CN108310159A - A kind of plaster of blood pressure lowering and preparation method thereof - Google Patents
A kind of plaster of blood pressure lowering and preparation method thereof Download PDFInfo
- Publication number
- CN108310159A CN108310159A CN201810373484.2A CN201810373484A CN108310159A CN 108310159 A CN108310159 A CN 108310159A CN 201810373484 A CN201810373484 A CN 201810373484A CN 108310159 A CN108310159 A CN 108310159A
- Authority
- CN
- China
- Prior art keywords
- parts
- plaster
- blood pressure
- grams
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
Abstract
The invention discloses a kind of plaster of blood pressure lowering, the plaster is made of the raw material of following parts by weight：15 30 parts of wild jujube root, 10 20 parts of Prunella vulgaris, 10 30 parts of pueraria lobata, 10 30 parts of cassia seed, 6 15 parts of ginkgo leaf, 5 15 parts of decumbent corydalis tuber, 10 30 parts of palma, 10 25 parts of Herba Epimedii, 5 15 parts of keel, 5 15 parts of valerian, 15 30 parts of hawthorn, 5 20 parts of the root of bidentate achyranthes, 5 10 parts of uncaria, 5 20 parts of chrysanthemum, 5 20 parts of magnetite, 10 20 parts of Polygonum multiflower knotweed, 5 15 parts of the seed of feather cockscomb.The present invention is by all dialectical compatibilities of taste Chinese medicine, and mutually auxiliary help, obtained plaster ingredient is warm-natured, can temperature can dissipate, have the benefits of eliminating cold to stop pain, dispersing stagnated hepatoqi, strongly fragrant eliminating dampness solution.By the Transdermal absorption of the back side of head, antihypertensive effect is apparent, and effectively mitigates nerve reaction caused by the hypertension such as headache, dizzy, insomnia, dizzy, securely and reliably, has no adverse reaction, is worth clinical application.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of plaster of blood pressure lowering and preparation method thereof.
Background technology
High blood pressure, abbreviation hypertension are the general metabolism disease with blood pressure raising for primary feature and life side
Formula is diseases related, is the most important risk factor of cardiovascular and cerebrovascular diseases.The symptom of hypertension varies with each individual, and early stage may be asymptomatic
Or symptom unobvious, only blood pressure can occur after tired, nervous, mood swing and increase, and be returned to normal after a break.
Blood pressure significantly persistently increases with the prolongation of the disease course, gradually will appear various symptoms, is referred to as benign hypertension at this time,
The common clinical symptoms of benign hypertension have headache, dizziness, absent minded, failure of memory, extremity numbness, enuresis nocturna
Increase, is palpitaition, uncomfortable in chest, weak etc..When blood pressure is suddenly increased to a certain degree even will appear severe headache, vomiting, palpitaition,
Clouded in mind, twitch can occur when serious for the symptoms such as dizziness, this just belongs to accelerated hypertension and hypertension critical illness, more meetings
Damage and the lesion of the organs such as the serious heart, brain, kidney, such as apoplexy, heart infarction, renal failure occur in a short time.
Currently, the drug for the treatment of hypertension is more, common hypotensor mainly with reserpine, verticilum, captopril,
Based on happy happiness equality Western medicine, although Western medicine energy respite and control hypertension, its side effect is very big, to the heart, liver, kidney etc.
There is stimulation, and palliative, can only play the role of controlling blood pressure, once being discontinued, blood pressure can rebound quickly.
Chinese pharmacology thinks that high blood pressure belongs to the card scope such as Chinese medicine " dizziness ", " headache ", " liver-yang ", " apoplexy ", with liver, kidney
Two is dirty related, and constitution yin or yang excess or partially empty, qi and blood functional disturbance is the internal factor of morbidity.The interpretation of the cause, onset and process of an illness is crucial and due to feelings will
Unsuccessful, intemperance of taking food, internal injury are deficient cause yang blood and qi dysequilibrium caused by, lesion portion is mainly in liver kidney, and and heart spleen.
The principle of dialectical treatmert is emphasized in Chinese traditional treatment, with treating both manifestation and root cause of disease, the apparent advantages such as drug side-effect is low.It is existing
Although Chinese medicine for lowering blood pressure can improve the blood pressure of hypertensive patient to a certain extent, but still exist and work slow and be difficult to maintain
The defect that prolonged blood pressure balances, treatment cycle is long and cannot thoroughly cure.
Invention content
Present inventor on the basis of theory of traditional Chinese medical science, in conjunction with to hypertension incidence mechanism understanding and research, lead to
It crosses a large amount of experiment and obtains the blood pressure lowering plaster of the present invention, the plaster raw material proportioning is scientific and reasonable, and mutual coordinated increases
By force, it is excellent to have that significant in efficacy, healing time is short, patient compliance is good, safe, easy to use etc. for plaster provided by the invention
Point.
