CN104080476A - 用于呼吸道合胞病毒的重组纳米颗粒rsv f疫苗 - Google Patents

用于呼吸道合胞病毒的重组纳米颗粒rsv f疫苗 Download PDF

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Publication number
CN104080476A
CN104080476A CN201280059282.1A CN201280059282A CN104080476A CN 104080476 A CN104080476 A CN 104080476A CN 201280059282 A CN201280059282 A CN 201280059282A CN 104080476 A CN104080476 A CN 104080476A
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rsv
albumen
vlp
seq
cell
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G.史密斯
吴颖运
M.马萨尔
刘晔
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Novavax Inc
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Novavax Inc
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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CN201280059282.1A 2011-09-30 2012-09-27 用于呼吸道合胞病毒的重组纳米颗粒rsv f疫苗 Pending CN104080476A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510769961.3A CN105381457A (zh) 2011-09-30 2012-09-27 用于呼吸道合胞病毒的重组纳米颗粒rsv f疫苗

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161542040P 2011-09-30 2011-09-30
US61/542,040 2011-09-30
US201161542721P 2011-10-03 2011-10-03
US61/542,721 2011-10-03
US201261611834P 2012-03-16 2012-03-16
US61/611,834 2012-03-16
US201261614286P 2012-03-22 2012-03-22
US61/614,286 2012-03-22
PCT/US2012/057546 WO2013049342A1 (en) 2011-09-30 2012-09-27 Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus

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CN201510769961.3A Pending CN105381457A (zh) 2011-09-30 2012-09-27 用于呼吸道合胞病毒的重组纳米颗粒rsv f疫苗

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US (4) US20130122032A1 (https=)
EP (1) EP2760469A4 (https=)
JP (1) JP2014530010A (https=)
KR (1) KR20140077169A (https=)
CN (2) CN104080476A (https=)
AU (1) AU2013201495B2 (https=)
BR (1) BR112014007616A2 (https=)
CA (1) CA2849471A1 (https=)
HK (1) HK1222125A1 (https=)
IL (1) IL231637A0 (https=)
MX (1) MX2014003777A (https=)
RU (1) RU2014117068A (https=)
SG (2) SG10201602434UA (https=)
WO (1) WO2013049342A1 (https=)

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CN107050446A (zh) * 2017-04-19 2017-08-18 武汉博沃生物科技有限公司 经修饰的季节流感‑rsv联合疫苗及其制备方法
CN108025057A (zh) * 2015-09-02 2018-05-11 扬森疫苗与预防公司 稳定化的病毒i类融合蛋白
CN108348593A (zh) * 2015-08-31 2018-07-31 泰克诺瓦克斯股份有限公司 基于人呼吸道合胞病毒(hrsv)病毒样颗粒(vlps)的疫苗
CN113543803A (zh) * 2019-02-28 2021-10-22 Km生物医药股份公司 Rsv f/g嵌合疫苗
CN115461076A (zh) * 2020-04-02 2022-12-09 扬森疫苗与预防公司 稳定化的疫苗组合物
CN115720581A (zh) * 2020-01-27 2023-02-28 诺瓦瓦克斯股份有限公司 冠状病毒疫苗配制品
CN116063551A (zh) * 2016-04-05 2023-05-05 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f蛋白
CN116744905A (zh) * 2020-11-27 2023-09-12 韩国科学技术研究院 表达rsvf的外泌体及其用途
CN113855796B (zh) * 2021-07-30 2024-01-26 河北医科大学 卡介苗作为呼吸道合胞病毒灭活疫苗佐剂的应用
CN117986382A (zh) * 2022-11-04 2024-05-07 北京康乐卫士生物技术股份有限公司 针对rsv的重组亚单位疫苗及其应用
WO2024260446A1 (zh) * 2023-06-21 2024-12-26 深圳深信生物科技有限公司 呼吸道合胞病毒(rsv)疫苗
WO2025026448A1 (zh) * 2023-08-03 2025-02-06 广州穗和生物技术有限公司 修饰的呼吸道合胞病毒f蛋白及其用途
WO2025051250A1 (zh) * 2023-09-07 2025-03-13 北京科兴中维生物技术有限公司 呼吸道合胞病毒f蛋白及其应用

