CN101732567B - Medicament for treating burns and preparation method thereof - Google Patents

Medicament for treating burns and preparation method thereof Download PDF

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CN101732567B
CN101732567B CN200810143727XA CN200810143727A CN101732567B CN 101732567 B CN101732567 B CN 101732567B CN 200810143727X A CN200810143727X A CN 200810143727XA CN 200810143727 A CN200810143727 A CN 200810143727A CN 101732567 B CN101732567 B CN 101732567B
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burn
medicament
ethanol
medicine
burns
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CN101732567A (en
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吴国传
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ZOU XIQUN
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ZOU XIQUN
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Abstract

The invention discloses a medicament for treating burns and a preparation method thereof. In order to overcome the defects of slow response, weak pain ease, scar after curing, need of skin grafting and the like of the conventional medicament for treating the burns, the medicament takes the following components as raw materials: bezoar, musk, pangolin scales, giant knotweed, goldthread root, amur corktree bark, rhubarb, airpotato yam rhizome, bletilla, Japanese ampelopsis root, Chinese angelica, chrysanthemum, lindley eupatorium herb, Chinese loropetalum herb, Chinese arborvitae twig, liquoricroot, cattle horn, 55 percent ethanol, parabens and mountain water. The medicament is prepared by processing the rest components except the bezoar, the musk, the chrysanthemum, the 55 percent ethanoland methyl hydroxybenzoate respectively by a conventional processing method of Chinese medicaments, crushing, mixing and fermenting the rest components except the bezoar, the musk, the 55 percent ethanol and the methyl hydroxybenzoate, distilling the fermented materials, adding the bezoar, the musk, the 55 percent ethanol and the methyl hydroxybenzoate into the distilled materials, and uniformly stirring and bottling the mixture serving as spray and liniment for the burns. The medicament is used for treating the burns, scalds, caumas, explosive wounds and the like, and has the advantages of quick response, strong effects of killing pain, no scar after curing, and no need of skin grafting.

