuming is 60min, spare;
(6) 8 parts of vitamin B2s, 10 parts of vitamin B6s and 9 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball milling Time is 50min, spare;
(7) step (2) resulting liquid is heated to 120 DEG C, in the case where revolving speed is 300 turns/min, by step (3) and step (4) Mixed powder obtained in resulting liquid and step (5) and step (6) sequentially adds in step (2) resulting liquid, heat preservation Room temperature is down to after 30min;
It (8) is 1 by bath raio by fabric:50 are placed in step (7) resulting mixed liquor and impregnate 60min, by the fabric after dipping It takes out, is dehydrated 8min;
(9) dewatered fabric in step (8) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 270nm, disinfection Time 30min;
(10) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Comparative example 1:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes fabric, sterilizing medicament, scar of dispelling agent, analgestic and the healing of dipping on the fabric Agent;Wherein the mass ratio of sterilizing medicament, scar of dispelling agent, analgestic and consolidant is 0.75:0.3:0.15:0.4;
Sterilizing medicament is to be prepared by following component by mass parts:10 parts of cassia barks, 7 parts of Swertia vacillana (Hance) Maxim., 5.5 parts of tails ginseng and 3.5 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:6.5 portions of asparagus juices, 4 parts of fresh cactus juices and 2.5 Part honey;Analgestic is to be prepared by following component by mass parts:8 parts of vitamin B12s, 4.5 parts of borneols, 5.5 parts of olibanums and 2.5 portions of bushes;Consolidant is to be prepared by following component by mass parts:6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts Vitamin C.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 are taken Part cattail pollen decocts once, and decocting time is 2.5 hours, and with filtering with microporous membrane, it is 0.46 that filtrate, which is condensed into relative density, Medical fluid, it is spare;
(2) taking gross mass is the pure water that 10 parts of cassia barks, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tails join 5.2 times of gross mass, to the water boiled 10 parts of cassia barks of middle addition, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tail ginsengs, and boil, 7 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts every time 2.7 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density for 0.43 medical fluid, it is standby With;
(3) 6.5 portions of asparagus juices are taken, are heated to 95 DEG C, under the revolving speed of 400 turns/min, 4 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 125 DEG C after mixing evenly, revolving speed is improved to 700 turns/min, 2.5 parts of honey stirrings are added into mixed liquor Uniformly, spare;
(4) 4.5 parts of borneols, 5.5 parts of olibanums, 2.5 portions of bushes and 8 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8: 1, Ball-milling Time 40min, it is spare;
(5) 6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball Time consuming is 40min, spare;
(6) step (1) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (2) and step (3) Mixed powder obtained in resulting liquid and step (4) and step (5) sequentially adds in step (1) resulting liquid, heat preservation Room temperature is down to after 25min;
It (7) is 1 by bath raio by fabric:40 are placed in step (6) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(8) dewatered fabric in step (7) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(9) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Comparative example 2:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes fabric, hemostatic agent, scar of dispelling agent, analgestic and the consolidant of dipping on the fabric;Its Middle hemostatic agent, scar of dispelling agent, analgestic and consolidant mass ratio be 1.4:0.3:0.15:0.4;
Hemostatic agent is to be prepared by following component by mass parts:6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 Part Seabuckthorn Oil, 4.5 parts of edetate sodiums, 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of red crowned cranes Grass, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens;Scar of dispelling agent is to be prepared by following component by mass parts:6.5 portions of asparagus juices, 4 parts it is fresh Cactus juice and 2.5 parts of honey;Analgestic is to be prepared by following component by mass parts:8 parts of vitamin B12s, 4.5 parts of ice Piece, 5.5 parts of olibanums and 2.5 portions of bushes;Consolidant is to be prepared by following component by mass parts:6 parts of vitamin B2s, 7.5 parts Vitamin B6 and 6.5 parts of vitamin Cs.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is that 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts of Seabuckthorn Oils and 4.5 parts of edetate sodiums are total The pure water that 4.1 times of weight simultaneously boils, and 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts are successively added into boiling water Seabuckthorn Oil and 4.5 parts of edetate sodiums decoct twice, decoct 1 every time.5 hours, merge the decocting liquid after decocting, and use miillpore filter Filtering;