Of the existing technology in order to solve the problems, such as, the purpose of the present invention is to provide a kind of plaster of blood pressure lowering, this hairs
It is bright to additionally provide a kind of preparation method of the plaster of blood pressure lowering.
To achieve the above object, the first aspect of the present invention provides a kind of plaster of blood pressure lowering, and the plaster is by following
The raw material of parts by weight forms：
15-30 parts of wild jujube root, 10-20 parts of Prunella vulgaris, 10-30 parts of pueraria lobata, 10-30 parts of cassia seed, 6-15 parts of ginkgo leaf, summer
It without 5-15 parts, 10-30 parts of palma, 10-25 parts of Herba Epimedii, 5-15 parts of keel, 5-15 parts of valerian, 15-30 parts of hawthorn, the root of bidentate achyranthes
5-20 parts, 5-10 parts of uncaria, 5-20 parts of chrysanthemum, 5-20 parts of magnetite, 10-20 parts of Polygonum multiflower knotweed, 5-15 parts of the seed of feather cockscomb.
Further, the plaster is made of the raw material of following parts by weight：
20-30 parts of wild jujube root, 10-20 parts of Prunella vulgaris, 10-20 parts of pueraria lobata, 20-30 parts of cassia seed, 8-12 parts of ginkgo leaf, summer
It without 10-15 parts, 15-25 parts of palma, 20-25 parts of Herba Epimedii, 5-15 parts of keel, 5-10 parts of valerian, 20-30 parts of hawthorn, ox
12-18 parts of knee, 5-10 parts of uncaria, 10-20 parts of chrysanthemum, 5-10 parts of magnetite, 15-20 parts of Polygonum multiflower knotweed, 10-15 parts of the seed of feather cockscomb.
Further, the plaster is made of the raw material of following parts by weight：
25 parts of wild jujube root, 20 parts of Prunella vulgaris, 20 parts of pueraria lobata, 25 parts of cassia seed, 10 parts of ginkgo leaf, 12 parts of decumbent corydalis tuber, palm
20 parts of leaf, 20 parts of Herba Epimedii, 10 parts of keel, 8 parts of valerian, 25 parts of hawthorn, 15 parts of the root of bidentate achyranthes, 10 parts of uncaria, 15 parts of chrysanthemum, magnetite 10
Part, 15 parts of Polygonum multiflower knotweed, 10 parts of the seed of feather cockscomb.
The second aspect of the present invention provides the preparation method of the plaster of above-mentioned blood pressure lowering, the preparation method include with
Lower step：
1) feedstock processing：The raw material of corresponding parts by weight is weighed, is crushed spare；
2) spice extracts：It takes sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 210-230 DEG C, and constantly
Stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 310-330 DEG C, until medicine oil dropping into a bead, refining
Oil is completed；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 280-300 DEG C, yellow lead is added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 5-7 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 40-60 DEG C, is then evenly coated in medicated plaster cloth
It is upper.
Further, the raw material in step 1) is ground into fine powder, crosses 200-300 mesh sieve.
Further, it counts in parts by weight, sesame oil is 1000-1200 parts.
Further, it counts in parts by weight, yellow lead is 500-600 parts.
The third aspect of the present invention provides application of the above-mentioned plaster in the drug for preparing treatment hypertension.
The effect of each taste Chinese medicine selected by the present invention, is as follows：
Wild jujube root：Puckery, it is warm-natured.With sedative action, analgesic, diuresis effect are had concurrently.It cures mainly：Insomnia, neurasthenia.It grinds
Study carefully and shows that wild jujube root contains following chemical composition：Lupeol, betulinic acid, ceanothic acid, different ceanothic acid, stigmasterol, beans
Sterol -3-O- glucosides, adovetin.
Prunella vulgaris：Acrid flavour, hardship, it is cold in nature.Return liver, gallbladder channel.Have effects that clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating.Modern medicine
Reason is studies have shown that Prunella vulgaris contains the glycosides substances such as triterpenoid saponin, rutin sophorin, Hyperoside and ursolic acid, caffeic acid, dissociates together earnestly
The organic acids such as tartaric acid；Containing delphinidin, the anthocyanin of Cyanidin, d- camphors, d- fenchones etc. in flower spike, have decompression,
Anti-inflammatory and antibacterial action.
Pueraria lobata：It is sweet in flavor, pungent, it is cool in nature.It attaches to the lung and stomach meridians.It brings down a fever with expelling pathogenic factors from muscles and skin, promoting eruption promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie
Effect.Modern research shows that the total Pueraria lobota ketone of pueraria lobata and Puerarin can be such that plasma renin activity and angiotensins significantly reduces, under blood pressure
Drop.Puerarin improves significantly to microcirculation disorder, is mainly shown as the amplitude for increasing Microvascular angina and raising office
The micro- blood flow in portion；Pueraria Flavonid has the function of apparent expansion of cerebral vascular, improves brain microcirculation and peripheral circulation.It is reported that
Puerarin can also improve the arrested state of retinal vessel end slightly unit, to improve visual function.
