CN104138496A - Pills for treating dysuria of the old - Google Patents

Abstract

Pills for treating dysuria of the old are composed of 25% of vegetable cicada, 23% of morinda officinalis how, 10% of common fenugreek seeds, 10% of cinnamomum cassia, 2% of semen pharbitidis, 10% of yam rhizome, 10% of glechoma longituba, 5% of amber, 3% of fennel and 2% of agilawood. The ten kinds of traditional Chinese medicine are smashed ultra-finely, mixed evenly and made into the pills or tablets.

Description

Old difficulty in urination ball

Technical field

the invention belongs to applied technical field, particularly a kind of Chinese patent medicine for the treatment of old man's difficulty in urination.

Background technology

How the old difficulty in urination, caused by prostate hyperplasia, its disease dysuria, and under tiny drop difficulty, even urine obturation is obstructed, little distention and fullness in the abdomen, the white look down of companion's meeting, weak, god dispels, the soreness of waist, knee joint is soft.Control with part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels yang deficiency, capable in order to do the capable water of gas, in order to treat the difficulty in urination due to old prostate hyperplasia.

Summary of the invention

The technical scheme that the treatment old man difficulty in urination adopts is by Cordyceps cicadae Shing, Radix Morindae Officinalis, and Semen Trigonellae, Cortex Cinnamomi is ordered with the kidney invigorating,

Assistant, with Semen Pharbitidis, is removed from office Pi, Glechota longituba (Nakai) Kupr, and succinum, tonneau water channel, with Fructus Foeniculi, Lignum Aquilariae Resinatum regulating functional activities of vital QI, giving consideration to both the incidental and fundamental like this, reinforcing and reducing concurrently, meets differential diagnosis in tcm theory on treatment old man dysuria.Overcome the deficiencies in the prior art, meet the needs of senescence society.

Cordyceps cicadae Shing English name: Vegetable cicada effective ingredient: containing glycogen, cordycepic acid, multiple alkaloid and ergosterol etc.Periostracum cicadae contains a large amount of chitins and nitrogen etc., and its function has the striped muscle of reduction tensity, and neuroganglion is had to blocking effect.It has (1) antitumor action: antitumor action, Periostracum cicadae antitumor, the diffusion of prevention cancerous cell and transfer etc. are by improving the realization of patient's immunity.(2) central nervous system's regulating action: central nervous system acts on that mouse peritoneal is injected natural Periostracum cicadae or the rare alcohol extract of artificial culture product can obviously reduce its autonomic activities, extend the length of one's sleep due to pentobarbital sodium and chloral hydrate, the mice of the improving subliminal hypnosis amount pentobarbital sodium rate of falling asleep.Prove through Writhing test and hot plate method: both analgesic activities are obvious.Give normal and yeast pyrogenicity rats by intraperitoneal injection, there is obvious cooling effect.Separately have data further to prove, Periostracum cicadae and artificial culture thing thereof, have obvious analgesia, calmness and refrigeration function.(3) the main component aminoacid in Periostracum cicadae and multiple Cordyceps is similar in kind, and content is more consistent.Several amino acids is one of material base of strengthening by means of tonics, and pharmacological evaluation proves that the aminoacid of Periostracum cicadae and multiple Cordyceps has benefiting action in various degree.(4) Periostracum cicadae water decoction can obviously extend the swimming time of experiment mice, significantly improves the time-to-live under normobaric hypoxia state and under hot conditions, proves that Periostracum cicadae has resisting fatigue anti-stress effect.(5) functions such as Cordyceps cicadae Shing has the blood of reduction, urine creatine, improves endogenous creatinine clearance rate, improves serum albumin content, the discharge of minimizing urine protein.Therefore, to early, mid-term chronic renal insufficiency patient determined curative effect.Confirm after further study: Periostracum cicadae has good therapeutic effect to kidney interstitial tubule pathological changes; can protect renal tubular cell Na+-K+-ATP enzyme; alleviate Cytolysosome and cytolipin peroxide injury, improve renal hemodynamics, alleviate endothelial cell damage and blood coagulation.Therefore think that Periostracum cicadae can improve renal function.In a word: the multiple actions such as Cordyceps cicadae Shing has immunity, resisting fatigue, guarantor's kidney, improvement, sleep, the antitumor of raising, protects the liver, radioprotective and improving eyesight are magical ancient Chinese medicine.The Periostracum cicadae of artificial culture is containing mannitol, polysaccharide, and aminoacid, cordycepin adenosine, this is similar to natural cordyceps, but the toxic heavy metals such as arsenic, hydrargyrum, lead do not detect, and this is than natural cordyceps safety.Therefore, Cordyceps cicadae Shing can be used as the succedaneum of Cordyceps, can reach equally the effect of nourishing and health preserving.