Description

Medicine and the compound method thereof for the treatment of burn
Technical field
The present invention relates to a kind of medicine for the treatment of burn, be specially a kind of medicine of the treatment burn take Chinese crude drug as preparation of raw material, the invention still further relates to the compound method of this medicine.
Background technology
Having the weak point for the treatment of the medicine of burning, scald, burn and wound now is, onset is slow, and zest is strong, and is slow to repair of damaged tissues a little less than the analgesic activity, leaves cicatrix after the healing, maybe needs skin-grafting, amputation etc.Use the patient of existing burn medicine will pass through edema, shock, infect, fester, pyaemia septica, manually make skin graft or the complex treatment programs such as amputation.Occur after the slough liquefaction infecting, festering, pain is serious, and traumatic infection suppurates, and pyaemia septica occurs, in case out of control, can endanger patients ' lives, infect the wound surface obstinate that festers, can only rely at last skin-grafting or amputation.
Summary of the invention
Purpose of the present invention will overcome above-mentioned deficiency exactly, provides that a kind of produce effects is fast, nonirritant, analgesic activity are strong, fast to repair of damaged tissues, medicine and the compound method thereof of leaving no scar after healing, the treatment burn that need not to make skin graft.
For achieving the above object, technical scheme of the present invention is that the medicine of this treatment burn is comprised of the raw material of following weight parts proportioning:
Calculus Bovis 2-4 Moschus 2-4 Squama Manis 10-18 Rhizoma Polygoni Cuspidati 35-45
Rhizoma Coptidis 25-35 Cortex Phellodendri 35-50 Radix Et Rhizoma Rhei 45-55 Rhizoma Dioscoreae Bulbiferae 30-40
Pseudobulbus Bletillae (Rhizoma Bletillae) 45-55 Radix Ampelopsis 35-45 Radix Angelicae Sinensis 42-50 Flos Chrysanthemi 35-45
The Herba Eupatorii Lindleyani 30-40 wooden 35-45 Cacumen Platycladi 35-45 Radix Glycyrrhizae 15-25 that continues
Cornu Bovis seu Bubali 20-30 55% ethanol 25-35 hydroxy benzoate class 3-6 spring water 100
The compound method of the medicine of described treatment burn is:
A, except Calculus Bovis, Moschus, Flos Chrysanthemi, 55% ethanol, hydroxy benzoate class, all the other each components are concocted respectively by the Chinese medicine conventional treatment method;
B, except Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class, all the other each components are pulverized and mixed evenly, add spring water natural fermentation, fermentation temperature rises 5 ℃ by room temperature every day, when rising to 50-60 ℃, keep falling 2 ℃ every day after 48 hours, be down to 10 ℃, kept 28 days, again the room temperature storage;
C, will process through step b the conventional distillation of fermented product of gained, add Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class again in these distillation gains, and stir evenly, the bottling warehouse-in is for subsequent use, as burn spray, liniment.
The amount of described adding spring water also can be as the criterion by spring water covering medicamental pulverata.
During use, clean burn surface with 5% saline, use again warm boiled water flush away saline, put burn surface on the skin with liquid medicine jet of the present invention, cover burn surface with aseptic cotton or gauze, squirt this aseptic cotton or gauze with medicine of the present invention, 24 hours moistening with medicine maintenance of the present invention, open this absorbent cotton or gauze after 24 hours, burn surface was opened wide 2 hours, with the oxidation wound surface, repair granulation promoting, cover again this absorbent cotton or gauze and keep moistening, so reuse, until healing.
In the prescription of the present invention, Calculus Bovis, heat-clearing and toxic substances removing, the anti-corruption of subsiding a swelling; Moschus, promoting blood circulation to remove blood stasis, the analepsia of having one's ideas straightened out; Squama Manis, promoting blood circulation to remove blood stasis, the circulation of qi promoting of stimulating the menstrual flow; Rhizoma Polygoni Cuspidati, blood circulation promoting and blood stasis dispelling, hemostatic bacteriostatic; Rhizoma Coptidis, heat clearing and damp drying, eliminating fire and detoxication, antibacterial blood pressure lowering; Cortex Phellodendri, heat clearing and damp drying, hemostasis blood pressure lowering; Radix Et Rhizoma Rhei, removing mass eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling; Rhizoma Dioscoreae Bulbiferae, hemostasia and detumescence; The Pseudobulbus Bletillae (Rhizoma Bletillae), astringing to arrest bleeding, granulation promoting; Radix Ampelopsis, heat-clearing and toxic substances removing, the detumescence antibacterial; Radix Angelicae Sinensis, promoting blood circulation and stopping pain; Flos Chrysanthemi Indici, heat-clearing and toxic substances removing; Herba Eupatorii Lindleyani, heat-clearing and toxic substances removing, detumescence; The wood that continues, astringing to arrest bleeding; Cacumen Platycladi, cooling blood for hemostasis; Radix Glycyrrhizae, eliminating fire and detoxication, slow pain, the mediation property of medicine; The ethanol sterilization and anticorrosion is regulated the flow of vital energy, is invigorated blood circulation, granulation promoting; Cornu Bovis seu Bubali, clearing away heat,cooling blood and removing toxin.More than all medicine compatibilities, coordinative role is in tissue of burn and whole body.
Compare with existing burn medicine, burn medicine produce effects of the present invention is fast, analgesic activity is strong, action temperature and lasting, nonirritant, the burn slough does not liquefy, fast to repair of damaged tissues, have powerful edema, shock, infection and fester, pyaemia septica does not appear, general healing preventing from scar need not be made skin graft and amputation; Usually after covering absorbent cotton of the present invention or gauze, one, second degree burn 2-3 days healing, dark two degree, third degree burn 3-5 days visible 40% healing can be healed in 10-15 days substantially, can heal fully in 20-35 days.
Hunan Province Huaihua Medical College pharmacy lies in 2002-2003 years, press medicine contrast test rules, do the test of animal burn treating with burn medicine of the present invention, repeat 30 times, result of the test shows, cure rate 98%, skin percent reduction 98%, the present invention and existing burn medicine are relatively, and be fast to repair of damaged tissues, general rear preventing from scar does not need skin-grafting.
The communication hospital, Hunan Province uses the present invention to treat deep ii degree burn patient 16 examples in August, 1997, and cure rate is more than 90%.Clinical treatment shows, uses the present invention, can make burn patient successfully tide over shock, infection and depleted three roads burn difficulty, does not stay ugly cicatrix, dysfunction seldom occurs.The expert thinks, adopts burn medicine of the present invention to infiltrate burn surface, the treatment burn patient, and it is fast to have a pain relieving, can suppress to ooze out, and reduces shock and occurs, and it is rapid to stop blooding, and resistance infection is strong, and extensive deep burn need not the characteristics such as skin-grafting.