Cassia seed：Bitter, sweet, salty, cold nature enters liver, kidney, large intestine channel.Have the function of clearing liver and improving vision, moisten it is unimpeded just.
Modern pharmacological studies have shown that cassia seed contains Anthraquinones, naphtho--pyrrolones, fatty acid, amino acid and inorganic elements, tool
There are reducing blood lipid, blood pressure lowering isoreactivity, it is especially preferable to the angiocardiopathies curative effect such as hypertension, hyperlipidemia.
Ginkgo leaf：It is sweet in flavor, bitter, puckery, it is mild-natured.Distributed in heart and lung channels.It with promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringes the lung and relieving asthma, change turbid
The effect of lipid-loweringing.Modern research shows that ginkgo leaf reduces blood pressure by increasing vascular permeability and elasticity, there is preferable decompression work(
Effect.
Decumbent corydalis tuber：Bitter, micro-pungent, it is warm-natured.Return liver warp.Modern research shows that decumbent corydalis tuber stem tuber containing tetrahydropalmatine, former Ah
A variety of alkaloids such as piece alkali, bulbocapnine, adlumidine alkali.With decompression antispastic, promoting qi circulation and relieving pain, the work(of blood circulation and promoting silt
Effect.Cure mainly hypertension, hemiplegia, rheumatic arthritis, sciatica, sequelae of infantile paralysis.
Palma：It is bitter, puckery, it is mild-natured.Returns spleen, stomach.With astringing to arrest bleeding, the effect of blood pressure lowering.
Herba Epimedii：Containing ingredients such as icariine, volatile oil, ceryl alcohol, phytosterol, tannin, vitamin Es.Pharmacological evaluation is ground
Study carefully and show that Herba Epimedii can inhibit blood pressure caused by blocking rabbit bilateral common carotid arteries and increase, illustrates that icariin passes through to coronary blood
Pipe, femoral artery blood vessel and cerebrovascular dilating effect, and reach decompression purpose, in addition, Herba Epimedii can increase cardiovascular and cerebrovascular blood flow
Amount promotes hematopoiesis function, immune function and bone metabolism, has anti-aging, antitumor and other effects.
Keel：Nature and flavor are sweet, puckery, put down.Enter the heart, liver, kidney, large intestine channel.Major function is calm, puckery essence of arrest sweating, myogenic sore.With
In neurasthenia, palpitaition, insomnia, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, uterine bleeding, under；Sore burst for a long time and does not holds back is controlled in external application.
Valerian：Acrid flavour；It is bitter；It is warm-natured.The thoughts of returning home；Liver Channel.Have effects that tranquilizing mind, wind-damp dispelling, qi and blood circulation promotion, analgesic.Contain
The alkaloids such as valerianine, valerianine, valerianae alkaloid A, satin grass alkaloid B, actinidine, valerianine.Modern pharmacology is ground
Study carefully and shows that valerian has resisting pathogenic microbes effect, anticancer, function of tumor inhibition, has sedation, blood pressure lowering to nervous system
Effect, this effect acts on its quasi- parasympathetic sample, blocks quiet artery sinus reflex and central nervous system related.
Hawthorn：Sour, sweet, tepor.Returns spleen, stomach, Liver Channel.With food digesting stomach fortifying, the effect of scattered stasis.Some researches show that,
Hawthorn energy prevention and cure of cardiovascular disease reduces serum cholesterol and triglycerides, effectively prevents atherosclerosis；Hawthorn can also lead to
Cross enhancing myocardial contractive power, increase cardiac output etc., play the role of cardiac stimulant and prevents anginal.In addition, total Huang in hawthorn
Ketone plays the role of expanding blood vessel and lasting buck.
The root of bidentate achyranthes：Bitter, acid, puts down.Return liver and kidney channel.With filling liver kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow, the effect of ensurining proper downward flow of the blood.With
In soreness of waist and knee joint, muscles and bones is powerless, Amenorrhea abdominal mass, dizziness due to hyperactivity of liver-YANG.Modern research shows that containing following chemical components in the root of bidentate achyranthes：Three
Terpene saponins, a variety of polysaccharides, ecdysterone, Inokosterone, rubrosterone etc..It is viscous with cardiac stimulant, blood pressure lowering, reduction blood
The effects that degree, anti-inflammatory and analgesic activity, anti-aging.
Uncaria：It is sweet, it is cool.Return liver, pericardium channel.With The flat liver of heat-clearing, the effect of dispelling wind and relieving convulsion.Modern pharmacological studies have shown that
The alkaloids such as the rhynchophyllin, isorhynchophylline, the corynoxeine that contain in uncaria have antihypertensive effect.