Radix Morindae Officinalis (formal name used at school: morinda officinalis How) root is containing anthraquinone component: Rubiadin (rubiadin), Rubiadin 1-methylether (rubiadin-1-methyl ether), physcione (physcion), 2-hydroxyl methylol anthraquinone (2-hydroxy-3-hydrox-ymethylanthraquinone), 1-hydroxyanthraquinone (1-hydroxyanthraquinone), 1-hydroxy-2-methyl anthraquinone (1-hydroxy-2-methyl anthraquinone), 1, 6-dihydroxy-2, 4-dimethoxy anthraquinone (1, 6-dihydroxy-2, 4-dimethoxyan-thraquinone), 1, 6-dihydroxy-2-methoxyl group anthraquinone (1, 6-dihydroxy-2-methoxyanthraquinone), 2-methylanthraquinone (2-methylanthraqui-none), also containing iridoid composition, Monotropein (Monotropein), tetrem acyl rubichloric acid. (asperuloside teTCMLIBaacetate).Contain again glucose (glucose), mannose (mannose), cupreol (β-sitosterol), Palmic acid (palmitic acid).Vitamin (vitamin) C, nonadecane (nonadecane), 24-ethyl cholesterol (24-ethyl cholesterol).Root bark is containing 23 kinds of elements such as zinc, manganese, ferrum, chromium.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Research shows, often low with immunologic function of deficiency syndrome patient, and the non-specific and (or) specific immune function that qi-restoratives medicine can enhancing body, this is one of pharmacological basis of its strengthening vital QI to eliminate pathogenic factors effect.The important indicator of selecting 2 reflection body's immunities of splenocyte breeder reaction and antibody formation reaction to change, study the impact of Radix Morindae Officinalis oligosaccharide (MOO) on immunologic function, the oral MOO of giving has obvious facilitation to normal mouse boosting cell breeder reaction, and can obviously strengthen splenocyte antibody formation number, show that MOO has obvious facilitation to the immunologic function of normal mouse.To splenocyte, breeder reaction has no significant effect external application MOO.Research both domestic and external shows, Inulin-type oligosaccharide is non-digestion type oligosaccharide, substantially not digested absorption in gastrointestinal tract.Therefore, we have studied the effect of MOO to intestinal Peyer ' s Patchs cell (intestinal lymphocyte), and result shows that breeder reaction has no significant effect MOO to PP nodal cell equally.The above results prompting, the facilitation of MOO to immunologic function, may not produce by directly acting on immunologically competent cell.Research finds that bar halberd polysaccharide can increase mouse thymus weight childhood, obviously improves mouse macrophage phagocytic percentage, and can obviously improve the special rosette forming cell of mice RFC(immunity) formation.The immunological enhancement of Radix Morindae Officinalis, may stimulate the cytokine producing closely related with Radix Morindae Officinalis.Found through experiments the secretion that Radix Morindae Officinalis can promote mouse boosting cell IL--2, make the level of IL--2 be significantly higher than Normal group (P<0.01).Because IL--2 has obvious stimulation to T cell, B cell and NK cell, and can bring out LAK cell, interferon etc.Therefore, IL--2 plays the regulating action at center in immunne response network.And Radix Morindae Officinalis can regulate the activity of IL--2, it may be one of important mechanisms of its immunostimulant, immunoregulation effect.

