A kind of sample is coated with piece treating apparatus
Technical field
The present invention relates to medical science sample processing device, especially relate to a kind ofly automatically load, smear, the reliable sample of operation standard is coated with piece treating apparatus.
Background technology
Pathology are as the important support of medical system, just for the whole mankind's health is made major contribution.As pathological important component part, the work of Hospital Pathological Department tissue section strain is that pathological section has been implemented to the relevant early stage pre-service of this pathological section before medical science sample properties is judged alternately, repeatedly by operations such as dewaxing, reparation, dyeing, cleanings; Its standardization, hommization are carried out, and more need product unit in building the process of product, aggressive the theory of standardization, hommization are incorporated to product fully, better to serve human health.At present sample smear being processed is all generally manually to carry out, inefficiency not only, and due to manual operation, each operation is all inconsistent, can not guarantee that each operation is all that standard is reliable, has influence on the carrying out of follow-up work.Publication number is CN102971616A, name is called for producing the automated system of cell smear, it comprises surface, smear blade, and blade movement mechanism, blade movement mechanism comprises motor, smear blade linkage and controller, and controller is configured to for smear blade is moved along X-axis with along the y-axis shift perpendicular to X-axis with respect to surface, so that cell adheres to from the teeth outwards in the mode of layer.Although this device has been realized automatic smear, when this device once can only be to carrying out smear when a sample, work efficiency is lower.
Summary of the invention
The present invention is mainly that to solve in prior art artificial smear operating efficiency low, and has the nonstandard insecure problem of operation, provides a kind of and automatically loads, smear, and the reliable sample of operation standard is coated with piece treating apparatus.
Above-mentioned technical matters of the present invention is mainly solved by following technical proposals: a kind of sample is coated with piece treating apparatus, comprise two Cam rests, on two Cam rests, be separately installed with coaxial connected cam, heating module seat is installed on Cam rest top, heating module seat top is provided with sample assembly carrier, sample assembly carrier is movably arranged on two Cam rests and with cam and coordinates and be connected, sample tray is arranged in sample assembly carrier, on sample tray, place a plurality of sample wave carrier pieces, on sample wave carrier piece, be provided with cover plate, on heating module seat, be provided with and coordinate the smear topworks that carries out transverse shifting with cam, described cover plate and the activity of smear topworks are connected.Apparatus of the present invention can be carried out load lock to wave carrier piece, then carry out smear, realized a step automatic operation, completed the batch processing of applicable sample in immunohistochemical stainer dyeing course, not only make to operate more standard, stable, reliable, but also improved work efficiency.Specimen slide is placed in sample tray, and sample tray is put in sample assembly carrier, and this sample assembly carrier matches with the cam on Cam rest, and cam can drive sample assembly carrier to move up and down.In cam work process, cam driven sample assembly carrier moves down, and makes the wave carrier piece on sample assembly carrier contact and lock with heating module seat below.Cam simultaneously Hai Yu smear topworks is connected, after driving sample assembly carrier to move down, also can drive smear topworks to carry out transverse shifting, smear topworks moves the cover plate that drive is connected with it and moves, thereby has realized the process of sample on wave carrier piece being carried out to smear.
As a kind of preferred version, described sample assembly carrier comprises top board and is arranged on the motion bracket of top board both sides, on described Cam rest, be vertically provided with guide pole, described motion bracket is enclosed within on guide pole, on the guide pole between motion bracket bottom and Cam rest, be provided with power assistant spring, position below motion bracket is positioned at cam is provided with the first buffering wheel, and described the first buffering wheel contacts with cam working face.The first buffering wheel on motion bracket contacts with cam in the below of cam, simultaneously under the elastic force effect of power assistant spring, the power making progress to motion bracket, is pressed on cam the first buffering wheel on motion bracket, and motion bracket is enclosed within on guide pole can carry out upper and lower displacement.Cam can change the position of the first buffering wheel while rotating, and under the effect of guide pole, the first buffering wheel conversion of motion is motion bracket moving up and down on guide pole.