(2) to be added in gained filtrate in step (1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens decoct once, and decocting time is 2.5 hours, with filtering with microporous membrane, will filter Liquid is condensed into the medical fluid that relative density is 0.46, spare;
(3) 6.5 portions of asparagus juices are taken, are heated to 95 DEG C, under the revolving speed of 400 turns/min, 4 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 125 DEG C after mixing evenly, revolving speed is improved to 700 turns/min, 2.5 parts of honey stirrings are added into mixed liquor Uniformly, spare;
(4) 4.5 parts of borneols, 5.5 parts of olibanums, 2.5 portions of bushes and 8 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8: 1, Ball-milling Time 40min, it is spare;
(5) 6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball Time consuming is 40min, spare;
(6) step (2) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (3) resulting liquid Mixed powder obtained in body and step (4) and step (5) sequentially adds in step (2) resulting liquid, after keeping the temperature 25min It is down to room temperature;
It (7) is 1 by bath raio by fabric:40 are placed in step (6) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(8) dewatered fabric in step (7) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(9) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Comparative example 3:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes fabric, hemostatic agent, sterilizing medicament, analgestic and the healing of dipping on the fabric Agent;Wherein the mass ratio of hemostatic agent, sterilizing medicament, analgestic and consolidant is 1.4:0.75:0.15:0.4;
Hemostatic agent is to be prepared by following component by mass parts:6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 Part Seabuckthorn Oil, 4.5 parts of edetate sodiums, 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of red crowned cranes Grass, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens;Sterilizing medicament is to be prepared by following component by mass parts:10 parts of cassia barks, 7 portions of blueness Ye Dan, 5.5 parts of tail ginsengs and 3.5 parts of roots of Dahurain angelica;Analgestic is to be prepared by following component by mass parts:8 parts of vitamin B12s, 4.5 Part borneol, 5.5 parts of olibanums and 2.5 portions of bushes;Consolidant is to be prepared by following component by mass parts:6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is that 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts of Seabuckthorn Oils and 4.5 parts of edetate sodiums are total The pure water that 4.1 times of weight simultaneously boils, and 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts are successively added into boiling water Seabuckthorn Oil and 4.5 parts of edetate sodiums decoct twice, decoct 1 every time.5 hours, merge the decocting liquid after decocting, and use miillpore filter Filtering;
(2) to be added in gained filtrate in step (1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens decoct once, and decocting time is 2.5 hours, with filtering with microporous membrane, will filter Liquid is condensed into the medical fluid that relative density is 0.46, spare;
(3) taking gross mass is the pure water that 10 parts of cassia barks, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tails join 5.2 times of gross mass, to the water boiled 10 parts of cassia barks of middle addition, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tail ginsengs, and boil, 7 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts every time 2.7 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density for 0.43 medical fluid, it is standby With;
(4) 4.5 parts of borneols, 5.5 parts of olibanums, 2.5 portions of bushes and 8 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8: 1, Ball-milling Time 40min, it is spare;
(5) 6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball Time consuming is 40min, spare;
(6) step (2) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (3) resulting liquid Mixed powder obtained in body and step (4) and step (5) sequentially adds in step (2) resulting liquid, after keeping the temperature 25min It is down to room temperature;
It (7) is 1 by bath raio by fabric:40 are placed in step (6) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(8) dewatered fabric in step (7) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(9) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Comparative example 4:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes hemostatic agent, the sterilizing medicament, scar of dispelling agent, analgesia of fabric, dipping on the fabric Agent and consolidant;Wherein hemostatic agent, sterilizing medicament, scar of dispelling agent, consolidant mass ratio be 1.4:0.75:0.3:0.4;