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US20150110825A1 (en) * 2013-09-24 2015-04-23 Massachusetts Institute Of Technology Self-assembled nanoparticle vaccines
CN105087643A (zh) * 2014-04-16 2015-11-25 中国科学院上海巴斯德研究所 重组表达人呼吸道合胞病毒f1蛋白胞外区的方法及表达系统
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CN106547635B (zh) 2015-09-18 2020-10-09 阿里巴巴集团控股有限公司 一种作业的操作重试方法和装置
EP3393512B1 (en) 2015-12-23 2025-11-19 Pfizer Inc. Rsv f protein mutants
CN106124767A (zh) * 2016-05-12 2016-11-16 广州瑞辉生物科技股份有限公司 呼吸道合胞病毒IgA抗体检测试纸条及其检测方法
CN110352072A (zh) * 2016-10-03 2019-10-18 马萨诸塞大学 用于免疫免疫前受试者以抵抗呼吸道合胞病毒(rsv)的方法
SG11201908376UA (en) * 2017-03-15 2019-10-30 Novavax Inc Methods and compositions for inducing immune responses against clostridium difficile
KR102774312B1 (ko) 2017-04-04 2025-03-05 유니버시티 오브 워싱톤 파라믹소바이러스 및/또는 뉴모바이러스 f 단백질을 표시하는 자가-조립 단백질 나노구조체 및 이의 용도
WO2019023196A1 (en) 2017-07-24 2019-01-31 Novavax, Inc. METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISEASE
WO2019063844A1 (en) * 2017-09-29 2019-04-04 Universiteit Antwerpen VACCINATION AGAINST SYNCYTIAL RESPIRATORY VIRUS
CA3095216A1 (en) 2018-02-28 2019-09-06 University Of Washington Self-asssembling nanostructure vaccines
EP3768308A4 (en) 2018-03-19 2022-01-26 Novavax, Inc. MULTIVALENT INFLUENZA NANOPARTICLE VACCINES
WO2020076141A1 (ko) * 2018-10-12 2020-04-16 에스케이바이오사이언스 주식회사 재조합 rsv 생백신주 및 이의 제조 방법
US12370252B2 (en) 2018-10-29 2025-07-29 Emory University RSV virus-like particles and methods of use thereof
KR102725189B1 (ko) * 2018-11-01 2024-10-31 에스케이바이오사이언스(주) 재조합 호흡기 세포융합 바이러스 f 단백질 및 이를 포함하는 백신 조성물
CN110229219B (zh) * 2019-06-21 2021-03-30 中国科学院武汉病毒研究所 一种新型的呼吸道合胞病毒疫苗抗原的制备方法及其用途
US10953089B1 (en) 2020-01-27 2021-03-23 Novavax, Inc. Coronavirus vaccine formulations
CN118434756A (zh) * 2021-11-19 2024-08-02 达冕生物有限公司 核糖核酸呼吸道合胞病毒（rsv）疫苗的组合物和方法
KR102785012B1 (ko) * 2021-12-14 2025-03-20 경희대학교 산학협력단 Rsv 항원 단백질을 포함하는 바이러스 유사입자 및 이를 이용한 백신
WO2024050015A1 (en) * 2022-09-01 2024-03-07 Novavax, Inc. Downstream process for purification of viral proteins with hydrophobic membrane domain for use in vaccine compositions
WO2024259624A1 (en) * 2023-06-21 2024-12-26 Shenzhen Genius Biotech Service Co. Ltd A modified rsv f protein, a nanoparticle, a composition and a vaccine against respiratory syncytial virus infection

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Cited By (15)

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Publication number Priority date Publication date Assignee Title
CN108348593A (zh) * 2015-08-31 2018-07-31 泰克诺瓦克斯股份有限公司 基于人呼吸道合胞病毒(hrsv)病毒样颗粒(vlps)的疫苗
US11324816B2 (en) 2015-08-31 2022-05-10 Technovax, Inc. Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine
CN108025057A (zh) * 2015-09-02 2018-05-11 扬森疫苗与预防公司 稳定化的病毒i类融合蛋白
CN116063551A (zh) * 2016-04-05 2023-05-05 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f蛋白
CN107050446B (zh) * 2017-04-19 2020-08-11 武汉博沃生物科技有限公司 经修饰的季节流感-rsv联合疫苗及其制备方法
CN107050446A (zh) * 2017-04-19 2017-08-18 武汉博沃生物科技有限公司 经修饰的季节流感‑rsv联合疫苗及其制备方法
CN113543803A (zh) * 2019-02-28 2021-10-22 Km生物医药股份公司 Rsv f/g嵌合疫苗
CN115720581A (zh) * 2020-01-27 2023-02-28 诺瓦瓦克斯股份有限公司 冠状病毒疫苗配制品
CN115461076A (zh) * 2020-04-02 2022-12-09 扬森疫苗与预防公司 稳定化的疫苗组合物
CN116744905A (zh) * 2020-11-27 2023-09-12 韩国科学技术研究院 表达rsvf的外泌体及其用途
CN113855796B (zh) * 2021-07-30 2024-01-26 河北医科大学 卡介苗作为呼吸道合胞病毒灭活疫苗佐剂的应用
CN117986382A (zh) * 2022-11-04 2024-05-07 北京康乐卫士生物技术股份有限公司 针对rsv的重组亚单位疫苗及其应用
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WO2025026448A1 (zh) * 2023-08-03 2025-02-06 广州穗和生物技术有限公司 修饰的呼吸道合胞病毒f蛋白及其用途
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