Chrysanthemum：It is sweet, bitter, it is slightly cold.Return lung, Liver Channel.Major function relieve heat heat-clearing, flat liver improving eyesight.Research shows that containing gland is contained
Purine, choline, stachydrine, butterflybush flower glycosides, camphor, borneol, cyanidenon, cyanidenon -7-0- rhamnoglucosides, carypohyllene
The ingredients such as oxide.Modern pharmacological studies have shown that chrysanthemum has antibacterial, expansion coronary artery, increases coronary flow, improves myocardial oxygen consumption
The effects that amount.
Magnetite：With calming the liver, hearing-improing and eyesight improving, the effect of tranquillizing the mind by relieving convulsion, gas of receiving is relievingd asthma.
Polygonum multiflower knotweed：Sweet in flavor, slight bitter, it is mild-natured.Converge to heart and liver channels.With mental-tranquilization, the effect of dispelling wind and removing obstruction in the meridians.Cure mainly insomnia
Dreaminess, deficiency of blood bodily pain, numbness, arthralgia pain due to rheumatism, wind sore scabies tinea.
The seed of feather cockscomb：Bitter is slightly cold.Return liver warp.With clearing liver, improving eyesight, the effect of moving back screen.For the hot hot eyes of liver, screen of looking unfamiliar
Film, blurring of vision, hepatopyretic vertigo.Modern pharmacology research show the seed of feather cockscomb have diffusion pupil, reduce intraocular pressure, reduce blood pressure,
The effects that antibacterial.
Motherland's medicine thinks that hypertension category Chinese medicine " dizziness " " headache " scope, it is the stagnation of the circulation of vital energy, blood stasis, phlegm that pathogenesis, which is worked as,
The operation that essential resistance of turbid influences train of thought is unobstructed, so that body imbalance of yin and yang, channels and collaterals, internal organs, qi and blood dysfunction.
The application method of plaster of the present invention：The plaster made is placed on the inside of pillow, upward, patient's powder lies low in pillow
On, it is contacted with powder by the back side of head of patient, so that drug is absorbed through skin, pore and the acupuncture point at the back side of head, directly
Up to lesion, inner disease outer treat, to achieve the purpose that decompression.The daily time that lies low is 10-15 hours, replaces plaster every three days.
The invention has the advantages that：
1, the present invention is by all dialectical compatibilities of taste Chinese medicine, and mutually auxiliary help, obtained blood pressure lowering plaster ingredient is warm-natured, can temperature
It can dissipate, there is the benefits of eliminating cold to stop pain, dispersing stagnated hepatoqi, strongly fragrant eliminating dampness solution.Because of back side of head rich blood vessel, blood circulation is good, Medicated Permeation
Property it is strong, by the Transdermal absorption of the back side of head, hypertensive patient's blood pressure can be reduced, and decompression does not rebound, therapeutic effect significantly and has
Nerve is reacted caused by effect mitigates the hypertension such as headache, dizzy, insomnia, dizzy.
2, it is raw material that the present invention, which selects common Chinese medicinal herbs, and cost is relatively low, and preparation method is simple and easy to operate, obtained cream
Medicine is apparent to treatment antihypertensive effect, securely and reliably, has no adverse reaction, is worth clinical application.
Specific implementation mode
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
A kind of plaster of blood pressure lowering, is made of the raw material of following weight：
18 grams of wild jujube root, 10 grams of Prunella vulgaris, 10 grams of pueraria lobata, 30 grams of cassia seed, 12 grams of ginkgo leaf, 10 grams of decumbent corydalis tuber, palm
10 grams of leaf, 25 grams of Herba Epimedii, 12 grams of keel, 10 grams of valerian, 30 grams of hawthorn, 5 grams of the root of bidentate achyranthes, 8 grams of uncaria, 15 grams of chrysanthemum, magnetite 20
Gram, 15 grams of Polygonum multiflower knotweed, 5 grams of the seed of feather cockscomb.
The preparation method of the plaster of the blood pressure lowering of the present embodiment, includes the following steps：
1) feedstock processing：The raw material for weighing corresponding weight is ground into fine powder, and it is spare to cross 200 mesh sieve；
2) spice extracts：It takes 1000 grams of sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 210 DEG C, not
Disconnected stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 330 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 280 DEG C, 500 grams of yellow lead are added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 5 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 55 DEG C, is then evenly coated in medicated plaster cloth
.
Embodiment 2
A kind of plaster of blood pressure lowering, is made of the raw material of following weight：
15 grams of wild jujube root, 20 grams of Prunella vulgaris, 20 grams of pueraria lobata, 20 grams of cassia seed, 6 grams of ginkgo leaf, 5 grams of decumbent corydalis tuber, palma
25 grams, 20 grams of Herba Epimedii, 10 grams of keel, 15 grams of valerian, 20 grams of hawthorn, 12 grams of the root of bidentate achyranthes, 8 grams of uncaria, 10 grams of chrysanthemum, magnetite 10
Gram, 20 grams of Polygonum multiflower knotweed, 12 grams of the seed of feather cockscomb.