Hemostatic agent is to be prepared by following component by mass parts:6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 Part Seabuckthorn Oil, 4.5 parts of edetate sodiums, 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of red crowned cranes Grass, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens;Sterilizing medicament is to be prepared by following component by mass parts:10 parts of cassia barks, 7 portions of blueness Ye Dan, 5.5 parts of tail ginsengs and 3.5 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:6.5 portions of asparagus juices, 4 parts Fresh cactus juice and 2.5 parts of honey;Consolidant is to be prepared by following component by mass parts:6 parts of vitamin B2s, 7.5 parts Vitamin B6 and 6.5 parts of vitamin Cs.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is that 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts of Seabuckthorn Oils and 4.5 parts of edetate sodiums are total The pure water that 4.1 times of weight simultaneously boils, and 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts are successively added into boiling water Seabuckthorn Oil and 4.5 parts of edetate sodiums decoct twice, decoct 1 every time.5 hours, merge the decocting liquid after decocting, and use miillpore filter Filtering;
(2) to be added in gained filtrate in step (1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens decoct once, and decocting time is 2.5 hours, with filtering with microporous membrane, will filter Liquid is condensed into the medical fluid that relative density is 0.46, spare;
(3) taking gross mass is the pure water that 10 parts of cassia barks, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tails join 5.2 times of gross mass, to the water boiled 10 parts of cassia barks of middle addition, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tail ginsengs, and boil, 7 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts every time 2.7 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density for 0.43 medical fluid, it is standby With;
(4) 6.5 portions of asparagus juices are taken, are heated to 95 DEG C, under the revolving speed of 400 turns/min, 4 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 125 DEG C after mixing evenly, revolving speed is improved to 700 turns/min, 2.5 parts of honey stirrings are added into mixed liquor Uniformly, spare;
(5) 6 parts of vitamin B2s, 7.5 parts of vitamin B6s and 6.5 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6:1, ball Time consuming is 40min, spare;
(6) step (2) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (3) and step (4) Mixed powder obtained in resulting liquid and step (5) sequentially adds in step (2) resulting liquid, drops after keeping the temperature 25min To room temperature;
It (7) is 1 by bath raio by fabric:40 are placed in step (6) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(8) dewatered fabric in step (7) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(9) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
Comparative example 5:A kind of eccentric sexual oppression dressing after the closure treatment for vein, including hemostatic gauze and be wrapped in only The mesh enclosure for being used to prevent hemostatic gauze from scattering outside blood gauze;Mesh enclosure is made of elastic material;Mesh enclosure contacted with hemostatic gauze one The adhesive-layer for being adhered to hemostatic gauze on hemostatic gauze is provided on side;Adhesive-layer be by following component by mass parts and At:5 parts of hempleaf nettle roots, 6.5 portions of bletilla striatas, 2.5 portions of dandelions, 3.5 parts of Fructus Forsythiaes and 2 parts of Lasiosphaera fenzliis.
Wherein hemostatic gauze includes hemostatic agent, the sterilizing medicament, scar of dispelling agent, analgesia of fabric, dipping on the fabric Agent and consolidant;Wherein hemostatic agent, sterilizing medicament, scar of dispelling agent, analgestic mass ratio be 1.4:0.75:0.3: 0.15;
Hemostatic agent is to be prepared by following component by mass parts:6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 Part Seabuckthorn Oil, 4.5 parts of edetate sodiums, 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of red crowned cranes Grass, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens;Sterilizing medicament is to be prepared by following component by mass parts:10 parts of cassia barks, 7 portions of blueness Ye Dan, 5.5 parts of tail ginsengs and 3.5 parts of roots of Dahurain angelica;Scar of dispelling agent is to be prepared by following component by mass parts:6.5 portions of asparagus juices, 4 parts Fresh cactus juice and 2.5 parts of honey;Analgestic is to be prepared by following component by mass parts:8 parts of vitamin B12s, 4.5 parts Borneol, 5.5 parts of olibanums and 2.5 portions of bushes.