The south of a city, Xupu County hospital since nineteen ninety-three, uses the present invention to treat I, II degree and deep burn patient and is respectively 201,327 and 128 examples, treatment burn patient totally 656 examples, wherein, gunpowder 98 people that burn, boiled water is scalded 304 people, petrol burn 5 people, mine gas 5 people that burn, burn 63 people, lime water is scalded 15 people, sulfuric acid burn 3 people, motorcycle exhaust pipe 163 people that burn, cure rate is more than 95%, skin percent reduction 98%.
Over 30 years, the present invention treats the medicine of burn in Xupu County, Hunan Province, Changsha, Liuyang City, and 20 counties and cities such as Guizhou, Guangxi, Yunnan, Guangdong, treat altogether burn patient more than 2000 examples, maximum burn surface area reaches 87%, maximum 65 years old age, minimal ages 10 months, I, the recovery from illness in 2-3 days of II degree burn, dark II, the recovery from illness in 10-35 days of III degree burn, cure rate is more than 90%.
The specific embodiment
Embodiment 1
The medicine of this treatment burn is comprised of the raw material of following weight parts proportioning:
Calculus Bovis 3 Moschus 3 Squama Maniss 15 Rhizoma Polygoni Cuspidati 40 Rhizoma Coptidis 30 Cortex Phellodendris 45
Radix Et Rhizoma Rhei 50 Rhizoma Dioscoreae Bulbiferaes 35 Pseudobulbus Bletillae (Rhizoma Bletillae)s 50 Radix Ampelopsis 40 Radix Angelicae Sinensis 46 Flos Chrysanthemis 40
Herba Eupatorii Lindleyani 35 wooden 40 Cacumen Platycladis, 40 Radix Glycyrrhizaes, 20 Cornu Boviss seu Bubali, 25 55% ethanol 30 that continue
Benzoates 5 spring water 100
The compound method of the medicine of described treatment burn is:
A, except Calculus Bovis, Moschus, Flos Chrysanthemi, 55% ethanol, hydroxy benzoate class, all the other each components are concocted respectively by the Chinese medicine conventional treatment method;
B, except Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class, all the other each components are pulverized and mixed evenly, add spring water natural fermentation, fermentation temperature rises 5 ℃ by room temperature every day, when rising to 50-60 ℃, keep falling 2 ℃ every day after 48 hours, be down to 10 ℃, kept 28 days, again the room temperature storage;
C, will process through step b the conventional distillation of fermented product of gained, add Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class again in these distillation gains, and stir evenly, the bottling warehouse-in is for subsequent use, as burn spray, liniment.
During use, clean burn surface with 5% saline, use again warm boiled water flush away saline, put burn surface on the skin with liquid medicine jet of the present invention, cover burn surface with aseptic cotton or gauze, squirt this aseptic cotton or gauze with medicine of the present invention, 24 hours moistening with medicine maintenance of the present invention, open this absorbent cotton or gauze after 24 hours, burn surface was opened wide 2 hours, with the oxidation wound surface, repair granulation promoting, cover again this absorbent cotton or gauze and keep moistening, so reuse, until healing.
Embodiment 2
Calculus Bovis 2 Moschus 2 Squama Maniss 10 Rhizoma Polygoni Cuspidati 35
Rhizoma Coptidis 25 Cortex Phellodendris 35 Radix Et Rhizoma Rhei 45 Rhizoma Dioscoreae Bulbiferaes 30
The Pseudobulbus Bletillae (Rhizoma Bletillae) 45 Radix Ampelopsis 35 Radix Angelicae Sinensis 42 Flos Chrysanthemis 35
Herba Eupatorii Lindleyani 30 wooden 35 Cacumen Platycladis, 35 Radix Glycyrrhizaes 15 of continuing
Cornu Bovis seu Bubali 20 55% ethanol 25, hydroxy benzoate class 3 spring water 100
The compound method of the medicine of described treatment burn is:
A, except Calculus Bovis, Moschus, Flos Chrysanthemi, 55% ethanol, hydroxy benzoate class, all the other each components are concocted respectively by the Chinese medicine conventional treatment method;
B, except Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class, all the other each components are pulverized and mixed evenly, add spring water natural fermentation, fermentation temperature rises 5 ℃ by room temperature every day, when rising to 50-60 ℃, keep falling 2 ℃ every day after 48 hours, be down to 10 ℃, kept 28 days, again the room temperature storage;
C, will process through step b the conventional distillation of fermented product of gained, add Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class again in these distillation gains, and stir evenly, the bottling warehouse-in is for subsequent use, as burn spray, liniment.
The amount of described adding spring water also can be as the criterion by spring water covering medicamental pulverata.
During use, clean burn surface with 5% saline, use again warm boiled water flush away saline, put burn surface on the skin with liquid medicine jet of the present invention, cover burn surface with aseptic cotton or gauze, squirt this aseptic cotton or gauze with medicine of the present invention, 24 hours moistening with medicine maintenance of the present invention, opens this absorbent cotton or gauze after 24 hours, make burn surface open wide after 2 hours, cover again this absorbent cotton or gauze and keep moistening, so reuse, until healing.
Embodiment 3
Calculus Bovis 4 Moschus 4 Squama Maniss 18 Rhizoma Polygoni Cuspidati 45
Rhizoma Coptidis 35 Cortex Phellodendris 50 Radix Et Rhizoma Rhei 55 Rhizoma Dioscoreae Bulbiferaes 40
The Pseudobulbus Bletillae (Rhizoma Bletillae) 55 Radix Ampelopsis 45 Radix Angelicae Sinensis 50 Flos Chrysanthemis 45
Herba Eupatorii Lindleyani 40 wooden 45 Cacumen Platycladis, 45 Radix Glycyrrhizaes 25 of continuing
Cornu Bovis seu Bubali 30 55% ethanol 35 hydroxy benzoate classes 6 spring water 100
The compound method of the medicine of described treatment burn is:
A, except Calculus Bovis, Moschus, Flos Chrysanthemi, 55% ethanol, hydroxy benzoate class, all the other each components are concocted respectively by the Chinese medicine conventional treatment method;
B, except Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class, all the other each components are pulverized and mixed evenly, add spring water natural fermentation, fermentation temperature rises 5 ℃ by room temperature every day, when rising to 50-60 ℃, keep falling 2 ℃ every day after 48 hours, be down to 10 ℃, kept 28 days, again the room temperature storage;
C, will process through step b the conventional distillation of fermented product of gained, add Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class again in these distillation gains, and stir evenly, the bottling warehouse-in is for subsequent use, as burn spray, liniment.
The amount of described adding spring water can be as the criterion by spring water covering medicamental pulverata.
During use, clean burn surface with 5% saline, use again warm boiled water flush away saline, put burn surface on the skin with liquid medicine jet of the present invention, cover burn surface with aseptic cotton or gauze, squirt this aseptic cotton or gauze with medicine of the present invention, 24 hours moistening with medicine maintenance of the present invention, opens this absorbent cotton or gauze after 24 hours, make burn surface open wide after 2 hours, cover again this absorbent cotton or gauze and keep moistening, so reuse, until healing.