The preparation method of the plaster of the blood pressure lowering of the present embodiment, includes the following steps：
1) feedstock processing：The raw material for weighing corresponding weight is ground into fine powder, and it is spare to cross 250 mesh sieve；
2) spice extracts：It takes 1000 grams of sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 220 DEG C, not
Disconnected stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 320 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 300 DEG C, 600 grams of yellow lead are added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 7 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 40 DEG C, is then evenly coated in medicated plaster cloth
.
Embodiment 3
A kind of plaster of blood pressure lowering, is made of the raw material of following weight：
20 grams of wild jujube root, 15 grams of Prunella vulgaris, 30 grams of pueraria lobata, 26 grams of cassia seed, 15 grams of ginkgo leaf, 12 grams of decumbent corydalis tuber, palm
15 grams of leaf, 10 grams of Herba Epimedii, 5 grams of keel, 5 grams of valerian, 25 grams of hawthorn, 20 grams of the root of bidentate achyranthes, 10 grams of uncaria, 5 grams of chrysanthemum, 5 grams of magnetite,
15 grams of Polygonum multiflower knotweed, 15 grams of the seed of feather cockscomb.
The preparation method of the plaster of the blood pressure lowering of the present embodiment, includes the following steps：
1) feedstock processing：The raw material for weighing corresponding weight is ground into fine powder, and it is spare to cross 250 mesh sieve；
2) spice extracts：It takes 1100 grams of sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 230 DEG C, not
Disconnected stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 310 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 290 DEG C, 550 grams of yellow lead are added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 6 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 60 DEG C, is then evenly coated in medicated plaster cloth
.
Embodiment 4
A kind of plaster of blood pressure lowering, is made of the raw material of following weight：
25 grams of wild jujube root, 20 grams of Prunella vulgaris, 20 grams of pueraria lobata, 25 grams of cassia seed, 10 grams of ginkgo leaf, 12 grams of decumbent corydalis tuber, palm
20 grams of leaf, 20 grams of Herba Epimedii, 10 grams of keel, 8 grams of valerian, 25 grams of hawthorn, 15 grams of the root of bidentate achyranthes, 10 grams of uncaria, 15 grams of chrysanthemum, magnetite 10
Gram, 15 grams of Polygonum multiflower knotweed, 10 grams of the seed of feather cockscomb.
The preparation method of the plaster of the blood pressure lowering of the present embodiment, includes the following steps：
1) feedstock processing：The raw material for weighing corresponding weight is ground into fine powder, and it is spare to cross 200 mesh sieve；
2) spice extracts：It takes 1200 grams of sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 230 DEG C, not
Disconnected stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 320 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 280 DEG C, 520 grams of yellow lead are added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 5 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 60 DEG C, is then evenly coated in medicated plaster cloth
.
Embodiment 5
A kind of plaster of blood pressure lowering, is made of the raw material of following weight：
30 grams of wild jujube root, 15 grams of Prunella vulgaris, 15 grams of pueraria lobata, 10 grams of cassia seed, 8 grams of ginkgo leaf, 15 grams of decumbent corydalis tuber, palma
30 grams, 15 grams of Herba Epimedii, 15 grams of keel, 8 grams of valerian, 20 grams of hawthorn, 18 grams of the root of bidentate achyranthes, 5 grams of uncaria, 20 grams of chrysanthemum, 8 grams of magnetite,
15 grams of Polygonum multiflower knotweed, 10 grams of the seed of feather cockscomb.
The preparation method of the plaster of the blood pressure lowering of the present embodiment, includes the following steps：
1) feedstock processing：The raw material for weighing corresponding weight is ground into fine powder, and it is spare to cross 250 mesh sieve；
2) spice extracts：It takes 1000 grams of sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 230 DEG C, not
Disconnected stirring, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 310 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 300 DEG C, 580 grams of yellow lead are added portionwise
It in medicine oil, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 7 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 45 DEG C, is then evenly coated in medicated plaster cloth
.
Test example
There is the therapeutic effect of blood pressure lowering, the present invention to have carried out following clinical trial in order to illustrate the plaster of the present invention.
1, patient data
It chooses the primary hypertension patient 300 accepted for medical treatment during in June, -2016 in June, 2010 and is used as research object, examine
Disconnected and grade scale according to《WHO/ISH Treatment Guidelines for Hypertension》.Wherein, I grades of hypertension 95, II grades of 120 Cases of Hypertension,
III level hypertension 85.260 patients show dizziness, have a sleepless night, headache, dreaminess, red tongue body, yellow tongue fur, the clinical conditions such as veins string
Shape.