Semen Trigonellae [English name] Common fenugreek seed warming the kidney to activate YANG,

Seed is containing alkaloids such as erythricine, carpaine, choline, trigonellines, and ruscogenin is mainly diosgenin, Yamogenin and a small amount of gitogenin, trace Tigogenin.Still isolate the Arabic glucoside of vitexin, vitexin-7-glycoside, orientin or isorientin, glucose rhamnose two glucosides of flavone, the flavonoids such as Quercetin, luteolin.Generally consisting of of seed: moisture 10.30%, ash 3.15%, lipase 37 .61%, total protein 16.97%, total sugar 3.68%, cellulose 6.4%, hemicellulose 11.98%.Solid fatty acid 92.9%, volatile fatty acid 1.5%, not saponification composition 0.9% in fatty oil; Lecithin 6.25%, plant sterol 0.5 reveal.In fatty acid, be mainly linoleic acid and Palmic acid, and have a small amount of oleic acid and linolenic acid.Nucleoprotein 55% in protein.In total sugar, be mainly galactomannan, also containing vitamin B1-320 microgram %.Leaf is containing approximately 43 milligrams of % of ascorbic acid.Herb is also rich in calcium, ferrum, carotene etc." book on Chinese herbal medicine justice ": Semen Trigonellae is the replenishing vital QI with drugs of warm nature part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the medicine of catharsis cold, descendant, to control the cards such as hernia abdominal mass, beriberi, must be that kidney-Yang declines, water cold stagnant person be advisable.

Cortex Cinnamomi, canella, formal name used at school is Cinnamomum cassia.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Cortex Cinnamomi acrid in the mouth, sweet, hot in nature; Return kidney, the heart, spleen, Liver Channel; Fragrant peppery gas is thick, falls and the liter of holding concurrently, and can walk and can keep.

Glechota longituba (Nakai) Kupr has another name called BIANDIXIANG, Herba Lysimachiae etc. and enters liver, gallbladder, kidney, bladder, lung meridian, diuresis clearing heat and freeing strangury, clearing away heat-damp and promoting diuresis aroma type are containing volume monoterpene ketone, and composition is k-pinocamphone (k mono-Pinocamphone), k-menthone (k-Menthone) and k-pulegone (k-Pulegone); Still containing a-pinene (a-Pinene), B-pinene, limonene (Limonene), to a P-cymene (p-Cymene), isomenthone (Isomenthone), isopinocamphone (Isopinocamphone), linalool (Linalool), menthol (Menthol), a-terpineol (a-erpineol).Except above-mentioned volatile oil component, still containing ursolic acid (Ursolic acid), B-sitosterol, Palmic acid, succinic acid, several amino acids, tannin, amaroid, choline, potassium nitrate etc.Under ground portion is containing stachyose (Stachyose).

Semen Pharbitidis ^[1](English name: SEMEN PHARBITIDIS.), another name: Semen Pharbitidis, Semen Pharbitidis, Semen Pharbitidis, trumpet flower, lead a cow, spend towards face.Removing water retention by purgation relieving constipation, drink is washed in expectorant, and parasite killing is attacked long-pending.For edema distension, constipation and anuresis, phlegm retention is gathered, and QI rising in reverse order is breathed with cough.

The turbid expelling wind and removing dampness of leather Pi's dampness removingization.