As a kind of preferred version, described cam is constituted by external cam and cam ring two parts, described external cam and cam ring coaxially arrange and are arranged to one, on described external cam outside, be provided with the second buffering wheel coordinating with smear topworks, described cam ring comprises the first workplace and the second workplace, described the first workplace from starting point to terminal curvature reduce gradually, described the second workplace is the arc surface that curvature is identical, at the starting point place of described the first workplace, be bent to form the limited impression of restricted reference position, described the first buffering wheel contacts with cam ring workplace.When rotating, this cam first by cam ring, partly drive the first buffering wheel to move, the first workplace of cam ring is the face that curvature reduces gradually, when rotating, cam ring can be gradually to pressing down the first buffering wheel, motion bracket is moved downward, from top board is moved down, the supporting plate on top board is locked mutually with heating film group seat.When cam ring forwards the second workplace to, finish to press down the action of the first buffering wheel, the second workplace curvature is the same, when the second workplace work, cam is keeping the pressing down of the first buffering wheel, and the second buffering wheel also produces displacement simultaneously, and the second buffering wheel drives the action of smear topworks.The second buffering wheel is positioned at the rear portion of the first buffering wheel rotation direction, and when the first buffering wheel finishes when the first workplace rotates, this second buffering wheel starts to match and contact with smear topworks.
As a kind of preferred version, between described two cams, by cam shaft coupling, be connected, on cam shaft coupling, be provided with follower gear, in heating module seat bottom, be provided with motor-driven driving gear, driving gear is meshed with follower gear, cam place is provided with and detects the first alignment sensor whether supporting plate locks mutually with heating module seat therein, and detect cam the second complete alignment sensor of whether working, on the convex wheel face of this cam, be also provided with the blend stop matching with first, second alignment sensor.The first alignment sensor and the second alignment sensor are grating sensor, and the rotation by blend stop in alignment sensor carrys out trigger pip.Whether the first alignment sensor detects supporting plate and locks mutually with heating module seat, detect the terminal whether the first buffering wheel arrives cam ring the first workplace, when the first buffering wheel arrives the first face end, now blend stop produces the first alignment sensor, trigger pip.Whether the second alignment sensor detection cam works complete is whether blend stop produces the second alignment sensor, if it is trigger pip.By alignment sensor, can better more accurately control the rotation of cam.
As a kind of preferred version, in the both sides of described top board bottom surface length, be connected with respectively the guide rail of L-type, two side flangings of described pallet length are formed with leg rest, pallet inserts in the space of two guide rails formation, leg rest is placed on guide rail, on tray surface, being provided with some dividing plates is separated into tray surface a plurality of for placing the groove position of microslide, front and back end, groove position has rest portion, hollow out in the middle of groove position, be positioned in the rest portion of front end and be provided with stopper slot, stopper slot front end is in the upper shed of pallet side, stopper slot rear end is horn-like opening, and be respectively arranged with and put edge in horn-like opening both sides, described putting along being incline structure.The guide rail of both sides, top board bottom surface arranges in opposite directions, forms the space of inserting for supporting plate, and when supporting plate is inserted in top board, the leg rest of supporting plate is placed on guide rail, then pushes.On supporting plate, place a plurality of wave carrier pieces, wave carrier piece is placed in respectively in each groove position, the rear and front end of wave carrier piece is placed on respectively in rest portion, and center section hollow out, microslide two ends part is in addition exposed on bracket bottom surface, and wave carrier piece just can contact with the heating module of bracket below like this.
As a kind of preferred version, the shape of described cover plate matches with groove position shape, cover forward end is provided with discount, discount matches with the horn-like opening shape in stopper slot rear end with cover plate main body connecting portion shape, in cover plate bottom, be also provided with draw runner, the front end of draw runner is arcuate structure, described discount front end both sides are provided with draw-in groove, make discount front end form I-shaped buckle structure, this draw-in groove bottom is up-narrow and down-wide funnel structure, after cover plate is placed on groove position, discount front end stretches out outside groove position, and this discount and the activity of smear topworks are connected.The action of smear topworks, pulls cover plate to move forward, and skewed shelf is designed in stopper slot rear end, cover plate two bottom sides arranges draw runner simultaneously, and draw runner front end is arcuate structure, these all make cover plate to be drawn out convenient, smoothly groove position, realize the operation to wave carrier piece smear.Discount Front-end Design becomes I-shaped, is convenient to be fastened and connected with smear topworks, and draw-in groove lower end is designed to funnel-form, is convenient to buckling device and buckles into draw-in groove.