Using the principle of random, balanced control, 300 cases are randomly divided into each 50 of 1-5 groups for the treatment of, control group 50
Example, carries out the observation of curative effect between group before and after treatment, and the course for the treatment of is 2 months.
Analysis of comparable between two groups：Two groups of cases compare in terms of gender, age, the course of disease：
1 group 50 are treated, wherein man 28, female 22, maximum 68 years old 23 years old minimum, average age 36.7 ± 8.2 years old, disease
Journey is most 1 year short, longest 12 years；
2 groups 50 are treated, wherein man 30, female 20, maximum 70 years old 22 years old minimum, average age 35.8 ± 9.7 years old, disease
Journey is most 1.5 years short, longest 12 years；
3 groups 50 are treated, wherein man 26, female 24, maximum 70 years old 22 years old minimum, average age 37.2 ± 7.8 years old, disease
Journey is most 1 year short, longest 14 years；
4 groups 50 are treated, wherein man 25, female 25, maximum 69 years old 20 years old minimum, average age 36.1 ± 8.1 years old, disease
Journey is most 2 years short, longest 10 years；
5 groups 50 are treated, wherein man 31, female 19, maximum 68 years old 21 years old minimum, average age 38.2 ± 7.0 years old, disease
Journey is most 1.5 years short, longest 12 years；
Control group 50, wherein man 32, female 18, maximum 72 years old 22 years old minimum, average age 36.5 ± 8.5 years old, disease
Journey is most 1.5 years short, longest 11 years.
Through statistical analysis, treats preceding two groups of cases and compare in terms of gender, age, the course of disease and the state of an illness, the equal nothing of difference
Statistical significance (P ＞ 0.05), is comparable.
2, curative effect determinate standard
It is effective：After treatment, diastole drops are more than 1.33kPa, and are down to normal or reduction 2.67kPa or more；
Effectively：After treatment, diastole drops 1.33-2.53kPa, and to normal；
In vain：After treatment, decompression is less than 1.33kPa, and blood pressure still maintains higher level.
3, therapy
Treatment group：It treats 1-5 groups and uses plaster made from embodiment 1-5, application method respectively：Plaster is placed in pillow
Side, upward, patient's powder lies low on pillow, and the time that lies low daily is 10-15 hours, replaces plaster every three days.
Control group：It gives and takes Nifedipine sustained release tablets, specification 10mg, 2 times/d.
4, result
By treatment in 2 months, treatment group (group 1-5) and the clinical therapeutic efficacy of control group the results are shown in Table 1.
Table 1
1 result of table is shown：Total effective rate is statistically analyzed rear significant difference (P between two groups<0.05), explanation is controlled
Treatment group curative effect is substantially better than control group.
By treatment in 2 months, the clinical symptoms for the treatment of group (group 1-5) and control group improved situation and the results are shown in Table 2.
Table 2
1 result of table is shown：Symptom improvement average time is statistically analyzed rear significant difference (P between two groups<
0.05), illustrate that treatment group's symptom improvement time is considerably less than control group.
The evaluation with toxic side effect is commented in the safety of the plaster of the present invention：
The present invention plaster clinical research observation observation in, do not find any adverse reaction or toxic side effect, to blood,
Urine, feces routine, hepatic and renal function, electrocardiogram etc. can illustrate that this plaster is safe and reliable without influence in conjunction with modern pharmacological research.
Typical case
Case 1：Zhang, man, 52 years old, hypertension history 8 years took always Nifedipine sustained release tablets, but controlling of blood pressure feelings
Condition is undesirable, feels that headache, giddy are dazzle the eyes, tinnitus, tired powerless, legs and feet stretch Qu Buli, blood pressure 180/120mmHg.Half a year
The preceding plaster using the embodiment of the present invention 2, blood pressure is reduced to 135/97mmHg after one month, and the corresponding symptom of the patient obviously subtracts
Gently, it is continuing with three months, symptom disappears substantially, and check is all gone well.
Case 2：Liu, female, 58 years old, hypertension history 15 years, blood pressure often in 160/90mmHg or more, felt headache, head
Dizzy, alliteration, palpitation and insomnia, extremity numbness.Using the plaster of the embodiment of the present invention 4, the corresponding symptom of the patient is big after one month
It take a favorable turn, blood pressure is down to 142/108mmHg, is continuing with 4 months, and blood pressure is down to normally, and check is all gone well.
Case 3：Mr. Wang, male, 46 years old, hypertension history 4 years, long-term dizziness headache, limb fiber crops, mesh was puckery, insomnia, hidrosis, blood
It is 200/140mmHg when pressing highest.Using the plaster of the embodiment of the present invention 1, blood pressure is down to 177/117mmHg after a week, two weeks
Blood pressure is down to 148/106mmHg afterwards, and the symptoms such as dizziness headache limb fiber crops are substantially reduced, after continue medication and consolidate curative effect, disease in three months
Shape disappears substantially, and check blood pressure restores normal.