The production method of the eccentric sexual oppression dressing being used for after vein closure treatment includes the following steps:
(1) taking total weight is that 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts of Seabuckthorn Oils and 4.5 parts of edetate sodiums are total The pure water that 4.1 times of weight simultaneously boils, and 6.5 parts of Huanglong's tails, 9 parts of iron amaranth grass, 5.5 portions of rich and honour dishes, 7 parts are successively added into boiling water Seabuckthorn Oil and 4.5 parts of edetate sodiums decoct twice, decoct 1 every time.5 hours, merge the decocting liquid after decocting, and use miillpore filter Filtering;
(2) to be added in gained filtrate in step (1) 3 portions of Radix Notoginseng, 2 portions of aizoon stonecrops, 3 parts of saltcake, 2 parts of rheum officinales, 2 parts of sophoras flower, 3.5 portions of hairyvein agrimonies, 3.5 portions of folium artemisiae argyis and 2 parts of cattail pollens decoct once, and decocting time is 2.5 hours, with filtering with microporous membrane, will filter Liquid is condensed into the medical fluid that relative density is 0.46, spare;
(3) taking gross mass is the pure water that 10 parts of cassia barks, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tails join 5.2 times of gross mass, to the water boiled 10 parts of cassia barks of middle addition, 3.5 parts of roots of Dahurain angelica and 5.5 parts of tail ginsengs, and boil, 7 parts of Swertia vacillana (Hance) Maxim. are added, decocts three times, decocts every time 2.7 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density for 0.43 medical fluid, it is standby With;
(4) 6.5 portions of asparagus juices are taken, are heated to 95 DEG C, under the revolving speed of 400 turns/min, 4 parts of celestial beings are slowly added into asparagus juice Juice is slapped, is warming up to 125 DEG C after mixing evenly, revolving speed is improved to 700 turns/min, 2.5 parts of honey stirrings are added into mixed liquor Uniformly, spare;
(5) 4.5 parts of borneols, 5.5 parts of olibanums, 2.5 portions of bushes and 8 parts of vitamin B12s is taken to carry out ball mill grinding, ratio of grinding media to material 1.8: 1, Ball-milling Time 40min, it is spare;
(6) step (2) resulting liquid is heated to 110 DEG C, in the case where revolving speed is 250 turns/min, by step (3) and step (4) Mixed powder obtained in resulting liquid and step (5) sequentially adds in step (2) resulting liquid, drops after keeping the temperature 25min To room temperature;
It (7) is 1 by bath raio by fabric:40 are placed in step (6) resulting mixed liquor and impregnate 50min, by the fabric after dipping It takes out, is dehydrated 6.5min;
(8) dewatered fabric in step (7) is placed under C wave ultraviolet light and is carried out disinfection, illumination wavelength 260nm, disinfection Time 25min;
(9) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
The dosage of each ingredient is as shown in table 1 in each embodiment and each comparative example:
Each Ingredient Amount table in each embodiment of table 1 and each comparative example
Hemostasis experiment:Experimental rabbit is equally divided into 7 groups, including embodiment 1-2 and comparative example 1-5, experimental rabbit ear is lost hair or feathers, It sterilizes, under aseptic condition at rabbit ear edge end 1/3, the blood outlet of 1cm long is cut with sterile surgical knife, including ear center One aorta is cut open, but ear is not thorough, and anti-Hemostatic Oral Liquid is flowed out from inside, carries out subsequent blood coagulation after blood is full of the surface of a wound Test weighs the quality (m for the eccentric sexual oppression dressing after vein closure treatment1), hemostasis is crushed, takes away and is used for after 10s Eccentric sexual oppression dressing after vein closure treatment, observes haemostatic effect.When no more blood record when flowing out from blood outlet Between T1, every 5s observation is primary later, until hemostasis completely, records time T2, bleeding stopping period T1And T2Average value.Stop blooding Cheng Hou weighs the quality (m for the eccentric sexual oppression dressing after vein closure treatment of sucking blood2), calculate amount of bleeding m= m2-m1
Healing Experiments:Mouse is equally divided into 7 groups, including embodiment 1-2 and comparative example 1-5, with 3% yellow Jackets 30mg/kg intraperitoneal injection anesthesia, back of mice backbone two sides are lost hair or feathers, and lose hair or feathers area 4cm2, hair removal section is scalded with boiled water, With for the eccentric sexual oppression dressing wound coverage face after vein closure treatment, daily dressing is primary.