Claims (1)

1. a medicine for the treatment of burn is characterized in that, it is formed by the preparation of raw material of following weight parts proportioning:
Figure FSB00000845543900011
Its compound method is:
A, except Calculus Bovis, Moschus, Flos Chrysanthemi, 55% ethanol, hydroxy benzoate class, spring water, all the other each components are concocted respectively by the Chinese medicine conventional treatment method;
B, except Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class spring water, all the other each components are pulverized and mixed evenly, add spring water natural fermentation, fermentation temperature rises 5 ℃ by room temperature every day, when rising to 50-60 ℃, keeps after 48 hours, fall 2 ℃ every day, be down to 10 ℃, kept 28 days, again the room temperature storage;
C, will process through step b the conventional distillation of fermented product of gained, add Calculus Bovis, Moschus, 55% ethanol, hydroxy benzoate class in these distillation gains, and stir evenly, the bottling warehouse-in is for subsequent use, as burn spray, liniment.
CN200810143727XA 2008-11-20 2008-11-20 Medicament for treating burns and preparation method thereof Expired - Fee Related CN101732567B (en)

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MX2012002437A (en) 2009-08-26 2012-06-27 Mary Kay Inc Topical skin care formulations comprising plant extracts.
CN101890110B (en) * 2010-06-29 2011-08-03 王树强 White tiger sesame oil scalding ointment and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091013A (en) * 1993-02-18 1994-08-24 李国强 Ointment for curing burn and manufacture method thereof
CN1227108A (en) * 1998-04-17 1999-09-01 张宝善 Method for preparing burn plaster
CN1466988A (en) * 2003-06-09 2004-01-14 路玉英 Chinese materia medica preparation for treating burn and scald and method for preparing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091013A (en) * 1993-02-18 1994-08-24 李国强 Ointment for curing burn and manufacture method thereof
CN1227108A (en) * 1998-04-17 1999-09-01 张宝善 Method for preparing burn plaster
CN1466988A (en) * 2003-06-09 2004-01-14 路玉英 Chinese materia medica preparation for treating burn and scald and method for preparing the same

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