Case 4：Flood certain, female, before 41 years old, 1 year find have dizziness headache, headache, alliteration, dizziness, insomnia the phenomenon that, curing
Institute checks that blood pressure is up to 200/121mmHg.Using the plaster of the embodiment of the present invention 5, blood pressure is down to 163/ after one month
106mmHg is down to normally using blood pressure after 4 months, and various symptoms completely disappear.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention belong to the scope of protection of present invention.
Claims (8)
1. a kind of plaster of blood pressure lowering, which is characterized in that the plaster is made of the raw material of following parts by weight：
15-30 parts of wild jujube root, 10-20 parts of Prunella vulgaris, 10-30 parts of pueraria lobata, 10-30 parts of cassia seed, 6-15 parts of ginkgo leaf, decumbent corydalis tuber
5-15 parts, 10-30 parts of palma, 10-25 parts of Herba Epimedii, 5-15 parts of keel, 5-15 parts of valerian, 15-30 parts of hawthorn, root of bidentate achyranthes 5-20
Part, 5-10 parts of uncaria, 5-20 parts of chrysanthemum, 5-20 parts of magnetite, 10-20 parts of Polygonum multiflower knotweed, 5-15 parts of the seed of feather cockscomb.
2. the plaster of blood pressure lowering according to claim 1, which is characterized in that the plaster by following parts by weight raw material
Composition：
20-30 parts of wild jujube root, 10-20 parts of Prunella vulgaris, 10-20 parts of pueraria lobata, 20-30 parts of cassia seed, 8-12 parts of ginkgo leaf, decumbent corydalis tuber
10-15 parts, 15-25 parts of palma, 20-25 parts of Herba Epimedii, 5-15 parts of keel, 5-10 parts of valerian, 20-30 parts of hawthorn, root of bidentate achyranthes 12-
18 parts, 5-10 parts of uncaria, 10-20 parts of chrysanthemum, 5-10 parts of magnetite, 15-20 parts of Polygonum multiflower knotweed, 10-15 parts of the seed of feather cockscomb.
3. the plaster of blood pressure lowering according to claim 1, which is characterized in that the plaster by following parts by weight raw material
Composition：
25 parts of wild jujube root, 20 parts of Prunella vulgaris, 20 parts of pueraria lobata, 25 parts of cassia seed, 10 parts of ginkgo leaf, 12 parts of decumbent corydalis tuber, palma 20
Part, 20 parts of Herba Epimedii, 10 parts of keel, 8 parts of valerian, 25 parts of hawthorn, 15 parts of the root of bidentate achyranthes, 10 parts of uncaria, 15 parts of chrysanthemum, 10 parts of magnetite,
15 parts of Polygonum multiflower knotweed, 10 parts of the seed of feather cockscomb.
4. a kind of preparation method of the plaster of blood pressure lowering described in claim 1, which is characterized in that the preparation method include with
Lower step：
1) feedstock processing：The raw material of corresponding parts by weight is weighed, is crushed spare；
2) spice extracts：It takes sesame oil to set in pot, the raw material got ready is put into after low-grade fever, be heated to 210-230 DEG C, and constantly stir
Mix, until raw material is fried to sallow inside the dark brown of surface, it is fried it is good after fishing go the dregs of a decoction to get medicine oil；
3) it refines oil：It takes above-mentioned medicine oil to continue to temper, waits for that oil temperature rises to 310-330 DEG C, until medicine oil dropping into a bead, has been refined oil
At；
4) pilling and pasting：The medicine oil refined is slightly cold from fire, when oil temperature is down to 280-300 DEG C, medicine oil is added portionwise in yellow lead
In, while being continuously agitated along a direction, until medicine oil is at the continuous lotion of sticky, wire drawing；
5) it releases fire-toxin：The lotion that will have been refined, is put into cold water and impregnates, and changes water daily 1 time, impregnates 5-7 days；
6) plaster is spread out：The lotion to have released fire-toxin is heated to fusing at a temperature of 40-60 DEG C, is then evenly coated in medicated plaster cloth i.e.
It can.
5. the preparation method of the plaster of blood pressure lowering according to claim 4, which is characterized in that the raw material grinding in step 1)
At fine powder, 200-300 mesh sieve is crossed.
6. the preparation method of the plaster of blood pressure lowering according to claim 4, which is characterized in that count in parts by weight, sesame
Oil is 1000-1200 parts.
7. the preparation method of the plaster of blood pressure lowering according to claim 4, which is characterized in that count in parts by weight, yellow lead
It is 500-600 parts.