Performance indexes of the table 1 for the eccentric sexual oppression dressing after vein closure treatment
By being used for the performance indexes of the eccentric sexual oppression dressing after vein closure is treated in table 1 it is found that adding in embodiment 1-3 Add hemostatic agent, sterilizing medicament, scar of dispelling agent, analgestic and consolidant, shortens the bleeding time, reduce amount of bleeding, is noninductive Contaminate phenomenon, without scar, without lather phenomenon and healing time it is short;In comparative example 1 without Huanglong's tail, iron amaranth grass, rich and honour dish, Seabuckthorn Oil, edetate sodium, bleeding stopping period is significantly longer, and amount of bleeding is larger;Sterilizing medicament in comparative example 2 goes out at blood outlet Existing infection phenomenons;Without dispelling scar agent in comparative example 3, there are scars at blood outlet;Without analgestic in comparative example 4;Rabbit and mouse go out Now serious lather phenomenon;Without consolidant in comparative example 5, the healing time of mouse wound face is longer;Therefore Huanglong's tail, iron amaranth Grass, rich and honour dish, Seabuckthorn Oil, edetate sodium can shorten bleeding stopping period, reduce amount of bleeding;Sterilizing medicament is able to suppress bacterium It grows, uses wound face without infection phenomenons;Scar of dispelling agent can erosion prevention and muscle growing, make wound face without scar;Analgestic can reduce swelling only Bitterly;Consolidant can promote wound healing, shorten healing time.
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications It should be regarded as protection scope of the present invention.

Claims (10)

1. the eccentric sexual oppression dressing after a kind of closure treatment for vein, it is characterised in that:Including hemostatic gauze, hemostatic gauze Including fabric, the hemostatic agent being immersed in fabric and sterilizing medicament;
The mass ratio of the hemostatic agent and the sterilizing medicament is 1.3-1.5:0.6-0.9;
The hemostatic agent is prepared by weight by following component:Tail 5-8 parts of Huanglong, 8-10 parts of iron amaranth grass, rich and honour dish 4-7 parts, 5-9 parts of Seabuckthorn Oil, 3-6 parts of edetate sodium, 2-4 parts of Radix Notoginseng, 1-3 parts of aizoon stonecrop, 2.5-3.5 parts of saltcake, rheum officinale 1.5-2.5 parts, 1-3 parts of sophora flower, 3-4 parts of hairyvein agrimony, 3-4 parts of folium artemisiae argyi, 1-3 parts of cattail pollen;
The sterilizing medicament is prepared by weight by following component:9-11 parts of cassia bark, 5-9 parts of Swertia vacillana (Hance) Maxim., tail ginseng 3-8 parts, 2-5 parts of the root of Dahurain angelica.
2. the eccentric sexual oppression dressing after the closure treatment according to claim 1 for vein, it is characterised in that:It is described to stop It further include scar agent of dispelling in blood gauze, the mass ratio of dispel scar agent and the hemostatic agent is 0.2-0.4:1.3-1.5 described dispel Scar agent is prepared by weight by following component:4-9 parts of asparagus juice, it is cactus juice 2-6 parts fresh, 1-4 parts of honey.
3. the eccentric sexual oppression dressing after the closure treatment according to claim 1 for vein, it is characterised in that:It is described to stop It further include analgestic in blood gauze, the mass ratio of the analgestic and the hemostatic agent is 0.1-0.2:1.3-1.5 the town Pain agent includes 6-10 parts of vitamin B12,3-6 parts of borneol, 4-7 parts of olibanum, 1-4 parts of bush.
4. the eccentric sexual oppression dressing after the closure treatment according to claim 1 for vein, it is characterised in that:It is described to stop It further include consolidant in blood gauze, the mass ratio of the consolidant and the hemostatic agent is 0.3-0.5:1.3-1.5 described be cured Mixture is prepared by weight by following component:4-8 parts of vitamin B2,5-10 parts of vitamin B6, vitamin C 4-9 Part.
5. the eccentric sexual oppression dressing after the closure treatment according to claim 1 for vein, it is characterised in that:Further include It is wrapped in the mesh enclosure outside hemostatic gauze being used to prevent hemostatic gauze from scattering.
6. the eccentric sexual oppression dressing after the closure treatment according to claim 5 for vein, it is characterised in that:The net Cover the adhesive-layer being provided on the side contacted with the hemostatic gauze for being adhered to mesh enclosure on hemostatic gauze.
7. the eccentric sexual oppression dressing after the closure treatment according to claim 6 for vein, it is characterised in that:It is described viscous Glue-line is to be prepared by following component by mass parts:4-6 parts of hempleaf nettle root, 5-8 parts of the bletilla striata, 2-3 parts of dandelion, 3-4 parts of Fructus Forsythiae, 1-3 parts of Lasiosphaera fenzlii.