The English name of succinum is Amber, and from Latin Ambrum, the meaning is " marrow ".Chemical molecular formula C ₁₀h ₁₆o, containing a small amount of hydrogen sulfide, trace element kind has aluminum, magnesium, calcium, silicon etc. in addition.Up-to-date scientific research proves, succinic acid has active influence to human organ.It can enhancing immunity, make the balance of the energetic and holder inner acidic of people.Modern bacteriological advocate carried out careful analysis to succinic acid: the Nobel laureate in 1886, the conspicuous positive influences of having affirmed succinic acid of bacteriologist Robert section of Germany, the accumulation of the residue that he finds succinic acid in human body can not bring any negative effect, or even take into excessive succinic acid be also harmless.Succinum is famous and precious Chinese crude drug.In " Mingyi Bielu ", succinum is listed in top grade, has the function of the arresting convulsion of calming the nerves, scattered silt blood, diuresis.Record according to bright Li Shizhen (1518-1593 A.D.) Compendium of Material Medica: succinum abnormal smells from the patient sweet flat, nontoxic, can settling five organs, determine soul, the congestion that disappears, lead in five types of stranguria, high aspiration improving eyesight, pain relieving is calmed the nerves, removing blood stasis life, treats malaise, insomnia and dreamful sleep.

Fructus Foeniculi [formal name used at school]: Foeniculum vulgare English name: Fennel, acrid in the mouth, warm in nature.Stimulating appetite, the cold expelling of regulating the flow of vital energy, has supporing yang road.Cure mainly: cold in middle-JIAO, loss of appetite, nausea and vomiting, abdominal part cold type of pain; Hernia pain, painful and swollen testis; Stagnation of QI in spleen and stomach, distension and fullness in the abdomen is had a pain.

Lignum Aquilariae Resinatum health preserving promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.Lignum Aquilariae Resinatum, as a kind of medicine, has good regulatory function for the every function of human body.The traditional Chinese medical science is especially particular about people's " gas ", and normal circulation of qi and blood, can not invade by hundred poison, and this is also the glamour place than doctor trained in Western medicine traditional Chinese medical science extensive knowledge and profound scholarship.And Lignum Aquilariae Resinatum is exactly the operation by adjusting gas in balance human body, reach the effect for the treatment of or health care.

This Ten Herbs is pacified to following mass percent preparation, and superfine grinding, evenly mixes and stirs, and makes pill or tablet: Cordyceps cicadae Shing 25% Radix Morindae Officinalis 23% Semen Trigonellae 10% Cortex Cinnamomi 10% Semen Pharbitidis 2% is removed from office Pi 10% Glechota longituba (Nakai) Kupr 10% succinum 5% Fructus Foeniculi 3% Lignum Aquilariae Resinatum 2%.

Detailed description of the invention:

Oral three times of difficulty in urination ball (sheet) every day, each 6-8 gram, after meal warm water delivery service.It within seven days, is a course for the treatment of.Test altogether 50 many cases, effective percentage is more than 85%.Anemia of pregnant woman, child avoids use, liver, renal function poor person be cautious use of.The patient Qin so-and-so, man, 74 years old, retired professor, urine difficulty for many years, western medicine poor effect, takes difficulty in urination ball, oral three times of every day, each 6-8 gram, warm water delivery service after meal, first quarter moon takes effect, recovery from illness in January, urine normal so far.Patient's money so-and-so, man, 85 years old.Retirement engineer, urine difficulty, takes difficulty in urination ball, oral three times of every day, each 6-8 gram, warm water delivery service after meal, first quarter moon takes effect, and advises and is careful in one's diet, drink water more, appropriate exercise, urine normal so far, health condition is good.

Claims (1)

1. treat the Chinese patent medicine of the old difficulty in urination for one kind, the Chinese crude drug and the proportioning that it is characterized in that it are as follows: Cordyceps cicadae Shing 25% Radix Morindae Officinalis 23% Semen Trigonellae 10% Cortex Cinnamomi 10% Semen Pharbitidis 2% is removed from office Pi 10% Glechota longituba (Nakai) Kupr 10% succinum 5% Fructus Foeniculi 3% Lignum Aquilariae Resinatum 2%, this Ten Herbs superfine grinding, evenly mix and stir, make pill or tablet.