As a kind of preferred version, smear topworks comprises the slide plate that is arranged on heating module seat both sides, slide plate is connected with the slide rail of heating module seat both sides, between two slide plates, be connected with web joint, it is anterior that web joint is positioned at heating module seat, on web joint, there are some claws that match with cover plate, claw top is provided with catching groove, described cover plate discount is fastened in the catching groove of claw, under described slide plate lateral, flange is formed with the Motor execution plate coordinating with cam, on Motor execution plate, be provided with the first locating slot, described the second buffering wheel is entrapped in the first locating slot when cam forwards the second workplace to, on Motor execution plate, be also provided with the second groove, on described motion bracket, be provided with register pin, register pin is entrapped in the second locating slot.This slide plate bottom, for having the slide block of cutter T-slot body, is fixed with respectively T-shaped slide rail in heating module seat both sides, and sliding plate sleeve is on slide rail.Web joint is connected to the front end of two slide plates, and web joint is the front portion that is positioned at heating module seat, and the claw on web joint and the cover plate head on supporting plate are fastened and connected, and slide plate moves drive claw and moves forward like this, and claw will pull cover plate to move.The Motor execution plate that moves through of slide plate carries out, the first locating slot on Motor execution plate and the second locating slot are all the grooves vertically arranging, the first locating slot opening is following Motor execution plate, the first locating slot consists of two parts, starting to be one section is deep-slotted chip breaker, coordinates the second buffering wheel to slip into, and is straight trough afterwards, the second buffering wheel rotates, and by straight trough, the displacement of the second buffering wheel is converted into the displacement forward of slide plate.When cam initial position, the second buffering wheel does not snap in the first locating slot, when cam ring first workplace of cam completes, rotates while entering the second workplace, and the second buffering wheel starts to snap in the first locating slot.The second locating slot be also opening Motor execution plate below, its length is equivalent to the distance of motion bracket upper and lower displacement, at cam during at initial position, register pin is to be stuck in the second locating slot, make like this Motor execution plate cannot carry out displacement forward, locked and carry out Motor execution plate, prevented that pallet from carrying out smear action before non-locking.When cam has turned the first workplace, now motion bracket has moved down a segment distance, and register pin has departed from the second locating slot, release Motor execution plate, make next can carry out moving forward to drive claw to drag cover plate to complete smear action.
As a kind of preferred version, on described heating module seat, be provided with a plurality of heating modules corresponding with groove position on supporting plate respectively, each heats and between module, has gap, when pallet moves down on heating module seat, the lower partition on pallet is embedded in respectively in gap, forms the locking with heating module seat.Heating module is for carrying out heating operation to the sample on microslide, top moves down pallet and also moves down thereupon, move down and know that pallet is placed on heating module seat, now a heating module correspondence contacts with a groove position, and the lower partition of separation trough position is embedded in the gap between two heating modules, forms indenting structure, pallet and heating module seat are locked mutually, pallet can not be drawn out of again, guarantee sample, load the reliability of demand position.
As a kind of preferred version, on heating module seat, be provided with a plurality of waste collection mouths, in heating module seat, be also provided with collecting chamber, each waste collection mouth is communicated to collecting chamber, described collecting chamber bottom is provided with waste liquid recovery port, on collecting chamber, be also provided with negative port, described, around heating module seat front portion and both sides, be also provided with waste collection dish.This waste collection mouth is the main mouth of collecting, it is positioned at the front end of the heating module of heating module seat, liquid on wave carrier piece easily flow in waste collection mouth, negative port in waste collection chamber connects actuating unit, actuating unit is air extractor, air extractor forms negative pressure waste liquid is drawn in waste collection mouth, and waste liquid is converged in collecting chamber, and waste liquid reclaims by waste liquid recovery port again.A small amount of waste liquid also can flow in waste collection dish in addition.
Therefore, advantage of the present invention is: realized wave carrier piece loading, smear one step automatic operation, realized the batch processing of applicable sample in immunohistochemical stainer dyeing course, not only made to operate more standard, stable, reliable, but also improved work efficiency.
Accompanying drawing explanation
Accompanying drawing 1 is a kind of structural representation of the present invention;
Accompanying drawing 2 is the structural representations at the another kind of visual angle of the present invention;
Accompanying drawing 3 is structural representations of side of the present invention;
Accompanying drawing 4 is a kind of structural representations of pallet in the present invention;
Accompanying drawing 5 is a kind of structural representations of cover plate of the present invention;
Accompanying drawing 6 is a kind of structural representations of cam of the present invention;
Accompanying drawing 7 is with a kind of structural representation of the cam of alignment sensor in the present invention.