8. application of the plaster described in claim 1 in the drug for preparing treatment hypertension.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810373484.2A CN108310159A (en) | 2018-04-24 | 2018-04-24 | A kind of plaster of blood pressure lowering and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810373484.2A CN108310159A (en) | 2018-04-24 | 2018-04-24 | A kind of plaster of blood pressure lowering and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108310159A true CN108310159A (en) | 2018-07-24 |
Family
ID=62895962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810373484.2A Pending CN108310159A (en) | 2018-04-24 | 2018-04-24 | A kind of plaster of blood pressure lowering and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108310159A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658757A (en) * | 2020-07-29 | 2020-09-15 | 石琴 | Traditional Chinese medicine composition, preparation method thereof, black plaster and application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1286111A (en) * | 1999-08-27 | 2001-03-07 | 侯德善 | Chinese-medicinal prescription for lowering blood pressure |
| CN1868532A (en) * | 2005-05-23 | 2006-11-29 | 邓大勇 | Medicine for treating hypertension |
| CN101804111A (en) * | 2010-05-10 | 2010-08-18 | 北京华仁堂药物科技有限公司 | Traditional Chinese medicine for treating high blood pressure and preparation method thereof |
| CN107669766A (en) * | 2017-10-31 | 2018-02-09 | 肖燕萍 | Health care pillow for bringing high blood pressure down Chinese medicine preparation |
-
2018
- 2018-04-24 CN CN201810373484.2A patent/CN108310159A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1286111A (en) * | 1999-08-27 | 2001-03-07 | 侯德善 | Chinese-medicinal prescription for lowering blood pressure |
| CN1868532A (en) * | 2005-05-23 | 2006-11-29 | 邓大勇 | Medicine for treating hypertension |
| CN101804111A (en) * | 2010-05-10 | 2010-08-18 | 北京华仁堂药物科技有限公司 | Traditional Chinese medicine for treating high blood pressure and preparation method thereof |
| CN107669766A (en) * | 2017-10-31 | 2018-02-09 | 肖燕萍 | Health care pillow for bringing high blood pressure down Chinese medicine preparation |
Non-Patent Citations (1)
| Title |
|---|
| 全国中等卫生学校试用教材《药剂学》编写组: "《药剂学》", 31 May 1980, 浙江科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658757A (en) * | 2020-07-29 | 2020-09-15 | 石琴 | Traditional Chinese medicine composition, preparation method thereof, black plaster and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102742691B (en) | Health-care tea drink with blood pressure lowering effect and preparation method thereof | |
| CN101810685B (en) | Chinese medicinal composition for treating gonitis and preparation method thereof | |
| CN103041209A (en) | Chinese herbal preparation for curing deficiency of kidney-yin and preparation method thereof | |
| CN104825914A (en) | Traditional Chinese medicinal preparation for assisted treatment of breast cancer | |
| CN1109554C (en) | Medicine for treating allergic purpura | |
| CN103479754B (en) | Hypotensive drug and preparation method thereof | |
| CN105106446A (en) | Healthcare tea used for lowering blood pressure and preparation method thereof | |
| CN103919910A (en) | Medicine for treating coronary heart disease | |
| CN108310159A (en) | A kind of plaster of blood pressure lowering and preparation method thereof | |
| CN102406799A (en) | Cataplasm paste for treating diabetes and hypertension complicated with coronary heart disease and preparation method thereof | |
| CN105232987A (en) | Traditional Chinese medicine promoting neurosurgery postoperative rehabilitation | |
| CN103860773A (en) | Traditional Chinese medicine composition for treating myocardial ischemia and preparation method thereof | |
| CN104491718B (en) | Medicine for treating liver-depression and phlegm-stasis type mammary gland hyperplasia and preparation method | |
| CN106138974A (en) | A kind of pharmaceutical composition improving Qi deficiency physique and a kind of medicine brick and preparation method thereof | |
| CN102988747B (en) | Aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and preparation method thereof | |
| CN104645063A (en) | Pills for treating hyperplasia of mammary glands and preparation method thereof | |
| CN105250569A (en) | Traditional Chinese medicine pill for treating peripheral neuritis and preparation method | |
| CN111265609A (en) | Traditional Chinese medicine composition for adjuvant treatment of true myopia and preparation method thereof | |
| CN104906394A (en) | Traditional Chinese medicine for treating liver and kidney yin deficiency and qi and blood deficiency type hypertension | |
| CN104940679A (en) | Health preserving capsule for treating diabetes, and preparation method thereof | |
| CN104689205A (en) | Traditional Chinese preparation for treating insomnia and dreamful sleep and preparation method thereof | |
| CN105194433A (en) | Traditional Chinese medicine composition for medically treating body deficiency syndromes of the aged | |
| CN104940719A (en) | Spleen and kidney tonifying pill for relieving uremia and preparation method of spleen and kidney tonifying pill | |
| CN104825879A (en) | Spleen-strengthening and kidney-tonifying capsule for clinical nursing and preparation method thereof | |
| CN104138496A (en) | Pills for treating dysuria of the old |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180724 |
|
| RJ01 | Rejection of invention patent application after publication |