8. the eccentric sexual oppression dressing after the closure treatment according to claim 5 for vein, it is characterised in that:The net Cover is made of elastic material.
9. a kind of production of the eccentric sexual oppression dressing after closure treatment according to claim 1-8 for vein Method, it is characterised in that:Include the following steps:
(1) taking total weight is 5-8 parts of Huanglong's tails, 8-10 parts of iron amaranths grass, 4-7 portion wealth and rank dishes, 5-9 parts of Seabuckthorn Oils and 3-6 parts according to ground Sour 3.5-4.7 times of sodium total weight of pure water simultaneously boils, and 5-8 parts of Huanglong's tails, 8-10 parts of iron amaranth grass, 4- are successively added into boiling water 7 portions of rich and honour dishes, 5-9 parts of Seabuckthorn Oils and 3-6 parts of edetate sodiums are decocted twice, are decocted 1-2 hours every time, merge decocting after decocting Liquid, and use filtering with microporous membrane;
(2) 2-4 portions of Radix Notoginseng, 1-3 portions of aizoon stonecrops, 2.5-3.5 parts of saltcake, 1.5-2.5 are added in gained filtrate into step (1) Part rheum officinale, 1-3 parts of sophoras flower, 3-4 portions of hairyvein agrimonies, 3-4 portions of folium artemisiae argyis, 1-3 parts of cattail pollens decoct once, and decocting time is 2-3 hours, With filtering with microporous membrane, filtrate is condensed into the medical fluid that relative density is 0.46, it is spare;
(3) taking gross mass is the pure water that 9-11 parts of cassia barks, the 2-5 parts of roots of Dahurain angelica, 3-8 parts of tails join 4.6-5.8 times of gross mass, to boiling Water in 9-11 part cassia barks, the 2-5 part roots of Dahurain angelica, 3-8 parts of tails are added join, and boil, add 5-9 parts of Swertia vacillana (Hance) Maxim., decoction three times, often Secondary decoction 2.5-3 hours, merge decoct after decocting liquid, and use filtering with microporous membrane, by filtrate be condensed into relative density be 0.43 Medical fluid, it is spare;
(4) 4-9 portions of asparagus juices are taken, are heated to 80-110 DEG C, under the revolving speed of 300-500 turns/min, are slowly added into asparagus juice Enter 2-6 parts of cactus juices, be warming up to 120-130 DEG C after mixing evenly, revolving speed is improved to 600-800 and turns/min, to mixed liquor 1-4 parts of honey of middle addition stir evenly, spare;
(5) 3-6 parts of borneols, 4-7 parts of olibanums, 1-4 portions of bushes and 6-10 parts of vitamin B12s are taken to carry out ball mill grinding, ratio of grinding media to material is 1.8:1, Ball-milling Time 20-60min, it is spare
(6) 4-8 parts of vitamin B2s, 5-10 parts of vitamin B6s and 4-9 parts of vitamin Cs is taken to carry out ball mill grinding, ratio of grinding media to material 1.6: 1, Ball-milling Time 30-50min, it is spare;
(7) step (2) resulting liquid is heated to 100-120 DEG C, revolving speed be 200-300 turn/min under, by step (3) and Mixed powder obtained in the resulting liquid of step (4) and step (5) and step (6) sequentially adds step (2) resulting liquid In, room temperature is down to after keeping the temperature 20-30min;
It (8) is 1 by bath raio by fabric:30-50, which is placed in step (7) resulting mixed liquor, impregnates 40-60min, after dipping Fabric take out, be dehydrated 5-8min;
(9) fabric dewatered in step (8) placement is carried out disinfection under ultraviolet light, disinfecting time 20-30min;
(10) adhesive-layer will be smeared on fabric, mesh enclosure set is obtained to the eccentricity pressure after being used for vein closure treatment on the fabric Compel dressing.
10. the production method of the eccentric sexual oppression dressing after the closure treatment according to claim 9 for vein, feature It is:Step (9) middle-ultraviolet lamp refers to C wave ultraviolet light, illumination wavelength 250-270nm.
CN201810714443.5A 2018-06-29 2018-06-29 A kind of eccentric sexual oppression dressing and its production method being closed after treatment for vein Pending CN108837173A (en)

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