Accompanying drawing 8 is the structure for amplifying schematic diagram at A place in accompanying drawing 1.
1- cam bracket 2- cam 3- sample assembly carrier 4- 5- 6- guide rod bracket of roof movement 7- boost spring 8- cam shaft coupling 9- negative pressure port 10- waste recycling port 11- driving gear driven gear 12- 13- skate 14- motion of the executive board 15- first buffer wheel 16- second buffer wheel 17- heating module seat 18- heating module 19- waste liquid collecting port the 20- connection in 22- 21- claw buckle slot 23- waste liquid collecting disk 24- guide 25- the first locating groove and 26- second positioning grooves 27- pin 28- tray 29- partition 30- slot 31- footrest 32- placing part 33- the limiting groove along the 35- 36- 34- put the cover plate buckle head 37- card slot 38- slider 39- cam in cam 41- 40- the first working face 42- second working face 43- the first positioning sensor 44- second sensor 45- retaining strip 46- slide slide 47- 48- limit groove.
Embodiment
Below by embodiment, and by reference to the accompanying drawings, technical scheme of the present invention is described in further detail.
Embodiment:
A kind of sample of the present embodiment is coated with piece treating apparatus, as depicted in figs. 1 and 2, comprise two Cam rests 1, cam is arranged on Cam rest, be arranged on the heating module seat 17 on Cam rest top, the sample assembly carrier 3 that is arranged on heating module seat top, sample assembly carrier is movably connected on Cam rest in both sides, and matches and contact with cam.In sample assembly carrier, insert and be placed with pallet 28, microslide is placed on pallet, on microslide, also establishing son has cover plate 35, on heating module seat, is provided with and coordinates the smear topworks that carries out transverse shifting with cam, and cover plate and the activity of smear topworks are connected.
As shown in figures 1 and 3, sample assembly carrier 3 includes top board 5 and is arranged on the motion bracket 4 of top board both sides, this motion bracket is square framework, on Cam rest 1, be vertically provided with guide pole 6, motion bracket is enclosed within on guide pole, this guide pole is through entablature part and the sill part of motion bracket, on the bottom of motion bracket sill and the guide pole between Cam rest, be provided with power assistant spring 7, motion bracket by cam frame in frame, on the sill of the position below motion bracket is positioned at cam 2, be provided with the first buffering wheel 15, the first buffering wheel contacts with cam working face, power assistant spring is pressed on cam the first buffering wheel.
As shown in Figure 4, two side flangings of pallet 28 length are formed with leg rest 31, and as shown in Figure 3, the guide rail that on top board bottom surface, the both sides of length are connected with respectively 24, two L-types of guide rail of L-type forms the space of inserting for pallet, and when pallet inserts, leg rest is placed on guide rail.On tray surface, being provided with some dividing plates 29 is separated into tray surface a plurality of for placing the groove position 30 of microslide, front and back end, groove position has rest portion 32, hollow out in the middle of groove position, be positioned in the rest portion of front end and be provided with stopper slot 33, stopper slot front end is in the upper shed of pallet side, stopper slot rear end is horn-like opening, and is respectively arranged with and puts along 34 in horn-like opening both sides, puts along being incline structure.In one end of pallet, be provided with and hold plate in addition, be convenient to pallet to push in top board.Wave carrier piece is placed in groove position, and wave carrier piece two ends rest in rest portion, and cover plate is placed on wave carrier piece.As shown in Figure 5, the shape of cover plate 35 matches with groove position 30 shapes, cover forward end is provided with discount 36, discount matches with the stopper slot 33 horn-like opening shapes in rear end with the shape of cover plate main body connecting portion, be the shoulder structure of inclination, just in time can be embedded in the horn-like opening in stopper slot rear end.In cover plate bottom, be also provided with draw runner 38, the front end of draw runner is arcuate structure, described discount front end both sides are provided with draw-in groove 37, make discount front end form I-shaped buckle structure, this draw-in groove bottom is up-narrow and down-wide funnel structure, after cover plate is placed on groove position, discount front end stretches out outside groove position, and this discount and the activity of smear topworks are connected.
Between two cams, by cam shaft coupling 8, be connected, on cam shaft coupling, be provided with follower gear 12, bottom at heating module seat 17 is provided with motor-driven driving gear 11, driving gear is Worm-gear type with follower gear and is meshed, and driving gear will convert follower gear to around vertical axes and rotate around transverse axis.As shown in Figure 6, cam 2 is constituted by external cam 39 and cam ring 40 two parts, and external cam and cam ring coaxially arrange, and manufacture one, as shown in Figure 3, on external cam outside, is provided with the second buffering wheel 16 coordinating with smear topworks.The first buffering wheel contacts with cam ring workplace, cam ring workplace comprises the first workplace 41 and the second workplace 42, this first workplace at starting point place, be bent to form restricted the first buffering wheel limited impression 48, the first workplaces of reference position from starting point to terminal curvature reduce gradually.The second workplace is the arc surface that curvature is identical.Two cams are divided into again respectively positioning cam and inverted cam, the structure of two cams is consistent, as shown in Figure 7, on positioning cam, locate to be also provided with and detect the first alignment sensor 43 whether supporting plate locks mutually with heating module seat, and detect cam the second complete alignment sensor 44 of whether working, first, the second alignment sensor is all grating sensor, on the convex wheel face of this positioning cam, be provided with and first, the blend stop 45 that the second alignment sensor matches, first, the second alignment sensor judges by detecting blend stop whether positioning cam has turned the first workplace, whether worked complete.
As shown in Figure 2, on heating module seat 17, be provided with a plurality of heating modules 18 corresponding with groove position 30 on supporting plate respectively, each heats and between module, has gap, when pallet moves down on heating module seat, dividing plate 29 bottoms on pallet are embedded in respectively in gap, form the locking with heating module seat.On heating module seat, be provided with a plurality of waste collection mouths 19, in heating module seat, be also provided with collecting chamber, each waste collection mouth is communicated to collecting chamber, as shown in Figure 1, collecting chamber bottom is provided with waste liquid recovery port 10, on collecting chamber, be also provided with negative port 9, negative port connects air extraction device, in and both sides anterior around heating module seat, is also provided with waste collection dish 23.
As shown in figures 1 and 3, smear topworks comprises the slide plate 13 that is arranged on heating module seat both sides, as shown in Figure 8, in heating module seat both sides, be provided with slide rail 46, slide rail is T-shaped structure, in slide plate bottom, be provided with slide block, slide block is provided with the inverted T-shaped cell body matching with slide rail, slide plate is connected on slide rail, between two slide plates, be connected with web joint, it is anterior that this web joint is positioned at heating module seat, as shown in Figure 2, on web joint, there are some claws that match with cover plate 21, claw top is provided with catching groove 22, the discount of cover plate is fastened in the catching groove of claw, cover plate forms and is connected with smear topworks like this.Under slide plate lateral, flange is formed with the Motor execution plate 14 coordinating with cam 2, on Motor execution plate, be provided with the first locating slot 25, the second buffering wheel 16 is entrapped in the first locating slot when cam forwards the second workplace to, on Motor execution plate, be also provided with the second locating slot 26, on motion bracket, be provided with register pin 27, register pin is entrapped in the second locating slot.
When work, specimen slide is put in pallet, then pallet is inserted in top board.Starter motor drives driving gear, driving gear band moving cam shaft coupling rotates, cam starts to rotate, and the first workplace of cam ring contacts with the first buffering wheel, in rotation process, cam ring presses down the first buffering wheel gradually, motion bracket is moved down, be about to top and move down, until cam ring has turned the first workplace, now the supporting plate on top board be just in time placed on heating module seat above, pallet with heat module seat and lock mutually.Cam continues rotation, and the first buffering wheel contacts with the second workplace, keeps the downward pressure of motion bracket.And now the second buffering wheel in external cam starts to enter the first locating slot on Motor execution plate, register pin on motion bracket has departed from the second locating slot on Motor execution plate simultaneously, along with cam rotates, the second buffering wheel actuation movement is carried out plate transverse shifting, so just drive also transverse shifting of claw, claw pulls cover plate, completes the action of wave carrier piece smear, cam rotation is until trigger the second alignment sensor, end-of-job.
Specific embodiment described herein is only to the explanation for example of the present invention's spirit.Those skilled in the art can make various modifications or supplement or adopt similar mode to substitute described specific embodiment, but can't depart from spirit of the present invention or surmount the defined scope of appended claims.
Although more used the terms such as Cam rest, cam, sample assembly carrier, motion bracket, top board herein, do not got rid of the possibility of using other term.Use these terms to be only used to describe more easily and explain essence of the present invention; They are construed to any additional restriction is all contrary with spirit of the present invention.